Impel NeuroPharma readies trial for intranasal drug-device migraine treatment
Impel NeuroPharma said today that the FDA gave it the green light to proceed with its Phase III clinical trial of INP104 – a drug delivered by Impel’s intranasal delivery device for the treatment of acute migraine. The company expects to start enrolling patients in the pivotal trial in the second half of this year. The study is designed to assess the safety and tolerability of long-term, intermittent use of the drug-device combination therapy. Get the full story at our sister site, Drug Delivery Business News. The post Impel NeuroPharma readies trial for intranasal drug-device migraine treatment appeared f...
Source: Mass Device - June 22, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Drug-Device Combinations Neurological Pharmaceuticals Regulatory/Compliance Impel Neuropharma Source Type: news

Eptinezumab Safe, Effective for Migraine Prevention Eptinezumab Safe, Effective for Migraine Prevention
A single dose of eptinezumab, which targets calcitonin gene-related peptide, provides rapid efficacy lasting up to 3 months in the prevention of chronic migraine, say PROMISE-2 investigators.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 21, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Medical News Today: What does having both chest pain and headache mean?
When someone has chest pain and a headache at the same time, the causes are usually unrelated. However, some conditions can cause both symptoms. We explain these conditions here. We also discuss when chest pain and a headache might be due to issues relating to the heart or blood pressure, and when to see a doctor. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 19, 2018 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

7 Weird Things That Could Be Triggering Migraines
Plus, what you can do about them. (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - June 19, 2018 Category: Consumer Health News Source Type: news

Why ARE migraines being treated with a drug linked to birth defects?
Valproate can be a very effective drug for treating epilepsy and bipolar disorder, but it can have serious detrimental effects on a foetus.Yet it remains widely-prescribed... (Source: the Mail online | Health)
Source: the Mail online | Health - June 18, 2018 Category: Consumer Health News Source Type: news

ASK THE GP: Help, I've got a white furry tongue!
DR MARTIN SCURR, the Daily Mail's resident GP, answers questions about a the migraines and the bizarre case of a white, furry, ulcerated tongue. (Source: the Mail online | Health)
Source: the Mail online | Health - June 18, 2018 Category: Consumer Health News Source Type: news

Migraines cost the economy  £3.3 billion a year
Researchers from Novartis, Paris, found that sufferers need up to 33 days off work a year to cope with their condition. Over 38 million people in the US and six million in the UK suffer migraines. (Source: the Mail online | Health)
Source: the Mail online | Health - June 18, 2018 Category: Consumer Health News Source Type: news

Teva late-stage headache trial fails
Teva announced it will discontinue a phase 3 trial testing fremanezumab for the treatment of chronic cluster headache. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - June 18, 2018 Category: Pharmaceuticals Source Type: news

What Does'The Incredibles 2' Have To Do With Migraines Or Seizures?
Concerns about some flashy scenes in The Incredibles 2 movie hit social media, and Disney issued a warning for moviegoers with epilepsy. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 18, 2018 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news

Teva to discontinue study for chronic headache treatment
(Reuters) - Israel's Teva Pharmaceutical Inc said on Friday it would discontinue a trial testing its drug for the treatment of chronic cluster headache, after an analysis showed that the drug was unlikely to meet the study's main goal. (Source: Reuters: Health)
Source: Reuters: Health - June 15, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

High blood pressure symptoms: Avoid ordering this at the pub to control your reading
HIGH blood pressure symptoms are not always easy to detect, but if signs do show you may experience a severe headache, an irregular heartbeat and difficulty breathing. Drinking too much alcohol can have a negative impact on your reading - and there ’s one thing you should definitely avoid ordering when you’re at the pub. (Source: Daily Express - Health)
Source: Daily Express - Health - June 13, 2018 Category: Consumer Health News Source Type: news

Vestibular Migraine and Janet Jackson
Title: Vestibular Migraine and Janet JacksonCategory: Doctor's& Expert's views on SymptomsCreated: 10/15/2008 12:00:00 AMLast Editorial Review: 6/13/2018 2:55:10 PM (Source: MedicineNet Migraine General)
Source: MedicineNet Migraine General - June 13, 2018 Category: Neurology Source Type: news

Headache: Questions To Ask Your Doctor About Headaches
Title: Headache: Questions To Ask Your Doctor About HeadachesCategory: Doctor's& Expert's views on SymptomsCreated: 7/15/2005 12:00:00 AMLast Editorial Review: 6/13/2018 2:55:06 PM (Source: MedicineNet Migraine General)
Source: MedicineNet Migraine General - June 13, 2018 Category: Neurology Source Type: news

