miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1
Prostate cancer (PCa) is one of the most common types of cancer in men. In the course of the development and progression of this disease, abnormal expression of miR-203 is usually accompanied. However, its rol... (Source: BMC Cancer)
Source: BMC Cancer - October 27, 2020 Category: Cancer & Oncology Authors: Yang Meng, Xiaoyan Hu, Shasha Li, Xinyi Zeng, Lei Qiu, Mingtian Wei, Ziqing Wang and Junhong Han Tags: Research article Source Type: research

An integrated autophagy-related gene signature predicts prognosis in human endometrial Cancer
Globally, endometrial cancer is the fourth most common malignant tumor in women and the number of women being diagnosed is increasing. Tumor progression is strongly related to the cell survival-promoting funct... (Source: BMC Cancer)
Source: BMC Cancer - October 27, 2020 Category: Cancer & Oncology Authors: Jun Zhang, Ziwei Wang, Rong Zhao, Lanfen An, Xing Zhou, Yingchao Zhao and Hongbo Wang Tags: Research article Source Type: research

High expression of fibroblast activation protein (FAP) predicts poor outcome in high-grade serous ovarian cancer
High-grade serous ovarian cancer (HGSOC) is a fatal form of ovarian cancer. Previous studies indicated some potential biomarkers for clinical evaluation of HGSOC prognosis. However, there is a lack of systemat... (Source: BMC Cancer)
Source: BMC Cancer - October 27, 2020 Category: Cancer & Oncology Authors: Min Li, Xue Cheng, Rong Rong, Yan Gao, Xiuwu Tang and Youguo Chen Tags: Research article Source Type: research

Is it the time to implement the routine use of distress thermometer among Egyptian patients with newly diagnosed cancer?
The distress thermometer (DT) is an effective tool for identifying distress among cancer patients worldwide. However, DT has not been studied in Egyptian patients. We aimed to study the prevalence of distress ... (Source: BMC Cancer)
Source: BMC Cancer - October 27, 2020 Category: Cancer & Oncology Authors: Nashwa Abd El-Aziz, Salah Khallaf, Waleed Abozaid, Ghada Elgohary, Ola Abd El-Fattah, Mai Alhawari, Safaa Khaled, Azza AbdelHaffez, Ehab Kamel and Sherif Mohamed Tags: Research article Source Type: research

Impact of submandibular gland preservation in neck management of early-stage buccal squamous cell carcinoma on locoregional control and disease-specific survival
The feasibility of submandibular gland (SMG) preservation in oral squamous cell carcinoma (SCC) has occasionally been analyzed, but the differences in survival associated with the presence or absence of SMG pr... (Source: BMC Cancer)
Source: BMC Cancer - October 27, 2020 Category: Cancer & Oncology Authors: Bo Gu, Qigen Fang, Yao Wu, Wei Du, Xu Zhang and Defeng Chen Tags: Research article Source Type: research

Correction to: Analysis of the role of the human papillomavirus 16/18 E7 protein assay in screening for cervical intraepithelial neoplasia: a case control study
An amendment to this paper has been published and can be accessed via the original article. (Source: BMC Cancer)
Source: BMC Cancer - October 26, 2020 Category: Cancer & Oncology Authors: Linghua Kong, Xiaoping Xiao, Huiping Lou, Pengfei Liu, Shuhui Song, Moudu Liu, Tao Xu, Ying Zhang, Caijuan Li, Ruoli Guan, Yan Li, Xin Yu, Haiyuan Liu, Qingbo Fan, Honghui Shi and Lan Zhu Tags: Correction Source Type: research

Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells
For most patients, pancreatic adenocarcinoma responds poorly to treatment, and novel therapeutic approaches are needed. Standard-of-care paclitaxel (PTX), combined with birinapant (BRP), a bivalent mimetic of ... (Source: BMC Cancer)
Source: BMC Cancer - October 23, 2020 Category: Cancer & Oncology Authors: Jin Niu, Xue Wang, Jun Qu, Donald E. Mager and Robert M. Straubinger Tags: Research article Source Type: research

