On the relationship between various anticoagulants and robot-assisted radical prostatectomy: a single-surgeon serial analysis
This study aims to explore the safety of robot-assisted prostatectomy in anticoagulated patients, without any exclusion criteria. The study included 500 patients who underwent RARP by a single surgeon between April 2019 and August 2022. Patients were divided into two groups: Group 1, consisting of 376 men (75.2%), did not receive any anticoagulation, while Group 2, with 124 patients (24.8%), received different forms of anticoagulation. Then, the anticoagulation group was divided into 4 subgroups according to their definite anticoagulation: the aspirin 15.6%, new oral anticoagulants (NOAC) 5.4%, Vitamin K antagonist (VKA) 2...
Source: Journal of Robotic Surgery - April 13, 2024 Category: Surgery Source Type: research
Genome-Wide Characterization of the Mutational Landscape of Proliferative Verrucous Leukoplakia.
Proliferative verrucous leukoplakia (PVL) is a rare but highly aggressive variant of oral leukoplakia that almost inevitably progresses to oral squamous cell carcinoma (OSCC). The aims of this study were to perform whole exome sequencing of a cohort of patients diagnosed with PVL and identify potential mutational profiles and pathways in this disorder. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 13, 2024 Category: ENT & OMF Authors: Camile S Farah, Kate Shearston, Phillip E Melton, Simon A Fox Source Type: research
Relationship between aggressive features of oral squamous cell carcinoma and the immunoexpression of CX3CR1, CX3CL1 and ITGAV.
: We aimed to describe the association between CX3CR1, CX3CL1 and ITGAV immunoexpression with PNI and adverse oncological outcomes in OSCC patients. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 13, 2024 Category: ENT & OMF Authors: Ren é Martínez-Flores, Carlo Lozano-Burgos, Sven Eric Niklander, Michelle Fernández-Cuya, Márcio Ajudarte Lopes, Wilfredo Alejandro González-Arriagada Source Type: research
MAML2-Rearrranged Sclerosing Mucoepidermoid Carcinoma of Submandibular Gland: An Incidental Finding in a Patient with History of Recurrent Sialadenitis and Sj ögren's syndrome
We present a new case of sclerosing mucoepidermoid carcinoma (SMEC) with MAML2 rearrangements. A 49-year-old woman with Sj ögren's syndrome experienced recurrent submandibular sialadenitis and sialolithiasis, leading to the removal of her right gland. Postoperative imaging revealed a calcified mass in her left gland which was subsequently resected. The pathological examination revealed a well-defined tumor with extensi ve fibrous stroma, predominantly epidermoid cells, and occasional mucinous components. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 13, 2024 Category: ENT & OMF Authors: Hasanain Hasan, Dinh Quoc Duong, Orly Coblens, Suimin Qiu, Cecilia G. Clement Source Type: research
Effect of Methanol and Ethyl Acetate Leaf Extracts of Osbeckia octandra L. (Heen Bovitiya) on the Apoptosis and Migration of Human Oral Squamous Cell Carcinoma Cell Lines
ConclusionThe results of this study depict the methanol and ethyl acetate extracts ofO. octandra possess anticancer activities on OSCC cells probably viaBCL2 pathway. Further in-depth studies are warranted to examine the exact bio-active compounds and the underneath mechanisms. (Source: Journal of Maxillofacial and Oral Surgery)
Source: Journal of Maxillofacial and Oral Surgery - April 13, 2024 Category: ENT & OMF Source Type: research
