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Newer Blood Thinners Don't Raise Bleeding Risk
Risk is similar to warfarin, study reports (Source: WebMD Health)
Source: WebMD Health - October 18, 2017 Category: Consumer Health News Source Type: news

Despite 'bad press,' new blood thinners aren't linked to greater bleeding risk: Study
New anti-clotting drugs -- like Xarelto, Pradaxa and Eliquis -- aren't linked with a higher risk of bleeding than the older drug warfarin, a new study finds (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 18, 2017 Category: Consumer Health News Source Type: news

Newer Blood Thinners May Not Bring Higher Bleeding Risk
Risk is similar to warfarin, study reports Source: HealthDay Related MedlinePlus Pages: Atrial Fibrillation, Blood Thinners, Deep Vein Thrombosis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 18, 2017 Category: Consumer Health News Source Type: news

Newer Blood Thinners May Not Bring Higher Bleeding Risk
WEDNESDAY, Oct. 18, 2017 -- New anti-clotting drugs -- like Xarelto, Pradaxa and Eliquis -- aren't linked with a higher risk of bleeding than the older drug warfarin, a new study finds. Many patients who suffer from blood clots in their legs --... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 18, 2017 Category: General Medicine Source Type: news

In VTE, Bleeding Risk No Higher with Direct Oral Anticoagulants Than Warfarin (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Direct oral anticoagulants do not pose higher risk for major bleeding than warfarin in patients with venous thromboembolism (VTE), according … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 18, 2017 Category: Primary Care Source Type: news

Direct oral anticoagulants as safe as warfarin after VTE
Major bleeding or death no more likely with DOACs than with warfarin in first 90 days ’ treatment Related items fromOnMedica Antidotes for new oral anticoagulants – will they make a difference? Self-managing anticoagulants may cut risks after surgery Extending anticoagulation duration cuts risk of VTE recurrence NOACs instead of warfarin (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 18, 2017 Category: UK Health Source Type: news

CardioBrief: NOACs Not Linked To Excess Bleeding in Real World
(MedPage Today) -- Observational study compares new anticoagulants to warfarin in VTE (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - October 17, 2017 Category: Surgery Source Type: news

You won ’t believe what happened this morning
When I got to the office this morning, several of my employees were in a state of near-panic… I couldn’t imagine what might have happened… and I was alarmed. Turns out, the coffee maker was on the fritz. Coffee is the “drug” of choice for many of the people on my staff. And they’re not alone… An astounding 80% of Americans use the caffeine in coffee to boost their energy. The buzz helps them wake up every morning and gets their day going. And older adults drink coffee more than anyone else. In fact, in a survey by the National Coffee Association, 20% of people over 64 said they ...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Genetic testing improves blood thinner dosing
Researchers found that genetics-based dosing for the blood thinner warfarin reduces the risk of major side effects in older patients starting the medication. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 2, 2017 Category: Consumer Health News Source Type: news

Replacing Warfarin With a Novel Oral Anticoagulant Replacing Warfarin With a Novel Oral Anticoagulant
A good percentage of patients with atrial fibrillation may be ineligible for warfarin due to increased risk of major bleeding or recurrent systemic thromboembolism. Are DOACs a viable alternative?Journal of Cardiovascular Electrophysiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 2, 2017 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include aspirin discontinuation risks, HIV in those 50 and older, big data and chronic lung disease, and genetic testing and warfarin use (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 30, 2017 Category: Cardiology Source Type: news

Genetic testing may help determine appropriate dose of warfarin among patients undergoing hip or knee arthroplasty
Findings from a study published online in The Journal of the American Medical Association suggest that, compared to clinically guided dosing, genotype-guided warfarin dosing may reduce the risk of adverse events for joint arthroplasty patients.  (Source: Orthogate - Latest News)
Source: Orthogate - Latest News - September 30, 2017 Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

Drug safety update: Miconazole (Daktarin): over-the-counter oral gel contraindicated in patients taking warfarin
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update with advice that patients taking warfarin should not use over-the-counter miconazole oral gel (Daktarin). (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 29, 2017 Category: Drugs & Pharmacology Source Type: news

