Cancers, Vol. 16, Pages 1696: Updates in Cancer Cachexia: Clinical Management and Pharmacologic Interventions
abbro
Despite a better understanding of the mechanisms causing cancer cachexia (CC) and development of promising pharmacologic and supportive care interventions, CC persists as an underdiagnosed and undertreated condition. CC contributes to fatigue, poor quality of life, functional impairment, increases treatment related toxicity, and reduces survival. The core elements of CC such as weight loss and poor appetite should be identified early. Currently, addressing contributing conditions (hypothyroidism, hypogonadism, and adrenal insufficiency), managing nutrition impact symptoms leading to decreased oral intake (nausea,...
Source: Cancers - April 27, 2024 Category: Cancer & Oncology Authors: Sudeep Pandey Lauren Bradley Egidio Del Fabbro Tags: Review Source Type: research
Cancers, Vol. 16, Pages 1704: Endoscopic Diagnosis of Small Bowel Tumor
oto
Recent technological advances, including capsule endoscopy (CE) and balloon-assisted endoscopy (BAE), have revealed that small intestinal disease is more common than previously thought. CE has advantages, including a high diagnostic yield, discomfort-free, outpatient basis, and physiological images. BAE enabled endoscopic diagnosis and treatment in the deep small bowel. Computed tomography (CT) enterography with negative oral contrast can evaluate masses, wall thickening, and narrowing of the small intestine. In addition, enhanced CT can detect abnormalities outside the gastrointestinal tract that endoscopy cannot ...
Source: Cancers - April 27, 2024 Category: Cancer & Oncology Authors: Tomonori Yano Hironori Yamamoto Tags: Review Source Type: research
Arenobufagin induces cell apoptosis by modulating the cell cycle regulator claspin and the JNK pathway in nasopharyngeal carcinoma cells
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 27, 2024 Category: Drugs & Pharmacology Authors: Hsin-Yu HoMu-Kuan ChenChia-Chieh LinYu-Sheng LoYi-Ching ChuangMing-Ju Hsieha Oral Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwanb Department of Otorhinolaryngology-Head and Neck Surgery, Changhua Christian Hospital, Changhua, Taiwan Source Type: research
Comparison of endoscopic thyroidectomy via the oral vestibule approach and the areola approach for papillary thyroid carcinoma
The endoscopic thyroidectomy areola approach (ETAA) has been widely applied for papillary thyroid carcinoma (PTC), but leaves scars and is not truly minimally invasive. The oral vestibular approach (ETOVA) lea... (Source: BMC Surgery)
Source: BMC Surgery - April 27, 2024 Category: Surgery Authors: Yingying Liu, Fusheng Lin, Wei Yan, Ende Lin, Penghao Kuang, Xiaoquan Hong, Yizhuo Lu, Guoyang Wu and Lianghui Li Tags: Research Source Type: research
Interdisciplinary Collaboration in Head and Neck Cancer Care: Optimizing Oral Health Management for Patients Undergoing Radiation Therapy
In conclusion, these proactive measures help minimize dental and oral complications before, during, and after treatment.PMID:38668058 | DOI:10.3390/curroncol31040155 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Tugce Kutuk Ece Atak Alessandro Villa Noah S Kalman Adeel Kaiser Source Type: research
Human papillomavirus infection: Epidemiology, biology, host interactions, cancer development, prevention, and therapeutics
This study aimed to carry out a literature review considering several aspects involving HPV infection: Global distribution, prevalence, biology, host interactions, cancer development, prevention, therapeutics, coinfection with other viruses, coinfection with bacteria, association with head and neck squamous cell carcinomas, and association with anal cancer.PMID:38666757 | DOI:10.1002/rmv.2537 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Jonas Wolf Lucas Felipe Kist Samanta Brangel Pereira Marilze Alves Quessada Helena Petek Arthur Pille Ju çara Gasparetto Maccari Mohamed Parrini Mutlaq Luiz Antonio Nasi Source Type: research
Evaluation of Serum and Salivary Lactate Dehydrogenase Levels in Patients with Oral Potentially Malignant Conditions/Lesions: A Clinical and Biochemical Study
CONCLUSION: Higher serum and salivary LDH levels in Oral Potentially malignant lesions/conditions than in control groups signifies the importance of assessing salivary LDH levels, in the prognosis of the same. Further prospective longitudinal studies are required to assess the salivary LDH levels among the patients with malignant transformation of Oral Potentially malignant lesions/conditions to oral cancers.PMID:38665466 | PMC:PMC11042121 | DOI:10.4103/ijcm.ijcm_612_22 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Kumuda Rao Subhas G Babu Shishir Ram Shetty Renita Lorina Castelino Source Type: research
Association between Toothbrushing and Cancer Risk
CONCLUSION: The findings of this study suggest that daily toothbrushing is essential for maintaining oral health and preventing cancer.PMID:38665324 | PMC:PMC11039440 | DOI:10.15280/jlm.2024.14.1.31 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Akifumi Enomoto Yuto Takada Takeshi Shimoide Atsushi-Doksa Lee Yuko Kinoshita Miku Kawaguchi Yasuhiro Kakiuchi Takahiro Tabuchi Source Type: research
Hangeshashinto Inhibits < em > Porphyromonas gingivalis < /em > Pathogen-Associated Molecular Patterns-Mediated IL-6 and IL-8 Production through Toll-Like Receptors in CAL27 Cells
