Hip and Subtrochanteric or Femoral Shaft Fractures after Bisphosphonate Use in Korean Women, Using Korean National Sample Cohort.
The objective of this study was to evaluate the risk of typical hip fractures and ST/FS fractures among bisphosphonate users using nationwide database. METHODS: We performed a retrospective cohort study using National Health Insurance Service-National Sample Cohort. We evaluated occurrence of the ST/FS and femoral neck and intertrochanteric (FN/IT) fractures among female bisphosphonate new users. Incidence rate of ST/FS and FN/IT fractures were compared between long-term users (≥ 1 year) and short-term users (
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Comparison of Postextubation Outcomes Associated with High-Flow Nasal Cannula vs. Conventional Oxygen Therapy in Patients at High Risk of Reintubation: a Randomized Clinical Trial.
CONCLUSION: Among patients at high risk for reintubation, compared with COT, HFNC did not reduce the risk of reintubation within 72 hours. PMID: 32597041 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

YouTube as a Source of Information and Education on Hysterectomy.
CONCLUSION: YouTube is currently not an appropriate source for patients to gain information on hysterectomy. Physicians should be aware of the limitations and provide up-to-date and peer-reviewed content on the website. PMID: 32597042 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Successful Pregnancy and Delivery with Intracytoplasmic Sperm Injection in HIV-Serodiscordant Couple: the First Case in Korea.
We report a 32-year-old HIV-seronegative female with her husband who was HIV-1 seropositive. After semen washing was performed by means of a density gradient and the swim-up technique, HIV-1 ribonucleic acid was not detected in the semen. An aliquot of processed semen was cryopreserved before ART. None of 3 cycles of intrauterine insemination was successful. After the third frozen-thawed embryo transfer following two cycles of intracytoplasmic sperm injection, an intrauterine singleton pregnancy was identified. She gave birth to a normal healthy male baby at full term by Cesarean section. She and her baby were tested for H...
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Status of Editing and Publishing of Scholarly Journals by Academic Societies of Science and Technology in Korea.
Authors: Hong ST, Youn HS Abstract BACKGROUND: The present study analyzed publishing data of scholarly journals which were published in 2018 by academic societies of science and technology in Korea to observe journal editing and publishing status. METHODS: A total of 346 regional journals (59 natural science, 118 engineering, 44 agriculture, fisheries, and oceanography, and 125 medical and pharmacy) and 141 international journals (32 natural science, 43 engineering, 12 agriculture, fisheries, and oceanography, 54 medical and pharmacy) were included in this analysis, which applied the journal review by the Korea...
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Compliance of Antihypertensive Medication and Risk of Coronavirus Disease 2019: a Cohort Study Using Big Data from the Korean National Health Insurance Service.
CONCLUSION: Renin-angiotensin system blockers or other antihypertensive medications do not increase the risk of COVID-19. Patients should not stop antihypertensive medications, including renin-angiotensin system blockers, because of concerns of COVID-19. PMID: 32597045 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Prognostic Accuracy of the SIRS, qSOFA, and NEWS for Early Detection of Clinical Deterioration in SARS-CoV-2 Infected Patients.
Authors: Jang JG, Hur J, Hong KS, Lee W, Ahn JH Abstract BACKGROUND: The case fatality rate of coronavirus disease 2019 (COVID-19) is estimated to be between 4.3% and 11.0%. Currently there is no effective antiviral treatment for COVID-19. Thus, early recognition of patients at high risk is important. METHODS: We performed a retrospective observational study of 110 patients with severe acute respiratory syndrome coronavirus 2 infection. We compared the effectiveness of three scoring systems: the Systemic Inflammatory Response Syndrome (SIRS), quick Sequential Organ Failure Assessment (qSOFA), and National Early...
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

The Epidemiological and Clinical Characteristics of 81 Children with COVID-19 in a Pandemic Hospital in Turkey: an Observational Cohort Study.
CONCLUSION: Compared to adults, COVID-19 is milder and more distinctive in children. As a result, more conservative approaches might be preferred in children for the diagnostic, clinical, and even therapeutic applications. PMID: 32597047 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Effect of Underlying Comorbidities on the Infection and Severity of COVID-19 in Korea: a Nationwide Case-Control Study.