Genotype-Guided Warfarin Dosing Reduces Adverse Events After Hip, Knee Arthroplasty (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Genotype-guided dosing of warfarin in older adults undergoing elective hip or knee arthroplasty helps prevent adverse events, according to a JAMA study.Roughly … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 27, 2017 Category: Primary Care Source Type: news

Genetic Testing May Help Make Blood Thinner Safer
Dosing adjustments for warfarin can be more precise, researchers say Source: HealthDay Related MedlinePlus Pages: Blood Thinners, Genetic Testing (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - September 26, 2017 Category: Consumer Health News Source Type: news

Genetic Testing May Help Make Warfarin Safer
TUESDAY, Sept. 26, 2017 -- Genetic testing can improve the safety of the blood thinner warfarin, a new study reports. Warfarin (Coumadin, Jantoven) is often prescribed to prevent life-threatening blood clots in high-risk patients. However, a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 26, 2017 Category: General Medicine Source Type: news

Genotyping Lowers Warfarin Risk in Hip or Knee Replacement Genotyping Lowers Warfarin Risk in Hip or Knee Replacement
Considering variants of three genes that affect response to warfarin improved the safety of using the drug.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 26, 2017 Category: Consumer Health News Tags: Internal Medicine News Source Type: news

CardioBrief: Genotyping Reduces Adverse Eventswith Warfarin
(MedPage Today) -- But still unclear whether benefit justifies the cost (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 26, 2017 Category: Cardiology Source Type: news

CardioBrief: Genotyping Reduces Adverse Events with Warfarin
(MedPage Today) -- But still unclear whether benefit justifies the cost (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - September 26, 2017 Category: Geriatrics Source Type: news

Genetic testing can help determine safest dose of blood thinner
(Hospital for Special Surgery) A new study finds that genetic testing can help determine the safest dose of the blood thinner warfarin, with fewer side effects, in patients having joint replacement surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 26, 2017 Category: International Medicine & Public Health Source Type: news

More Post-endoscopy GI Bleeding With Warfarin Than Direct Oral Anticoagulants More Post-endoscopy GI Bleeding With Warfarin Than Direct Oral Anticoagulants
Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - September 21, 2017 Category: Surgery Tags: Gastroenterology News Source Type: news

Early Anticoagulation Strategies Comparable After Afib-Related Stroke (CME/CE)
(MedPage Today) -- NOAC, warfarin show similar safety and efficacy after mild acute ischemic stroke (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 11, 2017 Category: Cardiology Source Type: news

How Moldy Hay And Sick Cows Led To A Lifesaving Drug
The blood thinner warfarin, which prevents blood clots, owes its existence to some cows who got very sick after eating the wrong hay. That and a chemist who spent years trying to figure out why.(Image credit: Avi Ofer) (Source: NPR Health and Science)
Source: NPR Health and Science - August 29, 2017 Category: Consumer Health News Authors: Joe Palca Source Type: news

Apixaban lowers stroke risk in AF patients undergoing cardioversion (EMANATE)
(European Society of Cardiology) Apixaban lowers the risk of stroke compared to warfarin in anticoagulation-na ï ve patients with atrial fibrillation scheduled for elective cardioversion, according to late-breaking results from the EMANATE trial presented today in a Hot Line LBCT Session at ESC Congress. Rates of bleeding were similar between the two groups. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 28, 2017 Category: International Medicine & Public Health Source Type: news

Study: Aspirin Safe for HF Patients (CME/CE)
(MedPage Today) -- Post-hoc WARCEF trial analysis shows no significant risks vs warfarin (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - August 1, 2017 Category: Cardiology Source Type: news

New Research Supports Safety of Aspirin in Heart Failure
Large trial comparing it to warfarin finds aspirin not tied to more hospitalizations or deaths (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - August 1, 2017 Category: Respiratory Medicine Tags: Cardiology, Endocrinology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Nursing, Pharmacy, Pulmonology, Journal, Source Type: news

