Tocilizumab or no Tocilizumab - To be or not to be.
Authors: Gokhale Y PMID: 33527803 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Itolizumab Treatment for Cytokine Release Syndrome in Moderate to Severe Acute Respiratory Distress Syndrome Due to COVID-19: Clinical Outcomes, A Retrospective Study.
Conclusion: A single dose of Itolizumab accelerated recovery in adult patients with COVID-19 by controlling immune hyperactivation. The clinical improvement was demonstrated by reduction in inflammatory markers, weaning off oxygen, reduced length of hospital stay and improvement of ordinal score. Itolizumab was well tolerated and when administered in the early phase of the inflammatory cascade is an efficient therapeutic option for treatment of cytokine release syndrome in moderate to severe COVID-19 patients. PMID: 33527804 [PubMed - indexed for MEDLINE] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Liver Function Status in COVID-19: An Indian Perspective.
Conclusion: Derangements of LFT in COVID-19 Patients are common especially in patients with severe disease but its long term impact is unknown. Hence, further investigation and long term follow up of recovered COVID-19 cases is warranted to understand the pathophysiology and implication of liver injury that occurs both in overt and covert forms during infection. PMID: 33527805 [PubMed - indexed for MEDLINE] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Exercise Prescription in Diabetes- S.M.A.R.T.: A Prospective Study.
Discussion: Recommending exercise and lifestyle changes is as important as pharmacological management in diabetes. A SMART approach, methodical prescription of the exercise routines and drugs- individualized for patients, will likely have better results and patient satisfaction. A practice of switching to precise written suggestions than verbal ideas and reviewing the progress on every follow up visit may improve the outcome. PMID: 33527806 [PubMed - indexed for MEDLINE] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Clinical Evidence of Evogliptin plus Metformin in Management of Type 2 Diabetes mellitus.
Authors: Bajaj S, Aiwale A, Trailokya A, Sharma A Abstract Achieving adequate glycemic control in type 2 diabetes mellitus (T2DM) remains a difficult but achievable goal. Oral agents (OADs) are important option for management of T2DM. Most T2DM patients require more than one medication for adequate glycemic control. Metformin based combination therapy is recommended when monotherapy is insufficient. Evogliptin is a recently developed dipeptidyl peptidase-4 (DPP-4) inhibitor, which can to be combined with metformin for treating T2DM. Combination therapy of Evogliptin and Metformin lowers blood glucose via augmentati...
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Diabetic Foot Care Knowledge and Practices in Rural North India: Insights for Preventive Podiatry.
Authors: Verma M, Sharma N, Rashi, Arora V, Bashar MA, Nath B, Kalra S Abstract Background: Diabetic foot ulcer (DFU) is one of the most dreaded complications of Type 2 Diabetes Mellitus (T2DM). Preventive podiatry is most efficient way of minimising DFU. The main aim of the study was to assess the knowledge and foot care practices among patients living with T2DM concerning the DFU. Materials and Methods: We conducted a cross-sectional study in a rural-area of Haryana, India between January to March 2019 amongst 416 people living with T2DM after using multistage random sampling. A pre-tested, structured survey ...
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Evaluation of the Efficacy and Safety of Azilsartan in Adult Patients with Essential Hypertension: A Randomized, Phase-III Clinical Study in India.
Conclusion: Azilsartan is an effective blood pressure lowering drug and well tolerated and was non- inferior to telmisartan in its safety and efficacy. PMID: 33527809 [PubMed - indexed for MEDLINE] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Study of Endothelial Dysfunction by Flow Mediated Vasodilation in Individuals with Asymptomatic Hyperuricemia.
Conclusion: The present study showed that significant endothelial dysfunction is present in individuals of asymptomatic hyperuricemia in comparison to healthy age and sex matched controls. PMID: 33527810 [PubMed - indexed for MEDLINE] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Impact of Thyroid Dysfunction on Insulin Resistance: A Study from a Tertiary Care Center in India.
Authors: Srivastava S, Mathur G, Chauhan G, Kapoor P, Bhaskar P, Jain G, Chauhan G, Chopra M Abstract Introduction: The thyroid hormones perpetuate a fine equilibrium of glucose metabolism. Abnormalities of thyroid function can disrupt this balance leading to glucose metabolism abnormalities and insulin resistance. Objectives: We studied the correlation between insulin resistance and thyroid status in hyperthyroid, euthyroid, and hypothyroid individuals. Methods: In this observational comparative analysis conducted at a tertiary care center, the 3 study groups comprised of 35 patients each with newly detect...
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Ethambutol Optic Neuropathy: Vigilance and Screening, the Keys to Prevent Blindness with the Revised Anti-tuberculous Therapy Regimen.
Authors: Saxena R, Phuljhele S, Prakash A, Lodha R, Singh D, Karna S, Mohan A, Gandhi R, Menon V, Garg R, The Inosrg Abstract There has been change in the guidelines for the management of tuberculosis in India. The new guidelines advocate the daily use of Ethambutol for both intensive and continuation phase of the treatment. This may be a matter of concern as increased cumulative dose may lead to increase in incidence of toxic optic neuropathy due to ethambutol. Indian Neuro-Ophthalmology Society has taken cognizance of the issue and has come-up with guidelines for prevention and early detection of the toxic optic ...
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

New and Unique Clusters of Type 2 Diabetes Identified in Indians.
Authors: Anjana RM, Pradeepa R, Unnikrishnan R, Tiwaskar M, Aravind SR, Saboo B, Joshi SR, Mohan V Abstract Type 2 diabetes (T2D), the most common form of diabetes, is recognized as being a heterogenous disorder, and presents a universal threat to health. In T2D, the pathophysiology and phenotype differ significantly by ethnicity, particularly among Asian Indians, who are known to have the 'Asian Indian phenotype', which makes them more susceptible to develop T2D than white Caucasians. The recent subclassification of T2D into different subtypes or clusters, which behave differently with respect to clinical presenta...
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Effective Written Communication in Consult Letters: A Crucial Yet Overlooked Skill?
Authors: Deep R Abstract The consult letters can be viewed as a window to the entire consultation process. Suitable drafting of consult letters is a useful but often overlooked skill in training years. It is not uncommon to find the consult notes lacking the relevant context or clinical information. Both the style and content should be kept in mind for an effective written communication. It is also important to supervise and give specific feedback to the trainees to make the consult letters succinct and clear. PMID: 33527814 [PubMed - indexed for MEDLINE] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Seven-and-a-Half Syndrome.
Authors: Sharda M, Jain P, Bauddh NK, Meena JK, Sharma Y PMID: 33527815 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Pneumocephalus.
Authors: Mehta SK, Poddar A PMID: 33527816 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Quadricuspid Aortic Valve.
Authors: Mazumdar P, Shrivastava P, Vidyapati, Das M PMID: 33527817 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Primary Central Nervous System Lymphoma (PCNSL) - A Rare and Unusual Presentation of Rapidly Progressive Major Cognitive Dysfunction.
We report a case of PCNSL as a rare and unusual presentation of rapidly progressive cognitive dysfunction which revealed clinicopathoradiological correlation. The patient revealed clinicoradiologically evident marked improvement after treatment, ascribing PCNSL as potentially reversible cause of major cognitive dysfunction. PMID: 33527818 [PubMed - indexed for MEDLINE] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Fatal Cutaneous Zygomycosis caused by Saksaenea Vasiformis.
Authors: Patel V, Shah V Abstract Fungi in the class of zygomycetes usually produce serious infections in diabetics and immunocompromised hosts. Cutaneous zygomycosis is a less common form, with an unpredictable extent of anatomical involvement and clinical course1.¹ Here, we report a case of primary cutaneous zygomycosis caused by saksaenea vasiformis as posttraumatic complications in a diabetic female. Zygomycosis was suspected and specimens from the surgical debridement were examined by microbiological and histopathological studies for conforming the clinical diagnosis. Rapid diagnosis, liposomal amphoteric...
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Mycotic Aneurysm of Brachial Artery in Case of Aplastic Anemia.
We report a patient with aplastic anemia who developed pseudoaneurysm of the brachial artery following an episode of bacterial sepsis. Methicillin resistant Staphylococcus aureus (MRSA) was isolated on blood culture. Patient was treated with systemic antibiotics and underwent embolization of the pseudo-aneurysm. He later developed vascular insufficiency of the forearm and a stent had to be placed in the brachial artery at the site of calcified thrombus inside the pseudo-aneurysm to produce the patency of the artery and ensure adequate blood flow to forearm and hand. PMID: 33527820 [PubMed - indexed for MEDLINE] (Source...
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Central Visual Process- Hubel & Weisel.
Central Visual Process- Hubel & Weisel. J Assoc Physicians India. 2021 Feb;69(2):75 Authors: Pai-Dhungat J, Gore G PMID: 33527821 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Over-coming Challenges in Conducting Postgraduate Practical Examination during COVID -19 Pandemic.
Authors: Dhar M, Gupta R, Rao S, Kant R PMID: 33527822 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

"COVID 19"- A New Baby in the Family of Viruses Causing Arthropathy: Don't Overlook it can be First Manifestation of Severe COVID Infection.
