Tocilizumab in severe COVID-19: A promise fulfilled
Eur J Intern Med. 2021 Nov 22:S0953-6205(21)00390-3. doi: 10.1016/j.ejim.2021.11.015. Online ahead of print.NO ABSTRACTPMID:34836747 | PMC:PMC8606258 | DOI:10.1016/j.ejim.2021.11.015 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 27, 2021 Category: Internal Medicine Authors: Marcel Levi Source Type: research

The 2021 ESC guidelines on cardiovascular prevention: Whether the ends justify the means
Eur J Intern Med. 2021 Nov 22:S0953-6205(21)00386-1. doi: 10.1016/j.ejim.2021.11.012. Online ahead of print.NO ABSTRACTPMID:34823967 | DOI:10.1016/j.ejim.2021.11.012 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 26, 2021 Category: Internal Medicine Authors: Claudio Cimminiello Charalambos Vlachopulos Marco De Carlo Source Type: research

The 2021 ESC guidelines on cardiovascular prevention: Whether the ends justify the means
Eur J Intern Med. 2021 Nov 22:S0953-6205(21)00386-1. doi: 10.1016/j.ejim.2021.11.012. Online ahead of print.NO ABSTRACTPMID:34823967 | DOI:10.1016/j.ejim.2021.11.012 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 26, 2021 Category: Internal Medicine Authors: Claudio Cimminiello Charalambos Vlachopulos Marco De Carlo Source Type: research

Colchicine for COVID-19: Hype or hope?
Eur J Intern Med. 2021 Nov 13:S0953-6205(21)00387-3. doi: 10.1016/j.ejim.2021.11.011. Online ahead of print.NO ABSTRACTPMID:34810043 | PMC:PMC8590489 | DOI:10.1016/j.ejim.2021.11.011 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 23, 2021 Category: Internal Medicine Authors: Chia Siang Kow Dinesh Sangarran Ramachandram Syed Shahzad Hasan Source Type: research

Colchicine for COVID-19: Hype or hope?
Eur J Intern Med. 2021 Nov 13:S0953-6205(21)00387-3. doi: 10.1016/j.ejim.2021.11.011. Online ahead of print.NO ABSTRACTPMID:34810043 | PMC:PMC8590489 | DOI:10.1016/j.ejim.2021.11.011 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 23, 2021 Category: Internal Medicine Authors: Chia Siang Kow Dinesh Sangarran Ramachandram Syed Shahzad Hasan Source Type: research

Colchicine for COVID-19: Hype or hope?
Eur J Intern Med. 2021 Nov 13:S0953-6205(21)00387-3. doi: 10.1016/j.ejim.2021.11.011. Online ahead of print.NO ABSTRACTPMID:34810043 | DOI:10.1016/j.ejim.2021.11.011 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 23, 2021 Category: Internal Medicine Authors: Chia Siang Kow Dinesh Sangarran Ramachandram Syed Shahzad Hasan Source Type: research

Procedural myocardial infarction and major myocardial injury after percutaneous coronary interventions in chronic coronary syndrome: Is the fog really waning?
Eur J Intern Med. 2021 Nov 18:S0953-6205(21)00382-4. doi: 10.1016/j.ejim.2021.11.007. Online ahead of print.ABSTRACTThe prognostic role of procedural myocardial infarction (MI) is still controversial and matter of ongoing debate in the scientific community. A recent ESC Consensus Document confirmed the prognostic importance of type 4a MI and defined equally clinically relevant the major peri‑procedural myocardial injury, defined as the same cardiac Troponin cut-off threshold of type 4a MI without peri‑procedural angiographic complications, electrocardiographic or imaging evidence of new myocardial ischaemia. In the pre...
Source: European Journal of Internal Medicine - November 22, 2021 Category: Internal Medicine Authors: Stefano De Servi Antonio Landi Source Type: research

