Validation of a computational model aiming to optimize preprocedural planning in percutaneous left atrial appendage closure
Percutaneous left atrial appendage (LAA) closure can be optimised through diligent preprocedural planning. Cardiac computational tomography (CCT) is increasingly recognised as a valuable tool in this process. A CCT-based computational model (FEops HEARTguide ™, Belgium) has been developed to simulate the deployment of the two most commonly used LAA closure devices into patient-specific LAA anatomies. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 20, 2019 Category: Radiology Authors: Alessandra M. Bavo, Benjamin T. Wilkins, Philippe Garot, Sander De Bock, Jacqueline Saw, Lars S øndergaard, Ole De Backer, Francesco Iannaccone Tags: Research paper Source Type: research

The feasibility, findings and future of CT-FFR in the emergency ward
Over the past decade a series of randomized trials have established noninvasive coronary angiography by computed tomography (CT) as a safe and potentially cost-effective strategy in the work-up of patients with acute chest pain and low-intermediate risk of acute coronary syndrome presenting in the emergency department.1 –8 Coronary CT angiography (CCTA) accurately rules out coronary artery disease, thereby minimizing the likelihood an acute coronary syndrome and obviating the need for prolonged observation and repeated ECGs and biomarker sampling. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 19, 2019 Category: Radiology Authors: Koen Nieman Tags: Editorial Source Type: research

Left ventricular outflow tract calcium and TAVR —The tip of the iceberg?
Transcatheter aortic valve replacement (TAVR) has inexorably altered the way physicians are able to treat symptomatic severe aortic stenosis.1 Patients once deemed too high-risk for surgical valve replacement (SAVR) are now able to undergo a percutaneous procedure for aortic stenosis treatment. Through large-scale multi-center trials, TAVR has been shown to be safe across all risk profiles, including low risk, expanding TAVR as a viable option to SAVR.2,3 Refinements in pre-procedural planning, extensive experience in peri- and intra-procedural imaging, as well as continual valve design innovation have further improved cli...
Source: Journal of Cardiovascular Computed Tomography - August 19, 2019 Category: Radiology Authors: Jeong W. Choi, Subhi J. Al ’Aref, Lohendran Baskaran, Jonathon A. Leipsic Tags: Editorial Source Type: research

Left ventricular outflow tract obstruction by thickened anterior mitral valve leaflet in a patient with tetralogy of Fallot
A 17-month-old male child presented with cyanosis and failure to thrive. Transthoracic echocardiography suggested a diagnosis of tetralogy of Fallot (TOF). The mitral valve leaflets were thickened without any hemodynamic evidence of stenosis or regurgitation and a normal-sized left atrium (LA). Concentric left ventricular hypertrophy (LVH) was also noted. Patient was referred for a computed tomography angiography (CTA) for better characterization of the cardiac and extracardiac anomalies. The scan was performed on a SOMATOM FORCE (Siemens Healthcare, Forchheim, Germany) CT scanner which is a third-generation dual source CT...
Source: Journal of Cardiovascular Computed Tomography - August 10, 2019 Category: Radiology Authors: Mumun Sinha, Niraj Nirmal Pandey, Arun Sharma, Nitin Parashar, Rengarajan Rajagopal, Sanjeev Kumar Tags: Case report Source Type: research

A simple method to visualize the bicuspid aortic valve pathology by cardiac computed tomography
We describe a simple technique, based on three-dimensional curved multiplanar reconstruction images, to obtain a pathology-like visualization of the full line of insertion (Hinge) of the aortic valve leaflets and of the interleaflet triangles with cardiac CT. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 8, 2019 Category: Radiology Authors: Francesca Amoretti, Alfredo Giuseppe Cerillo, Massimiliano Mariani, Pierluigi Stefano Source Type: research

Differences in left ventricular measurements: Attenuation versus contour based methods
This study aims to determine differences in LV volume measurements using the 2 methods. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 7, 2019 Category: Radiology Authors: Yici Liu, Sophia Bourgeois, Yeung Yam, Gary R. Small, Benjamin J.W. Chow Tags: Research paper Source Type: research

