Myocardial contractility recovery following acute pressure unloading after transcatheter aortic valve intervention (TAVI)  in patients with severe aortic stenosis and different left ventricular geometry: a multilayer longitudinal strain echocardiographicanalysis
AbstractAim of the present study was to describe the left ventricular longitudinal strain (LS) in all myocardial layers in patients with severe aortic stenosis (AS), preserved left ventricular ejection fraction (LVEF) in different LV geometry and to compare LS analysis before and early after acute LV unloading provided by transcatheter aortic valve implantation (TAVI). 68 patients were enrolled. LS was measured from the endocardial layer (Endo-LS), epicardial layer (Epi-LS) and full thickness of myocardium (Transmural-LS) before and after TAVI. Patients were divided in two groups accordingly with relative wall thickness (R...
Source: The International Journal of Cardiovascular Imaging - November 30, 2020 Category: Radiology Source Type: research

Use of spectral tracking technique to evaluate the changes in left ventricular function in patients undergoing chemotherapy for colorectal cancer
AbstractTo evaluate the changes in left ventricular myocardial function in patients with colorectal cancer undergoing chemotherapy with mFOLFOX6 (oxaliplatin  + 5-fluorouracil + calcium folinate) using three-dimensional speckle-tracking echocardiography (3D-STE). Data were collected from 30 patients diagnosed with colorectal cancer in our hospital treated with mFOLFOX6. We used 3D-STE to measure the following parameters of left ventricle function : global longitudinal strain (GLS), global area strain (GAS), global circumferential strain (GCS), global radial strain (GRS), and left ventricular twi...
Source: The International Journal of Cardiovascular Imaging - November 27, 2020 Category: Radiology Source Type: research

Correlation between computed tomography adapted leaman score and computed tomography liver and spleen attenuation parameters for non-alcoholic fatty liver disease as well as respective inflammatory mediators
AbstractMetabolic syndrome is a primary driver of vascular inflammation, plaque development, and atherosclerotic disease. The Computed Tomography-adapted Leaman Score (CT-LeSc) has been shown to be an independent predictor of cardiac events in coronary artery disease (CAD) patients but has never been studied for broader applicability. Non-alcoholic fatty liver disease (NAFLD) is associated with similar systemic inflammatory processes as CAD, and its presence as assessed by Computed Tomography Liver and Spleen Attenuation (CT-LSA) may impact on the extension of the CT-LeSc. The purpose of this study was to investigate the a...
Source: The International Journal of Cardiovascular Imaging - November 25, 2020 Category: Radiology Source Type: research

Comprehensive assessment of coronary computed tomography angiography by using Leaman and Leiden score in overweight and obese patients
This study compares the CCTA Leaman and Leiden score between overweight and obese populations in addition to their associated baseline characteristics. All patients who underwent CCTA within the last 1  year from a single institution were included for initial analysis. Body mass index (BMI) was used to classify patients who were overweight (25.0 to  5 which may indicate a higher risk for adverse cardiovascular outcomes. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 25, 2020 Category: Radiology Source Type: research

Prognostic importance of coincidental coronary artery calcification on FDG-PET/CT oncology studies
AbstractCoronary artery calcification (CAC) on body CT imaging is considered a coincidental finding in cancer patients. In order to determine the significance of CAC in cancer patients we evaluated the prognostic utility of CAC detected on oncology FDG-PET/CT studies. A retrospective study was performed of consecutive FDG-PET/CT studies from January to March 2011. CAC was identified on the CT portion of FDG/PET-CT studies. Chart review documented statin use, the Framingham risk score (FRS) (includes age, diabetes, hypertension, dyslipidemia and smoking), the primary malignancy and metastases. The primary end point was a co...
Source: The International Journal of Cardiovascular Imaging - November 25, 2020 Category: Radiology Source Type: research

A novel application of pulmonary transit time to differentiate between benign and malignant pulmonary nodules using myocardial contrast echocardiography
AbstractMalignant pulmonary nodules (PNs) are often accompanied by vascular dilatation and structural abnormalities. Pulmonary transit time (PTT) measurement by contrast echocardiograghy has used to assess the cardiopulmonary function and pulmonary vascular status, such as hepatopulmonary syndrome and pulmonary arteriovenous fistula, but has not yet been attempted in  the diagnosis and differential diagnosis of PNs. The aim of this work was to evaluate the feasibility and performance of myocardial contrast echocardiography (MCE) for differentiating malignant PNs from benign ones. The study population consisted of 201 ...
Source: The International Journal of Cardiovascular Imaging - November 24, 2020 Category: Radiology Source Type: research

