A Multicenter Study of Real-world Practice for Management of Abnormal Liver Function Tests in Children with Acute Infectious Diseases
J Korean Med Sci. 2021 Dec 6;36(47):e310. doi: 10.3346/jkms.2021.36.e310.ABSTRACTBACKGROUND: Abnormal liver function tests (LFTs) are commonly seen in pediatric patients with acute infectious diseases. Few studies and no definite clinical guidelines for these conditions are available. The present study aimed to elucidate the causes and factors associated with prolongation of liver enzyme elevation. We also investigated actual real-world practices in Korea.METHODS: A retrospective study was performed on all patients younger than 18 years, who visited six tertiary teaching hospitals around Korea in 2018 for acute infectious ...
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Yoon Lee Dae Yong Yi Yoo Min Lee So Yoon Choi You Jin Choi Kyung Jae Lee Source Type: research

Outcomes after Elective Open Abdominal Aortic Aneurysm Repair in Octogenarians Compared to Younger Patients in Korea
CONCLUSION: Because the mortality rate of octogenarians after elective open AAA repair was not significantly different compared with their younger counterparts, being elderly is not a contraindication for open AAA repair. Low BMI might be associated with increased postoperative mortality.PMID:34873883 | DOI:10.3346/jkms.2021.36.e314 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Joon-Kee Park Jihee Kang Young-Wook Kim Dong-Ik Kim Seon-Hee Heo Eunmi Gil Shin-Young Woo Yang-Jin Park Source Type: research

Growth in Exclusively Breastfed and Non-exclusively Breastfed Children: Comparisons with WHO Child Growth Standards and Korean National Growth Charts
CONCLUSION: In this study using large-scaled national data, Korean breastfed children are shorter and lighter by 3 years 6 months-4 years 6 months, but afterward, there is no significant difference from those who had mixed- or formula-feeding. Substantial disparities in the anthropometric indices of Korean infants under the age of 1 compared to KNCG and WHO-CGS were found, regardless of their infantile feeding types. Our results emphasize the importance of constructing a nationwide reference chart based on actual measurements of BF Korean infants.PMID:34873884 | DOI:10.3346/jkms.2021.36.e315 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Sinyoung Kang Seung Won Lee Hye Ryeong Cha Shin-Hye Kim Man Yong Han Mi Jung Park Source Type: research

Development of the Stress and Anxiety to Viral Epidemics-9 (SAVE-9) Scale for Assessing Work-related Stress and Anxiety in Healthcare Workers in Response to Viral Epidemics
This study developed a new assessment tool, the Stress and Anxiety to Viral Epidemics-9 (SAVE-9) and aimed to validate it among healthcare workers directly affected by COVID-19 in Korea.METHODS: A total of 1,019 healthcare workers responded through anonymous questionnaires during April 20-30, 2020. Exploratory factor analysis (EFA) was conducted to explore the construct validity, and the reliability was assessed using internal consistency measures of Cronbach's alpha coefficients. Receiver operating characteristic analysis was conducted to define the most appropriate cut-off point of SAVE-9 using the Generalized Anxiety Di...
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Seockhoon Chung Hwa Jung Kim Myung Hee Ahn Sungook Yeo Joohee Lee Kyumin Kim Solbi Kang Sooyeon Suh Yong-Wook Shin Source Type: research

Epidemiology of Macrosomia in Korea: Growth and Development
This study aimed to estimate the incidence of macrosomia in Korea and to identify the growth and developmental outcomes and other neonatal complications.METHODS: In total, 397,203 infants who were born in 2013 with birth weight ≥ 2.5 kg and who underwent infant health check-up between their 1st and 7th visit were included from the National Health Insurance Service database. The information was obtained by the International Classification of Diseases-10 codes or self-reported questionnaires in the National Health Screening Program.RESULTS: The distribution of infants by birth weight was as follows: 384,181 (97%) infants ...
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Kee Hyun Cho So Jin Yoon Joohee Lim Hoseon Eun Min Soo Park Kook In Park Heui Seung Jo Soon Min Lee Source Type: research

Emotional Distress of the COVID-19 Cluster Infection on Health Care Workers Working at a National Hospital in Korea
CONCLUSION: Frontline healthcare workers face tremendous psychological burden during the COVID-19 pandemic. Therefore, appropriate psychological interventions should be provided to the HCWs engaged in the management of COVID-19-infected patients.PMID:34873887 | DOI:10.3346/jkms.2021.36.e324 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Og-Jin Jang Young-In Chung Jae-Woon Lee Ho-Chan Kim Jeong Seok Seo Source Type: research

