Progression of Whole-Heart Atherosclerosis by Coronary CT and Major Adverse Cardiovascular Events
The current study aimed to examine the independent prognostic value of whole-heart atherosclerosis progression by serial coronary computed tomography angiography (CCTA) for major adverse cardiovascular events (MACE). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - December 31, 2020 Category: Radiology Authors: Alexander R. van Rosendael, Fay Y. Lin, Inge J. van den Hoogen, Xiaoyue. Ma, Umberto. Gianni, Omar Al Hussein Alawamlh, Subhi J. Al'Aref, Jessica M. Pe ña, Daniele. Andreini, Matthew J. Budoff, Filippo. Cademartiri, Kavitha. Chinnaiyan, Jung Hyun. Choi, Tags: Research paper Source Type: research

Association of Neutrophil-to-Lymphocyte Ratio with Non-calcified Coronary Artery Burden in Psoriasis: Findings from an Observational Cohort Study
Inflammation in the form of elevated high-sensitivity c-reactive protein (hs-CRP) has been shown to be critical in the development of atherothrombosis. Psoriasis, a chronic inflammatory skin disease, is associated with high systemic-inflammation, elevated neutrophil-to-lymphocyte ratio (NLR) and accelerated non-calcified coronary artery burden (NCB) by coronary computed tomography angiography (CCTA). We hypothesized that NLR would associate with early, rupture-prone atherosclerosis assessed as NCB independent of hs-CRP. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - December 27, 2020 Category: Radiology Authors: Amit K. Dey, Heather L. Teague, Nicholas H. Adamstein, Justin A. Rodante, Martin P. Playford, Marcus Y. Chen, David A. Bluemke, Joel M. Gelfand, Paul M. Ridker, Nehal N. Mehta Tags: Research paper Source Type: research

Reproducibility of quantitative plaque measurement in advanced coronary artery disease
The ability to characterize and to quantify the extent of coronary artery disease has the potential to improve the prognostic capability of coronary computed tomography angiography. Although reproducible techniques have been described in those with mild coronary disease, this has yet to be assessed in patients with advanced disease. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - December 27, 2020 Category: Radiology Authors: Mohammed N. Meah, Trisha Singh, Michelle C. Williams, Marc R. Dweck, David E. Newby, Piotr Slomka, Philip D. Adamson, Alastair J. Moss, Damini Dey Tags: Research paper Source Type: research

Spectral Photon-Counting CT in Cardiovascular Imaging
Photon-counting CT is an emerging technology with the potential to substantially improve cardiovascular imaging. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - December 20, 2020 Category: Radiology Authors: Veit Sandfort, Mats Persson, Amir Pourmorteza, Peter B. No ël, Dominik Fleischmann, Martin J. Willemink Tags: Invited review Source Type: research

SCCT: a growing community
Over the past decade we witnessed the maturation of cardiac CT into an essential diagnostic test in the management of patients with cardiovascular disease. In various clinical contexts, care providers have recognized the value of noninvasive coronary imaging in the diagnostic work up of patients with suspected coronary artery disease, based on strong scientific evidence from around the world. In addition, novel minimally invasive interventions for structural heart disease rely on cardiac CT for selection of suitable candidates and the planning of procedures. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - December 15, 2020 Category: Radiology Authors: Koen Nieman Tags: SCCT President's Page Source Type: research

CT assessment of the left atrial appendage post-transcatheter occlusion – A systematic review and meta analysis.
Transesophageal echocardiography (TEE) is the standard imaging modality used to assess the left atrial appendage (LAA) after transcatheter device occlusion. Cardiac computed tomography angiography (CCTA) offers an alternative non-invasive modality in these patients. We aimed to conduct a comparison of the two modalities. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - December 15, 2020 Category: Radiology Authors: Sandeep Banga, Mohammed Osman, Partho P. Sengupta, Mina M. Benjamin, Sirish Shrestha, Abhiram Challa, Irfan Zeb, Madhavi Kadiyala, James Mills, Sudarshan Balla, Bryan Raybuck, Karthik Seetharam, Yasmin S. Hamirani Tags: Review article Source Type: research

Determination of optimal fluoroscopic angulations for aorto-coronary ostial interventions from coronary computed tomography angiography
An optimal aorto-coronary angiographic projection, characterized by an orthogonal visualization of the proximal coronary artery, is crucial for interventional success. We determined the distribution of optimal C-arm positions and assessed their feasibility by invasive coronary angiography. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - December 10, 2020 Category: Radiology Authors: Michaela M. Hell, Christian Schlundt, Daniel Bittner, Mohamed Marwan, Stephan Achenbach Tags: Research paper Source Type: research