Prediction of response to cardiac resynchronization therapy using a multi-feature learning method
AbstractWe hypothesized that a multiparametric evaluation, based on the combination of electrocardiographic and echocardiographic parameters, could enhance the appraisal of the likelihood of reverse remodeling and prognosis of favorable clinical evolution to improve the response of cardiac resynchronization therapy (CRT). Three hundred and twenty-three heart failure patients were retrospectively included in this multicenter study. 221 patients (68%) were responders, defined by a decrease in left ventricle end-systolic volume ≥15% at the 6-month follow-up. In addition, strain data coming from echocardiography were analyz...
Source: The International Journal of Cardiovascular Imaging - November 23, 2020 Category: Radiology Source Type: research

Value of territorial work efficiency estimation in non-ST-segment-elevation acute coronary syndrome: a study with non-invasive left ventricular pressure –strain loops
This study utilized non-invasive LV pressure –strain loops to evaluate territorial myocardial work efficiency (WE) for identifying obstructive coronary artery stenosis, in patients with non-obstructive or obstructive coronary artery stenosis NSTE-ACS, the latter with or without occlusion. Global and territorial longitudinal strain (LS) analy ses were performed via speckle-tracking imaging before coronary angiography. LV pressure–strain loops estimated global and territorial myocardial work index (MWI), constructive work (CW), wasted work (WW), and WE. Receiver operating characteristic curve analysis was used to...
Source: The International Journal of Cardiovascular Imaging - November 23, 2020 Category: Radiology Source Type: research

Left ventricular strain values using 3D speckle-tracking echocardiography in healthy adults aged 20 to 72  years
AbstractThree dimensional speckle tracking echocardiography (3D-STE) is a novel modality for the assessment of left ventricular strain (LVS). The aim of our study is to provide single vendor normative strain values measured with 3D-STE in healthy adult caucasians. One hundred fifty-five healthy subjects aged 20 to 72  years (≥ 28 subjects per decile) were prospectively included and examined with 2D and 3D transthoracic echocardiography. In 105 both 3D and 2D-STE were feasible (71%, mean age 44 ± 14 years, 51% female). Mean 3D tangential strain (3D-TS) was − 32&th...
Source: The International Journal of Cardiovascular Imaging - November 23, 2020 Category: Radiology Source Type: research

Prevalence of newly diagnosed sarcoidosis in patients with ventricular arrhythmias: a cardiac magnetic resonance and 18F-FDG cardiac PET study
In this study, we sought to determine the prevalence of primary CS and the relationship between myocardial 18F-FDG uptake and LGE in patients with VT without known sarcoidosis. We retrospectively identified 67 patients without known sarcoidosis or active ischemic heart disease (i.e. significant ischemic disease that had not been previously revascularized) referred for both CMR and PET for evaluation of VT. Standard cine- and LGE- CMR and cardiac PET protocols were used. Myocardial LGE was defined as signal intensity  >  5 SDs above the mean signal intensity of normal myocardium. Cardiac PET images were con...
Source: The International Journal of Cardiovascular Imaging - November 22, 2020 Category: Radiology Source Type: research

Impact of optical coherence tomography findings on clinical outcomes in ST-segment elevation myocardial infarction patients: a MATRIX (Minimizing Adverse Hemorrhagic Events by Trans-radial Access Site and angioX) OCT sub-study
AbstractPurposeTo investigate the association of the degree of stent expansion, as assessed by optical coherence tomography (OCT), following stent implantation, and clinical outcomes in ST-segment elevation myocardial infarction (STEMI) patients.MethodsSTEMI patients from the MATRIX (Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and angioX) OCT study were selected; Clinical outcomes were collected through 1  year. Stent expansion index is a minimum stent area (MSA) divided by average lumen area (average of proximal and distal reference lumen area). The following variables were measured: MSA ( &thin...
Source: The International Journal of Cardiovascular Imaging - November 22, 2020 Category: Radiology Source Type: research

PET/CT in a patient with cardiac paraganglioma
AbstractA 22-year-old female with SDHB-positive who presented with palpitation and hypertension after adrenalectomy was performed18F-FDG PET/CT to detect the primary ectopic pheochromocytoma (PCC) and rule out metastasis. PET/CT is useful for detecting and localizing the primary ectopic PCC. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 20, 2020 Category: Radiology Source Type: research

