Actinomycosis of the ventral tongue with successful laser ablation therapy: A case report
We present a first case report of an Actinomycosis lesion of the ventral tongue. Actinomycosis of the tongue is an uncommon finding. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 28, 2021 Category: ENT & OMF Authors: Andre Farquharson, Claudia C. Cotca, Alan Helig, Ronald S. Brown Source Type: research

Table of Contents
(Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 27, 2021 Category: ENT & OMF Source Type: research

Editorial Board
(Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 27, 2021 Category: ENT & OMF Source Type: research

Use of a combination of N-acetylcysteine and clonazepam to treat burning mouth syndrome
This study was intended to evaluate the clinical efficacy of a combination of N-acetylcysteine (NAC) and clonazepam for treatment of burning mouth syndrome (BMS). (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 24, 2021 Category: ENT & OMF Authors: Sungjun Han, Ji-Hyung Lim, Jooin Bang, Jung-Hae Cho Source Type: research

Orthokeratinized odontogenic cyst: a large series and comprehensive literature review with emphasis on synchronous multiple occurrence and neoplastic transformation
: To demonstrate the clinical, radiological, and histological features of orthokeratinized odontogenic cyst (OOC), determine the characteristics of multiple OOCs, and present rare but significant manifestations of OOC. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 21, 2021 Category: ENT & OMF Authors: Kyu-Young Oh, Jo-Eun Kim, Sung-Dae Cho, Hye-Jung Yoon, Jae-Il Lee, Seong-Doo Hong Tags: Original Article Source Type: research

Demographic, cardiological, microbiological, and dental profiles of brazilian patients who developed oral bacteria-related endocarditis
Infective endocarditis (IE) may cause devastating complications with high morbidity and mortality rates. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 20, 2021 Category: ENT & OMF Authors: T ânia Cristina Pedroso Montano, Marcelo Ivander Andrade Wanderley, Roney Orismar Sampaio, Carolina Guimarães Bonfim Alves, Itamara Lúcia Itagiba Neves, Marcio Ajudarte Lopes, Flavio Tarasoutchi, Tânia Mara Varejão Strabelli, Ricardo Simões Neves, M Source Type: research

2021 ACOMS Elaine A. Stuebner Scholars Award Winning Essay
The COVID-19 pandemic has changed life as we know it. The “new normal” has become a catch phrase to describe the many adaptations individuals and institutions have had to make in their lives due to the pandemic. As oral and maxillofacial surgeons, the new normal is a concept we know well. We have had to adjust to a new normal at every stage of our care er to be successful: during graduate school, residency/fellowship training, and our everyday practice. Each of these phases in our lives has required adjustment in our lifestyles and priorities, a tremendous amount of dedication and personal sacrifice. (Source: O...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 20, 2021 Category: ENT & OMF Authors: Caitlin B.L. Magraw Tags: Essay Source Type: research

Diagnostic utility of p63/p40 in the histological differentiation of salivary gland tumors: a systematic review
: Salivary gland tumors are heterogeneous group of neoplasms with complex clinicopathological behavior. These tumors often show an extremely diverse morphology and significant histological patterns making the diagnosis a difficult task. Due to the considerable differences in prognosis, treatment, and follow up, accurately distinguishing these histological mimickers is imperative. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 20, 2021 Category: ENT & OMF Authors: N Sivakumar, Anjali Narwal, Deepak Pandiar, Anju Devi, Rahul Anand, Deepty Bansal, Mala Kamboj Tags: Systematic review Source Type: research

Algorithm mediated early detection of Oral cancer from image analysis
To develop Automatic Oral Cancer Detection algorithm for identification and differentiation of premalignant lesions from buccal cavity images for early detection of oral cancer which reduce fatality in developing countries. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 20, 2021 Category: ENT & OMF Authors: Prachi Shah, Nilanjan Roy, Pinakin Dhandhukia Tags: Original Article Source Type: research

Expression of miRNA 21 in saliva & tumor tissue of Oral squamous cell carcinoma patients- A predictor of cervical lymph node metastasis.
Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, with more than 3,00,000 new cases reported world wide annually.1 OSCC is known to spread through lymphatics and about 40% patients present with metastasis to cervical lymph nodes. In presence of ipsilateral lymph node metastasis, the 5 year survival rate decreases by 50% in OSCC patients, as compared to those who do not have lymph node metastasis.2-4 (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 20, 2021 Category: ENT & OMF Authors: Kiran B. Jadhav, Vandana Shah, Nirali Chauhan, Naveen Shah, Ghanshyam Parmar Tags: Original research article Source Type: research