Interpretability of coronary CT angiography performed with a novel whole-heart coverage high-definition CT scanner in 300 consecutive patients with coronary artery bypass grafts
Coronary CT angiography (CCTA) is an accurate non-invasive tool for the evaluation of coronary artery bypass graft (CABG). However, inability to sustain a long breath-hold, high heart rate (HR) and atrial fibrillation may affect image quality. Moreover, radiation exposure is still a matter of some concern. A scanner combining 0.23-mm spatial resolution, new iterative reconstruction and fast gantry rotation time has been recently introduced in the clinical field. The aims of our study were to evaluate interpretability, radiation exposure and diagnostic accuracy of CCTA performed with the latest generation of cardiac-CT scan...
Source: Journal of Cardiovascular Computed Tomography - August 7, 2019 Category: Radiology Authors: Saima Mushtaq, Edoardo Conte, Gianluca Pontone, Giulio Pompilio, Marco Guglielmo, Andrea Annoni, Andrea Baggiano, Alberto Formenti, Maria Elisabetta Mancini, Giuseppe Muscogiuri, Flavia Nicoli, Caterina Giannitto, Marco Magatelli, Alessandra Tanzilli, Eli Tags: Research paper Source Type: research

Left circumflex artery to left atrial fistula: A rare entity diagnosed on computed tomography angiography
A 60-year-old male, with a diagnosis of infrarenal abdominal aortic stenosis underwent coronary computed tomography angiography (CTA) as part of pre-surgical evaluation. Review of CTA images demonstrated an anomalous fistulous communication between a dilated and tortuous branch (*) of the ostioproximal left circumflex (LCx) artery and the left atrium (LA). The tortuous vessel was seen coursing anterior to the LA, ultimately draining into it via a single communication (thick black arrow) in the anterior atrial wall near the ostium of the right superior pulmonary vein (Fig. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 7, 2019 Category: Radiology Authors: Mumun Sinha, Niraj Nirmal Pandey, Arun Sharma Tags: Case report Source Type: research

Coronary venous anatomy and anomalies
Coronary venous anatomy can be divided into the greater cardiac venous system and the lesser cardiac venous system. With protocol optimization, including appropriate contrast bolus timing, coronary veins can be depicted with excellent detail on CT. Knowledge of variant coronary venous anatomy can sometimes play a role in pre-procedural planning. Analysis of the coronary venous anatomy on CT can detect coronary venous anomalies that cause right to left shunts with risk of stroke, left to right shunts, and arrhythmias. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 7, 2019 Category: Radiology Authors: Arlene Sirajuddin, Marcus Y. Chen, Charles S. White, Andrew E. Arai Tags: Review article Source Type: research

Remission of “mistletoe sign” after treatment
We described a 55-year-old man, in whom the first manifestation of retroperitoneal fibrosis (RPF) was only coronary arterial involvement, which had no periaortic or peri-iliac and urinary system retroperitoneum involvement in general and other systemic clinical manifestations. Coronary manifestation was called “mistletoe sign” on the images. Here, we report a case of IgG4-related RPF remission that was only coronary arterial involvement after treatment. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 7, 2019 Category: Radiology Authors: Xiao Xu, Wei Bai, Heng Ma, Peng Dong, Haizhu Xie, Yinghong Shi, Chunjuan Sun, Jun Yang Tags: Case report Source Type: research

Congenital absence of the left atrial appendage
A 42-year-old man with no prior history of cardiovascular disease underwent coronary computed tomography angiography (CCTA) for evaluation of chest pain and dyspnea. Electrocardiography showed sinus bradycardia without any ischemic changes. CCTA demonstrated non-obstructive coronary artery disease. Assessment of cardiac structure in multiple imaging planes revealed agenesis of the left atrial appendage (LAA) (Fig. 2a –g). In comparison, CCTA in an age- and sex-matched patient shows normal cardiac anatomy (Fig. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - August 6, 2019 Category: Radiology Authors: Raymond A. Pashun, Michael P. Gannon, Chad Tomassetti, Navid Rahmani, Shahryar G. Saba Tags: Case report Source Type: research

Standardized reporting systems for computed tomography coronary angiography and calcium scoring: A real-world validation of CAD-RADS and CAC-DRS in patients with stable chest pain
To assess the prognostic implications of standardized reporting systems for coronary computed tomography angiography (CCTA) and coronary artery calcium scores (CACS) in patients with stable chest pain. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 26, 2019 Category: Radiology Authors: Michelle C. Williams, Alastair Moss, Marc Dweck, Amanda Hunter, Tania Pawade, Philp Adamson, Anoop.S.V. Shah, Shirjel Alam, Christopher D. Maroules, Edwin JR. van Beek, Ricardo Cury, Edward D. Nicol, David E. Newby, Giles Roditi Tags: Research paper Source Type: research

