Effect of tumour size ratio on liver recurrence-free survival of patients undergoing hepatic resection for colorectal liver metastases
The study aimed to assess the impact of size differences of multiple liver metastases on liver recurrence-free survival (RFS) in patients undergoing hepatic resection for colorectal liver metastases (CRLMs). (Source: BMC Cancer)
Source: BMC Cancer - January 25, 2022 Category: Cancer & Oncology Authors: Yana Zhai, Weijun Bai, Jin Zhou, Qian Dong and Jingdong Zhang Tags: Research article Source Type: research

The mixed blessing of AMPK signaling in Cancer treatments
Nutrient acquisition and metabolism pathways are altered in cancer cells to meet bioenergetic and biosynthetic demands. A major regulator of cellular metabolism and energy homeostasis, in normal and cancer cel... (Source: BMC Cancer)
Source: BMC Cancer - January 25, 2022 Category: Cancer & Oncology Authors: Mehrshad Sadria, Deokhwa Seo and Anita T. Layton Tags: Research Source Type: research

An observational study of workflows to support fecal testing for colorectal cancer screening in primary care practices serving Medicaid enrollees
Screening supports early detection and treatment of colorectal cancer (CRC). Provision of fecal immunochemical tests/fecal occult blood tests (FIT/FOBT) in primary care can increase CRC screening, particularly... (Source: BMC Cancer)
Source: BMC Cancer - January 25, 2022 Category: Cancer & Oncology Authors: Cynthia M. Mojica, Rose Gunn, Robyn Pham, Edward J. Miech, Ann Romer, Stephanie Renfro, Khaya D. Clark and Melinda M. Davis Tags: Research article Source Type: research

Identification of TIMELESS and RORA as key clock molecules of non-small cell lung cancer and the comprehensive analysis
The incidence rate of non-small cell lung cancer (NSCLC) has been increasing worldwide, and the correlation of circadian rhythm disruption with a raised risk of cancer and worse prognosis has been shown by acc... (Source: BMC Cancer)
Source: BMC Cancer - January 25, 2022 Category: Cancer & Oncology Authors: Haocheng Xian, Yuan Li, Boliang Zou, Yajuan Chen, Houqing Yin, Xuejun Li and Yan Pan Tags: Research Source Type: research

Lympho-vascular invasion impacts the prognosis in breast-conserving surgery: a systematic review and meta-analysis
It is estimated that breast cancer (BC) incidence, especially that of early-stage breast cancer cases continues to rise due to increased universal screening. Breast-conserving surgery (BCS) is the main interve... (Source: BMC Cancer)
Source: BMC Cancer - January 25, 2022 Category: Cancer & Oncology Authors: Yi-Ming Zhong, Fei Tong and Jun Shen Tags: Research Source Type: research

Correction to: Guy ’s and St Thomas NHS Foundation active surveillance prostate cancer cohort: a characterisation of a prostate cancer active surveillance database
An amendment to this paper has been published and can be accessed via the original article. (Source: BMC Cancer)
Source: BMC Cancer - January 24, 2022 Category: Cancer & Oncology Authors: Salonee Shah, Kerri Beckmann, Mieke Van Hemelrijck, Ben Challacombe, Rick Popert, Prokar Dasgupta, Jonah Rusere, Grace Zisengwe, Oussama Elhage and Aida Santaolalla Tags: Correction Source Type: research

The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy
The gut microbiome is implicated as a marker of response to   immune checkpoint inhibitors (ICI) based on preclinical mouse models and preliminary observations in limited patient series. Furthermore, early stud... (Source: BMC Cancer)
Source: BMC Cancer - January 24, 2022 Category: Cancer & Oncology Authors: Nicola A. Thompson, Grant D. Stewart, Sarah J. Welsh, Gary J. Doherty, Matthew J. Robinson, B. Anne Neville, Kevin Vervier, Simon R. Harris, David J. Adams, Katy Dalchau, David Bruce, Nikolaos Demiris, Trevor D. Lawley and Pippa G. Corrie Tags: Study protocol Source Type: research

Sequential azacitidine and carboplatin induces immune activation in platinum-resistant high-grade serous ovarian cancer cell lines and primes for checkpoint inhibitor immunotherapy
Platinum chemoresistance results in high-grade serous ovarian cancer (HGSOC) disease recurrence. Recent treatment advances using checkpoint inhibitor immunotherapy has not benefited platinum-resistant HGSOC. I... (Source: BMC Cancer)
Source: BMC Cancer - January 24, 2022 Category: Cancer & Oncology Authors: Michelle W. Wong-Brown, Andre van der Westhuizen and Nikola A. Bowden Tags: Research Source Type: research

