Predictive values of relative fat mass and body mass index on cardiovascular health in community-dwelling older adults: Results from the Longevity Check-up (Lookup) 7+
Cardiovascular disease (CVD) is the leading cause of death and non-communicable diseases worldwide [1,2]. Cardiovascular risk factors (CRFs) such as excess body weight, high blood pressure (BP), diabetes, high low-density lipoprotein cholesterol, and active smoking are responsible for more than half of new CVD diagnoses and one fifth of 10-year mortality [3]. Assessing and managing cardiovascular risk is particularly relevant in older adults, as advancing age itself is a predisposing factor for CVD [4]. (Source: Maturitas)
Source: Maturitas - May 1, 2024 Category: Primary Care Authors: Stefano Cacciatore, Riccardo Calvani, Emanuele Marzetti, Helio Jos é Coelho-Júnior, Anna Picca, Alberto Emanuele Fratta, Ilaria Esposito, Matteo Tosato, Francesco Landi Tags: Original article Source Type: research
IJERPH, Vol. 21, Pages 581: Behind the Hospital Ward: In-Hospital Mortality of Type 2 Diabetes Mellitus Patients in Indonesia (Analysis of National Health Insurance Claim Sample Data)
This study examined in-hospital mortality among patients diagnosed with non-insulin-dependent diabetes mellitus (NIDDM) of ICD-10, or Type 2 Diabetes Mellitus (T2DM), in Indonesia, utilizing hospital claims data spanning from 2017 to 2022 obtained from the Indonesia Health Social Security Agency or Badan Penyelenggara Jaminan Sosial (BPJS) Kesehatan. The analysis, which included 610,809 hospitalized T2DM patients, revealed an in-hospital mortality rate of 6.6%. Factors contributing to an elevated risk of mortality included advanced age, the presence of comorbidities, and severe complications. Additionally, patients receivi...
Source: International Journal of Environmental Research and Public Health - May 1, 2024 Category: Environmental Health Authors: Ede Surya Darmawan Vetty Yulianty Permanasari Latin Vania Nisrina Dian Kusuma Syarif Rahman Hasibuan Nisrina Widyasanti Tags: Article Source Type: research
Protective potential of laughter yoga and clapping exercises on stress level and motor functions in Parkinson ’s disease patients with type 2 diabetes
Background: To examine the protective potential of laughter yoga and clapping exercise on blood glucose regulation on stress level and motor functions of Parkinson ’s disease (PD) patients with type 2 diabetes mellitus (T2DM). (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: R. Kumar, R. Singh, V. Sharma Source Type: research
The clinical features, neuroimaging and outcomes of diabetic striatopathy: A retrospective study at a tertiary hospital in Vietnam
Background: Diabetic striatopathy (DS) is a rare heterogeneous disease characterized by chorea/ballism and unique reversible lesions on brain imaging in hyperglycemic patients. Previous reports were in the form of case reports or small sample case series reports making them difficult. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: N. Nguyen, K. Nguyen, K. Le, T. Tran Source Type: research
Role of linagliptin, a dipeptidyl peptidase-4 inhibitor against oxidative stress and neuronal damage in experimental diabetic aging brain of female rats of different age groups.
Background: Linagliptin, a specific inhibitor of the dipeptidyl peptidase-4 (DPP-4) inhibitors, an enzyme that degrades two incretin hormones, GLP1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: P. Kumar, N. Baquer Source Type: research
Cancers, Vol. 16, Pages 1764: Endocrine Immune-Related Adverse Events Are Independent Predictors of Survival in Patients with Lung Cancer
Melpomeni Peppa
Lung cancer (LC) is a serious health problem worldwide. Survival outcomes have improved over time due to the widespread use of novel therapeutic agents, including immune checkpoint inhibitors (ICIs). Endocrine immune-related adverse events (e-irAEs) are common in LC patients treated with ICIs. We performed a retrospective study of patients with LC who received treatment with ICIs at a tertiary referral center between January 2014 and October 2023. In total, 983 LC patients were included in the study. E-irAEs presented at a median time of 4.1 months and included hypothyroidism (15.6%), hyperthyroidism ...
Source: Cancers - May 1, 2024 Category: Cancer & Oncology Authors: Emmanouil Panagiotou Sofia Ntouraki Ioannis A. Vathiotis Maria Effrosyni Livanou Athanasios Trimis Georgios Evangelou Andriani Charpidou Konstantinos Syrigos Melpomeni Peppa Tags: Article Source Type: research
Cancers, Vol. 16, Pages 1760: Real-World Data Analysis of CDK4/6 Inhibitor Therapy & mdash;A Patient-Centric Single Center Study
Conclusions: These findings emphasize the importance of tailored treatment strategies, highlighting the role of PR expression, metastatic burden, and therapeutic adjustments in optimizing patient outcomes in real-world breast cancer management. (Source: Cancers)
Source: Cancers - May 1, 2024 Category: Cancer & Oncology Authors: Isabell Ge Kai Berner Marlene Mathis Catherine Hensgen Sebastian Mayer Thalia Erbes Ingolf Juhasz-B öss Jasmin Asberger Tags: Article Source Type: research
Are Poor Outcomes Always a Surgeon's Complication?
