Prognostic influence of endoscopic ultrasound-guided fine needle aspiration in IPMN-derived invasive adenocarcinoma
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for mucinous cystic neoplasm of the pancreas carries a potential risk of inducing peritoneal tumor cell dissemination. We investigated the diagnost... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2018 Category: Cancer & Oncology Authors: Rei Suzuki, Hiroki Irie, Tadayuki Takagi, Mitsuru Sugimoto, Naoki Konno, Yuki Sato, Ko Watanabe, Jun Nakamura, Shigeru Marubashi, Takuto Hikichi and Hiromasa Ohira Tags: Research article Source Type: research

Normalization of abnormal plasma amino acid profile-based indexes in patients with gynecological malignant tumors after curative treatment
In this study, we aimed to evaluate whether abnormal API values could be normaliz... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2018 Category: Cancer & Oncology Authors: Yukio Suzuki, Aya Tokinaga-Uchiyama, Taichi Mizushima, Yasuyo Maruyama, Tae Mogami, Nahoko Shikata, Atsuko Ikeda, Hiroshi Yamamoto and Etsuko Miyagi Tags: Research article Source Type: research

Clinical outcomes comparison of 10 years versus 5 years of adjuvant endocrine therapy in patients with early breast cancer
Adjuvant endocrine therapy undoubtedly prolongs the time to recurrence for patients with hormone-positive early breast cancer. Extended endocrine therapy to 10 years or longer has been expected to bring a grea... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2018 Category: Cancer & Oncology Authors: Li Li, Bingmei Chang, Xiaoyue Jiang, Xueke Fan, Yingrui Li, Teng Li, Shanshan Wu, Jun Zhang, Seyed Kariminia and Qin Li Tags: Research article Source Type: research

Efficacy and safety of concurrent anti-Cancer and anti-tuberculosis chemotherapy in Cancer patients with active Mycobacterium tuberculosis: a retrospective study
In this study, we retrospec... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2018 Category: Cancer & Oncology Authors: Tomonori Hirashima, Yoshitaka Tamura, Yuki Han, Shoji Hashimoto, Ayako Tanaka, Takayuki Shiroyama, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Shinobu Akada, Makoto Fujishima, Yoshihisa Kadota, Kazuya Sakata, Akiko Nishitani, Satoru Miyazaki and Taka Tags: Research article Source Type: research

Expression of fibronectin in esophageal squamous cell carcinoma and its role in migration
Fibronectin (FN) is a high-molecular-weight glycoprotein component of the extracellular matrix involved in cell adhesion, migration, metastasis, proliferation and differentiation, as well as embryogenesis, wou... (Source: BMC Cancer)
Source: BMC Cancer - October 12, 2018 Category: Cancer & Oncology Authors: Jiefei Xiao, Weilin Yang, Bo Xu, Haoshuai Zhu, Jianyong Zou, Chunhua Su, Jian Rong, Tao Wang and Zhenguang Chen Tags: Research article Source Type: research

Optimal cutoff of pretreatment neutrophil-to-lymphocyte ratio in head and neck cancer patients: a meta-analysis and validation study
The prognostic role of neutrophil-to-lymphocyte ratio (NLR) has been proposed in head and neck squamous cell carcinoma (HNSCC). However, it is currently unclear which cutoff values of NLR could consistently an... (Source: BMC Cancer)
Source: BMC Cancer - October 11, 2018 Category: Cancer & Oncology Authors: Jae-Keun Cho, Myoung Woo Kim, Ick Soo Choi, Uk Yeol Moon, Min-Ji Kim, Insuk Sohn, Seonwoo Kim and Han-Sin Jeong Tags: Research article Source Type: research