Effect of prior antibiotic or chemotherapy treatment on immunotherapy response in non-small cell lung cancer
Treatment outcomes of advanced non-small cell lung cancer (NSCLC) have substantially improved with immune checkpoint inhibitors (ICI), although only approximately 19% of patients respond to immunotherapy alone... (Source: BMC Cancer)
Source: BMC Cancer - January 24, 2022 Category: Cancer & Oncology Authors: Andrew F. Nyein, Shahla Bari, Stephanie Hogue, Yayi Zhao, Bradley Maller, Sybil Sha, Maria F. Gomez, Dana E. Rollison and Lary A. Robinson Tags: Research Source Type: research

Dose-escalation by hypofractionated simultaneous integrated boost IMRT in unresectable stage III non-small-cell lung cancer
To explore the maximum tolerated dose (MTD) and evaluate the safety of dose escalation using hypofractionated simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) concurrent with chemother... (Source: BMC Cancer)
Source: BMC Cancer - January 22, 2022 Category: Cancer & Oncology Authors: Qin Zhang, Xu-Wei Cai, Wen Feng, Wen Yu and Xiao-Long Fu Tags: Research Source Type: research

Extracellular vesicles mediated proinflammatory macrophage phenotype induced by radiotherapy in cervical cancer
Radiotherapy is a highly effective treatment for cervical cancer. Recent studies focused on the radiotherapy induced anti-tumor immunity. Whether tumor-derived extracellular vesicles (EVs) play roles in radiot... (Source: BMC Cancer)
Source: BMC Cancer - January 21, 2022 Category: Cancer & Oncology Authors: Junli Ren, Lili Li, Baofeng Yu, Enwei Xu, Naiping Sun, Xiaoning Li, Zihan Xing, Xiaodong Han, Yaqin Cui, Xiaoyan Wang, Xiaoxue Zhang and Guoliang Wang Tags: Research Source Type: research

Metabolic phenotypes and risk of colorectal cancer: a systematic review and meta-analysis of cohort studies
The association of obesity with colorectal cancer (CRC) may vary depending on metabolic status. (Source: BMC Cancer)
Source: BMC Cancer - January 21, 2022 Category: Cancer & Oncology Authors: Golnoosh Goodarzi, Hadis Mozaffari, Tahereh Raeisi, Fatemeh Mehravar, Bahman Razi, Maryam Lafzi Ghazi, Nazila Garousi, Shahab Alizadeh and Parisa Janmohammadi Tags: Research Source Type: research

Statin use is associated with the reduction in hepatocellular carcinoma recurrence after liver surgery
Hepatocellular carcinoma (HCC) is the sixth most common form of cancer worldwide. Although surgical treatments have an acceptable cure rate, tumor recurrence is still a challenging issue. In this meta-analysis... (Source: BMC Cancer)
Source: BMC Cancer - January 21, 2022 Category: Cancer & Oncology Authors: Elias Khajeh, Arash Dooghaie Moghadam, Pegah Eslami, Sadeq Ali-Hasan-Al-Saegh, Ali Ramouz, Saeed Shafiei, Omid Ghamarnejad, Sepehr Abbasi Dezfouli, Christian Rupp, Christoph Springfeld, Carlos Carvalho, Pascal Probst, Seyed Mostafa Mousavizadeh and Ariane Tags: Research Source Type: research

Fibrinogen/albumin ratio as a promising predictor of platinum response and survival in ovarian clear cell carcinoma
This study aims to evaluate the role of the fibrinogen/albumin ratio (FAR) in predicting platinum resistance and survival outcomes of patients with ovarian clear cell carcinoma (OCCC). (Source: BMC Cancer)
Source: BMC Cancer - January 21, 2022 Category: Cancer & Oncology Authors: Wei Chen, Boer Shan, Shuling Zhou, Huijuan Yang and Shuang Ye Tags: Research Source Type: research

