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Despite 'bad press,' new blood thinners aren't linked to greater bleeding risk: Study
New anti-clotting drugs -- like Xarelto, Pradaxa and Eliquis -- aren't linked with a higher risk of bleeding than the older drug warfarin, a new study finds (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 18, 2017 Category: Consumer Health News Source Type: news

Newer Blood Thinners May Not Bring Higher Bleeding Risk
WEDNESDAY, Oct. 18, 2017 -- New anti-clotting drugs -- like Xarelto, Pradaxa and Eliquis -- aren't linked with a higher risk of bleeding than the older drug warfarin, a new study finds. Many patients who suffer from blood clots in their legs --... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 18, 2017 Category: General Medicine Source Type: news

Thrombolysis for Ischemic Stroke After Reversal of Dabigatran Thrombolysis for Ischemic Stroke After Reversal of Dabigatran
Is idarucizumab administration safe and effective in patients with AF treated with dabigatran who develop acute ischemic stroke requiring thrombolysis?Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 9, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Data Bolster Dual Antithrombotic Therapy in AF PCI Patients Data Bolster Dual Antithrombotic Therapy in AF PCI Patients
A new study supports forgoing traditional triple antithrombotic therapy with aspirin for dual therapy with dabigatran and a P2Y12 inhibitor in patients with atrial fibrillation who've undergone PCI.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 20, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

When two is better than three: Dual antithrombotic therapy cuts bleeding risk
(Brigham and Women's Hospital) Clinical trial finds that dabigatran dual therapy after stenting reduced bleeding risk for patients with atrial fibrillation compared with standard triple therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 27, 2017 Category: International Medicine & Public Health Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include antibody depletion for kidney transplantation, a way to reverse dabigatran, the costs of board certification, and opioid use in the U.S. population (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - August 5, 2017 Category: Psychiatry Source Type: news

FDA Drug Safety Communication: Special storage and handling requirements must be followed for Pradaxa (dabigatran etexilate mesylate) capsules
[03-29-2011] The U.S. Food and Drug Administration (FDA) is alerting the public to important storage and handling requirements for Pradaxa (dabigatran etexilate mesylate) capsules. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 4, 2017 Category: Drugs & Pharmacology Source Type: news

Thomas Jefferson Researcher Publishes Study Showing Treatment Rapidly...
A new treatment rapidly removes the oral blood thinner dabigatran (PRADAXA®) from circulation within minutes, allowing life-saving clots to form normally(PRWeb July 18, 2017)Read the full story at http://www.prweb.com/releases/2017/07/prweb14497643.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - July 18, 2017 Category: Pharmaceuticals Source Type: news

Idarucizumab Shows Reliable Reversal of Dabigatran
Effective for dabigatran reversal among patients with uncontrolled bleeding, undergoing urgent surgery (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - July 13, 2017 Category: Respiratory Medicine Tags: Cardiology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Oncology, Orthopedics, Pharmacy, Pulmonology, Surgery, Anesthesiology & Pain, Conference News, Source Type: news

Rapid Reversal of Dabigatran Anticoagulation With Idarucizumab Rapid Reversal of Dabigatran Anticoagulation With Idarucizumab
Idarucizumab rapidly and consistently reverses the anticoagulant effect of oral agent dabigatran, aiding patients with bleeds and allowing emergency invasive procedures, the RE-VERSE AD study shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 13, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Idarucizumab Confirmed to Work as NOAC Reversal Agent (CME/CE)
(MedPage Today) -- Full cohort findings detail rapid effects independent of circulating dabigatran (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - July 11, 2017 Category: Cardiology Source Type: news

