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CT coronary angiography: Is it the new standard in coronary assessment for liver transplant candidates?
Cardiovascular events continue to impact post-liver transplant survival [1]. Although the etiologies of these cardiac events are multifactorial, the presence of significant coronary artery disease can contribute to a patient's ability to tolerate the multifactorial stressors and physiological insults that occur throughout the transplantat process [2]. In addition, cardiovascular death is predominant in the post-liver transplant population, with sudden cardiac death contributing to 1 out of 3 post-transplant cardiac mortalities [3]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 2, 2024 Category: Cardiology Authors: Ryan Mukesh Chadha Source Type: research

New era in right ventricular imaging with AI: Challenges and horizons
The intricate anatomy and complex physiological functions of the right ventricle (RV) have historically positioned it as a challenging area within cardiovascular imaging and diagnostics. Traditional imaging modalities, while foundational to the early understanding and assessment of cardiac function, often fall short in accurately delineating the unique morphology and dynamic behavior. This discrepancy arises from the crescent-shaped structure, extensive trabeculations, and the pivotal role it plays in pulmonary circulation and systemic venous return, all of which demand more sophisticated imaging solutions [1,2]. (Source: ...
Source: International Journal of Cardiology - April 2, 2024 Category: Cardiology Authors: Kenya Kusunose Source Type: research

Levosimendan in cardiac amyloidosis: Unveiling promising paths
Cardiac amyloidosis (CA) is a progressive infiltrative disease primarily caused by the accumulation of misfolded, cleaved, and aggregated proteins in the extracellular space of the myocardium. CA leads to heart failure as the most frequent clinical manifestation. In recent years, research have focused on identifying and developing disease-modifying targeted therapies for CA. These efforts have resulted in improved prognosis, particularly in the setting of transthyretin CA. However, there has been less scientific interest in investigating the treatment and prompt management of patients with CA hospitalized for acute heart f...
Source: International Journal of Cardiology - April 1, 2024 Category: Cardiology Authors: Andrea Faggiano, Stefano Carugo, Gianfranco Sinagra, Marco Merlo Source Type: research

Use of apixaban in adults with congenital heart disease and atrial arrhythmias: The PROTECT-AR study
Adults with congenital heart disease (ACHD) and atrial arrhythmias (AA) face an increased risk of thromboembolic events. Limited data exist on the use of non-vitamin K oral anticoagulants for thromboprophylaxis in ACHD. We aimed to assess the effectiveness and safety of apixaban in ACHD patients with AA. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 30, 2024 Category: Cardiology Authors: Anastasios Kartas, Andreas S. Papazoglou, Dimitrios V. Moysidis, Stefanos Despotopoulos, Amalia Baroutidou, Diamantis Kosmidis, Athanasios Koutsakis, Sotiria Liori, Sotiria Apostolopoulou, Alexandra Frogoudaki, Afrodite Tzifa, Apostolos Galatas, Georgios Source Type: research

Aortopathy and aortic valve surgery in patients with bicuspid aortic valve with and without raphe
To evaluate the association between raphe in bicuspid aortic valve (BAV) patients and valve dysfunction, aortopathy and aortic valve surgery in the REBECCA registry [REgistro della valvola aortica Bicuspide della Societ à Italiana di ECocardiografia e CArdiovascular Imaging (SIECVI)]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 30, 2024 Category: Cardiology Authors: Michele Bellino, Francesco Antonini-Canterin, Eduardo Bossone, Pompilio Faggiano, Fabio Chirillo, Salvatore La Carrubba, Giorgio Faganello, Moreno Cecconi, Concetta Zito, Nicol ò Dasseni, Stefano Nistri, Antonella Moreo, Iacopo Fabiani, Giacomo Faden, Fr Source Type: research

Impact of breast-, gastrointestinal-, and lung cancer on prognosis in patients with first-time pulmonary embolism: A Danish nationwide cohort study
This study investigated, the 1-year prognosis following PE in patients with breast-, gastrointestinal-, or lung cancer stratified by cancer status. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 30, 2024 Category: Cardiology Authors: Nina Nouhravesh, Jarl E. Strange, Caroline Sindet-Pedersen, Anders Holt, Jacob T ønnesen, Camilla Fuchs Andersen, Sebastian K. Nielsen MBsc, Erik L. Grove, Dorte Nielsen, Morten Schou, Morten Lamberts Source Type: research

Fixed-dose combination therapy in pulmonary arterial hypertension: Pros & cons
Quality of life of patients suffering from chronic diseases is inevitably conditioned by the number of pills taken during the day. To improve patients' tolerability, compliance and quality of life and reduce healthcare costs, pharmaceutical companies are focusing on the commercialization of fixed-dose combination (FDC) therapies.The last ESC/ERS guidelines for the treatment of pulmonary arterial hypertension (PAH) recommend initial dual combination therapy for newly diagnosed patients at low or intermediate mortality risk. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 30, 2024 Category: Cardiology Authors: Giovanna Manzi, Tommaso Recchioni, Roberto Badagliacca, Silvia Papa, Carmine Dario Vizza Source Type: research

Contemporary outcomes of surgical aortic valve replacement in patients referred for a transcatheter approach
The purpose of this study is to examine which patients referred to our structural valve clinic for potential transcatheter aortic valve replacement (TAVR) are receiving surgical aortic valve replacement (SAVR) whether due to unsuitable anatomy for TAVR versus other reasons. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 30, 2024 Category: Cardiology Authors: Stephane Leung Wai Sang, Caleb Weissman, Jessica Parker, Tomasz Timek, Charles Willekes, Justin Fanning Source Type: research