Multiphase TAVR CT identifies unexpected sticky situation (Mechanical mitral valve leaflet dysfunction and Bicuspid Aortic Valve)
60-year-old female with history of 33mm ATS mechanical mitral valve replacement 16 years ago for rheumatic mitral valve disease and permanent Atrial Fibrillation (AF) presented with one-year history of worsening exertional dyspnoea as well as symptom of pre-syncope. She was on warfarin for AF as well as mechanical mitral valve replacement (MVR) with therapeutic anticoagulation in the recent time. Her transthoracic echocardiogram was technically difficult as MVR leaflet motion and aortic valve morphology was not well visualised because of artefact from mechanical mitral valve (Panel 1 A : 4chamber still echo image showing r...
Source: Journal of Cardiovascular Computed Tomography - December 7, 2020 Category: Radiology Authors: Arun Dahiya, John Coucher, Jit pratap, Chris Cole Tags: Case report Source Type: research

President ’s page
As we are moving into the New Year, we may slowly look forward to life as it was before. On so many levels, 2020 has been a challenging year for all of us, testing our strength, our patience and our resilience. Professional societies like the SCCT had to respond, realign objectives and modify expectations. Taking stock at the end of the year, I am proud of how we as a society have navigated these challenges. We converted our educational offerings to well-received online events, developed guidance documents including consensus documents on the use of cardiac CT during the pandemic, and continued our advocacy efforts. (Sourc...
Source: Journal of Cardiovascular Computed Tomography - December 1, 2020 Category: Radiology Authors: Koen Nieman Tags: SCCT President ’s Page Source Type: research

President ’s page.
As we are moving into the New Year, we may slowly look forward to life as it was before. On so many levels, 2020 has been a challenging year for all of us, testing our strength, our patience and our resilience. Professional societies like the SCCT had to respond, realign objectives and modify expectations. Taking stock at the end of the year, I am proud of how we as a society have navigated these challenges. We converted our educational offerings to well-received online events, developed guidance documents including consensus documents on the use of cardiac CT during the pandemic, and continued our advocacy efforts. (Sourc...
Source: Journal of Cardiovascular Computed Tomography - December 1, 2020 Category: Radiology Authors: Koen Nieman Tags: SCCT President's Page Source Type: research

Diagnostic Performance of Cardiac Computed Tomography versus Transesophageal Echocardiography in Infective Endocarditis: a Contemporary Comparative Meta-analysis
Data regarding the comparison of diagnostic accuracy of TEE and CCT for diagnosing IE are limited. The present meta-analysis compares the diagnostic performance of the two imaging modalities for a variety of complications of IE in the same patient populations. Our results show that both TEE and CCT have good diagnostic accuracy, with TEE showing superiority in detecting leaflet defects and CCT performing better in prosthetic valve endocarditis. CCT also showed a trend towards higher sensitivity than TEE for detection of periannular complications. These findings suggest that CCT is a useful adjunct to TEE for IE, whenever a...
Source: Journal of Cardiovascular Computed Tomography - November 30, 2020 Category: Radiology Authors: Vardhmaan Jain, Tom Kai Ming Wang, Agam Bansal, Medhat Farwati, Mohamed Gad, Bryce Montane, Simrat Kaur, Michael A. Bolen, Richard Grimm, Brian Griffin, Bo Xu Tags: Research paper Source Type: research

Training and Competency in Cardiovascular Computed Tomography: Collaborative Paradigm for the Rising Tide
The advent of 64-detector row cardiovascular computed tomography (CCT) in 2005 ushered in a new era in cardiovascular medicine. At the time, the ability of CCT to non-invasively perform coronary angiography represented the potential “holy grail” test as compared to an array of functional tests designed to infer coronary artery disease severity based on electrocardiographic or imaging surrogates. At the time of its introduction, which occurred during the peak of drug-eluting stent enthusiasm, the focus of coronary CT angiogr aphy (CCTA) in this pre-COURAGE (Clinical Outcomes Utilizing Revascularization and Aggre...
Source: Journal of Cardiovascular Computed Tomography - November 29, 2020 Category: Radiology Authors: Andrew D. Choi, Maros Ferencik, Jonathon Leipsic, Michelle C. Williams, Todd C. Villines Tags: Editor's Page Source Type: research

Anomalous left coronary artery from the pulmonary artery: an unusual cause of cardiac arrest
A 41 year old male presented following an out of hospital cardiac arrest whilst playing football. He received immediate bystander cardio-pulmonary resuscitation, was successfully defibrillated and transferred to a tertiary cardiology centre. He had previously undergone metallic mitral valve replacement at the age of 11. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 29, 2020 Category: Radiology Authors: Victoria M. Stoll, Helen Mathias, Alexander Zaphiriou, Lucy E. Hudsmith Tags: Case report Source Type: research