Serum cholinesterase may independently predict prognosis in non-small-cell lung cancer
Serum cholinesterase (ChE) was found to be involved in cancer initiation and progression. However, the survival association between serum ChE and non-small cell lung cancer (NSCLC) has not been extensively dis... (Source: BMC Cancer)
Source: BMC Cancer - January 21, 2022 Category: Cancer & Oncology Authors: Hailiang Ran, Jie Ma, Le Cai, Hai Zhou, Zhongqin Yuan, Ying Chen, Wei Chang, Yunchao Huang and Yuanyuan Xiao Tags: Research Source Type: research

Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma
Cancer cells prefer utilizing aerobic glycolysis in order to exacerbate tumor mass and maintain un-regulated proliferative rates. As a key glycolytic activator, phosphofructo-2-kinase/fructose-2,6-bisphosphata... (Source: BMC Cancer)
Source: BMC Cancer - January 20, 2022 Category: Cancer & Oncology Authors: Jun Li, Shiqiang Zhang, Dingzhun Liao, Qian Zhang, Chujie Chen, Xiangwei Yang, Donggen Jiang and Jun Pang Tags: Research Source Type: research

Identification of an ACK1/TNK2-based prognostic signature for colon cancer to predict survival and inflammatory landscapes
Activated Cdc42-associated kinase 1 (ACK1), a kind of tyrosine kinase, is considered to be an oncogene in many cancers, and it is likely to become a potential target for cancer treatment. We found that the exp... (Source: BMC Cancer)
Source: BMC Cancer - January 20, 2022 Category: Cancer & Oncology Authors: Defeng Kong, Guoliang Li, Zhenrong Yang, Shujun Cheng, Wen Zhang, Lin Feng and Kaitai Zhang Tags: Research Source Type: research

Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content
Circulating cell-free DNA (cfDNA) in the plasma of cancer patients contains cell-free tumour DNA (ctDNA) derived from tumour cells and it has been widely recognized as a non-invasive source of tumour DNA for d... (Source: BMC Cancer)
Source: BMC Cancer - January 20, 2022 Category: Cancer & Oncology Authors: Devika Ganesamoorthy, Alan James Robertson, Wenhan Chen, Michael B. Hall, Minh Duc Cao, Kaltin Ferguson, Sunil R. Lakhani, Katia Nones, Peter T. Simpson and Lachlan J. M. Coin Tags: Research article Source Type: research

Modulation of chemoimmunotherapy efficacy in non-small cell lung cancer by sex and histology: a real-world, patient-level analysis
It has been postulated that patient ’s sex impacts response to immunotherapy. Sex modulation of immunotherapy benefit, however, has not yet been explored using patient-level data, where potential confounders, a... (Source: BMC Cancer)
Source: BMC Cancer - January 19, 2022 Category: Cancer & Oncology Authors: Stephanie Tuminello, Naomi Alpert, Rajwanth R. Veluswamy, Arvind Kumar, Jorge E. Gomez, Raja Flores and Emanuela Taioli Tags: Research Source Type: research

Alpha-1 antitrypsin deficiency and risk of lung cancer in never-smokers: a multicentre case –control study
Lung cancer (LC) is the most commonly diagnosed cancer and the leading cause of cancer-related death in both sexes worldwide. Although the principal risk factor in the western world is tobacco smoking, genetic... (Source: BMC Cancer)
Source: BMC Cancer - January 19, 2022 Category: Cancer & Oncology Authors: Ram ón Antonio Tubío-Pérez, María Torres-Durán, María Esmeralda García-Rodríguez, Cristina Candal-Pedreira, Julia Rey-Brandariz, Mónica Pérez-Ríos, Juan Barros-Dios, Alberto Fernández-Villar and Alberto Ruano-Raviña Tags: Research Source Type: research

The role of liver resection in metastatic nephroblastoma: a systematic review and Meta-regression analysis
The impact of hepatic resection for liver metastases (LM) on the survival of pediatric patients with Wilms ’ tumor (WT) is unclear. So far, there is a lack of studies investigating the best suited treatment for... (Source: BMC Cancer)
Source: BMC Cancer - January 18, 2022 Category: Cancer & Oncology Authors: Juri Fuchs, Anastasia Murtha-Lemekhova, Markus Kessler, Patrick G ünther and Katrin Hoffmann Tags: Research Source Type: research

High expression of S100A2 predicts poor prognosis in patients with endometrial carcinoma
S100A2, a member of the S100 protein family, is abnormally expressed and plays a vital role in multiple cancers. However, little is known about the clinical significance of S100A2 in endometrial carcinoma. (Source: BMC Cancer)
Source: BMC Cancer - January 18, 2022 Category: Cancer & Oncology Authors: Qinzhen Zhang, Tianxiang Xia, Chenxiang Qi, Jun Du and Chunping Ye Tags: Research Source Type: research

