How Common are Aortic Aneurysms?
Discussion Aortic root dilatation or thoracic aortic aneurysm occurs in 6:100,000 individuals> 50 years of age. It is due to aging, hypertension, hypercholesterolemia, and smoking. Tertiary syphilis was a cause in the preantibiotic era. Pediatric aneurysms are very uncommon but the exact prevalence is different due to the various causes. Aneurysms are due to genetic disorders, congenital anomalies or post-surgical repair. In pediatric patients with sudden cardiac deaths, 5.4% are due to ruptured thoracic aortic aneurysms. Learning Point Some causes of pediatric aneurysms include: Familial thoracic aneurysm and dissecti...
Source: PediatricEducation.org - February 22, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Using a machine model to predict risk of human aneurysms
(University of Pittsburgh) An abdominal aortic aneurysm can be a ticking time bomb if undiscovered in time. It occurs when the aorta weakens and begins to irreversibly dilate, like a slowly inflating balloon. If left untreated, the risk of rupture increases and has a 90 percent rate of mortality. Researchers at the University of Pittsburgh are developing a new model to better predict at-risk patients, and the tools they are using apply mechanical testing to the human body. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 16, 2021 Category: International Medicine & Public Health Source Type: news

Endovascular aneurysm repair linked to higher readmission rates
(University of Missouri-Columbia) Ruptured abdominal aortic aneurysms (rAAA) are responsible for nearly 2% of all deaths in U.S. men over the age of 65. Endovascular aneurysm repair (EVAR) has emerged as a newer and less invasive alternative to open repair for rAAA. But researchers from the University of Missouri School of Medicine have discovered that while EVAR is more commonly utilized for rAA, the odds of hospital readmission after EVAR are 1.5 times higher compared to traditional open repair. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 10, 2021 Category: International Medicine & Public Health Source Type: news

Time to Broaden Warning on Fluoroquinolones to All Adults? Time to Broaden Warning on Fluoroquinolones to All Adults?
A new study confirms and strengthens the association between fluoroquinolone antibiotics and increased risk of aortic aneurysm, prompting calls to broaden warnings to include all adults, not just high-risk adults.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 19, 2021 Category: Surgery Tags: General Surgery News Source Type: news

Certain Antibiotics Linked With Upped Risk for Deadly Aortic Aneurysms
Title: Certain Antibiotics Linked With Upped Risk for Deadly Aortic AneurysmsCategory: Health NewsCreated: 1/7/2021 12:00:00 AMLast Editorial Review: 1/8/2021 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - January 8, 2021 Category: Cardiology Source Type: news

Certain Antibiotics Linked With Upped Risk for Deadly Aortic Aneurysms
THURSDAY, Jan. 7, 2021 -- A widely used class of antibiotics has been linked to an increased risk of a potentially fatal blood vessel condition -- even in younger, healthy people. In a study of millions of antibiotic prescriptions made in the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 7, 2021 Category: General Medicine Source Type: news

Prognosis After AAA Repair is Poor in Women and Men Prognosis After AAA Repair is Poor in Women and Men
Despite substantial changes in abdominal aortic aneurysm management, the long-term survival of these patients remains poor. What factors may account for this?Annals of Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 17, 2020 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

A new treatment approach for deadly aneurysms
Yale Medicine vascular surgeons treat at least 80% of aortic aneurysms with minimally invasive approaches —and that includes some of the most complicated cases. (Source: Yale Science and Health News)
Source: Yale Science and Health News - October 9, 2020 Category: Universities & Medical Training Source Type: news

14 Novel Loci Identified for Abdominal Aortic Aneurysm
MONDAY, Sept. 28, 2020 -- In a genome-wide association study (GWAS), published online Sept. 28 in Circulation, researchers identified 14 novel loci for abdominal aortic aneurysm (AAA). Philip Tsao, Ph.D., from the Stanford University School of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 28, 2020 Category: Pharmaceuticals Source Type: news