Cryo-EM reveals interaction between major drug targets
(Van Andel Research Institute) For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects for conditions ranging from migraine to cancer. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 13, 2018 Category: Biology Source Type: news

Control of spreading depression with electrical fields - Whalen AJ, Xiao Y, Kadji H, Dahlem MA, Gluckman BJ, Schiff SJ.
Spreading depression or depolarization is a large-scale pathological brain phenomenon related to migraine, stroke, hemorrhage and traumatic brain injury. Once initiated, spreading depression propagates across gray matter extruding potassium and other activ... (Source: SafetyLit)
Source: SafetyLit - June 12, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

How I beat the misery of migraine
FIFTEEN years ago I suffered from migraines that racked every inch of my head and seemed to last eight days a week. I felt as if an eagle held my head in its talons or that the inside of my skull was studded with spikes. (Source: Daily Express - Health)
Source: Daily Express - Health - June 12, 2018 Category: Consumer Health News Source Type: news

Allergan oral migraine drug succeeds in study
(Reuters) - Allergan Plc said on Monday its oral migraine drug met the main goal across all doses in a study, with a statistically significant reduction in monthly headache days in patients with episodic migraine. (Source: Reuters: Health)
Source: Reuters: Health - June 11, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Pharmacotherapy for persistent posttraumatic headaches in children and adolescents: a brief review of the literature - Kacperski J.
Concussion, now most often referred to as mild traumatic brain injury in recent literature, is common in pediatrics, and headache is often the most common complaint post-injury. Although most children and adolescents recover within 1-2  weeks, some develop... (Source: SafetyLit)
Source: SafetyLit - June 11, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

High blood pressure symptoms: Drink this red juice daily to help control your reading
HIGH blood pressure symptoms can go unnoticed, but signs to be aware of include a severe headache, an irregular heartbeat and difficulty breathing. One of the best ways to control and prevent the condition is to eat a healthy, balanced diet - and drinking a specific juice can help regulate your reading. (Source: Daily Express - Health)
Source: Daily Express - Health - June 11, 2018 Category: Consumer Health News Source Type: news

Prevalence and pattern of helmet-induced headache among Danish military personnel - Rahmani Z, Kochanek A, Astrup JJ, Poulsen JN, Gazerani P.
Aims Headache is a leading reason to seek medical care. Several subtypes of headaches have been defined, one of which is external compression headache. This headache is due to an external physical compression applied on the head. It affects approximately 4... (Source: SafetyLit)
Source: SafetyLit - June 9, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Many Migraine Sufferers Skip Effective Behavioral Treatment Many Migraine Sufferers Skip Effective Behavioral Treatment
Even when a headache specialist refers migraine patients for proven behavioral treatments like biofeedback, relaxation training or cognitive behavioral therapy, barely half of them go, suggests a small U.S. study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 8, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Many migraine sufferers skip effective behavioral treatment
(Reuters Health) - Even when a headache specialist refers migraine patients for proven behavioral treatments like biofeedback, relaxation training or cognitive behavioral therapy, barely half of them go, suggests a small U.S. study. (Source: Reuters: Health)
Source: Reuters: Health - June 7, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Specialists Debate Naloxone White Paper: Pain Medicine News Report
(MedPage Today) -- Also, nerve block safe for treating migraine pain in pregnant women? (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - June 7, 2018 Category: Psychiatry Source Type: news

Migraine Breakthrough: Not So Fast
Many experts believe the approval of Aimovig marks the dawn of a new era in the treatment of chronic sufferers of migraine. For some sufferers it is, but for the majority it is not. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 7, 2018 Category: Pharmaceuticals Authors: Joshua Cohen, Contributor Source Type: news

Looking Forward at Migraine Meds and'Backwards' at Lumbar Punctures Looking Forward at Migraine Meds and'Backwards' at Lumbar Punctures
From the AAN 2018 Annual Meeting, Dr Deborah Friedman on the latest advances in migraine management, and more.American Headache Society and Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 6, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery Expert Interview Source Type: news

Non-Drug Migraine Treatments Often Ignored
Previous studies have shown that treatments such as cognitive behavioral therapy, stress management, relaxation techniques and biofeedback may reduce migraine symptoms by 50 percent or more. (Source: WebMD Health)
Source: WebMD Health - June 5, 2018 Category: Consumer Health News Source Type: news

