Low Cost Medical Devices for Low-Resource Regions: Interview with Prof. Saad Bhamla, Georgia Tech

Advances in medical technology continue apace, with sophisticated new medical devices and therapies becoming available on an ongoing basis. However, medical technology often comes at a premium, and for low-resource regions sometimes even relatively b...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Critical Care Diagnostics Emergency Medicine ENT Exclusive Genetics Materials Pathology Public Health Source Type: blogs

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In this study, we genetically characterised Monogenea found on the gill of common carp in Iran. In total, 5603 parasites were recovered from 112 fish. The parasites were first identified morphologically as Dactylogyrus extensus, D. anchoratus, D. vastator, D. minutus, D. achmerowi and Gyrodactylus sprostonae. Representative samples were then subjected to sequencing. This is one of the first studies which has provided both morphological and sequence data for Dactylogyrus spp. and G. sprostonae. Our findings provide a foundation for future research into the genetic make-up of these economically significant parasites and the ...
Source: Parasitology International - Category: Parasitology Source Type: research
Publication date: Available online 22 August 2019Source: Advances in Virus ResearchAuthor(s): M. Alejandra Tortorici, David VeeslerAbstractCoronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and was responsible for an epidemic that spread to five continents with a fatality rate of 10% before being contained in 2003 (with additional cases reported in 2004). The Middle-East respiratory syndrome coronavirus (MERS-CoV) emerged in the Arabian Peninsula in 2012 and has caused recurrent outbre...
Source: Advances in Virus Research - Category: Virology Source Type: research
Abstract Synthetic dyes are toxic and carcinogenic in nature, which also causes environmental pollution. The present study was aimed to decolorize various commercial dyes using purified recombinant bacterial laccases. Laccase gene from Yersinia enterocolitica strain 8081 (yacK), Y. enterocolitica strain 7 (yacK) and Bacillus pumilus DSKK1 was cloned in vector pET28a and overproduced in host Escherichia coli BL21. The high yield of recombinant laccase protein resulted in the formation of inclusion bodies, which were further solubilized, refolded, and purified. The purified recombinant laccases were alkali-tole...
Source: Environmental Pollution - Category: Environmental Health Authors: Tags: Environ Pollut Source Type: research
Publication date: Available online 21 August 2019Source: Journal of Molecular LiquidsAuthor(s): Jitendra Kumar Sahoo, Monidipa Konar, Juhi Rath, Devendra Kumar, Harekrushna SahooAbstractThe current investigation reports the removal of Eriochrome Black T (EBT) from aqueous solution by using magnetic hydroxyapatite (M-HAP), a cost-effective adsorbent compared to the other commercial adsorbents. The M-HAP nanocomposite was characterized by Fourier transform infrared (FTIR), X-ray diffraction (XRD), Field emission scanning electron microscope (FE-SEM), Environmental scanning electron (E-SEM), BET surface area analyser, vibrati...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 23 August 2019Source: Journal of Theoretical BiologyAuthor(s): Amir Hossein Amiri Mehra, Iman Zamani, Zohreh Abbasi, Asier IbeasAbstractThis paper presents a new Susceptible, Exposed, Infected, Asymptomatic, and Recovered individuals (SEIAR) model for influenza considering a dynamic population. In the given model, the possibility of transmission of asymptomatic individuals (infectious with no visible symptoms) to infected individuals (infectious exhibiting symptoms) is considered. The basic reproduction number and the equilibrium points of the new model are given while the stability of th...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
In this study, a Δ2 mutant that deletion of D2 fragment in parental virulent strain HN016 was constructed, and the safety, stability, immunogenicity, and growth characteristics, as well as the virulence mechanism of Δ2 mutant were evaluated. The results showed that Δ2 mutant was not pathogenic to tilapia, and the virulent revertants were not observed after 50 generations of passage. The RPS reached 96.11% at 15 days and 93.05% at 30 days, respectively, after intraperitoneal injection, while RPS reached 74.80% at 15 days and 53.16% at 30 days, respectively, after oral immunization. The growth of Δ2 m...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: October 2019Source: Fish &Shellfish Immunology, Volume 93Author(s): Jiwan K. Chettri, Azmi Al-Jubury, Marie B. Hansen, Allan Lihme, Inger Dalsgaard, Kurt Buchmann, Peter M.H. HeegaardAbstractTightened regulations and an environmentally friendly approaches in fish production have greatly reduced the use of antibiotics but green solutions are continuously being explored. The use of functional feed may have a potential in the aquaculture sector in securing biomass and minimizing the loss from disease. In the present study, we tested the concept that blood from the fish slaughterhouse can be used for mass...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 23 August 2019Source: BiologicalsAuthor(s): W.P. Paim, M.N. Weber, S.P. Cibulski, M.S. da Silva, D.E. Puhl, R.F. Budaszewski, A.P.M. Varela, F.Q. Mayer, C.W. CanalAbstractHorses are often used as blood donors for commercial horse serum (HS) production and to manufacture biologicals. HS is an alternative for fetal bovine serum (FBS) used as a supplement for cell culture and vaccine production. Furthermore, HS is also frequently obtained in order to produce antisera toxins and pathogens. The advent of high-throughput sequencing (HTS) has promoted changes in virus detection, since previous k...
Source: Biologicals - Category: Biology Source Type: research
In this study, we successfully developed new thiol chitosan-wrapped gold nanoshells (TC-AuNSs) as an antibacterial agent for the near-infrared (NIR) laser-triggered photothermal destruction of antibiotic-resistant pathogens, such as Gram-positive bacteria (Staphylococcus aureus) and Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli), owing to their high water solubility, biocompatibility, strong NIR absorption, and outstanding photothermal properties. More interestingly, TC-AuNSs (115 µg/mL) were capable of completely destroying S. aureus, P. aeruginosa, and E.coli within 5 min of NIR ...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
In this study, LNPs were prepared from corncob lignin via anti-solvent precipitation method, and then characterized by FTIR, TGA, AFM, and NMR. The CNF@CLNPs composite film was fabricated by blending CLNPs with CNF. The results showed that the CLNPs had an average diameter of about 118 nm, meanwhile the main structures and properties of corncob lignin were maintained. The CNF@CLNPs composite film exhibited a high ultraviolet resistance, and a good antibacterial activity against both Escherichia coli and Staphylococcus aureus. It is expected that the CNF@CLNPs composite film would have potential applications in outdo...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
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