14-type HPV mRNA test in triage of HPV DNA-positive postmenopausal women with normal cytology
During 2013 and 2016 the region of Sk åne, Sweden started to analyse human papillomavirus (HPV) and cytology in postmenopausal women 60–65 years of age. Our aim was to evaluate high-risk (HR) HPV mRNA testing f... (Source: BMC Cancer)
Source: BMC Cancer - October 23, 2020 Category: Cancer & Oncology Authors: Katrin Christine Asciutto, Christer Borgfeldt and Ola Forslund Tags: Research article Source Type: research

Circular RNA hsa_circ_0000282 contributes to osteosarcoma cell proliferation by regulating miR-192/XIAP axis
Circular RNAs (circRNAs) have emerged as a novel category of non-coding RNA, which exhibit a pivotal effect on regulating gene expression and biological functions, yet how circRNAs function in osteosarcoma (OS... (Source: BMC Cancer)
Source: BMC Cancer - October 23, 2020 Category: Cancer & Oncology Authors: Houkun Li, Limin He, Yuan Tuo, Yansheng Huang and Bing Qian Tags: Research article Source Type: research

Artificial neural networks improve LDCT lung cancer screening: a comparative validation study
This study proposes a prediction model for the automatic assessment of lung cancer risk based on an artificial neural network (ANN) with a data-driven approach to the low-dose computed tomography (LDCT) standa... (Source: BMC Cancer)
Source: BMC Cancer - October 22, 2020 Category: Cancer & Oncology Authors: Yin-Chen Hsu, Yuan-Hsiung Tsai, Hsu-Huei Weng, Li-Sheng Hsu, Ying-Huang Tsai, Yu-Ching Lin, Ming-Szu Hung, Yu-Hung Fang and Chien-Wei Chen Tags: Research article Source Type: research

The association between immune-related adverse events and survival outcomes in Asian patients with advanced melanoma receiving anti-PD-1 antibodies
The association between immune-related adverse events (irAEs) and survival outcomes in patients with advanced melanoma receiving therapy with immune checkpoint inhibitors (ICIs) has not been well established, ... (Source: BMC Cancer)
Source: BMC Cancer - October 21, 2020 Category: Cancer & Oncology Authors: Chiao-En Wu, Chan-Keng Yang, Meng-Ting Peng, Pei-Wei Huang, Ching-Fu Chang, Kun-Yun Yeh, Chun-Bing Chen, Chih-Liang Wang, Chao-Wei Hsu, I-Wen Chen, Cheng-Tao Lin, Shir-Hwa Ueng, Gigin Lin, Yu-Fen Lin, Chi-Yuan Cheng and John Wen-Cheng Chang Tags: Research article Source Type: research

microRNA-451a promoter methylation regulated by DNMT3B expedites bladder cancer development via the EPHA2/PI3K/AKT axis
The downregulation of microRNA (miR)-451a has been reported in bladder cancer (BCa) tissues. Herein, we elucidated the role of miR-451a in BCa with the involvement of DNA methyltransferase 3B (DNMT3B). (Source: BMC Cancer)
Source: BMC Cancer - October 21, 2020 Category: Cancer & Oncology Authors: Beibei Liu, Wei Sun, Wuyue Gao, Liqiang Li, Zhenxue Cao, Xiaohuai Yang, Jianmin Liu and Yuanyuan Guo Tags: Research article Source Type: research

Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium
Loss of the genomic stability jeopardize genome stability and promote malignancies. A fraction of ovarian cancer (OvCa) arises from pathological mutations of DNA repair genes that result in highly mutagenic ge... (Source: BMC Cancer)
Source: BMC Cancer - October 21, 2020 Category: Cancer & Oncology Authors: Liang Song, Zizhi Tang, Changsheng Peng, Yueming Yang, Chang Guo, Danqing Wang, Liandi Guo, Jie Chen and Cong Liu Tags: Research article Source Type: research

Endostar continuous versus intermittent intravenous infusion combined with chemotherapy for advanced NSCLC: a systematic review and meta-analysis including non-randomized studies
Both intermittent intravenous (IIV) infusion and continuous intravenous (CIV) infusion of Endostar are widely used for NSCLC in China. We aimed to compare the efficacy and safety of CIV of Endostar versus IIV ... (Source: BMC Cancer)
Source: BMC Cancer - October 21, 2020 Category: Cancer & Oncology Authors: Bo Wang, Lu Xu, Qihuan Li, Sailimai Man, Cheng Jin, Lian Liu, Siyan Zhan and Yi Ning Tags: Research article Source Type: research