LINC01123 is associated with prognosis of oral squamous cell carcinoma and involved in tumor progression by sponging miR-34a-5p
This study aimed to investigate the role of a long non-coding RNA (lncRNA) LINC01123 in OSCC prognosis and progression, and explore the underlying mechanisms. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 20, 2021 Category: ENT & OMF Authors: Huan Qin, Changlei Wang, Yingjie Hua Tags: Original Article Source Type: research

Intratumoral lymphatic vascular density is an independent factor for disease-free and overall survival in advanced stage oral squamous cell carcinoma
This study aimed to evaluate the correlation between the lymphatic and blood vessels densities with prognostic outcomes in advanced stage OSCC. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 20, 2021 Category: ENT & OMF Authors: Juscelino Freitas Jardim, Marisol Miranda Galvis, Ivete Rodrigues Fabelo, Fernando Augusto Soares, Cl óvis Antônio Lopes Pinto, Luiz Paulo Kowalski Tags: Original Article Source Type: research

Stevens-Johnson syndrome Post Second Dose Pfizer COVID-19 Vaccine: A case report
We report one potential complication of the Pfizer COVID-19 vaccine; a known case of Stevens-Johnson syndrome (SJS) that occurred after the second dose of the Pfizer-COVID vaccine alone without exposure to any other drug. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 18, 2021 Category: ENT & OMF Authors: Mohamed Elboraey, Emad Al Sayed Faheem Essa Source Type: research

Ultrasonographic Evaluation of Edentulous Crestal Bone Topography: A Proof-of-Principle Retrospective Study
: Edentulous crestal bone ridge assessment, an essential task for planning of implant and bone regenerative procedures, is performed through radiographs. Ultrasonography, providing point-of-care, and cross-sectional images without radiation, could be an adjunct for this purpose. The aim was to investigate the feasibility of ultrasound (US) in assessing bone ridge width (BRW) and crestal bone surface quality (CBSQ) compared to Cone Beam Computed Tomography (CBCT). (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 18, 2021 Category: ENT & OMF Authors: Khaled Sinjab, Oliver D. Kripfgans, Alice Ou, Hsun-Liang Chan Source Type: research

Are incisional biopsies reliable for selecting definitive treatment of ameloblastomas? A 15-year interdisciplinary retrospective study.
Sampling error in incisional biopsy can lead to under/overtreatment. Aim of this study is to determine incidence of sampling error/discordance between incisional biopsy and final diagnosis and consequences on treatment outcomes. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 18, 2021 Category: ENT & OMF Authors: Shravan Kumar Renapurkar, Peter Broccoli, Caroline Carrico, Sarah Glass Source Type: research

Loss of FANCD2 and related proteins may predict malignant transformation in oral epithelial dysplasia
Predicting malignant transformation in oral epithelial dysplasia(OED) is challenging. The higher rate of malignant transformation (MT) reported in non-smokers suggests an endogenous etiology in oncogenesis. We hypothesize that loss of FANCD2 and associated proteins could influence genomic instability and MT in the absence of environmental carcinogens. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 16, 2021 Category: ENT & OMF Authors: Michael W Ho, Mark P Ryan, Juhi Gupta, Asterios Triantafyllou, Janet M Risk, Richard J Shaw, James B Wilson Source Type: research

A Clinical Study of Submandibular Schwannoma
Schwannoma is a slowly growing benign neurogenic tumor that develops from the cells of the nerve sheath. The occurrence of schwannoma in the submandibular space is very rare. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 16, 2021 Category: ENT & OMF Authors: Keon Woo Park, Dong Hoon Lee, Joon Kyoo Lee, Sang Chul Lim Source Type: research

Comparison of the diagnostic efficacy of 2-dimensional radiography and cone beam computed tomography in persistent apical periodontal disease: a PRISMA-DTA systematic review and Meta-analysis.
The objective was to answer the question: Do conventional radiographs (periapical/panoramic) afford better diagnostic outcomes than cone beam computed tomography (CBCT) as a complement for clinical diagnosis of apical lesions with persistent apical periodontitis or disease after root canal treatment? (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 14, 2021 Category: ENT & OMF Authors: Amparo Ramis-Alario, David Soto-Pe ñaloza, Beatriz Tarazona-Alvarez, Miguel Peñarrocha-Diago, David Peñarrocha-Oltra Tags: Review Article Source Type: research

