Validity of Viome's Oral/Throat Cancer Test
Conditions: Oral and Throat Cancer; Oropharyngeal Squamous Cell Carcinoma; Oral Squamous Cell Carcinoma Interventions: Device: Oral/Throat cancer test Sponsors: Viome Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 18, 2023 Category: Research Source Type: clinical trials
Induction of double-strand breaks with the non-steroidal androgen receptor ligand flutamide in patients on androgen suppression: a study protocol for a randomized, double-blind prospective trial
This study will confirm in humans the pharmacodynamic effect of AR ligands to induce transient double-strand breaks when administered in the context of androgen deprivation as a novel therapy for prostate cancer. The findings of this study will permit the development of a larger trial evaluating flutamide pulsed-dose sequencing in association with fractionated external beam RT (+/ − brachytherapy). The study is ongoing, and preliminary data collection and recruitment are underway; analysis has yet to be performed.Trial registrationClinicalTrials.gov NCT03507608. Prospectively registered on 25 April 2018. (Source: Trials)
Source: Trials - December 16, 2023 Category: Research Source Type: clinical trials
Circulating Tumor DNA Guided Adjuvant Chemotherapy for Biliary Tract Carcinoma
Conditions: Biliary Tract Cancer Interventions: Drug: S-1(Intravenous combined with oral) Sponsors: Shanghai East Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials
Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study
Conditions: Tongue Neoplasms Interventions: Procedure: removal of primary tumor, neck dissection Sponsors: Cairo University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials
Consumer Responses to Alcohol Warnings
Conditions: Alcohol Drinking Interventions: Behavioral: Mouth cancer warning; Behavioral: Throat cancer warning; Behavioral: Voice box (larynx) warning; Behavioral: Esophagus cancer warning; Behavioral: Liver cancer warning; Behavioral: Colon and rectum cancer warning; Behavioral: Breast cancer; Behavioral: Cancer (generic, not site-specific); Behavioral: Addiction and neurological changes; Behavioral: Hypertension; Behavioral: Liver damage; Behavioral: Harm to fetus; Behavioral: Dementia; Behavioral: Impaired sleep; Behavioral: Drinking guidelines; Behavioral: Control; Behavioral: Road injuries Sponsors: Stanford Universi...
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials
Pembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma
Conditions: Relapsed Peripheral T-Cell Lymphoma; Refractory Peripheral T-Cell Lymphoma Interventions: Drug: Pembrolizumab IV infusion Q3W, with daily oral Olaparib. Sponsors: National Cancer Centre, Singapore; Merck Sharp& Dohme LLC; National Medical Research Council (NMRC), Singapore Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials
A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients
Conditions: Metastatic Castration-resistant Prostate Cancer Interventions: Drug: HP518 - Dose Escalation; Drug: HP518 - Dose Escalation; Drug: HP518 -Dose Expansion Sponsors: Hinova Pharmaceuticals Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2023 Category: Research Source Type: clinical trials
A prospective, single-centre, randomized, double-blind controlled study protocol to study whether long-term oral metronidazole can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer
This study is a prospective, single-centre, randomized, double-blind controlled study in which 300 patients will be randomly assigned to the test group or the control group in a 1:1 allocation ratio. The aim of this trial is to demonstrate that long-term oral antibiotics can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer.Ethics and disseminationEthics approval was obtained from the Ethics Committee at the Chinese Ethics Committee of Registering Clinical Trials (ChiECRCT20210229). The results of this study will be disseminated at several research conferences and as publ...
Source: Trials - December 4, 2023 Category: Research Source Type: clinical trials
Evaluate the Meritup Oral Solution to Decrease Fatigue in Metastatic Breast Cancer Patients Receiving Chemotherapy
Conditions: Metastatic Breast Cancer Interventions: Combination Product: Meritup oral solution Sponsors: Chung Shan Medical University; Phytofound Biotech Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 30, 2023 Category: Research Source Type: clinical trials
Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)
Conditions: Early-stage Breast Cancer; Estrogen-receptor-positive Breast Cancer Interventions: Procedure: Prospective data and sample collection; Drug: Ketorolac 10 Mg Oral Tablet; Drug: Pregabalin 75mg Sponsors: Jules Bordet Institute; KU Leuven; University of Milan Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 29, 2023 Category: Research Source Type: clinical trials
Antibiotics and Vaccine Immune Responses Study
Conditions: Vaccine Response Impaired Interventions: Biological: BCG vaccine; Biological: Yellow Fever vaccine; Drug: Vancomycin Oral Capsule; Drug: Neomycin Oral Product Sponsors: South Australian Health and Medical Research Institute; Royal Adelaide Hospital; Flinders University; University of Sydney; Telethon Kids Institute; Centenary Institute of Cancer Medicine and Cell Biology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials
Manual Therapy for Oral Health on Head and Neck Cancer Survivors
Conditions: Head and Neck Cancer; Trismus; Dysfunction Interventions: Other: Manual Therapy; Other: Control motor exercises Sponsors: Universidad de La Frontera Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials
A Phase 1a " Window Trial " On Cannabidiol (CBD) For Breast Cancer Primary Tumors
Conditions: Breast Cancer Interventions: Drug: CBD Oral; Other: Control Sponsors: Medical University of South Carolina Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials
Response to Neoadjuvant Chemoimmunotherapy in Resectable Locally Advanced Oral Cancer
Conditions: Oral Cancer Interventions: Drug: PD-1 inhibitor+carboplatin+albumin-bound paclitaxel Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors
Conditions: Triple Negative Breast Cancer; High Grade Serous Ovarian Cancer; Endometrial Cancer Interventions: Drug: AO-252 Sponsors: A2A Pharmaceuticals Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 17, 2023 Category: Research Source Type: clinical trials
