Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Efficacy of novel oral anticoagulants in active cancer patients with venous thromboembolism protocol for an umbrella meta-analysis
Asian J Surg. 2024 Apr 26:S1015-9584(24)00538-4. doi: 10.1016/j.asjsur.2024.03.103. Online ahead of print.NO ABSTRACTPMID:38677928 | DOI:10.1016/j.asjsur.2024.03.103 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 27, 2024 Category: Surgery Authors: Haoyue Yang Yuwei Hu Hang Zhang Kai Wang Source Type: research
Inhibition of Human UDP-Glucuronosyltransferase Enzyme by Entrectinib: Implications for Drug-Drug Interactions
Chem Biol Interact. 2024 Apr 25:111023. doi: 10.1016/j.cbi.2024.111023. Online ahead of print.ABSTRACTAs a new type of oral tyrosine kinase inhibitor, entrectinib can act on multiple targets and exert efficacy and has been approved for the treatment of non-small cell lung cancer (NSCLC) and solid tumors. However, whether entrectinib affects the activities of recombinant human UDP-glucuronosyltransferases (UGTs) remains unclear. Herein, we aimed to investigate the inhibitory effects of entrectinib on human UGTs and to assess the potential risk of causing drug-drug interactions (DDIs) based on the inhibition against UGTs. Hi...
Source: Chemico-Biological Interactions - April 27, 2024 Category: Molecular Biology Authors: Hang Yin Zhe Wang Xin Lv Zhen Wang Ying Wang Wenxuan Fan Shuang Li Lili Jiang Jun Cao Yong Liu Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: Endocrine Reviews - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Efficacy of novel oral anticoagulants in active cancer patients with venous thromboembolism protocol for an umbrella meta-analysis
Asian J Surg. 2024 Apr 26:S1015-9584(24)00538-4. doi: 10.1016/j.asjsur.2024.03.103. Online ahead of print.NO ABSTRACTPMID:38677928 | DOI:10.1016/j.asjsur.2024.03.103 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 27, 2024 Category: Surgery Authors: Haoyue Yang Yuwei Hu Hang Zhang Kai Wang Source Type: research
High Twist expression can be an early event in lip carcinogenesis
ConclusionsThe results suggest that the high immunoexpression of Twist is an early lip carcinogenesis event. However, it appears not to influence the progression of ED in AC. (Source: Oral Surgery)
Source: Oral Surgery - April 27, 2024 Category: ENT & OMF Authors: Israel Leal Cavalcante,
Caio César da Silva Barros,
Hellen Bandeira de Pontes Santos,
Amanda Katarinny Goes Gonzaga,
Silvia Helena Barem Rabenhorst,
Roberta Barroso Cavalcante,
Éricka Janine Dantas da Silveira,
Ana Miryam Costa de Medeiros Tags: ORIGINAL ARTICLE Source Type: research
Cancers, Vol. 16, Pages 1696: Updates in Cancer Cachexia: Clinical Management and Pharmacologic Interventions
abbro
Despite a better understanding of the mechanisms causing cancer cachexia (CC) and development of promising pharmacologic and supportive care interventions, CC persists as an underdiagnosed and undertreated condition. CC contributes to fatigue, poor quality of life, functional impairment, increases treatment related toxicity, and reduces survival. The core elements of CC such as weight loss and poor appetite should be identified early. Currently, addressing contributing conditions (hypothyroidism, hypogonadism, and adrenal insufficiency), managing nutrition impact symptoms leading to decreased oral intake (nausea,...
Source: Cancers - April 27, 2024 Category: Cancer & Oncology Authors: Sudeep Pandey Lauren Bradley Egidio Del Fabbro Tags: Review Source Type: research
Cancers, Vol. 16, Pages 1704: Endoscopic Diagnosis of Small Bowel Tumor
oto
Recent technological advances, including capsule endoscopy (CE) and balloon-assisted endoscopy (BAE), have revealed that small intestinal disease is more common than previously thought. CE has advantages, including a high diagnostic yield, discomfort-free, outpatient basis, and physiological images. BAE enabled endoscopic diagnosis and treatment in the deep small bowel. Computed tomography (CT) enterography with negative oral contrast can evaluate masses, wall thickening, and narrowing of the small intestine. In addition, enhanced CT can detect abnormalities outside the gastrointestinal tract that endoscopy cannot ...
