Trends in percutaneous left atrial appendage occlusion and 1-year mortality 2013 –2021: A nationwide observational study
Percutaneous left atrial appendage occlusion (LAAO) is increasingly used for stroke prevention in patients with atrial fibrillation and anticoagulant-related complications. Yet, real-life studies evaluating changes in patient characteristics and indications for LAAO remain scarce. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 26, 2024 Category: Cardiology Authors: Olivia J. Madsen, Morten Lamberts, Jonas B. Olesen, Morten L. Hansen, Thomas K ümler, Erik L. Grove, Niels H. Andersen, Emil Fosbøl, Ole De Backer, Jarl E. Strange Source Type: research

Circulating progenitor cells and coronary collaterals in chronic Total occlusion
The role of circulating progenitor cells (CPC) in collateral formation that occurs in the presence of chronic total occlusions (CTO) of a coronary artery is not well established. In stable patients with a CTO, we investigated whether CPC levels are associated with (a) collateral development and (b) ischemic burden, as measured by circulating high sensitivity troponin-I (hsTn-I) levels. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 25, 2024 Category: Cardiology Authors: Daniel A. Gold, Pratik B. Sandesara, Bryan Kindya, Matthew E. Gold, Vardhmaan Jain, Nishant Vatsa, Shivang R. Desai, Adithya Yadalam, Alexander Razavi, Malika Elhage Hassan, Yi-An Ko, Chang Liu, Ayman Alkhoder, Alireza Rahbar, Mohammad S. Hossain, Edmund Source Type: research

Predictive nomogram for 28-day mortality risk in mitral valve disorder patients in the intensive care unit: A comprehensive assessment from the MIMIC-III database
Mitral valve disorder (MVD) stands as the most prevalent valvular heart disease. Presently, a comprehensive clinical index to predict mortality in MVD remains elusive. The aim of our study is to construct and assess a nomogram for predicting the 28-day mortality risk of MVD patients. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 25, 2024 Category: Cardiology Authors: Yuxin Qiu, Menglei Li, Xiubao Song, Zihao Li, Ao Ma, Zhichao Meng, Yanfei Li, Minghui Tan Source Type: research

Prognostic value of left ventricular and left atrial strain imaging in moderate to severe aortic stenosis: Insights from an Asian population
Data regarding the prognostic value of left atrial (LA) strain in aortic stenosis (AS) is scarce, especially in Asian population and moderate AS. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 25, 2024 Category: Cardiology Authors: Chung-Yen Lee, Chieh-Mei Tsai, Kuang-Chien Chiang, Chi-Ching Huang, Mao-Shin Lin, Chung-Lieh Hung, Yi-Lwun Ho, Vuyisile T. Nkomo, Masaaki Takeuchi, Li-Tan Yang Source Type: research

Implication of geriatric nutritional risk index on treatment response and long-term prognosis in patients with cardiac resynchronization therapy
This study aims to explore the clinical implication of GNRI on treatment response and long-term clinical outcomes in heart failure (HF) patients receiving cardiac resynchronization therapy (CRT). (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 24, 2024 Category: Cardiology Authors: Hao Huang, Bingqi Fu, Tianxin Long, Yu Yu, Sijing Cheng, Min Gu, Chi Cai, Xuhua Chen, Hongxia Niu, Wei Hua Source Type: research

LKB1 inhibits the phenotypic transformation of vascular smooth muscle cells by activating SIRT6
Most recently, Chen et al. reported that vascular smooth muscle cell (VSMC)-specific overexpression of LKB1 in atherosclerotic mice inhibited the phenotypic transition of VSMCs and alleviated lipid accumulation within plaques, leading to the mitigation of atherogenesis [1]. This finding demonstrates the critical role of LKB1 in the phenotypic transformation of VSMCs and atherosclerosis, whereas the underlying mechanisms need further investigation. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 24, 2024 Category: Cardiology Authors: Lin Zhu, Yu-Ping Wang, Xiao-Dan Xu, Xi Xu, Fu-Rong Shao, Kun Ren Source Type: research

Intracoronary physiology: Easier to measure, but still complex. The art of interpreting intracoronary pressure wire data.
Since the introduction of fractional flow reserve (FFR) [1], coronary physiology has progressively gained prominence in coronary diagnosis and intervention. Its implementation has led to improved outcomes, safely avoiding unnecessary revascularisations without increasing or even decreasing the number of adverse events. Recently, FFR has facilitated a new approach to understanding ischemic heart disease, explaining its symptoms and consequences beyond coronary stenoses [2]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Ram ón López-Palop, Pilar Carrillo, Alfonso Freites Source Type: research