How COVID-19 Affected Healthcare Workers in the Hospital Locked Down due to Early COVID-19 Cases in Korea
J Korean Med Sci. 2021 Dec 6;36(47):e325. doi: 10.3346/jkms.2021.36.e325.ABSTRACTBACKGROUND: The healthcare workers (HCWs) were exposed to never-experienced psychological distress during the early stage of the coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was to investigate how the COVID-19 pandemic affected the mental health of HCWs during the hospital lockdown period due to mass healthcare-associated infection during the early spread of COVID-19.METHODS: A real-time online survey was conducted between April 14-18, 2020 among HCWs who worked at the university hospital where COVID-19 was confirmed in ...
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Hyeon-Ah Lee Myung Hee Ahn Seonjeong Byun Hae-Kook Lee Yong-Sil Kweon Seockhoon Chung Yong-Wook Shin Kyoung-Uk Lee Source Type: research

Drawing Guideline for < em > JKMS < /em > Manuscripts (03): Plots for Categorical Data
J Korean Med Sci. 2021 Dec 6;36(47):e326. doi: 10.3346/jkms.2021.36.e326.ABSTRACTThe appropriate plot effectively conveys the author's conclusions to the readers. JKMS will provide a series of special articles to show you how to make consistent and excellent plots easier. In this article, we will cover plots with categorical data. We will show what 'Bubble Plot,' 'Matrix Bubble Plot,' and 'Matrix Bar Plot' are and how to make them.PMID:34873889 | DOI:10.3346/jkms.2021.36.e326 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - December 7, 2021 Category: Biomedical Science Authors: Jeehyoung Kim Jung Soo Lee San Kim Source Type: research

Prevalence of Bladder Pain Syndrome-like Symptoms: a Population-based Study in Korea
J Korean Med Sci. 2021 Nov 29;36(46):e293. doi: 10.3346/jkms.2021.36.e293.ABSTRACTOBJECTIVES: To investigate the prevalence of bladder pain syndrome (BPS)-like symptoms in the general population of South Korea.METHODS: Between April 16, 2016 and April 29, 2016, we conducted an online survey and computer-assisted personal interviews with adults aged 40-79 years in Korea using structured questionnaires. The sample size was 3,000 (95% confidence level standard error ± 1.79%), and the sampling method was simple randomization according to sex, age, and residential area in proportion to the resident registration demograph...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Jeong Woo Lee Koo Han Yoo Hoon Choi Source Type: research

Underutilisation of Physical Rehabilitation Therapy by Cancer Patients in Korea: a Population-based Study of 958,928 Korean Cancer Patients
CONCLUSION: This claims-based study revealed that rehabilitation therapy for cancer patients is underutilised in Korea. Although patients with metastasis underwent more intensive rehabilitation than patients with early stage cancer, those without brain and bone tumours (the treatment of which is covered by insurance) were less likely to use rehabilitation services. Further efforts to improve the use of rehabilitation would improve the outcomes of cancer patients.PMID:34845872 | PMC:PMC8629717 | DOI:10.3346/jkms.2021.36.e304 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Songhee Cho Seung Hyun Chung Minjoo Kang Aejeong Jo Sung Hoon Sim Yu Jung Kim Eun Joo Yang Source Type: research

Controlling an Outbreak of Multidrug-resistant < em > Acinetobacter baumannii < /em > in a Pediatric Intensive Care Unit: a Retrospective Analysis
We describe the successful management of a MDRAB outbreak by implementing an infection-control strategy in a pediatric intensive care unit (PICU).METHODS: This retrospective study investigated the patients admitted to the PICU in periods 1 (8 months) and 2 (7 months), from the index MDRAB case to intervention implementation, and from intervention implementation to cessation of MDRAB spread. An infection-control strategy was designed following six concepts: 1) cohort isolation of colonized patients, 2) enforcement of hand hygiene, 3) universal contact precautions, 4) environmental management, 5) periodic surveillance cultur...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Joung-Hee Byun Su Eun Park Minhae Seo Jeungmi Jang Mi Sun Hwang Ju Yeoun Song Chulhun L Chang Young A Kim Source Type: research

Clinical Characteristics and Treatment Outcomes of Patients with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection: Experience at a Single Center in Korea
This study aimed to investigate the clinical characteristics and treatment outcomes of patients with HCV/HIV coinfection in Korea.METHODS: We performed a retrospective cohort study of all HCV-monoinfected and HCV/HIV-coinfected patients treated with antivirals at National Medical Center in Seoul, Korea, between January 2009 and March 2020.RESULTS: We enrolled 220 HCV-monoinfected and 23 HCV/HIV-coinfected patients treated with antivirals. The HCV/HIV-coinfected patients were younger (HCV vs. HCV/HIV: 57.3 ± 11.3 vs. 40.7 ± 10.1 years, P
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Dae Hyun Lim Jae Yoon Jeong Seongwoo Nam Jongkyoung Choi Hyeok Choon Kwon Yong Bum Yoon Yeonjae Kim BumSik Chin Source Type: research

Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
J Korean Med Sci. 2021 Nov 29;36(46):e311. doi: 10.3346/jkms.2021.36.e311.ABSTRACTBACKGROUND: ChAdOx1 and BNT162b2 vaccines are currently commonly used against coronavirus disease 2019 worldwide. Our study was designed to determine the serostatus and relative levels of anti-S and neutralizing antibodies in patients who were administered either ChAdOx1 or BNT162b2 vaccine. In addition, we investigated whether the antibody response to each vaccine differed according to sex and age.METHODS: Healthcare workers (HCWs) at a general hospital who were vaccinated with two doses of either ChAdOx1 or BNT162b2 were invited to particip...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Yu Min Kang Dohsik Minn Jaegyun Lim Ki-Deok Lee Dong Ho Jo Kang-Won Choe Moon Jung Kim Jong Min Kim Kwang Nam Kim Source Type: research

Trend of Antibiotic Use in Children with Acute Otitis Media in Korea
In this study, we describe the AOM-related antibiotic use among children in South Korea using national cohort data. We retrieved the Health Insurance Review & Assessment Service data to construct a national cohort of children aged 0-6 years who had been diagnosed with AOM between 2012 and 2018. Of 25,212,264 children included, the antibiotic prescription has increased for amoxicillin/amoxicillin-clavulanate from 56.1% in 2012 to 61.8% in 2018. Prescription has decreased for cephalosporin (35.1% in 2012 to 31.8% in 2018) and macrolide (8.7% in 2012 to 6.4% in 2018). National cohort data have shown an increased trend in ...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Kyu Hyun Park Seung-Ah Choe Ju-Young Shin Young June Choe Source Type: research

Impact of the COVID-19 Pandemic on the Mental Health of Adolescent Students in Daegu, Korea
In this study, we analyzed the stress and emotional crisis experienced by students during the COVID-19 pandemic, its causative factors, and the factors that affect negative emotions.METHODS: We identified the demographic information related to the experiences of unbearable stress and emotional crisis and their causal factors at three points in time: before the pandemic, during its peak, and at the time of the survey (2-3 months after the peak). In addition, we analyzed the factors related to depression and anxiety experienced by students during the COVID-19 pandemic. The Korean version of the Patient Health Questionnaire 9...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Hojun Lee Yeseul Noh Ji Young Seo Sang Hee Park Myoung Haw Kim Seunghee Won Source Type: research

Impact of the Coronavirus Disease Pandemic on Mental Health among Local Residents in Korea: a Cross Sectional Study
CONCLUSION: These results suggest that there is a need for continued interest in the mental health of the general population even after the initial period of coronavirus disease. Additionally, this study may be helpful when considering the resilience or risk factors of mental health in a prolonged disaster situation.PMID:34845878 | PMC:PMC8629714 | DOI:10.3346/jkms.2021.36.e322 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Minsoo Ko Hye-Mi Cho Jinsol Park SuHyuk Chi Changsu Han Hyun-Suk Yi Moon-Soo Lee Source Type: research

Prevalence of Bladder Pain Syndrome-like Symptoms: a Population-based Study in Korea
J Korean Med Sci. 2021 Nov 29;36(46):e293. doi: 10.3346/jkms.2021.36.e293.ABSTRACTOBJECTIVES: To investigate the prevalence of bladder pain syndrome (BPS)-like symptoms in the general population of South Korea.METHODS: Between April 16, 2016 and April 29, 2016, we conducted an online survey and computer-assisted personal interviews with adults aged 40-79 years in Korea using structured questionnaires. The sample size was 3,000 (95% confidence level standard error ± 1.79%), and the sampling method was simple randomization according to sex, age, and residential area in proportion to the resident registration demograph...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Jeong Woo Lee Koo Han Yoo Hoon Choi Source Type: research

Underutilisation of Physical Rehabilitation Therapy by Cancer Patients in Korea: a Population-based Study of 958,928 Korean Cancer Patients
CONCLUSION: This claims-based study revealed that rehabilitation therapy for cancer patients is underutilised in Korea. Although patients with metastasis underwent more intensive rehabilitation than patients with early stage cancer, those without brain and bone tumours (the treatment of which is covered by insurance) were less likely to use rehabilitation services. Further efforts to improve the use of rehabilitation would improve the outcomes of cancer patients.PMID:34845872 | DOI:10.3346/jkms.2021.36.e304 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Songhee Cho Seung Hyun Chung Minjoo Kang Aejeong Jo Sung Hoon Sim Yu Jung Kim Eun Joo Yang Source Type: research

Controlling an Outbreak of Multidrug-resistant < em > Acinetobacter baumannii < /em > in a Pediatric Intensive Care Unit: a Retrospective Analysis
We describe the successful management of a MDRAB outbreak by implementing an infection-control strategy in a pediatric intensive care unit (PICU).METHODS: This retrospective study investigated the patients admitted to the PICU in periods 1 (8 months) and 2 (7 months), from the index MDRAB case to intervention implementation, and from intervention implementation to cessation of MDRAB spread. An infection-control strategy was designed following six concepts: 1) cohort isolation of colonized patients, 2) enforcement of hand hygiene, 3) universal contact precautions, 4) environmental management, 5) periodic surveillance cultur...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Joung-Hee Byun Su Eun Park Minhae Seo Jeungmi Jang Mi Sun Hwang Ju Yeoun Song Chulhun L Chang Young A Kim Source Type: research

