Management of dyslipidemia after atherosclerotic cardiovascular event: Still a long way to go …and we know it
Low-density lipoprotein cholesterol (LDL-C) and cholesterol-rich apolipoprotein-B-containing lipoproteins play a central role in atherogenesis when retained and modified within the arterial wall [1]. The log-linear direct relationship between circulating LDL-C levels and the risk of atherosclerotic cardiovascular disease (ASCVD) has been robustly validated in numerous randomized controlled trials, observational studies, epidemiological studies, and Mendelian randomization studies [2 –4]. Patients who have experienced a cardiovascular event are at a high risk for future events, and optimal LDL-C management, along with lif...
Source: International Journal of Cardiology - March 18, 2024 Category: Cardiology Authors: Josip Andelo Borovac, Domenico D'Amario Source Type: research

Comparative effectiveness of endovascular treatment modalities for de novo femoropopliteal lesions at long-term follow-up: A network meta-analysis of randomized controlled trials
To evaluate the best endovascular treatment for de novo femoropopliteal lesions at long-term follow-up through network meta-analysis of randomized controlled trials. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 17, 2024 Category: Cardiology Authors: Yang Zhou, Tun Wang, Hao He, Quanming Li, Zicheng Wan, Peng Lu, Chang Shu Source Type: research

Management of prosthetic valve thrombosis with unfractionated heparin
This study aimed to assess the results of UFH in patients diagnosed with both obstructive and non-obstructive PVT. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 17, 2024 Category: Cardiology Authors: Semih Kalkan, Mustafa Ozan G ürsoy, Ahmet Güner, Macit Kalçık, Emrah Bayam, Sabahattin Gündüz, Mehmet Özkan Source Type: research

Commentary - neurogenic mechanisms in arrhythmogenic cardiomyopathy
Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease characterized by fibrofatty myocardial replacement that underlies structural and functional ventricular abnormalities and life-threatening ventricular arrhythmias potentially responsible for sudden cardiac death (SCD) [1,2]. The original disease phenotype characterized by a predominant right ventricular (RV) involvement was termed ‘arrhythmogenic right ventricular cardiomyopathy’ (ARVC) [1]; however, the increasing identification of biventricular and left-dominant [also referred to as ‘arrhythmogenic left ventricular cardiomyopathy’ (ALVC)] forms has led...
Source: International Journal of Cardiology - March 17, 2024 Category: Cardiology Authors: Domenico Corrado, Francesca Graziano, Alessandro Zorzi Source Type: research

Role of experience in Myectomy for hypertrophic cardiomyopathy: With very high procedural volume, Myectomy remains low-risk even with concomitant procedure need
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy, affecting an estimated 1/200 to 1/500 people. [1] Dynamic left ventricular outflow tract (LVOT) is present in the majority of patients with HCM, either at rest or with provocation. Dynamic LVOT obstruction is a major cause of symptoms, is associated with worse outcomes, and remains the primary therapeutic target in the treatment of obstructive HCM. [2] In patients with medically refractory symptoms related to dynamic LVOT obstruction, advanced therapies, including septal reduction therapy (SRT), are recommended. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 16, 2024 Category: Cardiology Authors: Jeffrey B. Geske, Hartzell V. Schaff Source Type: research

Insights into uremic cardiomyopathy and cardiac remodeling following kidney transplantation: A call for further research
Since its first description in 1967, uremic cardiomyopathy (UC) has undergone successive redefinitions attributable to advancements in multimodal imaging techniques. [1]. It comprises left ventricular (LV) hypertrophy associated with increased arterial stiffness, thickening of the LV walls, as well as coronary artery atherosclerosis and calcification. It represents a clinical phenotype of cardiovascular disease that accompanies chronic kidney disease (CKD), with a wide range of contributing factors. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 16, 2024 Category: Cardiology Authors: Mariana Floria, Diana-Elena Floria, Daniela Maria T ănase Source Type: research

Native coronary artery or bypass graft percutaneous coronary intervention in patients after previous coronary artery bypass surgery: A large nationwide analysis from the Netherlands Heart Registration
Patients with previous coronary artery bypass surgery (CABG) who require repeat revascularization frequently undergo percutaneous coronary intervention (PCI). We sought to identify factors associated with the decision to intervene on the native vessel versus a bypass graft and investigate their outcomes in a large nationwide prospective registry. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 15, 2024 Category: Cardiology Authors: Frans J. Beerkens, I. Tarik K üçük, Anna van Veelen, Robert A.F. de Lind van Wijngaarden, Marijke J.C. Timmermans, Roxana Mehran, George Dangas, Robert Klautz, Jose P.S. Henriques, Bimmer E.P.M. Claessen, on behalf of the PCI and Cardiothoracic Surgery Source Type: research