Effect of a calcium deblooming algorithm on accuracy of coronary computed tomography angiography
Coronary calcification deblooming using a prototype post-processing algorithm is feasible and significantly reduces calcium blooming with an improvement of the specificity of the CTA exam. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 25, 2019 Category: Radiology Authors: Jonathan R. Weir-McCall, Rui Wang, Jaydeep Halankar, Jiang Hsieh, Cameron J. Hague, Samuel Rosenblatt, Zhanming Fan, Stephanie Sellers, Darra T. Murphy, Philipp Blanke, Lei Xu, Jonathon A. Leipsic Source Type: research

Assessing the value of coronary artery computed tomography as the first-line anatomical test for stable patients with indications for invasive angiography due to suspected coronary artery disease. Economic outcomes of the CAT-CAD randomized trial
Clinical and safety outcomes of the strategy employing coronary computed tomography angiography (CCTA) as the first-choice imaging test in this population have been recently shown in the published CAT-CAD randomized, prospective, single-center study. Based on prospectively collected data we aimed to evaluate economic outcomes and cost-effectiveness of such innovative approach. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 25, 2019 Category: Radiology Authors: Piotr Nikodem Rudzinski, Mariusz Kruk, Cezary Kepka, U. Joseph Schoepf, Katharina Otani, Mariusz D ębski, Zofia Dzielinska, Jerzy Pregowski, Adam Witkowski, Witold Ruzyllo, Marcin Demkow Tags: Research paper Source Type: research

The clinical utility of hybrid imaging for the identification of vulnerable plaque and vulnerable patients
Despite decades of research and major innovations in technology, cardiovascular disease remains the leading cause of death globally. Our understanding of major cardiovascular events and their prevention is centred around the atherosclerotic plaque and the processes that ultimately lead to acute plaque rupture. Recent advances in hybrid imaging technology allow the combination of high spatial resolution and anatomical detail with molecular assessments of disease activity. This provides the ability to identify vulnerable plaque characteristics and differentiate active and quiescent disease, with the potential to improve pati...
Source: Journal of Cardiovascular Computed Tomography - July 17, 2019 Category: Radiology Authors: Rong Bing, Roel S. Driessen, Paul Knaapen, Marc R. Dweck Source Type: research

Should CT replace IVUS for evaluation of CAD in large-scale clinical trials: Effects of medical therapy on atherosclerotic plaque
Clinical trials assessing the effect of medical therapies on atherosclerotic plaques have hitherto employed invasive imaging techniques such as intravascular ultrasound (IVUS). This has limited the study population to high-risk patients in whom invasive coronary angiography is indicated; moreover, IVUS typically is performed utilizing a target lesion-based analysis. Recently, comprehensive quantitative analysis of all atherosclerotic plaques in the complete coronary artery network has become possible through the use of coronary computed tomography angiography (CCTA). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 10, 2019 Category: Radiology Authors: Sang-Eun Lee, Todd C. Villines, Hyuk-Jae Chang Tags: Invited review Source Type: research

Impact of severe left ventricular outflow tract calcification on device failure and short-term mortality in patients undergoing TAVI
To investigate the impact of left ventricular outflow tract (LVOT) calcification on the incidence of device failure and mortality in patients undergoing transcatheter aortic valve implantation (TAVI). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 9, 2019 Category: Radiology Authors: David Jochheim, Simon Deseive, Sarah Gschwendtner, Bernhard Bischoff, Sarah Jochheim, Sebastian Hausleiter, Magda Zadrozny, Moritz Baquet, Christian Tesche, Steffen Massberg, Julinda Mehilli, J örg Hausleiter Tags: Research paper Source Type: research

Comparative analysis of calcification parameters with Agatston Score approximations for ex vivo atherosclerotic lesions
The Agatston score is the gold standard of atherosclerotic calcium quantification. However, the Agatston score cannot identify vulnerable lesions. Recent investigations suggest that microcalcifications and a high number of ‘spotty’ calcified particles destabilise atherosclerotic plaques while high-density macrocalcifications protect against plaque rupture. However, it is not clear whether the Agatston score can distinguish between these atherosclerotic calcification phenotypes. Our results indicate that the Agatst on score correlates extremely well with calcified volume fractions but not with calcified particle...
Source: Journal of Cardiovascular Computed Tomography - July 9, 2019 Category: Radiology Authors: Rachel M. Cahalane, Stephen P. Broderick, Eamon G. Kavanagh, Michael A. Moloney, Rosaire Mongrain, Helen Purtill, Michael T. Walsh, Julie M. O'Brien Tags: Research paper Source Type: research