Coexistence of gastric gastrointestinal stromal tumor, intro-abdominal and retroperitoneal liposarcomas –a case report
Gastric gastrointestinal stromal tumor (GIST), intro-abdominal and retroperitoneal neoplasms are distinct tumors arising from different cell layers; therefore, coexistence of such tumors is relatively rare. (Source: BMC Cancer)
Source: BMC Cancer - October 11, 2018 Category: Cancer & Oncology Authors: Yong Zhou, Xu-Dong Wu, Quan Shi, Chuan-hai Xu and Jing Jia Tags: Case report Source Type: research

A molecular and staging model predicts survival in patients with resected non-small cell lung cancer
In this study, we aim to combine clinical variables and molecular biomar... (Source: BMC Cancer)
Source: BMC Cancer - October 11, 2018 Category: Cancer & Oncology Authors: Lei Liu, Minxin Shi, Zhiwei Wang, Haimin Lu, Chang Li, Yu Tao, Xiaoyan Chen and Jun Zhao Tags: Research article Source Type: research

Osteoporosis development and vertebral fractures after abdominal irradiation in patients with gastric cancer
Decrease in bone mineral density, osteoporosis development, bone toxicity and resulting insufficiency fractures as late effect of radiotherapy are not well known. Osteoporosis development related to radiothera... (Source: BMC Cancer)
Source: BMC Cancer - October 11, 2018 Category: Cancer & Oncology Authors: Gokhan Yaprak, Cengiz Gemici, Sule Temizkan, Sevim Ozdemir, Berfu Cinkit Dogan and Ozgur Ozan Seseogullari Tags: Research article Source Type: research

Post-transcriptional regulation of cancer/testis antigen MAGEC2 expression by TRIM28 in tumor cells
Cancer/testis antigen MAGEC2 (also known as HCA587) is highly expressed in a wide variety of tumors and plays an active role in promoting growth and metastasis of tumor cells. However, little is known for the ... (Source: BMC Cancer)
Source: BMC Cancer - October 11, 2018 Category: Cancer & Oncology Authors: Xiao Song, Chengli Guo, Yutian Zheng, Ying Wang, Zhongtian Jin and Yanhui Yin Tags: Research article Source Type: research

Treatment of colon cancer in a patient with systemic lupus erythematosus: a case report
Gastrointestinal symptoms occur in approximately 50% of patients with systemic lupus erythematous with low specificity. Although it is well established that colon cancer is one of the many gastrointestinal man... (Source: BMC Cancer)
Source: BMC Cancer - October 10, 2018 Category: Cancer & Oncology Authors: Junfeng Shi, Jianquan Fei, Qingqing Yi, Lijuan Shen, Boshun Wan, Yueyu Chen and Qing Chang Tags: Case report Source Type: research

A matched-pair analysis of stereotactic body radiotherapy (SBRT) for oligometastatic lung tumors from colorectal cancer versus early stage non-small cell lung cancer
The use of stereotactic body radiotherapy (SBRT) for early-stage primary non-small cell lung cancer (NSCLC) reported excellent local control rates. But the optimal SBRT dose for oligometastatic lung tumors (OL... (Source: BMC Cancer)
Source: BMC Cancer - October 10, 2018 Category: Cancer & Oncology Authors: Xin Wang, Leonid Zamdborg, Hong Ye, Inga S. Grills and Di Yan Tags: Research article Source Type: research

Genomic analysis of DNA repair genes and androgen signaling in prostate cancer
The cellular effects of androgen are transduced through the androgen receptor, which controls the expression of genes that regulate biosynthetic processes, cell growth, and metabolism. Androgen signaling also ... (Source: BMC Cancer)
Source: BMC Cancer - October 10, 2018 Category: Cancer & Oncology Authors: Kasey Jividen, Katarzyna Z Kedzierska, Chun-Song Yang, Karol Szlachta, Aakrosh Ratan and Bryce M Paschal Tags: Research article Source Type: research

Risk factors for paclitaxel-induced peripheral neuropathy in patients with breast cancer
Paclitaxel induced peripheral neuropathy (PIPN) is a major debilitating side effect of paclitaxel in patients with breast cancer with no fully known mechanisms. The aim of the study was to find out the possibl... (Source: BMC Cancer)
Source: BMC Cancer - October 5, 2018 Category: Cancer & Oncology Authors: Zohreh Ghoreishi, Seyedali Keshavarz, Mohammad Asghari Jafarabadi, Zahra Fathifar, Karyn A Goodman and Ali Esfahani Tags: Research article Source Type: research

Impact of the epidermal growth factor receptor mutation status on the prognosis of recurrent adenocarcinoma of the lung after curative surgery
The prognosis of patients with epidermal growth factor receptor (EGFR) mutant adenocarcinoma of the lung (Mt) and EGFR wild-type adenocarcinoma (Wt) after complete resection of the lung differ; however, the mecha... (Source: BMC Cancer)
Source: BMC Cancer - October 5, 2018 Category: Cancer & Oncology Authors: Tetsuya Isaka, Haruhiko Nakayama, Hiroyuki Ito, Tomoyuki Yokose, Kouzo Yamada and Munetaka Masuda Tags: Research article Source Type: research

Oral mucositis associated with anti-EGFR therapy in colorectal cancer: single institutional retrospective cohort study
Chemotherapy-induced oral mucositis impairs the quality of life. The difference in severity of oral mucositis between different anti-epidermal growth factor receptor (EGFR) antibodies combined with cytotoxic d... (Source: BMC Cancer)
Source: BMC Cancer - October 5, 2018 Category: Cancer & Oncology Authors: Satoshi Dote, Shoji Itakura, Kohei Kamei, Daiki Hira, Satoshi Noda, Yuka Kobayashi and Tomohiro Terada Tags: Research article Source Type: research

Uc.416  + A promotes epithelial-to-mesenchymal transition through miR-153 in renal cell carcinoma
The transcribed ultraconserved regions (T-UCRs) are a novel class of non-coding RNAs that are absolutely conserved across species and are involved in carcinogenesis in some cancers. However, the expression and... (Source: BMC Cancer)
Source: BMC Cancer - October 4, 2018 Category: Cancer & Oncology Authors: Yohei Sekino, Naoya Sakamoto, Keisuke Goto, Ririno Honma, Yoshinori Shigematsu, Thang Pham Quoc, Kazuhiro Sentani, Naohide Oue, Jun Teishima, Fumi Kawakami, Jose A Karam, Kanishka Sircar, Akio Matsubara and Wataru Yasui Tags: Research article Source Type: research

SoLAT (Sorafenib Lenvatinib alternating treatment): a new treatment protocol with alternating Sorafenib and Lenvatinib for refractory thyroid Cancer
In the last decade, several tyrosine kinase inhibitors (TKIs), which disrupt pathways involved in the proliferation and tumorigenesis of thyroid cancer, have been extensively studied. Two different TKIs, lenva... (Source: BMC Cancer)
Source: BMC Cancer - October 4, 2018 Category: Cancer & Oncology Authors: Soo Young Kim, Seok-Mo Kim, Ho-Jin Chang, Bup-Woo Kim, Yong Sang Lee, Cheong Soo Park, Ki Cheong Park and Hang-Seok Chang Tags: Research article Source Type: research

Population-based phase II trial of stereotactic ablative radiotherapy (SABR) for up to 5 oligometastases: SABR-5
Oligometastases refer to a state of disease where cancer has spread beyond the primary site, but is not yet widely metastatic, often defined as 1 –3 or 1–5 metastases in number. Stereotactic ablative radiothera... (Source: BMC Cancer)
Source: BMC Cancer - October 4, 2018 Category: Cancer & Oncology Authors: Robert Olson, Mitchell Liu, Alanah Bergman, Sonya Lam, Fred Hsu, Benjamin Mou, Tanya Berrang, Ante Mestrovic, Nick Chng, Derek Hyde, Quinn Matthews, Chad Lund, Daniel Glick, Howard Pai, Parminder Basran, Hannah Carolan & hellip; Tags: Study protocol Source Type: research

Dynapenia could predict chemotherapy-induced dose-limiting neurotoxicity in digestive cancer patients
FIGHTDIGO study showed the feasibility and acceptability of handgrip strength (HGS) measure in routine in 201 consecutive patients with digestive cancer treated with ambulatory chemotherapy. The present study ... (Source: BMC Cancer)
Source: BMC Cancer - October 4, 2018 Category: Cancer & Oncology Authors: Damien Botsen, Marie-Am élie Ordan, Coralie Barbe, Camille Mazza, Marine Perrier, Johanna Moreau, Mathilde Brasseur, Yohann Renard, Barbara Taillière, Florian Slimano, Eric Bertin and Olivier Bouché Tags: Research article Source Type: research

ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan
Many studies have shown that lifestyle factors such as diet, physical activity are related to the incidence of cancer. However, there are few studies on the association between lifestyle factors and cancer pro... (Source: BMC Cancer)
Source: BMC Cancer - October 4, 2018 Category: Cancer & Oncology Authors: Yuri Mizota, Yukihide Kanemitsu, Shunsuke Tsukamoto, Dai Shida, Hiroki Ochiai and Seiichiro Yamamoto Tags: Study protocol Source Type: research

Prediction of perioperative complications after robotic-assisted radical hysterectomy for cervical cancer using the modified surgical Apgar score
Although there has been marked development in surgical techniques, there is no easy and fast method of predicting complications in minimally invasive surgeries. We evaluated whether the modified surgical Apgar... (Source: BMC Cancer)
Source: BMC Cancer - September 21, 2018 Category: Cancer & Oncology Authors: Seon Hee Park, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim and Young Tae Kim Tags: Research article Source Type: research

Predictive and prognostic value of Matrix metalloproteinase (MMP) - 9 in neoadjuvant chemotherapy for triple-negative breast cancer patients
This study aimed to investigate the clinical utility of serum and histological MMP-9 detection during neoadjuvant chemotherapy (NAC) for triple-negative breast cancer (TNBC). (Source: BMC Cancer)
Source: BMC Cancer - September 21, 2018 Category: Cancer & Oncology Authors: Ruo-Xi Wang, Sheng Chen, Liang Huang and Zhi-Ming Shao Tags: Research article Source Type: research

A trend towards a more intense adjuvant treatment of low-grade-gliomas in tertiary centers in Germany after RTOG 9802 – results from a multi-center survey
The treatment recommendations for Low-grade Gliomas (LGG) underwent profound changes due to results from RTOG 9802 published in April 2016. This work aims to investigate whether the results from the trial were... (Source: BMC Cancer)
Source: BMC Cancer - September 21, 2018 Category: Cancer & Oncology Authors: Christoph Straube, Kerstin A. Kessel, Friederike Schmidt-Graf, Sandro M. Krieg, Bernhard Meyer, Jens Gempt and Stephanie E. Combs Tags: Research article Source Type: research

The supportive care needs of women experiencing gynaecological cancer: a Western Australian cross-sectional study
Women diagnosed with gynaecological cancer experience supportive care needs that require care provision to reduce the impact on their lives. International evidence suggests supportive care needs of women with ... (Source: BMC Cancer)
Source: BMC Cancer - September 21, 2018 Category: Cancer & Oncology Authors: Natalie Williams, Georgia Griffin, Victoria Farrell, Alethea Rea, Kevin Murray and Yvonne L. Hauck Tags: Research article Source Type: research

PEG-L-CHOP treatment is safe and effective in adult extranodal NK/T-cell lymphoma with a low rate of clinical hypersensitivity
The combination of chemotherapy and L-asparaginase (L-ASP) treatment significantly increased survival rate in an adult patient with extranodal natural killer (NK)/T-cell lymphoma (NKTCL). However, hypersensitivit... (Source: BMC Cancer)
Source: BMC Cancer - September 21, 2018 Category: Cancer & Oncology Authors: Wen Zheng, Yuhuan Gao, Xiaoyan Ke, Weijing Zhang, Liping Su, Hanyun Ren, Ningjing Lin, Yan Xie, Meifeng Tu, Weiping Liu, Lingyan Ping, Zhitao Ying, Chen Zhang, Lijuan Deng, Xiaopei Wang, Yuqin Song & hellip; Tags: Research article Source Type: research

Endometriosis-associated recto-sigmoid cancer: a case report
We report a case in which a patient with a history of end... (Source: BMC Cancer)
Source: BMC Cancer - September 20, 2018 Category: Cancer & Oncology Authors: Ningning Li, Weixun Zhou, Lin Zhao and Jiaolin Zhou Tags: Case report Source Type: research

A new promising way of maintenance therapy in advanced ovarian cancer: a comparative clinical study
There is an urgent need for more novel and efficacious therapeutic agents and strategies for the treatment of ovarian cancer - one of the most formidable female malignancies. These approaches should be based o... (Source: BMC Cancer)
Source: BMC Cancer - September 20, 2018 Category: Cancer & Oncology Authors: Vsevolod I. Kiselev, Levon A. Ashrafyan, Ekaterina L. Muyzhnek, Evgeniya V. Gerfanova, Irina B. Antonova, Olga I. Aleshikova and Fazlul H. Sarkar Tags: Research article Source Type: research

A review of sex-related differences in colorectal cancer incidence, screening uptake, routes to diagnosis, cancer stage and survival in the UK
Colorectal cancer (CRC) is an illness strongly influenced by sex and gender, with mortality rates in males significantly higher than females. There is still a dearth of understanding on where sex differences e... (Source: BMC Cancer)
Source: BMC Cancer - September 20, 2018 Category: Cancer & Oncology Authors: Alan White, Lucy Ironmonger, Robert J. C. Steele, Nick Ormiston-Smith, Carina Crawford and Amanda Seims Tags: Research article Source Type: research

Predicting treatment Response based on Dual assessment of magnetic resonance Imaging kinetics and Circulating Tumor cells in patients with Head and Neck cancer (PREDICT-HN): matching ‘liquid biopsy’ and quantitative tumor modeling
Magnetic resonance imaging (MRI) has improved capacity to visualize tumor and soft tissue involvement in head and neck cancers. Using advanced MRI, we can interrogate cell density using diffusion weighted imag... (Source: BMC Cancer)
Source: BMC Cancer - September 19, 2018 Category: Cancer & Oncology Authors: Sweet Ping Ng, Houda Bahig, Jihong Wang, Carlos E. Cardenas, Anthony Lucci, Carolyn S. Hall, Salyna Meas, Vanessa N. Sarli, Ying Yuan, Diana L. Urbauer, Yao Ding, Shane Ikner, Vi Dinh, Baher A. Elgohari, Jason M. Johnson, Heath D. Skinner & hellip; Tags: Study protocol Source Type: research

Extracellular matrix collagen I promotes the tumor progression of residual hepatocellular carcinoma after heat treatment
Accelerated malignant behaviors induced by insufficient thermal ablation have been increasingly reported, however, the exact mechanisms are still unclear. Here, we investigated the importance of the extracellu... (Source: BMC Cancer)
Source: BMC Cancer - September 18, 2018 Category: Cancer & Oncology Authors: Rui Zhang, Min Ma, Xia-Hui Lin, Hua-Hua Liu, Jie Chen, Jun Chen, Dong-Mei Gao, Jie-Feng Cui, Zheng-Gang Ren and Rong-Xin Chen Tags: Research article Source Type: research

Detection of PIK3/AKT pathway in Moroccan population with triple negative breast cancer
Triple Negative Breast Cancer (TNBC) is an aggressive form of breast cancer, that represents 10 –20% of all breast carcinomas and characterized by the lack of a specific cell surface marker compared to other br... (Source: BMC Cancer)
Source: BMC Cancer - September 18, 2018 Category: Cancer & Oncology Authors: Farah Jouali, Nabila Marchoudi, Salwa Talbi, Basma Bilal, Mohamed El Khasmi, Houria Rhaissi and Jamal Fekkak Tags: Research article Source Type: research

Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer
Interactions between cancer cells and the surrounding microenvironment are crucial determinants of cancer progression. During this process, bi-directional communication among tumor cells and cancer associated ... (Source: BMC Cancer)
Source: BMC Cancer - September 18, 2018 Category: Cancer & Oncology Authors: Francesca Andriani, Elena Landoni, Mavis Mensah, Federica Facchinetti, Rosalba Miceli, Elda Tagliabue, Marta Giussani, Maurizio Callari, Loris De Cecco, Mario Paolo Colombo, Luca Roz, Ugo Pastorino and Gabriella Sozzi Tags: Research article Source Type: research

Correction to: Daphnane diterpenes inhibit the metastatic potential of B16F10 murine melanoma cells in vitro and in vivo
ᅟ (Source: BMC Cancer)
Source: BMC Cancer - September 18, 2018 Category: Cancer & Oncology Authors: Myra O. Villareal, Yuki Sato, Kyoko Matsuyama and Hiroko Isoda Tags: Correction Source Type: research

MiR-126 in intestinal-type sinonasal adenocarcinomas: exosomal transfer of MiR-126 promotes anti-tumour responses
Intestinal-type sinonasal adenocarcinomas (ITACs) are aggressive malignancies related to wood dust and leather exposure. ITACs are generally associated with advanced stage at presentation due to the insidious ... (Source: BMC Cancer)
Source: BMC Cancer - September 17, 2018 Category: Cancer & Oncology Authors: Marco Tomasetti, Massimo Re, Federica Monaco, Simona Gaetani, Corrado Rubini, Andrea Bertini, Ernesto Pasquini, Cristiana Bersaglieri, Massimo Bracci, Sara Staffolani, Mariastella Colomba, Armando Gregorini, Matteo Valentino, Adriano Tagliabracci, Massimo Tags: Research article Source Type: research

Development and validation of a new predictive model for breast cancer survival in New Zealand and comparison to the Nottingham prognostic index
The only available predictive models for the outcome of breast cancer patients in New Zealand (NZ) are based on data in other countries. We aimed to develop and validate a predictive model using NZ data for th... (Source: BMC Cancer)
Source: BMC Cancer - September 17, 2018 Category: Cancer & Oncology Authors: J. Mark Elwood, Essa Tawfiq, Sandar TinTin, Roger J. Marshall, Tung M. Phung, Ian Campbell, Vernon Harvey and Ross Lawrenson Tags: Research article Source Type: research

EXclusion of non-Involved uterus from the Target Volume (EXIT-trial): an individualized treatment for locally advanced cervical cancer using modern radiotherapy and imaging techniques
Definitive chemoradiotherapy is standard of care in locally advanced cervical cancer (LACC). Both toxicity and local relapse remain major concerns in this treatment. We hypothesize that a magnetic resonance im... (Source: BMC Cancer)
Source: BMC Cancer - September 17, 2018 Category: Cancer & Oncology Authors: Katrien Vandecasteele, Philippe Tummers, Mieke Van Bockstal, Pieter De Visschere, Tom Vercauteren, Werner De Gersem, Hannelore Denys, Eline Naert, Amin Makar and Wilfried De Neve Tags: Study protocol Source Type: research

TUSC2P suppresses the tumor function of esophageal squamous cell carcinoma by regulating TUSC2 expression and correlates with disease prognosis
Pseudogenes are RNA transcripts with high homology with its parent protein-coding genes. Although pseudogenes lost the ability to produce protein, it still exert import biological function, and play important ... (Source: BMC Cancer)
Source: BMC Cancer - September 15, 2018 Category: Cancer & Oncology Authors: Fengqiong Liu, Ruijie Gong, Baochang He, Fa Chen and Zhijian Hu Tags: Research article Source Type: research

Early cost-effectiveness of tumor infiltrating lymphocytes (TIL) for second line treatment in advanced melanoma: a model-based economic evaluation
An emerging immunotherapy is infusion of tumor infiltrating Lymphocytes (TIL), with objective response rates of around 50% versus 19% for ipilimumab. As an Advanced Therapeutic Medicinal Products (ATMP), TIL i... (Source: BMC Cancer)
Source: BMC Cancer - September 15, 2018 Category: Cancer & Oncology Authors: Valesca P. Ret èl, Lotte M. G. Steuten, Marnix H. Geukes Foppen, Janne C. Mewes, Melanie A. Lindenberg, John B. A. G. Haanen and Wim H. van Harten Tags: Research article Source Type: research

Polymorphisms in the H19 gene and the risk of lung Cancer among female never smokers in Shenyang, China
This study assessed the association between H19 genetic polymorphisms and the susceptibility of lung cancer. (Source: BMC Cancer)
Source: BMC Cancer - September 15, 2018 Category: Cancer & Oncology Authors: Zhihua Yin, Zhigang Cui, Hang Li, Juan Li and Baosen Zhou Tags: Research article Source Type: research

Validation of a frailty index in older cancer patients with solid tumours
Frailty is an indicator of physiological reserve in older people. In non-cancer settings, frailty indices are reliable predictors of adverse health outcomes. The aims of this study were to 1) derive and valida... (Source: BMC Cancer)
Source: BMC Cancer - September 14, 2018 Category: Cancer & Oncology Authors: A. L. McCarthy, N. M. Peel, K. M. Gillespie, R. Berry, E. Walpole, P. Yates and R. E. Hubbard Tags: Research article Source Type: research

EGFR mutation frequency in Middle East and African non-small cell lung cancer patients: a systematic review and meta-analysis
Our goal was to investigate the prevalence of the epidermal growth factor receptor (EGFR) mutation in Middle East and African countries and to compare its prevalence with that shown in other populations. (Source: BMC Cancer)
Source: BMC Cancer - September 14, 2018 Category: Cancer & Oncology Authors: Zineb Benbrahim, Teresita Antonia and Nawfel Mellas Tags: Research article Source Type: research

Genomic profiles of primary and metastatic esophageal adenocarcinoma identified via digital sorting of pure cell populations: results from a case report
We report on a female patient who underwent primary radical resection for a stage 2B Her-2-positive Barrett ’s-type esophageal adenocarcinoma (EAC). Despite Her-2 targeted therapy, her disease recurred and requ... (Source: BMC Cancer)
Source: BMC Cancer - September 12, 2018 Category: Cancer & Oncology Authors: Federica Isidori, Deborah Malvi, Silvia Fittipaldi, Claudio Forcato, Isotta Bozzarelli, Claudia Sala, Giovanni Raulli, Antonia D ’Errico, Michelangelo Fiorentino, Marco Seri, Kausilia K. Krishnadath, Elena Bonora and Sandro Mattioli Tags: Case report Source Type: research

Study protocol: HepaT1ca – an observational clinical cohort study to quantify liver health in surgical candidates for liver malignancies
Accurate assessment of liver health prior to undertaking resectional liver surgery or chemoembolisation for primary and secondary cancers is essential for patient safety and optimal outcomes. LiverMultiScan ™, an ... (Source: BMC Cancer)
Source: BMC Cancer - September 12, 2018 Category: Cancer & Oncology Authors: Damian J. Mole, Jonathan A. Fallowfield, Timothy J. Kendall, Fenella Welsh, Scott I. Semple, Velicia Bachtiar, Matt Kelly, Stephen J. Wigmore, O. James Garden, Henry R. Wilman, Rajarshi Banerjee, Myrddin Rees and Michael Brady Tags: Study protocol Source Type: research

