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UIowa study examines altered gene expression in heart failure
(University of Iowa Health Care) Heart tissue from patients with heart failure exhibits increased levels of Cdk8 protein. Mimicking this increased Cdk8 expression in transgenic mouse hearts alters gene expression in a way that promotes heart failure. When University of Iowa researchers examined the mouse heart cells before a decrease in heart function was detectable, they found over 3,400 genes already expressed with a profile similar to that of human heart muscle cells with dilated cardiomyopathy and heart failure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 4, 2017 Category: International Medicine & Public Health Source Type: news

Dilated cardiomyopathy
(Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - April 28, 2017 Category: Consumer Health News Source Type: news

TTN Mutation May Not Rule Out Medical Therapy for Dilated Cardiomyopathy TTN Mutation May Not Rule Out Medical Therapy for Dilated Cardiomyopathy
In patients with dilated cardiomyopathy, loss-of-function mutations in the titin gene (TTN) do not preclude systolic function recovery following standard pharmacological therapy, according to Canadian researchers.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - April 26, 2017 Category: Radiology Tags: News Source Type: news

Meet the girl who has had four hearts – video
Born with a serious heart condition called dilated cardiomyopathy, Chloe Narbonne had five major operations – and four hearts – by the age of 12. She defied the odds to become the youngest person in Europe to receive an artificial heart thanks to groundbreaking surgery involving 30 NHS staff. Now Chloe, her mother and medical personnel tell her amazing story for the first timeContinue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 10, 2017 Category: Science Authors: Denis CampbellDavid LeveneKen MacfarlaneMichael Tait Tags: Health Doctors NHS Society UK news Medical research Science Source Type: news

Adding Defibrillator to CRT No Benefit in Dilated Cardiomyopathy
However, benefit is seen for addition of defibrillator therapy in patients with ischemic cardiomyopathy (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - April 3, 2017 Category: Respiratory Medicine Tags: Cardiology, Internal Medicine, Pulmonology, Journal, Source Type: news

Psoriasis and Cardiomyopathy: A Review of the Literature Psoriasis and Cardiomyopathy: A Review of the Literature
The incidence of dilated cardiomyopathy is 10 times higher in patients with psoriasis than in the general population. What might be the possible etiology of this association?Southern Medical Journal (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 30, 2017 Category: Allergy & Immunology Tags: Dermatology Journal Article Source Type: news

Medical News Today: Immune cell may turn heart inflammation into heart failure
New research examines the role of a type of white blood cells called eosinophils on heart inflammation, dilated cardiomyopathy, and heart failure in mice. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 16, 2017 Category: Consumer Health News Tags: Heart Disease Source Type: news

What is myocarditis? Pop legend George Michael suffered from condition, coroner reveals
MYOCARDITIS is an inflammation of the myocardium, which is a heart muscle. A coroner has revealed pop legend George Michael died from the condition - dilated cardiomyopathy with myocarditis and fatty liver. (Source: Daily Express - Health)
Source: Daily Express - Health - March 7, 2017 Category: Consumer Health News Source Type: news

MyoKardia begins dosing in Phase I trial of MYK-491 to treat DCM
US-based clinical stage biopharmaceutical firm MyoKardia has begun dosing in its Phase I single ascending dose clinical study of MYK-491 to treat dilated cardiomyopathy (DCM). (Source: Drug Development Technology)
Source: Drug Development Technology - February 6, 2017 Category: Pharmaceuticals Source Type: news

Happy birthday to my heart
In the foyer of the Geraghty house in Bedford, New Hampshire, 20 red heart-shaped balloons and a wall-to-wall banner welcome Erin Geraghty home from college. It’s not her birthday — she’s 21. It’s not her graduation — she’s a first-semester University of New Hampshire senior. And it’s not Valentine’s Day. It’s her 20th year with the same heart. Born with idiopathic dilated cardiomyopathy — a condition that causes the heart to pump blood inefficiently — Erin received a heart transplant at Boston Children’s Hospital when she was just 1 year old. Her sist...
Source: Thrive, Children's Hospital Boston - December 19, 2016 Category: Pediatrics Authors: Emily Williams Tags: Our Patients’ Stories Dr. Elizabeth Blume heart transplant Heart transplant program idiopathic dilated cardiomyopathy Pediatric Transplant Center (PTC) Source Type: news

