Why human egg cells don't age well
(RIKEN) When egg cells form with an incorrect number of chromosomes -- a problem that increases with age -- the result is usually a miscarriage or a genetic disease such as Down syndrome. A new study published in nature Communications shows how researchers at the RIKEN Center for Developmental Biology in Japan have pinpointed a significant cellular event that leads to these types of age-related chromosomal errors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 1, 2015 Category: Global & Universal Source Type: news

Report warns of threat to unborn babies from CMV virus
"Thousands of pregnant women are unwittingly passing on infections to their unborn babies that cause severe disabilities," is the headline in the Daily Mail after a new report highlighted the risks cytomegalovirus (CMV) can pose to pregnancies. The paper says cytomegalovirus "can lie dormant in mother's body for years" and "is caught from other children through nappy changing and wiping mouths", so often older siblings can pass it on to unborn babies.  What is the basis for this report? The story was prompted by the release of a report by the charity CMV Action. The ch...
Source: NHS News Feed - June 30, 2015 Category: Consumer Health News Tags: Pregnancy/child QA articles Source Type: news

Lab-grown blood, artificial organs – the science transforming our health
After the news that scientists have developed blood that can be grown in a laboratory, here are more discoveries that are redefining medicineThe news that scientists have developed blood that can be grown in the laboratory raised hope last week that a powerful weapon had been created to tackle disease. Ensuring that sufficient blood is donated to hospitals is a constant problem for medical services and any new source is to be welcomed, doctors acknowledged. In addition, the prospect that blood could be grown artificially from stem cells suggests a promising new approach could be taken in helping patients with thalassaemia ...
Source: Guardian Unlimited Science - June 28, 2015 Category: Science Authors: Robin McKie Science editor Tags: Medical research Health Science Cancer Heart attack Parkinson's disease Malaria Down's syndrome Source Type: news

Alzheimer's disease works differently in patients with and without Down Syndrome, study shows
A study revealed differences in the way brain inflammation -- considered a key component of AD-- is expressed in different subsets of patients, in particular people with Down syndrome (DS) and AD. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 25, 2015 Category: Science Source Type: news

Alzheimer's disease works differently in patients with and without Down syndrome
(University of Kentucky) Researchers at the University of Kentucky's Sanders-Brown Center on Aging have completed a study that revealed differences in the way brain inflammation -- considered a key component of Alzheimer's disease -- is expressed in different subsets of patients, in particular people with Down syndrome and AD. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 25, 2015 Category: Global & Universal Source Type: news

VIDEO: Sister's quest for Down's death inquest
The sister of a woman with Down's Syndrome who died in hospital has gone to the High Court to try to overturn a coroner's decision not to allow a full inquest into her death. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - June 24, 2015 Category: Consumer Health News Source Type: news

MRI offers insight into Down syndrome
Using MRI, researchers at Drexel University discovered a thicker cerebral cortex (more) (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 24, 2015 Category: Radiology Source Type: news

Boy With Down Syndrome Tells His Dad He's 'Doing A Great Job' For Father's Day
Father's Day is a time to celebrate and express gratitude to dads, including dads of children with special needs. Told from the perspective of a boy with Down syndrome, this sweet video from the Jerome Lejeune Foundation is a moving tribute to his loving father who is smart, silly and supportive. "I wanted to tell you," the boy says, "You are doing a great job!" So sweet. @media only screen and (min-width : 500px) {.ethanmobile { display: none; }} Like Us On Facebook | Follow Us On Twitter | Contact HuffPost Parents -- This feed and its contents are the property of The Huffington Post, and use i...
Source: Healthy Living - The Huffington Post - June 19, 2015 Category: Consumer Health News Source Type: news

Thick cortex could be key in Down syndrome
The thickness of the brain's cerebral cortex could be a key to unlocking answers about intellectual development in youth with Down syndrome. It could also provide new insights to why individuals with this genetic neurodevelopmental disorder are highly susceptible to early onset Alzheimer's disease later in life. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 19, 2015 Category: Science Source Type: news

Wagga Wagga boy Henry Pavitt, with Down Syndrome, plays Football4All in NSW
Henry Pavitt, six, from Wagga Wagga, has Down syndrome, congenital heart disease, is tiny for his age and requires regular surgery on his main aorta. (Source: the Mail online | Health)
Source: the Mail online | Health - June 19, 2015 Category: Consumer Health News Source Type: news

Thick cortex could be key in Down syndrome
(Drexel University) The thickness of the brain's cerebral cortex could be a key to unlocking answers about intellectual development in youth with Down syndrome. It could also provide new insights to why individuals with this genetic neurodevelopmental disorder are highly susceptible to early onset Alzheimer's disease later in life. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 19, 2015 Category: Global & Universal Source Type: news