Clinical Characteristics and Treatment Outcomes of Patients with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection: Experience at a Single Center in Korea
This study aimed to investigate the clinical characteristics and treatment outcomes of patients with HCV/HIV coinfection in Korea.METHODS: We performed a retrospective cohort study of all HCV-monoinfected and HCV/HIV-coinfected patients treated with antivirals at National Medical Center in Seoul, Korea, between January 2009 and March 2020.RESULTS: We enrolled 220 HCV-monoinfected and 23 HCV/HIV-coinfected patients treated with antivirals. The HCV/HIV-coinfected patients were younger (HCV vs. HCV/HIV: 57.3 ± 11.3 vs. 40.7 ± 10.1 years, P
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Dae Hyun Lim Jae Yoon Jeong Seongwoo Nam Jongkyoung Choi Hyeok Choon Kwon Yong Bum Yoon Yeonjae Kim BumSik Chin Source Type: research

Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
J Korean Med Sci. 2021 Nov 29;36(46):e311. doi: 10.3346/jkms.2021.36.e311.ABSTRACTBACKGROUND: ChAdOx1 and BNT162b2 vaccines are currently commonly used against coronavirus disease 2019 worldwide. Our study was designed to determine the serostatus and relative levels of anti-S and neutralizing antibodies in patients who were administered either ChAdOx1 or BNT162b2 vaccine. In addition, we investigated whether the antibody response to each vaccine differed according to sex and age.METHODS: Healthcare workers (HCWs) at a general hospital who were vaccinated with two doses of either ChAdOx1 or BNT162b2 were invited to particip...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Yu Min Kang Dohsik Minn Jaegyun Lim Ki-Deok Lee Dong Ho Jo Kang-Won Choe Moon Jung Kim Jong Min Kim Kwang Nam Kim Source Type: research

Trend of Antibiotic Use in Children with Acute Otitis Media in Korea
In this study, we describe the AOM-related antibiotic use among children in South Korea using national cohort data. We retrieved the Health Insurance Review & Assessment Service data to construct a national cohort of children aged 0-6 years who had been diagnosed with AOM between 2012 and 2018. Of 25,212,264 children included, the antibiotic prescription has increased for amoxicillin/amoxicillin-clavulanate from 56.1% in 2012 to 61.8% in 2018. Prescription has decreased for cephalosporin (35.1% in 2012 to 31.8% in 2018) and macrolide (8.7% in 2012 to 6.4% in 2018). National cohort data have shown an increased trend in ...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Kyu Hyun Park Seung-Ah Choe Ju-Young Shin Young June Choe Source Type: research

Impact of the COVID-19 Pandemic on the Mental Health of Adolescent Students in Daegu, Korea
In this study, we analyzed the stress and emotional crisis experienced by students during the COVID-19 pandemic, its causative factors, and the factors that affect negative emotions.METHODS: We identified the demographic information related to the experiences of unbearable stress and emotional crisis and their causal factors at three points in time: before the pandemic, during its peak, and at the time of the survey (2-3 months after the peak). In addition, we analyzed the factors related to depression and anxiety experienced by students during the COVID-19 pandemic. The Korean version of the Patient Health Questionnaire 9...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Hojun Lee Yeseul Noh Ji Young Seo Sang Hee Park Myoung Haw Kim Seunghee Won Source Type: research

Impact of the Coronavirus Disease Pandemic on Mental Health among Local Residents in Korea: a Cross Sectional Study
CONCLUSION: These results suggest that there is a need for continued interest in the mental health of the general population even after the initial period of coronavirus disease. Additionally, this study may be helpful when considering the resilience or risk factors of mental health in a prolonged disaster situation.PMID:34845878 | DOI:10.3346/jkms.2021.36.e322 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Minsoo Ko Hye-Mi Cho Jinsol Park SuHyuk Chi Changsu Han Hyun-Suk Yi Moon-Soo Lee Source Type: research

Prevalence of Bladder Pain Syndrome-like Symptoms: a Population-based Study in Korea
J Korean Med Sci. 2021 Nov 29;36(46):e293. doi: 10.3346/jkms.2021.36.e293.ABSTRACTOBJECTIVES: To investigate the prevalence of bladder pain syndrome (BPS)-like symptoms in the general population of South Korea.METHODS: Between April 16, 2016 and April 29, 2016, we conducted an online survey and computer-assisted personal interviews with adults aged 40-79 years in Korea using structured questionnaires. The sample size was 3,000 (95% confidence level standard error ± 1.79%), and the sampling method was simple randomization according to sex, age, and residential area in proportion to the resident registration demograph...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Jeong Woo Lee Koo Han Yoo Hoon Choi Source Type: research