Treatment rapidly reverses the effect of blood thinner dabigatran
At least 28 million prescriptions for blood thinners are filled by pharmacists yearly for the irregular heartbeat of atrial fibrillation, deep vein thrombosis, and other indications, according to the Department of Health and Human Services. However, on rare occasions, anticoagulants can present risks of accidental bleeding and hemorrhage or can delay emergency surgery. A newly completed phase III clinical study demonstrates the safety and efficacy of idarucizumab, a novel therapy that acts as an antidote to the blood thinner dabigatran. (Source: World Pharma News)
Source: World Pharma News - July 11, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Treatment rapidly reverses the effect of blood thinner dabigatran
(Thomas Jefferson University) A new treatment rapidly removes the oral blood thinner dabigatran (PRADAXA ® ) from circulation within minutes, allowing life-saving clots to form normally. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 11, 2017 Category: International Medicine & Public Health Source Type: news

Safety and Efficacy of Dabigatran Reversal Agent Confirmed (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Idarucizumab — a humanized monoclonal antibody approved to reverse the anticoagulant effects of dabigatran — acts quickly and safely in emergency situations, according to final … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 11, 2017 Category: Primary Care Source Type: news

Dabigatran reduces resource use versus warfarin but not costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - June 30, 2017 Category: Drugs & Pharmacology Source Type: news

Pradaxa (Dabigatran Etexilate Mesylate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 5, 2017 Category: Drugs & Pharmacology Source Type: news

All About Dabigatran Reversal in the ED
(MedPage Today) -- Agent now available for reversing new oral anticoagulant in bleeding patients (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - April 15, 2017 Category: American Health Source Type: news

Mar 31 Cardiology News Mar 31 Cardiology News
High-sensitivity troponin testing, dabigatran during AF ablation, valve-in-valve TAVR, Impella, and the ARNI valsartan/sacubitril's effect on HbA1c are discussed in this week's podcast.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 31, 2017 Category: Cardiology Tags: Cardiology News Source Type: news

Fewer Bleeds on Uninterrupted Dabigatran vs Warfarin in AF Ablation Fewer Bleeds on Uninterrupted Dabigatran vs Warfarin in AF Ablation
"Now we have high-quality data showing that if you perform this procedure on uninterrupted dabigatran, the risk of stroke is extremely low," said a researcher about the randomized RE-CIRCUIT trial.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 28, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Afib Patients Taking Warfarin May Have Higher Fracture Risk (CME/CE)
(MedPage Today) -- Difference vs dabigatran only in individuals with previous falls or fractures (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 21, 2017 Category: Cardiology Source Type: news

Pradaxa Beats Warfarin After Heart Rhythm Procedure: Study
Patients undergoing surgery to treat an irregular heartbeat are less likely to suffer problematic bleeding when given Pradaxa instead of warfarin, a study finds. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 20, 2017 Category: Consumer Health News Source Type: news

Pradaxa Beats Warfarin After AFib Procedure
Fewer bleeding problems reported among 'ablation' patients who took the newer blood thinner (Source: WebMD Health)
Source: WebMD Health - March 20, 2017 Category: Consumer Health News Source Type: news

Pradaxa Beats Warfarin After Heart Rhythm Procedure
Fewer bleeding problems reported among 'ablation' patients who took the newer blood thinner Source: HealthDay Related MedlinePlus Pages: Atrial Fibrillation, Blood Thinners (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 20, 2017 Category: Consumer Health News Source Type: news

Pradaxa Beats Warfarin After Heart Rhythm Procedure: Study
MONDAY, March 20, 2017 -- Patients undergoing a surgical procedure to treat an irregular heartbeat are less likely to suffer problematic bleeding when given the blood thinner Pradaxa rather than warfarin, a new study finds. The two blood thinners... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 20, 2017 Category: Journals (General) Source Type: news

Pradaxa Beats Warfarin After Heart Rhythm Procedure: Study
Title: Pradaxa Beats Warfarin After Heart Rhythm Procedure: StudyCategory: Health NewsCreated: 3/20/2017 12:00:00 AMLast Editorial Review: 3/20/2017 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - March 20, 2017 Category: Cardiology Source Type: news

ACC: NOAC Safer for Use in Afib Ablation
(MedPage Today) -- For uninterrupted anticoagulation, dabigatran lessened bleeding events (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 19, 2017 Category: Cardiology Source Type: news

