Primary Sjogren's syndrome independently promotes premature subclinical atherosclerosis

CONCLUSIONS: Subclinical atherosclerosis occurs earlier and more severely in patients with pSS. The difference in cIMT between pSS and controls seems mainly driven by patients with OI, suggesting that this subgroup is particularly at risk. OxLDL ab might protect against atherosclerotic progression in patients with pSS. CVR stratification and preventive medications such as Hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors should be discussed and further longitudinal studies are needed.PMID:38663882 | DOI:10.1136/rmdopen-2023-003559

Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Nadine Zehrfeld Malin Abelmann Sabrina Benz Clara Luisa Zippel Sonja Beider Emelie Kramer Tabea Seeliger Georgios Sogkas Vega G ödecke Gerrit Ahrenstorf Franz Paul Armbruster Thomas Skripuletz Torsten Witte Anselm Arthur Derda Kristina Sonnenschein Diana Source Type: research