Hearts of Healthy People With Gene Mutations May Be'Primed to Fail '
WEDNESDAY, Nov. 23, 2016 -- Certain gene mutations can increase the risk of heart failure in healthy people, researchers report. It had been believed that gene mutations in a protein called titin affect only people with dilated cardiomyopathy, one... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 23, 2016 Category: Journals (General) Source Type: news

Family Hears Their Late Daughter's Heart Beat Inside Organ Recipient
A Florida teen’s memory lives on through a strong heartbeat.  The family of 14-year-old Katelyn Zimmerman, who was killed by a drunk driver in March, recently met the person who received her heart, ABC 11 reported.  In the video below, Katelyn’s family listens to her heart beating inside Albert Jeffries IV. Albert, a 14-year-old from North Carolina with dilated cardiomyopathy, was flooded with emotion. “Thank you for the gift of being able to see more in life,” Albert, whose condition means his heart struggles to pump blood, tearfully read in a letter to Katelyn’...
Source: Healthy Living - The Huffington Post - July 28, 2016 Category: Consumer Health News Source Type: news

Identification of a gene signature associated with dilated cardiomyopathy
(Journal of Clinical Investigation) A study in this issue of JCI Insight identifies a gene signature that characterizes the transition from dilated cardiomyopathy to heart failure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 5, 2016 Category: Global & Universal Source Type: news

Potential heart disorder cause, treatment identified
A novel therapy tested scientists for treating a fatal heart disorder in dogs might ultimately help in diagnosing and treating heart disease in humans. The team also identified potential causes of inherited dilated cardiomyopathy (DCM) or "weak heart." (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 11, 2016 Category: Science Source Type: news

Peripartum and 'Idiopathic' Cardiomyopathies Share Gene VariantsPeripartum and 'Idiopathic' Cardiomyopathies Share Gene Variants
Pregnancy-related cardiomyopathy may share genetic underpinnings with idiopathic dilated cardiomyopathy, say researchers. "For the first time, we have an explanation for a subset of these women that is quite novel." Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - January 7, 2016 Category: Cardiology Tags: Cardiology News Source Type: news

Bone Marrow Cell Injection in Dilated CardiomyopathyBone Marrow Cell Injection in Dilated Cardiomyopathy
Might transplantation of autologous bone marrow mononuclear cells, delivered by intracoronary injection, improve heart function in patients with dilated cardiomyopathy? European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 8, 2015 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

ECG Challenge: Dilated CardiomyopathyECG Challenge: Dilated Cardiomyopathy
A 69-year-old man with a history of a dilated cardiomyopathy presents with several hours of palpitations and sudden onset of shortness of breath. Medscape Cardiology (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 27, 2015 Category: Cardiology Tags: Cardiology Case Challenge Source Type: news

Mayo Clinic Launches Eight Genetic Testing Panels for Cardiac Disorders
ROCHESTER, Minn. — Mayo Clinic’s launch of eight new next-generation sequencing (NGS) panels is intended to improve the lives of patients and families living with inherited cardiac conditions by aiding in the diagnosis and management of these complex disorders. These disorders include hypertrophic cardiomyopathy, dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, Noonan syndrome, Marfan syndrome, long [...] (Source: Mayo Clinic Rochester News)
Source: Mayo Clinic Rochester News - April 8, 2015 Category: Hospital Management Source Type: news

Cardiac Preload in Children With CV Dysfunction or Dilated CMCardiac Preload in Children With CV Dysfunction or Dilated CM
Find out about "normal" values for global end-diastolic volume index and more in pediatric patients with cardiovascular dysfunction and dilated cardiomyopathy. Pediatric Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 10, 2015 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news