Study: Aspirin Safe for Heart Failure Patients
Large trial comparing it to warfarin finds aspirin not tied to more hospitalizations or deaths (Source: WebMD Health)
Source: WebMD Health - July 31, 2017 Category: Consumer Health News Source Type: news

Aspirin Safe for Heart Failure Patients, Study Finds
Large trial comparing it to warfarin finds aspirin not tied to more hospitalizations or deaths Source: HealthDay Related MedlinePlus Pages: Blood Thinners, Heart Failure (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 31, 2017 Category: Consumer Health News Source Type: news

How Long Does Coumadin (warfarin) Stay in Your System?
Title: How Long Does Coumadin (warfarin) Stay in Your System?Category: Doctor's& Expert's views on SymptomsCreated: 7/11/2017 12:00:00 AMLast Editorial Review: 7/11/2017 12:00:00 AM (Source: MedicineNet High Blood Pressure General)
Source: MedicineNet High Blood Pressure General - July 11, 2017 Category: Cardiology Source Type: news

Dabigatran reduces resource use versus warfarin but not costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - June 30, 2017 Category: Drugs & Pharmacology Source Type: news

Registry Data Support NOACs for Single-Risk-Factor AF Registry Data Support NOACs for Single-Risk-Factor AF
Ischemic strokes rates were similar between atrial fibrillation patients treated with novel oral anticoagulants and warfarin, but imbalances in the study groups have raised questions.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 23, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Jantoven (Warfarin Sodium Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 16, 2017 Category: Drugs & Pharmacology Source Type: news

Warfarin, Atrial Fibrillation, and Kidney Function Warfarin, Atrial Fibrillation, and Kidney Function
What do we know about the safety and efficacy of warfarin use among older adults with atrial fibrillation and chronic kidney disease?American Journal of Kidney Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 15, 2017 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Risk of aspirin-related bleeding is higher in the over-75s
Conclusion This valuable cohort study helps to quantify the extent of bleeding risk in people taking aspirin for secondary prevention of cardiovascular disease. Aspirin is well known to carry bleeding risk – particularly in older adults – but this study suggests the risk may be higher than previously thought. The researchers say that for adults under the age of 75, the annual bleeding risk at around 1% is similar to that suggested by previous trials, as is the ratio of bleeds to the number of cardiovascular events. However, this risk increases for older adults, especially for major bleeds of the stomach and upp...
Source: NHS News Feed - June 14, 2017 Category: Consumer Health News Tags: Medication Older people Source Type: news

Rivaroxaban vs. Warfarin in a Patient With AF and LAA Thrombus Rivaroxaban vs. Warfarin in a Patient With AF and LAA Thrombus
This case highlights the possibility of using rivaroxaban as a safe and effective alternative to warfarin in complex cases involving certain thrombophilic conditions.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 2, 2017 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Warfarin OK in Expectant Moms with Mechanical Heart Valve
(MedPage Today) -- VKAs generally safer than heparin, according to meta-analysis (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - May 30, 2017 Category: Geriatrics Source Type: news

Delayed Anticoagulation Raises Dementia Risk in AF Patients Delayed Anticoagulation Raises Dementia Risk in AF Patients
"Unfortunately, the majority of patients who are started on warfarin are started more than 30 days after their initial diagnosis of AF," the lead author said.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 13, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Boston Scientific touts 1-year stroke reduction results in Watchman non-valvular AF trial
Boston Scientific (NYSE:BSX) today released 1-year results from the Ewolution registry study of its Watchman left atrial appendage closure device, touting a high implant success rate and stroke reduction in patients with non-valvular atrial fibrillation patients. Data was presented today at the Heart Rhythm Society’s 39th Annual Scientific Sessions in Chicago. “We are pleased to see that these ‘real-world’ results reinforce the positive outcomes observed in our clinical trial program, despite the registry patients being older and sicker than those enrolled in our previous trials,” rh...
Source: Mass Device - May 12, 2017 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Clinical Trials Boston Scientific Source Type: news

