Tuberculosis-A Tough Bug.
Authors: Vora A PMID: 31315316 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Immune Checkpoint Inhibitors Discovery Bag the Nobel.
Authors: Londhey V PMID: 31315317 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Socio-economical and Clinico-Radiological Profile of 474 MDR TB Cases of a Rural Medical College.
Conclusion: The epidemiological picture of TB showed that males were predominant in our study however female were more affected in younger age group compared to male. More than 51% of the cases were in productive age group which affects the socioeconomic condition of family and society. More than 2/3 of patients were from lower socioeconomic group with low BMI. Therefore improving nutrition and immunity can play an important role. 2.3% of the cases were HIV reactive and were on ART. Co-morbidities like COPD and Diabetes were seen in our study which were statistically significant and had impact on the treatment outcome of r...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Urbanization, Human Development and Literacy and Syndemics of Obesity, Hypertension and Hyperglycemia in Rajasthan: National Family Health Survey-4.
Conclusion: There is significant geographic variation in prevalence of obesity, hypertension and hyperglycemia in Rajasthan. Significant correlation of obesity and hypertension with urbanization, human development and female literacy is observed.. PMID: 31315319 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Knowledge and Awareness of the Health Care Workers about the Hepatitis B Infection and their Vaccination Status in a Newly Started Medical College.
Conclusion: To conclude, the study highlights good knowledge about hepatitis B infection with requirement of more emphasis on the practical aspects of management in a case of NSI/blood splash and can guide to improve the vaccination status and knowledge of HBI amongst HCWs. PMID: 31315320 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Catheter Related Right Atrial Thrombus in Patients on Maintenance Hemodialysis: Results of a Single Centre Retrospective Study from a Tertiary Care Hospital.
Conclusion: The incidence of CRAT in patients with THC for MHD was 17.9%. Patients with THC for MHD should be examined for presence of CRAT before removal of THC to prevent fatal pulmonary thromboembolism. PMID: 31315321 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Association of Plasma Procalcitonin with Various Components of Metabolic Syndrome and Insulin Resistance in Urban Indian Population: A Novel Biomarker.
Authors: Bajpai D, Pednekar S, Pandey D, Moulick ND, Humane D, Bedmutha K Abstract Rationale: Chronic low-grade inflammation is proposed as the keystone in pathogenesis of metabolic syndrome. The inflammatory biomarker Procalcitonin which is produced by adipose tissue, can serve as a biomarker for insulin resistant state present in metabolic syndrome. Objectives: To evaluate the association of plasma Procalcitonin (PCT) with components of metabolic syndrome (abdominal obesity, dyslipidemia, hypertension, and hyperglycemia) and with insulin resistance as compared to healthy controls. Design: In this case-con...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Adherence of Observational Studies Published in Indian Journals to STRO BE Statement.
Conclusion: The overall reporting was suboptimal. The completeness of reporting did not differ in the three types of observational study designs. PMID: 31315323 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Thrombophilia Profile of Portal Vein Thrombosis in Young.
Authors: Rajesh C, Manrai M, Dubey AP, Shukla R, Jha A, Kapoor R Abstract The abdominal vein thrombosis is an unusual and rare, but potentially a life threatening form of thrombosis. Much is known, studied and published about the venous thrombosis in the lower limbs and to some extent in upper limbs, where as the abdominal vein thrombosis still remains an unexplored area. The diagnosis of abdominal venous thrombosis has increased with awareness of the entity and the availability of better imaging modalities. Despite advances made in the management of venous thrombosis, the knowledge of events predisposing to abdomi...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Efficacy of SGLT2 Inhibitors as the Fifth Drug in the Management of Type 2 Diabetes Mellitus in Asian Indians not Controlled with at least 4 Oral Antidiabetic Drugs.
Authors: Panikar V, Joshi SR, Deogaonkar N, Vadgama J, Nasikkar N, Kamat T, Sheikh S, Jain CC, Wagle T Abstract Aim: To evaluate the efficacy of SGLT2 inhibitors as an add-on therapy along with stricter lifestyle modification in Asian Indian type 2 diabetes mellitus (T2DM) patients with inadequate glycemic control despite receiving an optimum dose of at least 4 oral antidiabetic drugs (OADs). Methodology: A retrospective analysis of data of 808 T2DM patients being treated with an SGLT2 inhibitor (Dapagliflozin, Empagliflozin or Canagliflozin) as an add-on drug in patients with inadequate glycemic control despit...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Efficacy and Safety of Oral Tolvaptan Therapy in Hospitalized Cirrhotic Patients with Hyponatremia.
Authors: Garg R, Kaur K, Aggarwal S, Singh N Abstract Background: Tolvaptan is an orally administered, nonpeptide, selective arginine vasopressin V(2) receptor antagonist that increases free water clearance, thereby correcting and increasing the low serum sodium levels in patients of cirrhosis, where hyponatremai is am major encountered problem. Aims: Evaluate the efficacy and tolerabilty of tolvaptan in cirrhotics with symptomatic hyponatremia that resist correction with fluid restriction. Intellectual improvement assessed using Short Portable Mental Status Questionnaire (SPMSQ) pre and post therapy(on conclus...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Etiological Patterns, Liver Fibrosis Stages and Prescribing Patterns of Hepato-Protective Agents in Indian Patients with Chronic Liver Disease.
Conclusion: NAFLD is emerging as a predominant etiology of CLD in India, followed by ALD, HBV, and HCV. However, significant regional differences regarding predominant etiology was noted within the country. It was further noted that significant number of patients had advanced fibrosis based on VCTE assessment. This study emphasizes the need for appropriate risk evaluation and early assessment of severity of liver disease, for adequate disease management. PMID: 31315327 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Early Detection of Right Ventricular Dysfunction in Chronic Obstructive Pulmonary Disease by Echocardiography.
This study is designed to investigate the effects of pulmonary arterial hypertension on RV systolic and diastolic functions in cases of COPD and to correlate RV systolic and diastolic functions with pulmonary arterial pressure. Materials and Methods: 100 patients admitted in various medical wards of tertiary care Hospital and a primary care hospital with stable chronic obstructive pulmonary disease persons with age and sex-matched. 35 age and sex matched person without any associated and known disease were taken as control subjects. Selection of cases has been made on basis of detailed history, thorough clinical examin...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Emerging Landscape of Antibiotic Resistance and Use of Endoscopic Injection in Vesicoureteral Reflux.
Authors: Roy P, S R, MittalMittal R, Mehta S Abstract Vesicoureteral reflux (VUR) in children is often treated with antimicrobials for prolonged durations, which often leads to antimicrobial resistance. In this context, this review article discusses the use of endoscopic injection in VUR as a safe and efficacious option for these children. The literature pertaining to VUR- its clinical manifestation and management, antibiotic resistance- with special reference to management of VUR, and endoscopic dextranomer/hyaluronic acid gel injection for management of VUR was reviewed by identifying key words in a PubMed search...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Neurological Emergencies in Pregnancy.
This article reviews the clinical features and management of some of the common severe neurological emergencies in pregnancy. PMID: 31315330 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Secukinumab Use in Psoriatic Arthritis.
Authors: Jagdish RK, Shailly, Bhatnagar MK PMID: 31315331 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Tinea Pseudo-imbricata.
Authors: Meena M, Mittal A PMID: 31315332 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Hypereosinophilia with Multi-organ Dysfunction - A Diagnostic Conundrum.
Authors: Mittal A, Ray A, Jadon RS, Manchanda S, Naik SR, Singh K, Ranjan P, Vikram NK Abstract Eosinophils are predominantly tissue-dwelling cells (spleen, lymph nodes, thymus, digestive tract) and counts
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

46 XX, SRY Negative Ovotesticular DSD.
We report here a 20 year old phenotypically male who presented with gynaecomastia and found to have testis on right side and left inguinoscrotal swelling consisting of ovary, uterus and fallopian tubes. Evaluation revealed SRY negative 46 XX karyotype. He underwent surgical removal of ovary and mullerian structures. The highlight of case is development of testicular tissue in absence of SRY gene. PMID: 31315334 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Recurrent Prosthetic Pulmonary Valve Endocarditis in Repaired Tetralogy of Fallot.
Authors: Arora H, Mohan R, Agrawal D, W.hade P, Sachdeva S, Nindra P Abstract 25 year old male who was a known case of repaired Tetralogy of Fallot with history of early prosthetic pulmonary valve fungal endocarditis in 2012 presented in 2016 with history of prolonged fever. On subsequent work up, he was diagnosed to have recurrent fungal prosthetic pulmonary valve endocarditis. PMID: 31315335 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

An Unusal Site of Infective Endocarditis after Surgical Trauma-Evaluated by Three Dimensional Echocardiography.