SCCT 2021 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the Society of Cardiovascular Computed Tomography
Cardiac computed tomography (CT) has changed rapidly since the last major guideline from SCCT (1). While there have been significant advances in technology, the most gratifying part has been the development of a robust evidence base for the use of cardiac CT in diagnoses of heart disease, prognostication and modulating therapy (both medical and interventional). Such a systematic development of knowledge base has not been the usual practice for any other imaging modality before widespread clinical acceptance in the past. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 19, 2020 Category: Radiology Authors: Jagat Narula, Y. Chandrashekhar, Amir Ahmadi, Suhny Abbara, Daniel S. Berman, Ron Blankstein, Jonathon Leipsic, David Newby, Edward D. Nicol, Koen Nieman, Leslee Shaw, Todd C. Villines, Michelle Williams, Harvey S. Hecht Tags: Guidelines Source Type: research

Coronary Sinus To Left Atrium Fistula On Computed Tomography Angiography: Differentiation From Unroofed Coronary Sinus With Literature Review
Atrial septal defect (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 13, 2020 Category: Radiology Authors: Rami M. Abazid, Ahmed Goha, Jonathan G. Romsa, James C. Warrington, Cigdem Akincioglu, Robert Z. Stodilka, Bob Kiaii, William C. Vezina Tags: Case report Source Type: research

Discrete subaortic stenosis characterized with ECG-gated cardiac CT: A case series
A 44 year-old female with a known history of discrete subaortic stenosis (DSAS) presented for routine surveillance transthoracic echocardiography (TTE). She denied symptoms. TTE demonstrated severe DSAS, with peak and mean gradients of 93 and 46  mm Hg, respectively. Also present were mild aortic regurgitation (AR) and mild left ventricular hypertrophy (LVH). She was referred for clinical evaluation. Her physical exam demonstrated a harsh 3/6 mid-systolic murmur radiating to the carotid arteries. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 12, 2020 Category: Radiology Authors: Andrew N. Cai, Matthew J. Budoff, Priya Pillutla Tags: Case report Source Type: research

Use of Cardiac CT Amidst the COVID-19 Pandemic and Beyond: North American Perspective
The COVID-19 pandemic has affected patient care deliver throughout the world, resulting in a greater emphasis on efficiently and safety. In this article, we discuss the experiences of several North American centers in utilizing cardiac CT during the pandemic. We also provide a case-based overview which highlights the advantages of cardiac CT in evaluating the following scenarios: (1) patients with possible myocardial injury versus myocardial infarction; (2) patients with acute chest pain ; (3) patients with stable chest pain; (4) patients with possible intracardiac thrombus; (5) patients with valvular heart disease. (Sourc...
Source: Journal of Cardiovascular Computed Tomography - November 12, 2020 Category: Radiology Authors: Vasvi Singh, Andrew D. Choi, Jonathon Leipsic, Ayaz Aghayev, James P. Earls, Philipp Blanke, Michael Steigner, Leslee J. Shaw Phd, Marcelo F. Di Carli, Todd C. Villines, Ron Blankstein Tags: Review article Source Type: research

Discrete subaortic stenosis characterization with ECG-gated cardiac CT: A case series
A 44 year-old female with a known history of discrete subaortic stenosis (DSAS) presented for routine surveillance transthoracic echocardiography (TTE). She denied symptoms. TTE demonstrated severe DSAS, with peak and mean gradients of 93 and 46 mm Hg, respectively. Also present were mild aortic regurgitation (AR) and mild left ventricular hypertrophy (LVH). She was referred for clinical evaluation. Her physical exam demonstrated a harsh 3/6 mid-systolic murmur radiating to the carotid arteries. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 12, 2020 Category: Radiology Authors: Andrew N. Cai, Matthew Budoff, Priya Pillutla Tags: Case report Source Type: research

Society of Cardiovascular Computed Tomography / North American Society of Cardiovascular Imaging – Expert Consensus Document on Coronary CT Imaging of Atherosclerotic Plaque
Coronary computed tomographic angiography (CCTA) provides a wealth of clinically meaningful information beyond anatomic stenosis alone, including the presence or absence of nonobstructive atherosclerosis and high-risk plaque features as precursors for incident coronary events. There is, however, no uniform agreement on how to identify and quantify these features or their use in evidence-based clinical decision-making. This statement from the Society of Cardiovascular Computed Tomography and North American Society of Cardiovascular Imaging addresses this gap and provides a comprehensive review of the available evidence on i...
Source: Journal of Cardiovascular Computed Tomography - November 9, 2020 Category: Radiology Authors: Leslee J. Shaw, Ron Blankstein, Jeroen J. Bax, Maros Ferencik, Marcio Sommer Bittencourt, James K. Min, Daniel S. Berman, Jonathon Leipsic, Todd C. Villines, Damini Dey, Subhi Al ’Aref, Michelle Williams, Fay Lin, Lohendran Baskaran, Harold Litt, Diana Tags: Guidelines Source Type: research