Prescription drugs declared "one of the most significant perils to human health" by British medical journal
(Natural News) Prescription drug therapy has been a major contributor to the soaring rates of serious, disabling or fatal injuries, according to a 2011 study published in the British Journal of Medicine. Data from the Institute for Safe Medication Practices showed that anticoagulants dabigatran and warfarin were the most frequently identified medications that were reported to... (Source: NaturalNews.com)
Source: NaturalNews.com - March 15, 2017 Category: Consumer Health News Source Type: news

Dec 2 Cardiology News Dec 2 Cardiology News
Subclinical AF, chest-pain evaluation, proton-pump inhibitors and stroke risk, dabigatran-statin interactions, and Watchman are topics discussed by Dr John Mandrola in this week's podcast.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 2, 2016 Category: Cardiology Tags: Cardiology News Source Type: news

Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode: Study
Title: Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode: StudyCategory: Health NewsCreated: 12/1/2016 12:00:00 AMLast Editorial Review: 12/2/2016 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - December 2, 2016 Category: Cardiology Source Type: news

Pradaxa May Beat Warfarin After Bleeding Episode
Research also shows that resuming any anticoagulant is still safer than stopping the drugs in these cases (Source: WebMD Health)
Source: WebMD Health - December 1, 2016 Category: Consumer Health News Source Type: news

Statins and Dabigatran: New Interaction?
A signal for increased risk of hemorrhage when the NOAC is coadministered with 2 statins comes as a surprise to some. (Source: ConsultantLive)
Source: ConsultantLive - December 1, 2016 Category: Internal Medicine Authors: Payal Kohli, MD Tags: Atrial Fibrillation Cardiovascular Diseases Cerebrovascular Diseases Source Type: news

Statins and Dabigatran: Possible Interaction?
A signal for increased risk of hemorrhage when the NOAC is coadministered with 2 statins comes as a surprise to some. (Source: ConsultantLive)
Source: ConsultantLive - December 1, 2016 Category: Internal Medicine Authors: Payal Kohli, MD Tags: Atrial Fibrillation Cardiovascular Diseases Cerebrovascular Diseases Source Type: news

Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode
Research also shows that resuming any anticoagulant is still safer than stopping the drugs in these casesSource: HealthDay Related MedlinePlus Pages: Bleeding, Blood Thinners, Stroke (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - December 1, 2016 Category: Consumer Health News Source Type: news

High Adherence Rates with Pradaxa in NVAF Patients
(Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - December 1, 2016 Category: Research Source Type: news

Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode: Study
THURSDAY, Dec. 1, 2016 -- Use of a blood thinner is routine for many heart patients, but these drugs come with a risk of episodes of excess bleeding. What, if any, anticoagulant (blood thinner) should these patients take after such episodes... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 1, 2016 Category: Journals (General) Source Type: news

Dabigatran superior to warfarin when anticoagulation is resumed after bleeding
(University of Pittsburgh Schools of the Health Sciences) In the first analysis of how to treat patients on anticoagulants who suffer a major bleeding event, a clinical practice that routinely gives doctors pause, while also evaluating a new drug, University of Pittsburgh researchers aim to provide much-needed guidance to clinicians trying to balance the risks of stroke versus bleeding when determining the best treatment. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - December 1, 2016 Category: Global & Universal Source Type: news

Dabigatran Bleed Risk With Two Statins in Study Raises Eyebrows Dabigatran Bleed Risk With Two Statins in Study Raises Eyebrows
"Both statins and anticoagulation for strokes save lives, and people should not jump to conclusions and stop their drugs" based on a single, flawed publication, an expert says.Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 25, 2016 Category: Cardiology Tags: Cardiology News Source Type: news

Irregular heartbeat drug combo may raise bleeding risk
HealthDay News A Canadian study suggests combining one blood thinner, Pradaxa, with certain statin medications may raise the odds for bleeding in atrial fibrillation patients. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 21, 2016 Category: Consumer Health News Source Type: news

Drug Combo for AFib Might Raise Bleeding Risk
Study found heightened odds when blood thinner Pradaxa was taken with one of two statin drugs (Source: WebMD Health)
Source: WebMD Health - November 21, 2016 Category: Consumer Health News Source Type: news

