Cardiology MCQ Test 5

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Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs

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Publication date: Available online 22 October 2019Source: Sensors and Actuators A: PhysicalAuthor(s): Dong Sun, Yu-juan Tang, Jiong Wang, Xin-jie WangAbstractIn this contribution, an H-shaped piezoelectric motor based safety and arming device that is driven by the hybrid of symmetrical first longitudinal mode and second bending mode is proposed, designed and experimental investigated. The proposed system operates based on the concept of self-moving and show potential infield of fuse system with different calibers. The actuating mechanism is that the four driving feet contact with the guides alternately and push the motor t...
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research
Publication date: Available online 23 October 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): V. Arroyo-Jousse, A. Jaramillo, E. Castaño-Moreno, M. Lépez, K. Carrasco-Negüe, P. CasanelloAbstractMaternal pregestational obesity is a well-known risk factor for offspring obesity, metabolic syndrome, cardiovascular disease and type 2 diabetes. The mechanisms by which maternal obesity can induce alterations in fetal and later neonatal metabolism are not fully elucidated due to its complexity and multifactorial causes. Two adipokines, leptin and adiponectin, are involved i...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
Publication date: Available online 22 October 2019Source: Saudi Journal of Biological SciencesAuthor(s): Mohammad I. Al-Obaida, Alaa K.M. Al-Nakhli, Ibrahim A. Arif, Asmaa Faden, Sahar Al-Otaibi, Bushra Al-Eid, Aishah Ekhzaimy, Haseeb A. KhanAbstractPeriodontal disease is a chronic infectious disease, which is characterized by the damaged dental hard tissue by lactic acid generated by microorganisms after the fermentation of carbohydrates rich diet. The risk of periodontal disease is known to be higher in diabetic patients. We compared the diversity of five commonly occurring dental bacteria including Porphyromonas gingiva...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: Available online 22 October 2019Source: Redox BiologyAuthor(s): Ziwei Wang, M. Corina Litterio, Michael Müller, David Vauzour, Patricia I. OteizaAbstractSecondary bile acids promote gastrointestinal (GI) tract permeabilization both in vivo and in vitro. Consumption of high fat diet s increases bile acid levels in the GI tract which can contribute to intestinal permeabilization and consequent local and systemic inflammation. This work investigated the mechanisms involved in bile acid (deoxycholic acid (DCA))-induced intestinal epithelial cell monolayer permeabilization and the preventive capacity of (...
Source: Redox Biology - Category: Biology Source Type: research
Publication date: Available online 23 October 2019Source: Life SciencesAuthor(s): Qi Li, Xinglan An, Xiaxia Man, Meiran Chu, Tianchuang Zhao, Hao Yu, Ziyi LiAbstractAimsThe present study aimed to investigate the effects of cyclophosphamide (Cytoxan, CTX) on premature ovarian failure (POF) in mice and its regulatory mechanisms by transcriptome analysis.Main methodsFemale C57BL/6 mice were treated with a single intraperitoneal injection of 70 mg/kg CTX. Serum levels of estradiol (E2) and follicle stimulating hormone (FSH) were measured by enzyme-linked immunosorbent assay (ELISA), and follicular structure differences were ob...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 22 October 2019Source: Life SciencesAuthor(s): Chao He, Guiting Zhang, Hang Ouyang, Peng Zhang, Yudan Chen, Ren Wang, Hong ZhouAbstractAimsβ2-glycoprotein I/anti-β2-glycoprotein I antibody complex (β2/aβ2) could promote oxLDL-induced endothelial inflammation through Toll-like receptor 4 (TLR4), therefore accelerates atherosclerosis in patients with anti-phospholipid syndrome (APS). However, effects of β2/aβ2 and TLR4 on oxLDL-induced CD36 activation in macrophages remain to be elucidated and are currently under investigation.Materials and MethodsTHP-1 macroph...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 23 October 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Margarida Lorigo, Melissa Mariana, Manuel C. Lemos, Elisa CairraoAbstractTestosterone (T) is the predominant endogenous androgen in the bloodstream. At the vascular level, T presents genomic and non-genomic effects, and both effects may overlap. The genomic actions assume that androgens can freely cross the plasma membrane of target cells and bind to nuclear androgen receptors, inducing gene transcription and protein synthesis. The non-genomic effects have a more rapid onset and may be related to th...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 22 October 2019Source: Pharmacology Biochemistry and BehaviorAuthor(s): Steven Wesley Beckwith, Cristine Lynn CzachowskiAbstractIncreased subjective discounting of delayed rewards is associated with substance abuse, and individuals tend to discount their drug of choice at a greater rate compared to monetary rewards. While there is evidence indicating that increased delay discounting (DD) is a risk factor for substance abuse, some results suggest that exposure to drugs of abuse also increases DD, but effects are mixed. The current study examined whether ethanol pre-exposure increases DD an...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
Publication date: Available online 22 October 2019Source: Nitric OxideAuthor(s): Neeru M. Sharma, Andrea S. Haibara, Kenichi Katsurada, Xuefei Liu, Kaushik P. PatelAbstractActivation of renin-angiotensin- system, nitric oxide (NO•) bioavailability and subsequent sympathoexcitation plays a pivotal role in the pathogenesis of many cardiovascular diseases, including hypertension. Previously we have shown increased protein expression of PIN (a protein inhibitor of nNOS: neuronal nitric oxide synthase, known to dissociate nNOS dimers into monomers) with concomitantly reduced levels of catalytically active dimers of nNOS in...
Source: Nitric Oxide - Category: Chemistry Source Type: research
Publication date: Available online 22 October 2019Source: Journal of Organometallic ChemistryAuthor(s): Anand Ratnam, Sheela Kumari, Rajan Kumar, U.P. Singh, Kaushik GhoshAbstractIn this work, four ruthenium complexes [Ru(L1−4)(PPh3)Cl2](1–4) containing phenolate-imine ligands [L1−4H = condensed product of 2-(1-phenylhydrazinyl)-pyridine with different substituted salicylaldehyde, H = phenolic dissociable proton] were synthesized and characterized by different spectroscopic methods like IR and UV–visible spectral studies. Solid-state structures of complexes 1 and 2 were determined by single-...
Source: Journal of Organometallic Chemistry - Category: Chemistry Source Type: research
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