Brazilian chronic dialysis survey 2017.
CONCLUSION: The absolute number of patients and rates of incidence and prevalence on dialysis continued to increase; the mortality rate tended to rise. There were obvious regional and state discrepancies in these rates. PMID: 30968930 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 12, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Differences in quality of life and cognition between the elderly and the very elderly hemodialysis patients.
CONCLUSION: Elderly patients on chronic hemodialysis have a high prevalence of cognitive deficits, especially the very elderly, but this group does not have a worse quality of life, except for functional capacity. PMID: 30897190 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - March 23, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Refractory ascites and graft dysfunction in early renal transplantation.
Discussion: Incomplete septal cirrhosis is an uncommon cause of non-cirrhotic portal hypertension. Its definition is not well known, morphological and pathophysiological. We have not found published cases of post-RT ascites secondary to this pathology, described as possibly associated with drugs, immune alterations, infections, hypercoagulability and genetic predisposition. PMID: 30897191 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - March 23, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Zinc alpha 2 glycoprotein as an early biomarker of diabetic nephropathy in patients with type 2 diabetes mellitus.
CONCLUSION: These findings suggest that urine and serum ZAG might be useful as early biomarkers for detection of DN in T2DM patients, detectable earlier than microalbuminuria. PMID: 30897192 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - March 23, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study.
Authors: Fernandes S, Teixeira C, Falcão LP, Costa AC, Raimundo M, Silva S, Cardoso J, Almeida E Abstract One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no circulating ANCAs, and this subgroup has been known as the ANCA-negative pauci-immune CrGN. RPGN can be associated with systemic diseases, but there are only few case reports describing the association with mixed...
Source: Jornal Brasileiro de Nefrologia - March 23, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

2019 World Kidney Day Editorial - burden, access, and disparities in kidney disease.
Authors: Crews DC, Bello AK, Saadi G Abstract Kidney disease is a global public health problem, affecting over 750 million persons worldwide. The burden of kidney disease varies substantially across the world, as does its detection and treatment. In many settings, rates of kidney disease and the provision of its care are defined by socio-economic, cultural, and political factors leading to significant disparities. World Kidney Day 2019 offers an opportunity to raise awareness of kidney disease and highlight disparities in its burden and current state of global capacity for prevention and management. Here, we highli...
Source: Jornal Brasileiro de Nefrologia - March 15, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Early detection of chronic renal disease: coordinated work between primary and specialized care in an ambulatory renal network of Peru.
CONCLUSIONS: One of every four patients are diagnosed with CKD, and the simultaneous diagnosis of DM and HBP and old age are the most important factors. PMID: 30855635 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - March 12, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Burden, depression and anxiety in primary caregivers of children and adolescents in renal replacement therapy.
CONCLUSIONS: Caring for a child with CKD is an intense experience, with negative consequences, due to uncertainties about the future and the very care these children require. We need to do something to help these caregivers better manage care, as well as cope with their own feelings. PMID: 30806443 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 27, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Hepatitis C in Hemodialysis Units: diagnosis and therapeutic approach.
Authors: Constancio NS, Ferraz MLG, Martins CTB, Kraychete AC, Bitencourt PL, Nascimento MMD Abstract According to data from the last census of the Brazilian Society of Nephrology (SBN), the prevalence of hepatitis C virus (HCV) in Brazilian hemodialysis units (HU) is 3.3%, about three times higher than what is reported for the Brazilian general population. Often, professionals working in HU are faced with clinical situations that require rapid HCV diagnosis in order to avoid horizontal transmission within the units. On the other hand, thanks to the development of new antiviral drugs, the cure of patients with HCV,...
Source: Jornal Brasileiro de Nefrologia - February 27, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Endothelial lesion and complement activation in patients with Scleroderma Renal Crisis.
We report a case of SRC in a patient with scleroderma-dermatomyositis overlap syndrome, which also showed clinical and histopathological data of TMA. On fundus examination, a severe acute hypertensive retinopathy was found. The kidney biopsy showed severe endothelial damage with widening of mucoid cells at the level of the intima, focal concentric proliferation on most small arterioles, and C3, C4d, and IgM deposits along the capillary walls. The genetic study of complement only showed the presence of membrane cofactor protein (MCP) risk haplotypes, without other genetic complement disorders. We understand that in a patien...
Source: Jornal Brasileiro de Nefrologia - February 27, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

The scenario of delayed graft function in Brazil.
Authors: Sandes-Freitas TV PMID: 30806446 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 27, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Focal and Segmental Glomerulosclerosis and Membranous Nephropathy overlapping in a patient with Nephrotic Syndrome: a case report.
CONCLUSIONS: In the present case, clinical and morphological characteristics showed a possible overlap of primary FSGS and MGN as focal and segmental glomerulosclerosis does not seem to be related with MGN progression but with the podocytopathy FSGS. PMID: 30806447 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 27, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Erratum: Clinical and laboratory features of urinary tract infections in young infants.
Authors: Abstract [This corrects the article doi: 10.1590/1678-4685-JBN-3602]. PMID: 30806448 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 27, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Effectiveness of sucroferric oxyhydroxide in patients on on-line hemodiafiltration in real-world clinical practice: A retrospective study.
Authors: Ferreira A, Pinto B, Navarro D, Aniceto J, Neves PL, Ponce P Abstract INTRODUCTION: Hyperphosphatemia is a serious consequence of chronic kidney disease and has been associated with an increased risk for cardiovascular disease. Controlling serum phosphorus levels in patients on dialysis is a challenge for the clinicians and implies, in most cases, the use of phosphate binders (PB). Part of the reason for this challenge is poor adherence to treatment because of the high pill burden in this patient group. OBJECTIVE: To assess the real-world effectiveness of sucroferric oxyhydroxide (SO) in controlling se...
Source: Jornal Brasileiro de Nefrologia - February 13, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

MicroRNAs: new biomarkers and promising therapeutic targets for diabetic kidney disease.
This study aimed to offer a narrative review on investigations around the use of microRNAs in the diagnosis, monitoring, and treatment of DKD. Various microRNAs are involved in the pathogenesis of DKD, while others have a role in nephroprotection and thus serve as promising therapeutic targets for DKD. Serum and urine microRNAs levels have also been considered in the early diagnosis and monitoring of individuals with DKD, since increases in albuminuria, decreases in the glomerular filtration rate, and progression of DKD have been linked to changes in the levels of some microRNAs. PMID: 30742700 [PubMed - as supplied by...
Source: Jornal Brasileiro de Nefrologia - February 13, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Montreal Cognitive Assessment for cognitive assessment in chronic kidney disease: a systematic review.
CONCLUSIONS: The instrument is efficient to be used in several stages and treatment modalities of the disease. We point to the need to adapt a cut-off point for the instrument in the different translations of the instrument. PMID: 30720849 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 6, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Clinical and microbiological effects of dialyzers reuse in hemodialysis patients.
CONCLUSION: Dialyzers reuse was safe from a clinical, microbiological, and inflammatory point of view. The dialyzer performance remained adequate until the 12th reuse. PMID: 30720850 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 6, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Quality of life of individuals with chronic kidney disease on dialysis.
This study aimed to measure the QOL of individuals with CKD and compare the QOL scores of patients with CKD to the scores of disease-free individuals to find factors associated with better QOL. METHOD: The local Ethics Committee approved this cross-sectional study. The study was carried out at a public clinic and a private hemodialysis clinic. Participants were asked to answer the WHOQOL-BREF and a sociodemographic questionnaire. Statistical tests were used according to the variables of interest and significance was attributed to differences with p-values
Source: Jornal Brasileiro de Nefrologia - February 6, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Macrophage migration inhibitory factor antagonist (p425) ameliorates kidney histopathological and functional changes in diabetic rats.
CONCLUSION: Collectively, these data suggested that MIF antagonist (p425) was able to protect against functional and histopathological injury in the DN. PMID: 30720852 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 6, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Uremic lion face syndrome.
Authors: Gameiro J, Duarte I, Outerelo C, Lopes JA Abstract Mineral bone disorder is a common feature of chronic kidney disease. Lion face syndrome is rare complication of severe hyperparathyroidism in end-stage renal disease patients, which has been less commonly reported due to dialysis and medical treatment advances in the last decade. The early recognition of the characteristic facial deformity is crucial to prompt management and prevent severe disfigurement. The authors present a rare case of severe hyperparathyroidism presenting with lion face syndrome and bone fractures. PMID: 30720853 [PubMed - as suppl...
Source: Jornal Brasileiro de Nefrologia - February 6, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Quality of life and mental health in hemodialysis patients: a challenge for multiprofessional practices.
Authors: Schmidt DB PMID: 30720854 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 6, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

A new look at phosphorus intake: what do we eat here is what they eat there?
Authors: Ramos CI, Cuppari L PMID: 30720855 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - February 6, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Demographic, clinical characteristics and cardiovascular disease burden in a Portuguese cohort of older chronic kidney disease patients.
Authors: Lascasas JMSS, Fonseca I, Malheiro J, Santos S, Campos A, Castro A, Moreira C, Correia S, Beirão I, Lobato L, Cabrita A Abstract INTRODUCTION: Chronic kidney disease (CKD) is an independent risk factor for several unfavorable outcomes including cardiovascular disease (CVD), particularly in the elderly, who represent the most rapidly growing segment of the end-stage kidney disease (ESKD) population. Portugal has the highest European unadjusted incidence and prevalence rates of ESKD. In 2012, we started to follow a cohort of elderly CKD patients, we describe their baseline characteristics, risk profil...
Source: Jornal Brasileiro de Nefrologia - January 16, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Takayasu arteritis: differential diagnosis in a teenager with severe acute kidney injury - a case report.
This report describes the case of a 15-year-old female with constitutional symptoms evolving for a year, combined with headache, nausea, and vomiting, in addition to frequent visits to emergency services and insufficient clinical examination. The patient worsened significantly six months after the onset of symptoms and developed acute pulmonary edema, oliguria, acute kidney injury, and difficult-to-control hypertension, at which point she was admitted for intensive care and hemodialysis. Initial ultrasound examination showed she had normal kidneys and stenosis-free renal arteries. The patient was still anuric after 30 days...
Source: Jornal Brasileiro de Nefrologia - January 16, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

High grade renal trauma due to blunt injury in children: do all require intervention?
CONCLUSION: Children with major grade renal trauma due to blunt injury can be successfully managed without surgical intervention and minimal intervention may only be needed in select situations. PMID: 30638253 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - January 16, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Arteriovenous fistulas in hemodialysis: factors of success and the role of nephrologists.
Authors: Franco RP Abstract PMID: 30625232 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - January 11, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Metabolic and volume status evaluation of hemodialysis patients with and without residual renal function in the long interdialytic interval.
Authors: Almeida LLS, Sette LHBC, Fonseca FLA, Bezerra LSVDS, Oliveira Júnior FH, Bérgamo RR Abstract INTRODUCTION: It is unclear whether residual renal function (RRF) in dialysis patients can attenuate the metabolic impact of the long 68-hour interdialytic interval, in which water, acid, and electrolyte accumulation occurs. OBJECTIVE: to evaluate serum electrolyte levels, water balance, and acid-base status in dialytic patients with and without RRF over the long interdialytic interval (LII). METHODOLOGY: this was a single-center, cross-sectional, and analytical study that compared patients wi...
Source: Jornal Brasileiro de Nefrologia - January 10, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Bone biopsy in nephrology practice.
Authors: Barreto FC, Costa CRVD, Reis LMD, Custódio MR Abstract Renal osteodystrophy (ROD), a group of metabolic bone diseases secondary to chronic kidney disease (CKD), still represents a great challenge to nephrologists. Its management is tailored by the type of bone lesion - of high or low turnover - that cannot be accurately predicted by serum biomarkers of bone remodeling available in daily clinical practice, mainly parathyroid hormone (PTH) and alkaline phosphatase (AP). In view of this limitation, bone biopsy followed by bone quantitative histomorphometry, the gold-standard method for the diagnosis of...
Source: Jornal Brasileiro de Nefrologia - December 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Resistant and refractory hypertension: two sides of the same disease?
In conclusion, both RH and RfH constitute challenges in clinical practice and should be addressed as distinct clinical entities by trained professionals who are capable to identify comorbidities and provide specific, diversified, and individualized treatment. PMID: 30525180 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - December 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Chronic kidney disease patients who smoke have higher serum phosphorus.
CONCLUSION: Smoking confers a higher cardiovascular risk to CKD patients under conservative treatment as it is associated with higher levels of P. Further studies are needed to confirm and better elucidate this finding. PMID: 30534856 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - December 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Cecum perforation associated with a calcium polystyrene sulfonate bezoar - a rare entity.
Authors: Fiel DC, Santos I, Santos JE, Vicente R, Ribeiro S, Silva A, Malvar B, Pires C Abstract Hyperkalemia is one of the most common electrolyte disorders, responsible for a high number of adverse outcomes, including life-threatening arrhythmias. Potassium binders are largely prescribed drugs used for hyperkalemia treatment but unfortunately, there are many adverse events associated with its use, mostly gastrointestinal. Identification of patients at highest risk for the serious complications associated with the current potassium binders, such as colon necrosis and perforation, could prevent fatal outcomes. The ...
Source: Jornal Brasileiro de Nefrologia - December 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Differences in phosphatemia and frequency of consumption of dietary sources of phosphorus in hemodialysis patients in southern and northern Brazil.
Authors: Nerbass FB, Canzi ER, Araujo RDA, Corrêa D, Santos RGD, Vieira MA, Morais JG Abstract INTRODUCTION: Hyperphosphatemia is associated with unfavorable outcomes, and the percentage of patients presenting with this condition in hemodialysis (HD) in kidney foundation units in the state of Santa Catarina (SC) is historically higher than that of patients in the state of Tocantins (TO). OBJECTIVE: To assess the frequency of consumption of the main dietary sources of phosphorus and to compare them between the two states. METHODOLOGY: A cross-sectional study was carried out involving 123 patients, 66 o...
Source: Jornal Brasileiro de Nefrologia - December 12, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Pediatric lupus nephritis.
Authors: Pinheiro SVB, Dias RF, Fabiano RCG, Araujo SA, Silva ACSE Abstract Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options. PMID:...
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Acute Kidney Injury Epidemiology in pediatrics.
Authors: Cleto-Yamane TL, Gomes CLR, Suassuna JHR, Nogueira PK Abstract We performed a search in the MEDLINE database using the MeSH term: "Acute Kidney Injury", selecting the subtopic "Epidemiology", and applying age and year of publication filters. We also searched for the terms: "acute renal failure" and "epidemiology" "acute tubular necrosis" and "epidemiology" in the title and summary fields with the same filters. In a second search, we searched in the LILACS database, with the terms: "acute renal injury", or "acute renal failure" ...
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Multidisciplinary approach for patients with nephropathic cystinosis: model for care in a rare and chronic renal disease.
Authors: Vaisbich MH, Satiro CAF, Roz D, Nunes DAD, Messa ACHL, Lanetzki C, Ferreira JCOA Abstract Care for patients with chronic and rare diseases is complex, especially considering the lack of knowledge about the disease, which makes early and precise diagnosis difficult, as well as the need for specific tests, sometimes of high complexity and cost. Added to these factors are difficulties in obtaining adequate treatment when available, in raising patient and family awareness about the disease and treatment compliance. Nephropathic cystinosis is among these diseases. After more than 20 years as a care center for t...
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Parathyroidectomy in the treatment of BMD-DRC Brazil: many limitations, but still fundamental.
Authors: Carmo LPF PMID: 30465593 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Erratum.
Authors: Abstract [This corrects the article doi: 10.1590/2175-8239-JBN-2018-00030003] [This corrects the article doi: 10.1590/2175-8239-JBN-2018-00030002][This corrects the article doi: 10.1590/1678-4685-JBN-2018-00020001]. PMID: 30465594 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 24, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Intradialytic resistance training: an effective and easy-to-execute strategy.
CONCLUSION: IRT led to significant increases in PC and higher scores in all domains of QoL. Important adverse events were not observed during intradialytic resistance training. PMID: 30421780 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Pathogenesis, histopathologic findings and treatment modalities of lipoprotein glomerulopathy: A review.
Authors: Cambruzzi E, Pêgas KL Abstract Lipoprotein glomerulopathy (LPG) is an uncommon cause of nephrotic syndrome and/or kidney failure. At microscopy, LPG is characterized by the presence of lipoprotein thrombi in dilated glomerular capillaries due to different ApoE mutations. ApoE gene is located on chromosome 19q13.2, and can be identified in almost all serum lipoproteins. ApoE works as a protective factor in atherosclerosis due its interaction with receptor-mediated lipoprotein clearance and cholesterol receptor. Most common polymorphisms include ApoE2/2, ApoE3/2, ApoE3/3, ApoE4/2, ApoE4/3, and ApoE4/4....
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Association between religiosity and happiness in patients with chronic kidney disease on hemodialysis.
CONCLUSIONS: Patients on hemodialysis showed high levels of R/S, which correlated with higher happiness levels. Clinical and sociodemographic variables were not correlated with patients' happiness. Psychosocial variables such as R/S and SC are potential key targets for interventions to promote better survival quality among CKD patients. PMID: 30421782 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Micro RNA 146a-5p expression in Kidney transplant recipients with delayed graft function.
CONCLUSION: We conclude that miR-146a-5p expression has a distinct pattern in the renal tissue and perhaps in the peripheral blood in the setting of DGF. Further refinements and strategies for studies should be developed in the field of non-invasive molecular diagnosis of kidney graft dysfunction. PMID: 30421783 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Hypertension in patients on dialysis: diagnosis, mechanisms, and management.
Authors: Bucharles SGE, Wallbach KKS, Moraes TP, Pecoits-Filho R Abstract Hypertension (blood pressure> 140/90 mm Hg) is very common in patients undergoing regular dialysis, with a prevalence of 70-80%, and only the minority has adequate blood pressure (BP) control. In contrast to the unclear association of predialytic BP recordings with cardiovascular mortality, prospective studies showed that interdialytic BP, recorded as home BP or by ambulatory blood pressure monitoring in hemodialysis patients, associates more closely with mortality and cardiovascular events. Although BP is measured frequently in the dialys...
Source: Jornal Brasileiro de Nefrologia - November 15, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Carotid artery thickness in obese patients with chronic renal failure.
Authors: Santos VMD Abstract PMID: 30353908 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 26, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

The future is coming: promising perspectives regarding the use of machine learning in renal transplantation.
CONCLUSION: The way we deal with storage data in electronic health records will radically change in the coming years and machine learning will be part of clinical daily routine, whether to predict clinical outcomes or suggest diagnosis based on institutional experience. PMID: 30353909 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 26, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Crisis management and the dilemma of rationing strategies in healthcare organizations.
Authors: Moura-Neto JA, Moura AF, Moura JA Abstract PMID: 30353910 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 26, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Hemophagocytic lymphohistiocytosis, a rare condition in renal transplant - a case report.
We report a case of a 50-year-old renal transplant female admitted with fever and malaise 3 months post-transplant and presenting anemia, fever, hypertriglyceridemia, high levels of serum ferritin, and positive CMV antigenemia. Urine was positive for decoy cells and BKV-DNA. Graft biopsy showed CMV nephritis. Both blood and urine cultures where positive for E. coli. Hemophagocytosis was confirmed by bone marrow aspiration. Immunosuppression was reduced, and the patient received high-dose intravenous immunoglobulin and dexamethasone, with complete response after 3 weeks. We highlight the importance of early diagnosis and pr...
Source: Jornal Brasileiro de Nefrologia - October 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Albuminuria and glomerular filtration rate in obese children and adolescents.
CONCLUSION: Albuminuria, although frequent in children and adolescents with obesity, was not associated with other morbidities and the glomerular filtration rate in these patients. PMID: 30328467 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Long-term effects of delayed graft function duration on function and survival of deceased donor kidney transplants.
Authors: Helfer MS, Pompeo JC, Costa ORS, Vicari AR, Ribeiro AR, Manfro RC Abstract INTRODUCTION: Delayed graft function (DGF) is a frequent complication after deceased donor kidney transplantation with an impact on the prognosis of the transplant. Despite this, long-term impact of DGF on graft function after deceased donor kidney transplantation has not been properly evaluated. OBJECTIVE: The main objective of this study was to evaluate risk factors for DGF and the impact of its occurrence and length on graft survival and function. METHODS: A retrospective cohort study was performed in 517 kidney transplan...
Source: Jornal Brasileiro de Nefrologia - October 11, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Translumbar hemodialysis long-term catheters: an alternative for vascular access failure.
CONCLUSION: TLDC is an option for patients with VA failure, improving survival and acting as a bridge for renal transplantation. PMID: 30281060 [PubMed - as supplied by publisher] (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Successful multiple-exchange peritoneal dialysis in a patient with severe hematological toxicity by methotrexate: case report and literature review.
We present the case of a 68-year-old man with chronic, end-stage renal disease associated with ANCA vasculitis, under treatment with peritoneal dialysis, who received the medication at a low dose, indicated by disease activity, which presented as a complication with severe pancytopenia with mucositis that improved with support measures and multiple-exchange peritoneal dialysis. We reviewed 20 cases published to date of pancytopenia associated with methotrexate in patients on dialysis and found high morbidity and mortality, which is why its use in this type of patient is not recommended. However, when this complication occu...
Source: Jornal Brasileiro de Nefrologia - October 5, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research