Drug Combo for Irregular Heartbeat Might Raise Bleeding Risk
Study found heightened odds when blood thinner Pradaxa was taken with one of two statin drugs Source: HealthDay Related MedlinePlus Pages: Atrial Fibrillation, Blood Thinners, Statins (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 21, 2016 Category: Consumer Health News Source Type: news

Drug Combo for Irregular Heartbeat Might Raise Bleeding Risk
MONDAY, Nov. 21, 2016 -- Because the irregular heartbeat known as atrial fibrillation can trigger stroke-inducing clots, many patients are prescribed a blood thinner. But a new Canadian study suggests that combining one blood thinner, Pradaxa, with... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 21, 2016 Category: Journals (General) Source Type: news

Dabigatran Antidote Fast, Effective in RE-VERSE AD: Now What? Dabigatran Antidote Fast, Effective in RE-VERSE AD: Now What?
It works, seems safe in patients with serious bleeds or needing urgent surgery, but its likely clinical impact is unclear. Some wonder, will bleeds go up as idarucizumab promotes more dabigatran use?Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 17, 2016 Category: Cardiology Tags: Cardiology News Source Type: news

Enrollment completed for RE-DUAL PCI ™ study of 2,700 atrial fibrillation patients
(WHITECOAT STRATEGIES, LLC) The Baim Institute announces that patient enrollment into the international Phase IIIb RE-DUAL PCI ™ study is complete. The study evaluates the safety and efficacy of dabigatran etexilate (marketed as Pradaxa ® ) in atrial fibrillation patients undergoing a percutaneous coronary intervention with stent placement. This is the first time that two dosages of a non-vitamin K antagonist oral anticoagulant already approved for stroke prevention in AF are evaluated in a dual versus triple antithrombotic regimen after PCI. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 14, 2016 Category: Global & Universal Source Type: news

rt-PA After Antagonizing Dabigatran by Idarucizumab rt-PA After Antagonizing Dabigatran by Idarucizumab
This case demonstrates the safe and successful treatment of ischemic stroke with rt-PA in a patient on dabigatran, following reversal of dabigatran with idarucizumab.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 8, 2016 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Researchers Publish Largest Observational Study To-Date Comparing Novel Oral Anticoagulants (NOACs) Pradaxa ® (dabigatran etexilate mesylate) and Rivaroxaban
(Source: Boehringer Ingelheim Press Releases)
Source: Boehringer Ingelheim Press Releases - October 5, 2016 Category: Research Source Type: news

CardioBrief: More Bleeds With Rivaroxaban in Real-World Comparison
(MedPage Today) -- More intracranial, other serious bleeds than with dabigatran in Medicare data (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 5, 2016 Category: Cardiology Source Type: news

Fewer Major Bleeds on Dabigatran vs Rivaroxaban for AF Fewer Major Bleeds on Dabigatran vs Rivaroxaban for AF
In elderly patients with nonvalvular atrial fibrillation (AF), dabigatran and rivaroxaban provide comparable protection against thromboembolic stroke but dabigatran is safer, according to a new analysis.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 4, 2016 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Some Increased Bleeding Risk Seen With Blood Thinner Xarelto Vs. Pradaxa
Title: Some Increased Bleeding Risk Seen With Blood Thinner Xarelto Vs. PradaxaCategory: Health NewsCreated: 10/3/2016 12:00:00 AMLast Editorial Review: 10/4/2016 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - October 4, 2016 Category: Cardiology Source Type: news

Some Increased Bleeding Risk Seen With Blood Thinner Xarelto Vs. Pradaxa
But study wasn't definitive, and heart experts say both newer drugs are better than warfarin (Source: WebMD Health)
Source: WebMD Health - October 3, 2016 Category: Consumer Health News Source Type: news

Some Bleeding Risk Seen With Xarelto Vs. Pradaxa
But study wasn't definitive, and heart experts say both newer drugs are better than warfarin (Source: WebMD Health)
Source: WebMD Health - October 3, 2016 Category: Consumer Health News Source Type: news