Non - Drug Migraine Treatments Often Ignored
(Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - June 5, 2018 Category: Psychiatry Tags: Family Medicine, Neurology, Nursing, Psychiatry, Alternative Medicine, News, Source Type: news

Non-Drug Migraine Treatments Often Ignored
TUESDAY, June 5, 2018 -- Many migraine sufferers skip recommended behavioral treatments, such as stress management and talk therapy, a new study finds. Lack of time, cost and skepticism are among the reasons why, said Dr. Mia Minen, director of... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 5, 2018 Category: General Medicine Source Type: news

Non-Drug Migraine Treatments Often Ignored
Title: Non-Drug Migraine Treatments Often IgnoredCategory: Health NewsCreated: 6/5/2018 12:00:00 AMLast Editorial Review: 6/5/2018 12:00:00 AM (Source: MedicineNet Migraine General)
Source: MedicineNet Migraine General - June 5, 2018 Category: Neurology Source Type: news

9 Kinds of Bug Bites You Might Get This Summer — and What to Do About Them
This article originally appeared on Health.com (Source: TIME: Health)
Source: TIME: Health - June 4, 2018 Category: Consumer Health News Authors: Amanda Gardner / Health Tags: Uncategorized healthytime onetime public health Source Type: news

Menstrual Migraine: A Test plus Tips for Primary Care
How much do you know about menstrual migraine? Take our 8-question quiz to find out.   (Source: ConsultantLive)
Source: ConsultantLive - June 4, 2018 Category: Internal Medicine Authors: Susan Hutchinson, MD Tags: Headache and Migraine Source Type: news

Erenumab: First-in-Class, Approved for Migraine Prevention
Get all the need-to-know tidbits from the recent FDA-approval of erenumab, the first in its class drug for migraine prevention.   (Source: ConsultantLive)
Source: ConsultantLive - June 4, 2018 Category: Internal Medicine Authors: Veronica Hackenthal, MD Tags: Headache and Migraine Source Type: news

Erenumab: First-in-Class Approved for Migraine Prevention
Take a closer look at how erenumab, the first CGRP inhibitor to win FDA-approval for migraine prevention, earned that spot. (Source: ConsultantLive)
Source: ConsultantLive - June 4, 2018 Category: Internal Medicine Authors: Veronica Hackenthal, MD Tags: Headache and Migraine Source Type: news

Novartis receives positive CHMP opinion for Aimovig ® (erenumab) for the prevention of migraine
Novartis announced the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval for Aimovig® (erenumab) for the prevention of migraine in adults who have at least four migraine days per month. The World Health Organization (WHO) has listed migraine as one of the top ten causes of years lived with disability worldwide[1]. (Source: World Pharma News)
Source: World Pharma News - June 4, 2018 Category: Pharmaceuticals Tags: Featured Novartis Business and Industry Source Type: news

EU Panel Endorses Erenumab for Migraine Prevention EU Panel Endorses Erenumab for Migraine Prevention
An expert panel of the European Medicines Agency has recommended granting marketing authorization for erenumab, the first human monoclonal antibody for migraine prevention.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Alert Source Type: news

Novartis readies anti-sexism message for migraine drug
ZURICH (Reuters) - With women hardest hit by migraine headaches, Swiss drugmaker Novartis is gearing up its marketing message to counteract sexism that it worries might become a barrier to adoption of its new medicine Aimovig.   (Source: Reuters: Health)
Source: Reuters: Health - June 1, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Cefaly in Hot Pursuit of a Migraine Prevention Indication
Each year migraines are estimated to impact about 39 million people in the U.S. and about 1 billion worldwide. Chronic migraines are characterized by 15 or more headache days per month for at least three months.  Cefaly Technology has developed an electroceutical treatment platform that can tackle the neurological disease. However, the Belgium-based company is working on a new application for the Cefaly Prevent Device to focus on the chronic migraine population. “When we received [FDA] approval for the device in 2014, it was mainly based on the trials that were executed for acutely migraine sufferer – so p...
Source: MDDI - June 1, 2018 Category: Medical Devices Authors: Omar Ford Tags: Electronics Source Type: news