CONCLUSION: We identified several comorbidities associated with COVID-19. Health care workers should be more careful while diagnosing and treating COVID-19 when patients have the abovementioned comorbidities. PMID: 32597048 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - July 1, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

A Rare Case of Essential Thrombocythemia with Coexisting JAK2 and MPL Driver Mutations.
In this report, we describe the first case of ET harboring double mutations in JAK2 V617F and MPL. For MPL, the patient had multiple clones of MPL mutations: c.1543_1546delinsAGGG (p.Trp515_Gln516delinsArgGlu) and c.1546C>G (p.Gln516Glu). The JAK2 V617F allele burden in our patient is very low (4%) compared to the relatively high (17%-78%) allele frequency of MPL mutations. The low JAK2 mutant burden might be explained by preexisting clonal hematopoiesis before overt signs of MPNs, followed by the acquisition of a second oncogenic mutation of CALR or MPL leading to the MPN phenotype. This highlights that screening for a...
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Intravenous Glucocorticoid Treatment for Korean Graves' Ophthalmopathy Patients.
CONCLUSION: In Korean active moderate-to-severe GO patients, intravenous steroid treatment is not as effective as previously reported. Parameters associated with CAS and soft-tissue involvement were found to be influenced by IV MPD treatment. Extraocular muscle enlargement, younger age and lower TBII are predictive factors for a good steroid treatment response. PMID: 32537950 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Relationship between Clinical Features of Diabetic Retinopathy and Systemic Factors in Patients with Newly Diagnosed Type II Diabetes Mellitus.
Authors: Hwang H, Kim JY, Oh TK, Chae JB, Kim DY Abstract BACKGROUND: We investigated the relationship between clinical features of diabetic retinopathy (DR) and systemic factors in patients with newly diagnosed type II diabetes mellitus (T2DM). METHODS: Retrospective review of newly diagnosed T2DM-patients who underwent complete ophthalmic examinations at the time of T2DM diagnosis were conducted. We reviewed DM related systemic factor data and investigated systemic factors related to the presence of DR at T2DM diagnosis. In DR patients, the relationship between DR severity and systemic factors was analyzed. ...
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Dietary Assessment of Korean Non-dialysis Chronic Kidney Disease Patients with or without Diabetes.
CONCLUSION: DM and kidney function affected energy and nutrient intakes. Subjects in the Late-CKD group consumed less energy than those in the Early-CKD group. Non-DM subjects seemed to restrict protein intake starting from the Early-CKD stage than subjects with DM. Subjects in this study had low energy and high sodium intakes compared with recommended levels. Protein intake was lower in advanced CKD patients, but their intake level was still higher than the recommendation. Dietary intervention strategies for non-dialysis CKD patients need to be customized depending on the presence of DM and kidney function. PMID: 3253...
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Evaluation of Human MSCs Treatment Frequency on Airway Inflammation in a Mouse Model of Acute Asthma.
CONCLUSION: The results of treatment with hADSCs or hBMSCs suppresses AHR and airway inflammation. However, double hMSC treatment significantly induces eosinophilic airway inflammation and lung histological changes. Therefore, double hMSC treatment is ineffective against asthma and single injection frequency appears to be more important for the treatment of asthma. These results suggest that hMSC therapy can be used for treatment of asthma patients but that it should be used carefully. PMID: 32537953 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Prognostic Factors for Severe Coronavirus Disease 2019 in Daegu, Korea.
CONCLUSION: In conclusion, we found that diabetes mellitus, body temperature ≥ 37.8°C, peripheral oxygen saturation 6.3 are independent predictors of severe disease in hospitalized COVID-19 patients. Appropriate assessment of prognostic factors and close monitoring to provide the necessary interventions at the appropriate time in high-risk patients may reduce the case fatality rate of COVID-19. PMID: 32537954 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Social Distancing and Transmission-reducing Practices during the 2019 Coronavirus Disease and 2015 Middle East Respiratory Syndrome Coronavirus Outbreaks in Korea.