Procedural myocardial infarction and major myocardial injury after percutaneous coronary interventions in chronic coronary syndrome: Is the fog really waning?
Eur J Intern Med. 2021 Nov 18:S0953-6205(21)00382-4. doi: 10.1016/j.ejim.2021.11.007. Online ahead of print.ABSTRACTThe prognostic role of procedural myocardial infarction (MI) is still controversial and matter of ongoing debate in the scientific community. A recent ESC Consensus Document confirmed the prognostic importance of type 4a MI and defined equally clinically relevant the major peri‑procedural myocardial injury, defined as the same cardiac Troponin cut-off threshold of type 4a MI without peri‑procedural angiographic complications, electrocardiographic or imaging evidence of new myocardial ischaemia. In the pre...
Source: European Journal of Internal Medicine - November 22, 2021 Category: Internal Medicine Authors: Stefano De Servi Antonio Landi Source Type: research

Learning in times of stress: Lessons from COVID-19 that will last throughout this century
Eur J Intern Med. 2021 Nov 12:S0953-6205(21)00377-0. doi: 10.1016/j.ejim.2021.11.002. Online ahead of print.ABSTRACTSystems tend toward inertia until an external pressure pushes them toward change; thus, a situation of crisis such as the COVID-19 pandemic represents an opportunity for technological innovation. The prevailing need for treatments and vaccines has impelled innovation in the world of randomized clinical trials (RCT), resorting to ideas that had been floating around for a while. Is this merely a circumstantial phenomenon or are new methods here to stay?PMID:34801401 | DOI:10.1016/j.ejim.2021.11.002 (Source: Eur...
Source: European Journal of Internal Medicine - November 21, 2021 Category: Internal Medicine Authors: Paula Jim énez-Fonseca Ram ón Salazar Vicent Valent í Alberto Carmona-Bayonas Giancarlo Agnelli Source Type: research

Trends and outcomes of opioid-related cardiac arrest in a contemporary US population
Eur J Intern Med. 2021 Nov 16:S0953-6205(21)00380-0. doi: 10.1016/j.ejim.2021.11.004. Online ahead of print.ABSTRACTBACKGROUND: Opioid abuse is a worldwide public health issue, and deaths related to opioid abuse are increasing. We aimed to investigate trends, predictors, and outcomes of cardiac arrest in patients with opioid abuse.METHODS: All hospitalizations for primary diagnosis of cardiac arrest between 2012 and 2018 identified in the Nationwide Inpatient Sample were categorized into those with or without a secondary diagnosis of opioid overdose. Multivariable logistic regression was used to analyze in-hospital outcome...
Source: European Journal of Internal Medicine - November 20, 2021 Category: Internal Medicine Authors: Senada S Malik Wilbert S Aronow Alexandros Briasoulis Source Type: research

Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors for cardiovascular and renal protection: A treatment approach far beyond their glucose-lowering effect
Eur J Intern Med. 2021 Nov 16:S0953-6205(21)00383-6. doi: 10.1016/j.ejim.2021.11.008. Online ahead of print.ABSTRACTFindings from cardiovascular outcome trials on certain newer glucose-lowering drugs have shown clear cardiovascular and renal benefits. In this review, we provide an updated overview of glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter 2 (SGLT-2) inhibitors in terms of cardiovascular and renal protection. Both drugs have been described as diabetes/disease-modifying drugs. There is robust evidence on the benefits of GLP-1 receptor agonists in renal disease and atherosclerotic c...
Source: European Journal of Internal Medicine - November 20, 2021 Category: Internal Medicine Authors: Ricardo G ómez-Huelgas Jaime Sanz-C ánovas Lidia Cobos-Palacios Almudena L ópez-Sampalo Luis M P érez-Belmonte Source Type: research

Anticoagulant therapy for COVID-19: What we have learned and what are the unanswered questions?
Eur J Intern Med. 2021 Nov 11:S0953-6205(21)00378-2. doi: 10.1016/j.ejim.2021.11.003. Online ahead of print.NO ABSTRACTPMID:34799234 | PMC:PMC8580837 | DOI:10.1016/j.ejim.2021.11.003 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 20, 2021 Category: Internal Medicine Authors: Dimitrios Giannis James D Douketis Alex C Spyropoulos Source Type: research