Benign fibrous histiocytoma of the oral and maxillofacial region: a systematic review
: The aim of the present study was to carry out a systematic review of available data regarding case reports and case series of oral and maxillofacial benign fibrous histiocytoma (BFH). (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 14, 2021 Category: ENT & OMF Authors: Laura Borges Kirschnick, Lauren Frenzel Schuch, Felipe Martins Silveira, Bruna Barcelos S ó, Marco Antonio Trevizani Martins, Márcio Ajudarte Lopes, Pablo Agustin Vargas, Alan Roger Santos-Silva, Vinicius Coelho Carrard, Ana Carolina Uchoa Vasconcelos, Source Type: research

Central Odontogenic Fibroma in Association with Brown Tumor of Hyperparathyroidism in a Patient with NF1
We present a patient with bone abnormalities and a myriad of lesions secondary to his redeveloping renal failure and neurofibromatosis type 1. A 21-year-old male renal transplant recipient with NF1 presented with painless masses and large, irregular radiolucent lesions in the maxilla and mandible. Following histological examination, the lesion was diagnosed as a central odontogenic fibroma (COdF) in association with a central giant cell lesion, most consistent with brown tumor of hyperparathyroidism. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 14, 2021 Category: ENT & OMF Authors: Lauren A. Ruddocks, Alessandra F. Nascimento, Indraneel Bhattacharyya, Mohammed N. Islam, Donald. M. Cohen Tags: Case Report Source Type: research

Arthrocentesis versus nonsurgical methods in the management of temporomandibular joint closed lock and pain. A double-blind randomized controlled trial
The present double-blinded randomized clinical trial aimed to compare the efficacy of conservative treatment and articular lavage, either alone or combined with each other, to reduce joint pain and improve mandibular opening. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 10, 2021 Category: ENT & OMF Authors: Fabio G Ritto, Alexander Pomares Cueto, Jo ão Vitor dos Santos Canellas, John R Zuniga, Paul S. Tiwana, Thais Pimentel, Paulo Jose Medeiros Tags: Original Article Source Type: research

Impact of Radiation on Tooth Loss of Head and Neck Cancer Patients: A Retrospective Dosimetric-based Study
To characterize the dental adverse events following head and neck radiation therapy (HNRT) and to investigate the impact of regional radiation dose upon tooth loss outcomes. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 10, 2021 Category: ENT & OMF Authors: Wagner Gomes-Silva, Karina Morais-Faria, C ésar Rivera, Gabriel Faria Najas, Gustavo Nader Marta, Karina Gondim Moutinho da Conceição Vasconcelos, Heloisa de Andrade Carvalho, Gilberto de Castro, Thaís Bianca Brandão, Joel B. Epstein, Alan Roger Sant Tags: Original Article Source Type: research

Evaluating the use of anterolateral thigh flaps to prevent reconstruction plate exposure in patients with oral cancer
: Plate exposure remains one of the most serious complications of oromandibular reconstruction. The purpose of this study was to investigate the effect of wrapping reconstruction plates with anterolateral thigh (ALT) free flaps as a way to prevent plate exposure. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 5, 2021 Category: ENT & OMF Authors: Kun Wu, Sainan Li, Hanjiang Wu, Sheng Zhang Tags: Original Article Source Type: research

Gastrointestinal Stromal Tumor with Maxillary Metastasis: A Case Report and Literature Review
This report describes a unique case of a 77-year-old man who was diagnosed with duodenal GIST that was completely resected 15 years ago. Eleven years after complete resection, he presented with liver metastases and went on to receive multiple lines of systemic therapy and ablative radiotherapy. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 3, 2021 Category: ENT & OMF Authors: Ola M Maria, Ossama Alghamdi, Razan Baabdullah, Michel El-Hakim, Hani Al-Halabi, Nicholas M Makhoul Tags: Case Report Source Type: research

What do the aftermath of the 2010 Haiti earthquake, Hurricane Sandy, the Boston Marathon bombings, the 2013 Ebola outbreak and the COVID-19 pandemic, have in common?
Undoubtably, as the SARS-CoV-2 virus, responsible for the COVID-19 pandemic, spread across the world, information shared on social media “spread” with it. This “infodemic”, overabundance of information, commonly occurs during an epidemic and spreads between humans via various information systems1. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 1, 2021 Category: ENT & OMF Authors: Antonia Kolokythas Source Type: research