CONCLUSION: The study findings suggest markedly increased proportions of non-pharmaceutical behavioral practices evenly across all subgroups during the two different novel virus outbreaks in Korea. Strategic interventions are needed to attempt based on preventive behavior works. PMID: 32537955 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Uncertainty about the Efficacy of Remdesivir on COVID-19.
Authors: Yoo JH PMID: 32537956 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Risk Factors for Mortality and Respiratory Support in Elderly Patients Hospitalized with COVID-19 in Korea.
Authors: Lee JY, Kim HA, Huh K, Hyun M, Rhee JY, Jang S, Kim JY, Peck KR, Chang HH Abstract BACKGROUND: The mortality risk of coronavirus disease 2019 (COVID-19) is higher in patients with older age, and many elderly patients are reported to require advanced respiratory support. METHODS: We reviewed medical records of 98 patients aged ≥ 65 years who were hospitalized with COVID-19 during a regional outbreak in Daegu/Gyeongsangbuk-do province of Korea. The outcome measures were in-hospital mortality and the treatment with mechanical ventilation (MV) or high-flow nasal cannula (HFNC). RESULTS: The median a...
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Impact of the Dedicated Neurointensivists on the Outcome in Patients with Ischemic Stroke Based on the Linked Big Data for Stroke in Korea.
In this study, we aimed to validate whether neurointensive care could improve the outcome in patients with critically ill acute ischemic stroke using the linked big dataset on stroke in Korea. METHODS: We included 1,405 acute ischemic stroke patients with mechanical ventilator support in the intensive care unit after an index stroke. Patients were retrieved from linking the Clinical Research Center for Stroke Registry and the Health Insurance Review and Assessment Service data from the period between January 2007 and December 2014. The outcomes were mortality at discharge and at 3 months after an index stroke. The main...
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Anti-Sm Antibody, Damage Index, and Corticosteroid Use Are Associated with Cardiac Involvement in Systemic Lupus Erythematosus: Data from a Prospective Registry Study.
Authors: Choe JY, Lee SS, Kwak SG, Kim SK Abstract BACKGROUND: Disease-specific factors that predispose patients to diverse cardiac diseases in systemic lupus erythematosus (SLE) have been established. The aim of this study was to identify risk factors for cardiac involvement in patients with SLE drawn from the Korean Lupus Network (KORNET) registry. METHODS: A total of 437 patients with SLE recruited from the KORNET registry were included in the analysis. The Cox proportional hazard model was used to identify risk factors for the development of cardiac involvement during the follow-up period. The hazard ratios...
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Inequalities in Longitudinal Health Trajectories in Middle to Later Life: a Comparison of European Countries and Korea.
CONCLUSION: These findings suggest that it is inconclusive whether Sweden and Denmark (with the most generous welfare arrangements) have better trajectories of health, and Spain, Italy, and Korea (with the least advanced state policies) have worse SRH paths among older adults. However, it can be inferred that Korean governmental policies may have produced a relatively worse context for the less-educated than the six European countries, as well as poorer settings for women than Denmark in terms of their initial SRH status. PMID: 32476301 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Development of a Smartphone-Based Digits-in-Noise Test in Korean: a Hearing Screening Tool for Speech Perception in Noise.
CONCLUSION: We believe this study is the first to attempt to develop a K-DiN test. Our results indicate that this test can be used as a potentially reliable hearing screening tool. PMID: 32476302 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Stress of Low Socioeconomic Status.
Authors: Chung BS PMID: 32476303 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Effects of Sedation Performed by an Anesthesiologist on Pediatric Endoscopy: a Single-Center Retrospective Study in Korea.
Authors: Yang SM, Yi DY, Choi GJ, Lim IS, Chae SA, Yun SW, Lee NM, Kim SY, Choi ES Abstract BACKGROUND: Endoscopy is used for diagnosing and treating various digestive diseases in children as well as in adults. However, in pediatric patients, it is recommended that sufficient sedation should be ensured before conducting endoscopy, since insufficient sedation may cause serious complications. However, in Korea, no studies have yet described the types of sedation drugs, effects of sedation, and efficiency of endoscopy with respect to the sedation instructor. Thus, we investigated the effectiveness of sedative procedur...