Total anomalous pulmonary venous connection with dual drainage: A rare configuration
A 7-year-old child with central cyanosis and failure to thrive underwent transthoracic echocardiography. The openings of the pulmonary veins into the left atrium (LA) could not be demonstrated suggesting a possible diagnosis of total anomalous pulmonary venous connection (TAPVC). The coronary sinus was also dilated indicating a cardiac or mixed variant of TAPVC. A cardiac computed tomography angiography (CTA) was advised to delineate the pulmonary venous anatomy. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 6, 2019 Category: Radiology Authors: Mumun Sinha, Niraj Nirmal Pandey, Arun Sharma Tags: Case report Source Type: research

Occlusion of the left main coronary artery ostium by aortic valve cusp fusion in an adult
A 46-year-old female was admitted to hospital because of dyspnea and chest pain for 2 months with no apparent symptoms in the past years. She had no family history of sudden death or cardiac disorder. ECG showed a paroxysmal atrial fibrillation. Coronary CT was performed, revealing normal right coronary artery and pouch-like filling in the small left coronary aortic sinus that seemed to be covered by the thickened rudimentary left coronary cusp (Fig. A,B,C). Transcatheter coronary angiography showed occlusion of the left main coronary artery ostium and was supplied by a major collateral artery from right coronary artery (F...
Source: Journal of Cardiovascular Computed Tomography - July 5, 2019 Category: Radiology Authors: Ziqing Xiong, Yunfei Ling, Qi An Tags: Case report Source Type: research

Quadricuspid aortic valve: 3D-visualization by computed tomography
A 53 year-old-male with arterial hypertension, positive family history of premature coronary artery disease and dyslipidemia, was referred to cardiac computed tomography angiography (CTA). There was previous echocardiogram suspicion of quadricuspid aortic valve (QAV). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 5, 2019 Category: Radiology Authors: Gudrun M. Feuchtner Tags: Case report Source Type: research

Is waist-to-height ratio better than body mass index as a predictive indicator of coronary atherosclerosis disease? A cohort study
Being overweight and obese are strongly associated with cardiovascular disease.1 Several different anthropometrical measurements are used in the clinical setting to predict disease risk in relation to overweight and obesity. Body mass index (BMI) is well known and frequently used, both in clinical practice and in the health and fitness industry.2 However, BMI is a measure of general adiposity which does not distinguish between central and general obesity. Prospective epidemiological studies have revealed that central obesity was more relevant to CAD risk compared to general obesity. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2019 Category: Radiology Authors: Zhi-hui Hou, Bin Lu, Zhen-nan Li, Yun-qiang An, Yang Gao, Wei-hua Yin, Matthew J. Budoff Tags: Research paper Source Type: research

Low dose contrast CT for transcatheter aortic valve replacement assessment: Results from the prospective SPECTACULAR study (spectral CT assessment prior to TAVR)
Computed tomographic angiography (CTA) based planning for transcatheter aortic valve replacement (TAVR) is essential for reduction of periprocedural complications. Spectral CT based imaging provides several advantages, including better contrast/signal to noise ratio and increased soft tissue contrast, permitting better delineation of contrast filled structures at lower doses of iodinated contrast media. The aim of this prospective study was to assess the initial feasibility of a low dose iodinated contrast protocol, utilizing monoenergetic 40  keV reconstruction, using a dual-layer CT scanner (DLCT) for CTA in patients u...
Source: Journal of Cardiovascular Computed Tomography - June 26, 2019 Category: Radiology Authors: Armando Ugo Cavallo, Andrew J. Patterson, Rahul Thomas, Mohamad Amer Alaiti, Guilherme F. Attizani, Kai Laukamp, Nils Grosse Hokamp, Hiram Bezerra, Robert Gilkeson, Sanjay Rajagopalan Tags: Research paper Source Type: research