Tumor infiltrating immune cells (TIICs) as a biomarker for prognosis benefits in patients with osteosarcoma
Osteosarcoma is a rare malignant bone tumor in adolescents and children. Poor prognosis has always been a difficult problem for patients with osteosarcoma. Recent studies have shown that tumor infiltrating imm... (Source: BMC Cancer)
Source: BMC Cancer - October 21, 2020 Category: Cancer & Oncology Authors: Ying Chen, Bo Zhao and Xiaohu Wang Tags: Research article Source Type: research

Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer
Peritoneal metastasis (PM) in gastric cancer (GC) is characterized by diffusely infiltrating and proliferating cancer cells accompanied by extensive stromal fibrosis in the peritoneal space. The prognosis of G... (Source: BMC Cancer)
Source: BMC Cancer - October 20, 2020 Category: Cancer & Oncology Authors: Daisuke Fujimori, Jun Kinoshita, Takahisa Yamaguchi, Yusuke Nakamura, Katsuya Gunjigake, Takashi Ohama, Koichi Sato, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Tetsuo Ohta and Sachio Fushida Tags: Research article Source Type: research

Development and validation of a fourteen- innate immunity-related gene pairs signature for predicting prognosis head and neck squamous cell carcinoma
Immune-related genes is closely related to the occurrence and prognosis of head and neck squamous cell carcinoma (HNSCC). At the same time, immune-related genes have great potential as prognostic markers in ma... (Source: BMC Cancer)
Source: BMC Cancer - October 20, 2020 Category: Cancer & Oncology Authors: Fujun Zhang, Yu Liu, Yixin Yang and Kai Yang Tags: Research article Source Type: research

An immunochemistry-based screen for chemical inhibitors of DNA-protein interactions and its application to human CGGBP1
Inhibition of DNA-binding of proteins by small-molecule chemicals holds immense potential in manipulating the activities of DNA-binding proteins. Such a chemical inhibition of DNA-binding of proteins can be us... (Source: BMC Cancer)
Source: BMC Cancer - October 20, 2020 Category: Cancer & Oncology Authors: Manthan Patel, Divyesh Patel, Subhamoy Datta and Umashankar Singh Tags: Technical advance Source Type: research

A Swedish Nationwide prospective study of oncological and reproductive outcome following fertility-sparing surgery for treatment of early stage epithelial ovarian cancer in young women
Epithelial ovarian cancer (EOC) is rare in women of reproductive age and fertility-sparing surgery (FSS) may be applied in early stages. The purpose of this study was to investigate the safety and efficacy of ... (Source: BMC Cancer)
Source: BMC Cancer - October 19, 2020 Category: Cancer & Oncology Authors: Gry Johansen, Pernilla Dahm-K ähler, Christian Staf, Angelique Flöter Rådestad and Kenny A. Rodriguez-Wallberg Tags: Research article Source Type: research

Presence of dynapenia and association with anthropometric variables in cancer patients
Dynapenia is defined as an age-related loss of muscle strength. There is little information on dynapenia in cancer patients and on how it relates to anthropometric variables. The aim of this study was to analy... (Source: BMC Cancer)
Source: BMC Cancer - October 19, 2020 Category: Cancer & Oncology Authors: Ana Beatriz Rechinelli, Isabele Lessa Marques, Eduarda Cristina Rodrigues de Morais Viana, Isadora da Silva Oliveira, Vanusa Fel ício de Souza, Glenda Blaser Petarli, Jose Luiz Marques Rocha and Valdete Regina Guandalini Tags: Research article Source Type: research

Seeking healthcare at their ‘right’ time; the iterative decision process for women with breast cancer
About 85% of breast cancer patients attending Komfo Anokye Teaching Hospital (KATH), Ghana, present with stage III/IV disease. In spite of great investments into the early diagnosis and management of breast ca... (Source: BMC Cancer)
Source: BMC Cancer - October 19, 2020 Category: Cancer & Oncology Authors: Anita Eseenam Agbeko, Joshua Arthur, Jonathan Bayuo, Basil Benduri Kaburi and Ishmael Kyei Tags: Research article Source Type: research

Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods
In recent years, the differences between left-sided colon cancer (LCC) and right-sided colon cancer (RCC) have received increasing attention due to the clinicopathological variation between them. However, some... (Source: BMC Cancer)
Source: BMC Cancer - October 19, 2020 Category: Cancer & Oncology Authors: Yimei Jiang, Xiaowei Yan, Kun Liu, Yiqing Shi, Changgang Wang, Jiele Hu, You Li, Qinghua Wu, Ming Xiang and Ren Zhao Tags: Research article Source Type: research

Longitudinal changes in sports activity from pre-diagnosis to first five years post-diagnosis: a prospective Chinese breast cancer cohort study
To compare change in level of physical activity between pre-and post- diagnosis of breast cancer in Chinese women. (Source: BMC Cancer)
Source: BMC Cancer - October 19, 2020 Category: Cancer & Oncology Authors: Yuan-Yuan Lei, Suzanne C. Ho, Carol Kwok, Ashley Cheng, Ka Li Cheung, Roselle Lee and Winnie Yeo Tags: Research article Source Type: research

Inducing multiple antibodies to treat squamous cell esophageal carcinoma
The positive response and the clinical usefulness of 14 serum antibodies in patients with esophageal squamous cell carcinoma (ESCC) were examined in this study. The Cancer Genome Atlas (TCGA) was used to inves... (Source: BMC Cancer)
Source: BMC Cancer - October 17, 2020 Category: Cancer & Oncology Authors: Isamu Hoshino, Yoshihiro Nabeya, Nobuhiro Takiguchi, Hisashi Gunji, Fumitaka Ishige, Yosuke Iwatate, Akiko Kuwajima, Fumiaki Shiratori, Rei Okada and Hideaki Shimada Tags: Research article Source Type: research

Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway
Alternatively-activated macrophages (AAMs), an anti-inflammatory macrophage subpopulation, have been implicated in the progression of high grade serous ovarian carcinoma (HGSOC). Increased levels of AAMs are c... (Source: BMC Cancer)
Source: BMC Cancer - October 17, 2020 Category: Cancer & Oncology Authors: Kaitlin C. Fogg, Andrew E. Miller, Ying Li, Will Flanigan, Alyssa Walker, Andrea O ’Shea, Christina Kendziorski and Pamela K. Kreeger Tags: Research article Source Type: research

Role of circulating free DNA in evaluating clinical tumor burden and predicting survival in Chinese metastatic colorectal cancer patients
The aim of this study was to explore the utility of circulating free DNA (cfDNA) in the evaluation of clinical tumor burden and survival in Chinese patients with metastatic colorectal cancer (mCRC) and to prel... (Source: BMC Cancer)
Source: BMC Cancer - October 16, 2020 Category: Cancer & Oncology Authors: Xiaojing Xu, Yiyi Yu, Minna Shen, Mengling Liu, Shengchao Wu, Li Liang, Fei Huang, Chenlu Zhang, Wei Guo and Tianshu Liu Tags: Research article Source Type: research

Detection of MCM5 as a novel non-invasive aid for the diagnosis of endometrial and ovarian tumours
MCM5 is a protein involved in DNA replication, facilitating cell proliferation. In normal epithelium MCM5 expression is restricted to the cells in the basal proliferative compartments, however in the presence ... (Source: BMC Cancer)
Source: BMC Cancer - October 15, 2020 Category: Cancer & Oncology Authors: J. Stockley, R. Akhand, A. Kennedy, C. Nyberg, E. J. Crosbie and R. J. Edmondson Tags: Research article Source Type: research

CKD-5, a novel pan-histone deacetylase inhibitor, synergistically enhances the efficacy of sorafenib for hepatocellular carcinoma
Histone deacetylase inhibitors (HDACIs) have distinctive epigenetic targets involved in hepatocarcinogenesis and chemoresistance. A recent phase I/II study reported the possibility of HDACI as a chemosensitize... (Source: BMC Cancer)
Source: BMC Cancer - October 15, 2020 Category: Cancer & Oncology Authors: Young Chang, Yun Bin Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim and Jung-Hwan Yoon Tags: Research article Source Type: research