HoSAGE: sarcopenia in older patient with intermediate / high-risk prostate cancer, prevalence and incidence after androgen deprivation therapy: study protocol for a cohort trial
Sarcopenia is defined by a loss of muscle strength associated to a decrease in skeletal muscle mass. Ageing greatly contributes to sarcopenia as may many other factors such as cancer or androgen deprivation th... (Source: BMC Cancer)
Source: BMC Cancer - January 18, 2022 Category: Cancer & Oncology Authors: Anne-Laure Couderc, Patrick Villani, Julie Berbis, Emilie Nouguer ède, Dominique Rey, Dominique Rossi, Éric Lechevallier, Delphine Badinand, Cyrille Bastide, Gilles Karsenty, Romain Boissier, Kahena Amichi and Xavier Muracciole Tags: Study protocol Source Type: research

Radiosynthesis of a novel antisense imaging probe targeting LncRNA HOTAIR in malignant glioma
Long non-coding RNA (LncRNA) HOTAIR was amplified and overexpressed in many human carcinomas, which could serve as a useful target for cancer early detection and treatment. The 99mTc radiolabeled antisense oligon... (Source: BMC Cancer)
Source: BMC Cancer - January 18, 2022 Category: Cancer & Oncology Authors: Jiongyu Ren, Xiyuan Zhang, Jiang Cao, Jiali Tian, Jin Luo, Yaping Yu, Fengkui Wang and Qian Zhao Tags: Research Source Type: research

Microsatellite instability is biased in Amsterdam II-defined Lynch-related cancer cases with family history but is rare in other cancers: a summary of 1000 analyses
Microsatellite instability (MSI) is a key marker for predicting the response of immune checkpoint inhibitors (ICIs) and for screening Lynch syndrome (LS). (Source: BMC Cancer)
Source: BMC Cancer - January 17, 2022 Category: Cancer & Oncology Authors: Hiroyuki Matsubayashi, Satomi Higashigawa, Yoshimi Kiyozumi, Takuma Oishi, Keiko Sasaki, Hirotoshi Ishiwatari, Kenichiro Imai, Kinichi Hotta, Yohei Yabuuchi, Kazuma Ishikawa, Tatsunori Satoh, Hiroyuki Ono, Akiko Todaka, Takeshi Kawakami, Hiromichi Shirasu Tags: Research Source Type: research

Two novel prognostic models for ovarian cancer respectively based on ferroptosis and necroptosis
Platinum-resistant cases account for 25% of ovarian cancer patients. Our aim was to construct two novel prognostic models based on gene expression data respectively from ferroptosis and necroptosis, for predic... (Source: BMC Cancer)
Source: BMC Cancer - January 17, 2022 Category: Cancer & Oncology Authors: Yang Li, Xiaojin Gong, Tongxiu Hu and Yurong Chen Tags: Research Source Type: research

NSAID use and unnatural deaths after cancer diagnosis: a nationwide cohort study in Sweden
Cancer patients experience increased risk of death from accident and suicide. Cognitive impairment induced by cancer-related inflammation and stress-related psychiatric symptoms may be underlying mechanisms. W... (Source: BMC Cancer)
Source: BMC Cancer - January 17, 2022 Category: Cancer & Oncology Authors: Qing Shen, Arvid Sj ölander, Erica K. Sloan, Adam K. Walker, Katja Fall, Unnur Valdimarsdottir, Pär Sparén, Karin E. Smedby and Fang Fang Tags: Research Source Type: research

Women ’s health behaviour change after receiving breast cancer risk estimates with tailored screening and prevention recommendations
The Predicting Risk of Cancer at Screening (PROCAS) study provided women who were eligible for breast cancer screening in Greater Manchester (United Kingdom) with their 10-year risk of breast cancer, i.e., low... (Source: BMC Cancer)
Source: BMC Cancer - January 16, 2022 Category: Cancer & Oncology Authors: Linda Rainey, Dani ëlle van der Waal, Louise S. Donnelly, Jake Southworth, David P. French, D. Gareth Evans and Mireille J. M. Broeders Tags: Research Source Type: research