‘I Had Heart Surgery in the Middle of a Coronavirus Hot Spot’
Anxiety and uncertainty about the pandemic is leading some patients to delay surgery. But how safe is that when you have an aneurysm in your heart? (Source: NYT Health)
Source: NYT Health - September 22, 2020 Category: Consumer Health News Authors: Johnny Diaz Tags: Coronavirus (2019-nCoV) Surgery and Surgeons Hospitals Aneurysms Miami Beach (Fla) Florida New York City Covid-19 precautions valve sparing aortic root repair. Heart Quarantines Mount Sinai Medical Center aortic aneurysm Source Type: news

Abdominal Aortic Aneurysm
Title: Abdominal Aortic AneurysmCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 8/18/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - August 18, 2020 Category: Cardiology Source Type: news

University of Edinburgh seeks - Research Fellow
The Usher Institute at the University of Edinburgh is seeking a highly skilled and motivated epidemiologist/research fellow to work in the field of vascular disease, including both the diagnosis and treatment of peripheral vascular diseases and the development of vascular complications of type 2 diabetes. The primary role will be to undertake a series of high quality systematic reviews on the prevention, diagnosis and treatment of vascular diseases, including abdominal aortic aneurysm, venous thromboembolism and peripheral arterial disease, within the core programme of work which constitutes the CSO funded research project...
Source: Cochrane News and Events - July 22, 2020 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Doxycycline Does Not Cut Growth of Abdominal Aortic Aneurysms
WEDNESDAY, June 3, 2020 -- Doxycycline does not significantly reduce aneurysm growth compared with placebo among patients with small infrarenal abdominal aortic aneurysms, according to a study published in the May 26 issue of the Journal of the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 3, 2020 Category: Pharmaceuticals Source Type: news

Temple researchers track new path to therapeutic prevention of abdominal aortic aneurysm
(Temple University Health System) New research by scientists at the Lewis Katz School of Medicine at Temple University suggests that abdominal aortic aneurysm (AAA) can be prevented therapeutically. In work published online May 28 in the journal Cardiovascular Research, they show for the first time in animals that blocking a molecule known as dynamin-related protein 1 (Drp1) can stop AAA from developing. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 28, 2020 Category: Biology Source Type: news

Doxycycline ineffective at shrinking aortic aneurysms in two-year study
(Vanderbilt University Medical Center) Patients with a vascular condition called abdominal aortic aneurysm did not benefit from taking the common antibiotic doxycycline for two years to shrink the aneurysm when compared to those who took a placebo, according to a Vanderbilt University Medical Center (VUMC) study published in the Journal of the American Medical Association (JAMA). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 27, 2020 Category: International Medicine & Public Health Source Type: news

Researchers find no benefit for treatment used to avoid surgery for abdominal aortic aneurysm
(University of Maryland School of Medicine) A new landmark study by researchers at the University of Maryland School of Medicine (UMSOM) found that patients with a vascular condition, called abdominal aortic aneurysm, received no benefits from taking a common antibiotic drug to reduce inflammation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 26, 2020 Category: International Medicine & Public Health Source Type: news

Polygenic Risk Score Helps Target AAA Screening Polygenic Risk Score Helps Target AAA Screening
The score, based on analysis of 29 discrete genetic variants linked with abdominal aortic aneurysms, appeared better than the current criteria that clinicians use to identify people to screen for AAA.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 14, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

More Medical Device Businesses Impacted by COVID-19
The uncertainty surrounding COVID-19 is making it difficult for public companies to accurately forecast 2020 earnings. Irvine, CA-based Endologix recently joined a growing list of medical device companies that have withdrawn previously-reported financial guidance for the year. The company makes endovascular stent grafts for the treatment of abdominal aortic aneurysms (AAA). AAA is a weakening of the wall of the aorta, the largest artery in the body, resulting in a balloon-like enlargement. Once an AAA develops, it continues to enlarge and, if left untreated, becomes increasingly susceptible to rupture. Endologix said AAA p...
Source: MDDI - April 6, 2020 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

New findings boost understanding of arterial aneurysm
(University of Gothenburg) Abdominal arterial (or aortic) aneurysm in older men is associated with levels of certain subtypes of white blood cells, a study from the University of Gothenburg, Sweden, shows. The study results belong to an expanding research field that is expected improve both knowledge of the disease and treatment options. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 16, 2020 Category: International Medicine & Public Health Source Type: news