Thin-cap fibroatheroma in acute coronary syndrome: Implication for intravascular imaging assessment
Acute coronary syndrome (ACS), a significant cardiovascular disease threat, has garnered increased focus concerning its etiological mechanisms. Thin-cap fibroatheroma (TCFA) are central to ACS pathogenesis, characterized by lipid-rich plaques, profuse foam cells, cholesterol crystals, and fragile fibrous caps predisposed to rupture. While TCFAs may be latent and asymptomatic, their pivotal role in ACS risk is undeniable. High-resolution imaging techniques like Optical coherence tomography (OCT) and Intravascular ultrasound (IVUS) are instrumental for effective TCFA detection. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 14, 2024 Category: Cardiology Authors: Chaozhong Li, Chancui Deng, Bei Shi, Ranzun Zhao Source Type: research

Editorial Board
(Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 13, 2024 Category: Cardiology Source Type: research

Stress-first always to properly perform stress-only: A historical perspective to mark the end of the story
Not many years ago, there was still a debate about the best sequence for performing myocardial perfusion imaging. The traditional rest-stress approach was preferred by many centers for its simplicity and the advantage of acquiring the stress part with the higher dose in case of single day protocol [1]. With time, however, it became apparent that an increasing percentage of patients did not show stress-induced perfusion defects, so that after a normal stress study rest images were not required [2]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 13, 2024 Category: Cardiology Authors: Roberto Sciagr à, Elisabetta M. Abenavoli Source Type: research

Letter to the Editor: “Changes in walking speed 6 months after discharge may be more sensitive to subsequent prognosis than handgrip strength in patients hospitalized for heart failure”
We read the article with great interest by Satoru Hanada, et al. “Changes in walking speed 6 months after discharge may be more sensitive to subsequent prognosis than handgrip strength in patients hospitalized for heart failure [1]”. Based on the results of the research, the authors found that Changes in WS were related to HF prognosis, suggesting that chan ges in WS may be more sensitive to further risk stratification than changes in HGS. We appreciate the insightful observations and conclusions presented. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 13, 2024 Category: Cardiology Authors: Lou Chao-chen Source Type: research

Patterns of atrial fibrillation, relevant cardiac structural and functional changes predict functional and cognitive outcomes in patients with ischemic stroke and atrial fibrillation
Atrial fibrillation (AF) pattern, relevant cardiac changes are important predictors of outcomes in AF, but their impact on patients with ischemic stroke and AF remained unclear. We aimed to explore the impact of AF patterns, cardiac structural and functional markers on long-term functional and cognitive outcomes in ischemic stroke patients with AF. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 13, 2024 Category: Cardiology Authors: Jiahuan Guo, Dandan Wang, Jiaokun Jia, Jia Zhang, Yanfang Liu, Jingjing Lu, Ying Tian, Xingquan Zhao Source Type: research

Increased aortic pressures and pulsatile afterload components promote concentric left ventricular remodeling in adults with transposition of the great arteries and arterial switch operation
Functional abnormalities of the ascending aorta (AA) have been mainly reported in young patients who underwent arterial switch operation (ASO) for transposition of the great arteries (TGA). (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 13, 2024 Category: Cardiology Authors: Zahra Belhadjer, Magalie Ladouceur, Gilles Soulat, Antoine Legendre, Umit Gencer, Thomas Dietenbeck, Laurence Iserin, Lucile Houyel, Damien Bonnet, Elie Mousseaux Source Type: research

Artificial intelligence: The future for multimodality imaging of right ventricle
The crucial pathophysiological and prognostic roles of the right ventricle in various diseases have been well-established. Nonetheless, conventional cardiovascular imaging modalities are frequently associated with intrinsic limitations when evaluating right ventricular (RV) morphology and function. The integration of artificial intelligence (AI) in multimodality imaging presents a promising avenue to circumvent these obstacles, paving the way for future fully automated imaging paradigms. This review aimed to address the current challenges faced by clinicians and researchers in integrating RV imaging and AI technology, to p...
Source: International Journal of Cardiology - March 13, 2024 Category: Cardiology Authors: Yuhan Qin, Xiaohan Qin, Jing Zhang, Xiaoxiao Guo Source Type: research

Renal impairment and outcome in Takotsubo syndrome: Insights from a national multicentric cohort
Data on the association between kidney function and Takotsubo syndrome (TTS) outcomes are scarce and conflictive. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 13, 2024 Category: Cardiology Authors: Ravi Vazirani, Manuel Almendro Delia, Emilia Blanco-Ponce, Agust ín C. Martín-García, Clara Fernández-Cordón, Aitor Uribarri, Mireia Andrés, Oscar Vedia, Alessandro Sionis, Miguel Corbí-Pascual, Jorge Salamanca, Alberto Pérez-Castellanos, José Da Source Type: research