An estimate of rate of deviation from NCCN guideline recommendations for central nervous system imaging in trials forming basis for drug approval in first line advanced non-small cell lung cancer (NSCLC)
It is unknown whether and to what degree trials submitted to the US FDA to support drug approval adhere to NCCN guideline-recommended care in their baseline and surveillance CNS imaging protocols. (Source: BMC Cancer)
Source: BMC Cancer - January 16, 2022 Category: Cancer & Oncology Authors: John Sharp and Vinay Prasad Tags: Research Source Type: research

Comparison of surgical outcomes and prognosis between wedge resection and simple Segmentectomy for GGO diameter between 2  cm and 3 cm in non-small cell lung cancer: a multicenter and propensity score matching analysis
As segmentectomy had become commonly used for Non-Small Cell Lung Cancer (NSCLC) treatment, which had the advantages of radical operation, however, it remains controversial owing to procedural complexity and r... (Source: BMC Cancer)
Source: BMC Cancer - January 16, 2022 Category: Cancer & Oncology Authors: Yaodong Zhou, Tao Yu, Yixin Zhang, Liqiang Qian and Qing Xia Tags: Research Source Type: research

SMAD4 –201 transcript as a putative biomarker in colorectal cancer
Transcripts with alternative 5 ′-untranslated regions (UTRs) result from the activity of alternative promoters and they can determine gene expression by influencing its stability and translational efficiency, t... (Source: BMC Cancer)
Source: BMC Cancer - January 16, 2022 Category: Cancer & Oncology Authors: Tamara Babic, Sandra Dragicevic, Marko Miladinov, Zoran Krivokapic and Aleksandra Nikolic Tags: Research Source Type: research

Polygenic risk prediction models for colorectal cancer: a systematic review
Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with o... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2022 Category: Cancer & Oncology Authors: Michele Sassano, Marco Mariani, Gianluigi Quaranta, Roberta Pastorino and Stefania Boccia Tags: Research Source Type: research

Health-related quality of life in women with breast cancer: a review of measures
To identify and describe the breast cancer –specific health-related quality of life (HRQoL) instruments with evidence of validation in the breast cancer population for potential use in patients treated for brea... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2022 Category: Cancer & Oncology Authors: Maribel Salas, Margaret Mordin, Colleen Castro, Zahidul Islam, Nora Tu and Michelle D. Hackshaw Tags: Research article Source Type: research

THUNDER 2: THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI guided radiotherapy
Neoadjuvant chemoradiation therapy (nCRT) is the standard treatment modality in locally advanced rectal cancer (LARC). Since response to radiotherapy (RT) is dose dependent in rectal cancer, dose escalation ma... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2022 Category: Cancer & Oncology Authors: Giuditta Chiloiro, Davide Cusumano, Luca Boldrini, Angela Romano, Lorenzo Placidi, Matteo Nardini, Elisa Meldolesi, Brunella Barbaro, Claudio Coco, Antonio Crucitti, Roberto Persiani, Lucio Petruzziello, Riccardo Ricci, Lisa Salvatore, Luigi Sofo, Sergio Tags: Study protocol Source Type: research

Core promoter mutation contributes to abnormal gene expression in bladder cancer
Bladder cancer is one of the most mortal cancers. Bladder cancer has distinct gene expression signature, highlighting altered gene expression plays important roles in bladder cancer etiology. However, the mech... (Source: BMC Cancer)
Source: BMC Cancer - January 15, 2022 Category: Cancer & Oncology Authors: Teng Huang, Jiaheng Li and San Ming Wang Tags: Research Source Type: research

An exploration of immunohistochemistry-based prognostic markers in patients undergoing curative resections for colon cancer
The immune system recognizes and destroys cancer cells. However, cancer cells develop mechanisms to avoid detection by expressing cell surface proteins. Specific tumour cell surface proteins (e.g. HLA-G, PD-L1... (Source: BMC Cancer)
Source: BMC Cancer - January 14, 2022 Category: Cancer & Oncology Authors: Astrid Louise Bj ørn Bennedsen, Luyi Cai, Rune Petring Hasselager, Aysun Avci Özcan, Khadra Bashir Mohamed, Jens Ole Eriksen, Susanne Eiholm, Michael Bzorek, Anne-Marie Kanstrup Fiehn, Thomas Vauvert F. Hviid and Ismail Gögenur Tags: Research Source Type: research