Scientists find key gene mutations behind inherited heart disease
LONDON (Reuters) - Scientists have identified the crucial genetic mutations that cause a common heart condition called dilated cardiomyopathy (DCM), paving the way for more accurate diagnosis and screening of high-risk patients. (Source: Reuters: Health)
Source: Reuters: Health - January 14, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Heart transplant patient brings home the gold
  A rush of excitement swept over Alexia Clinton this past July as she walked into the 22,039 seat Houston Dynamo stadium, hearing her name along with the rest of Team New England called over the loudspeaker. The national youth athletic competition she had waited for all year was about to begin. In addition to winning gold for her softball throw, 10-year-old Alexia won silver in both swimming and long jump and bronze in cornhole. When you consider the fact that she had a heart transplant at the tender age of three, these accomplishments are all the more astonishing. Alexia was participating in the Transplant Games of ...
Source: Thrive, Children's Hospital Boston - January 2, 2015 Category: Pediatrics Authors: Erin Horan Tags: All posts heart transplant Source Type: news

Dilated Cardiomyopathy Therapeutic Pipeline Market Review H2 2014...
ReportsnReports.com adds “Dilated Cardiomyopathy Pipeline Review, H2 2014” to its store. The report provides an overview of the Dilated Cardiomyopathy therapeutic pipeline.(PRWeb December 31, 2014)Read the full story at http://www.prweb.com/releases/dilated-cardiomyopathy/pipeline-review-h2-2014/prweb12418227.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - January 1, 2015 Category: Pharmaceuticals Source Type: news

Thursday consumer health tips
Alzheimer's, dementia and MCI overlap but have different meanings Blood thinners: Can I still get blood clots? Dilated cardiomyopathy Stress management: Know your triggers Antidepressants and alcohol: What's the concern? (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 6, 2014 Category: Databases & Libraries Source Type: news

Thursday consumer health tips
Flu shots: Especially important if you have heart disease Barrett's esophagus Pain and depression: Is there a link? Dilated cardiomyopathy Inflammatory bowel disease (IBD) (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 16, 2014 Category: Databases & Libraries Source Type: news

Genetics Home Reference: dilated cardiomyopathy with ataxia syndrome
http://ghr.nlm.nih.gov/condition/dilated-cardiomyopathy-with-ataxia-syndrome (Source: NLM General Announcements)
Source: NLM General Announcements - August 5, 2014 Category: Databases & Libraries Source Type: news

Bionic heart patient relies on portable pump in handbag to transfer blood around body
Daniela Vargova, 30, from Chippenham, Wiltshire, was diagnosed with dilated cardiomyopathy following a cardiac arrest and now relies on the life-saving equipment. (Source: the Mail online | Health)
Source: the Mail online | Health - July 4, 2014 Category: Consumer Health News Source Type: news

News for the EORP Cardiomyopathy and Myocarditis Registry
On behalf of the Cardiomyopathy Executive Committee of the EURObservational Research Programme (EORP), we are pleased to announce the launch of the Long-Term Cardiomyopathies and Myocarditis Registry and invite you to contact us in order to participate in this exciting endeavour. The registry is open to adult and paediatric cardiology units. Data will be collected on the following disorders: hypertrophic cardiomyopathy; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; restrictive cardiomyopathy; and clinically suspected myocarditis. (Source: ESC News and Press)
Source: ESC News and Press - July 1, 2014 Category: Cardiology Source Type: news

Hope for normal heart function in children with fatal heart disease
After two decades of arduous research, an investigator has published a new study showing that many children with an often fatal type of heart disease can recover “normal size and function” of damaged sections of their hearts. The finding clearly demonstrates that nearly one-fourth of children treated for “idiopathic dilated cardiomyopathy,” or DCM, when these children with DCM become symptomatic by developing congestive heart failure) can be expected to fully recover normal size and function of left-ventricular (LV) heart muscle fibers within about two years of diagnosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 14, 2014 Category: Science Source Type: news

Mount Sinai Scientists Identify First Gene Linked to Heart Muscle...
Findings Show Several FDA-Approved Drugs May also be Effective in Patients Diagnosed with Dilated Cardiomyopathy(PRWeb April 28, 2014)Read the full story at http://www.prweb.com/releases/2014/04/prweb11798825.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - April 29, 2014 Category: Pharmaceuticals Source Type: news