Authors: Ratan P, Dwivedi P, Kharwar R, Kumar P PMID: 31315336 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Myocardial Infarction following Organophosphorus Compound Poisoning.
We report a 22 year old male who was admitted to our hospital with alleged history of consumption of monocrotophos poison and had presented with chest pain. His electrocardiogram (ECG) had showed ST segment elevation myocardial infarction and troponins were elevated. He also had low cholinesterase levels and was treated with pralidoxime and atropine and his condition improved. Cardiac catheterization showed patent coronaries. Acute coronary syndrome is a rare manifestation of organophosphorus compound (OPC) poisoning. The current case and subsequent review of literature tells us the need for close cardiac monitoring of all...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

DNA Discovery-Teamwork.
Authors: Pai-Dhungat J PMID: 31315338 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Uttar Pradesh Association of Physicians of India Position Statement: Betel Quid (Paan) and Diabetes.
The objective of this document is to offer clinical guidance for screening, diagnosis and management of co-occurring betel quid chewing among persons with Diabetes Mellitus (DM). The document aims to provide education and guidance to clinicians engaged in care and management of persons with DM, and improve access to treatment for co-occurring betel quid chewing among persons with DM. The current recommendation grades are based on published evidence, and categorized as strong, intermediate, weak and no evidence. The strength of these recommendations is based on the level of evidence. PMID: 31315339 [PubMed - in process]...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Indian Consensus on OPtimal Treatment of Angina (OPTA ).
Authors: Jadhav U, Pinto B, Jayagopal PB, Nair T, Kumar P, Sahoo PK, Ganguly A, Srivastava S, Kapoor S, Davidson D, Ahuja RC, Dharamadhikari A, Singh A PMID: 31315340 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Mobile Phone Involvement and Dependence among College Students.
Authors: Saha I, Som TK, Choudhury S, Ghose G, Patra M PMID: 31315341 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Subdural Haemorrhage Presenting with Isolated Unilateral 3rd Cranial Nerve Palsy.
Authors: Paul R, Gayen B, Sarkar R PMID: 31315342 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Post Malaria Neurological Syndrome and Vivax Malaria.
Authors: Shubhakaran K PMID: 31315343 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Topiramate Use and Angle Closure Glaucoma.
Authors: Shubhakaran K PMID: 31315344 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Dyspepsia Refractory to Conventional Measures in Patients with Rheumatoid Arthritis: Don't forget Helicobacter Pylori.
Authors: Dalal A PMID: 31315345 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Neurological Emergencies in HIV Patients.
Authors: Tiwari SB Abstract Introduction: HIV AIDS epidemic currently in India is quite under control, the efforts of NACO and community at large has lead to this. The current prevalence of HIV among adults is around) 0.3%, the widespread prevention and control strategies are the main reason behind the same. HAART coverage has also increased significantly which has played a major role in not only controlling the epidemic but also in the change of clinical scenario and clinical affection in patients of HIV AIDS. The neurological complications arising in HIV patients, either due to opportunistic infections or due to ...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Neurological Emergencies in HIV Infected Individuals at a Tertiary Hospital.
Authors: Nagarjunakonda S, Amalakanti S, Gollapudi S PMID: 31317700 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Evaluation of Plasma Homocysteine Levels in Patients of PCOS.
The objective was to evaluate the relationship between insulin resistance and serum homocysteine in subjects with polycystic ovarian syndrome (PCOS). Material and Methods: Cross sectional Case Control observational study done in Department of Obstetrics and Gynecology, KGMU Lucknow. Cases were 50 PCOS women as a study group and 40 women with infertility due to isolated male cause as a control group. Serum homocysteine levels compared in PCOS patients. Results: Mean homocysteine raised in cases (11.8 ± 5.5μmol/L) than control (7.8 ± 2.2 μmol/L), p
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Incidence of Type 2 Diabetes is Higher among Men with Persistent Impaired Glucose Tolerance than in Transient Impaired Glucose Tolerance - A 5 year Follow up Study.
Authors: Raghavan A, Nanditha A, Snehalatha C, Vinitha R, Susairaj P, Simon M, Selvam S, Satheesh K, Ram J, Kumar APN, Godsland IF, Oliver N, Johnston DG, Ramachandran A Abstract Objective: This was a 5 year comparative analysis of the incidence of type 2 diabetes in men who had persistent impaired glucose tolerance (P-IGT) versus transient impaired glucose tolerance (T-IGT). P-IGT (positive IGT on two oral glucose tolerance tests (OGTT), T-IGT (IGT in first OGTT and normal glucose tolerance (NGT) in the 2nd OGTT). Methods: The samples were collected from a randomized controlled diabetes prevention study. The p...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Study of Pulmonary Function Test Abnormalities in Metabolic Syndrome.
Authors: Chaudhary SC, Kumari T, Usman K, Sawlani KK, Himanshu D, Gupta KK, Patel ML, Agarwal A, Verma AK Abstract Introduction: Metabolic Syndrome (MetS) is defined as a constellation of an interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of atherosclerotic cardiovascular disease and T2DM. Although the link between impaired lung function and cardiovascular events and T2DM has been recognized, the association between impaired lung function and MetS has not been comprehensively assessed. Material and Methods: A cross sectional prevalence study was done i...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Study of Correlation between Diabetic Pulmonopathy with Serum Adiponectin Levels in Patients of Type 2 Diabetes Mellitus.
Authors: Kumar S, Gupta A, Sameja P, Patel I, Gupta S Abstract Diabetes mellitus a disease with various macro and micro vascular complications due to its various metabolic dysregulations, is well known to involve lungs in long run in both type 1 and 2 diabetes mellitus, causing tremendous burden on health care system. Common simple lung function tests alone are likely to underestimate the prevalence and degree of lung dysfunction in diabetes, but newer noninvasive tests of lung mechanical function provide a more sensitive assessment of peripheral airway function, hence by establishing a marker and risk factors for ...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Validity of Indian Diabetes Risk Score (IDRS) in Population in and Around Agra.
Authors: Chaturvedi M, Pandey A, Javed M, Baiswar R Abstract India leads the world with largest number of Diabetic subjects earning the dubious distinction of "Diabetic Capital of the world." Every 5th patients visiting a physician is diabetic. Epidemiological data from various parts of country show a rising prevalence of diabetes. India faces a grave health care burden due to high prevalence of Type-2 diabetes and its sequelae. The brunt of disease is that type 2 DM frequently remains undiagnosed until its complications appear. Early detection and prompt treatment may reduce the burden of disease and its...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Toe Brachial Pressure Index as Alternative Method to Correlate Arteriosclerotic Disease in Type 2 Diabetes.
Conclusion: We studied 81 type 2 diabetic patients, with established cardiovascular disease, consecutively admitted to our outpatient clinic in the Division of Diabetes of La Paz Hospital. We collected clinic and demographic data, ABI and TBI were measured and at the same time a carotid Doppler ultrasound was performed. Multiple linear regression analysis was used to investigate the association of ABI and TBI with carotid disease. We found a negative correlation between TBI and internal carotid artery peak systolic velocity (ICA PSV) (r = -0,300, p= 0,007), common carotid artery resistance index (CCA RI) (r = -0,232, p= 0,...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Correlation of D-Dimer Level with the Presence and Severity of Pulmonary Embolism on Computed Tomography Pulmonary Angiography.
Conclusion: D-dimer value more than 4000 ng/ml had high positive prediction value (79%) in suspected clinical cases. Value more than 8000 ng/ml further improve value to nearly 100% in suspected cases. PMID: 31317707 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Evaluation of serum Glutathione-S Transferase-Alpha as a Biomarker of Intrahepatic Cholestasis of Pregnancy.
Authors: Shukla A, Saxena P, Yadav A Abstract Objective: To evaluate if serum Glutathione-S Transferase-Alpha (GSTA) can be used as a biomarker of intrahepatic cholestasis of pregnancy (IHCP). Methods: 45 pregnant women with IHCP and 45 age and weight matched pregnant women as controls were enrolled and liver function tests including serum GSTA were measured. All cases and controls were followed for their maternal and foetal outcomes till delivery. Statistical analysis included unpaired t test, Mann-Whitney test and chi square test. Results: IHCP group showed higher mean serum GSTA concentrations compared t...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Subject Profile Assessment of Cases Recommended with Nutritional Supplement Containing Red Yeast Rice, Grape Seed Extract and Black Pepper Extract: A Prospective, Multicentric, Post-marketing Study.