Underutilisation of Physical Rehabilitation Therapy by Cancer Patients in Korea: a Population-based Study of 958,928 Korean Cancer Patients
CONCLUSION: This claims-based study revealed that rehabilitation therapy for cancer patients is underutilised in Korea. Although patients with metastasis underwent more intensive rehabilitation than patients with early stage cancer, those without brain and bone tumours (the treatment of which is covered by insurance) were less likely to use rehabilitation services. Further efforts to improve the use of rehabilitation would improve the outcomes of cancer patients.PMID:34845872 | DOI:10.3346/jkms.2021.36.e304 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Songhee Cho Seung Hyun Chung Minjoo Kang Aejeong Jo Sung Hoon Sim Yu Jung Kim Eun Joo Yang Source Type: research

Controlling an Outbreak of Multidrug-resistant < em > Acinetobacter baumannii < /em > in a Pediatric Intensive Care Unit: a Retrospective Analysis
We describe the successful management of a MDRAB outbreak by implementing an infection-control strategy in a pediatric intensive care unit (PICU).METHODS: This retrospective study investigated the patients admitted to the PICU in periods 1 (8 months) and 2 (7 months), from the index MDRAB case to intervention implementation, and from intervention implementation to cessation of MDRAB spread. An infection-control strategy was designed following six concepts: 1) cohort isolation of colonized patients, 2) enforcement of hand hygiene, 3) universal contact precautions, 4) environmental management, 5) periodic surveillance cultur...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Joung-Hee Byun Su Eun Park Minhae Seo Jeungmi Jang Mi Sun Hwang Ju Yeoun Song Chulhun L Chang Young A Kim Source Type: research

Clinical Characteristics and Treatment Outcomes of Patients with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection: Experience at a Single Center in Korea
This study aimed to investigate the clinical characteristics and treatment outcomes of patients with HCV/HIV coinfection in Korea.METHODS: We performed a retrospective cohort study of all HCV-monoinfected and HCV/HIV-coinfected patients treated with antivirals at National Medical Center in Seoul, Korea, between January 2009 and March 2020.RESULTS: We enrolled 220 HCV-monoinfected and 23 HCV/HIV-coinfected patients treated with antivirals. The HCV/HIV-coinfected patients were younger (HCV vs. HCV/HIV: 57.3 ± 11.3 vs. 40.7 ± 10.1 years, P
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Dae Hyun Lim Jae Yoon Jeong Seongwoo Nam Jongkyoung Choi Hyeok Choon Kwon Yong Bum Yoon Yeonjae Kim BumSik Chin Source Type: research

Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
J Korean Med Sci. 2021 Nov 29;36(46):e311. doi: 10.3346/jkms.2021.36.e311.ABSTRACTBACKGROUND: ChAdOx1 and BNT162b2 vaccines are currently commonly used against coronavirus disease 2019 worldwide. Our study was designed to determine the serostatus and relative levels of anti-S and neutralizing antibodies in patients who were administered either ChAdOx1 or BNT162b2 vaccine. In addition, we investigated whether the antibody response to each vaccine differed according to sex and age.METHODS: Healthcare workers (HCWs) at a general hospital who were vaccinated with two doses of either ChAdOx1 or BNT162b2 were invited to particip...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Yu Min Kang Dohsik Minn Jaegyun Lim Ki-Deok Lee Dong Ho Jo Kang-Won Choe Moon Jung Kim Jong Min Kim Kwang Nam Kim Source Type: research

Trend of Antibiotic Use in Children with Acute Otitis Media in Korea
In this study, we describe the AOM-related antibiotic use among children in South Korea using national cohort data. We retrieved the Health Insurance Review & Assessment Service data to construct a national cohort of children aged 0-6 years who had been diagnosed with AOM between 2012 and 2018. Of 25,212,264 children included, the antibiotic prescription has increased for amoxicillin/amoxicillin-clavulanate from 56.1% in 2012 to 61.8% in 2018. Prescription has decreased for cephalosporin (35.1% in 2012 to 31.8% in 2018) and macrolide (8.7% in 2012 to 6.4% in 2018). National cohort data have shown an increased trend in ...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Kyu Hyun Park Seung-Ah Choe Ju-Young Shin Young June Choe Source Type: research

Impact of the COVID-19 Pandemic on the Mental Health of Adolescent Students in Daegu, Korea
In this study, we analyzed the stress and emotional crisis experienced by students during the COVID-19 pandemic, its causative factors, and the factors that affect negative emotions.METHODS: We identified the demographic information related to the experiences of unbearable stress and emotional crisis and their causal factors at three points in time: before the pandemic, during its peak, and at the time of the survey (2-3 months after the peak). In addition, we analyzed the factors related to depression and anxiety experienced by students during the COVID-19 pandemic. The Korean version of the Patient Health Questionnaire 9...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Hojun Lee Yeseul Noh Ji Young Seo Sang Hee Park Myoung Haw Kim Seunghee Won Source Type: research

