Health Care Workers in Covid-19: From Lockdown to Unlock and Beyond!
Authors: Londhe C, Londhey V PMID: 33247635 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Hepatitis C: A Tale of Three Nobel Laureates and the Ladder to Elimination.
Authors: Singh A, Sundaram S, Shukla A PMID: 33247636 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Prevalence, Clinical Presentations and Treatment Outcomes of COVID-19 among Healthcare Workers at a Dedicated Hospital in India.
Authors: Mahajan NN, Mathe A, Patojar GA, Bahirat S, Lokhande PD, Rakh V, Gajbhiye R, Rathi S, Tilve A, Mahajan K, Mohite SC Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is rapidly spreading in India and across the world. Healthcare workers (HCWs) are at increased risk of contracting COVID-19 due to direct or indirect exposure to COVID-19 patients, and require special attention. Limited information is available about its effect in HCWs. Secondary transmission from HCWs is a possibility among patients, family members, and the community. Therefore, it is important to investigate the...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Physician Health in the Times of COVID-19.
Authors: Bavdekar SB, Chandrasekaran A, Govindarajan RP, Malik S, Bajaj S, Javeri Y, Niranjan V Abstract Background and Objectives: A virtual registry study evaluating real world evidence on physicians' use of prophylactic regimens for protection against SARS-CoV-2. This paper summarizes the interim results. Methods: Asymptomatic physicians at risk of acquiring SARS-CoV-2 responded to online questions at baseline and 7 weeks post-baseline. Baseline data included demographics, prophylaxis regimen (including "no prophylaxis") and start date. Participants who provided complete week-7 data (information on...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Nationwide Survey on the Knowledge, Attitudes and Perceptions among the Indian Adult Population regarding COVID-19.
Conclusion: Despite limitations of generalizability, this survey has identified areas which the public health authorities need to target in future information campaigns. PMID: 33247639 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Post COVID Inflammation Syndrome: Different Manifestations Caused by the Virus.
Conclusion: As the number of cases of COVID-19 cases has been increasing globally, it is advisable that physicians consider the possibility of post-COVID manifestations while examining patients with non-specific inflammation. A short course of NSAIDs and hydroxychloroquine regimen has been found to be beneficial for alleviating symptoms, and in rare cases with organ threatening inflammation, steroids may be required. PMID: 33247640 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Effectiveness of Convalescent Plasma Therapy in the Treatment of Moderate to Severe COVID 19 Patients: A Systematic Review and Meta-Analysis.
Authors: Meher BR, Padhy BM, Das S, Mohanty RR, Agrawal K Abstract Though Convalescent plasma therapy (CPT) is being used for management of COVID-19, the evidence is still equivocal. So, we carried out this study to evaluate the currently available data to provide evidence about CPT in COVD-19 patients. RCTs and observational studies with sample size with more than 5 were included in the analysis. Out of 196 studies, 12 studies were selected for systematic review and meta-analysis was carried out for 6 studies having a control arm. For dichotomous values, risk ratio (RR) and 95% confidence interval was expressed. ...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

The Syndromic Spectrum of COVID-19 and Correlates of Admission Parameters with Severity-outcome Gradients: A Retrospective Study.
Conclusion: Greater prevalence of symptoms (alone and in combination) and derangements in blood biochemistry are seen in severe COVID-19 compared to mild or moderate cases, and also in non-survivors compared to survivors. PMID: 33247642 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Status of Health-care Workers in Relation to COVID-19 Infection: A Retrospective Study in a Level 4 COVID Hospital in Eastern India.
Conclusion: Heath care workers are at higher risk of being exposed to SARS-CoV2 and could potentially has a role in transmission in and out of the hospital. Hence, routine screening of both symptomatic as well as asymptomatic hospital staff is essential for early diagnosis to prevent transmission of COVID 19 infection. PMID: 33247643 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Pancreatic Injury in COVID-19 Patients.
Conclusion: The prevalence of hyperamylasemia in patients of COVID-19 was 33%, while that of elevated lipase was 24.1%. Pancreatic injury failed to show any statistically significant relation to severity or outcome of COVID-19. PMID: 33247644 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Randomized Comparative Clinical Study of First Global Omalizumab Biosimilar with Innovator Product in Moderate to Severe Persistent Asthma.