Biomarker exploration of microRNA-203 as a promising substrate for predicting poor survival outcome in colorectal cancer
Increasing studies indicated that microRNA-203 (miR-203) may play an important part in the prognosis of CRC. Nevertheless, the prognostic and influential mechanism of miR-203 expression in CRC remains to be in... (Source: BMC Cancer)
Source: BMC Cancer - October 15, 2020 Category: Cancer & Oncology Authors: Qiliang Peng, Yi Shen, Peifeng Zhao, Shang Cai, Zhengyang Feng, Ming Cheng, Yongyou Wu and Yaqun Zhu Tags: Research article Source Type: research

Impact of pre-existing cardiovascular disease on treatment patterns and survival outcomes in patients with lung cancer
This study aimed to characterize treatment trends and survival outcomes of patien... (Source: BMC Cancer)
Source: BMC Cancer - October 15, 2020 Category: Cancer & Oncology Authors: Atul Batra, Dropen Sheka, Shiying Kong and Winson Y. Cheung Tags: Research article Source Type: research

CircRNAs as potential biomarkers for the clinicopathology and prognosis of glioma patients: a meta-analysis
An increasing number of studies have reported circular RNAs (circRNAs) as new potential biomarkers for the prognosis of gliomas. However, the overall prognostic value of circRNAs for glioma remains unclear. Th... (Source: BMC Cancer)
Source: BMC Cancer - October 15, 2020 Category: Cancer & Oncology Authors: Xiangqian Ding, Luyao Yang, Xin Geng, Yanghong Zou, Zhigang Wang, Yao Li, Renli Qi, Wei Wang, Jinghui Li and Hualin Yu Tags: Research article Source Type: research

Clinical characteristics and prognostic implications of BRCA-associated tumors in males: a pan-tumor survey
The BRCA mutation (BRCAm) in males has been reported to confer a higher risk for the development of various tumors. However, little is known about its clinicopathologic features and prognostic implications. (Source: BMC Cancer)
Source: BMC Cancer - October 14, 2020 Category: Cancer & Oncology Authors: Peng Sun, Yue Li, Xue Chao, Jibin Li, Rongzhen Luo, Mei Li and Jiehua He Tags: Research article Source Type: research

Limb salvage versus amputation in patients with osteosarcoma of the extremities: an update in the modern era using the National Cancer Database
Historically, amputation was the primary surgical treatment for osteosarcoma of the extremities; however, with advancements in surgical techniques and chemotherapies limb salvage has replaced amputation as the... (Source: BMC Cancer)
Source: BMC Cancer - October 14, 2020 Category: Cancer & Oncology Authors: Daniel R. Evans, Alexander L. Lazarides, Julia D. Visgauss, Jason A. Somarelli, Dan G. Blazer III, Brian E. Brigman and William C. Eward Tags: Research article Source Type: research

YB-1 transferred by gastric cancer exosomes promotes angiogenesis via enhancing the expression of angiogenic factors in vascular endothelial cells
Angiogenesis is important for the progression of gastric cancer (GC). Y-box binding protein 1 (YB-1) predicts advanced disease and indicates neovasculature formation in GC tissues, while the related mechanisms... (Source: BMC Cancer)
Source: BMC Cancer - October 14, 2020 Category: Cancer & Oncology Authors: Xiaoxia Xue, Jin Huang, Kai Yu, Xinyue Chen, Yini He, Dianjun Qi and Ying Wu Tags: Research article Source Type: research

USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer
Triple-negative breast cancer (TNBC), in part because of the high metastasis rate, is one of the most prevalent causes of malignancy-related mortality globally. Ubiquitin specific peptidase 6  N-terminal like (... (Source: BMC Cancer)
Source: BMC Cancer - October 14, 2020 Category: Cancer & Oncology Authors: Teng Ma, Huaidong Liu, Yan Liu, Tingting Liu, Hui Wang, Fulu Qiao, Lu Song and Lin Zhang Tags: Research article Source Type: research

Analysis of the role of the human papillomavirus 16/18 E7 protein assay in screening for cervical intraepithelial neoplasia: a case control study
Cervical cancer is the second-most common gynecological cancer, early screening plays a key role in the diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Sustained E7 protein expression is t... (Source: BMC Cancer)
Source: BMC Cancer - October 14, 2020 Category: Cancer & Oncology Authors: Linghua Kong, Xiaoping Xiao, Huiping Lou, Pengfei Liu, Shuhui Song, Moudu Liu, Tao Xu, Ying Zhang, Caijuan Li, Ruoli Guan, Yan Li, Xin Yu, Haiyuan Liu, Qingbo Fan, Honghui Shi and Lan Zhu Tags: Research article Source Type: research

