Major discovery in the genetics of Down syndrome
(University of Montreal) New research highlights the RCAN1 gene's effect on memory and learning. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 21, 2020 Category: Biology Source Type: news

Receiving the news of Down syndrome in the era of prenatal testing
(Massachusetts General Hospital) Most of the mothers of a child with Down Syndrome born in the Netherlands between 2010-16 have consciously chosen not to have prenatal testing. This may be considered as an informed choice, as the majority of these mothers felt that a child with DS was welcome in their family. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2020 Category: International Medicine & Public Health Source Type: news

Atypical Sleep Tied to Language Skills in Neurodevelopmental Disorders
Nighttime sleep duration predicted receptive vocabulary size in Down syndrome, Williams syndrome (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - February 4, 2020 Category: Psychiatry Tags: Neurology, Pediatrics, Psychiatry, Journal, Source Type: news

Atypical Sleep Tied to Language Skills in Neurodevelopmental Disorders
TUESDAY, Feb. 4, 2020 -- In children with fragile X syndrome (FXS), Down syndrome (DS), and Williams syndrome (WS), disrupted sleep may adversely affect language development, according to a study published in the February issue of Research in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 4, 2020 Category: Pharmaceuticals Source Type: news

Federal government backs Ohio on Down syndrome abortion law
The federal government is taking Ohio's side in a lawsuit over the state law prohibiting doctors from performing abortions based on a fetal diagnosis of Down syndrome (Source: ABC News: Health)
Source: ABC News: Health - January 22, 2020 Category: Consumer Health News Tags: Health Source Type: news

Sleep linked to language skills in neurodevelopmental disorders
(Anglia Ruskin University) New research has discovered that Down's syndrome, Fragile X syndrome and Williams syndrome are all linked to sleep disruption in very young children, and that sleep plays a crucial role in the development of these children's language skills. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 16, 2020 Category: Biology Source Type: news

The molecule that can AUTAC bad proteins
(Tohoku University) Tohoku University researchers have developed a strategy that could help cells get rid of disease-related debris. Further research could lead to treatments for neurodegenerative and metabolic diseases, Down syndrome, and maybe even aging-related diseases. The findings were published in the journal Molecular Cell. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 27, 2019 Category: International Medicine & Public Health Source Type: news

Some Down syndrome problems reversed in mice
In a mouse model of Down syndrome, blocking a cellular pathway in brain cells improved learning and memory. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - November 26, 2019 Category: Consumer Health News Source Type: news

Washington University gets $11.5M grant to study Down syndrome in babies
Washington University School of Medicine has received a five-year, $11.5 million grant from the National Institutes of Health to study brain development in babies with Down syndrome and how it differs from that in other babies. The study hopes this will lead to therapies to counter developmental delays in children with the condition, officials said. The grant is part of a $77 million initiative that started in 2018 to boost basic and clinical research on infants and children with Down syndrome.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 25, 2019 Category: Biotechnology Authors: Veneta Rizvic Source Type: news

Governor vetoes bill outlawing abortions over Down syndrome
Pennsylvania’s Democratic governor is vetoing a bill that would prohibit abortions because of a prenatal Down syndrome, a day after it passed the Republican-controlled Legislature (Source: ABC News: Health)
Source: ABC News: Health - November 21, 2019 Category: Consumer Health News Tags: Health Source Type: news

Three clinics rapped for misleading pregnant women
Three clinics have been rapped for misleading pregnant women by exaggerating the effectiveness of Down's Syndrome blood tests. The companies charge £650 per test. (Source: the Mail online | Health)
Source: the Mail online | Health - November 20, 2019 Category: Consumer Health News Source Type: news

MU researchers describe catatonia in Down syndrome
(University of Missouri-Columbia) Down syndrome, due to an extra chromosome 21, occurs in 250,000 children and adults in the United States, making it the country's most common chromosomal disorder. Inherited heart defects, thyroid cancer, celiac disease and developmental disabilities are common Down syndrome complications. Only recently has catatonia, a behavioral condition marked by new onset immobility, mutism, withdrawal and other behavioral abnormalities, been recognized in Down syndrome. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2019 Category: International Medicine & Public Health Source Type: news