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

The Burden of Disease due to COVID-19 in Korea Using Disability-Adjusted Life Years.
CONCLUSION: This study provided the estimates of DALYs due to COVID-19 in Korea. Most of the disease burden from COVID-19 was derived from YLL; this indicates that decision-makers should focus and make an effort on reducing fatality for preparing the second wave of COVID-19. PMID: 32476305 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Olfactory and Gustatory Dysfunction in a COVID-19 Patient with Ankylosing Spondylitis Treated with Etanercept: Case Report.
We report olfactory and gustatory dysfunctions in a patient with ankylosing spondylitis (AS) treated with etanercept during COVID-19. A 53-year-old female showing AS controlled with tumor necrosis factor-α inhibitor, etanercept, had been diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, presenting cough and rhinorrhea. One month after diagnosis, she complained about hyposmia and hypogeusia two days before the seronegative conversion of SARS-CoV-2, which were confirmed by a neurological examination. We speculate that the etanercept may have delayed the development of olfactory and ...
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Erratum: Correction of Author ORCID in the Article: Efficacy of Random-start Controlled Ovarian Stimulation in Cancer Patients.
Authors: Kim JH, Kim SK, Lee HJ, Lee JR, Jee BC, Suh CS, Kim SH Abstract This corrects the article on p. 290 in vol. 30, PMID: 25729252. PMID: 32476307 [PubMed] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - June 3, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Seasonal Variations and Associated Factors of Gout Attacks: a Prospective Multicenter Study in Korea.
Authors: Choi HJ, Moon KW, Kim HO, Lee YA, Hong SJ, Jung JY, Kim HA, Suh CH, Ha YJ, Kim IJ, Lee J, Park EK, Lee SG, Seo MR, Baek HJ, Choi ST, Song JS Abstract BACKGROUND: We purposed to evaluate the seasonality and associated factors of the incidence of gout attacks in Korea. METHODS: We prospectively enrolled patients with gout attacks who were treated at nine rheumatology clinics between January 2015 and July 2018 and followed them for 1-year. Demographic data, clinical and laboratory features, and meteorological data including seasonality were collected. RESULTS: Two hundred-five patients (men, 94.1%) we...
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Syncope after Influenza Virus Infection.
Authors: Noh SM, Kang HG, Kim BJ Abstract Influenza is an epidemical acute respiratory disease caused by viral infection. Several complications in the respiratory tract, such as pneumonia can occur. However, rare but serious neurological complications are also observed. Here, we described the prevalence, characteristics and suggestive pathomechanism of syncope after influenza infection season. Of 2.2% of patients diagnosed as influenza experienced syncope. None of the patients had severe cough, low blood pressure (BP) or dehydration. Patients suffered with frequent dizziness before syncope. Patient with long durati...
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Innovative Strategies for Peer Review.
This article aims to give an overview of the innovative strategies for peer review and to consider perspectives that may be helpful in introducing changes to peer review. Critical assessments of peer review innovations and incentives based on past and present experiences are indispensable. A theoretical appraisal must be balanced by a realistic appraisal of the ethical roles of all stakeholders in enhancing the peer review process. As the peer review system is far from being perfect, identifying and developing core competencies among reviewers, continuing education of researchers, reviewer education and training, and profe...
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Who Are the People Willing to Pay for Physician Home Visits?
CONCLUSION: This study provides evidence that the decision to pay for a physician home visit service is based upon the complex interactions among an individual's physical and psychosocial functioning, personal experiences of service utilization, and demographic factors. The value for physician home visits should be qualified based on the empirical data of WTP, which comes from a consumer-centered perspective. PMID: 32449323 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Risk of Graft Failure in Kidney Recipients with Cured Post-Transplant Cancer.
CONCLUSION: Appropriate monitoring of graft function is necessary in patients with cured PTCs. PMID: 32449324 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Acute Stroke Care in Korea in 2013-2014: National Averages and Disparities.