Genetics Home Reference: familial dilated cardiomyopathy
http://ghr.nlm.nih.gov/condition/familial-dilated-cardiomyopathy (Source: NLM General Announcements)
Source: NLM General Announcements - December 17, 2013 Category: Databases & Libraries Source Type: news

Mother Ashton Hutcheson's shock at being told son has just 50/50 chance of survival
Ashton Hutcheson (pictured with his mother, Shanna), from Aberdeen, was eventually diagnosed with dilated cardiomyopathy after he developed stomach pain and sickness. (Source: the Mail online | Health)
Source: the Mail online | Health - December 9, 2013 Category: Consumer Health News Source Type: news

Genetic Test Helps Spot Familial CardiomyopathyGenetic Test Helps Spot Familial Cardiomyopathy
Using a new genetic testing strategy, researchers have identified new mutations that improve the ability to detect family members with inherited dilated cardiomyopathy. Heartwire (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 22, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news

Sequencing of Hypertrophic and Dilated Cardiomyopathy GenesSequencing of Hypertrophic and Dilated Cardiomyopathy Genes
Is next generation sequencing for cardiomyopathy genes ready for implementation in a diagnostic setting? Journal of Medical Genetics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 19, 2013 Category: Consumer Health News Tags: Business of Medicine Journal Article Source Type: news

Sports and Life Lessons Collide at World Transplant Games
Brock and Connor recently returned from the 2013 World Transplant Games in South Africa By Brock Marvin  “Tough times never last, but tough people do.” This is what I told myself every single day that I battled severe dilated cardiomyopathy. And the phrase stayed with me for the months after my eventual heart transplant at Boston Children’s Hospital Heart Transplant Program in 2010. I always had plenty of faith that there were happier, healthier days ahead; I just needed to work a little harder than most teenagers to get there. But I wasn’t alone in the battle. Months after...
Source: Thrive, Children's Hospital Boston - September 18, 2013 Category: Pediatrics Authors: Guest Blogger Tags: All posts Our patients’ stories Sports & exercise Teen health congenital heart defect Elizabeth Blume heart transplant Pediatric Transplant Center (PTC) Source Type: news

From the surgical suite to the winner’s podium: brothers treated at Boston Children’s compete in the World Transplant Games
Though they’re two years apart, brothers Brock and Connor Marvin have a lot in common. They’re both affable, active young men who love watching and playing sports. Brock, the eldest, is a goal keeper for Oglethorpe University’s soccer team, while Connor holds places on his high school’s varsity soccer, basketball and golf teams. They were also both born with a genetic heart condition so severe it would require them to receive heart transplants within a year and a half of each other. A sudden shock On an April evening in 2008, Brock and Connor were killing time the way they normally did by tossing a ...
Source: Thrive, Children's Hospital Boston - July 30, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Our patients’ stories Sports & exercise Teen health congential heart defect Elizabeth Blume heart transplant Pediatric Transplant Center (PTC) Source Type: news

Stem Cells, Duchenne Muscular Dystrophy (DCM) & Cardiomyopathies
Conclusion: ADMs delay or prevent development of DCM in dystrophin-deficient heart, but timing of stem cell transplantation may be critical for achieving benefit with cell therapy in DMDcardiac muscle.Stem Cell Research Reagents. (Source: Neuromics)
Source: Neuromics - January 21, 2013 Category: Neuroscience Tags: Cardiomyopathy DCM ADMs Duchenne Muscular Dystrophy nestin antibodies Aorta-derived mesoangioblasts nestin antibody Stem cell markers cardiomyocytes Source Type: news

Cardio Notes: Two Meds Key in PAD Surgery
(MedPage Today) -- Patients scheduled for a peripheral artery intervention do much better if they are already on statins and aspirin. Also this week, predictors of new-onset dilated cardiomyopathy. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 14, 2013 Category: Primary Care Source Type: news

Transplantation of Engineered Heart Tissue in Dilated CardiomyopathyTransplantation of Engineered Heart Tissue in Dilated Cardiomyopathy
Is a new bridge to heart transplantation on the horizon? European Journal of Heart Failure (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 11, 2013 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news