Neoadjuvant Tirellizumab Combined With Chemotherapy for Early Oral Squamous Cell Carcinoma(HNC-SYSU-004)
Conditions: Oral Cancer; PD-1 Interventions: Drug: PD-1 with chemotherapy; Procedure: upright surgery Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 14, 2023 Category: Research Source Type: clinical trials
Evaluations of Alcohol Warning Labels
Conditions: Oral Cancer; Esophageal Cancer; Larynx Cancer; Alcohol Drinking Interventions: Behavioral: Narrative pictorial warning labels for alcoholic beverages; Behavioral: Non-narrative pictorial warning labels for alcoholic beverages Sponsors: University of Connecticut; Oakland University; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
Study of Oral JYP0322 in Patients With Locally Advanced or Metastatic Cancer Targeting ROS1 Molecular Fusion.
Conditions: Protein Kinase Inhibitors; Other Protocol Specified Criteria; Lung Neoplasms; Brain Neoplasms Interventions: Drug: JYP0322 Sponsors: Guangzhou JOYO Pharma Co., Ltd Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
A Prospective, Single-arm Phase II Clinical Trial of Tislelizumab Combined With Platinum Doublet Neoadjuvant Therapy to Improve Mandibular Preservation in Resectable Locally Advanced Oral Squamous Cell Carcinoma.
Conditions: Oral Squamous Cell Carcinoma Interventions: Drug: Three-Week Treatment Regimen with Trastuzumab in Combination with Docetaxel and Platinum Triple Therapy Sponsors: Xuekui Liu Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients —efficacy and microbiologic safety
DiscussionThis trial will provide evidence of the efficacy of an alternative drug to ciprofloxacin for febrile neutropenia prevention in high-risk hematological patients. The battery of planned microbiological studies will allow us to evaluate prospectively the microbiological safety of both pharmacological strategies in terms of the selection of MRGNB occurring in each arm. In addition, valuable information on the way in which each drug changes the fecal microbiome of the patients throughout the treatment will be generated.Trial registrationClinical trials NCT05311254, Registered on 5 April 2022,https://clinicaltrials.gov...
Source: Trials - October 27, 2023 Category: Research Source Type: clinical trials
Progesterone Therapeutic Regimen Plus Statins in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia
Conditions: Atypical Endometrial Hyperplasia and Endometrial Carcinoma Stage I Interventions: Drug: statins (oral atorvastatin calcium tablet 20mg/ day; Or rosuvastatin 5mg/ day; Or pivastatin 2mg/ day); Sponsors: Peking University People ' s Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials
Prophylactic Oral Vitamin D and Zinc for Radiation-Induced Oral Mucositis in Head and Neck Cancer
Conditions: Oncology Interventions: Drug: Vitamin D Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 25, 2023 Category: Research Source Type: clinical trials
Nisin in Oral Cavity Squamous Cell Carcinoma (OCSCC)
Conditions: Oral Cavity Squamous Cell Carcinoma Interventions: Drug: NisinZ ® P; Procedure: Surgery (non-interventional, standard of care) Sponsors: University of California, San Francisco; University of California, Los Angeles; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 24, 2023 Category: Research Source Type: clinical trials
Tobacco and Alcohol Influence on Oncogenic Drivers and Somatic Evolution in the Oral Mucosa
Conditions: Carcinoma, Squamous Cell Interventions: Other: Oral cytobrush Sponsors: Hospices Civils de Lyon Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials
A Window of Opportunity Study of Black Raspberry for Patients With HNSCC
Conditions: Squamous Cell Carcinoma of the Oral Cavity or Oropharynx Interventions: Drug: Black Raspberry Sponsors: Mitchell Machtay Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant Lesions
Conditions: Oral Premalignant Lesions as Leukoplakia and Lichen Planus; Oral Cancer Interventions: Diagnostic Test: serum and unstimulated salivary samples Sponsors: Fayoum University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
BRE-08: A Phase II Study of an All-Oral Adjuvant Chemotherapy Regimen of Cyclophosphamide, Methotrexate, and Capecitabine (CMC) for Early-Stage Breast Cancer
Conditions: Breast Cancer Interventions: Drug: Cyclophosphamide; Drug: Methotrexate; Drug: Capecitabine Sponsors: University of Illinois at Chicago Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
HN-BIO: A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers
Conditions: Squamous Cell Carcinoma of Head and Neck Interventions: Other: fMRI; Other: Oral Pimonidazole Sponsors: University Health Network, Toronto Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
Conditions: Post-mastectomy Pain Syndrome Interventions: Drug: Duloxetine and magnesium sulphate; Drug: Duloxetine; Drug: placebo Sponsors: National Cancer Institute, Egypt Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
Conditions: Head and Neck Squamous Cell Carcinoma; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma; Oral Cavity Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Lip and Oral Cavity Cancer AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Or...
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials
