Implication of mixed sleep apnea events in adult patients with obstructive sleep apnea-hypopnea syndrome
ConclusionsOur study suggested that MSA was related to the stability of the ventilatory control in OSAHS patients. MSA events occur more frequently in patients with severe OSAHS, and male gender, obesity, daytime sleepiness, and elevated TG levels were risk factors for the mixed OSAHS. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 20, 2018 Category: Respiratory Medicine Source Type: research

Do you have restless leg syndrome? I understood from your eyes
ConclusionAccording to our results; most retinal layers are thinner in RLS patients, so it can be considered that OCT has a predictive value for progression of RLS. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 19, 2018 Category: Respiratory Medicine Source Type: research

Drug-induced sleep endoscopy (DISE) as a guide towards upper airway behavior and treatment outcome: the quest for a vigorous standardization of DISE.
Abstract PMID: 30338440 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 18, 2018 Category: Sleep Medicine Authors: Vanderveken OM Tags: Sleep Breath Source Type: research

Drug-induced sleep endoscopy: the effect of different passive maneuvers on the distribution of collapse patterns of the upper airway in obstructive sleep apnea patients.
CONCLUSIONS: This study gives new insights into the changes in distribution of collapse patterns when passive maneuvers are applied during DISE. Jaw thrust and lateral head rotation gave improvement of obstruction mostly in line with previous research. The CNCC and CCC groups responded similarly to application of a single maneuver, but there was a significant difference found when both maneuvers were combined. PMID: 30338441 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 18, 2018 Category: Sleep Medicine Authors: Beelen AMEH, Vonk PE, de Vries N Tags: Sleep Breath Source Type: research

Drug-induced sleep endoscopy: the effect of different passive maneuvers on the distribution of collapse patterns of the upper airway in obstructive sleep apnea patients
ConclusionsThis study gives new insights into the changes in distribution of collapse patterns when passive maneuvers are applied during DISE. Jaw thrust and lateral head rotation gave improvement of obstruction mostly in line with previous research. The CNCC and CCC groups responded similarly to application of a single maneuver, but there was a significant difference found when both maneuvers were combined. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 18, 2018 Category: Respiratory Medicine Source Type: research

Drug-induced sleep endoscopy (DISE) as a guide towards upper airway behavior and treatment outcome: the quest for a vigorous standardization of DISE
(Source: Sleep and Breathing)
Source: Sleep and Breathing - October 18, 2018 Category: Respiratory Medicine Source Type: research

Nutrigenetic genotyping study in relation to Sleep Apnea Clinical Score.
CONCLUSION: We failed to confirm previously reported associations between the majority of the studied polymorphisms and sleep apnea. Body weight seems to be an important cofounding factor that needs to be accounted for, when genetic association studies are performed for sleep apnea. PMID: 30334133 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 17, 2018 Category: Sleep Medicine Authors: Gkouskou K, Vlastos IM, Chaniotis D, Markaki A, Choulakis K, Prokopakis E Tags: Sleep Breath Source Type: research

Nutrigenetic genotyping study in relation to Sleep Apnea Clinical Score
ConclusionWe failed to confirm previously reported associations between the majority of the studied polymorphisms and sleep apnea. Body weight seems to be an important cofounding factor that needs to be accounted for, when genetic association studies are performed for sleep apnea. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 17, 2018 Category: Respiratory Medicine Source Type: research

Effects of 12  weeks of regular aerobic exercises on autonomic nervous system in obstructive sleep apnea syndrome patients.
Effects of 12 weeks of regular aerobic exercises on autonomic nervous system in obstructive sleep apnea syndrome patients. Sleep Breath. 2018 Oct 16;: Authors: Yang H, Liu Y, Zheng H, Liu G, Mei A Abstract INTRODUCTION: Regular exercise is confirmed as a lifestyle treatment option for all obstructive sleep apnea (OSA) patients. It has beneficial effects other than weight loss, although the mechanisms remain unclear. Autonomic function imbalance plays an important role in OSA, so that it is meaningful to observe the effect of exercise on autonomic function. METHODS: Seventy mild to moderate O...
Source: Sleep and Breathing - October 16, 2018 Category: Sleep Medicine Authors: Yang H, Liu Y, Zheng H, Liu G, Mei A Tags: Sleep Breath Source Type: research

Effects of 12  weeks of regular aerobic exercises on autonomic nervous system in obstructive sleep apnea syndrome patients
AbstractIntroductionRegular exercise is confirmed as a lifestyle treatment option for all obstructive sleep apnea (OSA) patients. It has beneficial effects other than weight loss, although the mechanisms remain unclear. Autonomic function imbalance plays an important role in OSA, so that it is meaningful to observe the effect of exercise on autonomic function.MethodsSeventy mild to moderate OSA patients were divided into two groups. The exercise group received a 12-week exercise program prescribed according to their first cardiopulmonary exercise tests, while the control group kept previous lifestyle. All patients underwen...
Source: Sleep and Breathing - October 16, 2018 Category: Respiratory Medicine Source Type: research

Effect of remifentanil during drug-induced sleep endoscopy in patients with obstructive sleep apnea.
CONCLUSIONS: Use of remifentanil during DISE reduces the target concentration of propofol required for patient sedation to perform DISE without respiratory depression. PMID: 30324545 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 15, 2018 Category: Sleep Medicine Authors: Kim Y, Park H, Shin J, Choi JH, Park SW, Kang HY Tags: Sleep Breath Source Type: research

Persistent sleep disordered breathing after adenoidectomy and/or tonsillectomy: a long-term survey in a tertiary pediatric hospital.
ynh N Abstract PURPOSE: To determine the long-term prevalence of persistent sleep disordered breathing (SDB) in children, after adenoidectomy, tonsillectomy or adenotonsillectomy, and to assess the relationship between baseline characteristics and persistent nocturnal symptoms. METHODS: The clinical charts of children operated for adenoidectomy and/or tonsillectomy in a tertiary hospital, between January 2000 and March 2016, were retrospectively reviewed. All patients who had signs of SDB prior to surgery received a six-question validated pediatric questionnaire, the Hierarchic Severity Clinical Scale (HSCS)....
Source: Sleep and Breathing - October 15, 2018 Category: Sleep Medicine Authors: Cohen-Levy J, Quintal MC, Abela A, Rompré P, Almeida FR, Huynh N Tags: Sleep Breath Source Type: research

Obstructive sleep apnea and self-reported functional impairment in revascularized patients with coronary artery disease in the RICCADSA trial.
This study evaluated the impact of OSA on sleep-related functional impairment in patients with CAD and compared the effect of 1-year continuous positive airway pressure (CPAP) use on change in impairment between those with and without excessive daytime sleepiness (EDS) and OSA. We hypothesized that sleep-related functional impairment is impacted by EDS independent of OSA in patients with CAD. METHODS: One hundred five CAD patients without OSA and 105 with moderate-to-severe OSA from the RICCADSA trial were matched on disease severity and included in the current substudy. Of those with OSA, 80 were allocated to CPAP. F...
Source: Sleep and Breathing - October 15, 2018 Category: Sleep Medicine Authors: Baniak LM, Chasens ER, Luyster FS, Strollo PJ, Thunström E, Peker Y Tags: Sleep Breath Source Type: research

4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated apoptosis and protects the hepatocytes from intermittent hypoxia-induced injury.
CONCLUSIONS: 4-PBA could protect liver cells by suppressing IH-induced apoptosis mediated by ERS, but not by reducing the UPR. PMID: 30324548 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 15, 2018 Category: Sleep Medicine Authors: Xin L, Fan W, Tingting D, Zuoming S, Qiang Z Tags: Sleep Breath Source Type: research

Obstructive sleep apnea and self-reported functional impairment in revascularized patients with coronary artery disease in the RICCADSA trial
This study evaluated the impact of OSA on sleep-related functional impairment in patients with CAD and compared the effect of 1-year continuous positive airway pressure (CPAP) use on change in impairment between those with and without excessive daytime sleepiness (EDS) and OSA. We hypothesized that sleep-related functional impairment is impacted by EDS independent of OSA in patients with CAD.MethodsOne hundred five CAD patients without OSA and 105 with moderate-to-severe OSA from the RICCADSA trial were matched on disease severity and included in the current substudy. Of those with OSA, 80 were allocated to CPAP. Functiona...
Source: Sleep and Breathing - October 15, 2018 Category: Respiratory Medicine Source Type: research

4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated apoptosis and protects the hepatocytes from intermittent hypoxia-induced injury
Conclusions4-PBA could protect liver cells by suppressing IH-induced apoptosis mediated by ERS, but not by reducing the UPR. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 15, 2018 Category: Respiratory Medicine Source Type: research

Persistent sleep disordered breathing after adenoidectomy and/or tonsillectomy: a long-term survey in a tertiary pediatric hospital
AbstractPurposeTo determine the long-term prevalence of persistent sleep disordered breathing (SDB) in children, after adenoidectomy, tonsillectomy or adenotonsillectomy, and to assess the relationship between baseline characteristics and persistent nocturnal symptoms.MethodsThe clinical charts of children operated for adenoidectomy and/or tonsillectomy in a tertiary hospital, between January 2000 and March 2016, were retrospectively reviewed. All patients who had signs of SDB prior to surgery received a six-question validated pediatric questionnaire, the Hierarchic Severity Clinical Scale (HSCS).ResultsA total of 4000 chi...
Source: Sleep and Breathing - October 15, 2018 Category: Respiratory Medicine Source Type: research

Effect of remifentanil during drug-induced sleep endoscopy in patients with obstructive sleep apnea
ConclusionsUse of remifentanil during DISE reduces the target concentration of propofol required for patient sedation to perform DISE without respiratory depression. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 15, 2018 Category: Respiratory Medicine Source Type: research

Alterations of the brain network in idiopathic rapid eye movement sleep behavior disorder: structural connectivity analysis.
CONCLUSIONS: This is the first study to report that structural volume and connectivity in patients with iRBD are significantly different from those in healthy controls. iRBD patients exhibited disrupted topological disorganization of the global brain network and hub reorganization. These alterations are implicated in the pathogenesis of iRBD. They might be potential biomarkers of iRBD. PMID: 30315394 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 12, 2018 Category: Sleep Medicine Authors: Park KM, Lee HJ, Lee BI, Kim SE Tags: Sleep Breath Source Type: research

Alterations of the brain network in idiopathic rapid eye movement sleep behavior disorder: structural connectivity analysis
ConclusionsThis is the first study to report that structural volume and connectivity in patients with iRBD are significantly different from those in healthy controls. iRBD patients exhibited disrupted topological disorganization of the global brain network and hub reorganization. These alterations are implicated in the pathogenesis of iRBD. They might be potential biomarkers of iRBD. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 12, 2018 Category: Respiratory Medicine Source Type: research

Addition of frontal EEG to adult home sleep apnea testing: does a more accurate determination of sleep time make a difference?
Abstract RATIONALE: Home sleep apnea testing (HSAT) typically does not include electroencephalogram (EEG) monitoring for sleep assessment. In patients with insomnia and low sleep efficiency, overestimation of the sleep period can result from absence of EEG, which will reduce sleep disordered breathing (SDB) indices and may lead to a false-negative result. OBJECTIVE: To validate a single channel frontal EEG for scoring sleep versus wake against full EEG during polysomnography, and then to examine the utility of adding this single channel EEG to standard HSAT to prevent false-negative results. METHODS: Epo...
Source: Sleep and Breathing - October 11, 2018 Category: Sleep Medicine Authors: Light MP, Casimire TN, Chua C, Koushyk V, Burschtin OE, Ayappa I, Rapoport DM Tags: Sleep Breath Source Type: research