Conclusion: The evaluation of pharmacokinetics, pharmacodynamics, efficacy, safety and immunogenicity was concluded to show no meaningful clinical difference of the biosimilar omalizumab with the reference product. PMID: 33247645 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Anosmia, Ageusia and COVID-19.
Authors: Ray PS Abstract COVID-19 is certainly the greatest global health problem now and for the foreseeable future. Clinicians and scientists from all over the world have been producing evidence to understand the epidemiology, clinical profile and prognostic factors of COVID-19. In the last six months a large list of COVID-19 symptoms including loss of taste and smell have emerged which can be used for screening and risk stratification. Robust workup of this evidence will help to reach strong conclusions to advance clinical medicine, epidemiology, public health, immunology and evidence-based treatment options in ...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

COVID-19 and Tuberculosis: A Meeting of Two Pandemics!
Authors: Gupta U, Prakash A, Sachdeva S, Pangtey GS, Khosla A, Aggarwal R, Sud R, Margekar SL Abstract Coronavirus disease 2019 (COVID-19), causes serious respiratory illness manifesting as pneumonia, adult respiratory distress syndrome and respiratory failure. Amidst the rising number of cases and deaths, it is imperative to not forget Tuberculosis (TB) which is another pandemic existing since centuries. There could be dire consequences for tuberculosis patients globally especially in low and middle income countries with a high burden of disease and overwhelmed health care systems. Tuberculosis is still the leadin...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Drug Resistant Seizure Disorder in Young Patient.
Authors: Panda PK, Agstam S, Mokta J, Sharma A, Sharma YP PMID: 33247648 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

An Interesting Case of Upper Gastrointestinal Bleed.
Authors: Manoria P PMID: 33247649 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Heerfordt-Waldenstr öm Syndrome.
We present such a case of Heerfordt-Waldenström syndrome. PMID: 33247650 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Case Reports of Two Interesting Patients with Sea Snake Envenomation.
Authors: Kumar SS, Ragunanthanan S, Ramesh D, Rajendran V, Sridhar S Abstract Sea Snakes have the most potent venom among snakes known to mankind and a few species are implicated in human fatalities.1 Commonest Sea snake in the Indian Sea is Enhydrina Schistosa.2 Mortality is high in spite of therapy because of multiple complications. This is a Case report of two Fishermen who were bitten by Sea Snake and developed complications. PMID: 33247651 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Animal Assisted Therapy.
Authors: Pai-Dhungat J, Verma A PMID: 33247652 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Beyond COVID-19: Evidence-Based Consensus Statement on the Role of Physiotherapy in Pulmonary Rehabilitation in the Indian Context.
The objective of this consensus statement is to provide evidence informed guidelines for post COVID-19 physiotherapy management as a component of pulmonary rehabilitation. This consensus statement was developed by expert panel across India. Published literatures were appraised and used to prepare the recommendations. This is the first of its kind of work providing preliminary guidelines for post COVID-19 physiotherapy. PMID: 33247653 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

The COVID Infodemic - How Much is Too Much?
Authors: Chakrabarthi S, Narayan P PMID: 33247654 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Preface.
Authors: Menon S PMID: 33247655 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Foreword.
Authors: Mohan V PMID: 33247656 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Pre-Basal Insulin Analog Era: Paving the Way for Modern Day Basal Insulins.
Authors: Tiwaskar M, Deb P, Khadgawat R, Sreenivasamurthy L, Deka N, Karthik B, Karuppan A, Bhattacharjee D, Mohan V Abstract Prior to the discovery of insulins, diabetes was managed predominantly by dietary interventions. Discovery of insulin and its first human trial highlighted the need for higher purity insulin thereby steering the subsequent journey of insulin development. Considering the limitations of the early preparations like short duration of action and need for several injections per day, attempts at protracting the duration of insulin action were made. This led to the development of intermediate-acting...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Gla-100 Development: a Story of 'Serendipitous' Disruptive Innovation.
Authors: Badgandi M, Negalur V, Reddy PS, Venkataraman S, Kota S, Barman KK, Jayaprassad V, Pasha MY, Sruthisri P, Mohan V Abstract Ever since the discovery of insulin a century ago, relentless attempts have been made to develop insulins that closely mimic the timeaction- profile of human physiologic insulin. The early basal insulins like neutral protamine Hagedorn (NPH), were intermediate-acting, with high risk of hypoglycemia. These primary limitations led to attempts at developing improved basal insulins with a longer duration of action. After several attempts at prolonging insulin action using phenol and struct...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Two Decades of Gla-100-Reflections from the Pivotal Clinical Trials.
This article delineates clinical data on the effectiveness of Gla-100 vs. other insulin formulations in the context of T2DM. PMID: 33247659 [PubMed - as supplied by publisher] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Adoption of Gla-100 in India and its Impact on Insulin Usage Patterns.
Authors: Modi KD, Jha S, Banzal S, Bandopadhyay B, Ramchandani GD, Atluri S, Kumar RV, Kunder SK, Unnikrishnan R, Mohan V Abstract Fueled by perceptions regarding Indian dietary patterns and premixed insulin's claim to fame of providing dual fasting and post-prandial control, there was a greater inclination towards using premixed insulins in clinical practice until the last decade. However, the advent of insulin glargine 100 U/mL (Gla-100) opened up a new dimension in insulin therapy landscape in India. The data from the last 5 years reveal that Gla-100 has gained more traction among Indian clinical practitioners. ...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Gla-100 Initiation: The When, Why, and How.
Authors: Phadke U, Girish P, Subrahmanyam S, Wagh O, Prajapati A, Kinariwala M, Rastogi A, Paserkar G, Mohan V Abstract Early insulin initiation benefits people with diabetes by inducing a rapid and sustained glycemic control along with preventing the onset of adverse legacy effects early in the disease course. This has an over-arching effect as it could possibly modify the disease course and prevent the development of vascular complications, as has been attested to in landmark studies like the UKPDS and GRACE. Insulin glargine 100 U/mL (Gla-100) has been extensively studied under various scenarios as the initial i...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Basal Insulin Titration: Moving Towards a More Patient-Centric Approach with Gla-100 in India.
Authors: Madhu SV, Neelaveni K, Pitale S, Somani S, Pandey AK, Kalra P, Ceaser R, Mohanasundaram S, Mohan V Abstract Owing to the progressive nature of the disease, patients with type 2 diabetes mellitus (T2DM) eventually require adjustment or titration of insulin doses to achieve the desired glycemic control. Titration inertia, or the inability to dose-titrate, is one of the key barriers to optimized insulin therapy and is common in Asian countries such as India. Simple and effective titration algorithms involving the use of basal insulin, which has the lowest hypoglycemia risk, that can be individualized by physi...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Intensification of Gla-100 with Prandial Insulin: A Stepwise Progression Toward Glycemic Control.
Authors: Wangnoo SK, Damodharan S, Sastry NG, Bhattacharyya S, Selvan C, Mohan B, Sarmah C, Arivazhahan A, Mohan V Abstract The inadequate control of postprandial glucose (PPG) excursions, are linked in some studies with cardiovascular disease. Even though basal insulins, such as insulin glargine 100 U/mL (Gla-100), maintain overall glycemic control, effective PPG control eventually requires intensification of therapy by adding prandial insulins. Compared to conventional basal-bolus or premixed approaches, a stepwise basal-plus or basal-prandial intensification regimen involving the addition of one, two, or three p...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Cardiovascular Safety of Gla-100: Reflections From the ORIGIN and ORIGINALE Trials.
Authors: Goyal G, Shankar P, Jindal S, Ranbir S, Roy Choudhury S, Roy A, Nair T, Roy Choudhury S, Mohan V Abstract Cardiovascular diseases (CVD) risk in people with type 2 diabetes mellitus (T2DM) is two to four folds higher than in individuals without T2DM. Insulin therapy was speculated to be atherogenic- thereby aggravating CVD risk years ago. However, cardiovascular outcome trials (CVOTs) such as the Outcome Reduction with Initial Glargine Intervention (ORIGIN), and its extended follow-up study - ORIGIN and Legacy Effects (ORIGINALE) conclusively established the long-term cardiovascular (CV) safety of basal ins...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

In the Spotlight: Role of Gla-100 in the Glycemic Management of Hospitalized people with diabetes.