Automated estimation of echocardiogram image quality in hospitalized patients
This study applied a machine learning model for automated transthoracic echo (TTE) image quality scoring in three inpatient groups. Our objectives were: (1) Assess the feasibility of a machine learning model for echo image quality analysis, (2) Establish the comprehensiveness of real-world TTE rep orting by clinical group, and (3) Determine the relationship between machine learning image quality and comprehensiveness of TTE reporting. A machine learning model was developed and applied to TTEs from three matched cohorts for image quality of nine standard views. Case TTEs were comprehensive stu dies in mechanically ventilate...
Source: The International Journal of Cardiovascular Imaging - November 19, 2020 Category: Radiology Source Type: research

Unrecognized pulmonary arterial hypertension in hospitalized patients
AbstractPulmonary hypertension (PH) is an underdiagnosed and potentially fatal condition. The utility of screening for PH in hospitalized patients undergoing echocardiography is unknown. The goal of this study was to determine the prevalence of undiagnosed pulmonary hypertension (PH) and probable pulmonary arterial hypertension (PAH) in hospitalized patients undergoing echocardiography for any indication. All hospitalized patients undergoing echocardiography were identified and echocardiographs reviewed prospectively for the presence of a tricuspid regurgitant (TR) jet. Electronic medical records (EMR) of patients with a T...
Source: The International Journal of Cardiovascular Imaging - November 19, 2020 Category: Radiology Source Type: research

Imaging in COVID-19-related myocardial injury
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS- CoV-2), previously named “2019 novel coronavirus” (2019-nCoV) is an emerging disease and a major public health issue. At the moment, little is known, except that its spread is on a steady upward trend. That is the reason why it was declared pandemic since March 11th, 2020. Respiratory symptoms dominate the clinical mani festations of the virus, but in a few patients also other organs are involved, such as their heart. This review article provides an overview of the existing literature regarding imaging of heart injury during COVID-19 acute infection...
Source: The International Journal of Cardiovascular Imaging - November 19, 2020 Category: Radiology Source Type: research

Myocardial involvement in eosinophilic granulomatosis with polyangiitis evaluated with cardiopulmonary magnetic resonance
This study aimed to characterise myocardial and pulmonary manifestations of EGPA, and their relationship. Prospective comprehensive cardiopulmonary investigation, including a novel combined cardiopulmonary magnetic resonance imaging (MRI) technology, was performed in 13 patients with stable EGPA. Comparison was made with 11 prospectively recruited matched healthy volunteers. Stable EGPA was associated with focal replacement and diffuse interstitial myocardial fibrosis (myocardial extracellular volume 26.9% vs. 24.7%; p  = 0.034), which drove a borderline increase in left ventricular mass (56  &plu...
Source: The International Journal of Cardiovascular Imaging - November 19, 2020 Category: Radiology Source Type: research

Does left ventricular function predict cardiac outcome in Anderson –Fabry disease?
AbstractIn Anderson –Fabry disease (AFD) the impact of left ventricular (LV) function on cardiac outcome is unknown. Noninvasive LV pressure–strain loop analysis is a new echocardiographic method to estimate myocardial work (MW). We aimed to evaluate whether LV function was associated with outcome and whether MW ha d a prognostic value in AFD. Ninety-six AFD patients (41.8 ± 14.7 years, 43.7% males) with normal LV ejection fraction were retrospectively evaluated. Inclusion criteria were sinus rhythm and ≥ 2-year follow-up. Standard echocardiography measurements, myocardial me...
Source: The International Journal of Cardiovascular Imaging - November 19, 2020 Category: Radiology Source Type: research

Left atrial structural and functional remodeling following balloon mitral valvuloplasty
AbstractMitral stenosis (MS) is associated with left atrial (LA) functional and morphological changes as a result of chronic increase in LA pressure. Relieving the mitral obstruction via balloon mitral valvuloplasty (BMV) might be associated with LA structural and functional remodeling. To study alterations of LA volume and functions 1 year following successful BMV in patients with isolated rheumatic severe mitral stenosis. Thirty patients (median age 33 years, 22 women) with severe rheumatic MS were included in the study. Using biplane method, trans-thoracic 2D echocardiography was used to estimate LA volume indexed to bo...
Source: The International Journal of Cardiovascular Imaging - November 19, 2020 Category: Radiology Source Type: research