This study suggests that the anti-inflammatory effects of hangeshashinto may be attributed to the inhibition of TLR signal transduction pathways including NF-κB activation, thereby suppressing NF-κB-dependent gene expression.PMID:38665937 | PMC:PMC11045287 | DOI:10.1155/2024/9866670 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - April 26, 2024 Category: Complementary Medicine Authors: Hourei Oh Yoshimasa Makita Kazuya Masuno Yasuhiro Imamura Source Type: research
Calcitriol Treatment Decreases Cell Migration, Viability and β-Catenin Signaling in Oral Dysplasia
Curr Issues Mol Biol. 2024 Apr 2;46(4):3050-3062. doi: 10.3390/cimb46040191.ABSTRACTNearly 90% of oral cancers are characterized as oral squamous cell carcinoma (OSCC), representing the sixth most common type of cancer. OSCC usually evolves from oral potentially malignant disorders that, in some cases, are histologically consistent with a oral dysplasia. The levels of 1α,25 dihydroxyvitamin D3 (1,25-(OH)2D3; calcitriol), the active form of vitamin D3, have been shown to be decreased in patients with oral dysplasia and OSCC. Moreover, treatment with 1,25-(OH)2D3 has been proven beneficial in OSCC by inhibiting the Wnt/β-c...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Daniel Pe ña-Oyarzún Constanza Guzm án Catalina Kretschmar Vicente A Torres Andrea Maturana-Ramirez Juan Aitken Montserrat Reyes Source Type: research
Frankincense ( < em > Boswellia serrata < /em > ) Extract Effects on Growth and Biofilm Formation of < em > Porphyromonas gingivalis < /em > , and Its Intracellular Infection in Human Gingival Epithelial Cells
Curr Issues Mol Biol. 2024 Mar 30;46(4):2991-3004. doi: 10.3390/cimb46040187.ABSTRACTFrankincense is produced by Boswellia trees, which can be found throughout the Middle East and parts of Africa and Asia. Boswellia serrata extract has been shown to have anti-cancer, anti-inflammatory, and antimicrobial effects. Periodontitis is an oral chronic inflammatory disease that affects nearly half of the US population. We investigated the antimicrobial effects of B. serrata extract on two oral pathogens associated with periodontitis. Using the minimum inhibitory concentration and crystal violet staining methods, we demonstrated th...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: David Vang Aline Cristina Abreu Moreira-Souza Nicholas Zusman German Moncada Harmony Matshik Dakafay Homer Asadi David M Ojcius Cassio Luiz Coutinho Almeida-da-Silva Source Type: research
Efficacy and safety of combined anlotinib-oral etoposide treatment for patients with platinum-resistant ovarian cancer
CONCLUSION: Anlotinib combined with etoposide emerged effective for the treatment of PROC.PMID:38670563 | DOI:10.3802/jgo.2024.35.e100 (Source: Journal of Gynecologic Oncology)
Source: Journal of Gynecologic Oncology - April 26, 2024 Category: OBGYN Authors: Shuai Huang Guihua Sheng Qiubo Lv Ye Li Qingwei Meng Xuexiao Gao Zhiyuan Shang Source Type: research
Calcitriol Treatment Decreases Cell Migration, Viability and beta-Catenin Signaling in Oral Dysplasia
Curr Issues Mol Biol. 2024 Apr 2;46(4):3050-3062. doi: 10.3390/cimb46040191.ABSTRACTNearly 90% of oral cancers are characterized as oral squamous cell carcinoma (OSCC), representing the sixth most common type of cancer. OSCC usually evolves from oral potentially malignant disorders that, in some cases, are histologically consistent with a oral dysplasia. The levels of 1α,25 dihydroxyvitamin D3 (1,25-(OH)2D3; calcitriol), the active form of vitamin D3, have been shown to be decreased in patients with oral dysplasia and OSCC. Moreover, treatment with 1,25-(OH)2D3 has been proven beneficial in OSCC by inhibiting the Wnt/β-c...
Source: Mol Biol Cell - April 26, 2024 Category: Molecular Biology Authors: Daniel Pe ña-Oyarzún Constanza Guzm án Catalina Kretschmar Vicente A Torres Andrea Maturana-Ramirez Juan Aitken Montserrat Reyes Source Type: research
Interdisciplinary Collaboration in Head and Neck Cancer Care: Optimizing Oral Health Management for Patients Undergoing Radiation Therapy
In conclusion, these proactive measures help minimize dental and oral complications before, during, and after treatment.PMID:38668058 | PMC:PMC11049200 | DOI:10.3390/curroncol31040155 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Tugce Kutuk Ece Atak Alessandro Villa Noah S Kalman Adeel Kaiser Source Type: research
The Efficiency and Toxicity Of Anlotinib in Combination With Docetaxel Followed by Epirubicin and Cyclophosphamide Regimen as Neoadjuvant Treatment in IIB to IIIA Triple Negative Breast Cancer: A Single-Arm, Multicenter, Open-Label, Phase II Study
CONCLUSION: The combination of anlotinib and EC-T chemotherapy demonstrated tolerable side effects in the neoadjuvant treatment of early TNBC. pCR was higher than what has been reported in previous clinical studies of chemotherapy alone. This study provides additional rationale for using anlotinib plus docetaxel-epirubicin-based chemotherapy regimen in patients with early-stage TNBCs.PMID:38670862 | DOI:10.1016/j.clbc.2024.01.018 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Xi Chen Xinyu Wei Peizhuo Yao Yanbin Liu Haitao Guan Huafeng Kang Di Liu Yan Diao Xiaobin Ma Weili Min Changyou Shan Yang Zhao Fang Zhao Yuanyuan Chen Dong Xiao Qing She Youhuai Liu Yinbin Zhang Shuqun Zhang Source Type: research
