Effectiveness of late coronary angioplasty in restoring sinus rhythm in inferior wall myocardial infarction with complete AV block
Coronary angiogram done with temporary pacemaker support showing a proximally occluded right coronary artery. AbstractAn elderly gentleman presenting late with inferior wall myocardial infarction and complete heart block underwent revascularization of an occluded proximal right coronary artery more than 4  days after the onset of symptoms and recovered sinus rhythm within 48 h of the procedure. There are no clear guidelines for time to percutaneous coronary intervention (PCI) in late-presenting myocardial infarction with complete atrioventricular blocks (CAVB), and studies looking at outcomes of primary PCI in this sit...
Source: Clinical Case Reports - April 27, 2024 Category: General Medicine Authors: Avitso Liegise, Lanu Naro Tags: CASE REPORT Source Type: research

Serum brain natriuretic peptide levels may be a useful marker for early diagnosis of cardiomyopathy secondary to neuroblastoma: A case report
A 5-month-old boy with neuroblastoma showed dilated cardiomyopathy. Key Clinical MessageCardiomyopathy is a rare but serious complication associated with neuroblastoma. The brain natriuretic peptide level led to a diagnosis of secondary dilated cardiomyopathy before the worsening of heart failure symptoms. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 27, 2024 Category: General Medicine Authors: Natsumi Fujiyama, Osamu Matsuo, Takahiro Yamashita, Kensaku Kohrogi, Fumiya Miyamura, Tadashi Anan, Kimitoshi Nakamura Tags: CASE REPORT Source Type: research

Single-center experience of thoracoscopic sympathectomy for palmar hyperhidrosis with long-term postoperative questionnaire survey
ConclusionsThoracoscopic sympathectomy is an effective surgical treatment for palmar hyperhidrosis. By contrast, the careful preoperative explanation of compensatory hyperhidrosis is considered to be very important. (Source: General Thoracic and Cardiovascular Surgery)
Source: General Thoracic and Cardiovascular Surgery - April 27, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research

Inversion recovery and saturation recovery pulmonary vein MR angiography using an image based navigator fluoro trigger and variable-density 3D cartesian sampling with spiral-like order
We describe its use in part during the global iodinated contrast shortage. VD-CASPR/iNAV framework was applied to ECG-gated inversion and saturation recovery gradient recalled echo PV CE-MRA in 65 patients (66 exams) using .15 mmol/kg Gadobutrol. Image quality was assessed by three physician s, and anatomical segmentation quality by two technologists. Left atrial SNR and left atrial/myocardial CNR were measured. 12 patients had CTA within 6 months of MRA. Two readers assessed PV ostial measurements versus CTA for intermodality/interobserver agreement. Inter-rater/intermodality reliabil ity, reproducibility of ostial meas...
Source: The International Journal of Cardiovascular Imaging - April 27, 2024 Category: Radiology Source Type: research

Evolving role of aortic valve calcification scoring – Time for opportunistic screening?
Aortic stenosis (AS) stands as the third most prevalent cardiovascular disease worldwide afflicting over 12% of individuals aged 75 and above, a figure projected to escalate alongside population aging trends. Its ramifications extend significantly to morbidity and mortality rates.1 The most common etiology is the fibrocalcific thickening of the aortic valve leaflets leading to progressive restricted leaflet opening, with less common causes being congenital bicuspid, rheumatic fever, and radiation. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - April 27, 2024 Category: Radiology Authors: Leandro Slipczuk, Philippe Pibarot, Piotr J. Slomka, Marc R. Dweck, Damini Dey Tags: Editorial Source Type: research

Echocardiographic assessment of cardiovascular involvements in children with cystic fibrosis
Cystic fibrosis (CF) is a fatal disease in which the cystic fibrosis transmembrane conductance regulator (CTFR) gene is mutated, resulting in defect in CFTR protein dependent sodium and chloride transport activity. It has been proved that Dysfunction of CFTR leads to imbalance in regulating the conduction of sodium and chloride ions in epithelial cell membranes and increased mucosal viscosity, which eventually leads to a variety of abnormalities such as pulmonary infection and gastrointestinal involvement [1,2]. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - April 27, 2024 Category: Respiratory Medicine Authors: Hosseinali Ghaffaripour, Ali Reza Norouzi, Maryam Hassanzad, Fariba Alaei, Mohammad Reza Khalilian, Hojjat Derakhshanfar, Nasrin Elahi Mehr Tags: Original Article Source Type: research

Association of soluble suppression of tumorigenicity 2 with mortality and adverse outcomes in chronic kidney disease: a systematic review and meta-analysis
ConclusionsHigh sST2 values are associated with an increased risk of all-cause mortality in pre-dialysis and dialysis patients, as well as with an elevated risk of cardiovascular mortality in the dialysis population. Further studies are needed to elucidate its potential association with cardiovascular events and kidney disease progression. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 27, 2024 Category: Urology & Nephrology Source Type: research