Arthritis Risk Underestimated in Children With Down Syndrome Arthritis Risk Underestimated in Children With Down Syndrome
Arthritis can be missed in young people with Down syndrome, who might not effectively communicate their pain, so experts recommend annual screening.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 18, 2019 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Most Admired CEO Michelle Sie Whitten's for-profit biz experience informs nonprofit advocacy
Global Down Syndrome Foundation president and CEO was one of DBJ's very first Outstanding Women in Business through her work in the cable industry. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 15, 2019 Category: Biotechnology Authors: Jonathan Rose Source Type: news

In Down Syndrome mouse model, scientists reverse intellectual deficits with drugs
(University of California - San Francisco) In a surprising finding using the standard animal model of Down syndrome (DS), scientists were able to correct the learning and memory deficits associated with the condition -- the leading genetic cause of cognitive disability and the most frequently diagnosed chromosomal disorder in the US -- with drugs that target the body's response to cellular stresses. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 14, 2019 Category: Biology Source Type: news

Translating translation in Down syndrome
(Source: ScienceNOW)
Source: ScienceNOW - November 14, 2019 Category: Science Authors: Halliday, M., Mallucci, G. R. Tags: perspective Source Type: news

Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome
In this study, we found that the integrated stress response (ISR)—a signaling network that maintains proteostasis—was activated in the brains of DS mice and individuals with DS, reprogramming translation. Genetic and pharmacological suppression of the ISR, by inhibiting the ISR-inducing double-stranded RNA–activated protein kinase or boosting the function of the eukaryotic translation initiation factor eIF2-eIF2B complex, reversed the changes in translation and inhibitory synaptic transmission and rescued the synaptic plasticity and long-term memory deficits in DS mice. Thus, the ISR plays a crucial role ...
Source: ScienceNOW - November 14, 2019 Category: Science Authors: Zhu, P. J., Khatiwada, S., Cui, Y., Reineke, L. C., Dooling, S. W., Kim, J. J., Li, W., Walter, P., Costa-Mattioli, M. Tags: Cell Biology, Neuroscience r-articles Source Type: news

Study: Aging With Down Syndrome Means Huge Alzheimer's Risk
Title: Study: Aging With Down Syndrome Means Huge Alzheimer's RiskCategory: Health NewsCreated: 11/7/2019 12:00:00 AMLast Editorial Review: 11/8/2019 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - November 8, 2019 Category: Geriatrics Source Type: news

NHS changes guidance on Down's syndrome after accused of 'scaremongering'
Campaigners, including London actress Sally Phillips (pictured with her son Olly, 15) have now thanked for the NHS for amending the advice, which wasn't due to be revised until April. (Source: the Mail online | Health)
Source: the Mail online | Health - November 5, 2019 Category: Consumer Health News Source Type: news

Down Syndrome Carries Raised Risk of Dementia by 55
Title: Down Syndrome Carries Raised Risk of Dementia by 55Category: Health NewsCreated: 11/4/2019 12:00:00 AMLast Editorial Review: 11/5/2019 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - November 5, 2019 Category: Geriatrics Source Type: news

People with Down syndrome have trouble using smart speakers. Here's how Google's trying to help
Google and the Canadian Down Syndrome Society have launched a new project that is attempting to teach the tech giant’s systems to better understand people who speak differently. (Source: CBC | Health)
Source: CBC | Health - November 4, 2019 Category: Consumer Health News Tags: News/Canada/Toronto Source Type: news

Down Syndrome Carries Raised Risk of Dementia by 55
MONDAY, Nov. 4, 2019 -- Most people with Down syndrome have dementia by age 55, a new study shows. People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disabilities. Surviving to middle age... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 4, 2019 Category: General Medicine Source Type: news