"COVID 19"- A New Baby in the Family of Viruses Causing Arthropathy: Don't Overlook it can be First Manifestation of Severe COVID Infection. J Assoc Physicians India. 2021 Feb;69(2):77 Authors: Pandey A, Agrawal P, Pursnani N, Maheshwari PK, Gautam A PMID: 33527823 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Morbidity Among Home Isolated COVID-19 Patients.
Authors: Rai D, Sahay N, Pandey S PMID: 33527824 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - February 4, 2021 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Fighting the Atherosclerotic Cardiovascular Disease Epidemic: Declaring War on Lipids by Lipid Association of India.
Authors: Mehta V, Iyengar SS, Yusuf J, Mukhopadhyay S, Sattur GB, Puri R PMID: 33350609 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Lipid Association of India Expert Consensus Statement on Management of Dyslipidemia in Indians 2020: Part III.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350610 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Lifestyle Modification in the Prevention of Atherosclerotic Cardiovascular Disease.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350611 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Low Density Lipoprotein Cholesterol Targets in Secondary Prevention of Atherosclerotic Cardiovascular Disease.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350612 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Triglycerides and Atherosclerotic Cardiovascular Disease.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350613 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Lipoprotein(a) and ASCVD risk.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350614 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

High Sensitivity C-Reactive Protein.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350615 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Apolipoprotein B as a Predictor of CVD.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350616 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Non-HDL Cholesterol and Atherosclerotic Cardiovascular Disease.
Authors: Puri R, Mehta V, Iyengar SS, Narasingan SN, Duell PB, Sattur GB, Vijayaraghavan K, Mohan JC, Wangnoo SK, Dalal J, Prabhakar D, Agarwal R, Bansal M, Yusuf J, Mukhopadhyay S, Shetty S, Manoria PC, Sabharwal A, Pradhan A, Mehrotra R, Mishra S, Puri S, Muruganathan A, Zargar AH, Patanwala RM, Kumar S, Bardoloi N, Pareek KK, Kapoor A, Rastogi A, Nair DR, Shaikh A, Adhikari CM, Majumder MSM, Kapoor D, Yadav M, Mubarak MR, Pancholia AK, Sahay RK, Nanda R, Wong ND PMID: 33350617 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - December 24, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Health Care Workers in Covid-19: From Lockdown to Unlock and Beyond!
Authors: Londhe C, Londhey V PMID: 33247635 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Hepatitis C: A Tale of Three Nobel Laureates and the Ladder to Elimination.
Authors: Singh A, Sundaram S, Shukla A PMID: 33247636 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Prevalence, Clinical Presentations and Treatment Outcomes of COVID-19 among Healthcare Workers at a Dedicated Hospital in India.
Authors: Mahajan NN, Mathe A, Patojar GA, Bahirat S, Lokhande PD, Rakh V, Gajbhiye R, Rathi S, Tilve A, Mahajan K, Mohite SC Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is rapidly spreading in India and across the world. Healthcare workers (HCWs) are at increased risk of contracting COVID-19 due to direct or indirect exposure to COVID-19 patients, and require special attention. Limited information is available about its effect in HCWs. Secondary transmission from HCWs is a possibility among patients, family members, and the community. Therefore, it is important to investigate the...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Physician Health in the Times of COVID-19.
Authors: Bavdekar SB, Chandrasekaran A, Govindarajan RP, Malik S, Bajaj S, Javeri Y, Niranjan V Abstract Background and Objectives: A virtual registry study evaluating real world evidence on physicians' use of prophylactic regimens for protection against SARS-CoV-2. This paper summarizes the interim results. Methods: Asymptomatic physicians at risk of acquiring SARS-CoV-2 responded to online questions at baseline and 7 weeks post-baseline. Baseline data included demographics, prophylaxis regimen (including "no prophylaxis") and start date. Participants who provided complete week-7 data (information on...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Nationwide Survey on the Knowledge, Attitudes and Perceptions among the Indian Adult Population regarding COVID-19.
Conclusion: Despite limitations of generalizability, this survey has identified areas which the public health authorities need to target in future information campaigns. PMID: 33247639 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Post COVID Inflammation Syndrome: Different Manifestations Caused by the Virus.
Conclusion: As the number of cases of COVID-19 cases has been increasing globally, it is advisable that physicians consider the possibility of post-COVID manifestations while examining patients with non-specific inflammation. A short course of NSAIDs and hydroxychloroquine regimen has been found to be beneficial for alleviating symptoms, and in rare cases with organ threatening inflammation, steroids may be required. PMID: 33247640 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Effectiveness of Convalescent Plasma Therapy in the Treatment of Moderate to Severe COVID 19 Patients: A Systematic Review and Meta-Analysis.
Authors: Meher BR, Padhy BM, Das S, Mohanty RR, Agrawal K Abstract Though Convalescent plasma therapy (CPT) is being used for management of COVID-19, the evidence is still equivocal. So, we carried out this study to evaluate the currently available data to provide evidence about CPT in COVD-19 patients. RCTs and observational studies with sample size with more than 5 were included in the analysis. Out of 196 studies, 12 studies were selected for systematic review and meta-analysis was carried out for 6 studies having a control arm. For dichotomous values, risk ratio (RR) and 95% confidence interval was expressed. ...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

The Syndromic Spectrum of COVID-19 and Correlates of Admission Parameters with Severity-outcome Gradients: A Retrospective Study.
Conclusion: Greater prevalence of symptoms (alone and in combination) and derangements in blood biochemistry are seen in severe COVID-19 compared to mild or moderate cases, and also in non-survivors compared to survivors. PMID: 33247642 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Status of Health-care Workers in Relation to COVID-19 Infection: A Retrospective Study in a Level 4 COVID Hospital in Eastern India.
Conclusion: Heath care workers are at higher risk of being exposed to SARS-CoV2 and could potentially has a role in transmission in and out of the hospital. Hence, routine screening of both symptomatic as well as asymptomatic hospital staff is essential for early diagnosis to prevent transmission of COVID 19 infection. PMID: 33247643 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Pancreatic Injury in COVID-19 Patients.
Conclusion: The prevalence of hyperamylasemia in patients of COVID-19 was 33%, while that of elevated lipase was 24.1%. Pancreatic injury failed to show any statistically significant relation to severity or outcome of COVID-19. PMID: 33247644 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Randomized Comparative Clinical Study of First Global Omalizumab Biosimilar with Innovator Product in Moderate to Severe Persistent Asthma.
Conclusion: The evaluation of pharmacokinetics, pharmacodynamics, efficacy, safety and immunogenicity was concluded to show no meaningful clinical difference of the biosimilar omalizumab with the reference product. PMID: 33247645 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Anosmia, Ageusia and COVID-19.
Authors: Ray PS Abstract COVID-19 is certainly the greatest global health problem now and for the foreseeable future. Clinicians and scientists from all over the world have been producing evidence to understand the epidemiology, clinical profile and prognostic factors of COVID-19. In the last six months a large list of COVID-19 symptoms including loss of taste and smell have emerged which can be used for screening and risk stratification. Robust workup of this evidence will help to reach strong conclusions to advance clinical medicine, epidemiology, public health, immunology and evidence-based treatment options in ...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

COVID-19 and Tuberculosis: A Meeting of Two Pandemics!
Authors: Gupta U, Prakash A, Sachdeva S, Pangtey GS, Khosla A, Aggarwal R, Sud R, Margekar SL Abstract Coronavirus disease 2019 (COVID-19), causes serious respiratory illness manifesting as pneumonia, adult respiratory distress syndrome and respiratory failure. Amidst the rising number of cases and deaths, it is imperative to not forget Tuberculosis (TB) which is another pandemic existing since centuries. There could be dire consequences for tuberculosis patients globally especially in low and middle income countries with a high burden of disease and overwhelmed health care systems. Tuberculosis is still the leadin...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Drug Resistant Seizure Disorder in Young Patient.
Authors: Panda PK, Agstam S, Mokta J, Sharma A, Sharma YP PMID: 33247648 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

An Interesting Case of Upper Gastrointestinal Bleed.
Authors: Manoria P PMID: 33247649 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Heerfordt-Waldenstr öm Syndrome.
We present such a case of Heerfordt-Waldenström syndrome. PMID: 33247650 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Case Reports of Two Interesting Patients with Sea Snake Envenomation.
Authors: Kumar SS, Ragunanthanan S, Ramesh D, Rajendran V, Sridhar S Abstract Sea Snakes have the most potent venom among snakes known to mankind and a few species are implicated in human fatalities.1 Commonest Sea snake in the Indian Sea is Enhydrina Schistosa.2 Mortality is high in spite of therapy because of multiple complications. This is a Case report of two Fishermen who were bitten by Sea Snake and developed complications. PMID: 33247651 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Animal Assisted Therapy.
Authors: Pai-Dhungat J, Verma A PMID: 33247652 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Beyond COVID-19: Evidence-Based Consensus Statement on the Role of Physiotherapy in Pulmonary Rehabilitation in the Indian Context.
The objective of this consensus statement is to provide evidence informed guidelines for post COVID-19 physiotherapy management as a component of pulmonary rehabilitation. This consensus statement was developed by expert panel across India. Published literatures were appraised and used to prepare the recommendations. This is the first of its kind of work providing preliminary guidelines for post COVID-19 physiotherapy. PMID: 33247653 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research