The relation between left ventricular global longitudinal strain and troponin levels in patients hospitalized with COVID-19 pneumonia
AbstractLeft ventricular global longitudinal strain (LVGLS) from two-dimensional speckle-tracking echocardiography (2D-STE) provides a more accurate estimation of subclinical myocardial dysfunction. In patients with COVID-19, elevated high sensitive troponin (hs-TnI) levels are frequent independent from the underlying cardiovascular disease. However, the relationship between high troponin levels and LVGLS in such patients remains unknown. We aimed to investigate the relation between troponin levels and LVGLS values in patients with COVID-19. A total of thirty-eight patients diagnosed with COVID-19 pneumonia who underwent e...
Source: The International Journal of Cardiovascular Imaging - November 18, 2020 Category: Radiology Source Type: research

Impact of clinical presentations on lipid core plaque assessed by near-infrared spectroscopy intravascular ultrasound
In conclusion, LCP assessed by NIRS-IVUS, a surrogate of coronary plaque vulnerability, was significantly different according to the clinical presentations such as CCS, UA, NSTEMI, and STEMI. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 17, 2020 Category: Radiology Source Type: research

Contemporary use of coronary computed tomography angiography in the planning of percutaneous coronary intervention
AbstractPlanning of percutaneous coronary interventions (PCI) is largely based on anatomical information obtained with invasive coronary angiography. Over the last decade, intracoronary information obtained from both imaging and physiological techniques has gradually gained recognition for this purpose. Yet, coronary computed tomography angiography (CCTA) is still ignored by most interventionalists as a tool in the planning of PCI strategies. This has occurred despite major developments in CCTA, including physiological assessment, plaque characterisation, etc. Furthermore, it is foreseeable that many more patients referred...
Source: The International Journal of Cardiovascular Imaging - November 17, 2020 Category: Radiology Source Type: research

Quantification of calcium burden by coronary CT angiography compared to optical coherence tomography
AbstractCoronary artery calcifications (CAC) are frequently observed in patients referred for coronary CT angiography (CTA). Calcification volume (in mm3) can accurately be assessed during catheterization by optical coherence tomography (OCT). The aim of the present study was to investigate the accuracy of CTA-derived assessment of calcification volume as compared with OCT. 66 calcified plaques (32 vessels) from 31 patients undergoing OCT-guided PCI with coronary CT acquired as a standard of care were included. Coronary CT and OCT images were matched using fiduciary points. Calcified plaques were reconstructed in three dim...
Source: The International Journal of Cardiovascular Imaging - November 17, 2020 Category: Radiology Source Type: research

Feasibility, safety and long-term outcomes of complex left main bifurcation treatment using the nano-inverted-t stenting: a multicentre prospective registry
We present the 3-year multicentre registry outcomes of dual stenting using ultra-thin strut stents and the Nano-Inverted-T (NIT) technique in complex unprotected true LM bifurcation disease. We analysed the procedural and medical data of consecutive patients enrolled between 1st January 2014 and 1st December 2019 in a multicentre registry for complex LM bifurcation disease treated with the double stenting technique called NIT due contraindications and/ or refusal to surgical treatment. Target lesion failure (TLF) was defined as the composite of cardiovascular death, target-vessel MI (TVMI) and clinically driven target lesi...
Source: The International Journal of Cardiovascular Imaging - November 16, 2020 Category: Radiology Source Type: research

Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
AbstractThe purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102  patients with clinical suspicion of acute myocarditis underwent cardiac magnetic resonance (CMR) on a 1.5 T scanner. Protocol included cine-SSFP, T2-weighted STIR, T2 mapping, early and late gadolinium enhancement and T1 mapping acquired before and after gadolinium administration. The degree of a greement has been calculated with Cohen’s K test. 42 patients also underwent endomyocar...
Source: The International Journal of Cardiovascular Imaging - November 15, 2020 Category: Radiology Source Type: research

Multiclass machine learning vs. conventional calculators for stroke/CVD risk assessment using carotid plaque predictors with coronary angiography scores as gold standard: a 500 participants study
AbstractMachine learning (ML)-based algorithms for cardiovascular disease (CVD) risk assessment have shown promise in clinical decisions. However, they usually predict binary events using only conventional risk factors. Our overall goal was to develop the “multiclass machine learning (MCML)-based algorithms” (labelled as AtheroEdge 3.0ML) and assess whether considering carotid ultrasound imaging fused with conventional risk factors can provide better CVD/stroke risk prediction than conventional CVD risk calculators (CCVRC). Carotid ultrasound and coronary angiography were performed on 500 participants. Stenosis...
Source: The International Journal of Cardiovascular Imaging - November 12, 2020 Category: Radiology Source Type: research