Are There Ethnic Differences in Coronary Volume and Myocardial Mass? If So, What Does It Mean?
Coronary CT angiography (CTA) has become an invaluable tool for the assessment of coronary artery disease (CAD). The first-line use of coronary CTA in patients without known CAD has been widely adapted in recent European guidelines, and hopefully soon in the United States.1,2 The ability of coronary CTA to diagnosed patients with subclinical CAD is a unique strength of CTA compared to other non-invasive tests and better identifies patients more likely to benefit from more aggressive preventive treatments. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 3, 2020 Category: Radiology Authors: Steve W. Leung Tags: Invited review Source Type: research

Table of contents-4C
(Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 1, 2020 Category: Radiology Source Type: research

Short Membranous Septum Length in Bicuspid Aortic Valve Stenosis Increases the Risk of Conduction Disturbances
This study sought to evaluate whether the incidence of permanent pacemaker implantation (PPMI) and left bundle branch block (LBBB) in patients with bicuspid aortic stenosis (AS) following transcatheter aortic valve replacement (TAVR) is related to an anatomical association between bicuspid AS and short membranous septal (MS) length. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 28, 2020 Category: Radiology Authors: Ashraf Hamdan, Mithal Nassar, Ehud Schwammental, Gidon Perlman, Ziad Arow, Jonathan Lessick, Arthur Kerner, Alon Barsheshet, Hana Vaknin Assa, Abid Assali, Yaron Aviv, Orly Goitein, Yafim Brodov, Pablo Codner, Katia Orvin, David Biton, Eyal Klein, Haim Da Tags: Research paper Source Type: research

Clinical Impact of Mitral Calcium Volume in Patients Undergoing Transcatheter Aortic Valve Implantation
Mitral annular calcification (MAC) has been associated with mitral valve (MV) disease and cardiovascular events in patients undergoing transcatheter aortic valve implantation (TAVI). We aimed to investigate the incidence and impact of mitral calcium volume (MCV) quantified by multidetector computed tomography (MDCT) on MV function and clinical outcomes after TAVI. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 21, 2020 Category: Radiology Authors: Taishi Okuno, Nicolas Brugger, Masahiko Asami, Dik Heg, George C.M. Siontis, Mirjam G. Winkel, Jonas Lanz, Christoph Gr äni, Adrian Huber, Stefan Stortecky, Isaac George, Susheel Kodali, Thomas Pilgrim, Stephan Windecker, Omar K. Khalique, Fabien Praz Tags: Research paper Source Type: research

Early Effects of Transcatheter Edge-to-Edge Leaflet Repair for Tricuspid Regurgitation: First-in-Human Experience with Computed Tomography
The feasibility of transcatheter tricuspid valve repair (TTVr) with the TriClip system (Abbott Structural, Menlo Park, CA) has been demonstrated with safe and effective tricuspid regurgitation (TR) reduction and improvement in quality of life (1). The TriClip device reduces TR via approximation of the tricuspid leaflet edges to enhance coaptation in a similar fashion of MitraClip device, but with a modified delivery system. Mitral annulus remodeling has been described after MitraClip treatment (2), but little is known about the TriClip effects on the geometry of the tricuspid annulus. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 8, 2020 Category: Radiology Authors: Bernardo B.C. Lopes, Paul Sorajja, Go Hashimoto, Miho Fukui, Yu Du, Aisha Ahmed, John Lesser, Jo ão L. Cavalcante Tags: Case report Source Type: research

Effectiveness of Point-of-Care Oral Ivabradine for Cardiac Computed Tomography
Coronary CT angiography (CCTA) is increasing seen as a first line investigation in patients with suspected coronary artery disease. Heart-rate control improves the image quality and diagnostic accuracy of CCTA. Typically, beta-blockers are administered to induce sinus bradycardia. Sinus bradycardia may also be induced by ivabradine. We hypothesized that in a real-world population ivabradine would be an effective alternative to metoprolol at heart rate lowering for CCTA. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 4, 2020 Category: Radiology Authors: Emel Celiker Guler, Yeung Yam, Kateleen Jia, Huda El Mais, Alomgir Hossain, Benjamin J.W. Chow, Gary R. Small Tags: Research paper Source Type: research