Obesity modulates the association between sleep apnea treatment and CHI3L1 levels but not CHIT1 activity in moderate to severe OSA: an observational study.
Abstract PURPOSE: The inflammatory markers chitinase-3-like protein 1 (CHI3L1) and chitotriosidase (CHIT1) have both been associated with cardiovascular complications. The aim of this preliminary observational study was to assess the roles and interaction of obstructive sleep apnea (OSA) severity and body mass index (BMI) with plasma CHI3L1 levels and CHIT1 activity in patients with moderate to severe OSA. The second aim was to assess the roles and interaction of positive airway pressure (PAP) treatment and BMI on the expression of the same proteins. METHODS: The study included 97 OSA patients with an apnea-h...
Source: Sleep and Breathing - October 11, 2018 Category: Sleep Medicine Authors: Teitsdottir UD, Arnardottir ES, Bjornsdottir E, Gislason T, Petersen PH Tags: Sleep Breath Source Type: research

Obesity modulates the association between sleep apnea treatment and CHI3L1 levels but not CHIT1 activity in moderate to severe OSA: an observational study
AbstractPurposeThe inflammatory markers chitinase-3-like protein 1 (CHI3L1) and chitotriosidase (CHIT1) have both been associated with cardiovascular complications. The aim of this preliminary observational study was to assess the roles and interaction of obstructive sleep apnea (OSA) severity and body mass index (BMI) with plasma CHI3L1 levels and CHIT1 activity in patients with moderate to severe OSA. The second aim was to assess the roles and interaction of positive airway pressure (PAP) treatment and BMI on the expression of the same proteins.MethodsThe study included 97 OSA patients with an apnea –hypopnea index...
Source: Sleep and Breathing - October 11, 2018 Category: Respiratory Medicine Source Type: research

Addition of frontal EEG to adult home sleep apnea testing: does a more accurate determination of sleep time make a difference?
AbstractRationaleHome sleep apnea testing (HSAT) typically does not include electroencephalogram (EEG) monitoring for sleep assessment. In patients with insomnia and low sleep efficiency, overestimation of the sleep period can result from absence of EEG, which will reduce sleep disordered breathing (SDB) indices and may lead to a false-negative result.ObjectiveTo validate a single channel frontal EEG for scoring sleep versus wake against full EEG during polysomnography, and then to examine the utility of adding this single channel EEG to standard HSAT to prevent false-negative results.MethodsEpoch-by-epoch validation for s...
Source: Sleep and Breathing - October 11, 2018 Category: Respiratory Medicine Source Type: research

The use of mandibular advancement devices in obstructive sleep apnea: a proven and effective therapy.
PMID: 30302659 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 9, 2018 Category: Sleep Medicine Authors: Petrella C, Maluly M, Andersen ML, Tufik S Tags: Sleep Breath Source Type: research

The use of mandibular advancement devices in obstructive sleep apnea: a proven and effective therapy
(Source: Sleep and Breathing)
Source: Sleep and Breathing - October 9, 2018 Category: Respiratory Medicine Source Type: research

Laryngopharyngeal motor dysfunction and obstructive sleep apnea in Parkinson's disease.
CONCLUSION: LMD should be considered a factor that is involved in the obstructive phenomenon of UA in patients with OSA and PD. PMID: 30293099 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 6, 2018 Category: Sleep Medicine Authors: Bahia CMCS, Pereira JS, Lopes AJ Tags: Sleep Breath Source Type: research

Laryngopharyngeal motor dysfunction and obstructive sleep apnea in Parkinson ’s disease
ConclusionLMD should be considered a factor that is involved in the obstructive phenomenon of UA in patients with OSA and PD. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 6, 2018 Category: Respiratory Medicine Source Type: research

The use of mandibular advancement devices in obstructive sleep apnea: a proven and effective therapy.
PMID: 30284702 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 4, 2018 Category: Sleep Medicine Authors: Mintz S Tags: Sleep Breath Source Type: research

The use of mandibular advancement devices in obstructive sleep apnea: a proven and effective therapy
(Source: Sleep and Breathing)
Source: Sleep and Breathing - October 4, 2018 Category: Respiratory Medicine Source Type: research

Oxidative stress does not contribute to the release of proinflammatory cytokines through activating the Nod-like receptor protein 3 inflammasome in patients with obstructive sleep apnoea.
CONCLUSIONS: The current study suggests that oxidative stress leads to inflammation by mechanisms other than activation of the NLRP3 inflammasome in OSA patients. Furthermore, both sleep apnoea and BMI influenced the serum concentration of inflammatory mediators. PMID: 30284175 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 3, 2018 Category: Sleep Medicine Authors: Tang T, Huang Q, Liu J, Zhou X, Du J, Wu H, Li Z Tags: Sleep Breath Source Type: research

