The influence of false interoceptive feedback on emotional state and balance responses to height-induced postural threat
Biol Psychol. 2024 Apr 23:108803. doi: 10.1016/j.biopsycho.2024.108803. Online ahead of print.ABSTRACTPostural threat elicits a robust emotional response (e.g., fear and anxiety about falling), with concomitant modifications in balance. Recent theoretical accounts propose that emotional responses to postural threats are manifested, in part, from the conscious monitoring and appraisal of bodily signals ('interoception'). Here, we empirically probe the role of interoception in shaping emotional responses to a postural threat by experimentally manipulating interoceptive cardiac feedback. Sixty young adults completed a single ...
Source: Biological Psychology - April 25, 2024 Category: Psychiatry & Psychology Authors: Mathew W Hill Ellie Johnson Toby J Ellmers Source Type: research

Greenspaces And Cardiovascular Health
Circ Res. 2024 Apr 26;134(9):1179-1196. doi: 10.1161/CIRCRESAHA.124.323583. Epub 2024 Apr 25.ABSTRACTAccumulating evidence suggests that living in areas of high surrounding greenness or even brief exposures to areas of high greenery is conducive to cardiovascular health, which may be related to the environmental, social, psychological, and physiological benefits of greenspaces. Recent data from multiple cross-sectional, longitudinal, and cohort studies suggest that living in areas of high surrounding greenness is associated with a lower risk of all-cause and cardiovascular mortality. High levels of neighborhood greenery ha...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Rachel J Keith Joy L Hart Aruni Bhatnagar Source Type: research

Heat and Cardiovascular Mortality: An Epidemiological Perspective
Circ Res. 2024 Apr 26;134(9):1098-1112. doi: 10.1161/CIRCRESAHA.123.323615. Epub 2024 Apr 25.ABSTRACTAs global temperatures rise, extreme heat events are projected to become more frequent and intense. Extreme heat causes a wide range of health effects, including an overall increase in morbidity and mortality. It is important to note that while there is sufficient epidemiological evidence for heat-related increases in all-cause mortality, evidence on the association between heat and cause-specific deaths such as cardiovascular disease (CVD) mortality (and its more specific causes) is limited, with inconsistent findings. Exi...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Nidhi Singh Ashtyn Tracy Areal Susanne Breitner Siqi Zhang Stefan Agewall Tamara Schikowski Alexandra Schneider Source Type: research

Impact of Wildfires on Cardiovascular Health
Circ Res. 2024 Apr 26;134(9):1061-1082. doi: 10.1161/CIRCRESAHA.124.323614. Epub 2024 Apr 25.ABSTRACTWildfire smoke (WFS) is a mixture of respirable particulate matter, environmental gases, and other hazardous pollutants that originate from the unplanned burning of arid vegetation during wildfires. The increasing size and frequency of recent wildfires has escalated public and occupational health concerns regarding WFS inhalation, by either individuals living nearby and downstream an active fire or wildland firefighters and other workers that face unavoidable exposure because of their profession. In this review, we first sy...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Victoria A Williams Luke R Perreault Charbel T Yazbeck Nicholas A Micovic Jessica M Oakes Chiara Bellini Source Type: research

Environmental Impacts on Cardiovascular Health and Biology: An Overview
Circ Res. 2024 Apr 26;134(9):1048-1060. doi: 10.1161/CIRCRESAHA.123.323613. Epub 2024 Apr 25.ABSTRACTEnvironmental stressors associated with human activities (eg, air and noise pollution, light disturbance at night) and climate change (eg, heat, wildfires, extreme weather events) are increasingly recognized as contributing to cardiovascular morbidity and mortality. These harmful exposures have been shown to elicit changes in stress responses, circadian rhythms, immune cell activation, and oxidative stress, as well as traditional cardiovascular risk factors (eg, hypertension, diabetes, obesity) that promote cardiovascular d...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Jacob R Blaustein Matthew J Quisel Naomi M Hamburg Sharine Wittkopp Source Type: research

Personal Strategies to Reduce the Cardiovascular Impacts of Environmental Exposures
Circ Res. 2024 Apr 26;134(9):1197-1217. doi: 10.1161/CIRCRESAHA.123.323624. Epub 2024 Apr 25.ABSTRACTUbiquitous environmental exposures increase cardiovascular disease risk via diverse mechanisms. This review examines personal strategies to minimize this risk. With regard to fine particulate air pollution exposure, evidence exists to recommend the use of portable air cleaners and avoidance of outdoor activity during periods of poor air quality. Other evidence may support physical activity, dietary modification, omega-3 fatty acid supplementation, and indoor and in-vehicle air conditioning as viable strategies to minimize a...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Luke J Bonanni Jonathan D Newman Source Type: research

Heavy Metal Exposure and Cardiovascular Disease
Circ Res. 2024 Apr 26;134(9):1160-1178. doi: 10.1161/CIRCRESAHA.123.323617. Epub 2024 Apr 25.ABSTRACTHeavy metals are harmful environmental pollutants that have attracted widespread attention due to their health hazards to human cardiovascular disease. Heavy metals, including lead, cadmium, mercury, arsenic, and chromium, are found in various sources such as air, water, soil, food, and industrial products. Recent research strongly suggests a connection between cardiovascular disease and exposure to toxic heavy metals. Epidemiological, basic, and clinical studies have revealed that heavy metals can promote the production of...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Ziwei Pan Tingyu Gong Ping Liang Source Type: research

