The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy
Nature Reviews Cardiology, Published online: 24 February 2021; doi:10.1038/s41569-021-00517-4In this Review, Simons and colleagues present the current knowledge of organ-specific signalling pathways involved in the maintenance of endothelial quiescence and the pathologies associated with their disruption. This knowledge will assist the development of innovative preventive strategies and identification of new therapeutic targets. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 24, 2021 Category: Cardiology Authors: Nicolas Ricard Sabine Bailly Christophe Guignabert Michael Simons Source Type: research

Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases
Nature Reviews Cardiology, Published online: 22 February 2021; doi:10.1038/s41569-021-00511-wIn this Review, Ren and colleagues summarize the latest advances in understanding the unfolded protein response and endoplasmic reticulum stress in the pathogenesis of cardiovascular disease and discuss potential therapeutic strategies aimed at restoring endoplasmic reticulum proteostasis in cardiovascular diseases. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 22, 2021 Category: Cardiology Authors: Jun Ren Yaguang Bi James R. Sowers Claudio Hetz Yingmei Zhang Source Type: research

GRK5 linked to cardiac dysfunction and leukocyte recruitment after MI
Nature Reviews Cardiology, Published online: 22 February 2021; doi:10.1038/s41569-021-00533-4The G protein-coupled receptor kinase 5 contributes to impaired cardiac function and remodelling and promotes immune cell recruitment after myocardial infarction in mice. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 22, 2021 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Calcific aortic valve disease: turning therapeutic discovery up a notch
Nature Reviews Cardiology, Published online: 19 February 2021; doi:10.1038/s41569-021-00528-1Valve replacement is currently the only treatment for calcific aortic valve disease. Studies of an uncommon, genetic form of aortic valve disease have yielded in vitro and mouse models of the disease and a transcriptomic disease signature. Machine learning-driven screens for compounds that normalize this signature promise to enable medical management of aortic valve disease. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 19, 2021 Category: Cardiology Authors: Suya Wang William T. Pu Source Type: research

A novel cardioprotective function for DRP1 inhibition
Nature Reviews Cardiology, Published online: 17 February 2021; doi:10.1038/s41569-021-00530-7A new study identifies a small-molecule inhibitor of a mitochondrial fission protein that reduces PCSK9 secretion and atherosclerotic plaque formation. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 17, 2021 Category: Cardiology Authors: Andrew Robson Source Type: research

Transient mesenchymal activation of endothelial cells after MI
Nature Reviews Cardiology, Published online: 15 February 2021; doi:10.1038/s41569-021-00529-0In the first 2 weeks after myocardial infarction, endothelial cells can undergo a partial and transient activation of a mesenchymal phenotype before returning to an endothelial state. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 15, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Diffuse myocardial fibrosis: mechanisms, diagnosis and therapeutic approaches
Nature Reviews Cardiology, Published online: 10 February 2021; doi:10.1038/s41569-020-00504-1In this Review, Díez and colleagues summarize the mechanisms of diffuse myocardial fibrosis in heart failure, discuss imaging techniques and circulating biomarkers to characterize the variability of this lesion in patients, and highlight the available and potential future therapeutic strategies for personalizing the prevention and reversal of diffuse myocardial fibrosis. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 10, 2021 Category: Cardiology Authors: Bego ña López Susana Ravassa Mar ía U. Moreno Gorka San Jos é Javier Beaumont Arantxa Gonz ález Javier D íez Source Type: research

New insights into the genetics of cardiomyopathies
Nature Reviews Cardiology, Published online: 09 February 2021; doi:10.1038/s41569-021-00526-3Common genetic variants, modifiable risk factors and a polygenic risk score all have important implications for disease susceptibility, severity and variability in hypertrophic cardiomyopathy. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 9, 2021 Category: Cardiology Authors: Andrew Robson Source Type: research