Long-term health outcomes and cost-effectiveness of coronary CT angiography in patients with suspicion for acute coronary syndrome
Randomized trials have shown favorable clinical outcomes for coronary CT angiography (CTA) in patients with suspected acute coronary syndrome (ACS). Our goal was to estimate the cost-effectiveness of coronary CTA as compared to alternative management strategies for ACP patients over lifetime. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 25, 2019 Category: Radiology Authors: Alexander Goehler, Thomas Mayrhofer, Amit Pursnani, Maros Ferencik, Heidi S. Lumish, Cordula Barth, Julia Karady, Benjamin Chow, Quynh A. Truong, James E. Udelson, Jerome L. Fleg, John T. Nagurney, G. Scott Gazelle, Udo Hoffmann Source Type: research

The association of coronary lumen volume to left ventricle mass ratio with myocardial blood flow and fractional flow reserve
A diminished coronary lumen volume to left ventricle mass ratio (V/M) derived from coronary computed tomography angiography (CCTA) has been proposed as factor contributing to impaired myocardial blood flow (MBF) even in the absence of obstructive disease on invasive coronary angiography (ICA). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 24, 2019 Category: Radiology Authors: P.A. van Diemen, S.P. Schumacher, M.J. Bom, R.S. Driessen, H. Everaars, W.J. Stuijfzand, P.G. Raijmakers, P.M. van de Ven, J.K. Min, J.A. Leipsic, J. Knuuti, P.R. Boellaard, C.A. Taylor, A.C. van Rossum, I. Danad, P. Knaapen Tags: Research paper Source Type: research

‘The garland vein’- Retrotracheoesophageal brachiocephalic vein in tetralogy of Fallot: A rare anomalous course diagnosed on dual source CT
A 3month old child presented with recurrent cyanotic spells and feed intolerance. Echocardiography revealed tetralogy of Fallot (TOF). Preoperative computed tomography angiography (CTA), done on a 192  × 2 slice dual source CT scanner (Siemens Somatom Definition Force, Germany) revealed TOF with confluent good sized pulmonary arteries. Incidentally, the left brachiocephalic vein(left BCV)(Black stars in Fig. 1) was seen traversing downwards adjacent to the left subclavian artery, then coursi ng rightwards behind the trachea, proximal descending aorta and the esophagus and subsequently joining the right brachiocep...
Source: Journal of Cardiovascular Computed Tomography - June 17, 2019 Category: Radiology Authors: Vineeta Ojha, Arun Sharma, Kartik P. Ganga, Sanjeev Kumar Tags: Case report Source Type: research

The role of coronary CT angiography for acute chest pain in the era of high-sensitivity troponins
CCTA has become a valuable diagnostic tool in the emergency department for the triage of patients with acute chest pain. However, this role may change with the introduction of high-sensitivity troponins. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 15, 2019 Category: Radiology Authors: Shengwen Yang, Lakshman Manjunath, Martin J. Willemink, Koen Nieman Tags: Invited review Source Type: research

The role of coronary CT angiography in the era of high-sensitivity troponins
CCTA has become a valuable diagnostic tool in the emergency department for the triage of patients with acute chest pain. However, this role may change with the introduction of high-sensitivity troponins. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 15, 2019 Category: Radiology Authors: Shengwen Yang, Lakshman Manjunath, Martin J. Willemink, Koen Nieman Tags: Invited review Source Type: research

How accurate is atherosclerosis imaging by coronary computed tomography angiography?
Invasive coronary plaque imaging such as intravascular ultrasound and optical coherence tomography has been widely used to observe culprit or non-culprit coronary atherosclerosis, as well as optimize stent sizing, apposition and deployment. Coronary computed tomographic angiography (CTA) is non-invasively available to assess coronary artery disease (CAD) and has become an appropriate strategy to evaluate patients with suspected CAD. Given recent technologies, semi-automated plaque software is available to identify coronary plaque stenosis, volume and characteristics and potentially allows to be used for the assessment of m...
Source: Journal of Cardiovascular Computed Tomography - June 14, 2019 Category: Radiology Authors: Rine Nakanishi, Sadako Motoyama, Jonathon Leipsic, Matthew J. Budoff Tags: Invited review Source Type: research