CONCLUSION: This study describes the current status of acute stroke care in Korea. Despite quite acceptable quality of stroke care, it suggests regional and hospital disparities. Expansion of stroke units, stroke center certification or accreditation, and connections between stroke centers and emergency medical services are highly recommended. PMID: 32449325 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Multiple Viewpoints on Physician Home Visits.
Authors: Chung BS PMID: 32449326 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

What Type of Face Mask Is Appropriate for Everyone-Mask-Wearing Policy amidst COVID-19 Pandemic?
Authors: Kim MN PMID: 32449327 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Seventy-two Hours, Targeting Time from First COVID-19 Symptom Onset to Hospitalization.
Authors: Na BJ, Park Y, Huh IS, Kang CR, Lee J, Lee JY PMID: 32449328 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva.
CONCLUSION: SARS-CoV-2 viral load was consistently high in the saliva; it was relatively higher than that in the oropharynx during the early stage of COVID-19. Chlorhexidine mouthwash was effective in reducing the SARS-CoV-2 viral load in the saliva for a short-term period. PMID: 32449329 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 27, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Pregnancy and Epilepsy: a Korean Tertiary Epilepsy Center Review.
CONCLUSION: In WWE, epilepsy classification, number of AEDs taken, and frequency of seizures are not significantly correlated with delivery and fetal condition. This data could be used as a clinical reference for physicians to provide useful information to WWE if they are concerned about their pregnancies. PMID: 32419394 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Development of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of Literature.
Authors: Lee S, Lee HY, Park Y, Ko EJ, Ban TH, Chung BH, Lee HS, Yang CW Abstract Chaga mushrooms are widely used in folk remedies and in alternative medicine. Contrary to many beneficial effects, its adverse effect is rarely reported. We here report a case of end-stage renal disease after long-term taking Chaga mushroom. A 49-year-old Korean man with end stage renal disease (ESRD) was transferred to our hospital. Review of kidney biopsy finding was consistent with chronic tubulointerstitial nephritis with oxalate crystal deposits and drug history revealed long-term exposure to Chaga mushroom powder due to intracta...
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Differential Impact of Serum 25-Hydroxyvitamin D3 Levels on the Prognosis of Patients with Liver Cirrhosis According to MELD and Child-Pugh Scores.
In this study, we investigated the potential role of 25-hydroxyvitamin D3 (25[OH]D3) levels in improving the predictive power of conventional prognostic models for patients with liver cirrhosis. METHODS: We investigated clinical findings, including serum 25(OH)D3 levels at admission, of 155 patients with cirrhosis who were followed up for a median of 16.9 months. RESULTS: Median 25(OH)D3 levels were significantly different among patients exhibiting Child-Pugh grades A, B, and C. Mortality, including urgent transplantation, was significantly associated with 25(OH)D3 levels in univariate analysis. Severe vitamin-D de...
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Vasospasm-related Sudden Cardiac Death Has Outcomes Comparable with Coronary Stenosis in Out-of-Hospital Cardiac Arrest.
Authors: Lee DH, Lee BK, Kim YH, Park YS, Sim MS, Kim SJ, Oh SH, Lee DH, Kim YJ, Kim WY Abstract BACKGROUND: Characteristics of coronary vasospasm-related sudden cardiac death are not well understood. We aimed to compare the characteristics and clinical outcomes between coronary vasospasm and stenosis, in out-of-hospital cardiac arrest (OHCA) survivors, who underwent coronary angiogram (CAG). METHODS: We conducted a multicenter retrospective observational registry-based study at 8 Korean tertiary care centers. Data of OHCA survivors undergoing CAG between 2010 and 2015 were extracted. Patients were divided into...
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Assault-related Factors and Trauma-related Cognitions Associated with Post-traumatic Stress Symptoms in High-distress and Low-distress Korean Female Victims of Sexual Assault.
CONCLUSION: Our results suggest that trauma-related cognitions seem to play an important role in the maintenance of PTSD both of high-distress and low-distress groups, and that effective intervention will need to address these cognitive factors. PMID: 32419398 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Predicting First-Year Growth in Response to Growth Hormone Treatment in Prepubertal Korean Children with Idiopathic Growth Hormone Deficiency: Analysis of Data from the LG Growth Study Database.