Microthrombi cause cardiac injury in COVID-19
Nature Reviews Cardiology, Published online: 04 February 2021; doi:10.1038/s41569-021-00524-5Microthrombi cause cardiac injury in COVID-19 (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 4, 2021 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Gene enhancer variation modifies cardiomyopathy
Nature Reviews Cardiology, Published online: 04 February 2021; doi:10.1038/s41569-021-00523-6Gene enhancer variation modifies cardiomyopathy (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 4, 2021 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Boosting stem cell vascular regenerative capacity
Nature Reviews Cardiology, Published online: 04 February 2021; doi:10.1038/s41569-021-00525-4Boosting stem cell vascular regenerative capacity (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 4, 2021 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Myocardial stunning and hibernation revisited
Nature Reviews Cardiology, Published online: 02 February 2021; doi:10.1038/s41569-021-00506-7In this Review, Heusch summarizes the pathophysiology of myocardial stunning and hibernation and highlights potential treatments and clinical implications. A better understanding of these characteristic reperfusion phenomena is important for the potential indication for revascularization and its consequences in patients with chronic coronary syndromes. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 2, 2021 Category: Cardiology Authors: Gerd Heusch Source Type: research

Machine learning predicts risk in ACS
Nature Reviews Cardiology, Published online: 02 February 2021; doi:10.1038/s41569-021-00521-8A new machine learning risk-stratification model accurately predicts the 1-year risk of ischaemic and major bleeding events in patients with an acute coronary syndrome and might be useful to guide clinical decision-making and optimize the quality of care of these patients. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 2, 2021 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Artificial intelligence-enhanced electrocardiography in cardiovascular disease management
Nature Reviews Cardiology, Published online: 01 February 2021; doi:10.1038/s41569-020-00503-2In this Review, Friedman and colleagues summarize the use of artificial intelligence-enhanced electrocardiography in the detection of cardiovascular disease in at-risk populations, discuss its implications for clinical decision-making in patients with cardiovascular disease and critically appraise potential limitations and unknowns. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - February 1, 2021 Category: Cardiology Authors: Konstantinos C. Siontis Peter A. Noseworthy Zachi I. Attia Paul A. Friedman Source Type: research

Cardiovascular health concerns in sexual and gender minority populations
Nature Reviews Cardiology, Published online: 28 January 2021; doi:10.1038/s41569-021-00518-3Growing evidence indicates that sexual and gender minority populations might be at greater risk of cardiovascular disease than the general population. Additional population and clinical health research is needed to inform the development of tailored, evidence-based interventions to promote the cardiovascular health of sexual and gender minority populations. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 28, 2021 Category: Cardiology Authors: Billy A. Caceres Carl G. Streed Jr Source Type: research

Cardiac macrophages regulate lymphatic vessel growth during heart development
Nature Reviews Cardiology, Published online: 28 January 2021; doi:10.1038/s41569-021-00519-2Tissue-resident macrophages form direct interactions with lymphatic endothelial cells and regulate the growth and sprouting of lymphatic vessels during development of the mammalian cardiac vasculature. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 28, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Targeted delivery of therapeutic agents to the heart
Nature Reviews Cardiology, Published online: 26 January 2021; doi:10.1038/s41569-020-00499-9For therapeutic materials to be delivered to the heart, several barriers need to be overcome. In this Review, Ishikawa and colleagues discuss strategies for targeted delivery of therapeutic materials to the heart, including the use of adeno-associated viruses and exosomes, with a focus on agents directed at modifying gene expression. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 26, 2021 Category: Cardiology Authors: Susmita Sahoo Taro Kariya Kiyotake Ishikawa Source Type: research

Publisher Correction: Cellular and molecular pathobiology of heart failure with preserved ejection fraction
Nature Reviews Cardiology, Published online: 21 January 2021; doi:10.1038/s41569-021-00516-5Publisher Correction: Cellular and molecular pathobiology of heart failure with preserved ejection fraction (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 21, 2021 Category: Cardiology Authors: Sumita Mishra David A. Kass Source Type: research

Pathophysiology of sepsis-induced cardiomyopathy
Nature Reviews Cardiology, Published online: 20 January 2021; doi:10.1038/s41569-020-00492-2In this Review, Hollenberg and Singer explore the definition, epidemiology, diagnosis and pathophysiology of septic cardiomyopathy, with an emphasis on how best to interpret this condition in the clinical context in order to optimize interventions and improve outcomes. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 20, 2021 Category: Cardiology Authors: Steven M. Hollenberg Mervyn Singer Source Type: research

The evolving cardiac lymphatic vasculature in development, repair and regeneration
Nature Reviews Cardiology, Published online: 18 January 2021; doi:10.1038/s41569-020-00489-xThis Review summarizes the latest knowledge on cardiac lymphatic development, structure and function, discusses the role of the cardiac lymphatics after myocardial injury during fibrotic repair and regeneration, and highlights the therapeutic potential of targeting the cardiac lymphatics in myocardial infarction. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 18, 2021 Category: Cardiology Authors: Konstantinos Klaourakis Joaquim M. Vieira Paul R. Riley Source Type: research

MI-derived alarmins activate B cells to accelerate atherosclerosis
Nature Reviews Cardiology, Published online: 18 January 2021; doi:10.1038/s41569-021-00515-6Alarmins released by infarcted myocardium stimulate B cells to differentiate into antibody-producing plasma cells, which then remotely drive the progression of atherosclerosis by producing autoantibodies that accumulate in pre-existing atherosclerotic plaques, increasing local inflammation and accelerating the progression towards a vulnerable plaque phenotype. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 18, 2021 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

ACEi reduces hypertension-induced hyperinflammation in COVID-19
Nature Reviews Cardiology, Published online: 18 January 2021; doi:10.1038/s41569-021-00512-9Antihypertensive therapy, particularly with the use of an angiotensin-converting enzyme inhibitor, improves outcomes in patients with hypertension and SARS-CoV-2 infection, who are susceptible to hyperinflammation and severe outcomes with COVID-19. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 18, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Hydralazine reduces myocardial infarct size
Nature Reviews Cardiology, Published online: 18 January 2021; doi:10.1038/s41569-021-00514-7A new study shows that hydralazine, a drug used for the treatment of resistant hypertension and heart failure, can inhibit mitochondrial fission, thereby reducing cardiomyocyte death and myocardial infarct size after ischaemia–reperfusion injury in mice. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 18, 2021 Category: Cardiology Authors: Andrew Robson Source Type: research

Rebalancing the pyruvate–lactate axis to treat heart failure
Nature Reviews Cardiology, Published online: 18 January 2021; doi:10.1038/s41569-021-00513-8New research shows that the pyruvate–lactate axis is an important regulatory node for cardiac homeostasis and function and that alteration of this axis is an early event in cardiomyocyte hypertrophy and heart failure. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 18, 2021 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

SIRT6 slows VSMC senescence and atherogenesis
Nature Reviews Cardiology, Published online: 13 January 2021; doi:10.1038/s41569-021-00510-xSIRT6 slows VSMC senescence and atherogenesis (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 13, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Brown fat promotes cardiometabolic health
Nature Reviews Cardiology, Published online: 13 January 2021; doi:10.1038/s41569-021-00508-5Brown fat promotes cardiometabolic health (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 13, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Transcriptional atlas of mouse heart regeneration
Nature Reviews Cardiology, Published online: 13 January 2021; doi:10.1038/s41569-021-00509-4Transcriptional atlas of mouse heart regeneration (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 13, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

A protective role for eosinophils in MI
Nature Reviews Cardiology, Published online: 12 January 2021; doi:10.1038/s41569-021-00507-6A new study identifies a protective function for eosinophils after myocardial infarction. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 12, 2021 Category: Cardiology Authors: Andrew Robson Source Type: research

Cellular and molecular pathobiology of heart failure with preserved ejection fraction
Nature Reviews Cardiology, Published online: 11 January 2021; doi:10.1038/s41569-020-00480-6Heart failure with preserved ejection fraction (HFpEF) affects half of all patients with heart failure worldwide. In this Review, Mishra and Kass and provide a roadmap of the signalling pathways and mechanisms of HFpEF that are being characterized and which might lead to more patient-specific therapies and improved clinical outcomes. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 11, 2021 Category: Cardiology Authors: Sumita Mishra David A. Kass Source Type: research

