Arteriovenous fistulas in hemodialysis: factors of success and the role of nephrologists.
Authors: Franco RP Abstract PMID: 30625232 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - January 11, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Metabolic and volume status evaluation of hemodialysis patients with and without residual renal function in the long interdialytic interval.
Authors: Almeida LLS, Sette LHBC, Fonseca FLA, Bezerra LSVDS, Oliveira Júnior FH, Bérgamo RR Abstract INTRODUCTION: It is unclear whether residual renal function (RRF) in dialysis patients can attenuate the metabolic impact of the long 68-hour interdialytic interval, in which water, acid, and electrolyte accumulation occurs. OBJECTIVE: to evaluate serum electrolyte levels, water balance, and acid-base status in dialytic patients with and without RRF over the long interdialytic interval (LII). METHODOLOGY: this was a single-center, cross-sectional, and analytical study that compared patients wi...
Source: Jornal Brasileiro de Nefrologia - January 10, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Bone biopsy in nephrology practice.
Authors: Barreto FC, Costa CRVD, Reis LMD, Custódio MR Abstract Renal osteodystrophy (ROD), a group of metabolic bone diseases secondary to chronic kidney disease (CKD), still represents a great challenge to nephrologists. Its management is tailored by the type of bone lesion - of high or low turnover - that cannot be accurately predicted by serum biomarkers of bone remodeling available in daily clinical practice, mainly parathyroid hormone (PTH) and alkaline phosphatase (AP). In view of this limitation, bone biopsy followed by bone quantitative histomorphometry, the gold-standard method for the diagnosis of...
Source: Jornal Brasileiro de Nefrologia - December 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Resistant and refractory hypertension: two sides of the same disease?
In conclusion, both RH and RfH constitute challenges in clinical practice and should be addressed as distinct clinical entities by trained professionals who are capable to identify comorbidities and provide specific, diversified, and individualized treatment. PMID: 30525180 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - December 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Chronic kidney disease patients who smoke have higher serum phosphorus.
CONCLUSION: Smoking confers a higher cardiovascular risk to CKD patients under conservative treatment as it is associated with higher levels of P. Further studies are needed to confirm and better elucidate this finding. PMID: 30534856 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - December 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Cecum perforation associated with a calcium polystyrene sulfonate bezoar - a rare entity.
Authors: Fiel DC, Santos I, Santos JE, Vicente R, Ribeiro S, Silva A, Malvar B, Pires C Abstract Hyperkalemia is one of the most common electrolyte disorders, responsible for a high number of adverse outcomes, including life-threatening arrhythmias. Potassium binders are largely prescribed drugs used for hyperkalemia treatment but unfortunately, there are many adverse events associated with its use, mostly gastrointestinal. Identification of patients at highest risk for the serious complications associated with the current potassium binders, such as colon necrosis and perforation, could prevent fatal outcomes. The ...
Source: Jornal Brasileiro de Nefrologia - December 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Differences in phosphatemia and frequency of consumption of dietary sources of phosphorus in hemodialysis patients in southern and northern Brazil.
Authors: Nerbass FB, Canzi ER, Araujo RDA, Corrêa D, Santos RGD, Vieira MA, Morais JG Abstract INTRODUCTION: Hyperphosphatemia is associated with unfavorable outcomes, and the percentage of patients presenting with this condition in hemodialysis (HD) in kidney foundation units in the state of Santa Catarina (SC) is historically higher than that of patients in the state of Tocantins (TO). OBJECTIVE: To assess the frequency of consumption of the main dietary sources of phosphorus and to compare them between the two states. METHODOLOGY: A cross-sectional study was carried out involving 123 patients, 66 o...
Source: Jornal Brasileiro de Nefrologia - December 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Pediatric lupus nephritis.
Authors: Pinheiro SVB, Dias RF, Fabiano RCG, Araujo SA, Silva ACSE Abstract Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options. PMID:...
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Acute Kidney Injury Epidemiology in pediatrics.
Authors: Cleto-Yamane TL, Gomes CLR, Suassuna JHR, Nogueira PK Abstract We performed a search in the MEDLINE database using the MeSH term: "Acute Kidney Injury", selecting the subtopic "Epidemiology", and applying age and year of publication filters. We also searched for the terms: "acute renal failure" and "epidemiology" "acute tubular necrosis" and "epidemiology" in the title and summary fields with the same filters. In a second search, we searched in the LILACS database, with the terms: "acute renal injury", or "acute renal failure" ...
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Multidisciplinary approach for patients with nephropathic cystinosis: model for care in a rare and chronic renal disease.
Authors: Vaisbich MH, Satiro CAF, Roz D, Nunes DAD, Messa ACHL, Lanetzki C, Ferreira JCOA Abstract Care for patients with chronic and rare diseases is complex, especially considering the lack of knowledge about the disease, which makes early and precise diagnosis difficult, as well as the need for specific tests, sometimes of high complexity and cost. Added to these factors are difficulties in obtaining adequate treatment when available, in raising patient and family awareness about the disease and treatment compliance. Nephropathic cystinosis is among these diseases. After more than 20 years as a care center for t...
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Parathyroidectomy in the treatment of BMD-DRC Brazil: many limitations, but still fundamental.
Authors: Carmo LPF PMID: 30465593 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Erratum.
Authors: Abstract [This corrects the article doi: 10.1590/2175-8239-JBN-2018-00030003] [This corrects the article doi: 10.1590/2175-8239-JBN-2018-00030002][This corrects the article doi: 10.1590/1678-4685-JBN-2018-00020001]. PMID: 30465594 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Intradialytic resistance training: an effective and easy-to-execute strategy.
CONCLUSION: IRT led to significant increases in PC and higher scores in all domains of QoL. Important adverse events were not observed during intradialytic resistance training. PMID: 30421780 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Pathogenesis, histopathologic findings and treatment modalities of lipoprotein glomerulopathy: A review.
Authors: Cambruzzi E, Pêgas KL Abstract Lipoprotein glomerulopathy (LPG) is an uncommon cause of nephrotic syndrome and/or kidney failure. At microscopy, LPG is characterized by the presence of lipoprotein thrombi in dilated glomerular capillaries due to different ApoE mutations. ApoE gene is located on chromosome 19q13.2, and can be identified in almost all serum lipoproteins. ApoE works as a protective factor in atherosclerosis due its interaction with receptor-mediated lipoprotein clearance and cholesterol receptor. Most common polymorphisms include ApoE2/2, ApoE3/2, ApoE3/3, ApoE4/2, ApoE4/3, and ApoE4/4....
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Association between religiosity and happiness in patients with chronic kidney disease on hemodialysis.
CONCLUSIONS: Patients on hemodialysis showed high levels of R/S, which correlated with higher happiness levels. Clinical and sociodemographic variables were not correlated with patients' happiness. Psychosocial variables such as R/S and SC are potential key targets for interventions to promote better survival quality among CKD patients. PMID: 30421782 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Micro RNA 146a-5p expression in Kidney transplant recipients with delayed graft function.
CONCLUSION: We conclude that miR-146a-5p expression has a distinct pattern in the renal tissue and perhaps in the peripheral blood in the setting of DGF. Further refinements and strategies for studies should be developed in the field of non-invasive molecular diagnosis of kidney graft dysfunction. PMID: 30421783 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Hypertension in patients on dialysis: diagnosis, mechanisms, and management.
Authors: Bucharles SGE, Wallbach KKS, Moraes TP, Pecoits-Filho R Abstract Hypertension (blood pressure> 140/90 mm Hg) is very common in patients undergoing regular dialysis, with a prevalence of 70-80%, and only the minority has adequate blood pressure (BP) control. In contrast to the unclear association of predialytic BP recordings with cardiovascular mortality, prospective studies showed that interdialytic BP, recorded as home BP or by ambulatory blood pressure monitoring in hemodialysis patients, associates more closely with mortality and cardiovascular events. Although BP is measured frequently in the dialys...
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Carotid artery thickness in obese patients with chronic renal failure.
Authors: Santos VMD Abstract PMID: 30353908 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 26, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

The future is coming: promising perspectives regarding the use of machine learning in renal transplantation.
CONCLUSION: The way we deal with storage data in electronic health records will radically change in the coming years and machine learning will be part of clinical daily routine, whether to predict clinical outcomes or suggest diagnosis based on institutional experience. PMID: 30353909 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 26, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Crisis management and the dilemma of rationing strategies in healthcare organizations.
Authors: Moura-Neto JA, Moura AF, Moura JA Abstract PMID: 30353910 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 26, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Hemophagocytic lymphohistiocytosis, a rare condition in renal transplant - a case report.
We report a case of a 50-year-old renal transplant female admitted with fever and malaise 3 months post-transplant and presenting anemia, fever, hypertriglyceridemia, high levels of serum ferritin, and positive CMV antigenemia. Urine was positive for decoy cells and BKV-DNA. Graft biopsy showed CMV nephritis. Both blood and urine cultures where positive for E. coli. Hemophagocytosis was confirmed by bone marrow aspiration. Immunosuppression was reduced, and the patient received high-dose intravenous immunoglobulin and dexamethasone, with complete response after 3 weeks. We highlight the importance of early diagnosis and pr...
Source: Jornal Brasileiro de Nefrologia - October 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Albuminuria and glomerular filtration rate in obese children and adolescents.
CONCLUSION: Albuminuria, although frequent in children and adolescents with obesity, was not associated with other morbidities and the glomerular filtration rate in these patients. PMID: 30328467 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Long-term effects of delayed graft function duration on function and survival of deceased donor kidney transplants.
Authors: Helfer MS, Pompeo JC, Costa ORS, Vicari AR, Ribeiro AR, Manfro RC Abstract INTRODUCTION: Delayed graft function (DGF) is a frequent complication after deceased donor kidney transplantation with an impact on the prognosis of the transplant. Despite this, long-term impact of DGF on graft function after deceased donor kidney transplantation has not been properly evaluated. OBJECTIVE: The main objective of this study was to evaluate risk factors for DGF and the impact of its occurrence and length on graft survival and function. METHODS: A retrospective cohort study was performed in 517 kidney transplan...
Source: Jornal Brasileiro de Nefrologia - October 11, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Translumbar hemodialysis long-term catheters: an alternative for vascular access failure.
CONCLUSION: TLDC is an option for patients with VA failure, improving survival and acting as a bridge for renal transplantation. PMID: 30281060 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Successful multiple-exchange peritoneal dialysis in a patient with severe hematological toxicity by methotrexate: case report and literature review.
We present the case of a 68-year-old man with chronic, end-stage renal disease associated with ANCA vasculitis, under treatment with peritoneal dialysis, who received the medication at a low dose, indicated by disease activity, which presented as a complication with severe pancytopenia with mucositis that improved with support measures and multiple-exchange peritoneal dialysis. We reviewed 20 cases published to date of pancytopenia associated with methotrexate in patients on dialysis and found high morbidity and mortality, which is why its use in this type of patient is not recommended. However, when this complication occu...
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Pathophysiological aspects of nephropathy caused by non-steroidal anti-inflammatory drugs.
Authors: Lucas GNC, Leitão ACC, Alencar RL, Xavier RMF, Daher EF, Silva Junior GBD Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used medications associated with nephrotoxicity, especially when used chronically. Factors such as advanced age and comorbidities, which in themselves already lead to a decrease in glomerular filtration rate, increase the risk of NSAID-related nephrotoxicity. The main mechanism of NSAID action is cyclooxygenase (COX) enzyme inhibition, interfering on arachidonic acid conversion into E2 prostaglandins E2, prostacyclins and thromboxanes. Within the kidneys, pro...
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Reversible posterior encephalopathy syndrome in a 10-year-old child.
CONCLUSION: PRES is associated with acute hypertension. Early diagnosis and proper management may determine a better prognosis and minimize the severity of the clinical course. PMID: 30281063 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Thumb adductor muscle thickness used in the nutritional assessment of chronic kidney disease patients under conservative treatment.
Authors: Pereira PML, Soares ÍT, Bastos MG, Cândido APC Abstract INTRODUCTION: Evaluate the association between the thumb adductor muscle thickness and the patient's nutritional status, and propose cutoff points for muscle mass depletion in elderly patients with chronic kidney disease (CKD) under conservative treatment. Epidemiological and cross-sectional study, including patients with CKD stages 3 to 5, older than 60 years. Socioeconomic, clinical, physical activity and anthropometric data was obtained. TAMT was described and compared according to CKD stage, socioeconomic data, physical activity, nutr...
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

IgA nephropathy in Salvador, Brazil: a more aggressive disease?
Authors: Barros RT PMID: 30281065 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

The effect of music therapy on hemodialysis patients' quality of life and depression symptoms.
This study evaluated the effect of music therapy on QOL and depressive symptoms in hemodialysis patients. METHOD: This was a music therapy intervention study in which 23 patients were evaluated regarding QOL and depression symptoms at two distinct stages - before and after the intervention. Eight sessions of music therapy were conducted, with two weekly sessions and an average duration of 75 minutes. The intervention was conducted by the music therapist herself, using specific music therapy techniques, besides voice and guitar to conduct harmonic and rhythmic support for the groups' sound-music production. RESULTS:...
Source: Jornal Brasileiro de Nefrologia - September 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Renal histological findings in a patient with acute renal injury associated with purpura fulminans: a case report.
CONCLUSION: When thrombotic and hemorrhagic phenomena overlap, obtaining a renal biopsy can be difficult. However, in the presented case, the biopsy allowed the exclusion of AKI caused by TMA, presenting for the first time, histological findings compatible with PF. PMID: 30222177 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - September 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Cognition and renal function: findings from a Brazilian population.
Authors: Chaiben VBO, Silveira TBD, Guedes MH, Fernandes JPA, Ferreira JHF, Beltrão J, Leal GF, Erbano LHO, Bosch NL, Pecoits Filho R, Moraes TP, Baena CP Abstract INTRODUCTION: The prevalence of chronic kidney disease (CKD) is increasing, with a potential impact in the risk of acceleration of dementia. The potential association between glomerular filtration rate (eGFR) and cognitive performance was scarcely studied. The aim of this study was to evaluate cognitive performance levels across different degrees of kidney function. METHODS: We analyzed 240 outpatients in a nephrology service, classified accor...
Source: Jornal Brasileiro de Nefrologia - September 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Salvage of thrombosed arteriovenous fistulae of patients on hemodialysis: report on the experience of a Brazilian center.
CONCLUSION: The majority of thrombosed accesses can be successfully treated, maintaining its long-term patency. The need of repeated intervention is frequent. PMID: 30207374 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - September 14, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Reflections on End-of-Life Dialysis.
Authors: Tzanno-Martins C PMID: 30199557 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - September 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

A teenage patient with autosomal recessive polycystic kidney disease, a splenorenal shunt, and congenital hepatic fibrosis: a case report.
Authors: Scarioti VD, Oliveira LT, Mattiello AC, Gomes NDS Abstract A 16-year-old female patient previously diagnosed with autosomal recessive polycystic kidney disease (ARPKD) presented with acute bilateral pneumonia, upper gastrointestinal bleeding caused by ruptured esophageal varices, ascites, and lower limb edema. She required intensive care and an endoscopic procedure to treat the gastrointestinal bleeding. The analysis of the differential diagnosis for chronic liver disease indicated she had a spontaneous splenorenal shunt. Ultrasound-guided biopsy revealed the patient had cirrhosis, as characteristically se...
Source: Jornal Brasileiro de Nefrologia - September 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Oral manifestations of renal tubular acidosis associated with secondary rickets: case report.
This report describes the oral manifestations of renal tubular acidosis (RTA) associated with secondary rickets and discusses the biological plausibility of these findings. The characteristic electrolyte changes during RTA or genetic mutations that trigger RTA may be responsible for impaired amelogenesis, dental malocclusion, impacted teeth, and absent lamina dura. This report reinforces the possibility of an association between RTA and the oral manifestations described. PMID: 30199559 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - September 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Anca-associated crescentic glomerulonephritis in a child with isolated renal involvement.
We report a case of a 7-year-old girl who presented with malaise and mildly elevated creatinine diagnosed as ANCA-associated pauci-immune crescentic glomerulonephritis with crescents in 20 of 25 glomeruli (80%). Of these 20 crescents, 12 were cellular, 4 fibrocellular, and 4 globally sclerotic. She did not have purpura, arthritis, or systemic symptoms and she responded well to initial immunosuppressive treatment despite relatively severe histopathology. The patient was given three pulses of intravenous methylprednisolone (30 mg/kg on alternate days) initially and continued with cyclophosphamide (CYC; 2 mg/kg per day) orall...
Source: Jornal Brasileiro de Nefrologia - September 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Pure red cell aplasia and anti-erythropoietin antibodies in patients on hemodialysis: a report of two cases and a literature review.
CONCLUSION: PRCA is a rare condition among patients on dialysis treated with rhEPO and should be considered as a possible cause of refractory anemia. Treating patients with PRCA may be challenging, since the specific management and diagnostic procedures needed in this condition are not always readily available. PMID: 30160771 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - September 1, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Acute renal failure by rapidly progressive glomerulonephritis with IgA deposition in a patient concomitantly diagnosed with multibacillary Hansen's disease: a case report.
Authors: Parente YDM, Castro AL, Araújo FB, Teixeira AC, Lima ÍC, Daher EF Abstract Rapidly progressive glomerulonephritis (RPGN) is a renal disease with an extensive differential diagnosis. This paper reports the case of a 55-year-old female patient diagnosed with Hansen's disease with acute progressive renal impairment after developing lower limb pyoderma. The association between Hansen's and kidney disease has been well documented, with glomerulonephritis (GN) ranked as the most common form of renal involvement. Post-infectious glomerulonephritis (PIGN) in adults has been associated with a number o...
Source: Jornal Brasileiro de Nefrologia - September 1, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

