Morphologies and prognostic significance of left ventricular volume/time curves with cardiac magnetic resonance in patients with non-ischaemic heart failure and left bundle branch block
AbstractPatients with non-ischaemic systolic heart failure (HF) and left bundle branch block (LBBB) can display a wide or narrow pattern (WP/NP) of the systolic phase of the left ventricular (LV) volume/time (V/t) curve in cardiac magnetic resonance (CMR). The clinical and prognostic significance of these patterns is unknown. Consecutive patients with non-ischaemic HF, LV ejection fraction  
Source: The International Journal of Cardiovascular Imaging - February 26, 2021 Category: Radiology Source Type: research

Echocardiographic assessment of left ventricular filling pressure in patients with acute ST elevation myocardial infarction: an invasive validation study
AbstractBackgrounds Assessment of left ventricular filling pressure (LVFP) is of clinical importance in patients with ST elevation myocardial infarction (STEMI). Although several echocardiographic parameters are recommended for the assessment of LVFP, validation of these parameters in patients with STEMI is missing. We aimed to investigate the clinical utility of these parameters in acute settings. Methods: We prospectively included consecutive patients with STEMI. LV end-diastolic pressure (LVEDP) was measured following primary PCI and echocardiographic examination was performed within 24 hours. Mean left atrial pressure ...
Source: The International Journal of Cardiovascular Imaging - February 23, 2021 Category: Radiology Source Type: research

Diagnostic value of echocardiography in paracardiac cystic lesions: 43 cases from one single medical center
AbstractParacardial cystic lesions (PCLs) are rare, benign lesions and may occur in any part surrounding the heart. It covers a variety of pathological types, including pericardial cysts, thymic cysts, bronchogenic cysts and so on. The aim of this study was to summarize the diagnostic value of echocardiography in different pathological types of the PCLs. Echocardiographic features of 43 consecutive PCL patients treated at the Union Hospital from January 2002 to December 2017 were compared and analyzed with their surgical and pathological findings retrospectively. The PCLs included 19 pericardial cysts, 12 thymic cysts, 7 b...
Source: The International Journal of Cardiovascular Imaging - February 23, 2021 Category: Radiology Source Type: research

Impaired left atrial function in clinically well heart transplant patients
This study evaluated LA function in 112 clinically well HT patients and 40 healthy controls. Clinical data included recipient age at HT, donor age, ischemia time, left ventricular function, and biochemical indicators. Atrial deformation and volume indices were measured with two-dimensional and three-dimensional speckle-tracking echocardiography, respectively. Components of phasic atrial function were calculated and correlations to clinical variables were explored. Compared with controls, HT patients had worse LA reservoir, conduit, and pump function. LA reservoir function of the bicaval group was better than the biatrial g...
Source: The International Journal of Cardiovascular Imaging - February 23, 2021 Category: Radiology Source Type: research

The heart as a spring, the measurement of myocardial bounce to assess left ventricular function on cardiac MR
AbstractLittle has been reported on the left ventricular myocardial distension (bounce) and its utility to assess cardiac function. The purpose of this study is to determine whether myocardial bounce at end diastole is reproducibly visualized by blinded observers and to determine whether it corresponds to systolic and diastolic function. 144 Consecutive cardiac MR exams between September and December 2017 were selected for analysis. The bounce was graded by two blinded observers, and the change in LV diameter pre and post bounce was measured. The bounce was defined as the rapid change in LV volume that occurs at the end of...
Source: The International Journal of Cardiovascular Imaging - February 23, 2021 Category: Radiology Source Type: research

Clinical impact of pre-kidney transplant pulmonary hypertension on post-transplant outcomes
AbstractOutcomes of kidney transplant (KT) patients with pre-transplant pulmonary hypertension (PH) are poorly understood. PH patients are often considered high risk and excluded from KT. We investigated the association of pre-transplant PH with KT recipient ’s outcomes. A single-center, retrospective study that reviewed all patients transplanted from 2010 to 2016, who had a transthoracic echocardiogram (TTE) before KT and at least one TTE post-KT. The TTE closest to the KT was used for analyses. PH is defined as pulmonary artery systolic pressure (PA SP) ≥ 40 mm Hg. Of 204 patients, 61 had PASP...
Source: The International Journal of Cardiovascular Imaging - February 22, 2021 Category: Radiology Source Type: research

