Taking the road less traveled – the therapeutic potential of CBP/β-catenin antagonists
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 27, 2021 Category: Drugs & Pharmacology Authors: Michael Kahn Source Type: research

Emerging roles of autophagy in the development and treatment of urothelial carcinoma of the bladder
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 27, 2021 Category: Drugs & Pharmacology Authors: Pratishtha Gupta Niraj Kumar Minal Garg Source Type: research

Implications of recent molecular achievements in early diagnosis and precision treatments for primary CNS lymphoma
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 26, 2021 Category: Drugs & Pharmacology Authors: Teresa Calimeri Sara Steffanoni Marco Foppoli Maurilio Ponzoni Andr és J. M. Ferreri Source Type: research

Therapeutic potential of PGC-1 α in age-related macular degeneration (AMD) – the involvement of mitochondrial quality control, autophagy, and antioxidant response
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 25, 2021 Category: Drugs & Pharmacology Authors: Juha Hyttinen Janusz Blasiak Pasi Tavi Kai Kaarniranta Source Type: research

Cellular senescence in liver fibrosis: Implications for age-related chronic liver diseases
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 22, 2021 Category: Drugs & Pharmacology Authors: Wanvisa Udomsinprasert Abhasnee Sobhonslidsuk Jiraphun Jittikoon Sittisak Honsawek Usa Chaikledkaew Source Type: research

Endothelial dysfunction: a therapeutic target in bacterial sepsis?
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 22, 2021 Category: Drugs & Pharmacology Authors: Jean-Louis Vincent Can Ince Peter Pickkers Source Type: research

Transglutaminase 2 as a therapeutic target for neurological conditions
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 15, 2021 Category: Drugs & Pharmacology Authors: Jeffrey W. Keillor Gail V.W. Johnson Source Type: research

Medulloblastoma: novel insights into emerging therapeutic targets
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - October 4, 2021 Category: Drugs & Pharmacology Authors: Shavali Shaik Shinji Maegawa Vidya Gopalakrishnan Source Type: research

The CB2 cannabinoid receptor as a therapeutic target in the central nervous system
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - September 23, 2021 Category: Drugs & Pharmacology Authors: David Caba ñero Elena Mart ín-García Rafael Maldonado Source Type: research

NTRK fusions in colorectal cancer: clinical meaning and future perspective
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - September 16, 2021 Category: Drugs & Pharmacology Authors: Margherita Ratti Giulia Grizzi Rodolfo Passalacqua Andrea Lampis Fabrizio Cereatti Roberto Grassia Jens Claus Hahne Source Type: research

Hypoplastic left heart syndrome (HLHS): molecular pathogenesis and emerging drug targets for cardiac repair and regeneration
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - September 15, 2021 Category: Drugs & Pharmacology Authors: Anthony T Bejjani Neil Wary Mingxia Gu Source Type: research

Hepatocellular carcinoma (HCC): the most promising therapeutic targets in the preclinical arena based on tumor biology characteristics
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - September 11, 2021 Category: Drugs & Pharmacology Authors: Haichuan Wang Xin Chen Diego F. Calvisi Source Type: research

Emerging therapeutic targets for gastric cancer from a host-Helicobacter pylori interaction perspective
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - September 1, 2021 Category: Drugs & Pharmacology Authors: Esmat Abdi Saeid Latifi-Navid Fatemeh Abedi Sarvestani Mohammad Hassan Esmailnejad Source Type: research

Axial spondyloarthritis: emerging drug targets
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - August 30, 2021 Category: Drugs & Pharmacology Authors: Bilade Cherqaoui Luiza M. Araujo Simon Glatigny Maxime Breban Source Type: research

Emerging therapeutic targets for narcolepsy
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - August 25, 2021 Category: Drugs & Pharmacology Authors: Marieke Vringer Birgitte Rahbek Kornum Source Type: research

Tackling retinal ganglion cell apoptosis in glaucoma: role of adenosine receptors
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - August 24, 2021 Category: Drugs & Pharmacology Authors: Puneet Agarwal Renu Agarwal Source Type: research

Redox-sensitive TRP channels: a promising pharmacological target in chemotherapy-induced peripheral neuropathy
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - August 19, 2021 Category: Drugs & Pharmacology Authors: Ramandeep Singh Pratik Adhya Shyam Sunder Sharma Source Type: research

lncRNAs: potential therapeutic targets and biomarkers for pancreatic cancer?
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - August 11, 2021 Category: Drugs & Pharmacology Authors: Marta Montes Luis Arnes Source Type: research