The role of computed tomography myocardial perfusion imaging in clinical practice
Computed tomography coronary angiography (CTCA) is a widely accepted non-invasive technique for the accurate detection of coronary artery disease (CAD), but comes with a notable limitation stemming from its limited capacity to define the physiologic significance of a given lesion This hampered ability for functional assessment of coronary stenosis may lead to additional testing in an effort to delineate whether ischemia is truly present. An important technique that can overcome this pitfall of CTCA has emerged in the form of stress CT myocardial perfusion (CTP) imaging, which provides the functional assessment necessary, t...
Source: Journal of Cardiovascular Computed Tomography - June 13, 2019 Category: Radiology Authors: Amita Singh, Victor Mor-Avi, Amit R. Patel Tags: Review article Source Type: research

“What is the clinical role of non-invasive atherosclerosis imaging?”
Non-invasive atherosclerosis findings have been demonstrated to provide incremental diagnostic and predictive values for ischemia, acute coronary syndrome, and cardiovascular outcomes. The challenge is to translate research findings to a clinical role. Here, we review the current utility of atherosclerotic imaging and the incremental value of plaque imaging. We also evaluate future clinical and research implications for three patient populations: asymptomatic prevention, stable chest pain, and acute chest pain. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 12, 2019 Category: Radiology Authors: Fay Y. Lin, Todd C. Villines, Jagat Narula, Leslee J. Shaw Tags: Review article Source Type: research

Cardiovascular morbidity and mortality in patients with aortic valve calcification: A systematic review and meta-analysis
Aortic valve calcification (AVC) is an active process that involves inflammation, disorganization of matrix disposition, lipid accumulation and lamellar bone formation. AVC without hemodynamic changes has been associated with cardiovascular (CV) risk factors and increased risk of coronary and CV events. Nowadays, echocardiography is the standard imaging technique to evaluate aortic valve pathologies. However, cardiac computed tomography (CT) allows high accuracy and reproducible measurement of AVC, without exposing the patients to excessive radiation or contrast administration. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 11, 2019 Category: Radiology Authors: Matteo Nicola Dario Di Minno, Paolo Poggio, Edoardo Conte, Veronika Myasoedova, Paola Songia, Saima Mushtaq, Laura Cavallotti, Donato Moschetta, Alessandro Di Minno, Gaia Spadarella, Paolo Pizzicato, Gianluca Pontone, Mauro Pepi, Daniele Andreini Tags: Research paper Source Type: research

Impact of scan quality on the diagnostic performance of CCTA, SPECT, and PET for diagnosing myocardial ischemia defined by fractional flow reserve
Scan quality can have a significant effect on the diagnostic performance of non-invasive imaging techniques. However, the extent of its influence has scarcely been investigated in a head-to-head manner. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 11, 2019 Category: Radiology Authors: P.A. van Diemen, R.S. Driessen, W.J. Stuijfzand, P.G. Raijmakers, S.P. Schumacher, M.J. Bom, H. Everaars, J.K. Min, J.A. Leipsic, J. Knuuti, S.R. Underwood, P.M. van de Ven, A.C. van Rossum, I. Danad, P. Knaapen Tags: Research paper Source Type: research

Utilization of Coronary Computed Tomography Angiogram in evaluation of Left Ventricular thrombus
We present the following case to illustrate the role of Coronary Computed Tomography Angiogram (CCTA) in the evaluation of LV thrombus and its clinical significance in demonstrating fine surface details of the thrombus compared to Echo and CMR. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 10, 2019 Category: Radiology Authors: Manmohan Singh, Haider Aldiwani, Aiden Abidov Tags: Case report Source Type: research

Dynamic CT perfusion imaging: Few small steps toward the implementation into the real clinical world
Coronary CT angiography (CCTA) is a well-established, non-invasive imaging modality with excellent diagnostic accuracy in the identification of coronary atherosclerosis and detection of obstructive coronary artery disease (CAD) when compared to invasive coronary angiography (ICA) as reference standard.1 Moreover, several randomized controlled trials have shown how the use of CCTA in the management of symptomatic patients with stable CAD improves patients ’ outcomes, reducing the risk of long-term fatal and non-fatal myocardial infarction. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 10, 2019 Category: Radiology Authors: Alexia Rossi, Fabio Fazzari Tags: Editorial Source Type: research

Anomalous origin of left circumflex artery, myocardial bridges and myocardial ischemia
A 54-year-old woman with chest pain, without coronary risk factors and positive exercise stress test with changes in the ST segment with horizontal ST depression/T-wave symmetrical inversion 1,8 mm in leadsV3 to V6 (anterolateral leads) expression of ischemia in this territory and ST depression 1 mm DII, DIII and AVF with asymmetrical T-wave inversion (reciprocal changes), and chest paint. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 10, 2019 Category: Radiology Authors: Martin Ibarrola Tags: Case report Source Type: research