Reduced lymphatic drainage promotes HFpEF and atherosclerosis
Nature Reviews Cardiology, Published online: 07 January 2021; doi:10.1038/s41569-021-00505-8Impairment of drainage by the lymphatic system is involved in the accumulation of interstitial fluid in patients with heart failure with preserved ejection fraction and the development and progression of atherosclerotic plaque. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 7, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Mouse gastruloids take heart
Nature Reviews Cardiology, Published online: 07 January 2021; doi:10.1038/s41569-020-00501-4Mouse embryonic organoids that model cardiac development ex vivo could be used as a high-throughput, experimentally tractable system to evaluate crucial cell populations and environmental factors that contribute to normal and abnormal cardiogenesis. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 7, 2021 Category: Cardiology Authors: Deepak Srivastava Todd C. McDevitt Source Type: research

Clarification of the definition of hypoplastic left heart syndrome
Nature Reviews Cardiology, Published online: 06 January 2021; doi:10.1038/s41569-020-00500-5There is still no consensus on the anatomical combinations that make up the so-called hypoplastic left heart syndrome. We argue that an intact ventricular septum should now be part of the definition. Addition of this feature is necessary if accurate predictions are to be made about the morphogenesis of the condition. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 6, 2021 Category: Cardiology Authors: Robert H. Anderson Diane E. Spicer Adrian Crucean Source Type: research

The neuropsychology of statin intolerance
Nature Reviews Cardiology, Published online: 06 January 2021; doi:10.1038/s41569-020-00502-3Statin nocebo effects have been demonstrated in numerous randomized, double-blind, placebo-controlled and active-controlled trials. Emerging evidence suggests that brain pathways might mediate statin nocebo hyperalgesia. Evidence-based pain-management approaches can be used to manage nocebo symptoms that occur during statin therapy. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - January 6, 2021 Category: Cardiology Authors: Jennifer G. Robinson Source Type: research

Epidemiology and management of aortic disease: aortic aneurysms and acute aortic syndromes
Nature Reviews Cardiology, Published online: 22 December 2020; doi:10.1038/s41569-020-00472-6In this Review, Bossone and Eagle discuss the epidemiology, management and outcomes of the most common aortic diseases: aortic aneurysms and acute aortic syndromes, including aortic dissection. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 22, 2020 Category: Cardiology Authors: Eduardo Bossone Kim A. Eagle Source Type: research

Exosome-derived microRNAs improve cardiac function
Nature Reviews Cardiology, Published online: 21 December 2020; doi:10.1038/s41569-020-00498-wA new study identifies microRNAs that are enriched in exosomes secreted from cardiosphere-derived cells and which are associated with cardiac repair in pigs and humans with dilated cardiomyopathy. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 21, 2020 Category: Cardiology Authors: Andrew Robson Source Type: research

Novel cardioprotective lymphatic signal identified
Nature Reviews Cardiology, Published online: 21 December 2020; doi:10.1038/s41569-020-00495-zNovel cardioprotective lymphatic signal identified (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 21, 2020 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Deleterious role of IDO1 in cardiac repair
Nature Reviews Cardiology, Published online: 21 December 2020; doi:10.1038/s41569-020-00497-xDeleterious role of IDO1 in cardiac repair (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 21, 2020 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Lipid metabolism in peripartum cardiomyopathy
Nature Reviews Cardiology, Published online: 21 December 2020; doi:10.1038/s41569-020-00496-yLipid metabolism in peripartum cardiomyopathy (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 21, 2020 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Systems biology in cardiovascular disease: a multiomics approach
Nature Reviews Cardiology, Published online: 18 December 2020; doi:10.1038/s41569-020-00477-1In this Review, Mayr and colleagues describe the growing number of omic techniques, discuss their strengths and weaknesses, outline network theory, and highlight exemplars of novel approaches that combine gene regulatory and co-expression networks, proteomics, metabolomics, lipidomics and phenomics with informatics techniques to provide new insights into cardiovascular disease. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 18, 2020 Category: Cardiology Authors: Abhishek Joshi Marieke Rienks Konstantinos Theofilatos Manuel Mayr Source Type: research