Oxidative stress does not contribute to the release of proinflammatory cytokines through activating the Nod-like receptor protein 3 inflammasome in patients with obstructive sleep apnoea
ConclusionsThe current study suggests that oxidative stress leads to inflammation by mechanisms other than activation of the NLRP3 inflammasome in OSA patients. Furthermore, both sleep apnoea and BMI influenced the serum concentration of inflammatory mediators. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 3, 2018 Category: Respiratory Medicine Source Type: research

The role of drug-induced sleep endoscopy: predicting and guiding upper airway surgery for adult OSA patients
AbstractPurposeObstructive sleep apnea (OSA) is a common sleep disorder that can be corrected with upper airway surgery. Prior to surgery, drug-induced sleep endoscopy (DISE) is routinely used to evaluate obstruction sites and severity. Evidence suggests that the findings of DISE may relate to the final surgical outcome. Therefore, we evaluated the ability of drug-induced sleep endoscopy to predict the final effect of upper airway surgery and potentially to guide surgical treatment decision-making.MethodsA retrospective analysis was conducted on 85 adult patients with OSA (50 men with mean apnea-hypopnea index [AHI] 30 &th...
Source: Sleep and Breathing - October 1, 2018 Category: Respiratory Medicine Source Type: research

The role of drug-induced sleep endoscopy: predicting and guiding upper airway surgery for adult OSA patients.
Abstract PURPOSE: Obstructive sleep apnea (OSA) is a common sleep disorder that can be corrected with upper airway surgery. Prior to surgery, drug-induced sleep endoscopy (DISE) is routinely used to evaluate obstruction sites and severity. Evidence suggests that the findings of DISE may relate to the final surgical outcome. Therefore, we evaluated the ability of drug-induced sleep endoscopy to predict the final effect of upper airway surgery and potentially to guide surgical treatment decision-making. METHODS: A retrospective analysis was conducted on 85 adult patients with OSA (50 men with mean apnea-hypopne...
Source: Sleep and Breathing - October 1, 2018 Category: Sleep Medicine Authors: Wang Y, Sun C, Cui X, Guo Y, Wang Q, Liang H Tags: Sleep Breath Source Type: research

Weight gain may affect mandibular advancement device therapy in patients with obstructive sleep apnea: a retrospective study
ConclusionsWeight gain is detrimentally associated with MAD treatment in patients with OSA. These findings suggest that regular follow-up by an experienced dentist is advisable to assess for possible worsening of OSA. Patient support to encourage weight control may be an important adjunct to MAD treatment for OSA. (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 27, 2018 Category: Respiratory Medicine Source Type: research

Weight gain may affect mandibular advancement device therapy in patients with obstructive sleep apnea: a retrospective study.
CONCLUSIONS: Weight gain is detrimentally associated with MAD treatment in patients with OSA. These findings suggest that regular follow-up by an experienced dentist is advisable to assess for possible worsening of OSA. Patient support to encourage weight control may be an important adjunct to MAD treatment for OSA. PMID: 30264356 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 27, 2018 Category: Sleep Medicine Authors: Vuorjoki-Ranta TR, Aarab G, Lobbezoo F, Tuomilehto H, Ahlberg J Tags: Sleep Breath Source Type: research

The prevalence of obstructive sleep apnea and its association with pregnancy-related health outcomes: a systematic review and meta-analysis
ConclusionsOSA is a common health issue in pregnant women. OSA is associated with various pregnancy-related health outcomes. Routine screening, early diagnosis, and effective treatment of OSA are recommended in pregnant women, particularly during mid and late pregnancy. (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 25, 2018 Category: Respiratory Medicine Source Type: research

