Association of DOK3 and infiltrated tumor-associated macrophages with risk for the prognosis of Porphyromonas gingivalis-infected oral cancer: a 12-year data analysis of 200 patients from a tertiary teaching hospital, Urumqi, China
While there is an understanding of the association between the expression of Porphyromonas gingivalis (P. gingivalis) and prognosis of oral squamous cell carcinoma (OSCC), significance specially to address the re... (Source: BMC Cancer)
Source: BMC Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Chenxi Li, Muqiu Li, Wei Wei, Zhengye Wang, Jingwen Yu and Zhongcheng Gong Tags: Research Source Type: research

E-cigarettes in Nigeria: A scoping review of evidence
CONCLUSION: There is an urgent need for more scientific investigations on the sociodemographic, economic, health, and regulatory landscape of e-cigarettes in Nigeria, as robust empirical evidence is needed for the effective planning, implementation, and evaluation of evidence-based policies and interventions on e-cigarettes control and regulation in Nigeria.PMID:38660005 | PMC:PMC11040567 | DOI:10.1002/hsr2.2074 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Oluwatobi E Adegbile Oluwatomilayo D Adeniji Jimoh Amzat Kehinde K Kanmodi Source Type: research

The efficiency and safety of low-dose apatinib combined with oral vinorelbine in pretreated HER2-negative metastatic breast cancer
CONCLUSION: Low-dose apatinib combined with oral vinorelbine demonstrates potential efficacy and well tolerated for pretreated HER2-negative mBC.PMID:38659376 | DOI:10.1002/cam4.7181 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Jia-Yi Huang Xue-Lian Chen Xiao-Feng Xie Lin Song Li-Ping Chen Xiao-Feng Lan Xue Bai Xiao Chen Cai-Wen Du Source Type: research

Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research

Implications of innate lymphoid cells in oral diseases
Int Immunopharmacol. 2024 Apr 24;133:112122. doi: 10.1016/j.intimp.2024.112122. Online ahead of print.ABSTRACTInnate lymphoid cells (ILCs), as newly discovered antigen-independent innate immune cells, respond promptly to stimuli by secreting effector cytokines to exert effector functions similar to those of T cells. ILCs predominantly reside at mucosal sites and play critical roles in defending against infections, maintaining mucosal homeostasis, regulating inflammatory and immune responses, and participating in tumorigenesis. Recently, there has been a growing interest in the role of ILCs in oral diseases. This review out...
Source: International Immunopharmacology - April 25, 2024 Category: Allergy & Immunology Authors: Si-Ting Hu Gang Zhou Jing Zhang Source Type: research

Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research

Direct oral anticoagulant-associated bleeding complications in patients with gastrointestinal cancer and venous thromboembolism
CONCLUSIONS: Upper GI cancer, but not lower GI cancer, as compared to non-GI cancer was associated with a higher risk for major bleeding during anticoagulation therapy with DOACs.CLINICAL TRIAL REGISTRATION: URL: http://www.umin.ac.jp/ctr/index.htm Unique identifier: UMIN000044816.PMID:38664165 | DOI:10.1016/j.ejim.2024.04.012 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - April 25, 2024 Category: Internal Medicine Authors: Yuji Nishimoto Yugo Yamashita Takeshi Morimoto Ryuki Chatani Kazuhisa Kaneda Nobutaka Ikeda Yohei Kobayashi Satoshi Ikeda Kitae Kim Moriaki Inoko Toru Takase Yukihito Sato Tetsuya Watanabe Takahisa Yamada Masatake Fukunami Takeshi Kimura COMMAND VTE Regis Source Type: research

Implications of innate lymphoid cells in oral diseases
Int Immunopharmacol. 2024 Apr 24;133:112122. doi: 10.1016/j.intimp.2024.112122. Online ahead of print.ABSTRACTInnate lymphoid cells (ILCs), as newly discovered antigen-independent innate immune cells, respond promptly to stimuli by secreting effector cytokines to exert effector functions similar to those of T cells. ILCs predominantly reside at mucosal sites and play critical roles in defending against infections, maintaining mucosal homeostasis, regulating inflammatory and immune responses, and participating in tumorigenesis. Recently, there has been a growing interest in the role of ILCs in oral diseases. This review out...
Source: International Immunopharmacology - April 25, 2024 Category: Allergy & Immunology Authors: Si-Ting Hu Gang Zhou Jing Zhang Source Type: research

Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research

Direct oral anticoagulant-associated bleeding complications in patients with gastrointestinal cancer and venous thromboembolism
CONCLUSIONS: Upper GI cancer, but not lower GI cancer, as compared to non-GI cancer was associated with a higher risk for major bleeding during anticoagulation therapy with DOACs.CLINICAL TRIAL REGISTRATION: URL: http://www.umin.ac.jp/ctr/index.htm Unique identifier: UMIN000044816.PMID:38664165 | DOI:10.1016/j.ejim.2024.04.012 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - April 25, 2024 Category: Internal Medicine Authors: Yuji Nishimoto Yugo Yamashita Takeshi Morimoto Ryuki Chatani Kazuhisa Kaneda Nobutaka Ikeda Yohei Kobayashi Satoshi Ikeda Kitae Kim Moriaki Inoko Toru Takase Yukihito Sato Tetsuya Watanabe Takahisa Yamada Masatake Fukunami Takeshi Kimura COMMAND VTE Regis Source Type: research

Transdermal Opioids and the Quality of Life of the Cancer Patient: A Systematic Literature Review
CONCLUSIONS: Transdermal therapy was suggested to have several advantages over oral opioid therapy in enhancing cancer patients' QoL. These benefits span various dimensions, including pain management, physical functioning, mental health, vitality, overall patient improvement, anger/aversion, strength/activity, general QoL, cognitive and emotional functions, fatigue, and insomnia.PMID:38659244 | DOI:10.1177/10600280241247363 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Patricia Santos Reis Durval Campos Kraychete Emilie de Magalh ães Pedreira Eduardo Silva Reis Barreto C ésar Romero Antunes Júnior Vinicius Borges Alencar Anna Karla do Nascimento Souza Liliane Elze Falc ão Lins-Kusterer Liana Maria Torres de Araujo A Source Type: research

Direct oral anticoagulant-associated bleeding complications in patients with gastrointestinal cancer and venous thromboembolism
CONCLUSIONS: Upper GI cancer, but not lower GI cancer, as compared to non-GI cancer was associated with a higher risk for major bleeding during anticoagulation therapy with DOACs.CLINICAL TRIAL REGISTRATION: URL: http://www.umin.ac.jp/ctr/index.htm Unique identifier: UMIN000044816.PMID:38664165 | DOI:10.1016/j.ejim.2024.04.012 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - April 25, 2024 Category: Internal Medicine Authors: Yuji Nishimoto Yugo Yamashita Takeshi Morimoto Ryuki Chatani Kazuhisa Kaneda Nobutaka Ikeda Yohei Kobayashi Satoshi Ikeda Kitae Kim Moriaki Inoko Toru Takase Yukihito Sato Tetsuya Watanabe Takahisa Yamada Masatake Fukunami Takeshi Kimura COMMAND VTE Regis Source Type: research

The efficiency and safety of low ‐dose apatinib combined with oral vinorelbine in pretreated HER2‐negative metastatic breast cancer
ConclusionLow-dose apatinib combined with oral vinorelbine demonstrates potential efficacy and well tolerated for pretreated HER2-negative mBC. (Source: Cancer Medicine)
Source: Cancer Medicine - April 25, 2024 Category: Cancer & Oncology Authors: Jia ‐Yi Huang, Xue‐Lian Chen, Xiao‐Feng Xie, Lin Song, Li‐Ping Chen, Xiao‐Feng Lan, Xue Bai, Xiao Chen, Cai‐Wen Du Tags: RESEARCH ARTICLE Source Type: research

HPV infection and its correlation with p53 and Bcl-2 among pregnant mothers and their infants
AbstractThe investigation of perinatal transmission of HPV is vital for early screening of cervical/oral cancers. Here, transmission of HPV from the pregnant women to their infants was studied. p53 and Bcl-2 expressions and their correlations with HPV infection were examined. HPV infection was detected in the cervical and oral swabs of 135 mother-baby pairs employing both PCR and HC-II methods. 1  year follow-up with an interim visit at 3 months for mothers and 6 months for babies was performed. Immunocytochemistry of p53 and Bcl-2 using the streptavidin–biotin peroxidase method was performed. Prevalence of HPV infect...
Source: Virus Genes - April 25, 2024 Category: Genetics & Stem Cells Source Type: research

Comparative study of conventional exfoliative cytology and centrifuged liquid ‑based cytology in oral leukoplakia and oral squamous cell carcinoma patients
Conclusion: CLBC is better and give clearer vision as compared to conventional cytology and can be used in the early diagnosis.Key Words: Cytology, early diagnosis, leukoplakia, oral cancer  HighlightR. Jayabalan:  Pubmed,Google Scholar (Source: Dental Research Journal)
Source: Dental Research Journal - April 24, 2024 Category: Dentistry Source Type: research