Bone formation following surgically assisted rapid maxillary expansion: comparison between two distraction osteogenesis protocols
: The aim of this study was to compare bone formation between two distraction osteogenesis protocols by analyzing cone-beam computed tomography (CBCT) scan data. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 26, 2021 Category: ENT & OMF Authors: Daniel Holzinger, Pedro Henrique de Azambuja Carvalho, Jos é Cleveilton dos Santos, Florian Wagner, Marisa Aparecida Cabrini Gabrielli, Mario Francisco Real Gabrielli, Valfrido Antonio Pereira Filho Tags: Original Article Source Type: research

Gray values of the cervical vertebrae detected by cone-beam computed tomography for the identification of osteoporosis and osteopenia in postmenopausal women
This study aimed to determine whether the gray values (GVs) of the second and third cervical vertebrae in cone-beam computed tomography (CBCT) are affected by general bone mineral density (BMD) in postmenopausal women, and to evaluate whether CBCT can be used for predicting the risk of osteoporosis. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 26, 2021 Category: ENT & OMF Authors: Slaidina Anda, Nikitina Evija, Abeltins Andris, Soboleva Una, Lejnieks Aivars Tags: Original Article Source Type: research

Ill-defined extensive radiolucent lesion of the left posterior mandible
A 60-year-old female was referred by an outside oral and maxillofacial surgeon for evaluation of a left posterior mandibular “lesion”. The patient estimated she first experienced pain associated with the left mandibular posterior teeth approximately six months prior to presentation. She also experienced progressive difficulty with mastication on the left side. She was seen by her general dentist and was referred to an oral surgeon for extraction of the left mandibular posterior teeth due to periodontally compromised dentition. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 26, 2021 Category: ENT & OMF Authors: Kyle Stiefel, Pooja Gangwani, Darren Cox, Antonia Kolokythas Source Type: research

Efficacy of diffusion-weighted magnetic resonance imaging in the diagnosis of osteomyelitis of the mandible
This retrospective cohort study aimed to determine the diagnostic utility of apparent diffusion coefficient (ADC) values in the quantitative evaluation of mandibular osteomyelitis. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 20, 2021 Category: ENT & OMF Authors: Hirotaka Muraoka, Naohisa Hirahara, Kotaro Ito, Shunya Okada, Takumi Kondo, Takashi Kaneda Source Type: research

An association of the MCP-1 and CCR2 gene polymorphisms with Oral Lichen Planus
The purpose of this study was to investigate the frequency of MCP-1 CCR2 gene polymorphisms in Turkish oral lichen planus (OLP) patients. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 20, 2021 Category: ENT & OMF Authors: Ozgur Ozturk, Bedia Cakmakoglu, Gizem Nur Ozturk, Meral Unur Source Type: research

Unicystic ameloblastoma with stromal giant cells: A case series of a rare entity
We report two new cases with histological features compatible with unicystic ameloblastoma with stromal giant cells. CD68 immunohistochemical staining of the giant cells supported a histiocytic origin. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 20, 2021 Category: ENT & OMF Authors: Liam Robinson, Felipe Paiva Fonseca, J úlio César Tanos Lacerda, Wilie F.P. van Heerden Source Type: research

Awareness of the risk of radiation-related caries in Head and neck cancer patients: A survey of physicians, dentists, and patients
Radiation-related caries (RRC) is one of the most aggressive complications of radiotherapy (RT) in head and neck cancer (HNC) survivors. Lack of RRC awareness may contribute to the occurrence of this oral cavity complication. RRC may be considered a “forgotten oral complication” by HNC patients, oncologists, and dentists. The present study aimed to assess the level of awareness of RRC among physicians, dentists, and patients. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 20, 2021 Category: ENT & OMF Authors: Beatriz Nascimento Figueiredo Lebre Martins, Nat ália Rangel Palmier, Ana Carolina Prado Ribeiro, Mario Fernando de Goes, Marcio Ajudarte Lopes, Thais Bianca Brandão, Cesar Rivera, César Augusto Migliorati, Joel B. Epstein, Alan Roger Santos-Silva Source Type: research