Does the ISCHEMIA Trial Provide the Appropriate Cohort to Compare Anatomical and Physiologic Testing?
Since the presentation and subsequent publication of the International Study Of Comparative Health Effectiveness With Medical And Invasive Approaches (ISCHEMIA) trial, multiple intense debates erupted in the medical press and on social media on the implications of these findings on clinical practice.1 This landmark randomized clinical trial attempted to investigate whether revascularization in addition to optimal medical therapy could lower events in patients with moderate to severe ischemia on physiologic imaging. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 30, 2020 Category: Radiology Authors: Mouaz H. Al-Mallah Tags: Invited review Source Type: research

Highlights of the 15th Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography
The 15th Society of Cardiovascular Computed Tomography (SCCT) annual scientific meeting (ASM) welcomed 770 digital attendees from 44 countries, over 2 days, with a program that included 30 sessions across three simultaneously streaming channels, 10 exhibitors and a diverse range of scientific abstracts. In addition, #SCCT2020 generated> 5,900 tweets from nearly 700 engaged social media participants resulting in an estimated 38 million digital impressions and becoming #1 trending medical meeting in social media in the world during the meeting time period. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 30, 2020 Category: Radiology Authors: Jonathan R. Weir-McCall, Kelley Branch, Maros Ferencik, Ron Blankstein, Andrew D. Choi, Brian B. Ghoshhajra, Kavitha Chinnaiyan, Purvi Parwani, Edward Nicol, Koen Nieman Tags: Opinion paper Source Type: research

Impact of Age on Coronary Artery Plaque Progression and Clinical Outcome: a PARADIGM substudy
The association of age with coronary plaque dynamics is not well characterized by coronary computed tomography angiography (CCTA). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 30, 2020 Category: Radiology Authors: Minkwan Kim, Seung-Pyo Lee, Soongu Kwak, Seokhun Yang, Yong-Jin Kim, Daniele Andreini, Mouaz H. Al-Mallah, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Hugo Marques, Pedro de Ara újo Gonçalves, Ilan Gottlieb Tags: Research paper Source Type: research

Pace of Guidance Publishing Accelerates in Cardiovascular CT
This summer the European Society of Cardiology (ESC) released the Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation guideline and gave a class I recommendation for coronary CT angiography (CCTA) as an alternative to invasive angiography to exclude ACS in patients with a low-to-intermediate likelihood of CAD and normal or inconclusive cardiac troponin and/or ECG. Furthermore, CCTA received a class I indication to assess CAD in patients with no recurrence of chest pain, normal ECG findings, and normal levels of cardiac troponin, but still with a suspected ACS, before deciding on invasive...
Source: Journal of Cardiovascular Computed Tomography - September 29, 2020 Category: Radiology Authors: Koen Nieman Tags: SCCT President's Page Source Type: research

The clinical utility of FFRCT stratified by age
CT coronary angiography (CTA) with Fractional Flow Reserve as determined by CT (FFRCT) is a safe alternative to invasive coronary angiography. A negative FFRCT has been shown to have low cardiac event rates compared to those with a positive FFRCT. However, the clinical utility of FFRCT according to age is not known. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 21, 2020 Category: Radiology Authors: Malcom Anastasius, Paul Maggiore, Alex Huang, Phillip Blanke, Manesh R. Patel, Bjarne Linde N ørgaard, Timothy A. Fairbairn, Koen Nieman, Takashi Akasaka, Daniel S. Berman, Gilbert L. Raff, Lynne M. Hurwitz Koweek, Gianluca Pontone, Tomohiro Kawasaki, Ni Tags: Research paper Source Type: research

Prognostic Value of Coronary Computed Tomography Angiography in Patients with Prior Percutaneous Coronary Intervention
501 PCI patients who underwent CCTA were followed for a mean of 59.5 months. 52 patients (10.4%) experienced MACE. CAD severity was a predictor of MACE with 0, 1, 2, and 3 vessel disease having annual rates of 1.3%, 2.2%, 2.2%, and 5.3%, respectively. In PCI patients, CAD severity as measured with CCTA has independent and incremental prognostic value. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 17, 2020 Category: Radiology Authors: Alomgir Hossain, Gary Small, Andrew M. Crean, Riley Jones, Yeung Yam, Helen Bishop, Benjamin J.W. Chow Tags: Research paper Source Type: research

Sex- and age-specific differences in the long-term prognostic value of morphological plaque features detected by coronary computed tomography angiography
While sex- and age-specific differences in coronary plaque features detected by coronary computed tomography angiography (CCTA) are known, insufficient information is available about the long-term prognostic value. 1,615 patients were examined by CCTA and coronary plaque features were assessed. A combined endpoint of cardiac death or nonfatal myocardial infarction was defined at a mean follow-up of 10.5 years. CCTA shows excellent long-term prognostic value irrespective of sex and age and independent from the higher prevalence of atherosclerotic plaques in men and patients older than 65 years. Although similarly prevalent ...
Source: Journal of Cardiovascular Computed Tomography - September 17, 2020 Category: Radiology Authors: Martyna Faber, Albrecht Will, Eva Hendrich, Stefan Martinoff, Martin Hadamitzky Tags: Research paper Source Type: research