Aneurysm Diameter, Intraluminal Thrombus Predict AAA Growth
THURSDAY, Feb. 6, 2020 -- Maximum diameter and presence of intraluminal thrombus (ILT) are independent predictors of abdominal aortic aneurysm (AAA) growth, according to a study published online Jan. 28 in Radiology. Chengcheng Zhu, Ph.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 6, 2020 Category: Pharmaceuticals Source Type: news

Presence of Blood Clot Tied to Accelerated AAA Progression Presence of Blood Clot Tied to Accelerated AAA Progression
The maximal diameter of an abdominal aortic aneurysm (AAA) and the presence of an intraluminal thrombus (ILT) are both independent predictors of faster aneurysm growth, according to a new study.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - February 6, 2020 Category: Radiology Tags: Cardiology News Source Type: news

Staff shortage forces service centralisation ahead of plan
Surgery for aortic aneurysms has been moved out of a hospital ahead of schedule, following an emergency reconfiguration of services caused by staff shortages. (Source: HSJ)
Source: HSJ - February 4, 2020 Category: UK Health Source Type: news

Patients face longer journeys after emergency surgery centralised
Patients from some parts of Kent needing surgery for aortic aneurysms are having to travel 30 miles away, following an emergency reconfiguration of services. (Source: HSJ)
Source: HSJ - February 4, 2020 Category: UK Health Source Type: news

Should We Worry About Bicuspid Aortic Valve?
Discussion The aortic valve usually has 3 leaflets. In bicuspid aortic valve (BAV) there are 2 asymmetric leaflets with a fish-mouthed orifice between them which may not open fully. It occurs in about 0.5-2% of the population making it one of the most common congenital heart anomalies and the most common one in adults. Transmission is autosomal dominant yet males are more likely to have BAV, indicating potential reduced penetrance in females. “BAVs are different, however, in that the tissue pathology is not limited to the valves’ leaflets but extends from the left ventricular outflow tract to the ascending thor...
Source: PediatricEducation.org - January 27, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

USPSTF Recommends Screening Older Men Who Smoked for AAA
On Dec. 10, the U.S. Preventive Services Task Force posted a final recommendation statement on screening for abdominal aortic aneurysm in asymptomatic patients, with recommendations included in that statement varying based on sex, age, smoking status and family history. (Source: AAFP News)
Source: AAFP News - December 11, 2019 Category: Primary Care Source Type: news

USPSTF Advises AAA Screening Based on Sex, Age, Smoking History
TUESDAY, Dec. 10, 2019 -- The U.S. Preventive Services Task Force (USPSTF) recommendations for abdominal aortic aneurysm (AAA) screening vary by sex, smoking status, and family history. These recommendations form the basis of a final recommendation... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 10, 2019 Category: Pharmaceuticals Source Type: news

Aortic aneurysms: Mayo Clinic Radio Health Minute
An aortic aneurysm is an abnormal bulge that occurs in the wall of the aorta, the major blood vessel that carries blood from your heart to your body. if it bursts a person could bleed to death. In this Mayo Clinic Radio Health Minute, Dr. Gustavo Oderich lists some of the risk factors for an [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 1, 2019 Category: Databases & Libraries Source Type: news

FDA Issues Safety Alert for Endologix AAA Duraply Repair Grafts FDA Issues Safety Alert for Endologix AAA Duraply Repair Grafts
The FDA warns of potentially higher risk for type III endoleaks with two Endologix endovascular grafts that use Duraply graft material to repair of abdominal aortic aneurysm.News Alerts (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - October 28, 2019 Category: Cardiology Tags: Cardiology News Alert Source Type: news

Sex Disparity in Abdominal Aortic Aneurysm Repair Outcomes Sex Disparity in Abdominal Aortic Aneurysm Repair Outcomes
Do sex-related differences exist in mortality after repair of ruptured abdominal aortic aneurysm? Is the timeliness of repair a factor?Annals of Surgery (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - September 25, 2019 Category: Surgery Tags: General Surgery Journal Article Source Type: news

