Pre-Sepsis Length of Hospital Stay and Mortality: A Nationwide Multicenter Cohort Study
CONCLUSION: Extended LOS before developing sepsis is associated with higher in-hospital mortality. More careful management is required when sepsis occurs in patients hospitalized for ≥ 5 days.PMID:38469963 | DOI:10.3346/jkms.2024.39.e87 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 12, 2024 Category: Biomedical Science Authors: Joong-Yub Kim Hong Yeul Lee Jinwoo Lee Dong Kyu Oh Su Yeon Lee Mi Hyeon Park Chae-Man Lim Sang-Min Lee Korean Sepsis Alliance (KSA) Investigators Source Type: research
Risk of Cerebral Aneurysm Rupture After Liver Transplantation: Development and Validation of a Hemorrhagic Stroke Scoring Model
CONCLUSION: The incidence of UIA and SAH was very low in LT patients. A poor admission mental status, diagnosis of UIA, serum ammonia levels, and MELD scores were significantly associated with the risk of HS within one year after LT. Our scoring system showed a good discrimination to predict the HS in LT patients.PMID:38469964 | DOI:10.3346/jkms.2024.39.e88 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 12, 2024 Category: Biomedical Science Authors: Minwoo Kim Jae Hyun Kim Wonhyoung Park Jung Cheol Park Jae Sung Ahn Byung Duk Kwun Sung-Gyu Lee Shin Hwang Moinay Kim Seungjoo Lee Source Type: research
Dark Data in Real-World Evidence: Challenges, Implications, and the Imperative of Data Literacy in Medical Research
In this study, we explore the impact of extrinsic factors on RWE outcomes, focusing on "dark data," which refers to data collected but not used or excluded from the analyses. Dark data can arise in many ways during research process, from selecting study samples to data collection and analysis. However, even unused or unanalyzed dark data hold potential insights, providing a comprehensive view of clinical contexts. Extrinsic factors lead to divergent RWE outcomes that could differ from RCTs beyond statistical correction's scope. Two main types of dark data exist: "known-unknown" and "unknown-unknown." The distinction betwee...
Source: Journal of Korean Medical Science - March 12, 2024 Category: Biomedical Science Authors: Hun-Sung Kim Source Type: research
Modest Effects of Neurofeedback-Assisted Meditation Using a Wearable Device on Stress Reduction: A Randomized, Double-Blind, and Controlled Study
CONCLUSION: Neurofeedback-assisted meditation using a wearable device can help improve subjective stress reduction compared with non-assisted meditation. These results support neurofeedback as an effective adjunct to meditation for relieving stress.TRIAL REGISTRATION: Clinical Research Information Service Identifier: KCT0007413.PMID:38469966 | DOI:10.3346/jkms.2024.39.e94 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 12, 2024 Category: Biomedical Science Authors: Eunyoung Lee Jung Kyung Hong Hayun Choi In-Young Yoon Source Type: research
Trends in Incidence and Drug Prescriptions for Croup in Children Under 5 Years of Age: A 2002-2019 Population-Based Study
CONCLUSION: Over the past two decades, croup incidence has risen, accompanied by increased epinephrine use and decreased antibiotic prescriptions. Longer hospitalization and higher medication use were mainly observed in primary care facilities.PMID:38469967 | DOI:10.3346/jkms.2024.39.e95 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 12, 2024 Category: Biomedical Science Authors: Bo Hee Kim Eun Kyo Ha Hana Yoo Soonchul Lee Yeong Ho Rha Man Yong Han Ju Hee Kim Source Type: research
In This Issue on 11-March-2024
J Korean Med Sci. 2024 Mar 11;39(9):e99. doi: 10.3346/jkms.2024.39.e99.NO ABSTRACTPMID:38469968 | DOI:10.3346/jkms.2024.39.e99 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 12, 2024 Category: Biomedical Science Authors: Jin-Hong Yoo Source Type: research
Encouraging Message From the Korean Academy of Medical Sciences to Junior Doctors in Struggle
J Korean Med Sci. 2024 Mar 11;39(9):e108. doi: 10.3346/jkms.2024.39.e108.NO ABSTRACTPMID:38469969 | DOI:10.3346/jkms.2024.39.e108 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 12, 2024 Category: Biomedical Science Authors: Hyoung Wook Park Source Type: research
Chromosomal Microarray Analysis in Fetuses With Ultrasonographic Soft Markers: A Meta-Analysis of the Current Evidence
CONCLUSION: CMA could aid in risk assessment and pregnancy counseling in pregnancies where the fetus has isolated ultrasonographic soft markers along with a normal karyotype.PMID:38442716 | PMC:PMC10911939 | DOI:10.3346/jkms.2024.39.e70 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Uisuk Kim Young Mi Jung Sohee Oh Ji Hye Bae Jeesun Lee Chan-Wook Park Joong Shin Park Jong Kwan Jun Seung Mi Lee Source Type: research