Ethnic Differences in Coronary Anatomy, Left Ventricular Mass and CT-Derived Fractional Flow Reserve
This study compared ethnic differences in CT-assessed left-ventricular (LV) mass, coronary anatomy and non-invasive fractional-flow-reserve (FFRCT). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 17, 2020 Category: Radiology Authors: Abdul Rahman Ihdayhid, Udit Thakur, Grace Yap, Markus Goeller, Nitesh Nerlekar, Daniel Adams, Mourushi Isa, Mitwa Joshi, James Cameron, Sujith Seneviratne, Damini Dey, Stephan Achenbach, Jonathan Leipsic, Brian S. Ko Tags: Research paper Source Type: research

Feasibility of Coronary CT Angiography for Guidance of CABG
To assess the clinical safety and effectiveness of coronary revascularization in patients who underwent coronary artery bypass grafting (CABG) based exclusively on coronary computed tomography angiography (CCTA) results. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 16, 2020 Category: Radiology Authors: Andriy Nykonenko, Gudrun Feuchtner, Olexandr Nykonenko, Karina Chmul, Andrii Makarenkov, Darya Naumova, Vyacheslav Osaulenko, Orest Chevtchik Tags: Technical report Source Type: research

Syndromic association of aortopulmonary window in an adult: Hitherto unreported occurrence deciphered using cardiovascular CT
A 27-year-old male, a known case of Axenfeld-Reiger syndrome with congenital glaucoma, was being evaluated for ophthalmic surgery. For the past 6 months, he complained of dyspnea on exertion and palpitations. Prior to this, there was no history of any cardiac symptoms. Echocardiography revealed severe pulmonary artery hypertension with right ventricle hypertrophy and normal biventricular function. Cardiac CT angiography revealed presence of defect in aortopulmonary septum, approximately 2 cm above the sinotubular junction, suggestive of aortopulmonary window (APW). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 15, 2020 Category: Radiology Authors: Rishabh Khurana, Arun Sharma, Gautam Sharma, Chandrashekhara SH Tags: Case report Source Type: research

Assessment of Aortic Bioprosthetic Valve Fracture by Computed Tomography Angiography
A 71-year-old Jehovah ’s witness woman with a past medical history significant for diabetes mellitus, hypertension, breast cancer, aortic stenosis, and coronary artery disease underwent three-vessel coronary artery bypass graft (CABG) and surgical aortic valve replacement (SAVR) with a 19 mm Sorin Mitroflow (Sorin Grou p, CO, USA) (True internal diameter 15.4 mm). Severe patient prosthesis mismatch (PPM) (EOAi: 0.30 cm2/m2) was diagnosed shortly after surgery with post-operative mean gradients of 40 mmHg by echocardiography. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 15, 2020 Category: Radiology Authors: Go Hashimoto, Jo ão L. Cavalcante, Michael R. Mooney, Marcus R. Burns, Anene C. Ukaigwe, Santiago Garcia Tags: Case report Source Type: research

Reduction in Radiation Exposure using a Focused Low-Voltage scan before Coronary CT Angiography
The integration of cardiac computed tomography (CCT) as a noninvasive imaging modality within clinical care has provided a unique platform for the assessment of anatomy and physiology in patients at risk or suspected of having cardiovascular disease. This has been propelled by developments in hardware and software with gantry rotation speeds fast enough to produce diagnostic images of the heart and coronary circulation. As an example of the initial application of CCT, the quantitative assessment of coronary artery calcification (CAC), through the well-validated Agatston score, has become a cornerstone in guiding clinician ...
Source: Journal of Cardiovascular Computed Tomography - September 8, 2020 Category: Radiology Authors: Subhi J. Al ’Aref, Andrew J. Einstein Tags: Invited review Source Type: research

Features of Carcinoid Heart Disease Identified by Cardiac Computed Tomography
Carcinoid heart disease (HD) is a rare form of valvular heart disease, the features of which have not been fully described by cardiac computed tomography (CT). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - September 4, 2020 Category: Radiology Authors: Joseph Davar, Olga Lazoura, Martyn E. Caplin, Christos Toumpanakis Tags: Research paper Source Type: research