Difference of vascular healing between bioabsorbable-polymer and durable-polymer new generation drug-eluting stents: an optical coherence tomographic analysis
This study compared the vascular healing at 8-month follow-up by optical coherence tomography (OCT) between 4 different kinds of new generation drug-eluting stents (DESs). We enrolled 112 patients (112 de novo lesions) who underwent OCT guided percutaneous coronary intervention with 4 kinds of new generation DESs including bioabsorbable-polymer everolimus-eluting stents (BP-EESs), bioabsorbable-polymer sirolimus-eluting stents (BP-SESs), durable-polymer everolimus-eluting stents (DP-EESs), and durable-polymer zotarolimus-eluting stents (DP-ZESs) and an 8-month follow-up angiogram and OCT were performed between July 2016 an...
Source: The International Journal of Cardiovascular Imaging - November 9, 2020 Category: Radiology Source Type: research

Appropriate device selection for transcatheter atrial septal defect closure using three-dimensional transesophageal echocardiography
AbstractDetail morphological evaluation for ASD is essential to achieve successful transcatheter closure. Three-dimensional transesophageal echocardiography (3D-TEE) is emerging, but few studies have comprehensively verified the usefulness of 3D-TEE. We divided 329 patients who underwent transcatheter ASD closure at our university hospital into 157 in the Conventional group evaluated with 2-dimensional transesophageal echocardiography and balloon sizing (BS), and 172 in the 3D-TEE group evaluated with 3D-TEE additionally. We assessed usefulness of 3D-TEE and consider appropriate device selection procedure. Overall, the per...
Source: The International Journal of Cardiovascular Imaging - November 5, 2020 Category: Radiology Source Type: research

Feasibility of morphological assessment of coronary artery calcification with electrocardiography-gated non-contrast computed tomography: a comparative study with optical coherence tomography
AbstractTo investigate the feasibility of pre-procedural morphological assessment of coronary artery calcification in severely calcified lesions with electrocardiography (ECG)-gated non-contrast computed tomography (CT). Severely calcified coronary arteries in patients who underwent ECG-gated non-contrast CT prior to optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) were studied retrospectively. CT and OCT data were co-registered by marking landmark structures such as side branches and reviewed side by side with cross-sectional images. The maximum calcium angle (MCA) and presence of nodular...
Source: The International Journal of Cardiovascular Imaging - November 5, 2020 Category: Radiology Source Type: research

Persistent pulmonary vein thrombosis
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 5, 2020 Category: Radiology Source Type: research

Epicardial adipose tissue characteristics and CT high-risk plaque features: correlation with coronary thin-cap fibroatheroma determined by intravascular ultrasound
AbstractTo investigate the correlation of epicardial adipose tissue (EAT) characteristics and high-risk plaque features characterized by coronary CT angiography (CCTA) for identifying the presence of thin-cap fibroatheroma (TCFA). Patients who underwent both CCTA and intravascular ultrasound (IVUS) within 4  weeks were retrospectively included. CT-derived quantitative and qualitative parameters, including diameter stenosis, low attenuation plaque (LAP), napkin-ring sign (NRS), positive remodeling and spotty calcification, were recorded. EAT volume and density were also measured. TCFA lesions and non-T CFA lesions were...
Source: The International Journal of Cardiovascular Imaging - October 17, 2020 Category: Radiology Source Type: research

Assessment of left ventricular systolic function in hypertrophic cardiomyopathy patients with myocardial injury: a study based on layer-specific speckle tracking echocardiaography
AbstractWe conducted this study to investigate left ventricle (LV) systolic function in endocardial, mid-myocardial, and epicardial layers by two-dimensional (2D) speckle tracking echocardiography (STE) in hypertrophic cardiomyopathy (HCM) patients with myocardial injury indexed by elevated serum cardiac troponin I (cTnI). Twenty-nine HCM patients with myocardial injury, thirty-five HCM patients without myocardial injury, and ninty-one healthy controls were enrolled in this study. Serum cTnI  >  0.026 ng/mL was defined as myocardial injury. LV longitudinal and circumferential strain (LS and CS) were a...
Source: The International Journal of Cardiovascular Imaging - October 17, 2020 Category: Radiology Source Type: research