Single Father Photographs The Complexities Of Raising A Daughter With Disabilities
Being a parent is a challenge no matter what. Being a single parent, of course, requires even more responsibility and sacrifice. Being a single parent to a child facing severe intellectual disabilities, however, is a trial few among us could even imagine. Leon Borensztein, a Polish-born photographer and single father, lived this challenging tale. He began photographing his daughter, Sharon, before she was born. Now, approximately 30 years later, he's still going. Soon after Sharon's birth, Leon and his former wife could sense something wasn't right. After months of testing, the various diagnoses began to roll in: blind...
Source: Science - The Huffington Post - June 17, 2015 Category: Science Source Type: news

Mom's Facebook post on Down syndrome goes viral
Mother of a 4-month-old girl with Down syndrome wants people to know what not to say (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - June 10, 2015 Category: Consumer Health News Source Type: news

'United We Feed' Photo Series Supports All Moms -- However They Nourish Their Children
Photographer and mom of two Caitlin Domanico hopes her latest project will provide support for all parents navigating the world of pumping, nursing and bottle feeding. "United We Feed" is a series of photos Domanico took of clients, friends, and acquaintances nourishing their babies in the manner that is best for their individual families. For many of the women, that's breastfeeding. For others, it's pumping and bottle feeding. And for some, it's tube feeding. "Everybody's journey is so different," the photographer told The Huffington Post. "I love being able to tell their story and hopefully c...
Source: Healthy Living - The Huffington Post - June 8, 2015 Category: Consumer Health News Source Type: news

Study examines psychotropic medication use in children, teens with Down syndrome
A new study gives insight into the mental health of children and teens with Down syndrome and the behavioral medications that medical caregivers sometimes prescribe for them. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 8, 2015 Category: Science Source Type: news

Study examines psychotropic medication use in children, teens with Down syndrome
(Cincinnati Children's Hospital Medical Center) A new study gives insight into the mental health of children and teens with Down syndrome and the behavioral medications that medical caregivers sometimes prescribe for them. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 8, 2015 Category: Global & Universal Source Type: news

Breakthrough Down's syndrome test could prevent HUNDREDS of miscarriages
A NON-INVASIVE screening test that could save around 300 unborn babies could now make its way onto the NHS (Source: Daily Express - Health)
Source: Daily Express - Health - June 6, 2015 Category: Consumer Health News Source Type: news

Blood test for Down's syndrome may save babies
Simple test could prevent hundreds of women losing their babies during invasive procedure (Source: Telegraph Health)
Source: Telegraph Health - June 6, 2015 Category: Consumer Health News Source Type: news

New Down's syndrome blood test 'would cut miscarriage risk'
Experts believe a new non-invasive Down's syndrome test which could soon be available on the NHS would radically change pregnancy screening (Source: Telegraph Health)
Source: Telegraph Health - June 6, 2015 Category: Consumer Health News Tags: test scan pregnancy baby pregnant chromosome ultrasound amniocentesis Down's syndrome Source Type: news

Down's blood test 'would cut risk'
A blood test for Down's syndrome can reduce the number of pregnant women needing risky tests, say UK doctors. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - June 6, 2015 Category: Consumer Health News Source Type: news

Noninvasive prenatal fetal testing can detect early stage cancer in mothers
(European Society of Human Genetics) Noninvasive prenatal testing (NIPT) for chromosomal fetal disorders is used increasingly to test for conditions such as Down's syndrome, because it is known to be much safer than invasive testing methods. Now, for the first time, researchers from Belgium have found another advantage of NIPT; it can detect maternal cancers at an early stage, before symptoms appear. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 5, 2015 Category: Global & Universal Source Type: news

First national study of noninvasive prenatal testing shows it works
(European Society of Human Genetics) Results from the first national study of noninvasive prenatal testing in women at high risk of having a baby with Down's syndrome, carried out in The Netherlands, show that the technique is accurate and acceptable to parents. The researchers involved now believe that such testing should be available to all women, irrespective of their risk of having an affected child. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 5, 2015 Category: Global & Universal Source Type: news

To Your Health: NLM update: Are genetic tests more precise than standard screening?
Listen to the To Your Health: NLM update on Are genetic tests more precise than standard screening?. The transcript is also available. A genetic test is more clinically precise than standard screening for Down's syndrome and two other types of trisomy among pregnant women, finds a rare, comparative study recently published in New England Journal of Medicine. (Source: What's New on MedlinePlus)
Source: What's New on MedlinePlus - May 29, 2015 Category: Consumer Health News Source Type: news

Cancer drugs may hold key to treating Down syndrome and other brain disorders
(University of Michigan) A class of FDA-approved cancer drugs may be able to prevent problems with brain cell development associated with disorders including Down syndrome and Fragile X syndrome, researchers at the University of Michigan Life Sciences Institute have found. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 19, 2015 Category: Biology Source Type: news