Role of Computed Tomography in COVID-19
Coronavirus disease 2019 (COVID-19) has become a rapid worldwide pandemic. While COVID-19 primarily manifests as an interstitial pneumonia and severe acute respiratory distress syndrome, severe involvement of other organs has been documented. In this article, we will review the role of non-contrast chest computed tomography in the diagnosis, follow-up and prognosis of patients affected by COVID-19 pneumonia with a detailed description of the imaging findings that may be encountered. Given that patients with COVID-19 may also suffer from coagulopathy, we will discuss the role of CT pulmonary angiography in the detection of ...
Source: Journal of Cardiovascular Computed Tomography - September 2, 2020 Category: Radiology Authors: Gianluca Pontone, Stefano Scafuri, Maria Elisabetta Mancini, Cecilia Agalbato, Marco Guglielmo, Andrea Baggiano, Giuseppe Muscogiuri, Laura Fusini, Daniele Andreini, Saima Mushtaq, Edoardo Conte, Andrea Annoni, Alberto Formenti, Antonio Giulio Gennari, An Tags: Invited review Source Type: research

Table of contents-4C
(Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 31, 2020 Category: Radiology Source Type: research

Importance of measurement site on assessment of lesion-specific ischemia and diagnostic performance by coronary computed tomography Angiography-Derived Fractional Flow Reserve
Values of fractional flow reserve (FFRCT) by coronary computed tomography angiography (CTA) decline from the ostium to the terminal vessel, irrespective of stenosis severity. The purpose of this study is to determine if the site of measurement of FFRCT impacts assessment of ischemia and its diagnostic performance relative to invasive FFR (FFRINV). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 28, 2020 Category: Radiology Authors: Elvis Cami, Travis Tagami, Gilbert Raff, Michael J. Gallagher, Austin Fan, Adam Hafeez, Stacy J. Willner, Priscilla Sigua Arce, Julie George, Abhay Bilolikar, Kavitha Chinnaiyan, Robert D. Safian Tags: Research paper Source Type: research

Cardiac Computed Tomography Improves the Identification of Cardiomechanical Complications among Patients with Suspected Left Ventricular Assist Device Malfunction
Left ventricular assist devices (LVAD) are increasingly used for durable mechanical circulatory support in advanced heart failure. While LVAD therapy provides substantial improvement in mortality and quality of life, long-term therapy confers increased risk for device complications. We evaluated if cardiac computed tomography (CCT) improves the detection of cardiomechanical complications among patients with LVAD and suspected device malfunction. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 26, 2020 Category: Radiology Authors: Priyesh A. Patel, Cynthia L. Green, Yuliya Lokhnygina, Jared Christensen, Carmelo A. Milano, Joseph G. Rogers, Chetan B. Patel, Lynne M. Koweek, Melissa A. Daubert Tags: Research paper Source Type: research

ISCHEMIA TRIAL – Failed intervention or failed stratification?
Treatment of stable ischemic heart disease remains controversial due to lack of proper measures to identify the vulnerable patient who will suffer acute coronary events. Imaging modalities can identify rupture-prone coronary plaques but studies have found that most plaque ruptures without causing clinical events (1). High risk plaques identified by CT Angiogram (CTA) was found to be predictive of acute coronary events (ACS) in a large cohort study but the extent of atherosclerotic burden was a confounder (2). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 25, 2020 Category: Radiology Authors: Matthew J. Budoff Tags: Editorial commentary Source Type: research

Focused, Low Tube Potential, Coronary Calcium Assessment Prior to Coronary CT Angiography: A Prospective, Randomized Clinical Trial
TOC Summary: To guide acquisition parameters, coronary calcium scanning is often performed prior to coronary CTA. A novel, modified calcium scan (with reduced radiation exposure) was compared to the standard Agatston method in a randomized clinical trial involving patients clinically referred for coronary CTA. A low-kVp, modified calcium scan focused on the proximal-to-mid coronary arteries similarly influenced final acquisition parameters of coronary CTA without negatively influencing overall image quality. Additionally, coronary CTA scan parameters are often modified following calcium assessment. (Source: Journal of Card...
Source: Journal of Cardiovascular Computed Tomography - August 21, 2020 Category: Radiology Authors: Hampton A. Crimm, Nicole M. Fergestrom, Cicely Dye, Cynthia Philip, Binh T. Nguyen, Todd C. Villines Tags: Research paper Source Type: research

Can we measure vulnerable plaques on coronary CT angiography with both precision and accuracy?
Non-invasive plaque detection using coronary CT angiography holds major potential for identifying patients at risk of subsequent coronary events. The rise in use of coronary CT angiography in both the United States and Europe is challenging the central dogma of the assessment of coronary artery disease which, to date, has focused on the identification of obstructive luminal stenoses and perturbations in myocardial blood flow. As illustrated in the SCOT-HEART trial, luminal stenosis is not the only imaging biomarker to determine the risk of future myocardial infarction [1]. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 18, 2020 Category: Radiology Authors: Alastair J. Moss, Michelle C. Williams Tags: Invited review Source Type: research

