Analysis of differential metabolites in serum metabolomics of patients with aortic dissection
Pathogenesis and diagnostic biomarkers of aortic dissection (AD) can be categorized through the analysis of differential metabolites in serum. Analysis of differential metabolites in serum provides new methods... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 25, 2024 Category: Cardiology Authors: Yun Gong, Tangzhiming Li, Qiyun Liu, Xiaoyu Wang, Zixian Deng, Lixin Cheng, Biao Yu and Huadong Liu Tags: Research Source Type: research
Effects on physical activity, physical fitness and well-being in a 36-months randomized controlled study, comparing a multimodal hospital-based intervention programme for primary cardiovascular prevention with usual care
Cardiovascular disease is a major cause of mortality and morbidity worldwide, and primary prevention efforts are poorly developed in people at high cardiovascular risk. On this background, we performed the Hje... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 25, 2024 Category: Cardiology Authors: Hilde Bergum, Jostein Grimsmo, Sigmund Alfred Anderssen and Tor Ole Klemsdal Tags: Research Source Type: research
The foundation for investigating factor XI as a target for inhibition in human cardiovascular disease
AbstractAnticoagulant therapy is a mainstay in the management of patients with cardiovascular disease and related conditions characterized by a heightened risk for thrombosis. Acute coronary syndrome, chronic coronary syndrome, ischemic stroke, and atrial fibrillation are the most common. In addition to their proclivity for thrombosis, each of these four conditions is also characterized by local and systemic inflammation, endothelial/endocardial injury and dysfunction, oxidative stress, impaired tissue-level reparative capabilities, and immune dysregulation that plays a critical role in linking molecular events, environmen...
Source: Journal of Thrombosis and Thrombolysis - April 25, 2024 Category: Hematology Source Type: research
Exploring the relationship between pericoronary inflammation and microvascular function
Inflammation is a key driver of atherosclerotic plaque development and progression. Pericoronary adipose tissue (PCAT) attenuation index is a novel non-invasive marker obtained from computed tomography coronary angiography (CTCA) that is a surrogate for the degree of coronary inflammation.1 Atheroma contain by-products of lipid metabolism, especially oxidised LDL and reactive oxygen species that are released into the downstream coronary circulation with consequent potential to affect endothelial function and microcirculatory tone. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - April 25, 2024 Category: Radiology Authors: Harsh V. Thakkar, Jasmine Chan, Andrea Comella, Abdul R. Ihdayhid, Michael Michail, Nitesh Nerlekar, Adam J. Brown Tags: Correspondence Source Type: research
Prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam
ConclusionsThe prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam was 42.1% for an AHI of ≥ 15 events/h. (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 25, 2024 Category: Respiratory Medicine Source Type: research
Cardiovascular risk in ADT recipients: does the type of ADT matter?
Prostate Cancer and Prostatic Diseases, Published online: 25 April 2024; doi:10.1038/s41391-024-00832-0Cardiovascular risk in ADT recipients: does the type of ADT matter? (Source: Prostate Cancer and Prostatic Diseases)
Source: Prostate Cancer and Prostatic Diseases - April 25, 2024 Category: Urology & Nephrology Authors: Jehonathan H. Pinthus Wilhelmina C. M. Duivenvoorden Source Type: research
Post-translational modifications in kidney diseases and associated cardiovascular risk
Nature Reviews Nephrology, Published online: 25 April 2024; doi:10.1038/s41581-024-00837-xChronic kidney disease (CKD) is associated with several alterations in protein post-translational modifications. Here, the authors examine the evidence of these alterations, their links with CKD progression and cardiovascular risk in patients with CKD, and their potential clinical applications. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - April 25, 2024 Category: Urology & Nephrology Authors: Heidi Noels Vera Jankowski Stefan J. Schunk Raymond Vanholder Sahir Kalim Joachim Jankowski Source Type: research
Postoperative serum mir-28-5p level has predictive value for the prognosis after endovascular abdominal aortic aneurysm repair
We explored the clinical significance of miR-28-5p pre- and post-endovascular abdominal aortic aneurysm repair (EVAR) in abdominal aortic aneurysm (AAA) patients. (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 25, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Senyan Wu, Guobing Cheng, Wei Lu and Youyao Xu Tags: Research Source Type: research
Anesthetic management during laparoscopic liver resection in a patient with Fontan physiology and high central venous pressure
The Fontan procedure was developed in 1971 for the surgical palliation of patients with single ventricle physiology [1]. In patients with Fontan physiology, pulmonary perfusion depends on pulmonary vascular resistance and systemic venous pressure. Long-term survival after the Fontan procedure has improved [2]. However, chronically high venous pressure may cause liver congestion and lead to the development of hepatocellular carcinoma (HCC) [3]. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 25, 2024 Category: Anesthesiology Authors: Kousuke Kikuchi, Akira Iura, Naohiro Hara, Takeshi Iritakenishi, Daisuke Hiramatsu, Yuji Fujino Tags: Case Report Source Type: research
“Con: Is Minimal Invasive Extracorporeal Circulation Superior to Conventional Cardiopulmonary Bypass in Cardiac Surgery?”