Authors: Cho WK, Ahn MB, Kim EY, Cho KS, Jung MH, Suh BK Abstract BACKGROUND: The first-year growth in response to growth hormone (GH) treatment seems to be the most important factor in determining the overall success of GH treatment. METHODS: Data from children (n = 345) who were in the LG Growth Study Database were used to develop a model. All subjects had been diagnosed with idiopathic growth hormone deficiency (GHD) and presented in a prepubertal state during the first year of GH treatment. RESULTS: The Δheight standard deviation score (SDS) during 1st year of GH treatment was correlated positivel...
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Social Distancing against COVID-19: Implication for the Control of Influenza.
Authors: Noh JY, Seong H, Yoon JG, Song JY, Cheong HJ, Kim WJ Abstract Social distancing has been adopted as one of basic protective measures against coronavirus disease 2019 (COVID-19). During 2019-2020 season, influenza epidemic period was exceptionally short and epidemic peak was low in comparison with previous seasons in Korea. Influenza epidemic pattern was bimodal in 2016-2017 and 2018-2019 seasons, however, influenza viruses have rarely been circulating in spring, 2020 in Korea. Although multiple factors could affect the size of influenza epidemic, extensive application of nonpharmaceutical interventions inc...
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Revised Triage and Surveillance Protocols for Temporary Emergency Department Closures in Tertiary Hospitals as a Response to COVID-19 Crisis in Daegu Metropolitan City.
CONCLUSION: Triage screening by emergency physicians and surveillance protocols with an externally located chest imaging facility were effective in the early isolation of COVID-19 patients. In future outbreaks of emerging infectious diseases, efforts should be focused toward the provision of continued ED treatment with the implementation of revised triage and surveillance protocols. PMID: 32419401 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Suggestions to Prepare for the Second Epidemic of COVID-19 in Korea.
Authors: Yum HK PMID: 32419402 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 19, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Disadvantage during Perioperative Period of Total Hip Arthroplasty Using the Direct Anterior Approach: a Network Meta-Analysis.
Authors: Cha Y, Yoo JI, Kim JT, Park CH, Choy W, Ha YC, Koo KH Abstract BACKGROUND: The purpose of this study was to analyze complications of complete hip arthroplasty through systematic review and network meta-analysis of comparative studies of direct anterior approach (DAA), anterolateral approach (LA), and posterolateral approach (PA). METHODS: Prospective randomized controlled trials (RCTs) or quasi-experimental designs evaluating clinical outcomes of DAA, LA, and PA for complete hip arthroplasty are valid if they meet the following criteria: 1) Comparison of clinical outcomes between the three methods for ...
Source: Journal of Korean Medical Science - May 9, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Comparisons of Clinical Outcomes between Weekday-Only and Full-Time, 24-Hour/7-Day Coverage Hospitalist Systems.
CONCLUSION: Uninterrupted weekend coverage hospitalist service is helpful for care-plan decision and timely care transitions for acutely and severely ill patients. PMID: 32383363 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 9, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Age-Period-Cohort Analysis of Influenza in Koreans: the National Health Insurance Research Database, 2009-2018.
CONCLUSION: Since 2014, influenza outbreaks have been increasing every year. The start year of free vaccination decreased the incidence in infants and adults over 65 years of age but the incidence increased from the following year. Because influenza can be primarily prevented by vaccination, reinforcement of vaccination in infants may reduce the disease burden in their parents, and also the risk of infection caused by family transmission. A new vaccination strategy is needed to reduce the incidence and burden of diseases caused by influenza infection. PMID: 32383364 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 9, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Computed Tomography-Based Preoperative Simulation System for Pedicle Screw Fixation in Spinal Surgery.
CONCLUSION: The preoperative planning system allows surgeons and students who are not familiar with pedicle-screw fixation to safely undertake surgery following preoperative planning. It also provides opportunities for screw-fixation training and simulation. PMID: 32383365 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - May 9, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research