Source: Cancers - April 27, 2024 Category: Cancer & Oncology Authors: Tomonori Yano Hironori Yamamoto Tags: Review Source Type: research
Arenobufagin induces cell apoptosis by modulating the cell cycle regulator claspin and the JNK pathway in nasopharyngeal carcinoma cells
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 27, 2024 Category: Drugs & Pharmacology Authors: Hsin-Yu HoMu-Kuan ChenChia-Chieh LinYu-Sheng LoYi-Ching ChuangMing-Ju Hsieha Oral Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwanb Department of Otorhinolaryngology-Head and Neck Surgery, Changhua Christian Hospital, Changhua, Taiwan Source Type: research
Comparison of endoscopic thyroidectomy via the oral vestibule approach and the areola approach for papillary thyroid carcinoma
The endoscopic thyroidectomy areola approach (ETAA) has been widely applied for papillary thyroid carcinoma (PTC), but leaves scars and is not truly minimally invasive. The oral vestibular approach (ETOVA) lea... (Source: BMC Surgery)
Source: BMC Surgery - April 27, 2024 Category: Surgery Authors: Yingying Liu, Fusheng Lin, Wei Yan, Ende Lin, Penghao Kuang, Xiaoquan Hong, Yizhuo Lu, Guoyang Wu and Lianghui Li Tags: Research Source Type: research
Interdisciplinary Collaboration in Head and Neck Cancer Care: Optimizing Oral Health Management for Patients Undergoing Radiation Therapy
In conclusion, these proactive measures help minimize dental and oral complications before, during, and after treatment.PMID:38668058 | DOI:10.3390/curroncol31040155 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Tugce Kutuk Ece Atak Alessandro Villa Noah S Kalman Adeel Kaiser Source Type: research
Human papillomavirus infection: Epidemiology, biology, host interactions, cancer development, prevention, and therapeutics
This study aimed to carry out a literature review considering several aspects involving HPV infection: Global distribution, prevalence, biology, host interactions, cancer development, prevention, therapeutics, coinfection with other viruses, coinfection with bacteria, association with head and neck squamous cell carcinomas, and association with anal cancer.PMID:38666757 | DOI:10.1002/rmv.2537 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Jonas Wolf Lucas Felipe Kist Samanta Brangel Pereira Marilze Alves Quessada Helena Petek Arthur Pille Ju çara Gasparetto Maccari Mohamed Parrini Mutlaq Luiz Antonio Nasi Source Type: research
Evaluation of Serum and Salivary Lactate Dehydrogenase Levels in Patients with Oral Potentially Malignant Conditions/Lesions: A Clinical and Biochemical Study
CONCLUSION: Higher serum and salivary LDH levels in Oral Potentially malignant lesions/conditions than in control groups signifies the importance of assessing salivary LDH levels, in the prognosis of the same. Further prospective longitudinal studies are required to assess the salivary LDH levels among the patients with malignant transformation of Oral Potentially malignant lesions/conditions to oral cancers.PMID:38665466 | PMC:PMC11042121 | DOI:10.4103/ijcm.ijcm_612_22 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Kumuda Rao Subhas G Babu Shishir Ram Shetty Renita Lorina Castelino Source Type: research
Association between Toothbrushing and Cancer Risk
CONCLUSION: The findings of this study suggest that daily toothbrushing is essential for maintaining oral health and preventing cancer.PMID:38665324 | PMC:PMC11039440 | DOI:10.15280/jlm.2024.14.1.31 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Akifumi Enomoto Yuto Takada Takeshi Shimoide Atsushi-Doksa Lee Yuko Kinoshita Miku Kawaguchi Yasuhiro Kakiuchi Takahiro Tabuchi Source Type: research