Dementia Common in Down Syndrome Patients Aged & #8805;55
MONDAY, Nov. 4, 2019 -- More than half of individuals with Down syndrome aged 55 years or older have dementia claims and 32.7 percent have Alzheimer disease (AD) claims, according to a research letter published online Oct. 28 in JAMA Neurology. Eric... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 4, 2019 Category: Pharmaceuticals Source Type: news

Midwife helps with healthy delivery of high-risk child with Down Syndrome
“I had no idea what a midwife was.” Lauren Dantzler isn’t alone. A mother of three, Dantzler had sought out Atrium Health’s Piedmont GYN/OB-Rock Hill during her first pregnancy upon the advice of a friend. She’s since relied on the certified nurse-midwives (CNM) of Atrium Health to deliv er her children, which included a high-risk pregnancy with her youngest son, Copelan. Across four OB/GYN practices, Atrium Health offers midwifery care from 18 experienced midwives. “I sing their praises… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 1, 2019 Category: Biotechnology Authors: Atrium Health Source Type: news

High rates of dementia, Alzheimer ’s observed among older people with Down syndrome
NIH-funded study highlights need for research on aging Down syndrome population. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - October 28, 2019 Category: American Health Source Type: news

Ohio Ban on Down Syndrome Abortion Blocked by U.S. Appeals Court Ohio Ban on Down Syndrome Abortion Blocked by U.S. Appeals Court
A divided federal appeals court on Friday said Ohio cannot enforce a 2017 law banning abortions when medical tests show that a fetus has Down syndrome.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 15, 2019 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Ohio ban on Down syndrome abortion blocked by U.S. appeals court
A divided federal appeals court on Friday said Ohio cannot enforce a 2017 law banning abortions when medical tests show that a fetus has Down syndrome. (Source: Reuters: Health)
Source: Reuters: Health - October 12, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

New NIH grant awards boost funding for research on Down syndrome
INCLUDE project aims to address conditions of Down syndrome and apply knowledge to larger population. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 25, 2019 Category: American Health Source Type: news

‘ I Am Worried There Will Be Fewer Of Us, ’ Says Campaigner Against Down Syndrome Test
(CNN) — Natalie Dedreux has spent months campaigning against a plan to make a blood test for Down syndrome free in Germany. While its proponents say the prenatal test is a safer alternative to current procedures and should be available to everyone, Dedreux believes it will lead to people like her being “sorted out.” Dedreux, a 20-year aspiring journalist from Cologne, has the condition. “I am worried that if pregnant women find out their baby has Down syndrome, they will decide against us …. because they are scared,” she wrote on her blog. She has attended protests against the plan and ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 19, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Down Syndrome Source Type: news

'I am worried there will be fewer of us,' says campaigner against Down syndrome test
Natalie Dedreux has spent months campaigning against a plan to make a Down syndrome blood test free in Germany. While its proponents say the prenatal test is a safer alternative to current procedures and should be available to everyone, Dedreux believes it will lead to people like her being "sorted out." (Source: CNN.com - Health)
Source: CNN.com - Health - September 19, 2019 Category: Consumer Health News Source Type: news

'Oldest man' with Down's syndrome loves dancing
George Wildgust, 77, was not expected to live past the age of 10 when he was born. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 11, 2019 Category: Consumer Health News Source Type: news

Routine PET field-of-view enough for pediatric lymphoma
A routine "eyes to thighs" field-of-view with FDG-PET/CT scans is more than...Read more on AuntMinnie.comRelated Reading: Top 5 clinical applications of pediatric 3D printing SNMMI: Whole-body dynamic PET matches standard images SNMMI: PET spotlights link between Down syndrome, Alzheimer's NaF-PET/CT rarely finds prostate cancer metastases PET/MRI matches PET/CT with less radiation for children (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 5, 2019 Category: Radiology Source Type: news