[Editors' Choice] Excited by GABA
In a model of Down syndrome, signaling through GABAA receptors is excitatory rather than inhibitory. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - May 13, 2015 Category: Science Authors: Nancy Gough (mailto:ngough at aaas.org) Source Type: news

Cause of regression in individuals with down syndrome identified
Down syndrome, the most common chromosomal disorder in America, can be complicated by significant deterioration in movement, speech and functioning in some adolescents and young adults. Physicians previously attributed this regression to depression or early-onset Alzheimer's, and it has not responded to treatments. Now, a researcher has found that Catatonia, a treatable disorder, may cause regression in patients with Down syndrome. Individuals with regressive Down syndrome who were treated for Catatonia showed improvement, the researcher found. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 12, 2015 Category: Science Source Type: news

Cause of regression in individuals with down syndrome identified
(University of Missouri-Columbia) Down syndrome, the most common chromosomal disorder in America, can be complicated by significant deterioration in movement, speech and functioning in some adolescents and young adults. Physicians previously attributed this regression to depression or early-onset Alzheimer's, and it has not responded to treatments. Now, a researcher at the University of Missouri has found that Catatonia, a treatable disorder, may cause regression in patients with Down syndrome. Individuals with regressive Down syndrome who were treated for Catatonia showed improvement, the researcher found. (Source: EurekA...
Source: EurekAlert! - Medicine and Health - May 12, 2015 Category: Global & Universal Source Type: news

VIDEO: 'It's hard to get a job with Down's'
People living with Down's syndrome tell Victoria Derbyshire there are still too many barriers to finding a job. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 8, 2015 Category: Consumer Health News Source Type: news

Finding work with Down's syndrome
The struggle to find work with Down's syndrome (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 8, 2015 Category: Consumer Health News Source Type: news

Video captures girl with Down syndrome's reaction to cheerleading squad spot
10-year-old Lacey Parker of Stonewall, Louisiana tried out for the cheerleading squad at North DeSoto Middle School, and was overjoyed when she found out she made the squad. (Source: the Mail online | Health)
Source: the Mail online | Health - May 7, 2015 Category: Consumer Health News Source Type: news

Penn team finds protein 'cement' that stabilizes the crossroad of chromosomes
(University of Pennsylvania School of Medicine) A new study describes how the centromere is stabilized during replication. The structure and biology of the centromere is of considerable scientific interest because problems with it can lead to abnormalities in the chromosomes of daughter cells, which are the basis of such disorders as Down syndrome. As it turns out, the centromere is distinguished not only by its DNA sequence but also by a special type of nucleosome, which includes a protein called CENP-A. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 7, 2015 Category: Cancer & Oncology Source Type: news

New Prenatal DNA Test For Down Syndrome Dramatically Reduces Errors
A new prenatal DNA test detects Down syndrome with near 100% sensitivity, and a false positive rate almost 100% times lower than today's standard tests. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - April 26, 2015 Category: Pharmaceuticals Authors: Steven Salzberg Source Type: news

MIT receives $1.7 million for study of Down syndrome from Alana Foundation
(Massachusetts Institute of Technology) MIT's Picower Institute is to partner on four projects with Case Western Reserve University. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 22, 2015 Category: Global & Universal Source Type: news

Mom's Disney Photos Prove 'The Only Disability In Life Is Having A Bad Attitude'
If this isn't Disney magic in action, what is? Florida mom Kristina Bewley started taking her daughter Giselle to Disney World in September 2014. The 4-year-old loves all things Disney, from the princesses to Pixar characters to Wreck-It Ralph, Baymax and all the Tinkerbell movies, her mom told The Huffington Post. Giselle, an outgoing and headstrong little girl, has Down syndrome, and she loves going to Disney World in character costumes that her mom sews. As her daughter lives it up at the theme park, mom Kristina -- a photographer who works with kids with special needs -- takes photos of Giselle in her homemade costum...
Source: Healthy Living - The Huffington Post - April 21, 2015 Category: Consumer Health News Source Type: news

Brain Scans Give Clues to Link Between Alzheimer's, Down Syndrome
Title: Brain Scans Give Clues to Link Between Alzheimer's, Down SyndromeCategory: Health NewsCreated: 4/17/2015 12:00:00 AMLast Editorial Review: 4/20/2015 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - April 20, 2015 Category: Geriatrics Source Type: news

Brain Scans Give Clues to Link Between Alzheimer's, Down Syndrome
People with Down syndrome are at much higher risk of developing dementia, researchers say Source: HealthDay Related MedlinePlus Pages: Alzheimer's Disease, Diagnostic Imaging, Down Syndrome (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 17, 2015 Category: Consumer Health News Source Type: news