2020 SCCT Guideline for Training Cardiology and Radiology Trainees as Independent Practitioners (Level II) and Advanced Practitioners (Level III) in Cardiovascular Computed Tomography: A Statement from the Society of Cardiovascular Computed Tomography
Cardiovascular computed tomography (CCT) is a well-validated non-invasive imaging tool with an ever-expanding array of applications beyond the assessment of coronary artery disease. These include the evaluation of structural heart diseases, congenital heart diseases, peri-procedural electrophysiology applications, and the functional evaluation of ischemia. This breadth requires a robust and diverse training curriculum to ensure graduates of CCT training programs meet minimum competency standards for independent CCT interpretation. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 13, 2020 Category: Radiology Authors: Andrew D. Choi, Dustin M. Thomas, James Lee, Suhny Abbara, Ricardo C. Cury, Jonathon A. Leipsic, Christopher Maroules, Prashant Nagpal, Michael L. Steigner, Dee Dee Wang, Michelle C. Williams, Irfan Zeb, Todd C. Villines, Ron Blankstein Tags: Guideline Source Type: research

2020 Guideline for Training Cardiology and Radiology Trainees as Independent Practitioners (Level II) and Advanced Practitioners (Level III) in Cardiovascular Computed Tomography: A Statement from the Society of Cardiovascular Computed Tomography (SCCT)
Cardiovascular computed tomography (CCT) is a well-validated non-invasive imaging tool with an ever-expanding array of applications beyond the assessment of coronary artery disease. These include the evaluation of structural heart diseases, congenital heart diseases, peri-procedural electrophysiology applications, and the functional evaluation of ischemia(1). This breadth requires a robust and diverse training curriculum to ensure graduates of CCT training programs meet minimum competency standards for independent CCT interpretation. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 13, 2020 Category: Radiology Authors: Andrew D. Choi, Dustin M. Thomas, James Lee, Suhny Abbara, Ricardo Cury, Jonathon A. Leipsic, Christopher Maroules, Prashant Nagpal, Michael L. Steigner, Dee Dee Wang, Michelle C. Williams, Irfan Zeb, Todd C. Villines, Ron Blankstein Source Type: research

Plaque Quantification on Coronary CTA: The March Towards Standardization
The ability of coronary CTA to accurately diagnose angiographically significant coronary artery disease (CAD) forms the foundation for its increasing clinical utilization. While stenosis severity is usually the most prognostically powerful and clinically useful measure of CAD when assessing patients with stable or acute coronary syndromes, multiple studies have demonstrated the added value of coronary plaque features, extent of plaque involvement (segment involvement) and volumetric plaque quantification using increasingly automated approaches. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 10, 2020 Category: Radiology Authors: Todd C. Villines Tags: Editor's Page Source Type: research

Predictive value of the coronary artery calcium score and advanced plaque characteristics: Post hoc analysis of the PREDICT registry
Whether coronary plaque characteristics assessed in coronary computed tomography angiography (CCTA) in association with the coronary artery calcium score (CACS) have predictive value for coronary events is unclear. We aimed to examine the predictive value of the CACS and plaque characteristics for the occurrence of coronary events. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 8, 2020 Category: Radiology Authors: Hideya Yamamoto, Yasuki Kihara, Shinichiro Fujimoto, Hiroyuki Daida, Kazuhiro Kobuke, Yoshitaka Iwanaga, Shunichi Miyazaki, Tomohiro Kawasaki, Takashi Fujii, Sachio Kuribayashi Tags: Research paper Source Type: research

Effect of vessel wall segmentation on volumetric and radiomic parameters of coronary plaques with adverse characteristics
Information on the reproducibility of quantitative coronary plaque features with regards to differences in segmentation are scarce. In 100 coronary plaques with adverse imaging characteristics, we found that expert readers have good reproducibility for total, noncalcified and calcified plaque volumes (ICC: 0.84, 0.83 and 0.96), however for low-attenuation noncalcified plaque reproducibility was fair (ICC: 0.65). Radiomic features had good reproducibility (ICC>0.80) in 88.6% of first-order, 62.0% of gray level co-occurrence matrix, 75.8% of gray level run length matrix and 19.8% of geometrical parameters. Differences in ...
Source: Journal of Cardiovascular Computed Tomography - August 8, 2020 Category: Radiology Authors: M árton Kolossváry, Natasa Jávorszky, Júlia Karády, Milán Vecsey-Nagy, Tamás Zoltán Dávid, Judit Simon, Bálint Szilveszter, Béla Merkely, Pál Maurovich-Horvat Tags: Research paper Source Type: research