Impact of the Coronavirus Disease Pandemic on Mental Health among Local Residents in Korea: a Cross Sectional Study
CONCLUSION: These results suggest that there is a need for continued interest in the mental health of the general population even after the initial period of coronavirus disease. Additionally, this study may be helpful when considering the resilience or risk factors of mental health in a prolonged disaster situation.PMID:34845878 | DOI:10.3346/jkms.2021.36.e322 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Minsoo Ko Hye-Mi Cho Jinsol Park SuHyuk Chi Changsu Han Hyun-Suk Yi Moon-Soo Lee Source Type: research

Prevalence of Bladder Pain Syndrome-like Symptoms: a Population-based Study in Korea
J Korean Med Sci. 2021 Nov 29;36(46):e293. doi: 10.3346/jkms.2021.36.e293.ABSTRACTOBJECTIVES: To investigate the prevalence of bladder pain syndrome (BPS)-like symptoms in the general population of South Korea.METHODS: Between April 16, 2016 and April 29, 2016, we conducted an online survey and computer-assisted personal interviews with adults aged 40-79 years in Korea using structured questionnaires. The sample size was 3,000 (95% confidence level standard error ± 1.79%), and the sampling method was simple randomization according to sex, age, and residential area in proportion to the resident registration demograph...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Jeong Woo Lee Koo Han Yoo Hoon Choi Source Type: research

Underutilisation of Physical Rehabilitation Therapy by Cancer Patients in Korea: a Population-based Study of 958,928 Korean Cancer Patients
CONCLUSION: This claims-based study revealed that rehabilitation therapy for cancer patients is underutilised in Korea. Although patients with metastasis underwent more intensive rehabilitation than patients with early stage cancer, those without brain and bone tumours (the treatment of which is covered by insurance) were less likely to use rehabilitation services. Further efforts to improve the use of rehabilitation would improve the outcomes of cancer patients.PMID:34845872 | DOI:10.3346/jkms.2021.36.e304 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Songhee Cho Seung Hyun Chung Minjoo Kang Aejeong Jo Sung Hoon Sim Yu Jung Kim Eun Joo Yang Source Type: research

Controlling an Outbreak of Multidrug-resistant < em > Acinetobacter baumannii < /em > in a Pediatric Intensive Care Unit: a Retrospective Analysis
We describe the successful management of a MDRAB outbreak by implementing an infection-control strategy in a pediatric intensive care unit (PICU).METHODS: This retrospective study investigated the patients admitted to the PICU in periods 1 (8 months) and 2 (7 months), from the index MDRAB case to intervention implementation, and from intervention implementation to cessation of MDRAB spread. An infection-control strategy was designed following six concepts: 1) cohort isolation of colonized patients, 2) enforcement of hand hygiene, 3) universal contact precautions, 4) environmental management, 5) periodic surveillance cultur...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Joung-Hee Byun Su Eun Park Minhae Seo Jeungmi Jang Mi Sun Hwang Ju Yeoun Song Chulhun L Chang Young A Kim Source Type: research

Clinical Characteristics and Treatment Outcomes of Patients with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection: Experience at a Single Center in Korea
This study aimed to investigate the clinical characteristics and treatment outcomes of patients with HCV/HIV coinfection in Korea.METHODS: We performed a retrospective cohort study of all HCV-monoinfected and HCV/HIV-coinfected patients treated with antivirals at National Medical Center in Seoul, Korea, between January 2009 and March 2020.RESULTS: We enrolled 220 HCV-monoinfected and 23 HCV/HIV-coinfected patients treated with antivirals. The HCV/HIV-coinfected patients were younger (HCV vs. HCV/HIV: 57.3 ± 11.3 vs. 40.7 ± 10.1 years, P
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Dae Hyun Lim Jae Yoon Jeong Seongwoo Nam Jongkyoung Choi Hyeok Choon Kwon Yong Bum Yoon Yeonjae Kim BumSik Chin Source Type: research

Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
J Korean Med Sci. 2021 Nov 29;36(46):e311. doi: 10.3346/jkms.2021.36.e311.ABSTRACTBACKGROUND: ChAdOx1 and BNT162b2 vaccines are currently commonly used against coronavirus disease 2019 worldwide. Our study was designed to determine the serostatus and relative levels of anti-S and neutralizing antibodies in patients who were administered either ChAdOx1 or BNT162b2 vaccine. In addition, we investigated whether the antibody response to each vaccine differed according to sex and age.METHODS: Healthcare workers (HCWs) at a general hospital who were vaccinated with two doses of either ChAdOx1 or BNT162b2 were invited to particip...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Yu Min Kang Dohsik Minn Jaegyun Lim Ki-Deok Lee Dong Ho Jo Kang-Won Choe Moon Jung Kim Jong Min Kim Kwang Nam Kim Source Type: research