Trends and outcomes of opioid-related cardiac arrest in a contemporary US population
Eur J Intern Med. 2021 Nov 16:S0953-6205(21)00380-0. doi: 10.1016/j.ejim.2021.11.004. Online ahead of print.ABSTRACTBACKGROUND: Opioid abuse is a worldwide public health issue, and deaths related to opioid abuse are increasing. We aimed to investigate trends, predictors, and outcomes of cardiac arrest in patients with opioid abuse.METHODS: All hospitalizations for primary diagnosis of cardiac arrest between 2012 and 2018 identified in the Nationwide Inpatient Sample were categorized into those with or without a secondary diagnosis of opioid overdose. Multivariable logistic regression was used to analyze in-hospital outcome...
Source: European Journal of Internal Medicine - November 20, 2021 Category: Internal Medicine Authors: Senada S Malik Wilbert S Aronow Alexandros Briasoulis Source Type: research

Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors for cardiovascular and renal protection: A treatment approach far beyond their glucose-lowering effect
Eur J Intern Med. 2021 Nov 16:S0953-6205(21)00383-6. doi: 10.1016/j.ejim.2021.11.008. Online ahead of print.ABSTRACTFindings from cardiovascular outcome trials on certain newer glucose-lowering drugs have shown clear cardiovascular and renal benefits. In this review, we provide an updated overview of glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter 2 (SGLT-2) inhibitors in terms of cardiovascular and renal protection. Both drugs have been described as diabetes/disease-modifying drugs. There is robust evidence on the benefits of GLP-1 receptor agonists in renal disease and atherosclerotic c...
Source: European Journal of Internal Medicine - November 20, 2021 Category: Internal Medicine Authors: Ricardo G ómez-Huelgas Jaime Sanz-C ánovas Lidia Cobos-Palacios Almudena L ópez-Sampalo Luis M P érez-Belmonte Source Type: research

Anticoagulant therapy for COVID-19: What we have learned and what are the unanswered questions?
Eur J Intern Med. 2021 Nov 11:S0953-6205(21)00378-2. doi: 10.1016/j.ejim.2021.11.003. Online ahead of print.NO ABSTRACTPMID:34799234 | DOI:10.1016/j.ejim.2021.11.003 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 20, 2021 Category: Internal Medicine Authors: Dimitrios Giannis James D Douketis Alex C Spyropoulos Source Type: research

Anakinra in COVID-19: A step closer to the cure
Eur J Intern Med. 2021 Nov 11:S0953-6205(21)00379-4. doi: 10.1016/j.ejim.2021.11.005. Online ahead of print.NO ABSTRACTPMID:34794858 | PMC:PMC8580858 | DOI:10.1016/j.ejim.2021.11.005 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 19, 2021 Category: Internal Medicine Authors: Fotios Barkas Eirini Christaki Evangelos Liberopoulos Maria Kosmidou Haralampos Milionis Source Type: research

Anakinra in COVID-19: A step closer to the cure
Eur J Intern Med. 2021 Nov 11:S0953-6205(21)00379-4. doi: 10.1016/j.ejim.2021.11.005. Online ahead of print.NO ABSTRACTPMID:34794858 | DOI:10.1016/j.ejim.2021.11.005 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 19, 2021 Category: Internal Medicine Authors: Fotios Barkas Eirini Christaki Evangelos Liberopoulos Maria Kosmidou Haralampos Milionis Source Type: research

Neutrophil count, lymphocyte count and neutrophil-to-lymphocyte ratio in relation to response to adjunctive dexamethasone treatment in community-acquired pneumonia
Eur J Intern Med. 2021 Nov 12:S0953-6205(21)00371-X. doi: 10.1016/j.ejim.2021.10.030. Online ahead of print.ABSTRACTBACKGROUND: It is hypothesised that community-acquired pneumonia (CAP) patients with more severe disease or inflammation might benefit more from adjunctive corticosteroid treatment. Neutrophil count, lymphocyte count and neutrophil-lymphocyte ratio (NLR) have been associated with inflammation and disease severity in CAP. We investigated the interaction between these parameters and adjunctive dexamethasone effects on clinical outcomes in CAP.METHODS: We conducted a post hoc analysis of the randomised placebo-c...
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Esther Wittermans Ewoudt Mw van de Garde G Paul Voorn Arnoud F Aldenkamp Rob Janssen Jan C Grutters Willem Jan W Bos Santeon-CAP study group Source Type: research