Endologix Takes a Step Forward with Nellix IDE
Endologix has received investigational device exemption (IDE) approval from FDA for a new pivotal study to evaluate the safety and effectiveness of the Nellix Chimney Endovascular Aneurysm Sealing System for the endovascular treatment of complex abdominal aortic aneurysms (AAA). The system is an endovascular abdominal aortic aneurysm therapy designed to combine the Nellix 3.5 endograft with parallel visceral stents to enable treatment of patients with juxta-renal, para-renal, and suprarenal AAA. The application of endovascular aneurysm sealing for patients with complex aneurysms will offer innovativ...
Source: MDDI - August 9, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Regulatory and Compliance Source Type: news

Medical News Today: What causes a pulse in the stomach?
Feeling a pulse in the stomach, or abdomen, is not a cause for concern in some people. However, in others, it may indicate an aortic aneurysm. Learn more about the causes, risk factors, and symptoms here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 18, 2019 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

USPSTF Recommends Screening Older Men Who Smoked for AAA
On June 18, the U.S. Preventive Services Task Force posted a draft recommendation statement on screening for abdominal aortic aneurysm in asymptomatic patients. Men ages 65-75 who smoke or used to smoke benefit most from screening; the task force recommends one-time screening with ultrasonography in this group. (Source: AAFP News)
Source: AAFP News - July 8, 2019 Category: Primary Care Source Type: news

Scientists find potential way to defuse 'time bomb' of cardiology
(University of Western Ontario) In a new study published in EBioMedicine, researchers at Western University and Lawson Health Research Institute use principles from cancer biology to demonstrate what might be causing aortic aneurysms and potentially how to treat them. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 25, 2019 Category: International Medicine & Public Health Source Type: news

USPSTF Addresses Screening for Abdominal Aortic Aneurysm
TUESDAY, June 18, 2019 -- The U.S. Preventive Services Task Force (USPSTF) recommendations on screening for abdominal aortic aneurysm (AAA) vary with sex, age, smoking status, and family history. These recommendations form the basis of a draft... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 18, 2019 Category: Pharmaceuticals Source Type: news

GMED Reinstates CE Mark for Endologix Nellix System
Endologix reported a huge regulatory win this week. The Irvine, CA-based company said its CE mark for the Nellix EndoVascular Aneurysm Sealing System has been reinstated, allowing the device to return to the European market. In January, Endologix initiated a voluntary recall of the existing inventory of its Nellix endovascular aneurysm sealing system. The company decided to limit the device to use under clinical protocol with pre-screened patients that adhere to the current indications. The company's CE mark for the Nellix system was subsequently suspended. Endologix said the reinstateme...
Source: MDDI - June 7, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

Visible public health leadership needed to boost vaccine coverage
(SAGE) Public health expert Professor John Ashton is calling for local directors of public health to provide visible leadership to address the recent systematic deterioration of vaccine coverage levels. Writing in the Journal of the Royal Society of Medicine, he describes recent falls in the uptake of other preventative programs, including bowel, breast and cervical cancer and aortic aneurysm. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 5, 2019 Category: Infectious Diseases Source Type: news

Long-Term Survival Similar for Endovascular, Open AAA Repair
WEDNESDAY, May 29, 2019 -- For patients with asymptomatic abdominal aortic aneurysm, long-term overall survival is similar with either endovascular repair or open repair, according to a study published in the May 30 issue of the New England Journal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 29, 2019 Category: Pharmaceuticals Source Type: news

Adult Health Screening
This report summarises evidence on the management of four screening programmes in England: bowel cancer, breast cancer, cervical cancer and abdominal aortic aneurysm. The report finds that the Department of Health and Social Care, NHS England and Public Health England are not doing enough to make sure that everyone who is eligible to take part in screening is doing so, and do not know if everyone who should be invited for screening has been (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 13, 2019 Category: Consumer Health News Source Type: news

Virtual reality engages patients more than CT, booklets
Patients with an abdominal aortic aneurysm were more engaged and had a better...Read more on AuntMinnie.comRelated Reading: 4 practical applications of VR, AR in radiology SIR: Virtual reality beats fluoroscopy for catheter placement VR, AR elevate radiologists' value in future of medicine Virtual reality may help plan, guide glioma resection VR software may increase MRI segmentation efficiency (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 25, 2019 Category: Radiology Source Type: news

You Can Cut Your Odds for an Aortic Aneurysm
Title: You Can Cut Your Odds for an Aortic AneurysmCategory: Health NewsCreated: 4/22/2019 12:00:00 AMLast Editorial Review: 4/23/2019 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - April 23, 2019 Category: Cardiology Source Type: news

