Adverse Reactions After Intradermal Vaccination With JYNNEOS for Mpox in Korea
J Korean Med Sci. 2024 Mar 4;39(8):e100. doi: 10.3346/jkms.2024.39.e100.ABSTRACTIn response to the Mpox domestic epidemic, South Korea initiated a nationwide vaccination program in May 2023, administering a 0.1 mL intradermal dose of JYNNEOS (Modified Vaccinia Ankara vaccine, Bavarian Nordic) to a high-risk group. To investigate the adverse reactions after intradermal JYNNEOS vaccination, an anonymous online survey was conducted at the National Medical Center from May 22 to July 31, 2023. Overall, 142 individuals responded. Over 80% of the respondents reported local reactions of predominantly mild severity. The predominant...
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: So Yun Lim Yu Mi Jung Yeonjae Kim Gayeon Kim Jaehyun Jeon BumSik Chin Min-Kyung Kim Source Type: research

Chromosomal Microarray Analysis in Fetuses With Ultrasonographic Soft Markers: A Meta-Analysis of the Current Evidence
CONCLUSION: CMA could aid in risk assessment and pregnancy counseling in pregnancies where the fetus has isolated ultrasonographic soft markers along with a normal karyotype.PMID:38442716 | PMC:PMC10911939 | DOI:10.3346/jkms.2024.39.e70 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Uisuk Kim Young Mi Jung Sohee Oh Ji Hye Bae Jeesun Lee Chan-Wook Park Joong Shin Park Jong Kwan Jun Seung Mi Lee Source Type: research

Comparison of High- and Low-Dose Rivaroxaban Regimens in Elderly East Asian Patients With Atrial Fibrillation
CONCLUSION: This study revealed the safety and effectiveness of either dose regimen of rivaroxaban in an Asian population for stroke prevention of AF. Considerable numbers of patients are receiving LDRR therapy in real-world practice in Asia. Both regimens were safe and effective for these patients.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04096547.PMID:38442717 | PMC:PMC10911935 | DOI:10.3346/jkms.2024.39.e72 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Ju Youn Kim Juwon Kim Seung-Jung Park Kyoung-Min Park June Soo Kim Sung-Hwan Kim Jaemin Shim Eue Keun Choi Dae-Hyeok Kim Il-Young Oh Young Keun On XAIENT Study Group Source Type: research

Risk Factors for the Mortality of Patients With Coronavirus Disease 2019 Requiring Extracorporeal Membrane Oxygenation in a Non-Centralized Setting: A Nationwide Study
CONCLUSION: Older age and receipt of CRRT were associated with higher mortality rates among patients with COVID-19 who received ECMO.PMID:38442718 | PMC:PMC10911941 | DOI:10.3346/jkms.2024.39.e75 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Tae Wan Kim Won-Young Kim Sunghoon Park Su Hwan Lee Onyu Park Taehwa Kim Hye Ju Yeo Jin Ho Jang Woo Hyun Cho Jin-Won Huh Sang-Min Lee Chi Ryang Chung Jongmin Lee Jung Soo Kim Sung Yoon Lim Ae-Rin Baek Jung-Wan Yoo Ho Cheol Kim Eun Young Choi Chul Park Tae Source Type: research

Adverse Events Following COVID-19 Vaccination in Adolescents: Insights From Pharmacovigilance Study of VigiBase
CONCLUSION: In this study, there were disproportionate reporting of immune-related AEs following COVID-19 vaccination. While awaiting definitive evidence, there is a need to closely monitor for any signs of immune-related AEs following COVID-19 vaccination among adolescents.PMID:38442719 | PMC:PMC10911943 | DOI:10.3346/jkms.2024.39.e76 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Dong Hyuk Kim Ju Hwan Kim In-Sun Oh Young June Choe Seung-Ah Choe Ju-Young Shin Source Type: research

Association Between Multiple Heavy Metal Exposures and Cholesterol Levels in Residents Living Near a Smelter Plant in Korea
CONCLUSION: These results suggest that the cholesterol levels of residents around the Janghang refinery plant may be elevated owing to exposure to multiple heavy metals.PMID:38442720 | PMC:PMC10911942 | DOI:10.3346/jkms.2024.39.e77 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Sun-In Moon Dong-Hyuk Yim Kyunghi Choi Sang-Yong Eom Byung-Sun Choi Jung-Duck Park Heon Kim Yong-Dae Kim Source Type: research

Mildly Reduced Renal Function Is Associated With Increased Heart Failure Admissions in Patients With Hypertrophic Cardiomyopathy
CONCLUSION: This real-world observation showed that even mildly reduced renal function (i.e., eGFR 60-89 mL/min/1.73 m²) in patients with HCM was associated with an increased risk of MACEs, especially for HHF.PMID:38442721 | PMC:PMC10911940 | DOI:10.3346/jkms.2024.39.e80 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Nan Young Bae Tae-Min Rhee Chan Soon Park You-Jung Choi Hyun-Jung Lee Hong-Mi Choi Jun-Bean Park Yeonyee E Yoon Yong-Jin Kim Goo-Yeong Cho In-Chang Hwang Hyung-Kwan Kim Source Type: research

Impact of Lactate Dehydrogenase and Hemoglobin Levels on Clinical Outcomes in Patients With Paroxysmal Nocturnal Hemoglobinuria: Results From the National Korean PNH Registry
CONCLUSION: In complement inhibitor-naïve patients with PNH, LDH ≥ 1.5 × ULN was a significant predictor of TE, and TE was a significant predictor of death. Hb was not a significant predictor of TE, impaired renal function, or death. Therefore, controlling IVH will improve clinical outcomes for patients with PNH.PMID:38442722 | PMC:PMC10911938 | DOI:10.3346/jkms.2024.39.e81 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Jun Ho Jang Jin Seok Kim Cindy Thiow Koon Lim Nora J Kleinman Karl-Johan Myren Alice Wang Yogesh Patel Jong Wook Lee Source Type: research

Surveillance Systems for Assessing Vaccine Safety: Possibilities and Limitations
J Korean Med Sci. 2024 Mar 4;39(8):e90. doi: 10.3346/jkms.2024.39.e90.NO ABSTRACTPMID:38442723 | PMC:PMC10911944 | DOI:10.3346/jkms.2024.39.e90 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Joon Kee Lee Source Type: research

In This Issue on 04-March-2024
J Korean Med Sci. 2024 Mar 4;39(8):e91. doi: 10.3346/jkms.2024.39.e91.NO ABSTRACTPMID:38442724 | PMC:PMC10911937 | DOI:10.3346/jkms.2024.39.e91 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Jin-Hong Yoo Source Type: research

Adverse Reactions After Intradermal Vaccination With JYNNEOS for Mpox in Korea
J Korean Med Sci. 2024 Mar 4;39(8):e100. doi: 10.3346/jkms.2024.39.e100.ABSTRACTIn response to the Mpox domestic epidemic, South Korea initiated a nationwide vaccination program in May 2023, administering a 0.1 mL intradermal dose of JYNNEOS (Modified Vaccinia Ankara vaccine, Bavarian Nordic) to a high-risk group. To investigate the adverse reactions after intradermal JYNNEOS vaccination, an anonymous online survey was conducted at the National Medical Center from May 22 to July 31, 2023. Overall, 142 individuals responded. Over 80% of the respondents reported local reactions of predominantly mild severity. The predominant...
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: So Yun Lim Yu Mi Jung Yeonjae Kim Gayeon Kim Jaehyun Jeon BumSik Chin Min-Kyung Kim Source Type: research

Chromosomal Microarray Analysis in Fetuses With Ultrasonographic Soft Markers: A Meta-Analysis of the Current Evidence
CONCLUSION: CMA could aid in risk assessment and pregnancy counseling in pregnancies where the fetus has isolated ultrasonographic soft markers along with a normal karyotype.PMID:38442716 | PMC:PMC10911939 | DOI:10.3346/jkms.2024.39.e70 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Uisuk Kim Young Mi Jung Sohee Oh Ji Hye Bae Jeesun Lee Chan-Wook Park Joong Shin Park Jong Kwan Jun Seung Mi Lee Source Type: research

Comparison of High- and Low-Dose Rivaroxaban Regimens in Elderly East Asian Patients With Atrial Fibrillation
CONCLUSION: This study revealed the safety and effectiveness of either dose regimen of rivaroxaban in an Asian population for stroke prevention of AF. Considerable numbers of patients are receiving LDRR therapy in real-world practice in Asia. Both regimens were safe and effective for these patients.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04096547.PMID:38442717 | PMC:PMC10911935 | DOI:10.3346/jkms.2024.39.e72 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Ju Youn Kim Juwon Kim Seung-Jung Park Kyoung-Min Park June Soo Kim Sung-Hwan Kim Jaemin Shim Eue Keun Choi Dae-Hyeok Kim Il-Young Oh Young Keun On XAIENT Study Group Source Type: research

Risk Factors for the Mortality of Patients With Coronavirus Disease 2019 Requiring Extracorporeal Membrane Oxygenation in a Non-Centralized Setting: A Nationwide Study
CONCLUSION: Older age and receipt of CRRT were associated with higher mortality rates among patients with COVID-19 who received ECMO.PMID:38442718 | PMC:PMC10911941 | DOI:10.3346/jkms.2024.39.e75 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Tae Wan Kim Won-Young Kim Sunghoon Park Su Hwan Lee Onyu Park Taehwa Kim Hye Ju Yeo Jin Ho Jang Woo Hyun Cho Jin-Won Huh Sang-Min Lee Chi Ryang Chung Jongmin Lee Jung Soo Kim Sung Yoon Lim Ae-Rin Baek Jung-Wan Yoo Ho Cheol Kim Eun Young Choi Chul Park Tae Source Type: research

Adverse Events Following COVID-19 Vaccination in Adolescents: Insights From Pharmacovigilance Study of VigiBase
CONCLUSION: In this study, there were disproportionate reporting of immune-related AEs following COVID-19 vaccination. While awaiting definitive evidence, there is a need to closely monitor for any signs of immune-related AEs following COVID-19 vaccination among adolescents.PMID:38442719 | PMC:PMC10911943 | DOI:10.3346/jkms.2024.39.e76 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 5, 2024 Category: Biomedical Science Authors: Dong Hyuk Kim Ju Hwan Kim In-Sun Oh Young June Choe Seung-Ah Choe Ju-Young Shin Source Type: research