Infective endocarditis, is there a goal beyond antibiotics and surgery?
Eur J Intern Med. 2021 Nov 12:S0953-6205(21)00373-3. doi: 10.1016/j.ejim.2021.10.033. Online ahead of print.NO ABSTRACTPMID:34782192 | DOI:10.1016/j.ejim.2021.10.033 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Benoit Guery Matthaios Papadimitriou-Olivgeris Source Type: research

Representativity of women and racial/ethnic minorities in randomized clinical trials on bempedoic acid: Positive efforts and lacking data
Eur J Intern Med. 2021 Nov 13:S0953-6205(21)00381-2. doi: 10.1016/j.ejim.2021.11.006. Online ahead of print.NO ABSTRACTPMID:34782193 | DOI:10.1016/j.ejim.2021.11.006 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Federica Fogacci Davide Gori Arrigo F G Cicero Source Type: research

Neutrophil count, lymphocyte count and neutrophil-to-lymphocyte ratio in relation to response to adjunctive dexamethasone treatment in community-acquired pneumonia
Eur J Intern Med. 2021 Nov 12:S0953-6205(21)00371-X. doi: 10.1016/j.ejim.2021.10.030. Online ahead of print.ABSTRACTBACKGROUND: It is hypothesised that community-acquired pneumonia (CAP) patients with more severe disease or inflammation might benefit more from adjunctive corticosteroid treatment. Neutrophil count, lymphocyte count and neutrophil-lymphocyte ratio (NLR) have been associated with inflammation and disease severity in CAP. We investigated the interaction between these parameters and adjunctive dexamethasone effects on clinical outcomes in CAP.METHODS: We conducted a post hoc analysis of the randomised placebo-c...
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Esther Wittermans Ewoudt Mw van de Garde G Paul Voorn Arnoud F Aldenkamp Rob Janssen Jan C Grutters Willem Jan W Bos Santeon-CAP study group Source Type: research

Infective endocarditis, is there a goal beyond antibiotics and surgery?
Eur J Intern Med. 2021 Nov 12:S0953-6205(21)00373-3. doi: 10.1016/j.ejim.2021.10.033. Online ahead of print.NO ABSTRACTPMID:34782192 | DOI:10.1016/j.ejim.2021.10.033 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Benoit Guery Matthaios Papadimitriou-Olivgeris Source Type: research

Representativity of women and racial/ethnic minorities in randomized clinical trials on bempedoic acid: Positive efforts and lacking data
Eur J Intern Med. 2021 Nov 13:S0953-6205(21)00381-2. doi: 10.1016/j.ejim.2021.11.006. Online ahead of print.NO ABSTRACTPMID:34782193 | DOI:10.1016/j.ejim.2021.11.006 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Federica Fogacci Davide Gori Arrigo F G Cicero Source Type: research

Neutrophil count, lymphocyte count and neutrophil-to-lymphocyte ratio in relation to response to adjunctive dexamethasone treatment in community-acquired pneumonia
Eur J Intern Med. 2021 Nov 12:S0953-6205(21)00371-X. doi: 10.1016/j.ejim.2021.10.030. Online ahead of print.ABSTRACTBACKGROUND: It is hypothesised that community-acquired pneumonia (CAP) patients with more severe disease or inflammation might benefit more from adjunctive corticosteroid treatment. Neutrophil count, lymphocyte count and neutrophil-lymphocyte ratio (NLR) have been associated with inflammation and disease severity in CAP. We investigated the interaction between these parameters and adjunctive dexamethasone effects on clinical outcomes in CAP.METHODS: We conducted a post hoc analysis of the randomised placebo-c...
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Esther Wittermans Ewoudt Mw van de Garde G Paul Voorn Arnoud F Aldenkamp Rob Janssen Jan C Grutters Willem Jan W Bos Santeon-CAP study group Source Type: research