Teen With Down Syndrome's Reaction to Getting 1st Job Will Make You Smile
Ben Sunderman waited for days for his acceptance letter. (Source: ABC News: Health)
Source: ABC News: Health - April 17, 2015 Category: Consumer Health News Tags: Health Source Type: news

Fetal DNA in Mom's Blood Signals Down Syndrome (CME/CE)
(MedPage Today) -- Test is accurate for trisomy 21, but maybe less so for other genetic defects. (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 2, 2015 Category: OBGYN Source Type: news

Blood test beats standard screening for Down syndrome
Maternal blood testing of DNA more effectively screens for Down syndrome in (more) (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 2, 2015 Category: Radiology Source Type: news

New Down’s syndrome test more accurate than current screening
Conclusion This large study has shown that the new cfDNA test is better than current standard screening at detecting three trisomy conditions during pregnancy. The confidence in accurately identifying affected pregnancies was strongest for Down’s syndrome. There were much wider confidence intervals for the other two conditions. The cfDNA test was not 100% accurate, as there were false positive results for each condition, though much fewer than with standard screening. Around 3% of the cfDNA tests did not produce a result. Careful consideration and further research may be needed to decide the best approach in these c...
Source: NHS News Feed - April 2, 2015 Category: Consumer Health News Tags: Genetics/stem cells Medical practice Pregnancy/child Source Type: news

London hospitals set to offer 'more accurate' Down's Syndrome test
A group of NHS hospitals in London are in discussions to use a new non-invasive prenatal test for Down’s Syndrome that has been proven to be more accurate than other forms of testing for the condition. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - April 2, 2015 Category: Nursing Source Type: news

Newer Test for Down Syndrome Called 'Major Advance'
Title: Newer Test for Down Syndrome Called 'Major Advance'Category: Health NewsCreated: 4/1/2015 12:00:00 AMLast Editorial Review: 4/2/2015 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - April 2, 2015 Category: Pediatrics Source Type: news

Fetal DNA tests prove highly accurate but experts warn of exceptions
CHICAGO (Reuters) - A Roche blood test to screen fetuses for Down syndrome worked far better than standard prenatal screening tests in younger, low-risk women, U.S. researchers said on Wednesday, setting the stage for more widespread use. (Source: Reuters: Health)
Source: Reuters: Health - April 2, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Newer Test for Down Syndrome Called 'Major Advance'
But it won't eliminate need for invasive diagnostics such as amniocentesis, doctors say (Source: WebMD Health)
Source: WebMD Health - April 2, 2015 Category: Consumer Health News Source Type: news

Blood test for Down's syndrome hailed
Testing a pregnant woman's blood for disorders in her unborn child promises 'dramatic' advances in medicine, say researchers. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - April 2, 2015 Category: Consumer Health News Source Type: news

People with Down syndrome sit for stunning portraits
(Source: CNN.com - Health)
Source: CNN.com - Health - April 1, 2015 Category: Consumer Health News Source Type: news

Nigeria: Govts, Others Must Support People With Down Syndrome
[Independent (Lagos)] The Down Syndrome Foundation of Nigeria (DSFN) has urged government at all levels, corporate organisations and individuals to provide support for people with Down syndrome in the country. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 31, 2015 Category: African Health Source Type: news

Position statement on non-invasive prenatal screening issued
Two professional societies of human geneticists have issued a position statement on the promise and challenges of non-invasive prenatal testing, a procedure to test blood drawn from pregnant mothers for Down syndrome and other chromosomal disorders in the fetus. The document addresses the current scope of and future improvements in NIPT technology, ways it may fit with existing prenatal screening protocols, options and priorities in implementation, and associated social and ethical issues. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 25, 2015 Category: Science Source Type: news

ASHG and ESHG issue position statement on non-invasive prenatal screening
(American Society of Human Genetics) Two professional societies of human geneticists have issued a position statement on the promise and challenges of non-invasive prenatal testing, a procedure to test blood drawn from pregnant mothers for Down syndrome and other chromosomal disorders in the fetus. The document addresses the current scope of and future improvements in NIPT technology, ways it may fit with existing prenatal screening protocols, options and priorities in implementation, and associated social and ethical issues. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 25, 2015 Category: Global & Universal Source Type: news

11-year-old raised over £400 for twin with Down Syndrome by selling his toys
Jason Clark, from Barnsley, South Yorkshire, is a high-achieving 11-year-old, and his twin Aaron suffers from Down Syndrome and is deaf. Jason is raising money for his brother's education. (Source: the Mail online | Health)
Source: the Mail online | Health - March 23, 2015 Category: Consumer Health News Source Type: news