MAML2-Rearrranged Sclerosing Mucoepidermoid Carcinoma of Submandibular Gland: An Incidental Finding in a Patient with History of Recurrent Sialadenitis and Sj ögren's syndrome

We present a new case of sclerosing mucoepidermoid carcinoma (SMEC) with MAML2 rearrangements. A 49-year-old woman with Sj ögren's syndrome experienced recurrent submandibular sialadenitis and sialolithiasis, leading to the removal of her right gland. Postoperative imaging revealed a calcified mass in her left gland which was subsequently resected. The pathological examination revealed a well-defined tumor with extensi ve fibrous stroma, predominantly epidermoid cells, and occasional mucinous components.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research