Cost-effectiveness analysis of fruquintinib for metastatic colorectal cancer third-line treatment in China
In this study, we analyze the cost-effectiveness of fruquintinib as third-line treatment for patients with metastatic colorectal cancer in China, especially after a recent price drop suggested by the National ... (Source: BMC Cancer)
Source: BMC Cancer - October 13, 2020 Category: Cancer & Oncology Authors: Zhi Peng, Xingduo Hou, Yangmu Huang, Tong Xie and Xinyang Hua Tags: Research article Source Type: research

Impact of concomitant systemic treatments on toxicity and intracerebral response after stereotactic radiotherapy for brain metastases
The aim of this study was to determine the safety and efficacy of fractionated stereotactic radiotherapy (SRT) in combination with systemic therapies (ST) for brain metastases (BM). (Source: BMC Cancer)
Source: BMC Cancer - October 13, 2020 Category: Cancer & Oncology Authors: Morgan Gu énolé, François Lucia, Vincent Bourbonne, Gurvan Dissaux, Emmanuelle Reygagne, Gaëlle Goasduff, Olivier Pradier and Ulrike Schick Tags: Research article Source Type: research

Cost-effectiveness of brentuximab vedotin in advanced stage Hodgkin ’s lymphoma: a probabilistic analysis
Treatment with ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is a well-established therapy for advanced Hodgkin ’s lymphoma (HL). However, the recently completed ECHELON-1 trial showed potential n... (Source: BMC Cancer)
Source: BMC Cancer - October 13, 2020 Category: Cancer & Oncology Authors: A. J. N. Raymakers, S. Costa, D. Cameron and D. A. Regier Tags: Research article Source Type: research

A nomogram for predicting survival in patients with de novo metastatic breast cancer: a population-based study
This study aimed to develop a nomogram to predict the overall survival (OS) of these patients. (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2020 Category: Cancer & Oncology Authors: Wen Zhao, Lei Wu, Andi Zhao, Mi Zhang, Qi Tian, Yanwei Shen, Fan Wang, Biyuan Wang, Le Wang, Ling Chen, Xiaoai Zhao, Danfeng Dong, Lingxiao Zhang and Jin Yang Tags: Research article Source Type: research

Cancer in Moroccan elderly: the first multicenter transverse study exploring the sociodemographic characteristics, clinical profile and quality of life of elderly Moroccan cancer patients
Moroccan incidence of cancer is increasing with the lengthening of life expectancy. Data regarding elderly Moroccan cancer patients are lacking. In the context of our project aiming to develop an adapted versi... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2020 Category: Cancer & Oncology Authors: Mounia Amzerin, Mohamed Layachi, Aziz Bazine, Rachid Aassab, Samia Arifi, Zineb Benbrahim, Mohamed Reda Khmamouche, Mouna Kairouani, Hanan Raiss, Noura Majid, Saloua Ouaouch, Mohammed Ichou, Said Afqir, Nawfal Mellas, Mohamed Fetohi, Rachid Razine & helli Tags: Research article Source Type: research

ECCDIA: an interactive web tool for the comprehensive analysis of clinical and survival data of esophageal cancer patients
Esophageal cancer (EC) is considered as one of the deadliest malignancies with respect to incidence and mortality rate, and numerous risk factors may affect the prognosis of EC patients. For better understandi... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2020 Category: Cancer & Oncology Authors: Jingcheng Yang, Jun Shang, Qian Song, Zuyi Yang, Jianing Chen, Ying Yu and Leming Shi Tags: Technical advance Source Type: research

The Axin2-snail axis promotes bone invasion by activating cancer-associated fibroblasts in oral squamous cell carcinoma
In bone-invasive oral squamous cell carcinoma (OSCC), cancer-associated fibroblasts (CAFs) infiltrate into bony tissue ahead of OSCC cells. In the present study, we aimed to investigate the role of the Axin2-S... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2020 Category: Cancer & Oncology Authors: Yin-Zhe An, Eunae Cho, Junqi Ling and Xianglan Zhang Tags: Research article Source Type: research