Infective endocarditis, is there a goal beyond antibiotics and surgery?
Eur J Intern Med. 2021 Nov 12:S0953-6205(21)00373-3. doi: 10.1016/j.ejim.2021.10.033. Online ahead of print.NO ABSTRACTPMID:34782192 | DOI:10.1016/j.ejim.2021.10.033 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Benoit Guery Matthaios Papadimitriou-Olivgeris Source Type: research

Representativity of women and racial/ethnic minorities in randomized clinical trials on bempedoic acid: Positive efforts and lacking data
Eur J Intern Med. 2021 Nov 13:S0953-6205(21)00381-2. doi: 10.1016/j.ejim.2021.11.006. Online ahead of print.NO ABSTRACTPMID:34782193 | DOI:10.1016/j.ejim.2021.11.006 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 16, 2021 Category: Internal Medicine Authors: Federica Fogacci Davide Gori Arrigo F G Cicero Source Type: research

Hematuria and subsequent long-term risk of end-stage kidney disease: A Danish population-based cohort study
CONCLUSION: A hospital-based hematuria diagnosis in patients with no apparent underlying cause of hematuria is a marker of an increased risk of future ESKD.PMID:34776328 | DOI:10.1016/j.ejim.2021.10.021 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 15, 2021 Category: Internal Medicine Authors: Kristine Fogh S øren Viborg Vestergaard Christian Fynbo Christiansen Lars Pedersen Dorothea Nitsch Mette N ørgaard Source Type: research

Mobile stroke unit is not a stroke unit
Eur J Intern Med. 2021 Nov 11:S0953-6205(21)00372-1. doi: 10.1016/j.ejim.2021.10.032. Online ahead of print.NO ABSTRACTPMID:34776329 | DOI:10.1016/j.ejim.2021.10.032 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 15, 2021 Category: Internal Medicine Authors: Stefano Ricci Danilo Toni Mauro Silvestrini Source Type: research

Hematuria and subsequent long-term risk of end-stage kidney disease: A Danish population-based cohort study
CONCLUSION: A hospital-based hematuria diagnosis in patients with no apparent underlying cause of hematuria is a marker of an increased risk of future ESKD.PMID:34776328 | DOI:10.1016/j.ejim.2021.10.021 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 15, 2021 Category: Internal Medicine Authors: Kristine Fogh S øren Viborg Vestergaard Christian Fynbo Christiansen Lars Pedersen Dorothea Nitsch Mette N ørgaard Source Type: research

Mobile stroke unit is not a stroke unit
Eur J Intern Med. 2021 Nov 11:S0953-6205(21)00372-1. doi: 10.1016/j.ejim.2021.10.032. Online ahead of print.NO ABSTRACTPMID:34776329 | DOI:10.1016/j.ejim.2021.10.032 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 15, 2021 Category: Internal Medicine Authors: Stefano Ricci Danilo Toni Mauro Silvestrini Source Type: research

Optimal duration of anticoagulation therapy for venous thromboembolism in autoimmune diseases
Eur J Intern Med. 2021 Nov 9:S0953-6205(21)00376-9. doi: 10.1016/j.ejim.2021.11.001. Online ahead of print.NO ABSTRACTPMID:34772599 | DOI:10.1016/j.ejim.2021.11.001 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 13, 2021 Category: Internal Medicine Authors: Yugo Yamashita Takeshi Morimoto Takeshi Kimura Source Type: research

Drug-induced liver injury: Pathogenesis, epidemiology, clinical features, and practical management
Eur J Intern Med. 2021 Nov 9:S0953-6205(21)00375-7. doi: 10.1016/j.ejim.2021.10.035. Online ahead of print.ABSTRACTDrug-induced liver injury (DILI) is an important but rare adverse event which can range from mild liver enzyme elevations to liver failure, transplantation or death. A large proportion of commonly used medications, in addition to herbal and dietary supplements, can cause liver injury. DILI has been categorized as direct or idiosyncratic but indirect liver injury has emerged as a third type of drug-induced liver injury. These types of liver injury may warrant different clinical approach and treatment. Associati...
Source: European Journal of Internal Medicine - November 13, 2021 Category: Internal Medicine Authors: H K Bj örnsson E S Bj örnsson Source Type: research