Trend of Antibiotic Use in Children with Acute Otitis Media in Korea
In this study, we describe the AOM-related antibiotic use among children in South Korea using national cohort data. We retrieved the Health Insurance Review & Assessment Service data to construct a national cohort of children aged 0-6 years who had been diagnosed with AOM between 2012 and 2018. Of 25,212,264 children included, the antibiotic prescription has increased for amoxicillin/amoxicillin-clavulanate from 56.1% in 2012 to 61.8% in 2018. Prescription has decreased for cephalosporin (35.1% in 2012 to 31.8% in 2018) and macrolide (8.7% in 2012 to 6.4% in 2018). National cohort data have shown an increased trend in ...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Kyu Hyun Park Seung-Ah Choe Ju-Young Shin Young June Choe Source Type: research

Impact of the COVID-19 Pandemic on the Mental Health of Adolescent Students in Daegu, Korea
In this study, we analyzed the stress and emotional crisis experienced by students during the COVID-19 pandemic, its causative factors, and the factors that affect negative emotions.METHODS: We identified the demographic information related to the experiences of unbearable stress and emotional crisis and their causal factors at three points in time: before the pandemic, during its peak, and at the time of the survey (2-3 months after the peak). In addition, we analyzed the factors related to depression and anxiety experienced by students during the COVID-19 pandemic. The Korean version of the Patient Health Questionnaire 9...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Hojun Lee Yeseul Noh Ji Young Seo Sang Hee Park Myoung Haw Kim Seunghee Won Source Type: research

Impact of the Coronavirus Disease Pandemic on Mental Health among Local Residents in Korea: a Cross Sectional Study
CONCLUSION: These results suggest that there is a need for continued interest in the mental health of the general population even after the initial period of coronavirus disease. Additionally, this study may be helpful when considering the resilience or risk factors of mental health in a prolonged disaster situation.PMID:34845878 | DOI:10.3346/jkms.2021.36.e322 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Minsoo Ko Hye-Mi Cho Jinsol Park SuHyuk Chi Changsu Han Hyun-Suk Yi Moon-Soo Lee Source Type: research

Prevalence of Bladder Pain Syndrome-like Symptoms: a Population-based Study in Korea
J Korean Med Sci. 2021 Nov 29;36(46):e293. doi: 10.3346/jkms.2021.36.e293.ABSTRACTOBJECTIVES: To investigate the prevalence of bladder pain syndrome (BPS)-like symptoms in the general population of South Korea.METHODS: Between April 16, 2016 and April 29, 2016, we conducted an online survey and computer-assisted personal interviews with adults aged 40-79 years in Korea using structured questionnaires. The sample size was 3,000 (95% confidence level standard error ± 1.79%), and the sampling method was simple randomization according to sex, age, and residential area in proportion to the resident registration demograph...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Jeong Woo Lee Koo Han Yoo Hoon Choi Source Type: research

Underutilisation of Physical Rehabilitation Therapy by Cancer Patients in Korea: a Population-based Study of 958,928 Korean Cancer Patients
CONCLUSION: This claims-based study revealed that rehabilitation therapy for cancer patients is underutilised in Korea. Although patients with metastasis underwent more intensive rehabilitation than patients with early stage cancer, those without brain and bone tumours (the treatment of which is covered by insurance) were less likely to use rehabilitation services. Further efforts to improve the use of rehabilitation would improve the outcomes of cancer patients.PMID:34845872 | DOI:10.3346/jkms.2021.36.e304 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Songhee Cho Seung Hyun Chung Minjoo Kang Aejeong Jo Sung Hoon Sim Yu Jung Kim Eun Joo Yang Source Type: research

Controlling an Outbreak of Multidrug-resistant < em > Acinetobacter baumannii < /em > in a Pediatric Intensive Care Unit: a Retrospective Analysis
We describe the successful management of a MDRAB outbreak by implementing an infection-control strategy in a pediatric intensive care unit (PICU).METHODS: This retrospective study investigated the patients admitted to the PICU in periods 1 (8 months) and 2 (7 months), from the index MDRAB case to intervention implementation, and from intervention implementation to cessation of MDRAB spread. An infection-control strategy was designed following six concepts: 1) cohort isolation of colonized patients, 2) enforcement of hand hygiene, 3) universal contact precautions, 4) environmental management, 5) periodic surveillance cultur...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Joung-Hee Byun Su Eun Park Minhae Seo Jeungmi Jang Mi Sun Hwang Ju Yeoun Song Chulhun L Chang Young A Kim Source Type: research

Clinical Characteristics and Treatment Outcomes of Patients with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection: Experience at a Single Center in Korea
This study aimed to investigate the clinical characteristics and treatment outcomes of patients with HCV/HIV coinfection in Korea.METHODS: We performed a retrospective cohort study of all HCV-monoinfected and HCV/HIV-coinfected patients treated with antivirals at National Medical Center in Seoul, Korea, between January 2009 and March 2020.RESULTS: We enrolled 220 HCV-monoinfected and 23 HCV/HIV-coinfected patients treated with antivirals. The HCV/HIV-coinfected patients were younger (HCV vs. HCV/HIV: 57.3 ± 11.3 vs. 40.7 ± 10.1 years, P
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Dae Hyun Lim Jae Yoon Jeong Seongwoo Nam Jongkyoung Choi Hyeok Choon Kwon Yong Bum Yoon Yeonjae Kim BumSik Chin Source Type: research

Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
J Korean Med Sci. 2021 Nov 29;36(46):e311. doi: 10.3346/jkms.2021.36.e311.ABSTRACTBACKGROUND: ChAdOx1 and BNT162b2 vaccines are currently commonly used against coronavirus disease 2019 worldwide. Our study was designed to determine the serostatus and relative levels of anti-S and neutralizing antibodies in patients who were administered either ChAdOx1 or BNT162b2 vaccine. In addition, we investigated whether the antibody response to each vaccine differed according to sex and age.METHODS: Healthcare workers (HCWs) at a general hospital who were vaccinated with two doses of either ChAdOx1 or BNT162b2 were invited to particip...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Yu Min Kang Dohsik Minn Jaegyun Lim Ki-Deok Lee Dong Ho Jo Kang-Won Choe Moon Jung Kim Jong Min Kim Kwang Nam Kim Source Type: research

Trend of Antibiotic Use in Children with Acute Otitis Media in Korea
In this study, we describe the AOM-related antibiotic use among children in South Korea using national cohort data. We retrieved the Health Insurance Review & Assessment Service data to construct a national cohort of children aged 0-6 years who had been diagnosed with AOM between 2012 and 2018. Of 25,212,264 children included, the antibiotic prescription has increased for amoxicillin/amoxicillin-clavulanate from 56.1% in 2012 to 61.8% in 2018. Prescription has decreased for cephalosporin (35.1% in 2012 to 31.8% in 2018) and macrolide (8.7% in 2012 to 6.4% in 2018). National cohort data have shown an increased trend in ...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Kyu Hyun Park Seung-Ah Choe Ju-Young Shin Young June Choe Source Type: research

Impact of the COVID-19 Pandemic on the Mental Health of Adolescent Students in Daegu, Korea
In this study, we analyzed the stress and emotional crisis experienced by students during the COVID-19 pandemic, its causative factors, and the factors that affect negative emotions.METHODS: We identified the demographic information related to the experiences of unbearable stress and emotional crisis and their causal factors at three points in time: before the pandemic, during its peak, and at the time of the survey (2-3 months after the peak). In addition, we analyzed the factors related to depression and anxiety experienced by students during the COVID-19 pandemic. The Korean version of the Patient Health Questionnaire 9...
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Hojun Lee Yeseul Noh Ji Young Seo Sang Hee Park Myoung Haw Kim Seunghee Won Source Type: research

Impact of the Coronavirus Disease Pandemic on Mental Health among Local Residents in Korea: a Cross Sectional Study
CONCLUSION: These results suggest that there is a need for continued interest in the mental health of the general population even after the initial period of coronavirus disease. Additionally, this study may be helpful when considering the resilience or risk factors of mental health in a prolonged disaster situation.PMID:34845878 | DOI:10.3346/jkms.2021.36.e322 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 30, 2021 Category: Biomedical Science Authors: Minsoo Ko Hye-Mi Cho Jinsol Park SuHyuk Chi Changsu Han Hyun-Suk Yi Moon-Soo Lee Source Type: research

Analysis of Tertiary Hospital Utilization in Pediatric Orthopaedics: a Study Using Nationwide Sample Data from Korea
CONCLUSION: The admission rates of frequent POS diagnoses in tertiary hospitals are high. Considering that these rates are the most important factors for the classification of disease severity, POS diseases seem to be underestimated in terms of severity. This may lead to a tendency for tertiary hospitals to intentionally reduce the admission of children with POS diseases. As a result, these children may not receive appropriate professional care. Therefore, for the disease severity, POS diseases should be classified differently from general AOS diseases by using different criteria reflecting the patient's age.PMID:34811973 ...
Source: Journal of Korean Medical Science - November 23, 2021 Category: Biomedical Science Authors: Kunhyung Bae Soo-Sung Park Jinhee Park Michael Seungcheol Kang Source Type: research

Arthroscopic Partial Meniscectomy versus Physical Therapy for Degenerative Meniscal Tear: a Systematic Review
CONCLUSIONS: Our study showed that knee pain was significantly improved in the APM group compared to non-operative care group at 6 months and over 24 months. Our result was based on only 3 randomized controlled trials (RCTs) revealing a significant knowledge gap, hence demanding more high-quality RCTs in OA patients.TRIAL REGISTRATION: PROSPERO Identifier: CRD42020215965.PMID:34811974 | DOI:10.3346/jkms.2021.36.e292 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 23, 2021 Category: Biomedical Science Authors: Miyoung Choi Su Jung Lee Chan Mi Park Seungeun Ryoo Sunghyun Kim Ju Yeon Jang Hyun Ah Kim Source Type: research