Delayed isolated peri-myocarditis in a Covid-19 patient with respiratory symptoms but without lung involvement
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 17, 2020 Category: Radiology Source Type: research

Is an ischemic origin in MINOCA patients predictable?
This study sought to identify parameters that could guide towards an ischemic origin in patients hospitalized for myocardial infarction (MI) with  non-obstructive coronary arteries (MINOCA). MINOCA is challenging in clinical practice, as the pathophysiology is multifaceted. A total of 135 patients with MINOCA who underwent cardiovascular magnetic resonance imaging (CMR) in a single tertiary University Hospital, were retrospectively included . The study cohort was classified into 4 groups according to the CMR diagnosis (i.e., myocarditis, myocardial infarction, Takotsubo cardiomyopathy, normal or uncommo...
Source: The International Journal of Cardiovascular Imaging - October 17, 2020 Category: Radiology Source Type: research

Indexed left ventricular mass to QRS voltage ratio is associated with heart failure hospitalizations in patients with cardiac amyloidosis
AbstractIn cardiac amyloidosis (CA), amyloid infiltration results in increased left ventricular (LV) mass disproportionate to electrocardiographic (EKG) voltage. We assessed the relationship between LV mass –voltage ratio with subsequent heart failure hospitalization (HHF) and mortality in CA. Patients with confirmed CA and comprehensive cardiovascular magnetic resonance (CMR) and EKG exams were included. CMR-derived LV mass was indexed to body surface area. EKG voltage was assessed using Sokolow, Co rnell, and Limb–voltage criteria. The optimal LV mass–voltage ratio for predicting outcomes was determined...
Source: The International Journal of Cardiovascular Imaging - October 17, 2020 Category: Radiology Source Type: research

Dynamic handgrip exercise for the evaluation of mitral valve regurgitation: an echocardiographic study to identify exertion induced severe mitral regurgitation
This study aims to evaluate this effect and the possible role of HG in the echocardiographic evaluation of MR. 722 patients with MR were included (18% primary, 82% secondary disease). We calculated effective regurgitant orifice area (EROA) and regurgitant volume (RVOL) at rest and during dynamic HG. Increase in MR was defined as any increase in EROA or RVOL. We analyzed the data to identify possible associations between clinical or echocardiographic parameters and the effect of HG on MR. MR increased during dynamic HG in 390 of 722 patients (54%) ( ∆EROA = 25%, ∆RVOL = 27%). Increase of regu...
Source: The International Journal of Cardiovascular Imaging - October 16, 2020 Category: Radiology Source Type: research

Feasibility and functional correlates of left atrial volume changes during stress echocardiography in chronic coronary syndromes
AbstractAn enlarged left atrial volume index (LAVI) at rest mirrors increased LA pressure and/or impairment of LA function. A cardiovascular stress may acutely modify left atrial volume (LAV) within minutes. Aim of this study was to assess the feasibility and functional correlates of LAV-stress echocardiography (SE) Out of 514 subjects referred to 10 quality-controlled labs, LAV-SE was completed in 490 (359 male, age 67  ± 12 years) with suspected or known chronic coronary syndromes (n = 462) or asymptomatic controls (n = 28). The utilized stress was exercise in 177, va...
Source: The International Journal of Cardiovascular Imaging - October 15, 2020 Category: Radiology Source Type: research

Feasibility of 18 FDG PET in the cardiac inflammation
AbstractThe aim of the study was to assess the feasibility of18FDG PET in cardiac inflammation with a particular focus on the delayed scan. Thirty-five consecutive18FDG PET scans of patients with suspected or confirmed cardiac inflammation were retrospectively reviewed. The patients were referred for PET because of endocarditis (n  = 16) or sarcoidosis (n = 19). Among them four patients had two consecutive for follow up and treatment control (two patients with sarcoidosis, two with endocarditis). In all of the cases a standard head to mid-thigh scan was performed 45–60 min after18FDG ...
Source: The International Journal of Cardiovascular Imaging - October 15, 2020 Category: Radiology Source Type: research