Thyroid Carcinoma Discovered Incidentally During Surgical Resection of Head and Neck Squamous Cell Carcinoma: A Case Series
The occurrence of two synchronous primary cancers of different origin in the head and neck region is rare. The incidence of thyroid carcinoma found during surgical resection of primary oral squamous cell carcinoma (SCCa) is about 0.3-1.9% of patients. Because of the rarity of cases, there is no consensus on management. To clarify significance and management of such lesions, we report 13 cases in which incidental thyroid carcinoma was discovered during surgical resection for primary oral SCCa. A total of 1295 cases of head and neck SCCa from a four-year period were reviewed, of which we found 13 cases of concurrent thyroid ...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 20, 2021 Category: ENT & OMF Authors: Xinyuan Ning, Jaimie Hittman, Joshua Lubek, Rana Malek Source Type: research

The efficacy of diffusion-weighted magnetic resonance imaging in the diagnosis of osteomyelitis of the mandible
This retrospective cohort study aimed to determine the diagnostic utility of apparent diffusion coefficient (ADC) values in the quantitative evaluation of mandibular osteomyelitis. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 20, 2021 Category: ENT & OMF Authors: Hirotaka Muraoka, Naohisa Hirahara, Kotaro Ito, Shunya Okada, Takumi Kondo, Takashi Kaneda Tags: Original Article Source Type: research

Clinical significance of miR-142-3p in oral lichen planus and its regulatory role in keratinocyte proliferation
This study aimed to investigate the role and underlying mechanism of miR-142-3p in OLP. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 20, 2021 Category: ENT & OMF Authors: Zhichao Meng, Jian Wang, Mingyan Hu, Leilei Li, Kuimei Wang Tags: Original Article Source Type: research

Association of high cardiovascular risk and diabetes with calcified carotid artery atheromas depicted on panoramic radiographs
To evaluate whether estimates of risk of future cardiovascular events and death and established or unknown diabetes are significantly associated with calcified carotid artery atheromas (CCAAs) on panoramic radiographs (PRs). The main focus was on men and women without previous myocardial infarction (MI). (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 18, 2021 Category: ENT & OMF Authors: Nils Gustafsson, Jan Ahlqvist, Anna Norhammar, Ulf N äslund, Lars Rydén, Per Wester, Eva Levring Jäghagen Tags: Original Article Source Type: research

Clear cell odontogenic carcinoma: report of 3 new cases and summary of 124 reported cases
Clear cell odontogenic carcinoma (CCOC) is a rare and hard-to-diagnose tumor first described by Hansen et al. in 1985. CCOC is associated with aggressive clinical behavior, metastasis, low survival rate, and difficulty in diagnosis. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: A Abdolrahmani, N Kardooni Source Type: research

Relationship between oral melanotic hyperpigmentation and serum inflammatory cytokines in hiv seropositive patients —a case control study
Oral melanotic hyperpigmentation in patients with HIV (HIV-OMH) has been attributed to the use of antifungal agents or antiretroviral drugs; alternatively, HIV-induced cytokine dysregulation causing activation of melanogenesis pathway has been well documented. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: EO Abe, AO Adisa, BF Adeyemi, FJ Owotade Source Type: research

Evaluation of cancer stem cell marker, bmi-1 expression in oral submucous fibrosis with and without malignant transformation
Epithelial-mesenchymal transition plays a crucial role in the pathogenesis of oral submucous fibrosis (OSF) as well as in progression of carcinogenesis while inducing stem-like properties in epithelial cells. Hence, it is important to discover possibilities of using stem cell markers to predict malignant transformation (MT) in OSF. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: WAMUL Abeyasinghe, PB Tennakoon, PR Jayasooriya Source Type: research

Salivary gland lesions with oncocytic change: a 20-year retrospective evaluation
Oncocytic change, a manifestation of abundant mitochondria within a cell, often occurs in salivary gland lesions. This phenomenon is thought to represent an adaptive or metaplastic change associated with increasing age or exposure to agents that induce senescence. A 20-year retrospective study was carried out on salivary gland lesions diagnosed at University College London Hospitals with a view to evaluating the incidence and prevalence of oncocytic change. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: OK Adegun, R Agrawal, A Jay Source Type: research

Diverse histomorphology of osteosarcoma; illustration of twelve cases
Head and neck osteosarcomas are rare and comprise less than 1% of tumors of the head and neck. Their management is relegated to specialist head and neck centers, which means that only a small team of head and neck pathologists analyzes the resected tumors. Their rarity and the need to identify malignant osteoid in biopsies makes their diagnosis challenging. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: A Jay, N Kalavrezos, D Sinha, OK Adegun, R Agrawal Source Type: research

