Exploring the relationship between pericoronary inflammation and microvascular function

Inflammation is a key driver of atherosclerotic plaque development and progression. Pericoronary adipose tissue (PCAT) attenuation index is a novel non-invasive marker obtained from computed tomography coronary angiography (CTCA) that is a surrogate for the degree of coronary inflammation.1 Atheroma contain by-products of lipid metabolism, especially oxidised LDL and reactive oxygen species that are released into the downstream coronary circulation with consequent potential to affect endothelial function and microcirculatory tone.

Source: Journal of Cardiovascular Computed Tomography - April 25, 2024 Category: Radiology Authors: Harsh V. Thakkar, Jasmine Chan, Andrea Comella, Abdul R. Ihdayhid, Michael Michail, Nitesh Nerlekar, Adam J. Brown Tags: Correspondence Source Type: research