Subclinical ventricular dysfunction in rheumatoid arthritis
AbstractPatients with rheumatoid arthritis (RA) are at higher risk for having underdiagnosed heart failure, however there are no recommendations regarding echocardiographic screening. We aimed to determine the prevalence of subclinical ventricular dysfunction in RA applying current echocardiographic guidelines, its association with patients ’ characteristics, biomarkers and prognostic parameters and compare the 2016 guidelines to the recommendations from 2009. Prospective study of RA patients without known heart disease, categorized as preserved ventricular function (PVF), systolic dysfunction (SD), isolated diastoli...
Source: The International Journal of Cardiovascular Imaging - October 14, 2020 Category: Radiology Source Type: research

Cardiac magnetic resonance imaging for the detection of myocardial involvement in granulomatosis with polyangiitis
AbstractThe prevalence of undiagnosed cardiac involvement in granulomatosis with polyangiitis (GPA) is unknown. In this prospective study we investigated the utility of cardiovascular magnetic resonance (CMR) to identify myocardial abnormalities in GPA and their correlation with disease phenotype. Twenty-six patients with GPA and no cardiovascular disease or diabetes mellitus underwent contrast-enhanced CMR, including late gadolinium-enhancement (LGE), T1-mapping for native T1 and extra-cellular volume (ECV) quantification for assessment of myocardial fibrosis, cine imaging and tissue tagging for assessment of left ventric...
Source: The International Journal of Cardiovascular Imaging - October 14, 2020 Category: Radiology Source Type: research

Myocardial adaptation as assessed by speckle tracking echocardiography after isolated mitral valve surgery for primary mitral regurgitation
AbstractThe risk of left ventricular (LV) and right ventricular (RV) maladaptation after surgery for isolated primary mitral regurgitation (PMR) is poorly defined. We aimed to evaluate LV and RV contractile function using speckle-tracking analysis alongside with quantification of exercise tolerance in patients with PMR after mitral valve surgery. All consecutive patients with symptomatic PMR undergoing mitral valve surgery between July 2015 and May 2017 were prospectively enrolled. Sequential echocardiographic studies along with clinical assessment were performed before and three months after surgery. Mean age in 138 patie...
Source: The International Journal of Cardiovascular Imaging - October 13, 2020 Category: Radiology Source Type: research

Assessment of biatrial function in clinically well pediatric bicaval heart transplantation patients by three-dimensional echocardiography
AbstractAtrial size and function are closely correlated with atrial contributions to cardiovascular performance. Therefore, in this study, we aimed to assess atrial size and function in pediatric heart transplantation (HTx) patients using three-dimensional echocardiography (3DE). We enrolled 33 clinically well pediatric HTx patients and 33 healthy controls with a similar distribution of sex and age to the HTx patients. All patients underwent two-dimensional echocardiography (2DE) and 3DE. 2DE- and 3DE-derived biatrial maximal volume  (Vmax), minimal volume (Vmin), ejection volume (EV), ejection fraction (EF), volume b...
Source: The International Journal of Cardiovascular Imaging - October 13, 2020 Category: Radiology Source Type: research

Transesophageal echocardiography in swine: evaluation of left and right ventricular structure, function and myocardial work
This study aimed to determine standard left (LV) and right ventricular (RV) transesophageal echocardiographic (TEE) measurements in swine. Additionally, global myocardial work index (GWI) was estimated using pressure-strain loops (PSL). A comprehensive TEE examination was conducted in ten anesthetized, intubated and mechanically ventilated healthy female German landrace swine, weighing 44 to 57 kg. For GWI calculation, we performed LV and RV segmental strain analysis and used invasively measured LV and RV pressure to obtain PSL. The GWI and further myocardial work indices were calculated from the area of the PSL using comm...
Source: The International Journal of Cardiovascular Imaging - October 13, 2020 Category: Radiology Source Type: research

Favorable changes of left ventricular function in the circumferential direction following transcatheter atrial septal defect closure: a strain imaging study
AbstractTo clarify the impact on left ventricular (LV) function of percutaneous atrial septal defect (ASD) closure in adult patients.  Echocardiograms of 46 patients (52 ± 18 years) who underwent ASD closure with a significant left-to-right shunt obtained before and 1 month after the procedure were retrospectively analyzed. Functional parameters were obtained by 2-dimensional speckle-tracking imaging. Global longitudinal st rain and strain rate at early diastole (SRe) was calculated from the three standard apical views, while circumferential and radial parameters were calculated from basal, m...
Source: The International Journal of Cardiovascular Imaging - October 12, 2020 Category: Radiology Source Type: research