Cardiac optogenetics: a decade of enlightenment
Nature Reviews Cardiology, Published online: 18 December 2020; doi:10.1038/s41569-020-00478-0In this Review, Entcheva and Kay discuss a decade of important developments and applications of optogenetics to the heart, focusing on near-term and longer-term clinical translation of this technology in cardiology. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 18, 2020 Category: Cardiology Authors: Emilia Entcheva Matthew W. Kay Source Type: research

Plaque-reactive autoantibody A12 protects against atherosclerosis
Nature Reviews Cardiology, Published online: 15 December 2020; doi:10.1038/s41569-020-00494-0A new study identifies the mitochondrial protein ALDH4A1 as a potential biomarker of atherosclerosis and as a target antigen of protective autoantibody A12, which might have therapeutic potential. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 15, 2020 Category: Cardiology Authors: Andrew Robson Source Type: research

The IL-1 trap rilonacept resolves and prevents recurrent pericarditis
Nature Reviews Cardiology, Published online: 01 December 2020; doi:10.1038/s41569-020-00491-3In patients with recurrent pericarditis, treatment with rilonacept, an engineered fusion protein that acts as an IL-1 trap, leads to a rapid resolution of recurrent pericarditis episodes and reduces the risk of pericarditis recurrence. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 1, 2020 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Iron supplementation reduces re-hospitalization for heart failure
Nature Reviews Cardiology, Published online: 01 December 2020; doi:10.1038/s41569-020-00490-4In the AFFIRM-AHF trial, the use of intravenous ferric carboxymaltose in patients with acute heart failure and iron deficiency was associated with a reduction in hospitalization for heart failure and cardiovascular death. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 1, 2020 Category: Cardiology Authors: Andrew Robson Source Type: research

Drugs targeting the sarcomere in heart failure and hypertrophic cardiomyopathy
Nature Reviews Cardiology, Published online: 01 December 2020; doi:10.1038/s41569-020-00488-yOmecamtiv mecarbil (a myosin activator) and mavacamten (a myosin inhibitor) have beneficial effects in patients with heart failure with reduced ejection fraction or obstructive hypertrophic cardiomyopathy, respectively. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - December 1, 2020 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Rivaroxaban in AF with a prosthetic mitral valve
Nature Reviews Cardiology, Published online: 24 November 2020; doi:10.1038/s41569-020-00484-2Rivaroxaban in AF with a prosthetic mitral valve (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - November 24, 2020 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Sotagliflozin reduces adverse cardiovascular events
Nature Reviews Cardiology, Published online: 24 November 2020; doi:10.1038/s41569-020-00486-0Sotagliflozin reduces the risk of adverse cardiovascular events in patients with type 2 diabetes mellitus and chronic kidney disease or worsening heart failure according to the SCORED and SOLOIST-WHF trials. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - November 24, 2020 Category: Cardiology Authors: Andrew Robson Source Type: research

ANGPTL3 inhibition for hypercholesterolaemia
Nature Reviews Cardiology, Published online: 24 November 2020; doi:10.1038/s41569-020-00483-3ANGPTL3 inhibition for hypercholesterolaemia (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - November 24, 2020 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Polypill plus aspirin reduces the risk of cardiovascular disease
Nature Reviews Cardiology, Published online: 24 November 2020; doi:10.1038/s41569-020-00485-1In the TIPS-3 trial, a single polypill comprising blood-pressure-lowering and cholesterol-lowering drugs, together with a daily dose of aspirin, reduced cardiovascular events in people at risk of cardiovascular disease. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - November 24, 2020 Category: Cardiology Authors: Andrew Robson Source Type: research

Cryoablation as first-line strategy in AF
Nature Reviews Cardiology, Published online: 24 November 2020; doi:10.1038/s41569-020-00487-zFindings from two clinical trials indicate that cryoablation as first-line treatment is superior to drug therapy for the prevention of atrial arrhythmia recurrence in patients with paroxysmal atrial fibrillation. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - November 24, 2020 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research

Lipid lowering remains effective in older patients
Nature Reviews Cardiology, Published online: 24 November 2020; doi:10.1038/s41569-020-00482-4Lipid lowering remains effective in older patients (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - November 24, 2020 Category: Cardiology Authors: Gregory B. Lim Source Type: research