Authors: Chatterjee S, Chawla R, Prakash A, Santosh R, Swain J, Jaiswal AA, Bhattacharjee B, Lalan B, Mohan V Abstract Both hyperglycemia and hypoglycemia in hospitalized patients represent a major concern as they are associated with adverse outcomes-including increased rates of infection, longer hospital stay, and even death. Insulin therapy is the mainstay in the management of inpatient hyperglycemia. The traditional approach of sliding scale insulin (SSI) therapy for the temporary management of blood glucose levels in hospitalized patients, has now given way to basal-bolus insulin (BBI) therapy. This is owing to...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Use of Gla-100 in Special Situations.
Authors: John M, Paul TV, Joshi A, Kumar R, Gupta PR, Kumar S, Nahata K, Ravindra BK, Mohan V Abstract Insulin therapy is the cornerstone of diabetes management in people with type 2 diabetes mellitus (T2DM). Therefore, its use is recommended even in special populations and situations such as the elderly, pregnant women, obese individuals, people observing religious fasting, and in the presence of comorbidities such as renal insufficiency, and cancer. Since these special situations predispose to complications such as a high risk of hypoglycemia, patients need constant glucose monitoring and insulin dose adjustments...
Source: Journal of the Association of Physicians of India - November 30, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

COVID 19 and the Liver.
Authors: Shukla A, Mohanka R PMID: 33187029 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Seroprevalence of COVID-19 Amongst Health Care Workers in a Tertiary Care Hospital of a Metropolitan City from India.
Authors: Goenka M, Afzalpurkar S, Goenka U, Das SS, Mukherjee M, Jajodia S, Shah BB, Patil VU, Rodge G, Khan U, Bandyopadhyay S Abstract Background: Seroprevalence studies for COVID-19 evaluate the extent of undetected transmission in a defined community, with special significance among health care workers (HCW) owing to their greater exposure and potential to transmit. Methods: A total of 1122 HCW (approximately 25% of the employees) of a large tertiary care hospital in India were recruited for this cross-sectional study. COVID PCR-positive HCW were excluded. Based on their risk-assessment, participants were g...
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Dermatomyositis during COVID-19 Pandemic (A Case Series): Is there a Cause Effect Relationship?
Authors: Gokhale Y, Patankar A, Holla U, Shilke M, Kalekar L, Karnik ND, Bidichandani K, Baveja S, Joshi A Abstract Viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes, systemic lupus erythematosus (SLE), rheumatoid arthritis and multiple sclerosis. Viral infections have also been considered as a possible trigger for autoimmune disorders like myositis through myositis specific antibodies. Dermatomyositis is an acquired inflammatory myopathy which is relatively rare with incidence of 9.3 per 1 million persons. Usually we come across 1-2 patients of dermato...
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Demographic and Clinical Profile of Dengue Fever in a Tertiary Care Hospital of South India.
Conclusion: Intense monitoring, early detection, and management of complications can prevent mortality in dengue. PMID: 33187032 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Comparative Assessment of Revascularization Versus Drug Management in Coronary Artery Disease (CAD) Associated with Left Ventricular Dysfunction (EF < 40%) - A 12 Month Study with FDG PET and SPECT MPI Analyses.
Comparative Assessment of Revascularization Versus Drug Management in Coronary Artery Disease (CAD) Associated with Left Ventricular Dysfunction (EF
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Identification of Missing Probes in rpoB gene in Rifampicin Resistant PTB and EPTB Cases Using Xpert MTB/RIF Assay in Sirmaur, Himachal Pradesh.
Conclusion: Drug resistance in the MTBC is mainly conferred through point mutations in specific gene targets in the bacterial genome. Molecular assays like Genexpert gives rapid diagnosis and Rifampicin resistance. This study helps to provide baseline data of mutations with in the 81 bp of rpoB gene and stresses the need to further evaluate the mutation patterns in this part of the country. PMID: 33187034 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Cardiac Involvement in Vasculotoxic and Neurotoxic Snakebite - A not so Uncommon Complication.
Conclusion: Cardiac toxicity is a well defined complication of poisonous snake bite and incidence is more frequent than previously thought. Both vasculotoxic and neurotoxic snake bites are associated with cardiac toxicity and is not associated with increase in mortality. PMID: 33187035 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Echocardiographic Pattern of Congenital Heart Diseases in Adolescent and Adult population of Western Rajasthan.
Conclusion: Prevalence of CHD in study cohort of age more than 12 years in Western Rajasthan, India was 7.7 per 1000 study population. Profile of CHDs in the present study was similar to that in published literature. We propose to do larger and targeted studies in this age group because many CHDs will become inoperable or even if operated will leave some or other cardiac dysfunction beyond adolescence. PMID: 33187036 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Current Clinical Evidence of Trimetazidine in the Management of Heart Disease in Patients with Diabetes.
Authors: Mahajan S, Mahajan AU Abstract Diabetes Mellitus (DM) is a global heath burden and the leading cause for cardiovascular (CV) disease. The differential presentation of CV disease in DM is related to the metabolic derangements leading to deterioration of myocardial cell function and its serious consequences. Therefore, there is a need for early and effective treatment intervention for this myocardial cell metabolic dysfunction. DM and myocardial ischemia (MI) share a common metabolic dysregulation mediated via increased fatty acid oxidation that makes the diabetic heart susceptible to myocardial ischemia and...
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Erectile Dysfunction: A Review on Prevalence, Perceptions, Diagnosis and Management in India.
Authors: Debasis B, Ann SP, Bhimrao FS, Sonia M Abstract Erectile dysfunction (ED) is defined as the inability to achieve or maintain penile erection sufficient to permit satisfactory sexual activity. The prevalence increases with age. Basic and clinical research is identifying the neurovascular and humoral control of the mechanisms. The initial evaluation should differentiate erectile dysfunction from premature ejaculation and loss of libido. Myocardial insufficiency, hypogonadism and peripheral neuropathy should be looked for. Initial laboratory investigations should be restricted to identifying previously undete...
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Palliative and End of Life Care in India - Current Scenario and the Way Forward.
Authors: Bag S, Mohanty S, Deep N, Salins N, Bag S Abstract India, being home to one -sixth of the world's population has a huge burden of suffering from life limiting diseases. It is estimated that in India the total no. of people who need palliative care (PC)is likely to be 5.4 million people a year. Though PC was introduced nearly 30 years ago, it is still in its infancy with less than 1% of patients having access to PC. India ranks at the bottom of the Quality Of Death Index in overall score. Obstacles are too many and not only include factors like population density, poverty, geographical density, restrictive ...
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Coronavirus Disease-19 (COVID-19) and Heart Failure: Current Perspective.
This article describes the mechanisms, clinical presentations and management of heart failure caused by COVID-19 infection. PMID: 33187040 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

To Side the Patients or their Family Members: A Doctor's Eternal Dilemma.
Authors: Naik BS Abstract The family members of the patient play a significant role in the medical management. However, physician's primary responsibility is towards his patient and not to heed to the requests of the family members. All the medical professionals should be well equipped to face multiple dilemmas in their carrier. PMID: 33187041 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

A Rare Neurotoxic Red-tailed-skink Bite.
Authors: Kumari M, Kumar R, Kumar R, Abinaya PMID: 33187042 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Acquired Haemophilia.
Authors: Kannan K, Girija T, Gurusamy SK, Dwarkanathan C PMID: 33187043 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Isolated Oculomotor Nerve Palsy - A Rare Initial Manifestation of Tuberculous Meningitis.
Authors: Singh AK, Agarwal P, Baiswar R Abstract Tuberculous meningitis (TBM) is a sub-acute / chronic meningitis known for its diverse manifestations which may lead to delayed diagnosis. An isolated oculomotor nerve palsy as an initial presentation of TB meningitis is quite rare. One such case has presented here; A 18 year female presented to us with ptosis of the left eye. Complete neurological examination revealed it to be a case of isolated 3rd cranial nerve palsy. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) brain revealed no significant abnormality. Cerebrospinal fluid (CSF) analysis was done...
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Right Atrial Extension of a Giant Retroperitoneal Leiomyosarcoma.
We report a rare case of a young male with giant retroperitoneal leiyomyosarcoma which extended into the right atrium. PMID: 33187045 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Fever with Rash: A Clinical Dilemma.
We present herewith a case of a young man with acute febrile illness and rash which raised doubts with regards to the possible etiological diagnosis and necessitated detailed work up which revealed a diagnosis of COVID-19. The case is being highlighted as often the history and clinical presentation may seem to be obvious but an atypical uncommon presentation which in this case was a maculopapular rash may not fit the picture of a single etiological diagnosis according to the known medical literature. PMID: 33187046 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - November 17, 2020 Category: General Medicine Tags: J Assoc Physicians India Source Type: research