The prevalence of obstructive sleep apnea and its association with pregnancy-related health outcomes: a systematic review and meta-analysis.
CONCLUSIONS: OSA is a common health issue in pregnant women. OSA is associated with various pregnancy-related health outcomes. Routine screening, early diagnosis, and effective treatment of OSA are recommended in pregnant women, particularly during mid and late pregnancy. PMID: 30255484 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 25, 2018 Category: Sleep Medicine Authors: Liu L, Su G, Wang S, Zhu B Tags: Sleep Breath Source Type: research

Association between obstructive sleep apnea syndrome and waist-to-height ratio
ConclusionsA high value of waist circumference, waist-to-height ratio, and BMI is associated with the presence and severity of OSAS. We have determined the cutoff values of the studied anthropometric measurements in both sexes for OSAS and severe OSAS. (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 20, 2018 Category: Respiratory Medicine Source Type: research

Association between obstructive sleep apnea syndrome and waist-to-height ratio.
CONCLUSIONS: A high value of waist circumference, waist-to-height ratio, and BMI is associated with the presence and severity of OSAS. We have determined the cutoff values of the studied anthropometric measurements in both sexes for OSAS and severe OSAS. PMID: 30238284 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 20, 2018 Category: Sleep Medicine Authors: Unal Y, Ozturk DA, Tosun K, Kutlu G Tags: Sleep Breath Source Type: research

Association between obstructive sleep apnea syndrome and waist-to-height ratio
ConclusionsA high value of waist circumference, waist-to-height ratio, and BMI is associated with the presence and severity of OSAS. We have determined the cutoff values of the studied anthropometric measurements in both sexes for OSAS and severe OSAS. (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 20, 2018 Category: Respiratory Medicine Source Type: research

REM obstructive sleep apnea: risk for adverse health outcomes and novel treatments
AbstractRapid eye movement (REM) sleep was discovered nearly 60  years ago. This stage of sleep accounts for approximately a quarter of total sleep time in healthy adults, and it is mostly concentrated in the second half of the sleep period. The majority of research on REM sleep has focused on neurocognition. More recently, however, there has been a growing int erest in understanding whether obstructive sleep apnea (OSA) during the two main stages of sleep (REM and non-REM sleep) leads to different cardiometabolic and neurocognitive risk. In this review, we discuss the growing evidence indicating that OSA during REM s...
Source: Sleep and Breathing - September 19, 2018 Category: Respiratory Medicine Source Type: research

Obstructive sleep apnea in pregnancy: performance of a rapid screening tool
ConclusionsThe SASS alone has acceptable reliability and validity, but limited predictive values. A new tool, combining the SASS and other patient characteristics (i.e., age, BMI, and bedpartner-reported snoring and breathing pauses), demonstrated improved sensitivity and specificity, and thus may have greater utility in clinical practice for predicting OSA in pregnant women. (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 19, 2018 Category: Respiratory Medicine Source Type: research

Obstructive sleep apnea in pregnancy: performance of a rapid screening tool.
CONCLUSIONS: The SASS alone has acceptable reliability and validity, but limited predictive values. A new tool, combining the SASS and other patient characteristics (i.e., age, BMI, and bedpartner-reported snoring and breathing pauses), demonstrated improved sensitivity and specificity, and thus may have greater utility in clinical practice for predicting OSA in pregnant women. PMID: 30232680 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 19, 2018 Category: Sleep Medicine Authors: Balserak BI, Zhu B, Grandner MA, Jackson N, Pien GW Tags: Sleep Breath Source Type: research

REM obstructive sleep apnea: risk for adverse health outcomes and novel treatments.
Abstract Rapid eye movement (REM) sleep was discovered nearly 60 years ago. This stage of sleep accounts for approximately a quarter of total sleep time in healthy adults, and it is mostly concentrated in the second half of the sleep period. The majority of research on REM sleep has focused on neurocognition. More recently, however, there has been a growing interest in understanding whether obstructive sleep apnea (OSA) during the two main stages of sleep (REM and non-REM sleep) leads to different cardiometabolic and neurocognitive risk. In this review, we discuss the growing evidence indicating that OSA duri...
Source: Sleep and Breathing - September 19, 2018 Category: Sleep Medicine Authors: Varga AW, Mokhlesi B Tags: Sleep Breath Source Type: research