Standing tall: feasibility of a modified ride-on car that encourages standing - Logan SW, Catena MA, Sabet A, Hospodar CM, Yohn H, Govindan A, Galloway JC.
PURPOSE: The purpose of this study was to determine the feasibility of infants with Down syndrome to use a modified ride-on car with seated and standing modes. METHODS: Participants included 4 infants with Down syndrome. Families were asked to prov... (Source: SafetyLit)
Source: SafetyLit - July 23, 2019 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Greater risk of metabolic disease in Down's syndrome
Dyslipidaemia and prediabetes are more common in young patients with Down's syndrome, according to a study published inPediatrics.Medscape (Source: Society for Endocrinology)
Source: Society for Endocrinology - July 19, 2019 Category: Endocrinology Source Type: news

Dyslipidemia, Prediabetes More Common in Youth With Down Syndrome Dyslipidemia, Prediabetes More Common in Youth With Down Syndrome
Children and young adults with Down syndrome (DS) have a greater prevalence of abnormal lipid levels and prediabetes compared to typically-developing youth, for the same amount of body fat, according to a study online today in Pediatrics.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 18, 2019 Category: Consumer Health News Tags: Pediatrics News Source Type: news

BU researcher receives NIH grant to study Down syndrome
(Boston University School of Medicine) Tarik F. Haydar, PhD, professor of anatomy and neurobiology at Boston University School of Medicine (BUSM), has been awarded a two-year Exploratory/Developmental Research Grant Award (R21) from the National Institutes of Health (NIH). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2019 Category: International Medicine & Public Health Source Type: news

Effect of core stability exercises and treadmill training on balance in children with Down Syndrome: randomized controlled trial - Alsakhawi RS, Elshafey MA.
INTRODUCTION: Core stability exercises and treadmill training play a crucial role in physical therapy interventions and have an effect on balance in children with Down Syndrome (DS); however, whether core stability exercises or treadmill training has more ... (Source: SafetyLit)
Source: SafetyLit - July 15, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

New study discovers genetic changes linked to leukaemia in children with down's syndrome
(University of Oxford) Researchers at the University of Oxford, in collaboration with colleagues from Hannover Medical School and Martin-Luther-University Halle-Wittenberg, have discovered the specific gene mutations that are required for the development of leukaemia in children with Down's syndrome. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 11, 2019 Category: Cancer & Oncology Source Type: news

New study discovers genetic changes linked to leukemia in children with Down syndrome
(University of Oxford) Researchers at the University of Oxford, in collaboration with colleagues from Hannover Medical School and Martin-Luther-University Halle-Wittenberg, have discovered the specific gene mutations that are required for the development of leukemia in children with Down syndrome. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 11, 2019 Category: Cancer & Oncology Source Type: news

PET/MRI can pinpoint causes of chronic extremity pain
FDG-PET can help boost the detection of abnormalities associated with complex...Read more on AuntMinnie.comRelated Reading: SNMMI: Whole-body dynamic PET matches standard images SNMMI: PET spotlights link between Down syndrome, Alzheimer's SNMMI: PET ligand can diagnose brain disorder before autopsy SNMMI: Technetium radiotracer tracks rheumatoid arthritis SNMMI: FDG-PET/MRI improves pain diagnosis, management (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 3, 2019 Category: Radiology Source Type: news

SNMMI: Whole-body dynamic PET matches standard images
ANAHEIM, CA - Researchers from the University of Wisconsin-Madison developed...Read more on AuntMinnie.comRelated Reading: Video from SNMMI 2019: Dr. Barry Siegel on PET reimbursement SNMMI: PET spotlights link between Down syndrome, Alzheimer's SNMMI: PET ligand can diagnose brain disorder before autopsy SNMMI: Technetium radiotracer tracks rheumatoid arthritis SNMMI: FDG-PET/MRI improves pain diagnosis, management (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 27, 2019 Category: Radiology Source Type: news

SNMMI: PET tracks smoking's toll on immune system
Smoking tobacco takes a heavy toll on the immune system --a toll that can be...Read more on AuntMinnie.comRelated Reading: SNMMI: PET spotlights link between Down syndrome, Alzheimer's SNMMI: PET ligand can diagnose brain disorder before autopsy SNMMI: Technetium radiotracer tracks rheumatoid arthritis SNMMI: FDG-PET/MRI improves pain diagnosis, management SNMMI: PSMA-PET helps guide prostate cancer therapy (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 26, 2019 Category: Radiology Source Type: news