While individualized treatment is one of the pillars of the evolving practice towards a more physiological perfusion approach, further than “the elections of the artists”, decision-making algorithms considering different strategies to reduce blood product requirements (BPR) during Cardiopulmonary Bypass (CPB), should be implemented by Cardiac Surgery teams, considering the adequacy to circumstances and the cost-benefit balance. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 25, 2024 Category: Anesthesiology Authors: Morillo J. Blanco, M Vives Tags: Pro and Con Source Type: research
Del nido cardioplegia in adults: a retrospective observational study in comparison to modified St. Thomas cardioplegia in cardiac surgery
St. Thomas cardioplegia is commonly administered to adults, yet repeated dosing at brief intervals is required. Del Nido ’s cardioplegic solution provides a prolonged duration of safe myocardial arrest, yet it ... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 25, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Sanjeeve Kumar Garg, Rajinder Singh Rawat, Dina Afifi Saad and Ihab Omar Tags: Research Source Type: research
METTL14-mediated N6-methyladenosine modification induces the ferroptosis of hypoxia/reoxygenation-induced cardiomyocytes
Hypoxia/reoxygenation (H/R) induces cardiomyocyte ferroptosis, a core remodeling event in myocardial ischemia/reperfusion injury. Methyltransferase-like 14 (METTL14) emerges as a writer of N6-methyladenosine (... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 25, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Chunyu Zhao and Jianing Li Tags: Research Source Type: research
Circulating progenitor cells and coronary collaterals in chronic Total occlusion
The role of circulating progenitor cells (CPC) in collateral formation that occurs in the presence of chronic total occlusions (CTO) of a coronary artery is not well established. In stable patients with a CTO, we investigated whether CPC levels are associated with (a) collateral development and (b) ischemic burden, as measured by circulating high sensitivity troponin-I (hsTn-I) levels. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 25, 2024 Category: Cardiology Authors: Daniel A. Gold, Pratik B. Sandesara, Bryan Kindya, Matthew E. Gold, Vardhmaan Jain, Nishant Vatsa, Shivang R. Desai, Adithya Yadalam, Alexander Razavi, Malika Elhage Hassan, Yi-An Ko, Chang Liu, Ayman Alkhoder, Alireza Rahbar, Mohammad S. Hossain, Edmund Source Type: research
Targeting immune cell recruitment in atherosclerosis
Nature Reviews Cardiology, Published online: 25 April 2024; doi:10.1038/s41569-024-01023-zIn this Review, the authors discuss the receptors, ligands and interactors that regulate immune cell recruitment in atherosclerosis, describe mechanisms that promote the resolution of inflammation in atherosclerotic lesions, and highlight potential strategies to target these pathways for the treatment of atherosclerotic cardiovascular disease. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - April 25, 2024 Category: Cardiology Authors: Yvonne D öring Emiel P. C. van der Vorst Christian Weber Source Type: research
The coronary sinus reducer improves angina symptoms in patients with stable CAD
Nature Reviews Cardiology, Published online: 25 April 2024; doi:10.1038/s41569-024-01033-xFindings from the ORBITA-COSMIC trial show that treatment of patients with stable coronary artery disease using a coronary sinus reducer improves angina symptoms but does not increase transmural myocardial perfusion. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - April 25, 2024 Category: Cardiology Authors: Karina Huynh Source Type: research
