NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This NOFO will ut...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 2, 2024 Category: Research Source Type: funding

Immunobiology of Xenotransplantation (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-24-020 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to solicit applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), a multi-center program dedicated to resolving immunologic and physiologic barriers to safe and efficacious xenotransplantation using preclinical pig to nonhuman primate (NHP) or human decedent models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 1, 2024 Category: Research Source Type: funding

Immunobiology of Xenotransplantation (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-24-019 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to solicit applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), a multi-center program dedicated to resolving immunologic and physiologic barriers to safe and efficacious xenotransplantation using preclinical pig to nonhuman primate (NHP) or human decedent models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 1, 2024 Category: Research Source Type: funding

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be establis...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 1, 2024 Category: Research Source Type: funding

Model Continuums of Care Initiative (MCCI) to Advance Health Equity and End Health Disparities Among Women and Girls in Racial/Ethnic Minority and Other Underserved Communities (U34 Clinical Trials Required)
Funding Opportunity RFA-AA-24-006 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to support the planning phase of the Model Continuums of Care Initiative (MCCI) to Advance Health Equity and End Health Disparities Among Women and Girls in Racial/Ethnic Minority and Other Underserved Communities. MCCI is a multi-ICO dissemination and implementation science initiative to advance health equity and end health disparities in racial/ethnic minority women and girls of reproductive age. Specifically, the Model Continuums of Care Initiative will apply the latest dissemination and implementationscience app...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 6, 2024 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for Strategies for Preventing Cardiovascular Disease in Young Adults With High Lifetime Risk Using Surrogate Outcomes (Collaborative UG3/UH3 Clinical Trial Required)
Notice NOT-HL-24-003 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 14, 2024 Category: Research Source Type: funding

American Heart Association Rural Midwest Library Grant
Funding for rural libraries to leverage community assets to help address health challenges such as high blood pressure, nutrition insecurity, cardiovascular disease, and tobacco use. Geographic coverage: The American Health Association Midwest Region -- American Heart Association (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - February 1, 2024 Category: American Health Source Type: funding

NHLBI Announces Plan to Fund a Framingham Heart Study Exam for the Generation 2 and Omni 1 Cohorts
Notice NOT-HL-24-001 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 25, 2024 Category: Research Source Type: funding

New Year ’s Resolutions: NIH Funding Edition
New year, same list of resolutions as last year, right? Consider freshening them up with some suggestions from NIH staff. Start the year with a plan. If your NIH-funded research generates scientific data, make sure you develop a data management and sharing plan, specifically. Keep it simple. We’re taking this one to heart and working to simplify the peer review framework of research project grant applications and improve NRSA fellowship review in 2025. On  a related note, make it easy on reviewers  by making sure your application clearly responds to the review criteria found in the funding opportunity. ...
Source: NIH Extramural Nexus - January 12, 2024 Category: Research Authors: NIH Staff Tags: Top Stories Source Type: funding

Going For Gold and Beyond in the Rural Midwest: Grant for Health Care Organizations
Grants for rural healthcare organizations in the Midwest to lead evidence-based policy and practice changes in the areas of blood pressure, cholesterol, and type 2 diabetes. Geographic coverage: The Midwest region of the American Heart Association -- American Heart Association (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - December 16, 2023 Category: American Health Source Type: funding

Cardiovascular Repository Type 1 Diabetes (CARE-T1D) Consortium (U01 Clinical Trial Not Allowed).
Funding Opportunity RFA-DK-23-021 from the NIH Guide for Grants and Contracts. Cardiovascular complications are the leading cause of death for individuals with type 1 diabetes (T1D) and significantly shorten their lives. Cardiovascular disease (CVD) progression in people with T1D differs from that observed in people with type 2 diabetes (T2D) and residual increased risk of CVD remains after treatment of standard risk factors, such as hyperglycemia, hypertension, and hyperlipidemia. The NIH Cardiovascular Repository for T1D (CaRe-T1D) was initiated with the goal of establishing a biorepository of human CV tissue and a sc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 30, 2023 Category: Research Source Type: funding

Notice of NICHD Withdrawal from Participation in NOT-HL-23-117 "Notice of Special Interest (NOSI): Palliative Care in the Care Continuum among Persons with Serious Heart, Lung, Blood and Sleep (HLBS) Diseases and their Caregivers"
Notice NOT-HD-23-037 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 24, 2023 Category: Research Source Type: funding

NHLBI Program Project Applications (P01 Clinical Trials Optional)
Funding Opportunity PAR-24-065 from the NIH Guide for Grants and Contracts. The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 20, 2023 Category: Research Source Type: funding

NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
Funding Opportunity PAR-24-049 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this NOFO will support research projects that are designed to provide results that will be sufficient to inform the fu...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 3, 2023 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for Cardiovascular Repository Type 1 Diabetes (CARE-T1D) Consortium (U01 Clinical Trial Not Allowed).
Notice NOT-DK-24-001 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 20, 2023 Category: Research Source Type: funding