Non-major Bleeding in AF Patients on Apixaban vs. Warfarin Non-major Bleeding in AF Patients on Apixaban vs. Warfarin
This study suggests that even non-major bleeding events in patients on oral anticoagulation therapy for AF can have serious outcomes. Is apixaban safer than warfarin in this regard?Heart (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - April 28, 2017 Category: Surgery Tags: Cardiology Journal Article Source Type: news

Study Supports Rivaroxaban as Safe Alternative to Warfarin in VTE (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM A new study adds to evidence that rivaroxaban is a safe and effective alternative to warfarin in patients with unprovoked venous … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - April 13, 2017 Category: Primary Care Source Type: news

Apr 7 Cardiology News Apr 7 Cardiology News
Cost effects of risk-factor management in AF, apixaban costs vs warfarin, bioresorbable-scaffold woes, exercise as heart-failure therapy, and surgical left atrial appendage closure are discussed.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 7, 2017 Category: Cardiology Tags: Cardiology News Source Type: news

Apixaban Cost-effective vs Warfarin in AF: ARISTOTLE Apixaban Cost-effective vs Warfarin in AF: ARISTOTLE
A lifetime on the newer agent was cost-effective within US"reasonable norms" but didn't cut overall costs much by improving outcomes, mostly because apixaban itself is far costlier than warfarin. (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 5, 2017 Category: Cardiology Tags: Cardiology News Source Type: news

Use of Warfarin in Veterans With AF After Dementia Diagnosis Use of Warfarin in Veterans With AF After Dementia Diagnosis
Should older adults with AF who have been taking warfarin for stroke prevention continue therapy after being diagnosed with dementia?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 31, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

NOAC'Reasonably' Cost-Effective in Afib (CME/CE)
(MedPage Today) -- Apixaban analysis shows about $54k per QALY vs warfarin (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 29, 2017 Category: Primary Care Source Type: news

No Increased Risks for DOAC Use Versus Warfarin in VTE
Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - March 28, 2017 Category: Respiratory Medicine Tags: Cardiology, Family Medicine, Geriatrics, Internal Medicine, Critical Care, Emergency Medicine, Neurology, Nursing, Pathology, Pharmacy, Pulmonology, Journal, Source Type: news

Fewer Bleeds on Uninterrupted Dabigatran vs Warfarin in AF Ablation Fewer Bleeds on Uninterrupted Dabigatran vs Warfarin in AF Ablation
"Now we have high-quality data showing that if you perform this procedure on uninterrupted dabigatran, the risk of stroke is extremely low," said a researcher about the randomized RE-CIRCUIT trial.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 28, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Your NEJM Group Today: NEJM Knowledge+ Pediatrics / GI Bleeding with Direct Oral Anticoagulants vs. Warfarin / New Hampshire Family Medicine Opportunity (FREE)
By the Editors Here's today's offering from NEJM Group:NEJM Knowledge+ Pediatrics: We're pleased to announce the launch of NEJM Knowledge+ Pediatrics Board Review. This program … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 28, 2017 Category: Primary Care Source Type: news

Assessing Stroke Risk in Adult Congenital Heart Disease Assessing Stroke Risk in Adult Congenital Heart Disease
Drs Lyle, Ammash, and McLeod discuss risk stratification for stroke in adults with complex congenital heart disease and how to choose between warfarin or the direct oral anticoagulants in the absence of data.Mayo Clinic (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 27, 2017 Category: Consumer Health News Tags: Cardiology Commentary Source Type: news

Low-dose Apixaban May Be Safe Anti-stroke Option for Dialysis Patients Low-dose Apixaban May Be Safe Anti-stroke Option for Dialysis Patients
Low-dose apixaban achieves blood levels that appear to be safe and might be a “ reasonable alternative ” to warfarin for preventing stroke in patients with atrial fibrillation who are on hemodialysis, new research suggests.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - March 24, 2017 Category: Intensive Care Tags: Neurology & Neurosurgery News Source Type: news

Dosing Crucial for Digoxin, Warfarin Safety
(MedPage Today) -- Digoxin unsafe at high levels regardless of heart failure (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 21, 2017 Category: Cardiology Source Type: news