Apixaban is a safe alternative to warfarin during catheter ablation of atrial fibrillation
(European Society of Cardiology) Apixaban and warfarin are equally safe during catheter ablation of atrial fibrillation, according to results of the AXAFA-AFNET 5 trial presented today in a late-breaking trial session at EHRA 2018, a European Society of Cardiology (ESC) congress.1 There were similar rates of stroke and bleeding, and an improvement in cognitive function was shown for the first time. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 20, 2018 Category: International Medicine & Public Health Source Type: news

Evaluation of a protocol for early detection of delayed brain hemorrhage in head injured patients on warfarin - Huang JL, Woehrle TA, Conway P, McCarty CA, Eyer MM, Eyer SD.
PURPOSE: In 2007, Essentia Health St. Mary's Medical Center (SMMC), a Level II trauma center in northeastern Minnesota, implemented a protocol for patients who presented with blunt head trauma and were receiving warfarin for anticoagulation. The purpose of... (Source: SafetyLit)
Source: SafetyLit - March 19, 2018 Category: International Medicine & Public Health Tags: TBI Source Type: news

Head injury on Warfarin: likelihood of delayed intracranial bleeding in patients with negative initial head CT - Afaneh A, Ford J, Gharzeddine J, Mazar A, Hayward RD, Buck J.
OBJECTIVE: To determine the likelihood that head injured patients on Warfarin with a negative initial head CT will have a positive repeat head CT. A retrospective chart review of our institution's trauma registry was performed for all patients admitted for... (Source: SafetyLit)
Source: SafetyLit - March 19, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Comunicado de la FDA sobre la seguridad de los medicamentos: Estudio de la FDA de pacientes de Medicare encontr ó menor riesgo de derrame cerebral y muerte con Pradaxa (dabigatrán) en comparación con warfarina
[05-13-2014] En su estudio en curso del anticoagulante Pradaxa (dabigatr án), la Administración de Alimentos y Medicamentos de Estados Unidos (FDA por sus sigla en inglés) completó recientemente un nuevo estudio en pacientes de Medicare en el que compara Pradaxa con un anticoagulante antiguo, warfarina (Coumadin, Jantoven y genéricos), para determinar el riesgo de a ccidente isquémico o derrame causado por un coágulo, hemorragia cerebral, hemorragia gastrointestinal severa, infarto de miocardio y muerte. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 26, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Drug Safety Communication: FDA study of Medicare patients finds risks lower for stroke and death but higher for gastrointestinal bleeding with Pradaxa (dabigatran) compared to warfarin
[05-13-2014] In its ongoing review of the blood thinner Pradaxa (dabigatran), the U.S. Food and Drug Administration (FDA) recently completed a new study in Medicare patients comparing Pradaxa to an older blood thinner, warfarin, for risk of ischemic or clot-related stroke, bleeding in the brain, major gastrointestinal (GI) bleeding, myocardial infarction (MI), and death. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 26, 2018 Category: Drugs & Pharmacology Source Type: news

Complications of lower extremity hematomas in patients with pre-injury warfarine use - Bukovcan P, Koller J.
INTRODUCTION: The aim of this paper is to ascertain the number of patients with pre-injury warfarin use who developed lower extremity hematomas treated in our facility, to analyse the data, used treatment methods and outcomes in these patients. PAT... (Source: SafetyLit)
Source: SafetyLit - February 19, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Lower ICH Mortality Rate With NOACs Than Warfarin Lower ICH Mortality Rate With NOACs Than Warfarin
A large real-world study provides some reassurance about the consequences of suffering an intracerebral hemorrhage when taking one of the new oral anticoagulants.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 13, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Intraocular Bleeding Risk Low With NOACs in Real-World Data (CME/CE)
(MedPage Today) -- Newer agents as safe as or safer than warfarin, other traditional agents (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 13, 2018 Category: Cardiology Source Type: news

FDA adds new information about warfarin INR test meters to FDA website to help patients, caregivers, and health care providers use these devices safely and effectively. https://go.usa.gov/xnHFk   #MedicalDevice
FDA adds new information about warfarin INR test meters to FDA website to help patients, caregivers, and health care providers use these devices safely and effectively. https://go.usa.gov/xnHFk  #MedicalDevice (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - February 12, 2018 Category: Medical Devices Authors: ( at FDADeviceInfo) Source Type: news

Warfarin Dosing in Cardiac Valve Replacement Warfarin Dosing in Cardiac Valve Replacement
This study identifies genetic polymorphisms which might be helpful for adjusting warfarin dosage to an effective and safe level in patients with cardiac valve replacement.Laboratory Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 12, 2018 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Coumadin vs. Plavix (Differences and Similarities)
Title: Coumadin vs. Plavix (Differences and Similarities)Category: MedicationsCreated: 2/1/2018 12:00:00 AMLast Editorial Review: 2/1/2018 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - February 1, 2018 Category: Cardiology Source Type: news

Dabigatran vs warfarin in NVAF: ERG risk score predicts cost
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - February 1, 2018 Category: Drugs & Pharmacology Source Type: news

ICH Survival Lower with Prior Anticoagulant Use
(MedPage Today) -- Still, risk lower with NOACS compared with warfarin (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - January 26, 2018 Category: Cardiology Source Type: news

Herbal Supplements May Be Dangerous When You Take Certain Prescription Drugs
A number of common herbal supplements, including green tea and Ginkgo biloba, can interact with prescription medications, according to a new research review published in the British Journal of Clinical Pharmacology. These interactions can make drugs less effective—and may even be dangerous or deadly. Doctors know that herbs can affect medication regimens, wrote the researchers, from the South African Medical Research Council, in their new paper. But because people often don’t disclose to their healthcare providers what over-the-counter drugs and supplements they’re taking, it’s difficult for scienti...
Source: TIME: Health - January 24, 2018 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized are herbal supplements safe are supplements safe drug interactions drug side effects green tea healthytime herbal drugs medicine onetime supplement safety warfarin Source Type: news

FDA Mini-Sentinel Assessment Confirms Safety and Effectiveness of XARELTO ® (rivaroxaban) and its Association with a Lower Risk of Ischemic Stroke vs. Warfarin
(Source: Johnson and Johnson)
Source: Johnson and Johnson - January 16, 2018 Category: Pharmaceuticals Source Type: news