Large study of thoracic aortic aneurysm backs guidelines
OAKLAND, Calif., Oct. 5, 2022. A large, new Kaiser Permanente study provides high-quality evidence that most of the 33,000 patients diagnosed each year in the U.S. with a thoracic aortic aneurysm— a bulge in the part of the main artery that... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 5, 2022 Category: Pharmaceuticals Source Type: clinical trials

Lumen Bioscience Announces Preclinical Data Demonstrating Needle Free, Spirulina-produced Vaccination Offering Protection Against Malaria
SEATTLE, Oct. 4, 2022. Lumen Bioscience, a clinical-stage biotechnology company developing biologic drugs for highly prevalent diseases, today announced the publication of data demonstrating a needle-free, spirulina-produced recombinant vaccine that... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 4, 2022 Category: Pharmaceuticals Source Type: clinical trials

NIH-Supported Clinical Trial of Phage Therapy for Cystic Fibrosis Begins
October 4, 2022 -- Enrollment has begun in an early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis (CF) who carry Pseudomonas aeruginosa (P. aeruginosa) in their lungs. The trial is evaluating whether the... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 4, 2022 Category: Pharmaceuticals Source Type: clinical trials

NIH DREAM Study Finds Viagra and Cialis Do Not Reduce Risk of Alzheimer ’s and Related Dementias
October 4, 2022 -- Results from the National Institutes of Health’s Drug Repurposing for Effective Alzheimer’s Medicines (DREAM) study show that sildenafil (Viagra) and tadalafil (Cialis) may not be suitable candidates for treating... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 4, 2022 Category: Pharmaceuticals Source Type: clinical trials

Biogen and Denali Therapeutics Announce Initiation of the Phase 3 LIGHTHOUSE Study in Parkinson ’s Disease Associated with LRRK2 Pathogenic Mutations
Global Phase 3 study to evaluate efficacy and safety of BIIB122, a small molecule inhibitor of LRRK2 LRRK2 mutations are one of the most common genetic drivers of Parkinson’s disease Targeting LRRK2 has the potential to impact the... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 3, 2022 Category: Pharmaceuticals Source Type: clinical trials

REGENXBIO Announces Additional Positive Interim Data from Trials of RGX-314 for the Treatment of Wet AMD
ROCKVILLE, Md, Oct. 3, 2022. REGENXBIO Inc. today announced a program update from its ongoing clinical investigation of RGX-314 for the treatment of wet AMD, a leading cause of vision loss globally. REGENXBIO announced positive interim data from... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 3, 2022 Category: Pharmaceuticals Source Type: clinical trials

Poxel Announces PXL770 Granted Orphan Drug Designation from the U.S. FDA for Autosomal-Dominant Polycystic Kidney Disease (ADPKD)
Completion of preclinical studies support potential to advance PXL770 into Phase 2 development for ADPKD Compelling preclinical efficacy data confirm strategic focus for PXL770 in rare metabolic diseases LYON, France--... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 3, 2022 Category: Pharmaceuticals Source Type: clinical trials

Calithera Receives FDA Fast Track Designation for Sapanisertib for the Treatment of NRF2-mutated Squamous Lung Cancer
Enrollment ongoing in Phase 2 study evaluating sapanisertib, a dual mTORC1/2 inhibitor, in patients with squamous non-small cell lung cancer harboring a NRF2 mutation SOUTH SAN FRANCISCO, Calif., Oct. 03, 2022 (GLOBE NEWSWIRE) -- Calithera... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 3, 2022 Category: Pharmaceuticals Source Type: clinical trials

A New Urine Test Could Help Curtail the Use of the Latest Synthetic Cannabinoids to Enter the Drug Scene
WASHINGTON, Sept. 30, 2022. A first-of-its-kind study published today in AACC ' s Clinical Chemistry journal shows that a novel drug test detects a new class of synthetic cannabinoids called OXIZIDs. This test could enable drug enforcement agencies to... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 30, 2022 Category: Pharmaceuticals Source Type: clinical trials

FDA Approves New Treatment Option for Patients with ALS
SILVER SPRING, Md., Sept. 29, 2022. The U.S. Food and Drug Administration today approved Relyvrio (sodium phenylbutyrate/taurursodiol) to treat patients with amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig ' s disease. " This... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 29, 2022 Category: Pharmaceuticals Source Type: clinical trials

Mallinckrodt Announces Submission of 510(k) to the U.S. FDA for Inhaled Nitric Oxide Delivery System
DUBLIN, Sept. 28, 2022 /PRNewswire/ -- Mallinckrodt plc (OTCMKTS: MNKPF), a global specialty pharmaceutical company, today announced the submission of a 510(k) premarket notification application to the U.S. Food and Drug Administration... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 28, 2022 Category: Pharmaceuticals Source Type: clinical trials

Pharming Announces US FDA Acceptance for Priority Review of its New Drug Application for Leniolisib
LEIDEN, The Netherlands, Sept. 28, 2022.Pharming Group N.V. ( " Pharming " or " the Company " ) announces that the US Food and Drug Administration (FDA) has accepted for priority review its New Drug Application (NDA) for leniolisib, an oral, selective... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 28, 2022 Category: Pharmaceuticals Source Type: clinical trials

Bionic Pancreas Improves Type 1 Diabetes Management Compared to Standard Insulin Delivery Methods
September 28, 2022 -- A device known as a bionic pancreas, which uses next-generation technology to automatically deliver insulin, was more effective at maintaining blood glucose (sugar) levels within normal range than standard-of-care management... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 28, 2022 Category: Pharmaceuticals Source Type: clinical trials

NIH Initiative to Systematically Investigate and Establish Function of Every Human Gene
September 27, 2022 -- The National Institutes of Health is launching a program to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene. The Molecular... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 27, 2022 Category: Pharmaceuticals Source Type: clinical trials

Study Confirms Link Between COVID-19 Vaccination and Temporary Increase in Menstrual Cycle Length
September 27, 2022 -- A large international study has confirmed the findings of a previous U.S. study that linked COVID-19 vaccination with an average increase in menstrual cycle length of less than one day. The increase was not associated with any... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 27, 2022 Category: Pharmaceuticals Source Type: clinical trials