Chlamydia trachomatis expresses phylogenetically homologous proteins to human papilloma virus type 16: inferences for oral and oropharyngeal squamous cell carcinoma
Oral and oropharyngeal squamous cell carcinoma have been linked to infection by human papilloma virus (HPV) types 16 and 18. They produce proteins E6 and E7 that interfere with p53 and pRb1 proteins and hence support oncogenesis. HPV infection is typically via oro-genital contact and other organisms cohabiting the genitalia may have had sufficient time for a genetic exchange with HPV oncoproteins and hence develop oncogenic potential also within the oral cavity. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: GO Oboli, EO Abe, AO Adisa Source Type: research

Oral verrucous lesions —a diagnostic dilemma: a 10-year institutional experience and literature review
Oral verrucous-papillary lesions (including proliferative verrucous leukoplakia) with malignant/frankly malignant potential are assigned diverse terminology resulting from lack of standard clinical and histologic diagnostic criteria, with implications for management. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: R Agrawal, A Jay, O Adegun Source Type: research

Plastination, the ideal method to preserve surgical specimens in oral pathology
Plastination is a procedure created in 1977 by anatomist Gunther von Hagens at the University of Heidelberg in Germany and it aims to preserve biological tissue specimens. This technique is based on the substitution of body fluids (water, lipids) by polymers that allow indefinite material preservation, without damaging its structure and rendering easy manipulation for further study. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: B Aldape, L Di éguez, IE Candanosa Source Type: research

Two peas in a pod: an incidental finding of sclerosing polycystic adenosis within a pleomorphic adenoma
A 55-year-old male patient was urgently referred to the local ear, nose, and throat surgery department with a 1-cm left parotid lump. Initial core biopsy was suggestive of a pleomorphic adenoma with some atypical features. The patient underwent a left parotidectomy. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: S AlGhamdi, A Alfurhud, SA Khurram, AA Omari Source Type: research

A rare case of cheilitis glandularis affecting the upper lip: case report and literature review
Cheilitis glandularis (CG) is an uncommon inflammatory disease that affects minor salivary glands, predominantly reported of the lower lips. Cheilitis glandularis has clinical and pathologic features similar to that of stomatitis glandularis (SG). The authors differentiated the 2 because the affected sites in SG are not limited to the lower lip. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: AS Ali, Z Khan, M Pemberton Source Type: research

Perineural invasion in oral squamous cell carcinoma: incidence, clinical impact and molecular insight
Perineural invasion (PNI) has been associated with poor prognosis in oral squamous cell carcinoma (OSCC). Nerve growth factor (NGF) and its receptor tyrosine kinase A (TrkA) may play a role in PNI in OSCC. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: H Alkhadar, M Macluskey, S White, I Ellis Source Type: research

Gold nanoparticles reflectance discriminate benign from malignant salivary gland neoplasms
Nanoparticle-based contrast agents have been used as an imaging tool for selectively detecting cancerous processes. Epidermal growth factor receptor (EGFR) has been found to be dysregulated in malignant salivary gland tumors (MSGTs) and can serve as an ideal target for nanoparticle-based contrast agents using gold nanoparticles (GNPs) bio-conjugated to anti-EGFR monoclonal antibodies. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: S Sudri, I Allon, I Abu El-Naaj, D Fixler, A Hirshberg Source Type: research

Novel advances in staging and grading of early oral tongue cancer: a multicenter study
Recent research has proposed modifications for the TNM staging and the World Health Organization (WHO) histopathologic grading system of oral cancer. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: A Almangush, RD Coletta, AA M äkitie, T Salo, I Leivo Source Type: research

Novel neuropilin 2-targeting biologic for the treatment of oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) is the sixth most common cancer and a leading cause of cancer mortality in some countries. Recently, our laboratory identified the neuropilin-2 (NRP2) transmembrane glycoprotein as a novel target in OSCC and its associated vasculature in patient biopsies and mouse carcinogenesis models. NRP2 is a co-receptor for the angiogenic factor vascular endothelial growth factor (VEGF)-A with VEGFR2 and the lymphangiogenic factors VEGF-C/D with VEGFR3 and is abundantly expressed in growing endothelium. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: AM Almazyad, Y Gao, S Shahrabi-Farahani, A Gartung, L Sui, R Das, DE Costea, RS Watnick, D Panigrahy, RM Adam, DR Bielenberg Source Type: research