Video from SNMMI 2019: Alan Packard on molybdenum supply
ANAHEIM, CA - Supplies of molybdenum have been stable for the past few months,...Read more on AuntMinnie.comRelated Reading: Video from SNMMI 2019: Dr. Francois Lamoureux on access to PET Video from SNMMI 2019: Dr. Barry Siegel on PET reimbursement Video from SNMMI 2019: Outreach needed to tell discipline's story SNMMI: PET spotlights link between Down syndrome, Alzheimer's SNMMI: FDG-PET/MRI improves pain diagnosis, management (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 26, 2019 Category: Radiology Source Type: news

SNMMI: PET spotlights link between Down syndrome, Alzheimer's
ANAHEIM, CA - Researchers are reporting early success in adapting a new method...Read more on AuntMinnie.comRelated Reading: PiB-PET study strengthens link between amyloid, dementia High amyloid levels on PET may indicate early Alzheimer's PiB-PET could open window on common meningiomas SNMMI: PET shows tau may be Alzheimer's catalyst SNMMI: PiB-PET finds unique Down syndrome trait (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 25, 2019 Category: Radiology Source Type: news

This is what the Left has become: Targeting retarded children for transgender indoctrination
(Natural News) The latest perverse fetish of the lesbian, gay, bisexual, transgender, queer, and pedophile (LGBTQP) cult is to prey on young children with mental disabilities, including little ones with Down syndrome or autism, and exploit them as transgender drag queens for sexual entertainment. During a recent episode of “The Alex Jones Show,” InfoWars host... (Source: NaturalNews.com)
Source: NaturalNews.com - June 9, 2019 Category: Consumer Health News Source Type: news

Maternal blood test is effective for Down syndrome screening in twin pregnancies
(Wiley) Cell-free DNA (cfDNA) testing, which involves analyzing fetal DNA in a maternal blood sample, is a noninvasive and highly accurate test for Down syndrome in singleton pregnancies, but its effectiveness in twin pregnancies has been unclear. A new analysis published in Ultrasound in Obstetrics& Gynecology reveals that cfDNA testing for Down syndrome in twins is just as effective as in singletons, with a detection rate of 98% and only a 0.05% rate of misdiagnosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 5, 2019 Category: International Medicine & Public Health Source Type: news

UC Davis researcher looks to cannabis compound to treat developmental disorders
Dr. Randi Hagerman is on the front lines of developing new treatments for kids with autism, Down syndrome and other developmental disorders. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - May 24, 2019 Category: Biotechnology Authors: Felicia Alvarez Source Type: news

Do exercise interventions improve balance for children and adolescents with Down syndrome? A systematic review - Ma ïano C, Hue O, Lepage G, Morin AJS, Tracey D, Moullec G.
BACKGROUND: Youths with Down syndrome are characterized by deficits in balance/postural stability. One way to palliate balance deficits among this population is through exercise interventions. However, to the authors' knowledge, the effects of exercise int... (Source: SafetyLit)
Source: SafetyLit - May 18, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Pennsylvania House tries anew to ban Down syndrome abortions
Pennsylvania's House of Representatives is launching another effort to outlaw abortions because of a prenatal diagnosis of Down syndrome, although it faces a veto if it even reaches Democratic Gov. Tom Wolf's desk (Source: ABC News: Health)
Source: ABC News: Health - May 15, 2019 Category: Consumer Health News Tags: Health Source Type: news

Weight-Loss Surgery Just as Successful for Teens With Down Syndrome
Title: Weight-Loss Surgery Just as Successful for Teens With Down SyndromeCategory: Health NewsCreated: 4/19/2019 12:00:00 AMLast Editorial Review: 4/22/2019 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - April 22, 2019 Category: Pediatrics Source Type: news