Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome
Conditions: Squamous Cell Carcinoma of the Oral Cavity; Squamous Cell Carcinoma of the Oropharynx; Squamous Cell Carcinoma of the Hypopharynx; Squamous Cell Carcinoma of the Larynx Interventions: Other: data collection Sponsors: AIO-Studien-gGmbH; Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials
Alternative Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
Conditions: E-cigarette Use; Cigarette Smoking; Harm Reduction; Tobacco Use Interventions: Other: E-cigarettes; Other: Oral nicotine pouches Sponsors: University of Pennsylvania; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC.
Conditions: Triple-negative Breast Cancer Interventions: Drug: ATRA; Drug: Toripalimab Sponsors: First Affiliated Hospital of Zhejiang University; Shanghai Longfine Biotechnology Co., Ltd.; TopAlliance Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials
10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma
Conditions: HNSCC; AI; Radiomic; MRI Interventions: Diagnostic Test: The Resnet50 deep learning (DL) model Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials
Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours
Conditions: Advanced Cancer; Advanced Solid Tumor; Lymphoma, Hodgkin; Central Nervous System Tumor; Sarcoma; Germ Cell Tumor; Pediatric Cancer Interventions: Dietary Supplement: Ocoxin Oral solution Sponsors: Catalysis SL Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
Conditions: Advanced Cancer; Advanced Solid Tumor; Melanoma; Metastasis; Pleural Mesothelioma; Renal Cell Carcinoma; MSI-High; Mismatch Repair Deficiency; Colorectal Cancer; Hepatocellular Carcinoma; Hepatocellular Cancer; Renal Cell Cancer; Kidney Cancer; Skin Cancer; Non Small Cell Lung Cancer; NSCLC; Anaplastic Lymphoma Kinase Genomic Tumor Aberrations; ALK Genomic Tumor Aberrations Interventions: Drug: Alintegimod; Drug: Ipilimumab; Drug: Nivolumab Sponsors: 7 Hills Pharma, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer
Conditions: Oropharyngeal Squamous Cell Carcinoma; Human Papillomavirus Infection Interventions: Genetic: Pre-Radiation Dental Evaluation/Sample Collection; Other: Pre-Study Visit; Genetic: Oral Medicine Consultation Visit/Sample Collection Sponsors: Wake Forest University Health Sciences; InnoTech Precision Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
Pre-operative Immuno-Nutrition in Radical Cystectomy
Conditions: Bladder Cancer Interventions: Dietary Supplement: Immunonutrition; Dietary Supplement: Standard Oral Nutritional Supplement Sponsors: Fondazione IRCCS Policlinico San Matteo di Pavia; IRCCS Ospedale San Raffaele Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients.
Conditions: Oral Mucositis (Ulcerative) Due to Radiation Interventions: Drug: N-Acetyl-Cysteine with Institutional standard care; Drug: Institutional standard care Sponsors: Mansoura University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
IV Dexmedetomidine vs Oral Gabapentin and Their Combination for Postoperative Analgesia in Cancer Patients Undergoing Modified Radical Mastectomy
Conditions: Breast Cancer; Pain, Postoperative; Pain, Acute Interventions: Drug: Dexmedetomidine Hydrochloride 0.5 MG/ML; Drug: Gabapentin Sponsors: National Cancer Institute, Egypt Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
De-Escalation Postoperative Radiotherapy for Oral Squamous Cell Carcinoma With pCR/MPR.
Conditions: De-escalated Radiotherapy; Head and Neck Cancer Interventions: Radiation: Continuous, hyperfractionated, accelerated radiotherapy(CHART) Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients
Conditions: Cervical Cancers Interventions: Dietary Supplement: enteral immunonutrition; Dietary Supplement: standard oral enteral nutrition Sponsors: SHUANGZHENGJIA Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 5, 2024 Category: Research Source Type: clinical trials
Oral Inulin in Combination With Fruquintinib Plus Sintilimab as Third- or Further-line Treatment in Metastatic Colorectal Cancer
Conditions: Metastatic Colorectal Cancer Interventions: Drug: Fruquintinib; Drug: Sintilimab; Drug: Inulin Sponsors: Wuhan Union Hospital, China; Huazhong University of Science and Technology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials
Merck Initiates Phase 3 Clinical Trial of MK-1084, an Investigational Oral KRAS G12C Inhibitor, in Combination with Keytruda (pembrolizumab) for First-Line Treatment of Certain Patients With Metastatic Non-Small Cell Lung Cancer
RAHWAY, N.J.--(BUSINESS WIRE) April 4, 2024 -- Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced it has initiated a Phase 3 clinical trial evaluating MK-1084, an investigational oral selective KRAS G12C... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - April 4, 2024 Category: Pharmaceuticals Source Type: clinical trials
" Ultra-High Frequency intraOral UltraSonography of the TONgue " (HOUSTON)
Conditions: Oral Squamous Cell Carcinoma Interventions: Device: Ultrasound Sponsors: University of Pisa Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials
