Cardiovascular disease in women with breast cancer – a nationwide cohort study
There is increasing concern about cardiovascular disease (CVD) after breast cancer (BC). The aim of this study was to estimate the prevalence of different types of CVD in women diagnosed with BC compared to ca... (Source: BMC Cancer)
Source: BMC Cancer - September 18, 2021 Category: Cancer & Oncology Authors: Marie Jakobsen, Christophe Kolodziejczyk, Morten Sall Jensen, Peter Bo Poulsen, Humma Khan, Thomas K ümler and Michael Andersson Tags: Research article Source Type: research

Prevention of radiotherapy induced enteropathy by probiotics (PREP): protocol for a double-blind randomized placebo-controlled trial
Radiation induced enteropathy is a common complication of radiotherapy for pelvic tumors and adversely affects patient quality of life. Probiotics are thought to restore bowel microflora to optimal levels and ... (Source: BMC Cancer)
Source: BMC Cancer - September 16, 2021 Category: Cancer & Oncology Authors: Yeon Joo Kim, Jesang Yu, Sung Pyo Park, Seung Hae Lee and Young Seok Kim Tags: Study protocol Source Type: research

Pyrotinib combined with thalidomide in advanced non-small-cell lung cancer patients harboring HER2 exon 20 insertions (PRIDE): protocol of an open-label, single-arm phase II trial
Standard therapy for human epidermal growth factor receptor 2 (HER2)-mutant non-small-cell lung cancer (NSCLC) is lacking. The clinical benefits with pan-HER inhibitors (afatinib, neratinib, and dacomitinib), ... (Source: BMC Cancer)
Source: BMC Cancer - September 16, 2021 Category: Cancer & Oncology Authors: Xinghao Ai, Zhengbo Song, Hong Jian, Zhen Zhou, Zhiwei Chen, Yongfeng Yu, Ziming Li and Shun Lu Tags: Study protocol Source Type: research

Biomarker-based early detection of epithelial ovarian cancer based on a five-protein signature in patient ’s plasma – a prospective trial
Trial on five plasma biomarkers (CA125, HE4, OPN, leptin, prolactin) and their possible role in differentiating benign from malignant ovarian tumors. (Source: BMC Cancer)
Source: BMC Cancer - September 16, 2021 Category: Cancer & Oncology Authors: A. Hasenburg, D. Eichkorn, F. Vosshagen, E. Obermayr, A. Geroldinger, R. Zeillinger and M. Bossart Tags: Research article Source Type: research

Prediction of serosal invasion in gastric cancer: development and validation of multivariate models integrating preoperative clinicopathological features and radiographic findings based on late arterial phase CT images
To develop and validate multivariate models integrating endoscopic biopsy, tumor markers, and CT findings based on late arterial phase (LAP) to predict serosal invasion in gastric cancer (GC). (Source: BMC Cancer)
Source: BMC Cancer - September 16, 2021 Category: Cancer & Oncology Authors: Song Liu, Mengying Xu, Xiangmei Qiao, Changfeng Ji, Lin Li and Zhengyang Zhou Tags: Research Source Type: research

A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine and platinum-based chemotherapy in gastric cancer
Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric cancer (GC). Guidelines exist for the clinical interpretation of four DPYD genotypes related to severe fluoropy... (Source: BMC Cancer)
Source: BMC Cancer - September 16, 2021 Category: Cancer & Oncology Authors: Miguel Cordova-Delgado, Mar ía Loreto Bravo, Elisa Cumsille, Charlotte N. Hill, Matías Muñoz-Medel, Mauricio P. Pinto, Ignacio N. Retamal, María A. Lavanderos, Juan Francisco Miquel, Maria Rodriguez-Fernandez, Yuwei Liao, Zhiguang Li, Alejandro H. Cor Tags: Research Source Type: research

Cervical cancer screening “see and treat approach”: real-life uptake after invitation and associated factors at health facilities in Gondar, Northwest Ethiopia
Although cervical cancer is a preventable disease, screening coverage in Ethiopia is far below the target. There is limited evidence on uptake among the general population in Ethiopia. Thus, this study was con... (Source: BMC Cancer)
Source: BMC Cancer - September 16, 2021 Category: Cancer & Oncology Authors: Alemnew Destaw, Miresa Midaksa, Adamu Addissie, Eva Johanna Kantelhardt and Muluken Gizaw Tags: Research Source Type: research

eIF5B regulates the expression of PD-L1 in prostate cancer cells by interacting with Wig1
Eukaryotic translation initiation factors (eIFs) are the key factors to synthesize translation initiation complexes during the synthesis of eukaryotic proteins. Besides, eIFs are especially important in regula... (Source: BMC Cancer)
Source: BMC Cancer - September 15, 2021 Category: Cancer & Oncology Authors: Qi Li, Mulun Xiao, Yibo Shi, Jinhao Hu, Tianxiang Bi, Chaoliang Wang, Liang Yan and Xiaoyan Li Tags: Research Source Type: research

Correction to: Outcomes based on plasma biomarkers in METEOR, a randomized phase 3 trial of cabozantinib vs everolimus in advanced renal cell carcinoma
(Source: BMC Cancer)
Source: BMC Cancer - September 15, 2021 Category: Cancer & Oncology Authors: Thomas Powles, Toni K. Choueiri, Robert J. Motzer, Eric Jonasch, Sumanta Pal, Nizar M. Tannir, Sabina Signoretti, Rajesh Kaldate, Christian Scheffold, Evelyn Wang, Dana T. Aftab, Bernard Escudier and Daniel J. George Tags: Correction Source Type: research

Correction to: TGFB-induced factor homeobox 1 (TGIF) expression in breast cancer
(Source: BMC Cancer)
Source: BMC Cancer - September 15, 2021 Category: Cancer & Oncology Authors: Christine St ürken, Volker Möbus, Karin Milde-Langosch, Sabine Schmatloch, Peter A. Fasching, Josef Rüschoff, Elmar Stickeler, Rolf-Peter Henke, Carsten Denkert, Lars Hanker, Christian Schem, Valentina Vladimirova, Thomas Karn, Valentina Nekljudova, Cl Tags: Correction Source Type: research

Infrequent RAS mutation is not associated with specific histological phenotype in gliomas
Mutations in driver genes such as IDH and BRAF have been identified in gliomas. Meanwhile, dysregulations in the p53, RB1, and MAPK and/or PI3K pathways are involved in the molecular pathogenesis of glioblastoma.... (Source: BMC Cancer)
Source: BMC Cancer - September 15, 2021 Category: Cancer & Oncology Authors: Yasuhide Makino, Yoshiki Arakawa, Ema Yoshioka, Tomoko Shofuda, Sachiko Minamiguchi, Takeshi Kawauchi, Masahiro Tanji, Daisuke Kanematsu, Masahiro Nonaka, Yoshiko Okita, Yoshinori Kodama, Masayuki Mano, Takanori Hirose, Yohei Mineharu, Susumu Miyamoto and Tags: Research Source Type: research

Co-expression and prognosis analyses of GLUT1 –4 and RB1 in breast cancer
Current treatment methods for patients with triple-negative breast cancer (TNBC) are very limited, and the prognosis of TNBC is relatively poor. It has been reported that glucose transporter 1 (GLUT1) is overe... (Source: BMC Cancer)
Source: BMC Cancer - September 15, 2021 Category: Cancer & Oncology Authors: Xiaodan Zhang, Xiaocong Pang, Zhuo Zhang, Qianxin Liu, Hanxu Zhang, Qian Xiang and Yimin Cui Tags: Research Source Type: research

Prevalence and associations of axillary web syndrome in Asian women after breast cancer surgery undergoing a community-based cancer rehabilitation program
Patients who have breast cancer surgery are at risk of axillary web syndrome (AWS), an under-recognized postsurgical complication which can result in shoulder morbidity and functional impairment. Emerging stud... (Source: BMC Cancer)
Source: BMC Cancer - September 14, 2021 Category: Cancer & Oncology Authors: Matthew Rong Jie Tay, Chin Jung Wong and Hui Zhen Aw Tags: Research Source Type: research

Brachytherapy with Iodine-125 seeds for treatment of portal vein-branch tumor thrombus in patients with hepatocellular carcinoma
There is currently no widely-accepted consensus for the management of hepatocellular carcinoma with portal vein tumor thrombus. We evaluate the safety and efficacy of ultrasound-guided percutaneous brachythera... (Source: BMC Cancer)
Source: BMC Cancer - September 14, 2021 Category: Cancer & Oncology Authors: Duo Hong, Yi Zhou, Xiaoting Wan, Hongying Su and Haibo Shao Tags: Research article Source Type: research

Prospective observational study on Pazopanib in patients treated for advanced or metastatic renal cell carcinoma in countries in Asia Pacific, North Africa, and Middle East regions: PARACHUTE study
Clinical effectiveness and safety data of pazopanib in patients with advanced or mRCC in real-world setting from Asia Pacific, North Africa, and Middle East countries are lacking. (Source: BMC Cancer)
Source: BMC Cancer - September 14, 2021 Category: Cancer & Oncology Authors: Erman Mustafa, Biswas Bivas, Danchaivijitr Pongwut, Chen Lingwu, Yoke Fui Wong, Tarek Hashem, Chun Sen Lim, Bulent Karabulut, Hsiao-Jen Chung, Chandra Chikatapu, Sara Ingles, Khemaies Slimane and Ravindran Kanesvaran Tags: Research Source Type: research

Influence of migrant background on patient preference and expectations in breast and gynecological malignancies (NOGGO-expression V study): results of a prospective multicentre study in 606 patients in Germany
An effective cross-cultural doctor-patient communication is vital for health literacy and patient compliance. Building a good relationship with medical staff is also relevant for the treatment decision-making ... (Source: BMC Cancer)
Source: BMC Cancer - September 12, 2021 Category: Cancer & Oncology Authors: D. Dimitrova, B. Naghavi, R. Richter, S. Nasser, R. Chekerov, E. I. Braicu, M. David, J. Blohmer, G. Inci, U. Torsten, G. Oskay- Özcelik, I. Blau, N. Fersis, A. Holzgreve, E. Keil, M. Keller & hellip; Tags: Research Source Type: research

Postoperative morbidity and quality of life between totally laparoscopic total gastrectomy and laparoscopy-assisted total gastrectomy: a propensity-score matched analysis
This study aimed to evaluate the surgical outcome and quality of life (QoL) of totally laparoscopic total gastrectomy (TLTG) compared with laparoscopy-assisted total gastrectomy (LATG) in patients with clinica... (Source: BMC Cancer)
Source: BMC Cancer - September 11, 2021 Category: Cancer & Oncology Authors: Shin-Hoo Park, Yun-Suhk Suh, Tae-Han Kim, Yoon-Hee Choi, Jong-Ho Choi, Seong-Ho Kong, Do Joong Park, Hyuk-Joon Lee and Han-Kwang Yang Tags: Research Source Type: research

Estrogen markedly reduces circulating low-density neutrophils and enhances pro-tumoral gene expression in neutrophil of tumour-bearing mice
Neutrophils are important for immune surveillance of tumour cells. Neutrophils may also be epigenetically programmed in the tumour microenvironment to promote tumour progression. In addition to the commonly kn... (Source: BMC Cancer)
Source: BMC Cancer - September 11, 2021 Category: Cancer & Oncology Authors: Chew Leng Lim and Valerie C.-L. Lin Tags: Research Source Type: research

The role of Magnetic Resonance Images (MRIs) in coping for patients with brain tumours and their parents: a qualitative study
When children and young people (CYP) are diagnosed with a brain tumour, Magnetic Resonance Imaging (MRI) is key to the clinical management of this condition. This can produce hundreds, and often thousands, of ... (Source: BMC Cancer)
Source: BMC Cancer - September 10, 2021 Category: Cancer & Oncology Authors: Natalie Tyldesley-Marshall, Sheila Greenfield, Susan J. Neilson, Martin English, Jenny Adamski and Andrew Peet Tags: Research Source Type: research

Adjuvant immunotherapy recommendations for stage III melanoma: physician and nurse interviews
This study a... (Source: BMC Cancer)
Source: BMC Cancer - September 10, 2021 Category: Cancer & Oncology Authors: Ann Livingstone, Kathy Dempsey, Martin R. Stockler, Kirsten Howard, Georgina V. Long, Matteo S. Carlino, Alexander M. Menzies and Rachael L. Morton Tags: Research Source Type: research

18F-FDG-PET-MRI for the assessment of acute intestinal graft-versus-host-disease (GvHD)
Graft versus host disease (GvHD) is a frequent complication of allogeneic stem cell transplantation (alloSCT), significantly increasing mortality. Previous imaging studies focused on the assessment of intestin... (Source: BMC Cancer)
Source: BMC Cancer - September 10, 2021 Category: Cancer & Oncology Authors: Wolfgang Roll, Philipp Schindler, Max Masthoff, Rebecca Strotmann, J örn Albring, Christian Reicherts, Matthias Weckesser, Benjamin Noto, Matthias Stelljes, Michael Schäfers and Georg Evers Tags: Research Source Type: research

Application of CD54 in diagnosing bone marrow involvement by using flow cytometry in patients with diffuse large B-cell lymphoma
Flow cytometry plays a key role in detecting bone marrow (BM) involvement in patients with diffuse large B-cell lymphoma (DLBCL). To improve its detection sensitivity, we need to explore novel markers. In this... (Source: BMC Cancer)
Source: BMC Cancer - September 9, 2021 Category: Cancer & Oncology Authors: Wei Wang, Yan Li, Xavier Rivera Rivera, Linjun Zhao, Di Mei, Wenqing Hu and Bin Jiang Tags: Research Source Type: research

Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway
UEV1A encodes a ubiquitin-E2 variant closely associated with tumorigenesis and metastasis, but its underlying mechanism in promoting metastasis remains to be investigated. (Source: BMC Cancer)
Source: BMC Cancer - September 9, 2021 Category: Cancer & Oncology Authors: Tong Niu, Zhaojia Wu and Wei Xiao Tags: Research Source Type: research

Study protocol for OptimalTTF-2: enhancing Tumor Treating Fields with skull remodeling surgery for first recurrence glioblastoma: a phase 2, multi-center, randomized, prospective, interventional trial
OptimalTTF-2 is a randomized, comparative, multi-center, investigator-initiated, interventional study aiming to test skull remodeling surgery in combination with Tumor Treating Fields therapy (TTFields) and be... (Source: BMC Cancer)
Source: BMC Cancer - September 9, 2021 Category: Cancer & Oncology Authors: N. Mikic, F. R. Poulsen, K. B. Kristoffersen, R. J. Laursen, T. L. Guldberg, J. Skj øth-Rasmussen, E. T. Wong, S. Møller, R. H. Dahlrot, J. C. H. Sørensen and A. R. Korshøj Tags: Study protocol Source Type: research

Evaluating the effect of Neoadjuvant chemotherapy for esophageal Cancer using the RECIST system with shorter-axis measurements: a retrospective multicenter study
Evaluating the effect on primary lesions is important in determining treatment strategies for esophageal cancer. The Response Evaluation Criteria in Solid Tumors system, which employs the longest diameter for ... (Source: BMC Cancer)
Source: BMC Cancer - September 9, 2021 Category: Cancer & Oncology Authors: Yusuke Taniyama, Kentaro Murakami, Naoya Yoshida, Kozue Takahashi, Hisahiro Matsubara, Hideo Baba and Takashi Kamei Tags: Research Source Type: research

Incidence and survival analyses for occult lung cancer between 2004 and 2015: a population-based study
This study aimed to investigate the incidence and long-term survival outcomes of occult lung cancer between 2004 and 2015. (Source: BMC Cancer)
Source: BMC Cancer - September 9, 2021 Category: Cancer & Oncology Authors: Lei-Lei Wu, Chong-Wu Li, Wei-Kang Lin, Li-Hong Qiu and Dong Xie Tags: Research Source Type: research

Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in head and neck. Platinum-based chemotherapy is an important treatment for NPC. However, the molecular mechanism of resistance to platinum... (Source: BMC Cancer)
Source: BMC Cancer - September 8, 2021 Category: Cancer & Oncology Authors: Tian Xia, Hui Tian, Kaiwen Zhang, Siyu Zhang, Wenhui Chen, Si Shi and Yiwen You Tags: Research article Source Type: research

Weight changes according to treatment in a diverse cohort of breast cancer patients
Weight changes are common among breast cancer patients. The majority of studies to date have focused on weight gain after a breast cancer diagnosis and its implications on health in survivors. Fewer studies ha... (Source: BMC Cancer)
Source: BMC Cancer - September 8, 2021 Category: Cancer & Oncology Authors: Jami Fukui, Kami White, Timothy B. Frankland, Caryn Oshiro and Lynne Wilkens Tags: Research article Source Type: research

Dysregulated paired related homeobox 1 impacts on hepatocellular carcinoma phenotypes
Hepatocellular carcinoma (HCC) is a major cause of cancer-related death. Paired related homeobox 1 (PRRX1) is a transcription factor that regulates cell growth and differentiation, but its importance in HCC is... (Source: BMC Cancer)
Source: BMC Cancer - September 8, 2021 Category: Cancer & Oncology Authors: Weronika Pioro ńska, Zeribe Chike Nwosu, Mei Han, Michael Büttner, Matthias Philip Ebert, Steven Dooley and Christoph Meyer Tags: Research Source Type: research

Analysis of the correlation between high iodized salt intake and the risk of thyroid nodules: a large retrospective study
Currently, whether daily excess iodized salt intake increases the risk of thyroid nodules and even thyroid cancer remains controversial. Our research group aimed to provide a theoretical basis for the clinical... (Source: BMC Cancer)
Source: BMC Cancer - September 7, 2021 Category: Cancer & Oncology Authors: Yaohui Wang, Jiangang Wang, Zhihen Chen, Min Ma, Changwei Lin, Qingnan He and Mingzhu Ye Tags: Research Source Type: research

Transcriptional analysis of the expression, prognostic value and immune infiltration activities of the COMMD protein family in hepatocellular carcinoma
The copper metabolism MURR1 domain (COMMD) protein family involved in tumor development and progression in several types of human cancer, but little is known about the function of COMMD proteins in hepatocellu... (Source: BMC Cancer)
Source: BMC Cancer - September 7, 2021 Category: Cancer & Oncology Authors: Xiaobo Wang, Shujiao He, Xin Zheng, Shanzhou Huang, Honghui Chen, Huadi Chen, Weixin Luo, Zhiyong Guo, Xiaoshun He and Qiang Zhao Tags: Research article Source Type: research

CML derived exosomes promote tumor favorable functional performance in T cells
Leukemic cells facilitate the creation of the tumor-favorable microenvironment in the bone marrow niche using their secreted factors. There are not comprehensive details about immunosuppressive properties of c... (Source: BMC Cancer)
Source: BMC Cancer - September 7, 2021 Category: Cancer & Oncology Authors: Nazli Jafarzadeh, Mohammad Ali Gholampour, Mohammad-Reza Alivand, Saeideh Kavousi, Laleh Arzi, Fariba Rad, Majid Sadeghizadeh and Majid Pornour Tags: Research Source Type: research

Association study of relationships of polymorphisms in the miR-21, miR-26b, miR-221/222 and miR-126 genes with cervical intraepithelial neoplasia and cervical cancer
miR-21, miR-26b, miR-221/222 and miR-126 play crucial roles in cervical cancer development. Studies have shown that polymorphisms in miRNA genes can affect miRNA expression, which might be associated with cancer ... (Source: BMC Cancer)
Source: BMC Cancer - September 7, 2021 Category: Cancer & Oncology Authors: Jia Yang, Zhiling Yan, Yingying Wang, Jinmei Xu, Rui Li, Chuanyin Li, Shuyuan Liu, Li Shi and Yufeng Yao Tags: Research Source Type: research

Race disparities in mortality by breast cancer from 2000 to 2017 in S ão Paulo, Brazil: a population-based retrospective study
This study aimed to evaluate the influence of race on breast cancer mortality in the state of S ão Paulo, from 2000 to 2017, contextualizing wit... (Source: BMC Cancer)
Source: BMC Cancer - September 7, 2021 Category: Cancer & Oncology Authors: Ana Cl áudia Marcelino, Bruno Gozzi, Cássio Cardoso-Filho, Helymar Machado, Luiz Carlos Zeferino and Diama Bhadra Vale Tags: Research Source Type: research

Up-regulation expression and prognostic significance of Syntaxin4 in kidney renal clear cell carcinoma
Syntaxin4 (STX4) gene encodes the protein STX4, a member of soluble N-ethylmaleimide-sensitive factor attachment protein receptors protein, playing a vital role in cell invadopodium formation and invasion, whi... (Source: BMC Cancer)
Source: BMC Cancer - September 6, 2021 Category: Cancer & Oncology Authors: Lishan He, Huiming Jiang, Zhenqiang Lai, Zhixiong Zhong and Zhanqin Huang Tags: Research Source Type: research

Validation of grading of non-invasive urothelial carcinoma by digital pathology for routine diagnosis
This study evaluates the reproducibility of grading these tumours on glass slides and digital pathology. (Source: BMC Cancer)
Source: BMC Cancer - September 6, 2021 Category: Cancer & Oncology Authors: Richard Colling, Hayleigh Colling, Lisa Browning and Clare Verrill Tags: Research article Source Type: research

Overexpression of UBE2C in esophageal squamous cell carcinoma tissues and molecular analysis
Esophageal cancer is a common malignant tumor and its 5-year survival rate is much lower than 30% due to its invasiveness and pronounced metastasis ability, as well as the difficulty in early diagnosis. This s... (Source: BMC Cancer)
Source: BMC Cancer - September 6, 2021 Category: Cancer & Oncology Authors: Rong Li, Xing-Feng Pang, Zhi-Guang Huang, Li-Hua Yang, Zhi-Gang Peng, Jie Ma and Rong-Quan He Tags: Research Source Type: research

Forecasting lung cancer incidence, mortality, and prevalence to year 2030
Lung cancer incidence and prevalence is increasing worldwide and there is a focus on prevention, early detection, and development of new treatments which will impact the epidemiological patterns of lung cancer... (Source: BMC Cancer)
Source: BMC Cancer - September 3, 2021 Category: Cancer & Oncology Authors: Erik Jakobsen, Karen Ege Olsen, Mette Bliddal, Malene Hornbak, Gitte F. Persson and Anders Green Tags: Research Source Type: research

A novel tool for predicting the survival of endoprosthesis used for reconstruction of the knee following tumor resection: a retrospective cohort study
Prosthesis-related complications, after knee reconstruction with endoprosthesis during operation for tumors around the knee, remain an unresolved problem which necessitate a revision or even an amputational su... (Source: BMC Cancer)
Source: BMC Cancer - September 3, 2021 Category: Cancer & Oncology Authors: Cheng-gang Pang, Xiong-gang Yang, Yun-long Zhao, Yan-cheng Liu and Yong-cheng Hu Tags: Research article Source Type: research

Clinical characteristics and risk factors associated with Pneumocystis jirovecii infection in patients with solid tumors: study of thirteen-year medical records of a large cancer center
Pneumocystis jirovecii pneumonia (PCP)-related risk factors among patients with solid tumors are not completely defined. Thus, we aimed to characterize PCP cases with underlying solid tumors, to highlight the fac... (Source: BMC Cancer)
Source: BMC Cancer - September 3, 2021 Category: Cancer & Oncology Authors: Koichi Takeda, Sohei Harada, Brian Hayama, Kosuke Hoashi, Taisuke Enokida, Toshiharu Sasaki, Koh Okamoto, Kenji Nakano and Daisuke Ohkushi Tags: Research article Source Type: research

Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors
Gastrointestinal tumors are a leading cause of mortality worldwide. As shown in our previous study, miR-1290 is overexpressed in colorectal cancer (CRC) and promotes tumor progression. We therefore aimed to ex... (Source: BMC Cancer)
Source: BMC Cancer - September 3, 2021 Category: Cancer & Oncology Authors: Liyi Xu, Yangke Cai, Xiao Chen, Yongliang Zhu and Jianting Cai Tags: Research article Source Type: research

Head and neck squamous cell carcinoma cell lines have an immunomodulatory effect on macrophages independent of hypoxia and toll-like receptor 9
A low tissue oxygen level, (Source: BMC Cancer)
Source: BMC Cancer - September 3, 2021 Category: Cancer & Oncology Authors: Tamiko Ishizu, Dominik Eichin, Artur Padzik, Sanni Tuominen, Reidar Gr énman, Marko Salmi, Tove J. Grönroos and Johanna M. Tuomela Tags: Research Source Type: research

Diagnostic utility of metabolic parameters on FDG PET/CT for lymph node metastasis in patients with cN2 non-small cell lung cancer
The aim of this study was to assess the diagnostic utility of metabolic parameters on fluorine-18-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/computed tomography (CT) for predicting lymph n... (Source: BMC Cancer)
Source: BMC Cancer - September 2, 2021 Category: Cancer & Oncology Authors: Keita Nakanishi, Shota Nakamura, Tomoshi Sugiyama, Yuka Kadomatsu, Harushi Ueno, Masaki Goto, Naoki Ozeki, Takayuki Fukui, Shingo Iwano and Toyofumi Fengshi Chen-Yoshikawa Tags: Research Source Type: research

How are we evaluating the cost-effectiveness of companion biomarkers for targeted cancer therapies? A systematic review
Despite the increasing economic assessment of biomarker-guided therapies, no clear agreement exists whether existing methods are sufficient or whether different methods might produce different cost-effectivene... (Source: BMC Cancer)
Source: BMC Cancer - September 1, 2021 Category: Cancer & Oncology Authors: Mikyung Kelly Seo and John Cairns Tags: Research Source Type: research

Exposure to low intensity ultrasound removes paclitaxel cytotoxicity in breast and ovarian cancer cells
Paclitaxel (Taxol) is a microtubule-stabilizing drug used to treat several solid tumors, including ovarian, breast, non-small cell lung, and pancreatic cancers. The current treatment of ovarian cancer is chemo... (Source: BMC Cancer)
Source: BMC Cancer - September 1, 2021 Category: Cancer & Oncology Authors: Celina Amaya, Shihua Luo, Julio Baigorri, Rogelio Baucells, Elizabeth R. Smith and Xiang-Xi Xu Tags: Research Source Type: research

Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study
B vitamins and methionine are essential substrates in the one-carbon metabolism pathway involved in DNA synthesis and methylation. They may have essential roles in cancer development. We aimed to evaluate the ... (Source: BMC Cancer)
Source: BMC Cancer - September 1, 2021 Category: Cancer & Oncology Authors: Paramita Khairan, Tomotaka Sobue, Ehab Salah Eshak, Ling Zha, Tetsuhisa Kitamura, Norie Sawada, Motoki Iwasaki, Manami Inoue, Taiki Yamaji, Taichi Shimazu, Hiroyasu Iso and Shoichiro Tsugane Tags: Research Source Type: research

Overexpression of UTX promotes tumor progression in Oral tongue squamous cell carcinoma patients receiving surgical resection: a case control study
Ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX) has been identified as a histone 3 lysine 27 (H3K27) demethylase and acted as a tumor suppressor gene or oncogenic function. The current ... (Source: BMC Cancer)
Source: BMC Cancer - September 1, 2021 Category: Cancer & Oncology Authors: Yen-Hao Chen, Chang-Han Chen, Chih-Yen Chien, Yan-Ye Su, Sheng-Dean Luo and Shau-Hsuan Li Tags: Research Source Type: research

Prognostic model of long-term advanced stage (IIIB-IV) EGFR mutated non-small cell lung cancer (NSCLC) survivors using real-life data
This study develops a prognostic model using real world data to assist clinicians to predict survival... (Source: BMC Cancer)
Source: BMC Cancer - August 31, 2021 Category: Cancer & Oncology Authors: Lourdes Guti érrez, Ana Royuela, Enric Carcereny, Rafael López-Castro, Delvys Rodríguez-Abreu, Bartomeu Massuti, José Luis González-Larriba, Rosario García-Campelo, Joaquim Bosch-Barrera, María Guirado, Carlos Camps, Manuel Dómine, Reyes Bernabé, Tags: Research Source Type: research

Vascular endothelial growth factor-A is an Immunohistochemical biomarker for the efficacy of bevacizumab-containing chemotherapy for duodenal and jejunal adenocarcinoma
The efficacy and safety of bevacizumab-containing chemotherapy for patients with metastatic duodenal and jejunal adenocarcinoma (mDJA) are unclear. The present study aimed to evaluate the efficacy of bevacizum... (Source: BMC Cancer)
Source: BMC Cancer - August 31, 2021 Category: Cancer & Oncology Authors: Takahiro Amano, Hideki Iijima, Shinichiro Shinzaki, Taku Tashiro, Shuko Iwatani, Mizuki Tani, Yuriko Otake, Takeo Yoshihara, Aya Sugimoto, Satoshi Egawa, Shinjiro Yamaguchi, Kazuo Kinoshita, Manabu Araki, Motohiro Hirao, Yuko Sakakibara, Satoshi Hiyama & Tags: Research Source Type: research

Construction of a ceRNA network of hub genes affecting immune infiltration in ovarian cancer identified by WGCNA
Ovarian cancer is the leading cause of death among gynecological malignancies. Immunotherapy has demonstrated potential effects in ovarian cancer. However, few studies on immune-related prognostic signatures i... (Source: BMC Cancer)
Source: BMC Cancer - August 30, 2021 Category: Cancer & Oncology Authors: Rongjia Su, Chengjuan Jin, Lina Zhou, Yannan Cao, Menghua Kuang, Linxia Li and Jiangdong Xiang Tags: Research article Source Type: research