Comparison of High- and Low-Dose Rivaroxaban Regimens in Elderly East Asian Patients With Atrial Fibrillation
CONCLUSION: This study revealed the safety and effectiveness of either dose regimen of rivaroxaban in an Asian population for stroke prevention of AF. Considerable numbers of patients are receiving LDRR therapy in real-world practice in Asia. Both regimens were safe and effective for these patients.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04096547.PMID:38442717 | PMC:PMC10911935 | DOI:10.3346/jkms.2024.39.e72 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Ju Youn Kim Juwon Kim Seung-Jung Park Kyoung-Min Park June Soo Kim Sung-Hwan Kim Jaemin Shim Eue Keun Choi Dae-Hyeok Kim Il-Young Oh Young Keun On XAIENT Study Group Source Type: research
Risk Factors for the Mortality of Patients With Coronavirus Disease 2019 Requiring Extracorporeal Membrane Oxygenation in a Non-Centralized Setting: A Nationwide Study
CONCLUSION: Older age and receipt of CRRT were associated with higher mortality rates among patients with COVID-19 who received ECMO.PMID:38442718 | PMC:PMC10911941 | DOI:10.3346/jkms.2024.39.e75 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Tae Wan Kim Won-Young Kim Sunghoon Park Su Hwan Lee Onyu Park Taehwa Kim Hye Ju Yeo Jin Ho Jang Woo Hyun Cho Jin-Won Huh Sang-Min Lee Chi Ryang Chung Jongmin Lee Jung Soo Kim Sung Yoon Lim Ae-Rin Baek Jung-Wan Yoo Ho Cheol Kim Eun Young Choi Chul Park Tae Source Type: research
Adverse Events Following COVID-19 Vaccination in Adolescents: Insights From Pharmacovigilance Study of VigiBase
CONCLUSION: In this study, there were disproportionate reporting of immune-related AEs following COVID-19 vaccination. While awaiting definitive evidence, there is a need to closely monitor for any signs of immune-related AEs following COVID-19 vaccination among adolescents.PMID:38442719 | PMC:PMC10911943 | DOI:10.3346/jkms.2024.39.e76 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Dong Hyuk Kim Ju Hwan Kim In-Sun Oh Young June Choe Seung-Ah Choe Ju-Young Shin Source Type: research
Association Between Multiple Heavy Metal Exposures and Cholesterol Levels in Residents Living Near a Smelter Plant in Korea
CONCLUSION: These results suggest that the cholesterol levels of residents around the Janghang refinery plant may be elevated owing to exposure to multiple heavy metals.PMID:38442720 | PMC:PMC10911942 | DOI:10.3346/jkms.2024.39.e77 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Sun-In Moon Dong-Hyuk Yim Kyunghi Choi Sang-Yong Eom Byung-Sun Choi Jung-Duck Park Heon Kim Yong-Dae Kim Source Type: research
Mildly Reduced Renal Function Is Associated With Increased Heart Failure Admissions in Patients With Hypertrophic Cardiomyopathy
CONCLUSION: This real-world observation showed that even mildly reduced renal function (i.e., eGFR 60-89 mL/min/1.73 m²) in patients with HCM was associated with an increased risk of MACEs, especially for HHF.PMID:38442721 | PMC:PMC10911940 | DOI:10.3346/jkms.2024.39.e80 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Nan Young Bae Tae-Min Rhee Chan Soon Park You-Jung Choi Hyun-Jung Lee Hong-Mi Choi Jun-Bean Park Yeonyee E Yoon Yong-Jin Kim Goo-Yeong Cho In-Chang Hwang Hyung-Kwan Kim Source Type: research
Impact of Lactate Dehydrogenase and Hemoglobin Levels on Clinical Outcomes in Patients With Paroxysmal Nocturnal Hemoglobinuria: Results From the National Korean PNH Registry
CONCLUSION: In complement inhibitor-naïve patients with PNH, LDH ≥ 1.5 × ULN was a significant predictor of TE, and TE was a significant predictor of death. Hb was not a significant predictor of TE, impaired renal function, or death. Therefore, controlling IVH will improve clinical outcomes for patients with PNH.PMID:38442722 | PMC:PMC10911938 | DOI:10.3346/jkms.2024.39.e81 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Jun Ho Jang Jin Seok Kim Cindy Thiow Koon Lim Nora J Kleinman Karl-Johan Myren Alice Wang Yogesh Patel Jong Wook Lee Source Type: research
Surveillance Systems for Assessing Vaccine Safety: Possibilities and Limitations
J Korean Med Sci. 2024 Mar 4;39(8):e90. doi: 10.3346/jkms.2024.39.e90.NO ABSTRACTPMID:38442723 | PMC:PMC10911944 | DOI:10.3346/jkms.2024.39.e90 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Joon Kee Lee Source Type: research