You Can Cut Your Odds for an Aortic Aneurysm
MONDAY, April 22, 2019 -- People at risk for an aortic aneurysm should get screened for the life-threatening condition, an expert says. Aortic aneurysms are balloon-like bulges that can develop anywhere along the aorta, which runs from your heart... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 22, 2019 Category: General Medicine Source Type: news

Endologix readies for 1-for-10 reverse split
Endologix (NSDQ:ELGX) said yesterday that its board of directors set the ratio for its reverse stock split at 1-for-10. Beginning today, Endologix’s common stock will trade on the Nasdaq Global Select market on a reverse stock split-adjusted basis, the Irvine, Calif.-based company reported. Following the reverse split, there will be roughly 10.3 million shares of issued and outstanding common stock, according to Endologix. The company’s stock will continue to trade under the ‘ELGX’ ticker. In February, Endologix posted fourth-quarter and full-year results that missed sales and earnings estimate...
Source: Mass Device - March 6, 2019 Category: Medical Devices Authors: Sarah Faulkner Tags: Business/Financial News Featured Stent Grafts Wall Street Beat Endologix Source Type: news

InFocus: Aortic Aneurysm and Dissection Added to List of Fluoroquinolone Side Effects
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - March 1, 2019 Category: Emergency Medicine Tags: InFocus Source Type: news

Endologix misses the mark with Q4, 2018 numbers
The objectives we accomplished during the second half of 2018 align with those we laid out during our second-quarter earnings call as part of our strategic reset. As we enter 2019, our single biggest lever will be a consistent and unwavering application of individual and company-wide accountability. We will lean heavily on this lever throughout the year as the critical enabler of consistent delivery on our commitments to patients, customers, investors and other stakeholders. We are determined to sustain the momentum generated over the last two quarters as we continue to take steps to improve the company’s operational...
Source: Mass Device - February 27, 2019 Category: Medical Devices Authors: Brad Perriello Tags: MassDevice Earnings Roundup Stent Grafts Wall Street Beat Endologix Source Type: news

How Endologix Is Winning Customers Back One Procedure at a Time
Endologix might not be out of the woods yet, but the company does appear to be moving in the right direction. "We are shifting from a defensive position to an offensive position," CEO John Onopchenko said during the company's fourth-quarter earnings call on Monday, as transcribed by Seeking Alpha. The company reported sequential sales growth of its Ovation system in the fourth quarter, which management said gives them confidence that the platform will return Endologix to growth in the second half of 2019. But to fully appreciate that projection, investors have to look back at where the Irvine, CA-base...
Source: MDDI - February 26, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

Superior Survival With TEVAR vs Open Aortic Aneurysm Repair Superior Survival With TEVAR vs Open Aortic Aneurysm Repair
Endovascular repair is increasingly used instead of open surgery for descending thoracic aortic aneurysms. Now, a new study suggests that TEVAR should be the standard of care.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 21, 2019 Category: Consumer Health News Tags: Cardiology News Source Type: news

Why 20% of men ignore the test that'll stop them dropping dead?
Abdominal aortic aneurysm, or AAA, is a swelling of the body’s biggest blood vessel, the aorta, which runs directly from the heart to the lower body. If it bursts, 8 out of 10 victims die. (Source: the Mail online | Health)
Source: the Mail online | Health - February 10, 2019 Category: Consumer Health News Source Type: news

Why 20% of men ignore the test that'll stop them dropping dead?
Abdominal aortic aneurysm, or AAA, is a swelling of the body ’s biggest blood vessel, the aorta, which runs directly from the heart to the lower body. If it bursts, 8 out of 10 victims die. (Source: the Mail online | Health)
Source: the Mail online | Health - February 10, 2019 Category: Consumer Health News Source Type: news

ASK DR ELLIE: What can I do about my 2.3in aortic aneurysm which could rupture
I am an 81-year-old man and have recently been told I have an aortic aneurysm, a bulge in a major artery in my abdomen that measures 2.3in and could rupture. What can I do? (file image) (Source: the Mail online | Health)
Source: the Mail online | Health - February 2, 2019 Category: Consumer Health News Source Type: news