The additive prognostic value of end-systolic pressure-volume relation by stress CMR in patients with known or suspected coronary artery disease
ConclusionΔESPVR index by stress-CMR was independently associated with cardiac outcomes in patients with known/suspected CAD, in addition to replacement myocardial fibrosis and diabetes. Thus, the assessment of ΔESPVR index may be included into the standard stress-CMR exam to further stratify the patients. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - April 27, 2024 Category: Radiology Source Type: research

An integrated view of cisplatin-induced nephrotoxicity, hepatotoxicity, and cardiotoxicity: characteristics, common molecular mechanisms, and current clinical management
AbstractCisplatin (CP) is a chemotherapy drug widely prescribed to treat various neoplasms. Although fundamental for the therapeutic action of the drug, its cytotoxic mechanisms trigger adverse effects in several tissues, such as the kidney, liver, and heart, which limit its clinical use. In this sense, studies point to an essential role of damage to nuclear and mitochondrial DNA associated with oxidative stress, inflammation, and apoptosis in the pathophysiology of tissue injuries. Due to the limitation of effective preventive and therapeutic measures against CP-induced toxicity, new strategies with potential cytoprotecti...
Source: Clinical and Experimental Nephrology - April 27, 2024 Category: Urology & Nephrology Source Type: research

An 11-month-old boy with tuberculous meningitis presenting as progressive limb weakness, fever, developmental retardation, and loss of consciousness: a case report
ConclusionOver half of treated TB meningitis patients die or suffer severe neurological sequelae, mainly due to late diagnosis. Hence, early diagnosis and prompt initiation of TB treatment offer the best chance of a good neurological outcome. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - April 27, 2024 Category: General Medicine Source Type: research

Ketogenic Diets Hold Therapeutic Potential Against Periodontal Inflammation
AbstractPurpose of ReviewPeriodontitis, one of the most prevalent diseases in the world, is caused by the accumulation of dysbiotic microbial biofilm on the teeth leading to chronic inflammation of the tissues surrounding the teeth. Type 2 diabetes mellitus (T2DM), obesity, chronic stress, and smoking are some of the risk factors for the disease. A high-carbohydrate diet also increases the risk of periodontal inflammation. Modifying diet and nutrition could serve as a preventive and therapeutic tool to target multiple risk factors simultaneously.Recent FindingsEmerging evidence shows that the ketogenic diet induces hormeti...
Source: Current Oral Health Reports - April 27, 2024 Category: Dentistry Source Type: research

The relationship between serum manganese concentration with all-cause and cause-specific mortality: a retrospective and population-based cross-sectional study
The study aimed to explore the association between manganese concentration and all-cause, cardiovascular disease (CVD)-related, and cancer-related mortality in the general population of the United States. (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 27, 2024 Category: Cardiology Authors: Jianyun Ou, Yunfei Sun, Jie Tong, Weihong Tang and Genshan Ma Tags: Research Source Type: research

Bioactive adrenomedullin as a marker of congestion and disease progression in patients with a systemic right ventricle
Adults with a systemic right ventricle (sRV) are at a high risk for heart failure (HF) hospitalisation and mortality. Bioactive adrenomedullin (bio-ADM) has been proposed as a marker of congestion and prognosis in patients with cardiovascular disease. We aimed to evaluate the association between bio-ADM and mortality and HF events in sRV patients. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 27, 2024 Category: Cardiology Authors: Mohammad Mostafa Ansari Ramandi, Paul M. Hendriks, Adriaan A. Voors, Annemien E. van den Bosch, Joost P. van Melle Source Type: research

Diagnostic value of LGE and T1 mapping in multiple myeloma patients ’heart
Unidentified heart failure occurs in patients with multiple myeloma when their heart was involved. CMR with late gadolinium enhancement (LGE) and T1 mapping can identify myocardial amyloid infiltrations. (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 27, 2024 Category: Cardiology Authors: Qian Cui, Jing Yu, Xihong Ge, Guangfeng Gao, Yang Liu, Qiang He and Wen Shen Tags: Research Source Type: research

Immunological Aspects of Kabuki Syndrome: A Retrospective Multicenter Study of the Italian Primary Immunodeficiency Network (IPINet)
In conclusion, immunological manifestations of KS in our cohort include susceptibility to infections, antibody deficiency, and autoimmunity. Autoimmune cytopenia is correlated with thymectomy and elevated CD3  + TCRαβ + CD4-CD8-T-cells, and benefits from treatment with mycophenolate. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - April 27, 2024 Category: Allergy & Immunology Source Type: research