Exploring the intersection between genetic risk scores and coronary artery calcium – Mutually exclusive or complementary?
Accurate detection of increased cardiovascular disease (CVD) risk and timely prevention of CVD events remain two central needs in cardiovascular medicine. Over the last three decades, a number of clinical scores combining traditional risk factors have been developed, aimed at estimating a person's risk of CVD events and aiding the allocation of preventive pharmacotherapies.1 –3 However, in the present era of precision medicine, the performance of such scores has been proved to be far from optimal. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - June 3, 2019 Category: Radiology Authors: Miguel Cainzos-Achirica, Martin B ødtker Mortensen, Michael J. Blaha Tags: Editorial Source Type: research

Coronary artery calcium: A modern rubric for an established approach
The detection and quantification of subclinical calcified coronary atherosclerosis using low-dose cardiac computed tomography has been convincingly shown to be superior to traditional, population-derived risk factor-based approaches for the individualized assessment of cardiovascular risk. Coronary artery calcification, as a measure of overall atherosclerotic burden, serves as the phenotypic expression of the longitudinal amalgamation of the effects of acquired risk factors (and their treatment), genetic makeup and lifestyle exposures on atherosclerosis expression within the coronary arteries. (Source: Journal of Cardiovas...
Source: Journal of Cardiovascular Computed Tomography - May 25, 2019 Category: Radiology Authors: Subhi J. Al ’Aref, Andrew D. Choi, Todd C. Villines Tags: Editorial Source Type: research

Using CT left atrial appendage imaging to identify patients at higher risk of stroke
More than the last 5 –10 years, the left atrial appendage (LAA) has become an increasingly important anatomic site for cardiologists, especially in the prevention and management of stroke.1 Once felt to be a relatively benign entity, its role as a nidus for thrombus (especially in those with atrial fibrillation (AF)) has long been recognised, but with the advent of LAA exclusion devices, which may be internal (such as Watchman, Wavecrest and Amplatz devices), or external (such as the Lariat laso or Atriclip), the need to accurately assess the morphology of left atrial appendage has become increasingly important, both...
Source: Journal of Cardiovascular Computed Tomography - May 25, 2019 Category: Radiology Authors: E. Nicol Tags: Editorial Source Type: research

Exploring the intersection between genetic risk scores and coronary artery calcium – mutually exclusive or complementary?
coronary artery calcium (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 25, 2019 Category: Radiology Authors: Miguel Cainzos-Achirica, Martin B ødtker Mortensen, Michael J. Blaha Tags: Editorial Source Type: research

Non-invasive fractional flow reserve derived from coronary computed tomography angiography in patients with acute chest pain: Subgroup analysis of the ROMICAT II trial
Non-invasive fractional flow reserve (FFRCT) derived from coronary computed tomography angiography (CTA) permits hemodynamic evaluation of coronary stenosis and may improve efficiency of assessment in stable chest pain patients. We determined feasibility of FFRCT in the population of acute chest pain patients and assessed the relationship of FFRCT with outcomes of acute coronary syndrome (ACS) and revascularization and with plaque characteristics. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 15, 2019 Category: Radiology Authors: Maros Ferencik, Michael T. Lu, Thomas Mayrhofer, Stefan B. Puchner, Ting Liu, Pal Maurovich-Horvat, Khristine Ghemigian, Alexander Ivanov, Elizabeth Adami, John T. Nagurney, Pamela K. Woodard, Quynh A. Truong, James E. Udelson, Udo Hoffmann Tags: Research paper Source Type: research

An unusual left anterior descending artery myocardial bridging
A 43 year-old man was admitted in our intensive care unit in June 2016 for transient (10 min) acute chest pain highly suggestive of angina that appeared for an unusual intense effort. He has no personal history and none of traditional cardiovascular risk factors. Baseline electrocardiogram was normal and without repolarization abnormalities at rest. High sensitivity cardiac troponin was undetectable (inferior to 4 ng/mL). Trans-thoracic echocardiography found mild wall motion abnormalities of the apical and septo-apical segments but left ventricle ejection fraction remained subnormal at rest. (Source: Journal of Cardiovasc...
Source: Journal of Cardiovascular Computed Tomography - May 10, 2019 Category: Radiology Authors: Marjorie Richardson, Guillaume Schurtz, Valentina Silvestri, Gilles Lemesle Tags: Case report Source Type: research