Perfluoroalkyl/Polyfluoroalkyl Substances: Links to Cardiovascular Disease Risk
Circ Res. 2024 Apr 26;134(9):1136-1159. doi: 10.1161/CIRCRESAHA.124.323697. Epub 2024 Apr 25.ABSTRACTConservative estimates by the World Health Organization suggest that at least a quarter of global cardiovascular diseases are attributable to environmental exposures. Associations between air pollution and cardiovascular risk have garnered the most headlines and are strong, but less attention has been paid to other omnipresent toxicants in our ecosystem. Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are man-made chemicals that are extensively used in industrial and consumer products worldwide and in aqueous film-for...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Jennifer J Schlezinger Noyan Gokce Source Type: research

Introduction to the Compendium On Environmental Impacts on Cardiovascular Health and Biology
Circ Res. 2024 Apr 26;134(9):1047. doi: 10.1161/CIRCRESAHA.124.324664. Epub 2024 Apr 25.NO ABSTRACTPMID:38662857 | DOI:10.1161/CIRCRESAHA.124.324664 (Source: Circulation Research)
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Naomi M Hamburg Kathryn J Moore Source Type: research

Association of Ecoregion Distribution of Greenness With Cardiovascular Mortality: A Longitudinal Ecological Study in the United States
Circ Res. 2024 Apr 26;134(9):1221-1223. doi: 10.1161/CIRCRESAHA.124.324427. Epub 2024 Apr 25.NO ABSTRACTPMID:38662855 | DOI:10.1161/CIRCRESAHA.124.324427 (Source: Circulation Research)
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Daniel W Riggs Natalie C DuPre Peter James Shesh N Rai Ray Yeager Clara G Sears Francine Laden Aruni Bhatnagar Source Type: research

Enhancing long-term survival prediction with two short-term events: Landmarking with a flexible varying coefficient model
In this study, we aim to improve the prediction of long-term survival probability by incorporating two short-term events using a flexible varying coefficient landmark model. Our objective is to predict the long-term survival among patients who survived up to a pre-specified landmark time since the initial admission. Inverse probability weighting estimation equations are formed based on the information of the short-term outcomes before the landmark time. The kernel smoothing method with the use of cross-validation for bandwidth selection is employed to estimate the time-varying coefficients. The predictive performance of th...
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Wen Li Qian Wang Jing Ning Jing Zhang Zhouxuan Li Sean I Savitz Amirali Tahanan Mohammad H Rahbar Source Type: research

Primary Sjogren's syndrome independently promotes premature subclinical atherosclerosis
CONCLUSIONS: Subclinical atherosclerosis occurs earlier and more severely in patients with pSS. The difference in cIMT between pSS and controls seems mainly driven by patients with OI, suggesting that this subgroup is particularly at risk. OxLDL ab might protect against atherosclerotic progression in patients with pSS. CVR stratification and preventive medications such as Hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors should be discussed and further longitudinal studies are needed.PMID:38663882 | DOI:10.1136/rmdopen-2023-003559 (Source: Atherosclerosis)
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Nadine Zehrfeld Malin Abelmann Sabrina Benz Clara Luisa Zippel Sonja Beider Emelie Kramer Tabea Seeliger Georgios Sogkas Vega G ödecke Gerrit Ahrenstorf Franz Paul Armbruster Thomas Skripuletz Torsten Witte Anselm Arthur Derda Kristina Sonnenschein Diana Source Type: research

Perfluoroalkyl/Polyfluoroalkyl Substances: Links to Cardiovascular Disease Risk
Circ Res. 2024 Apr 26;134(9):1136-1159. doi: 10.1161/CIRCRESAHA.124.323697. Epub 2024 Apr 25.ABSTRACTConservative estimates by the World Health Organization suggest that at least a quarter of global cardiovascular diseases are attributable to environmental exposures. Associations between air pollution and cardiovascular risk have garnered the most headlines and are strong, but less attention has been paid to other omnipresent toxicants in our ecosystem. Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are man-made chemicals that are extensively used in industrial and consumer products worldwide and in aqueous film-for...
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Jennifer J Schlezinger Noyan Gokce Source Type: research

Heavy Metal Exposure and Cardiovascular Disease
Circ Res. 2024 Apr 26;134(9):1160-1178. doi: 10.1161/CIRCRESAHA.123.323617. Epub 2024 Apr 25.ABSTRACTHeavy metals are harmful environmental pollutants that have attracted widespread attention due to their health hazards to human cardiovascular disease. Heavy metals, including lead, cadmium, mercury, arsenic, and chromium, are found in various sources such as air, water, soil, food, and industrial products. Recent research strongly suggests a connection between cardiovascular disease and exposure to toxic heavy metals. Epidemiological, basic, and clinical studies have revealed that heavy metals can promote the production of...
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Ziwei Pan Tingyu Gong Ping Liang Source Type: research

Subclinical Atherosclerosis to Guide Treatment in Dyslipidemia and Diabetes Mellitus
Curr Atheroscler Rep. 2024 Apr 25. doi: 10.1007/s11883-024-01202-w. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Dyslipidemia and type 2 diabetes mellitus are two common conditions that are associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD). In this review, we aimed to provide an in-depth and contemporary review of non-invasive approaches to assess subclinical atherosclerotic burden, predict cardiovascular risk, and guide appropriate treatment strategies. We focused this paper on two main imaging modalities: coronary artery calcium (CAC) score and computed tomography coronary angiograph...
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Reed Mszar Miriam E Katz Gowtham R Grandhi Albert D Osei Antonio Gallo Michael J Blaha Source Type: research