Swallowing Dysfunction after Acute Stroke: The Incidence, Predictors and Outcome
CONCLUSION: Swallowing dysfunction should be checked in all cases of strokes, including unilateral hemispheric strokes and in fully conscious patients. Swallowing improves with time, but the patient may require feeding assistance in an acute setting. Dysphagia is more common in strokes with higher NIHSS, involving more brain parenchyma and posterior circulation strokes.PMID:37651239 | DOI:10.59556/japi.71.0301 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Charulata Londhe Aashish Agrawal Sangeeta Pednekar Dharmendra Pandey Mohammed Fasahatulla Khan Source Type: research

Efficacy and Safety of Directly Acting Antivirals in Patients with Hepatitis C Infection on Hemodialysis
CONCLUSION: Sofosbuvir combination therapy offers an excellent response in dialysis patients irrespective of the genotype and presence of cirrhosis with minimal monitoring as in non-chronic kidney disease (CKD) patients.PMID:37651240 | DOI:10.59556/japi.71.0302 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Manisha Sahay None Priyashree Kiranmai Ismal K Anuradha Jyoti Lakshmi Source Type: research

Clinical Profile of Adult Hemophilia Patients with Special Reference to FISH and WFHPE Score: An Observational Cross-sectional Study
J Assoc Physicians India. 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0286.ABSTRACTBACKGROUND AND OBJECTIVES: Hemophilia is an X-linked recessive inherited disease affecting the coagulation pathway due to congenital deficiencies in either factor VIII (hemophilia A) or factor IX (hemophilia B). The clinical assessment of a patient's functional ability and the state of joint conditions is carried out by the clinicians by administering questionnaires namely the Gilbert or the World Federation of Hemophilia Physical Examination (WFH-PE) score for joint condition and Functional Independence Score in Hemophilia (FISH) for joint ...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Minal Shastri Renuka Vasava Vaibhavi Pancholi Vaishnavi M Rathod Gaurav Mehta Gayatri Laha Darshankumar Manubhai Raval Source Type: research

Knowledge Dissemination for elimination Role of Academic Institutions in Eliminating Viral Hepatitis
CONCLUSION: The study observed significant improvement in knowledge among the participants following a low-cost 1-day training in webinar mode. Such training programs can be upscaled and help in educating the general public on hepatitis.PMID:37651242 | DOI:10.59556/japi.71.0279 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Tushar Prabhakar Kanica Kaushal Source Type: research

Nonsmoker COPD represents a clinically Distinct Phenotype: A Prospective Observational Study
CONCLUSION: Compared to smokers, COPD in never-smokers presents at a younger age, with a longer duration of dyspnea and higher eosinophil count. Biomass exposure is one of the major contributors to etiologies for COPD in nonsmokers.PMID:37651243 | DOI:10.59556/japi.71.0285 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Richa Rani Pawan K Singh Manjunath B Govindagoudar Tarana Gupta None Parul Dhruva Chaudhry Source Type: research

The Role of Monocyte to High-density Lipoprotein Cholesterol Ratio in Predicting the Severity of Acute Ischemic Stroke and its Association with the NIHSS
CONCLUSION: In our study, the MHR shows an increased value in patients with AIS, and a linear correlation is found with the NIHSS score. Thus, the method is a pocket-friendly, easily available, and simple-to-use novel inflammatory marker that may predict the severity of a disease.PMID:37651244 | DOI:10.59556/japi.71.0321 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Deepti Sharma Sreedev Aravind Sony Joseph Narendra Fagera Gopikrishnan Rajagopalan Source Type: research

Diabetes in India's North East Study: Prevailing Insulin Usage and Insulin Injection Practices amongst Type 2 Diabetes Mellitus Patients
CONCLUSION: This audit depicts important attributes of current injection practices amongst T2DM patients on insulin and suggests the possible benefits of adopting correct practices for avoiding complications such as LH and hypoglycemia.PMID:37651245 | DOI:10.59556/japi.71.0323 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Manash P Baruah Sonali B Bhuyan Sanjay Kalra Mangesh H Tiwaskar Source Type: research

ADVANCE to ADVANCE-ON: Unfolding the "Legacy Story" in Diabetes
J Assoc Physicians India. 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0319.ABSTRACTType 2 diabetes mellitus (T2DM) is a progressive disease. The importance of early intensive glucose lowering in preventing vascular complications in diabetes is well established. Sulfonylureas (SU) is recommended by most guidelines and widely used for the management of T2DM. However, there has been ambiguity around the long-term benefits with regard to microvascular and macrovascular outcomes with SUs. The United Kingdom Prospective Diabetes Study (UKPDS) provided evidence of sustained cardiovascular (CV) and microvascular benefits of previo...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Sanjay Kalra Source Type: research

Over 30 Years of Omeprazole
CONCLUSION: Omeprazole is the prototypical drug in the management of APDs and has withstood the test of time. After 3 decades, omeprazole remains the drug of choice in managing APD.PMID:37651247 | DOI:10.59556/japi.71.0322 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Praveen Sharma Source Type: research

Expert Recommendations on Optimizing the Diagnosis and Management of Gastroesophageal Reflux Disease Associated with Comorbidities in the Indian Population
J Assoc Physicians India. 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0269.ABSTRACTGastroesophageal reflux disease (GERD) is among the most prevalent gastrointestinal (GI) disorders. It is known to often coexist with other chronic diseases such as asthma, chronic obstructive pulmonary disease (COPD), obesity, diabetes mellitus (DM), and hypertension. Upper endoscopy, esophageal manometry, and impedance-pH monitoring are a few invasive diagnostic options that are reserved for selected GERD patients. Symptom assessment by using questionnaires, such as the frequency scale for the symptoms of GERD (FSSG), is simple, convenient...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Harjit Dumra Rajesh Sainani Nitesh Pratap Bhanu P Singh Indranil Halder Jayesh Shah Mehul Thakkar Mohan Kumar V Nitin Abhyankar P P Bose Rutul Gokalani Vikas Aggarwal Devasahayam J Christopher Source Type: research

A Historical Perspective on Chronic Obstructive Pulmonary Disease: From Past to Present
J Assoc Physicians India. 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0251.ABSTRACTRené-Théophile-Hyacinthe Laennec in his book "Treatise of the Diseases of the Chest" discussed the emphysema in 1821. Chronic obstructive pulmonary disease (COPD) has been around for at least 202 years, from 1821 to 2023 (but the disease itself is much older than that). It is believed that William Briscoe first used the term COPD in June 1965, at the 9th Aspen Emphysema Conference. COPD was first defined by the CIBA guest symposium in 1959 and the American Thoracic Society Committee on Diagnostic Standards in 1962; recent definition of COP...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Surya Kant Ajay Kumar Verma Anuj Kumar Pandey Source Type: research

Alternate Biochemical Markers in Organophosphate Poisoning
J Assoc Physicians India. 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0325.ABSTRACTIn India, organophosphates are the most widely used pesticides for suicide by poisoning. Early recognition of the diagnosis and its severity will help in achieving a better outcome. In poisoning by organophosphorus compounds, serum acetylcholinesterase (AChE) and pseudocholinesterase are currently widely accepted as biochemical markers for estimating the severity. A wide array of alternate, cheap, and easily available markers are explored in this review and using a combination of these markers may be better in terms of early identification o...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Austin J Mangaly Chandni Radhakrishnan Source Type: research

Simplifying Type 2 DM Care with Linagliptin: A Position Paper
CONCLUSION: Linagliptin therapy is simplifying the management of T2DM with good efficacy and its use across a wide range of patients without any dose modification.PMID:37651251 | DOI:10.59556/japi.71.0324 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Ambrish Mithal Ambady Ramachandran Arpandev Bhattacharyya Manoj Chadha Mala Dharmalingam Anirban Majumder Debmalya Sanyal Source Type: research

Show Me the Money: Finance for the Physician
J Assoc Physicians India. 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0300.NO ABSTRACTPMID:37651252 | DOI:10.59556/japi.71.0300 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Rohit Bansal Source Type: research

Brucellosis in a Sickle Cell Patient with Hyposplenia
J Assoc Physicians India. 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0308.ABSTRACTSickle cell disease patients are prone to infection and overwhelming sepsis because an immunedeficient state arises from asplenia (autosplenectomy/surgical splenectomy) and functional hyposplenism. The common pathogen encountered in sepsis with asplenic/hyposplenism patients is encapsulated organism, gram-negative bacilli, but in developing countries like India, there are many possibilities of infection by an uncommon organism that make it difficult to diagnose. Here, we have described a case of sickle cell disease presented with persistent ...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Jhasaketan Meher Nithin M S Sunil K Behera Source Type: research