Optimal duration of anticoagulation therapy for venous thromboembolism in autoimmune diseases
Eur J Intern Med. 2021 Nov 9:S0953-6205(21)00376-9. doi: 10.1016/j.ejim.2021.11.001. Online ahead of print.NO ABSTRACTPMID:34772599 | DOI:10.1016/j.ejim.2021.11.001 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 13, 2021 Category: Internal Medicine Authors: Yugo Yamashita Takeshi Morimoto Takeshi Kimura Source Type: research

Drug-induced liver injury: Pathogenesis, epidemiology, clinical features, and practical management
Eur J Intern Med. 2021 Nov 9:S0953-6205(21)00375-7. doi: 10.1016/j.ejim.2021.10.035. Online ahead of print.ABSTRACTDrug-induced liver injury (DILI) is an important but rare adverse event which can range from mild liver enzyme elevations to liver failure, transplantation or death. A large proportion of commonly used medications, in addition to herbal and dietary supplements, can cause liver injury. DILI has been categorized as direct or idiosyncratic but indirect liver injury has emerged as a third type of drug-induced liver injury. These types of liver injury may warrant different clinical approach and treatment. Associati...
Source: European Journal of Internal Medicine - November 13, 2021 Category: Internal Medicine Authors: H K Bj örnsson E S Bj örnsson Source Type: research

The prognostic value of malnutrition on duration of admission, financial cost and mortality in elderly, hospitalized patients
Eur J Intern Med. 2021 Nov 8:S0953-6205(21)00374-5. doi: 10.1016/j.ejim.2021.10.034. Online ahead of print.NO ABSTRACTPMID:34763980 | DOI:10.1016/j.ejim.2021.10.034 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 12, 2021 Category: Internal Medicine Authors: Christos E Lampropoulos Maria Konsta Afroditi Roumpou Vicky Dradaki Ioanna Papaioannou Source Type: research

Ankle-brachial index and the risk of hemorrhagic stroke
Eur J Intern Med. 2021 Nov 8:S0953-6205(21)00344-7. doi: 10.1016/j.ejim.2021.10.013. Online ahead of print.NO ABSTRACTPMID:34763981 | DOI:10.1016/j.ejim.2021.10.013 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 12, 2021 Category: Internal Medicine Authors: Lia Alves-Cabratosa Marc Comas-Cuf í Ruth Mart í-Lluch Anna Ponjoan Rafel Ramos Source Type: research

Sepsis-driven atrial fibrillation and ischaemic stroke. Is there enough evidence to recommend anticoagulation?
Eur J Intern Med. 2021 Nov 8:S0953-6205(21)00361-7. doi: 10.1016/j.ejim.2021.10.022. Online ahead of print.ABSTRACTSepsis can lead to cardiac arrhythmias, of which the most common is atrial fibrillation (AF). Sepsis is associated with up to a six-fold higher risk of developing AF, where it occurs most commonly in the first 3 days of hospital admission. In many patients, AF detected during sepsis is the first documented episode of AF, either as an unmasking of sub-clinical AF or as a newly developed arrhythmia. In the short term, sepsis that is complicated by AF leads to longer hospital stays and an increased risk of inpati...
Source: European Journal of Internal Medicine - November 12, 2021 Category: Internal Medicine Authors: Isuru Induruwa Eleanor Hennebry James Hennebry Mrinal Thakur Elizabeth Warburton Kayvan Khadjooi Source Type: research

The prognostic value of malnutrition on duration of admission, financial cost and mortality in elderly, hospitalized patients
Eur J Intern Med. 2021 Nov 8:S0953-6205(21)00374-5. doi: 10.1016/j.ejim.2021.10.034. Online ahead of print.NO ABSTRACTPMID:34763980 | DOI:10.1016/j.ejim.2021.10.034 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 12, 2021 Category: Internal Medicine Authors: Christos E Lampropoulos Maria Konsta Afroditi Roumpou Vicky Dradaki Ioanna Papaioannou Source Type: research