Authors: Shah S, Rajagopal N, Shah B, Biswas AD, Hiremath J, Bansal R Abstract Objective: To assess the profile and general health indices in subjects prescribed with a nutritional supplement containing red yeast rice, grape seed extract and black pepper extract (NS-YGP; PreLipid®; Abbott Healthcare Pvt. Ltd.) in routine clinical setting in India. Methods: In this prospective, postmarketing observational study, consecutive subjects recommended NS-YG at their outpatient department were recruited from 39 sites in India. The primary outcome of interest was to identify the profiles of subjects recommended with ...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Knowledge about Informed Consent among Doctors of Various Specialities: A Pilot Survey.
Conclusion: Significant knowledge gaps were identified. There were deficiencies in providing correct response particularly in practical scenarios. There is a need to include knowledge about different aspects of informed consent in the medical curriculum. PMID: 31317710 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

A Case Series on the Recent Nipah Epidemic in Kerala.
Authors: Thulaseedaran NK, Kumar KGS, Kumar J, Geetha P, Jayachandran NV, Kamalasanan CG, Mathew S, Pv S Abstract During May 2018 there occurred an outbreak in Kerala, which started in Soopikkada Village, Changarothu Grama Panchayath in Perambra Taluk, Kozhikode district, of a febrile illness with altered sensorium and ARDS. The diagnosis was made from the second case that it is the dreaded nipah infection. Following that 18 cases tested positive for nipah virus infection of which 2 survived. Also there were four deaths with similar clinical picture but which occurred before the virus was identified. They were cons...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Tropical Coinfections: Clinical Implications.
Authors: Yeolekar ME PMID: 31317712 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Inhibition: A Lipocrinologic Review.
Authors: Kalra S Abstract This review describes the endocrine impact of proprotein convertase subtilisin kexin 9 (PCSK9) biology and PCSK9 inhibition. It discusses the relationship of the pituitary, thyroid, parathyroid, pancreatic, adrenal and gonadal hormones with lipid health. It also explores the status of PCSK9, and impact of PCSK9 inhibition, in dyslipidemia associated with endocrinopathy. This review should stimulate interest in the lipocrinologic aspects of PCSK9 inhibitors. PMID: 31317713 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Pharmacotherapy of Chronic Rhinosinusitis with a Focus on Clarithromycin: An Expert Opinion.
Authors: Bhargava SK, Peethambaran K Abstract Chronic Rhinosinusitis (CRS) is frequently distinguished as persistent symptomatic inflammation of the nasal and sinus mucosa and is recognized as one of the most common chronic diseases, with high incidence rate. It has a major impact on overall quality of life. Although, the etiology and pathogenesis of CRS are not clearly understood, there are several hypotheses on CRS etiology and pathogenesis. The presence of biofilms and bacterial infection, as well as fungal infection, allergy, environmental pollutants, and smoking are considered as a possible environmental facto...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Bilateral Calcified Renal Artery Aneurysms: Not every Calcification is a Calculus!
Authors: John NT PMID: 31317715 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

"Amyloid Spells" - An Unusual TIA Mimic.
"Amyloid Spells" - An Unusual TIA Mimic. J Assoc Physicians India. 2018 Oct;66(10):81 Authors: Chauhan A, Divate PG PMID: 31317716 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Dengue Fever as a Rare Cause of Acute Pancreatitis.
Authors: Nawal CL, Meena PD, Chejara RS, Jain S, Marker S, Tuteja V Abstract Dengue is an arthropod borne viral infection endemic in tropical and subtropical climate. Here we report an unusual presentation of Dengue fever as acute pancreatitis. Timely recognition of such atypical complication can reduce the morbidity and mortality. PMID: 31317717 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Pulmonary Embolism Mimicking Acute Severe Asthma.
Authors: Bansal DP, Maazuddin M, Viquasuddin M Abstract When a patient presents with wheezing, pulmonary embolism is not usually considered as a possible cause. However bronchoconstriction can be caused by the embolism which produces wheezing that may be so obvious to make a diagnosis of bronchial asthma. Here we present a case of sub-massive pulmonary embolism presenting predominantly with wheezing without any previous history of cardio pulmonary diseases. The patient was treated for acute severe asthma in the beginning later suspected to have pulmonary embolism because of poor response to therapy and was confirme...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research