Analysis of the 2023 European Multidisciplinary (ESC/ESICM/EACTS) Consensus Statement on the Management of Short-term Mechanical Circulatory Support of Cardiogenic Shock in Adults in the Intensive Cardiac Care Unit
Despite medical advancements, mortality in cardiogenic shock (CS) remains unacceptably high.1-3 The decreased cardiac output resulting in impaired oxygen delivery, characteristic of CS, triggers a dismal cascade culminating in tissue hypoperfusion, multiorgan failure, and death if not intervened upon early.4 Given the scarcity of interventions to alleviate this harmful progression, there has been a notable increase in utilization of percutaneous mechanical circulatory support devices aimed at restoring blood flow and oxygen delivery, despite limited evidence supporting their efficacy. (Source: Journal of Cardiothoracic and...
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Katrina Joy Augustin, Patrick M. Wieruszewski, Lewis McLean, Eric Leiendecker, Harish Ramakrishna Tags: Expert Review Source Type: research

Towards better anticoagulation monitoring for extracorporeal membrane oxygenation – Taking C-reactive Protein Out of the Equation?
C-reactive protein (CPR) is an acute phase reactant protein, primarily synthesized in the liver.1 It belongs to the Pentraxin family of the innate immune system, serving as a pattern recognition molecule for phosphorylcholine residues abundant in bacterial cell membranes. It also binds to damaged cells and altered self-antigens, making it a valuable marker for inflammation, particularly in conditions such as rheumatoid arthritis and certain types of vasculitis. CRP exhibits a notable affinity for oxidized phosphatidylcholine (lysophosphatidylcholine) expressed on apoptotic cells and in oxidized low-density lipoproteins (LD...
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Kenichi A. Tanaka, Kenneth E. Steward, Michael A. Mazzeffi Tags: Editorial Source Type: research

Effect of low-dose ketamine infusion on opioid consumption in children undergoing open cardiac surgery: a randomized controlled double-blind study
Open cardiac surgery in the pediatric population is associated with severe metabolic and neurohumeral responses that adversely affect the cardiorespiratory system, resulting in a high risk of morbidity and mortality. 1,2,3 Up to 75% of patients who underwent cardiac surgery experienced moderate to severe postoperative pain that arises mainly from sternotomy incision and to a lesser extent from the sites of mediastinal drainage tubes. 4 (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Mahmoud Abdelfattah, Ibrahim Abdelbaser, Kareem Ali Awad, Ahmed Magdy Atallah, Mohamed Sanad, Mohamed Sayedalahl Tags: Original Article Source Type: research

The Ketogenic Diet and Pediatric Cardiac Surgery A Case Report and Narrative Review
Epilepsy affects approximately 470,000 children in the US(1) and up to 40% of these patients do not achieve adequate control with antiepileptic drugs (AED) alone.(2, 3) The addition of a ketogenic diet, which switches the energy source in the brain from glucose to ketones, can decrease the seizures frequency in some cases by up to 50%.(4, 5) A special high fat and low carbohydrate diet is used to achieve ketosis and metabolic changes otherwise seen during starvation. Unlike fatty acids, ketones can cross the blood brain barrier and are an important alternative energy source for the brain. (Source: Journal of Cardiothoracic...
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Mckenna Longacre, Laurence Ohia, Sharon Boyle, Kevin Conner, Aditya Kaza, Annette Schure Tags: Case Report Source Type: research

Implementation of Routine In Situ Simulation in Residency Curriculum Targeting Competency in Technical and Decision-Making Skills
To describe the development and implementation of a comprehensive in situ simulation-based curriculum for anesthesia residents. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Nadav Levy, Shirin Saeed, Peva F Gbagornah, David Benavides Zora, Dario Winterton, Cullen D Jackson, Aidan Sharkey, Lior Levy, Sara Neves, Daniel P Walsh, Robina Matyal Tags: Original Article Source Type: research

Regarding the predictor of perioperative stroke/TIA in carotid endarterectomy patients
We read Monaco's recent study1 with great interest. The authors assessed the relationship between thrombin receptor activator peptide 6 (TRAP), adenosine-5 ′-diphosphate (ADP), and arachidonic acid (ASPI) tests measured using multiple electrode aggregometry and the rate of stroke/transient ischemic attack (TIA) in patients undergoing carotid endarterectomy (CEA). They used a logistic LASSO regression model to identify factors independently associated with stroke/TIA. They concluded that an ADP>72 U and the need for a shunt during CEA were the only 2 variables independently associated with perioperative stroke/TIA. (Sourc...
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Ying Zhang, Weiwei Chen Tags: Letter to the Editor Source Type: research

Advancing perioperative medicine with continuous cardiac ultrasound monitoring: a call for multicenter-based effectiveness-implementation hybrid studies
Continuous echocardiography monitoring offers a non-invasive and convenient method for tracking changes in cardiac structure and function over time, enabling early detection of anomalies and intervention. In recent years, significant technological advancements have been made in noninvasive cardiac monitoring methods for perioperative medicine, particularly in acute care settings. While echocardiography has proven especially valuable in this context, existing clinical studies have limitations, including small sample sizes, single study centers, a lack of standardized protocols, and implementation challenges. (Source: Journa...
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Mingjing Chen, Ramzi G. Salloum, Haibo Song Tags: Letter to the Editor Source Type: research