Ankle-brachial index and the risk of hemorrhagic stroke
Eur J Intern Med. 2021 Nov 8:S0953-6205(21)00344-7. doi: 10.1016/j.ejim.2021.10.013. Online ahead of print.NO ABSTRACTPMID:34763981 | DOI:10.1016/j.ejim.2021.10.013 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 12, 2021 Category: Internal Medicine Authors: Lia Alves-Cabratosa Marc Comas-Cuf í Ruth Mart í-Lluch Anna Ponjoan Rafel Ramos Source Type: research

Sepsis-driven atrial fibrillation and ischaemic stroke. Is there enough evidence to recommend anticoagulation?
Eur J Intern Med. 2021 Nov 8:S0953-6205(21)00361-7. doi: 10.1016/j.ejim.2021.10.022. Online ahead of print.ABSTRACTSepsis can lead to cardiac arrhythmias, of which the most common is atrial fibrillation (AF). Sepsis is associated with up to a six-fold higher risk of developing AF, where it occurs most commonly in the first 3 days of hospital admission. In many patients, AF detected during sepsis is the first documented episode of AF, either as an unmasking of sub-clinical AF or as a newly developed arrhythmia. In the short term, sepsis that is complicated by AF leads to longer hospital stays and an increased risk of inpati...
Source: European Journal of Internal Medicine - November 12, 2021 Category: Internal Medicine Authors: Isuru Induruwa Eleanor Hennebry James Hennebry Mrinal Thakur Elizabeth Warburton Kayvan Khadjooi Source Type: research

Disguised aspects of IgG4
Eur J Intern Med. 2021 Oct 27:S0953-6205(21)00355-1. doi: 10.1016/j.ejim.2021.10.016. Online ahead of print.NO ABSTRACTPMID:34756504 | PMC:PMC8549607 | DOI:10.1016/j.ejim.2021.10.016 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 10, 2021 Category: Internal Medicine Authors: Natalia Aleksandra Du łak Rafa ł Trzciński Source Type: research

Long COVID: A patient perspective
Eur J Intern Med. 2021 Oct 28:S0953-6205(21)00364-2. doi: 10.1016/j.ejim.2021.10.023. Online ahead of print.NO ABSTRACTPMID:34756631 | PMC:PMC8553650 | DOI:10.1016/j.ejim.2021.10.023 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 10, 2021 Category: Internal Medicine Authors: S Harari L Ripamonti P Marveggio P M Mannucci Source Type: research

Disguised aspects of IgG4
Eur J Intern Med. 2021 Oct 27:S0953-6205(21)00355-1. doi: 10.1016/j.ejim.2021.10.016. Online ahead of print.NO ABSTRACTPMID:34756504 | DOI:10.1016/j.ejim.2021.10.016 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 10, 2021 Category: Internal Medicine Authors: Natalia Aleksandra Du łak Rafa ł Trzciński Source Type: research

Long COVID: A patient perspective
Eur J Intern Med. 2021 Oct 28:S0953-6205(21)00364-2. doi: 10.1016/j.ejim.2021.10.023. Online ahead of print.NO ABSTRACTPMID:34756631 | DOI:10.1016/j.ejim.2021.10.023 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 10, 2021 Category: Internal Medicine Authors: S Harari L Ripamonti P Marveggio P M Mannucci Source Type: research

Hydroxichloroquine for COVID-19 infection: Do we have a final word after one year?
Eur J Intern Med. 2021 Oct 26:S0953-6205(21)00366-6. doi: 10.1016/j.ejim.2021.10.026. Online ahead of print.ABSTRACTThe results presently available from randomised clinical trials and their meta-analysis indicate that Hydroxychloroquine is not associated in COVID-19 patients with either decreased mortality or clinical worsening. Thus, the use of Hydroxychloroquine in COVID-19 patients cannot at present be encouraged. However, the hypothesis that Hydroxychloroquine might have a beneficial role in subgroups of patients at low risk and/or when used at low dosage (≤ 400 mg/day) deserves to be tested in large, well designed ...
Source: European Journal of Internal Medicine - November 9, 2021 Category: Internal Medicine Authors: Augusto Di Castelnuovo Simona Costanzo Alessandro Gialluisi Licia Iacoviello Giovanni de Gaetano Source Type: research