Predictors of adverse cardiac events of coronary myocardial bridging diagnosed with computed tomography angiography
Myocardial bridging (MB) is a frequent congenital anomaly of the epicardial coronary arteries commonly considered a benign condition. However, in some cases a complex interplay between anatomical, clinical and physiology factors may lead to adverse events, including sudden cardiac death. Coronary CT angiography (CCTA) emerged as the gold standard noninvasive imaging technique for the evaluation of MB. Aim of the study was to evaluate MB prevalence and anatomical features in a large population of patients who underwent CCTA for suspected CAD and to identify potential anatomical and clinical predictors of adverse cardiac eve...
Source: International Journal of Cardiology - March 29, 2024 Category: Cardiology Authors: Daniele Andreini, Edoardo Conte, Giovanni Monizzi, Blanca Prestini, Angelo Ratti, Marta Belmonte, Eleonora Melotti, Marco Doldi, Davide Marchetti, Matteo Schillaci, Flavia Nicoli, Angelo Mastrangelo, Pasquale Paolisso, Carlo Gigante, Maria Laura Novembre, Source Type: research

Patterns of aortic valve replacement in Europe and adoption by sex
This study aimed to describe patterns of aortic valve replacement (AVR) for severe AS across Europe, including stratification by sex. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 28, 2024 Category: Cardiology Authors: Sabine Bleiziffer, Clare Appleby, Victoria Delgado, Helene Eltchaninoff, Catherine Gebhard, Christian Hengstenberg, Wojtek Wojakowski, Nathan Petersen, Jana Kurucova, Peter Bramlage, Tanja K. Rudolph Source Type: research

Fluid-filled versus sensor-tipped pressure guidewires for FFR and Pd/Pa measurement; PW-COMPARE study
This study aimed to compare simultaneous pressure measurements with fluid-filled and sensor-tipped pressure guidewires. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 28, 2024 Category: Cardiology Authors: Rob Eerdekens, Pim A.L. Tonino, Frederik M. Zimmermann, Koen Teeuwen, Pieter-Jan Vlaar, Guus A. de Waard, Niels van Royen, Lokien X. van Nunen Source Type: research

Temporal progression of replacement and interstitial fibrosis in optimally managed dilated cardiomyopathy patients: A prospective study
Background: To prospectively examine the dynamic evolution of fibrotic processes within a one-year in patients with dilated cardiomyopathy (DCM). Methods: Between May 2019 and September 2020, 102 DCM patients (mean age 45.2  ± 11.8 years, EF 29.9 ± 11.6%) underwent cardiac magnetic resonance (CMR-1). After 13.9 ± 2.9 months, 92 of these patients underwent a follow-up CMR (CMR-2). Replacement fibrosis was assessed via late gadolinium enhancement (LGE), quantified in terms of LGE mass and extent. Inter stitial fibrosis was evaluated via T1-mapping and expressed as extracellular volume fraction (ECV). (Sour...
Source: International Journal of Cardiology - March 26, 2024 Category: Cardiology Authors: Pawel Rubi ś, Paweł Banyś, Maciej Krupiński, Małgorzata Mielnik, Sylwia Wiśniowska-Śmiałek, Ewa Dziewięcka, Małgorzata Urbańczyk-Zawadzka Source Type: research

Comment on “Subclinical myocardial injury increases the risk of heart failure in patients with and without type 2 diabetes post-acute coronary syndrome”
In this study, 50 acute coronary syndrome (ACS) patients who underwent revascularization were prospectively enrolled, and the univariate analysis was used for the evaluation of the effect of subclinical myocardial injury (sMi) on heart failure risk after ACS. They found and concluded that the sMi increased the risk of heart failure after ACS, irrespective of diabetes status. However, we raise some statistical concerns which could change the conclusion of this study. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 23, 2024 Category: Cardiology Authors: Yun Cheng, Qinggang Zhang Source Type: research

Machine learning to identify a composite indicator to predict cardiac death in ischemic heart disease
Machine learning (ML) employs algorithms that learn from data, building models with the potential to predict events by aggregating a large number of variables and assessing their complex interactions. The aim of this study is to assess ML potential in identifying patients with ischemic heart disease (IHD) at high risk of cardiac death (CD). (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 23, 2024 Category: Cardiology Authors: Alessandro Pingitore, Chenxiang Zhang, Cristina Vassalle, Paolo Ferragina, Patrizia Landi, Francesca Mastorci, Rosa Sicari, Alessandro Tommasi, Cesare Zavattari, Giuseppe Prencipe, Alina S îrbu Source Type: research

Enhancing walking performance in patients with peripheral arterial disease: An intervention with ankle-foot orthosis
This study aimed to employ advanced biomechanical gait analysis to evaluate the impact of AFO intervention on gait performance among patients with PAD. Patients with claudication had hip, knee, and ankle joint kinetics and kinematics assessed using a cross-over intervention design. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 23, 2024 Category: Cardiology Authors: Farahnaz Fallahtafti, Kaeli Samson, Zahra Salamifar, Jason Johanning, Iraklis Pipinos, Sara A. Myers Source Type: research