Therapeutic impact of thymoquninone to alleviate ischemic brain injury via Nrf2/HO-1 pathway
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - August 6, 2021 Category: Drugs & Pharmacology Authors: Nashwa Amin Xiaoxue Du Shijia Chen Qiannan Ren Azhar B. Hussien Benson O.A. Botchway Zhiying Hu Marong Fang Source Type: research

BRCA mutations in pancreatic cancer and progress in their targeting
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - July 31, 2021 Category: Drugs & Pharmacology Authors: Samer Alkassis Omid Yazdanpanah Philip Agop Philip Source Type: research

Enteroviruses and coronaviruses: similarities and therapeutic targets
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - July 29, 2021 Category: Drugs & Pharmacology Authors: Varpu Marjom äki Kerttu Kalander Maarit Hellman Perttu Permi Source Type: research

Neuromodulatory effects of SARS-CoV2 infection: Possible therapeutic targets
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - July 20, 2021 Category: Drugs & Pharmacology Authors: Sonali Kumar Ozasvi R Shanker Neeraj Kumari Manjari Tripathi P Sarat Chandra Aparna Banerjee Dixit Jyotirmoy Banerjee Source Type: research

Tumor-associated neutrophils: orchestrating cancer pathobiology and therapeutic resistance
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - July 16, 2021 Category: Drugs & Pharmacology Authors: Triet M. Bui Lenore K Yalom Ronen Sumagin Source Type: research

Drugs that offer the potential to reduce hospitalization and mortality from SARS-CoV-2 infection: The possible role of the sigma-1 receptor and autophagy
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - July 15, 2021 Category: Drugs & Pharmacology Authors: James Michael Brimson Mani Iyer Prasanth Dicson Sheeja Malar Sirikalaya Brimson Premrutai Thitilertdecha Tewin Tencomnao Source Type: research

Aberrations of DNA repair pathways in prostate cancer: a cornerstone of precision oncology
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - July 8, 2021 Category: Drugs & Pharmacology Authors: Stergios Boussios Elie Rassy Sidrah Shah Evangelia Ioannidou Matin Sheriff Nicholas Pavlidis Source Type: research

The role of the sigma-1 receptor in neuroprotection: Comment on Nrf-2 as a therapeutic target in ischemic stroke
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - July 8, 2021 Category: Drugs & Pharmacology Authors: Mani Iyer Prasanth Tewin Tencomnao James Michael Brimson Source Type: research

Defibrotide: potential for treating endothelial dysfunction related to viral and post-infectious syndromes
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 25, 2021 Category: Drugs & Pharmacology Authors: Edward Richardson David Garc ía-Bernal Eleonora Calabretta Rub én Jara Marta Palomo Rebecca M. Baron Gregory Yanik Jawed Fareed Israel Vlodavsky Massimo Iacobelli Maribel D íaz-Ricart Paul G. Richardson Carmelo Carlo-Stella Jose M. Moraleda Source Type: research

CD36 as a target for metabolic modulation therapy in cardiac disease
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 22, 2021 Category: Drugs & Pharmacology Authors: Jan F.C. Glatz Fang Wang Miranda Nabben Joost J.F.P. Luiken Source Type: research

Peripheral vascular disease: preclinical models and emerging therapeutic targeting of the vascular endothelial growth factor ligand-receptor system
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 17, 2021 Category: Drugs & Pharmacology Authors: Vijay Chaitanya Ganta Brian H. Annex Source Type: research

The emerging role of the sigma-1 receptor in autophagy: hand-in-hand targets for the treatment of Alzheimer ’s
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 17, 2021 Category: Drugs & Pharmacology Authors: Mani Iyer Prasanth Dicson Sheeja Malar Tewin Tencomnao James Michael Brimson Source Type: research

Guanylyl cyclase 2C (GUCY2C) in gastrointestinal cancers: recent innovations and therapeutic potential
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 15, 2021 Category: Drugs & Pharmacology Authors: Ariana A. Entezari Adam E. Snook Scott A. Waldman Source Type: research

MET alterations and their impact on the future of non-small cell lung cancer (NSCLC) targeted therapies
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 14, 2021 Category: Drugs & Pharmacology Authors: Matthew Lee Prantesh Jain Feng Wang Patrick C. Ma Alain Borczuk Balazs Halmos Source Type: research