Insights on challenges in multi-biomarker strategy for efficient risk stratification in patients with chest pain at the emergency department
Patients with acute chest pain are frequently treated in emergency departments, with (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Kenji Inoue Source Type: research

Prevalence, mortality, cost, and disparities in transcatheter mitral valve repair and replacement in cancer patients: Artificial intelligence and propensity score national 5-year analysis of 7495 procedures
We conducted the first comprehensive evaluation of the therapeutic value and safety profile of transcatheter mitral edge-to-edge repair (TEER) and transcatheter mitral valve replacement (TMVR) in individuals concurrently afflicted with cancer. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Konstantinos Marmagkiolis, Dominique J. Monlezun, Jaime Caballero, Mehmet Cilingiroglu, Matthew N. Brown, Vlasis Ninios, Ali Abdelrahman, Cezar A. Iliescu Source Type: research

Predictive value of plaque characteristics for identification of lesions causing ischemia
This study aimed to investigate the association between FFR and plaque characteristics assessed using coronary CTA and OCT for intermediate coronary stenosis. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Yong-Joon Lee, Geunhee Park, Seul-Gee Lee, Yun-Kyeong Cho, Hyuck Jun Yoon, Ung Kim, Ji-Yong Jang, Seung-jin Oh, Seung-Jun Lee, Sung-Jin Hong, Chul-Min Ahn, Byeong-Keuk Kim, Hyuk-Jae Chang, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang, Jung-Su Source Type: research

Stronger positive correlation of the left ventricular mass index and extracellular volume fraction with diastolic function in diabetic patients without myocardial infarction
The structural and functional characteristics of the heart in patients with diabetes mellitus (DM) and without myocardial infarction (MI) are not fully understood. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Hiroyuki Miura, Masahiro Koseki, Seiko Ide, Yasuhide Asaumi, Yoshiaki Morita, Yasutoshi Ohta, Katsunao Tanaka, Takeshi Okada, Takashi Omatsu, Soshiro Ogata, Tetsuya Fukuda, Yasushi Sakata, Teruo Noguchi Source Type: research

The role of left ventricular global work index on the prediction of cardiovascular mortality after transcatheter aortic valve implantation
Echocardiography is used for assessment of patients after transcatheter aortic valve implantation (TAVI). In Anwer's study [1], they aimed to investigate whether the Global work index (GWI) integrates LV deformation may be advantageous for long-term follow-up. In the multivariable Cox regression of this study, they found that the GWI independently improved an LV systolic function model including LV ejection fraction (LVEF) and global longitudinal strain (GLS). Similarly, GWI but not LVEF independently improved the outcome association of different clinical models. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Bing Chen, Qinggang Zhang Source Type: research

Ascending aortic dilatation in TAVI: Actor or bystander?
Ascending aorta dilatation (AAD) frequently coexist with aortic stenosis (AS), affecting approximately 20% of patients undergoing surgical (SAVR) or transcatheter aortic valve replacement (TAVR) [1 –3] This association is even stronger in patients with bicuspid aortic valve (BAV), showing AAD in up to 42% [4]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Gabriela Tirado-Conte, Ana Pardo Sanz, Luisa Salido Tahoces Source Type: research

Is the detection of late gadolinium enhancement sufficient for assessing fibrosis in cardiomyopathies?
In recent years Cardiac magnetic resonance (CMR) imaging has become a fundamental tool for evaluating patients with Dilated Cardiomyopathy (DCM). Indeed, CMR has revolutionized the diagnostic approach to different cardiomyopathies, not only providing detailed information about ventricular dimension and function but also allowing visualization and quantification of scarring using late gadolinium enhancement (LGE) [1]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Marika Martini, Barbara Bauce Source Type: research

Growth differentiation factor-1  5 and metabolic features in chronic heart failure: Insights from the SUPPORT Trial -GDF15 across the BMI spectrum
GDF15 plays pivotal metabolic roles in nutritional stress and serves as a physiological regulator of energy balance. However, the patterns of GDF15 levels in underweight or obese patients with chronic heart failure (CHF) are not well-understood. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Kanako Teramoto, Kotaro Nochioka, Yasuhiko Sakata, Eri Toda Kato, Kunihiro Nishimura, Hiroaki Shimokawa, Satoshi Yasuda, SUPPORT Trial Investigators Source Type: research