Many lectures I hear on the regional and national level focus on complications, failures, and risk factors in oral and maxillofacial surgery. However, as I look at my own cases and the presented cases, there is sometimes, and often, an underlying cause. Poor host responses, such as systemic medical conditions, local disease or inflammation, or unhealthy habits, can all contribute to increased complication rates. For example, it is well documented that diabetics have increased wound infections, dehiscence, and scarring, and coupled with obesity, the risk for postoperative infections is further increased. (Source: Journal of...
Source: Journal of Oral and Maxillofacial Surgery - May 1, 2024 Category: ENT & OMF Authors: Tara Aghaloo Tags: Editorial Source Type: research
Issue Information
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - April 30, 2024 Category: Endocrinology Tags: Issue Information Source Type: research
Effect of the Healthy Dish Method to Reduce Waist Circumference in Teachers with Abdominal Obesity of a Peruvian University
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 30, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Prevalence of Hypertension and Diabetes in Severe COVID-19: A Cross-Sectional Study from Single Center, Kabul
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - April 30, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Construction of Risk Prediction Model of Type 2 Diabetic Kidney Disease Based on Deep Learning
CONCLUSION: The developed DKD risk predictive model using LSTM neural networks demonstrated high accuracy and AUC value. When HbA1c, SBP, and PP variabilities were added to the model as featured characteristics, the model's performance was greatly improved.PMID:38685670 | DOI:10.4093/dmj.2023.0033 (Source: Diabetes and Metabolism Journal)
Source: Diabetes and Metabolism Journal - April 30, 2024 Category: Endocrinology Authors: Chuan Yun Fangli Tang Zhenxiu Gao Wenjun Wang Fang Bai Joshua D Miller Huanhuan Liu Yaujiunn Lee Qingqing Lou Source Type: research
The Impact of the COVID-19 Pandemic on Bell's Palsy and Ramsay-Hunt Syndrome: A Multicenter Retrospective Study
CONCLUSION: This study highlights the impact of the COVID-19 pandemic on the presentation and management of facial palsy, and suggests potential associations with COVID-19. Notably, the observed increase in Bell's palsy cases among elderly individuals with diabetes emphasizes the impact of the pandemic. Identifying the epidemiological changes in facial palsy during the COVID-19 pandemic has important implications for assessing its etiology and pathological mechanisms of facial palsy disease.PMID:38685888 | PMC:PMC11058340 | DOI:10.3346/jkms.2024.39.e140 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 30, 2024 Category: Biomedical Science Authors: Min Young Kwak Ho Yun Lee Se A Lee Junhui Jeong Jae Ho Chung Jin Kim Beom Cho Jun Seung-Geun Yeo Sang Hoon Kim Jong Dae Lee Source Type: research
Hospital-Acquired Acute Kidney Injury in Non-Critical Medical Patients in a Developing Country Tertiary Hospital: Incidence and Predictors
CONCLUSION: HAAKI is a common complication in hospitalized non-critical medical patients, and is associated with a common medical condition and commonly prescribed medications. Therefore, it is important to remain vigilant in the prevention and timely identification of these cases and to establish a system of rational prescribing habits.PMID:38685967 | PMC:PMC11057508 | DOI:10.2147/IJNRD.S454987 (Source: International Journal of Nephrology and Renovascular Disease)
Source: International Journal of Nephrology and Renovascular Disease - April 30, 2024 Category: Urology & Nephrology Authors: Nahom Dessalegn Mekonnen Tigist Workneh Leulseged Buure Ayderuss Hassen Kidus Haile Yemaneberhan Helen Surafeal Berhe Nebiat Adane Mera Anteneh Abera Beyene Lidiya Zenebe Getachew Birukti Gebreyohannes Habtezgi Feven Negasi Abriha Source Type: research
Immunopeptidome mining reveals a novel ERS-induced target in T1D
This study provides not only a new explanation for the role of ERS in promoting β-cell-targeted autoimmunity but also a potential target for the prevention and treatment of T1D. The data are available via ProteomeXchange with the identifier PXD041227.PMID:38689020 | DOI:10.1038/s41423-024-01150-0 (Source: Cellular and Molecular Immunology)
Source: Cellular and Molecular Immunology - April 30, 2024 Category: Molecular Biology Authors: Lina Wang Shushu Yang Gaohui Zhu Jie Li Gang Meng Xiaoling Chen Mengjun Zhang Shufeng Wang Xiangqian Li Yu Pan Yi Huang Li Wang Yuzhang Wu Source Type: research