CCR5 is a potential therapeutic target for cancer
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 14, 2021 Category: Drugs & Pharmacology Authors: Hossein Hemmatazad Martin D. Berger Source Type: research

Reversing T-cell exhaustion in immunotherapy: a review on current approaches and limitations
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 10, 2021 Category: Drugs & Pharmacology Authors: Yasser Tabana Tae Chul Moon Arno Siraki Shokrollah Elahi Khaled Barakat Source Type: research

Microglia as therapeutic targets after neurological injury: strategy for cell therapy
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - June 2, 2021 Category: Drugs & Pharmacology Authors: M. Collins Scott Supinder S. Bedi Scott D. Olson Candice M. Sears Charles S. Cox Source Type: research

Epigenetic regulation in Alzheimer ’s disease: is it a potential therapeutic target?
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - May 13, 2021 Category: Drugs & Pharmacology Authors: Fabio Copped è Source Type: research

Inhibition of MK2 kinase as a potential therapeutic target to control neuroinflammation in Alzheimer ’s disease
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - May 10, 2021 Category: Drugs & Pharmacology Authors: Shriyansh Srivastava Rohan Rajopadhye Mangaldeep Dey Rakesh Kumar Singh Source Type: research

Targeting citrullination in autoimmunity: insights learned from preclinical mouse models
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - May 4, 2021 Category: Drugs & Pharmacology Authors: Ylke Bruggeman Fernanda M.C. Sodr é Mijke Buitinga Chantal Mathieu Lut Overbergh Maria J.L. Kracht Source Type: research

TLR4 as a therapeutic target for respiratory and neurological complications of SARS-CoV-2
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 28, 2021 Category: Drugs & Pharmacology Authors: Dhriti Kaushik Ranjana Bhandari Anurag Kuhad Source Type: research

Targeting RUNX1 in acute myeloid leukemia: preclinical innovations and therapeutic implications
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 28, 2021 Category: Drugs & Pharmacology Authors: Fanny Gonzales Adeline Barth élémy Pauline Peyrouze Laur ène Fenwarth Claude Preudhomme Nicolas Duployez Meyling H. Cheok Source Type: research

Myelofibrosis: challenges for preclinical models and emerging therapeutic targets
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 19, 2021 Category: Drugs & Pharmacology Authors: Erika Morsia Naseema Gangat Source Type: research

Hepatitis B virus: promising drug targets and therapeutic implications
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 19, 2021 Category: Drugs & Pharmacology Authors: Mohube Betty Maepa Kristie Bloom Abdullah Ely Patrick Arbuthnot Source Type: research

Targeting neuroprotective functions of astrocytes in neuroimmune diseases
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 15, 2021 Category: Drugs & Pharmacology Authors: Andis Klegeris Source Type: research

Emerging therapeutic targets for sepsis
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 12, 2021 Category: Drugs & Pharmacology Authors: Elizabeth W. Tindal Brandon E. Armstead Sean F. Monaghan Daithi S. Heffernan Alfred Ayala Source Type: research

Targeting Fc effector function in vaccine design
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 7, 2021 Category: Drugs & Pharmacology Authors: Simone I. Richardson Penny L. Moore Source Type: research

Potassium channels as prominent targets and tools for the treatment of epilepsy
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 6, 2021 Category: Drugs & Pharmacology Authors: ES Nikitin LV Vinogradova Source Type: research

KRAS G12C inhibition and innate immune targeting
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - March 28, 2021 Category: Drugs & Pharmacology Authors: Tetsuo Tani Shunsuke Kitajima Ella B. Conway Erik H. Knelson David A. Barbie Source Type: research

Macrophage polarization: an effective approach to targeted therapy of inflammatory bowel disease
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - March 17, 2021 Category: Drugs & Pharmacology Authors: Yaoyao Du Lan Rong Yuanhua Cong Lan Shen Ning Zhang Bing Wang Source Type: research

The Nrf2 pathway in psychiatric disorders: pathophysiological role and potential targeting
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - March 14, 2021 Category: Drugs & Pharmacology Authors: Ranjana Bhandari Japneet Kaur Simerpreet Kaur Anurag Kuhad Source Type: research

Nrf2 as a therapeutic target in ischemic stroke
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - March 2, 2021 Category: Drugs & Pharmacology Authors: Alexandra Mazur Madison Fangman Rani Ashouri Arianna Arcenas Sylvain Dor é Source Type: research