An atypical presentation of a severe and massive atheroembolic disease.
Authors: Falcão LP, Fernandes S, Costa AC, Teixeira C, Raimundo M, Silva S, Miranda M, Almeida E Abstract Atheroembolic renal disease (AERD) is a kidney manifestation of atherosclerosis as a systemic disease. AERD is defined as a renal impairment secondary to embolization of cholesterol crystals with consequent occlusion of renal vascularization. The current case report describes one patient with multiple risk factors but without any inciting event history who presents a very atypical clinical course of a severe and massive atheroembolic disease that developed spontaneously and silently. PMID: 30129967 [...
Source: Jornal Brasileiro de Nefrologia - August 23, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

TpTe and TpTe/QT: novel markers to predict sudden cardiac death in ESRD?
CONCLUSIONS: In ESRD patients on hemodialysis, prolonged TpTe or TpTe/QT was not associated with a significant increase in SCD or all-cause mortality. PMID: 30118535 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - August 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Inflammation and kidney injury attenuated by prior intake of Brazil nuts in the process of ischemia and reperfusion.
CONCLUSION: In experimental IR, the damage can be minimized with a prior low-dose intake of BN, improving inflammation, injury, and cell death. PMID: 30118536 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - August 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

The role of C-peptide in the attenuation of outcomes of diabetic kidney disease: a systematic review and meta-analysis.
CONCLUSION: The results of the studies included in the systematic review diverged. However, the meta-analysis showed that the animals given C-peptide had lower glomerular volumes and lower urine potassium levels. PMID: 30106427 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - August 16, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Perioperative factors associated with delayed graft function in renal transplant patients.
CONCLUSIONS: Combined anesthesia technique, dialysis for more than 60 months, basiliximab, and cold ischemia time> 12 hours are risk factor for DGF, while liberal fluid regimens and kidneys from living donors are protective factors. PMID: 30106428 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - August 16, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

The specific impact of uremic toxins upon cognitive domains: a review.
Authors: Franco ÁO, Starosta RT, Roriz-Cruz M Abstract One of the mechanisms proposed for chronic kidney disease (CKD)-related cognitive impairment is the accumulation of uremic toxins due to the deterioration of the renal clearance function. Cognition can be categorized into five major domains according to its information processing functions: memory, attention, language, visual-spatial, and executive. We performed a review using the terms 'uric acid', 'indoxyl sulfate', 'p-cresyl sulfate', 'homocysteine', 'interleukins' and 'parathyroid hormone'. These are the compounds that were found to be strongly assoc...
Source: Jornal Brasileiro de Nefrologia - August 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

ANCA associated vasculitis: experience of a tertiary care referral center.
Authors: Chaudhry R, Bilal A, Austin A, Mehta S, Salman L, Foulke L, Feustel P, Zuckerman R, Asif A Abstract BACKGROUND AND OBJECTIVES: Anti-neutrophil cytoplasmic autoantibodies (ANCA) associated vasculitis is a small vessel vasculitis with insufficient epidemiologic estimates in the United States. We aimed to determine demographic and clinical features of ANCA associated vasculitis patients presenting to a large tertiary care referral center in Upstate New York. Design, setting, participants, and measurements: A retrospective analysis of cases with pauci-immune GN on renal biopsy and clinical diagnosis of ANCA va...
Source: Jornal Brasileiro de Nefrologia - August 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

The impact of dialysis on critically ill elderly patients with acute kidney injury: an analysis by propensity score matching.
CONCLUSIONS: The data suggested that dialysis did not seem to impact the death rates of critically ill patients with AKI aged 70+ years. PMID: 30080913 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - August 7, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Evaluation of variables associated with the patency of arteriovenous fistulas for hemodialysis created by a nephrologist.
CONCLUSION: Hemoglobin level in the recommended range has a favorable impact on late AVF patency and elevated blood pressure during surgery on the lower number of vascular accesses per patient. The high success rate indicates that it can be placed by trained nephrologists. PMID: 30080914 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - August 7, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Cerebral Venous Sinus Thrombosis in a Child with Idiopathic Nephrotic Syndrome: a case report.
This report describes the case of a 5-year-old girl with NS for the first time presenting with severe hypoalbuminemia (
Source: Jornal Brasileiro de Nefrologia - August 7, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Effectiveness of the monitoring program for ensuring the quality of water treated for dialysis in the state of S ão Paulo.
CONCLUSION: The design adopted in the state monitoring program is highly effective based on new collections after the joint actions of the Sanitary Surveillance System and the State Dialysis Services. PMID: 30080916 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - August 7, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research