Using a genetic risk score to calculate the optimal age for an individual to undergo coronary artery calcium screening
Genetic risk scores (GRSs) have been associated with CHD events and coronary artery calcium (CAC). We sought to evaluate the ability of a GRS to improve CAC as a screening test. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 9, 2019 Category: Radiology Authors: Lauren M. Severance, Francisco J. Contijoch, Hannah Carter, Chun C. Fan, Tyler M. Seibert, Anders M. Dale, Elliot R. McVeigh Tags: Research paper Source Type: research

Non-contrast cardiac CT-based quantitative evaluation of epicardial and intra-thoracic fat in healthy, recently menopausal women: Reproducibility data from the Kronos Early Estrogen Prevention Study
Cardiac fat is emerging as an important parameter for cardiovascular risk stratification. Accurate and reproducible volumetric measurements can facilitate in the serial assessment of cardiac fat by computed tomography (CT). We assessed the intra- and inter-observer variability of cardiac fat volumetric measurements using a semi-automated CT software. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 4, 2019 Category: Radiology Authors: Eranthi Jayawardena, Dong Li, Rine Nakanishi, Damini Dey, Christopher Dailing, Assad Qureshi, Brooke Dickens, Nicolai Hathiramani, Michael Kim, Ferdinand Flores, Ann E. Kearns, Li-Yung Lui, Dennis Black, Matthew J. Budoff Source Type: research

A case of prominent coronary plaque regression with statin therapy
Statin therapy has been shown to reduce coronary plaque volume in patients with coronary artery disease (CAD).1 In particular, strict control of LDL cholesterol (70 mg/dl) and also in Caucasians.2 (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 3, 2019 Category: Radiology Authors: Toru Awaya, Chiori Kodama, Masaya Yamamoto, Osamu Okazaki, Hisao Hara, Yukio Hiroi, Masao Moroi Tags: Case report Source Type: research

Free-breathing coronary CT angiography without heart-rate control: Feasibility in selected patients
Coronary CT Angiography (CTA) is increasingly used for noninvasive assessment of the coronary arteries. Recent advances in CT technology have greatly improved the image quality and accuracy of CTA. The standard recommended acquisition is to acquire the full CTA data in one breath hold, to avoid respiratory artifacts.1 As well, in terms of image quality, there is typically a tangible benefit with heart-rate control with beta-blockade before the scan.1 (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 3, 2019 Category: Radiology Authors: Damini Dey, Debiao Li Tags: Editorial Source Type: research

Moving beyond stenosis: Assessing ischemia based off plaque morphology and burden of disease on coronary CTA
The ideal noninvasive test would identify patients with coronary artery disease, characterize atherosclerotic plaque, and bridge the anatomic findings to functional significance of specific coronary lesions. Coronary computed tomographic angiography (CTA) has emerged as the gold standard noninvasive test for detecting coronary artery disease (CAD).1 –3 However, the identification of CAD alone is insufficient as the relationship between coronary stenosis and ischemia is complex and frequently discordant. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 3, 2019 Category: Radiology Authors: Mark G. Rabbat, John J. Lopez Tags: Editorial Source Type: research

Follow-up evaluation of magnesium bioresorbable stent with computed tomography
A 59-year-old male underwent coronary angiography due to non-ST elevation myocardial infarction, revealing a large plaque in the proximal left anterior descending artery causing severe stenosis. The lesion was prepared with predilatation and a 3.5  × 25 mm magnesium bioresorbable stent (BVS) was implanted (Fig. 1A), achieving a good final angiographic result after postdilatation with a 4 mm balloon (Fig. 1B). In the post-implantation intravascular ultrasound (IVUS) (Fig. 1C) a correct stent expansion and apposition were confirmed, allowi ng the detection of the proximal radiopaque marker (asterisk) and an eccentr...
Source: Journal of Cardiovascular Computed Tomography - May 3, 2019 Category: Radiology Authors: Eduardo Pozo Osinalde, Nieves Gonzalo, Pablo Salinas Tags: Case report Source Type: research

Index - JCCT 13/3S
(Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 1, 2019 Category: Radiology Source Type: research

Toc - jcct 13/3s
(Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - May 1, 2019 Category: Radiology Source Type: research