Left ventricular mechanics in patients with hematological malignancies before initiation of chemo- and radiotherapy
Abstract Objective We sought to investigate left ventricular (LV) structure, function and mechanics in the patients with leukemia and lymphoma before initiation of chemotherapy, as well as the relationship between hematological malignancies and reduced LV longitudinal strain. Methods This retrospective investigation included 71 patients with leukemia and lymphoma before chemotherapy and 36 healthy controls. All participants underwent echocardiographic examination before initiation of chemotherapy and radiotherapy. Results LV global longitudinal strain ( − 20.2 ± 1.7% vs. &minus...
Source: The International Journal of Cardiovascular Imaging - October 12, 2020 Category: Radiology Source Type: research

Normative values of cardiac chamber dimensions and global longitudinal strain in Indians: the Indian Normative Data of Echocardiography Analyzed (INDEA) study
AbstractEthnic-specific normal reference ranges for various echocardiographic measurements are essential for accurate diagnostic interpretation and clinical decision-making. Unfortunately, such normative data for Indians is lacking. A total of 880 healthy volunteers (mean age 39.7  ± 12.3 years, 63.8% men) from six centers across different regions of India were enrolled in this study. Comprehensive transthoracic echocardiographic study was performed in all subjects, in accordance with the existing guideline recommendations. Cardiac chamber dimensions [Left ventricular (L V) end-diastolic diameter and v...
Source: The International Journal of Cardiovascular Imaging - October 12, 2020 Category: Radiology Source Type: research

Quantitative perfusion-CMR is significantly influenced by the placement of the arterial input function
AbstractThe aim of this study is to provide a systematic assessment of the influence of the position on the arterial input function (AIF) for perfusion quantification. In 39 patients with a wide range of left ventricular function the AIF was determined using a diluted contrast bolus of a cardiac magnetic resonance imaging in three left ventricular levels (basal, mid, apex) as well as aortic sinus (AoS). Time to peak signal intensities, baseline corrected peak signal intensity and upslopes were determined and compared to those obtained in the AoS. The error induced by sampling the AIF in a position different to the AoS was ...
Source: The International Journal of Cardiovascular Imaging - October 12, 2020 Category: Radiology Source Type: research

Quantitative evaluation of coronary artery visibility on CT angiography in Kawasaki disease: young vs. old children
AbstractCoronary artery visibility on coronary CT angiography has rarely been investigated in young children with Kawasaki disease. This retrospective study was performed to quantitatively evaluate and compare coronary artery visibility with sufficient quality to measure it on coronary CT angiography among younger and older children with Kawasaki disease. Seventy-eight consecutive children with Kawasaki disease who underwent coronary CT angiography were divided into two groups: group 1 (age  ≤ 6 years; n = 37) and group 2 (age >  6 years and 
Source: The International Journal of Cardiovascular Imaging - October 12, 2020 Category: Radiology Source Type: research

Clinical implication of QFR in patients with ST-segment elevation myocardial infarction after drug-eluting stent implantation
AbstractThe feasibility and prognostic value of quantitative flow ratio (QFR) after percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) patients have not been assessed. The aim of this study was to investigate the prognostic utility of post-PCI QFR to predict outcomes in STEMI and determine the influence of functional results, in both culprit and nonculprit lesions, after PCI. Patients undergoing PCI of culprit lesions and receiving staged procedures of nonculprit lesions after 7  days were enrolled from 2 centers and underwent post-PCI QFR. The primary outcome was the vessel...
Source: The International Journal of Cardiovascular Imaging - October 12, 2020 Category: Radiology Source Type: research

Validity of visual assessment of aortic valve morphology in patients with aortic stenosis using two-dimensional echocardiography
AbstractThe diagnostic value of a visual assessment of aortic valve (AV) morphology for grading aortic stenosis (AS) remains unclear. A visual score (VS) for assessing the AV was developed and its reliability with respect to Doppler measurements and the calcium score (ctCS) derived by multislice computed tomography was evaluated. 99 Patients with AS of various severity and 38 patients without AS were included in the analysis. Echocardiographic studies were evaluated using the new VS which includes echogenicity, thickening, localization of lesions and leaflet mobility, with a total score ranging from 0 to 11. The associatio...
Source: The International Journal of Cardiovascular Imaging - October 11, 2020 Category: Radiology Source Type: research

Does heart failure with mid-range ejection fraction resemble heart failure with preserved ejection fraction?
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 11, 2020 Category: Radiology Source Type: research