Clinical benefit and radiological response with BRAF inhibitor in a patient with recurrent ameloblastoma harboring V600E mutation
Ameloblastoma is a slow-growing neoplasm of the jaw, for which the standard treatment is surgical removal of the lesion with high recurrence rates and elevated morbidity. Systemic therapy is not established in... (Source: BMC Cancer)
Source: BMC Cancer - September 12, 2018 Category: Cancer & Oncology Authors: Gustavo S. Fernandes, Daniel M. Girardi, Jo ão Paulo G. Bernardes, Felipe P. Fonseca and Eduardo R. Fregnani Tags: Case report Source Type: research

‘DURVIT’: a phase-I trial of single low-dose durvalumab (Medi4736) IntraTumourally injected in cervical cancer: safety, toxicity and effect on the primary tumour- and lymph node microenvironment
Treatment with programmed cell death receptor (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors is a promising strategy to lift tumour-induced immune response suppression. However, the current syste... (Source: BMC Cancer)
Source: BMC Cancer - September 12, 2018 Category: Cancer & Oncology Authors: J. Rotman, C. H. Mom, E. S. Jordanova, T. D. de Gruijl and G. G. Kenter Tags: Study protocol Source Type: research

Effects of whole-body electromyostimulation combined with individualized nutritional support on body composition in patients with advanced cancer: a controlled pilot trial
Physical exercise and nutritional treatment are promising measures to prevent muscle wasting that is frequently observed in advanced-stage cancer patients. However, conventional exercise is not always suitable... (Source: BMC Cancer)
Source: BMC Cancer - September 12, 2018 Category: Cancer & Oncology Authors: Kristin Schink, Hans J. Herrmann, Raphaela Schwappacher, Julia Meyer, Till Orlemann, Elisabeth Waldmann, Bernd Wullich, Andreas Kahlmeyer, Rainer Fietkau, Dorota Lubgan, Matthias W. Beckmann, Carolin Hack, Wolfgang Kemmler, J ürgen Siebler, Markus F. Neu Tags: Research article Source Type: research

Could local surgery improve survival in de novo stage IV breast cancer?
Resection of the primary tumor is recommended for symptom relief in de novo stage IV breast cancer. We explored whether local surgery could provide a survival benefit in these patients and attempted to charact... (Source: BMC Cancer)
Source: BMC Cancer - September 11, 2018 Category: Cancer & Oncology Authors: Zhenchong Xiong, Guangzheng Deng, Jin Wang, Xing Li, Xinhua Xie, Zeyu Shuang and Xi Wang Tags: Research article Source Type: research

Correction to: Observational study on the prognostic value of testosterone and adiposity in postmenopausal estrogen receptor positive breast cancer patients
Following publication of the original article [1], the authors reported that the affiliation of author Annalisa Orenti was omitted. (Source: BMC Cancer)
Source: BMC Cancer - September 10, 2018 Category: Cancer & Oncology Authors: Elisabetta Venturelli, Annalisa Orenti, Aline S. C. Fabricio, Giulia Garrone, Roberto Agresti, Biagio Paolini, Chiara Bonini, Massimo Gion, Franco Berrino, Christine Desmedt, Danila Coradini and Elia Biganzoli Tags: Correction Source Type: research

Nomograms for predicting risk of locoregional recurrence and distant metastases for esophageal cancer patients after radical esophagectomy
The aim of this study was to develop nomograms for predicting the risk of locoregional recurrence or distant metastasis in esophageal cancer patients who were treated with esophagectomy and regional lymphadene... (Source: BMC Cancer)
Source: BMC Cancer - September 10, 2018 Category: Cancer & Oncology Authors: Wen-Yi Zhang, Xing-Xing Chen, Wen-Hao Chen, Hui Zhang and Chang-Lin Zou Tags: Research article Source Type: research