Hydroxichloroquine for COVID-19 infection: Do we have a final word after one year?
Eur J Intern Med. 2021 Oct 26:S0953-6205(21)00366-6. doi: 10.1016/j.ejim.2021.10.026. Online ahead of print.ABSTRACTThe results presently available from randomised clinical trials and their meta-analysis indicate that Hydroxychloroquine is not associated in COVID-19 patients with either decreased mortality or clinical worsening. Thus, the use of Hydroxychloroquine in COVID-19 patients cannot at present be encouraged. However, the hypothesis that Hydroxychloroquine might have a beneficial role in subgroups of patients at low risk and/or when used at low dosage (≤ 400 mg/day) deserves to be tested in large, well designed ...
Source: European Journal of Internal Medicine - November 9, 2021 Category: Internal Medicine Authors: Augusto Di Castelnuovo Simona Costanzo Alessandro Gialluisi Licia Iacoviello Giovanni de Gaetano Source Type: research

Humoral SARS-COV-2 IgG decay within 6 months in COVID-19 healthy vaccinees: The need for a booster vaccine dose?
Eur J Intern Med. 2021 Oct 27:S0953-6205(21)00362-9. doi: 10.1016/j.ejim.2021.10.027. Online ahead of print.NO ABSTRACTPMID:34742628 | DOI:10.1016/j.ejim.2021.10.027 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 7, 2021 Category: Internal Medicine Authors: Anat Achiron Mathilda Mandel Sapir Dreyer-Alster Gil Harari Michael Gurevich Source Type: research

Humoral SARS-COV-2 IgG decay within 6 months in COVID-19 healthy vaccinees: The need for a booster vaccine dose?
Eur J Intern Med. 2021 Oct 27:S0953-6205(21)00362-9. doi: 10.1016/j.ejim.2021.10.027. Online ahead of print.NO ABSTRACTPMID:34742628 | DOI:10.1016/j.ejim.2021.10.027 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 7, 2021 Category: Internal Medicine Authors: Anat Achiron Mathilda Mandel Sapir Dreyer-Alster Gil Harari Michael Gurevich Source Type: research

The high-risk bleeding category of different scores in patients with venous thromboembolism: Systematic review and meta-analysis
Eur J Intern Med. 2021 Nov 1:S0953-6205(21)00353-8. doi: 10.1016/j.ejim.2021.10.014. Online ahead of print.ABSTRACTBACKGROUND: In patients with venous thromboembolism (VTE), bleeding risk should be carefully assessed but none of the available risk scores is currently recommended. The aim of this study was to systematically evaluate the performance of bleeding scores in patients with VTE focusing on high-risk patients.METHODS: Longitudinal studies were searched in Medline and Cochrane Library, as well as reviews and references of retrieved articles. Studies were identified, data were extracted, and reporting quality was eva...
Source: European Journal of Internal Medicine - November 4, 2021 Category: Internal Medicine Authors: Miguel Marques Antunes Mariana Alves Fausto J Pinto Giancarlo Agnelli Daniel Caldeira Source Type: research

The high-risk bleeding category of different scores in patients with venous thromboembolism: Systematic review and meta-analysis
Eur J Intern Med. 2021 Nov 1:S0953-6205(21)00353-8. doi: 10.1016/j.ejim.2021.10.014. Online ahead of print.ABSTRACTBACKGROUND: In patients with venous thromboembolism (VTE), bleeding risk should be carefully assessed but none of the available risk scores is currently recommended. The aim of this study was to systematically evaluate the performance of bleeding scores in patients with VTE focusing on high-risk patients.METHODS: Longitudinal studies were searched in Medline and Cochrane Library, as well as reviews and references of retrieved articles. Studies were identified, data were extracted, and reporting quality was eva...
Source: European Journal of Internal Medicine - November 4, 2021 Category: Internal Medicine Authors: Miguel Marques Antunes Mariana Alves Fausto J Pinto Giancarlo Agnelli Daniel Caldeira Source Type: research