Inflammation-scores as prognostic markers of overall survival in lung cancer: a register-based study of 6,210 Danish lung cancer patients
Inflammation-scores based on general inflammation markers are suggested as prognostic markers of overall survival (OS) in lung cancer. However, whether these inflammation-scores improves the prognostication pe... (Source: BMC Cancer)
Source: BMC Cancer - January 14, 2022 Category: Cancer & Oncology Authors: Anne Winther-Larsen, Ninna Aggerholm-Pedersen and Birgitte Sandfeld-Paulsen Tags: Research Source Type: research

Neutrophil-to-lymphocyte ratio as a prognostic factor for patients with metastatic or recurrent breast cancer treated using capecitabine: a retrospective study
Eribulin or capecitabine monotherapy is the next cytotoxic chemotherapy option for patients with metastatic or recurrent breast cancer who have previously received an anthracycline or a taxane. However, it is ... (Source: BMC Cancer)
Source: BMC Cancer - January 14, 2022 Category: Cancer & Oncology Authors: Shigemasa Takamizawa, Tatsunori Shimoi, Natsuko Satomi-Tsushita, Shu Yazaki, Toshihiro Okuya, Yuki Kojima, Hitomi Sumiyoshi-Okuma, Tadaaki Nishikawa, Maki Tanioka, Kazuki Sudo, Emi Noguchi and Kan Yonemori Tags: Research Source Type: research

Prognostic significance of long non-coding RNA five prime to XIST in various cancers
To observe the clinicopathological and prognostic value of long non-coding RNA five prime to X inactive specific transcript (lncFTX) in multiple tumors. (Source: BMC Cancer)
Source: BMC Cancer - January 13, 2022 Category: Cancer & Oncology Authors: Jian Zhou, Junjie Chen, Ziyuan Chen, Gen Wu, Zhen Zhou, Tong Wu, Wanchun Wang, Yingquan Luo and Tang Liu Tags: Research Source Type: research

The non-fatal burden of cancer in Belgium, 2004 –2019: a nationwide registry-based study
The importance of assessing and monitoring the health status of a population has grown in the last decades. Consistent and high quality data on the morbidity and mortality impact of a disease represent the key... (Source: BMC Cancer)
Source: BMC Cancer - January 13, 2022 Category: Cancer & Oncology Authors: Vanessa Gorasso, Geert Silversmit, Marc Arbyn, Astrid Cornez, Robby De Pauw, Delphine De Smedt, Ian Grant, Grant M. A. Wyper, Brecht Devleesschauwer and Niko Speybroeck Tags: Research Source Type: research

Clinical significance of metabolism-related genes and FAK activity in ovarian high-grade serous carcinoma
Administration of poly (ADP-ribose) polymerase (PARP) inhibitors after achieving a response to platinum-containing drugs significantly prolonged relapse-free survival compared to placebo administration. PARP i... (Source: BMC Cancer)
Source: BMC Cancer - January 13, 2022 Category: Cancer & Oncology Authors: Masakazu Sato, Sho Sato, Daisuke Shintani, Mieko Hanaoka, Aiko Ogasawara, Maiko Miwa, Akira Yabuno, Akira Kurosaki, Hiroyuki Yoshida, Keiichi Fujiwara and Kosei Hasegawa Tags: Research Source Type: research

Nanoparticle albumin-bound paclitaxel and PD-1 inhibitor (sintilimab) combination therapy for soft tissue sarcoma: a retrospective study
There is increasing evidence that combination therapy with nanoparticle albumin-bound paclitaxel (nab-paclitaxel) and programmed cell death protein 1 (PD-1) inhibitor is safe and efficacious in treating many t... (Source: BMC Cancer)
Source: BMC Cancer - January 12, 2022 Category: Cancer & Oncology Authors: Zhichao Tian, Shuping Dong, Yang Yang, Shilei Gao, Yonghao Yang, Jinpo Yang, Peng Zhang, Xin Wang and Weitao Yao Tags: Research Source Type: research

The mediator role of resilience between psychological predictors and health-related quality of life in breast cancer survivors: a cross-sectional study
Although many psychological factors have been associated with health-related quality of life (HRQoL), the mediator role of resilience between psychological predictors (i.e., coping styles and perceived social ... (Source: BMC Cancer)
Source: BMC Cancer - January 12, 2022 Category: Cancer & Oncology Authors: Kaina Zhou, Fan Ning, Wen Wang and Xiaomei Li Tags: Research Source Type: research