EMA committee recommends approval for migraine prevention drug
Novartis (NYSE:NVS) said today that a committee for the European Medicines Agency has recommended that the regulatory agency approve Aimovig, a self-administered drug designed to prevent migraines in adults who have at least four migraine days each month. The drug is the first of a new class of medicines, called CGRP inhibitors. It’s a monoclonal antibody that blocks the receptor for a protein that is linked to migraine pain, known as the calcitonin gene-related peptide. Just last month Aimovig, developed by Amgen (NSDQ:AMGN), won FDA approval in the U.S. Get the full story at our sister site...
Source: Mass Device - June 1, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Neurological Pharmaceuticals Regulatory/Compliance Wall Street Beat Amgen Novartis Source Type: news

Novartis wins key European panel's thumbs-up for migraine drug
(Reuters) - Novartis's new migraine drug Aimovig won a key recommendation from a key European panel on Friday, helping open the way for potential sales before the end of the year for a medicine the Swiss drugmaker is counting on to boost growth. (Source: Reuters: Health)
Source: Reuters: Health - June 1, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

CGRP inhibitors may be a good option for migraines
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - June 1, 2018 Category: Drugs & Pharmacology Source Type: news

Galcanezumab Injections Reduce Episodic Migraine Headache Days Galcanezumab Injections Reduce Episodic Migraine Headache Days
Injections of the calcitonin-gene-related peptide (CGRP) monoclonal antibody galcanezumab reduce monthly headache days in patients with episodic migraine, according to results from the EVOLVE-1 phase 3 study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 31, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Galcanezumab Beats Placebo for Episodic Migraine
THURSDAY, May 31, 2018 -- For patients with episodic migraine, galcanezumab is better than placebo for reducing migraine headache days, according to a study published online May 29 in JAMA Neurology. Virginia L. Stauffer, Pharm.D., from Eli Lilly... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 31, 2018 Category: Pharmaceuticals Source Type: news

Microvascular and large vein abnormalities in young patients after mild head trauma and associated fatigue: a brain SPECT evaluation and posture dependence modeling - Crider T, Eng D, Sarkar PR, Cordero J, Krusz JC, Sarkar SN.
OBJECTIVE: MRI and CT scans are usually normal in mild traumatic brain injury (mTBI) although 15-20% of such patients suffer for months from fatigue, headache, anxiety, sleep and other disorders. mTBI is suspected to be a cerebrovascular injury, similar to... (Source: SafetyLit)
Source: SafetyLit - May 30, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Another Drug to Prevent Migraines Shows Promise
Title: Another Drug to Prevent Migraines Shows PromiseCategory: Health NewsCreated: 5/29/2018 12:00:00 AMLast Editorial Review: 5/30/2018 12:00:00 AM (Source: MedicineNet Migraine General)
Source: MedicineNet Migraine General - May 30, 2018 Category: Neurology Source Type: news

How to get rid of a headache - 4p a day supplements could stop migraines
HOW to get rid of a headache: Headache pain can last for several hours, and may be very uncomfortable. Adding these cheap supplements to your diet could prevent a headache or migraine from coming back. (Source: Daily Express - Health)
Source: Daily Express - Health - May 29, 2018 Category: Consumer Health News Source Type: news

Another Drug to Prevent Migraines Shows Promise
Galcanezumab cut in half the number of days that most patients suffered from a migraine in a month, and did so without significant side effects,  researchers reported. (Source: WebMD Health)
Source: WebMD Health - May 29, 2018 Category: Consumer Health News Source Type: news

Galcanezumab Succeeds in Episodic Migraine Prevention (CME/CE)
(MedPage Today) -- But study recommends caution for patients with acute CV events or serious CV risk (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - May 29, 2018 Category: Psychiatry Source Type: news

Monthly News Roundup - May 2018
Aimovig Cleared as First-In-Class for Migraine Prevention Migraines are painful, debilitating headaches that can negatively affect a patient’s work and quality-of-life. This month the U.S. Food and Drug Administration (FDA) approved Amgen’s... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 29, 2018 Category: Pharmaceuticals Source Type: news

Trials Report Galcanezumab Shows Promise At Preventing Migraines
TUESDAY, May 29, 2018 -- Migraine sufferers could soon turn to a number of new medications to avoid their crippling headaches. Earlier this month, the U.S. Food and Drug Administration approved Aimovig (erenumab), the first migraine prevention drug... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 29, 2018 Category: General Medicine Source Type: news

Another Drug to Prevent Migraines Shows Promise
TUESDAY, May 29, 2018 -- Migraine sufferers could soon turn to a number of new medications to avoid their crippling headaches. Earlier this month, the U.S. Food and Drug Administration approved Aimovig (erenumab), the first migraine prevention drug... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 29, 2018 Category: General Medicine Source Type: news