Relationship between formulaic breast volume and risk of breast cancer based on linear measurements
This study aimed to evaluate whether a significant association between breast volume and risk of breast cancer, based on linear measur... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2020 Category: Cancer & Oncology Authors: Xiaoxia Li, Chunlan Zhou, Yanni Wu and Xiaohong Chen Tags: Research article Source Type: research

The prognostic significance of inflammation-based scores in patients with ampullary carcinoma after pancreaticoduodenectomy
Growing evidence indicates that the systemic inflammatory response plays an important role in cancer development and progression. Several inflammatory markers have been reported to be associated with clinical ... (Source: BMC Cancer)
Source: BMC Cancer - October 10, 2020 Category: Cancer & Oncology Authors: Shuxin Sun, Chaobin He, Jun Wang, Xin Huang, Jiali Wu and Shengping Li Tags: Research article Source Type: research

Genetic variants in MIR17HG affect the susceptibility and prognosis of glioma in a Chinese Han population
lncRNA MIR17HG was upregulated in glioma, and participated in promoting proliferation, migration and invasion of glioma. However, the role of MIR17HG polymorphisms in the occurrence and prognosis of glioma is sti... (Source: BMC Cancer)
Source: BMC Cancer - October 9, 2020 Category: Cancer & Oncology Authors: Jigao Feng, Yibin Ouyang, Dedong Xu, Qinglong He, Dayuan Liu, Xudong Fan, Pengxiang Xu and Yehe Mo Tags: Research article Source Type: research

Clinical and imaging characteristics of primary hepatic sarcomatoid carcinoma and sarcoma: a comparative study
Primary hepatic sarcomatous carcinoma (PHSC) and primary hepatic sarcoma (PHS) are rare malignancies with frequent overlap in both the clinic and radiology. No comparative study of these tumors for the restric... (Source: BMC Cancer)
Source: BMC Cancer - October 9, 2020 Category: Cancer & Oncology Authors: Dongli Shi, Jun Sun, Liang Ma, Jing Chang and Hongjun Li Tags: Research article Source Type: research

Is hypofractionated whole pelvis radiotherapy (WPRT) as well tolerated as conventionally fractionated WPRT in prostate cancer patients? The HOPE trial
Patients with high-risk prostate cancer are at increased risk of lymph node metastasis and are thought to benefit from whole pelvis radiotherapy (WPRT). There has been recent interest in the use of hypofractio... (Source: BMC Cancer)
Source: BMC Cancer - October 9, 2020 Category: Cancer & Oncology Authors: Lucas C. Mendez, Andrew J. Arifin, Glenn S. Bauman, Vikram M. Velker, Belal Ahmad, Michael Lock, Varagur M. Venkatesan, Tracy L. Sexton, George B. Rodrigues, Jeff Chen, Bryan Schaly, Andrew Warner and David P. D ’Souza Tags: Study protocol Source Type: research

Treatment outcome and long-term follow-up of central nervous system germ cell tumor using upfront chemotherapy with subsequent photon or proton radiation therapy: a single tertiary center experience of 127 patients
Central nervous system germ cell tumors (CNS GCTs) are a heterogeneous group of brain tumors, which are more common in Asian countries. There have been different therapeutic strategies in treating germinoma an... (Source: BMC Cancer)
Source: BMC Cancer - October 9, 2020 Category: Cancer & Oncology Authors: Kyung Taek Hong, Da Hye Lee, Bo Kyung Kim, Hong Yul An, Jung Yoon Choi, Ji Hoon Phi, Jung-Eun Cheon, Hyoung Jin Kang, Seung-Ki Kim, Joo-Young Kim, Sung-Hye Park, Il Han Kim and Hee Young Shin Tags: Research article Source Type: research

Impact of pre-OP independence in patients with limited brain metastases on long-term survival
Brain metastasis represents a major complication with a significantly shorter overall survival of many oncological diseases, in particular of lung cancer, breast cancer and malignant melanoma patients. However... (Source: BMC Cancer)
Source: BMC Cancer - October 8, 2020 Category: Cancer & Oncology Authors: Annalen Bleckmann, Benjamin Kirchner, Manuel Nietert, Micha Peeck, Marko Balkenhol, Daniela Egert, T. Veit Rohde, Tim Bei ßbarth and Tobias Pukrop Tags: Research article Source Type: research