Anti-PD-1 combined sorafenib versus anti-PD-1 alone in the treatment of advanced hepatocellular cell carcinoma: a propensity score-matching study
Vascular endothelial growth factor (VEGF) plays a role in the tumor microenvironment. Sorafenib, which inhibits the VEGF pathway, has an immune-modulation function but lacks substantial clinical data. This stu... (Source: BMC Cancer)
Source: BMC Cancer - January 11, 2022 Category: Cancer & Oncology Authors: San-Chi Chen, Yi-Hsiang Huang, Ming-Huang Chen, Yi-Ping Hung, Rheun-Chuan Lee, Yu-Yun Shao and Yee Chao Tags: Research Source Type: research

Variable roles of interleukin-17F in different cancers
Interleukin (IL)-17 family is a group of six cytokines that plays a central role in inflammatory processes and participates in cancer progression. Interleukin-17A has been shown to have mainly a protumorigenic... (Source: BMC Cancer)
Source: BMC Cancer - January 11, 2022 Category: Cancer & Oncology Authors: Tiina Mikkola, Rabeia Almahmoudi, Tuula Salo and Ahmed Al-Samadi Tags: Research Source Type: research

Characterization of surface markers on extracellular vesicles isolated from lymphatic exudate from patients with breast cancer
Breast cancer is the most common cancer, and the leading cause of cancer-related deaths, among females world-wide. Recent research suggests that extracellular vesicles (EVs) play a major role in the developmen... (Source: BMC Cancer)
Source: BMC Cancer - January 10, 2022 Category: Cancer & Oncology Authors: Karin Ekstr öm, Rossella Crescitelli, Hafsteinn Ingi Pétursson, Junko Johansson, Cecilia Lässer and Roger Olofsson Bagge Tags: Research Source Type: research

Checkpoint inhibitors in metastatic gastric and GEJ cancer: a multi-institutional retrospective analysis of real-world data in a Western cohort
Safety and efficacy of immune checkpoint inhibitors in advanced gastric or gastroesophageal junction (GEJ) cancer could be demonstrated in predominantly Asian cohorts, whereas data in Western patients outside ... (Source: BMC Cancer)
Source: BMC Cancer - January 10, 2022 Category: Cancer & Oncology Authors: Verena Schlintl, Florian Huemer, Gabriel Rinnerthaler, Thomas Melchardt, Thomas Winder, Patrick Reimann, Jakob Riedl, Arno Amann, Wolfgang Eisterer, Franz Romeder, Gudrun Piringer, Ayseg ül Ilhan-Mutlu, Ewald Wöll, Richard Greil and Lukas Weiss Tags: Research article Source Type: research

Meta-analysis of health state utility values measured by EuroQol 5-dimensions (EQ5D) questionnaire in Chinese women with breast cancer
To synthesise EQ5D health state utility values in Chinese women with breast cancer for parameterising a cost utility model. (Source: BMC Cancer)
Source: BMC Cancer - January 10, 2022 Category: Cancer & Oncology Authors: Tamlyn Rautenberg, Brent Hodgkinson, Ute Zerwes and Martin Downes Tags: Research article Source Type: research

Exercise-based dysphagia rehabilitation for adults with oesophageal cancer: a systematic review
Dysphagia is prevalent in oesophageal cancer with significant clinical and psychosocial complications. The purpose of this study was i) to examine the impact of exercise-based dysphagia rehabilitation on clini... (Source: BMC Cancer)
Source: BMC Cancer - January 10, 2022 Category: Cancer & Oncology Authors: Anna Gillman, Michelle Hayes, Greg Sheaf, Margaret Walshe, John V. Reynolds and Julie Regan Tags: Research article Source Type: research

Preemptive pharmacogenetic testing to guide chemotherapy dosing in patients with gastrointestinal malignancies: a qualitative study of barriers to implementation
Pharmacogenetic (PGx) testing for germline variants in the DPYD and UGT1A1 genes can be used to guide fluoropyrimidine and irinotecan dosing, respectively. Despite the known association between PGx variants and c... (Source: BMC Cancer)
Source: BMC Cancer - January 8, 2022 Category: Cancer & Oncology Authors: Kelsey S. Lau-Min, Lisa A. Varughese, Maria N. Nelson, Christine Cambareri, Nandi J. Reddy, Randall A. Oyer, Ursina R. Teitelbaum and Sony Tuteja Tags: Research Source Type: research