Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells
CONCLUSIONS: In summary, vaspin observably reduces HG-mediated inhibition of PDLSCs OD by modulating the TGF-β1/Smad signaling pathway. Vaspin may be a potential therapeutic for periodontal tissue regeneration in diabetic patients.PMID:38699861 | DOI:10.1111/jre.13254 (Source: Cell Research)
Source: Cell Research - May 3, 2024 Category: Cytology Authors: Zhihui Jing Xinran Feng Xin Li Xiaoyu Zhang Chunling Pan Source Type: research
< em > Bletilla striata < /em > Polysaccharide-/Chitosan-Based Self-Healing Hydrogel with Enhanced Photothermal Effect for Rapid Healing of Diabetic Infected Wounds via the Regulation of Microenvironment
Biomacromolecules. 2024 May 3. doi: 10.1021/acs.biomac.4c00013. Online ahead of print.ABSTRACTThe management of diabetic ulcers poses a significant challenge worldwide, and persistent hyperglycemia makes patients susceptible to bacterial infections. Unfortunately, the overuse of antibiotics may lead to drug resistance and prolonged infections, contributing to chronic inflammation and hindering the healing process. To address these issues, a photothermal therapy technique was incorporated in the preparation of wound dressings. This innovative solution involved the formulation of a self-healing and injectable hydrogel matrix...
Source: Biomacromolecules - May 3, 2024 Category: Biochemistry Authors: Kai Zhao Zhengbo Hu Xingcan Chen Yuchi Chen Mingyuan Zhou Xiaoqing Ye Fangmei Zhou Bingqi Zhu Zhishan Ding Source Type: research
Common Comorbidities in Patients with Remitting Seronegative and Symmetrical Synovitis with Pitting Edema (RS3PE)
CONCLUSIONS: We believe that future case studies on RS3PE should include an assessment of various comorbidities that can be seen in patients with this autoinflammatory disorder. The increased availability of musculoskeletal ultrasound provides a potential area of study to differentiate this disorder from other inflammatory arthritis and improve reaching the correct diagnosis.PMID:38701844 | DOI:10.14423/SMJ.0000000000001679 (Source: Southern Medical Journal)
Source: Southern Medical Journal - May 3, 2024 Category: General Medicine Authors: Elmira Esmaeilzadeh Christopher R Morris Source Type: research
Corrigendum to A Real-World Precision Medicine Program Including the KidneyIntelX Test Effectively Changes Management Decisions and Outcomes for Patients With Early-Stage Diabetic Kidney Disease
J Prim Care Community Health. 2024 Jan-Dec;15:21501319241253928. doi: 10.1177/21501319241253928.NO ABSTRACTPMID:38700044 | DOI:10.1177/21501319241253928 (Source: Primary Care)
Source: Primary Care - May 3, 2024 Category: Primary Care Source Type: research
Supporting best practice in the management of chronic diseases in primary health care settings: a scoping review of training programs for Indigenous Health Workers and Practitioners
Conclusions Multifaceted training programs for Aboriginal health workers are well received and may improve workforce capability.PMID:38701239 | DOI:10.1071/PY23124 (Source: Primary Care)
Source: Primary Care - May 3, 2024 Category: Primary Care Authors: Odette Pearson Shwikar Othman Kate Colmer Sana Ishaque Gloria Mejia Sarah Crossing David Jesudason Gary Wittert Paul Zimmet Sophia Zoungas Natalie Wischer Kim Morey Jane Giles Sara Jones Alex Brown Saravana Kumar Source Type: research
Pets, obesity and nurses: surgical site infections in the community
Br J Community Nurs. 2024 May 2;29(5):248-250. doi: 10.12968/bjcn.2024.29.5.248.ABSTRACTMany surgical site infections (SSI) emerge after the patient is discharged from hospital. So, practice and district nurses should remain alert for SSIs and address modifiable risk factors, which include helping obese patients lose weight, optimising glucose control in people with diabetes and encouraging smoking cessation. Animals, including pets, are important reservoirs of resistant bacteria. By optimising SSI care, nurses can not only improve wound healing but also help preserve antibiotic efficacy.PMID:38701010 | DOI:10.12968/bjcn.2...
Source: British Journal of Community Nursing - May 3, 2024 Category: Nursing Authors: Mark Greener Source Type: research
Delegation of insulin administration: a survey of community nursing teams in England
Br J Community Nurs. 2024 May 2;29(5):238-244. doi: 10.12968/bjcn.2024.29.5.238.ABSTRACTIn community nursing, the administration of insulin for people with type 2 diabetes can be delegated by registered nurses to healthcare support workers. Although a voluntary framework in England provides national guidance, little is known about its uptake. The project aim was to determine the roll-out, characteristics and support needs in relation to the delegation of insulin administration in community settings. An online survey was disseminated to community nursing services in England via social media and nursing networks. Of the 115 ...