Is supraclavicular subclavian venous catheterization superior to the infraclavicular approach? The devil is in the details.
We read with interest the recent work of Gong et al.1 The authors compared the ultrasound-guided supraclavicular and infraclavicular approaches for subclavian vein cannulation in children with congenital heart disease. Compared with the infraclavicular approach, supraclavicular cannulation of the subclavian vein had a higher success rate (90.6% vs. 71.4%), shorter time to access (median difference -4.2 seconds), and less frequent catheter malposition. The study's findings may be at least partially explained by the operators ’ lack of familiarity with the supraclavicular approach. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 24, 2024 Category: Anesthesiology Authors: Evangelia Samara, Mona Momeni, Petros G. Tzimas, Mohamed R. El Tahan Tags: Letter to Editor Source Type: research

Veno-venous extracorporeal membrane oxygenation for covid-19 in postpartum patients: 1-year outcome
During the pandemic, a significant number of patients with severe COVID-19 pneumonia required intensive care. Among these, peripartum women were particularly susceptible to severe respiratory symptoms. This complex pathophysiology involves mechanical and hormonal pathways, including the presence of lung restriction 1, modulation of the immune system by pregnancy 2, and increased oxygen demand 3. Additionally, a high level of vaccine hesitancy in this population meant that most pregnant women were not vaccinated during the COVID-19 pandemic 4. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 23, 2024 Category: Anesthesiology Authors: Alexandra P álfi, Éva Zöllei, Zoltán Varga, László B. Tomozi, Domonkos Schulcz, Gábor Bari, Ferenc Peták, Fruzsina Kun-Szabó, Kristóf Baráth, László Rudas, Ádám L. Balogh, Barna Babik Tags: Case Report Source Type: research

Effect of Urine Output on the Predictive Precision of NephroCheck in On-Pump Cardiac Surgery with Crystalloid Cardioplegia: Insights from the PrevAKI Study
Acute kidney injury (AKI) is the most common major complication after cardiac surgery.1 Unfortunately, neither interventions nor pharmaceutical agents have yet demonstrated an effect in treating AKI once it has occurred after cardiac surgery.2,3 (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 23, 2024 Category: Anesthesiology Authors: Fabrizio Monaco, Rosa Labanca, Stefano Fresilli, Gaia Barucco, Margherita Licheri, Giovanna Frau, Paul Osenberg, Alessandro Belletti Tags: Original Article Source Type: research

Effectiveness of adaptive support ventilation in facilitating weaning from mechanical ventilation in postoperative patients
This meta-analysis aims to evaluate the effectiveness of adaptive support ventilation (ASV) in facilitating postoperative weaning from mechanical ventilation in cardiac surgery patients. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 23, 2024 Category: Anesthesiology Authors: Yu-Chi Tsai, Hong-Jie Jhou, Chih-Wei Huang, Cho-Hao Lee, Po-Huang Chen, Sheng-Der Hsu Tags: Original Article Source Type: research

One-lung ventilation techniques to facilitate thoracoscopic surgery: time for some different studies?
To the Editor: (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 22, 2024 Category: Anesthesiology Authors: John Pfitzner Tags: Letter to the Editor Source Type: research

Continuous Right Ventricular Pressure Monitoring in Cardiac Surgery
Right ventricular (RV) dysfunction in cardiac surgery can lead to RV failure which is associated with increased morbidity and mortality. Abnormal RV function can be identified using RV pressure monitoring. The primary objective of the study is to determine the proportion of patients with abnormal RV early to end-diastole diastolic pressure gradient (RVDPG) and abnormal RV end-diastolic pressure (RVEDP) before initiation and after cardiopulmonary bypass (CPB) separation. Secondary objective is to evaluate if RVDPG before CPB initiation is associated with difficult and complex separation from CPB, RV dysfunction and failure ...
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 22, 2024 Category: Anesthesiology Authors: Andr é Denault, Etienne J. Couture, Tjorvi Perry, Elena Saade, Alexander Calderone, Yu Hao Zeng, Daniel Scherb, Kevin Moses, Cristhian Potes, Ali Hammoud, William Beaubien-Souligny, Mahsa Elmi-Sarabi, Lars Grønlykke, Yoan Lamarche, Jean-Sébastien Lebon Source Type: research

Locoregional versus General Anesthesia for Carotid Artery Stenting in the ِAmerican College of Surgeons National Surgical Quality Improvement Project
The current surgical management of high-grade carotid stenosis includes carotid endarterectomy (CEA) and carotid artery stenting (CAS). CAS may be done via a transfemoral percutaneous approach (tfCAS) or by transcervical carotid artery revascularization (TCAR) via open common carotid exposure. Less commonly, a transradial approach for CAS may also be employed. Concerns regarding periprocedural stroke due to arch instrumentation during tfCAS led to the development of TCAR, and early results for this procedure have been favorable with short-term outcomes similar to CEA 1, 2. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 20, 2024 Category: Anesthesiology Authors: Issam Koleilat, John Denesopolis, Michael Parides, Katherine P. MacCallum, Evan Lipsitz Source Type: research

Platelet-Rich Plasma Sequestration in Cardiac Surgery in a Jehovah's Witness
Jehovah's Witnesses (JW) refuse allogeneic blood transfusions due to their religious beliefs. This situation poses significant challenges in the context of cardiac surgery, given that bleeding-related complications may arise during and after the procedure.1 Platelet-rich plasma (PRP) sequestration in cardiac surgery has been previously described.2-4 The new-generation autotransfusion device XTRA (LivaNova, UK) processes fresh donor blood using the device's built-in ‘PLT sequestration program’. According to Seyfried, platelet recovery in the PRP ranged from 39%-64%. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 19, 2024 Category: Anesthesiology Authors: Tabesh Azami, Bastiaan M Gerritse, Rene Daane, Thierry V Scohy Tags: Case Report Source Type: research