Source: British Journal of Community Nursing - May 3, 2024 Category: Nursing Authors: Karen Stenner Judith Edwards Lesley Mills Sam Sherrington Freda Mold Source Type: research
Diabetic bladder dysfunction
This article uses a case history approach to examine how diabetes can affect the bladder.PMID:38701015 | DOI:10.12968/bjcn.2024.29.5.232 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - May 3, 2024 Category: Nursing Authors: Linda Nazarko Source Type: research
Pediatric hypertension as an early manifestation of cardiovascular disease in children
J Bras Nefrol. 2024 May 3;46(4):e20230159. doi: 10.1590/2175-8239-JBN-2023-0159en. eCollection 2024.ABSTRACTIn adults, cardiovascular events associated with arterial hypertension (AH) have a major impact on morbidity and mortality. In light of recent findings, AH in children has been interpreted as early cardiovascular disease (CVD), while exposure to CV risk factors in children proves to be a predictor of subclinical CVD in adults. The American College of Cardiology/American Heart Association has recently updated the classifications for measuring blood pressure (BP) in adults and children. Primary AH in children is genera...
Source: Jornal Brasileiro de Nefrologia - May 3, 2024 Category: Urology & Nephrology Authors: Vera Hermina Kalika Koch Erika Arai Furusawa Source Type: research
Metabolic Syndrome and the Risk of Kidney Stones: a Large-scale Cohort Study from 487,860 UK Biobank participants
CONCLUSION: Metabolic syndrome is a significant and independent risk factor for the development of kidney stones. This association suggests that kidney stones may represent a systemic disorder influenced by the interplay of various metabolic risk factors.PMID:38701346 | DOI:10.1210/clinem/dgae295 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - May 3, 2024 Category: Endocrinology Authors: Minghui Liu Meng Gao Jian Wu Zewu Zhu Jiao Hu Hequn Chen Zhiyong Chen Jinbo Chen Source Type: research
The impact of systemic administration of polyphenols on periodontitis associated with diabetes mellitus: a systematic review
CONCLUSIONS: Despite the promising results observed in the included studies, the overall evidence supporting the positive effects of polyphenols on periodontal and diabetes mellitus status, along with their anti-inflammatory properties, remains inadequate.PMID:38700145 | DOI:10.2340/aos.v83.40484 (Source: Acta Odontologica Scandinavica)
Source: Acta Odontologica Scandinavica - May 3, 2024 Category: Dentistry Authors: Kornelija Rogalnikovaite Auste Antipoviene Asta Burbulyte Egle Aida Bendoraitiene Source Type: research
Humoral Response After Two Doses of COVISHIELD < sup > TM < /sup > Vaccine in Patients Undergoing Maintenance Hemodialysis
CONCLUSION: In MHD patients, two doses of the COVISHIELDTM vaccine induced a substantial humoral response. Prior history of COVID-19 resulted in a higher antibody response. Thus, the COVISHIELDTM vaccine is efficacious and safe for use in patients with MHD. How to cite this article: Balwani MR, Pasari AS, Baw.ule C, et al. Humoral Response After Two Doses of COVISHIELDTM Vaccine in Patients Undergoing Maintenance Hemodialysis. J Assoc Physicians India 2023;71(9):56-60.PMID:38700302 | DOI:10.59556/japi.71.0313 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Manish R Balwani Amit S Pasari Charulata Bawankule Amol Bhawane Priyanka Tolani Vijay M Katekhaye Source Type: research
Glycemic Control and Mucormycosis during COVID-19 Pandemic in India a Study of Stage and Outcome
CONCLUSION: The study showed a positive correlation between the stage of mucormycosis and serum glycemic control markers at presentation. Clinicians must order blood sugar and HbA1c levels at presentation as cues for a better understanding of disease severity. A thorough clinical examination and history taking for patient risk factors predisposing to mucormycosis are also crucial since the presence of proptosis and coronary artery disease are significantly correlated with the mortality outcomes. The extent of poor glycemic control at presentation was not associated with mortality outcomes. How to cite this article: Sharma ...
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Vagisha Sharma Kushal Kriplani Isha P Tuli Shilpam Sharma Anurag Narula Source Type: research
Dysbiosis in Irritable Bowel Syndrome
J Assoc Physicians India. 2023 Sep;71(9):75-81. doi: 10.59556/japi.71.0353.ABSTRACTThe human gut microbiota fosters the development of a dynamic group of microorganisms impacted by diverse variables that include genetics, diet, infection, stress, ingested drugs, such as antibiotics and small intestine bacterial overgrowth (SIBO) as well as the gut microbiota itself. These factors may influence the change in microbial composition, which results in dysbiosis (microbial imbalance) and exposes the gut to pathogenic insults. Dysbiosis is incidental to the etiology of inflammatory diseases such as irritable bowel syndrome (IBS) ...
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Philip Abraham Nitesh Pratap Source Type: research
Early Gestational Diabetes Mellitus: An Update
J Assoc Physicians India. 2023 Sep;71(9):101-103. doi: 10.59556/japi.71.0351.ABSTRACTHyperglycemia occurring in pregnancy is a growing burden worldwide. It is now standard of care to screen all women during pregnancy, both to detect preexisting diabetes as well as gestational diabetes mellitus (GDM). Traditionally, GDM was diagnosed at 24-28 weeks. However, with many international bodies recommending screening at first contact or booking, we are now diagnosing GDM earlier on in pregnancy. Based on the time of gestation at which it is diagnosed, GDM can be classified as conventional gestational diabetes mellitus (cGDM) or e...
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Wesely Hannah Rajendra Pradeepa Ranjit Mohan Anjana Ram Uma Mangesh Tiwaskar Viswanathan Mohan Source Type: research