Quantification of regurgitation in mitral valve prolapse with automated real time echocardiographic 3D proximal isovelocity surface area: multimodality consistency and role of eccentricity index
AbstractThree-dimensional transthoracic echocardiography (3D-TTE) provides a semi-automated proximal isovelocity surface area method (3D-PISA) to obtain quantitative parameters. Data assessing regurgitation severity in mitral valve prolapse (MVP) are scarce, so we assessed the 3D-PISA method compared with 2D-PISA and cardiovascular magnetic resonance (CMR) and the role of an eccentricity index. We evaluated the 3D-PISA method for assessing MR in 54 patients with MVP (57  ± 14 years; 42 men; 12 mild/mild-moderate; 12 moderate-severe; and 30 severe MR). Role of an asymmetric (i.e. eccentricity index...
Source: The International Journal of Cardiovascular Imaging - February 22, 2021 Category: Radiology Source Type: research

The corrected left ventricular ejection fraction: a potential new measure of ventricular function
AbstractLeft ventricular ejection fraction (LVEF) has a limited role in predicting outlook in heart diseases including heart failure. We quantified the independent geometric factors that determine LVEF using cardiac MRI and sought to provide an improved measure of ventricular function by adjusting for such independent variables. A mathematical model was used to analyse the independent effects of structural variables and myocardial shortening on LVEF. These results informed analysis of cardiac MRI data from 183 patients (53 idiopathic dilated cardiomyopathy (DCM), 36 amyloidosis, 55 hypertensives and 39 healthy controls). L...
Source: The International Journal of Cardiovascular Imaging - February 22, 2021 Category: Radiology Source Type: research

IVUS-guided decision-making in acute coronary syndrome after resuscitated cardiac arrest
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - February 22, 2021 Category: Radiology Source Type: research

Impact of surgical aortic valve replacement on global and regional longitudinal strain across four flow gradient patterns of severe aortic stenosis
AbstractTo evaluate the impact of surgical aortic valve replacement (SAVR) on global (GLS) and regional longitudinal strain (RLS) across four flow-gradient patterns of severe aortic stenosis (AS) 3  months after surgery. A total of 103 patients with severe AS (aortic valve area 35  mL/m2 vs. ≤35 mL/m2) and mean transaortic gradients (>40 mmhg vs. ≤40 mmhg): normal-flow, high gradient (NF/HG); low-flow, high gradient (LF/HG); normal-flow, low gradient (NF/LG); low-flow, low gradient (LF/LG). Strain analysis comprised GLS and RLS at a basal (BLS), mid-ventricular (MLS) and apical lev...
Source: The International Journal of Cardiovascular Imaging - February 19, 2021 Category: Radiology Source Type: research

A deep learning approach with temporal consistency for automatic myocardial segmentation of quantitative myocardial contrast echocardiography
AbstractQuantitative myocardial contrast echocardiography (MCE) has been proved to be valuable in detecting myocardial ischemia. During quantitative MCE analysis, myocardial segmentation is a critical step in determining accurate region of interests (ROIs). However, traditional myocardial segmentation mainly relies on manual tracing of myocardial contours, which is time-consuming and laborious. To solve this problem, we propose a fully automatic myocardial segmentation framework that can segment myocardial regions in MCE accurately without human intervention. A total of 100 patients ’ MCE sequences were divided into ...
Source: The International Journal of Cardiovascular Imaging - February 17, 2021 Category: Radiology Source Type: research

Myocardial work is associated with significant left ventricular myocardial fibrosis in patients with hypertrophic cardiomyopathy
AbstractLate gadolinium enhancement on cardiac magnetic resonance adds prognostic information in patients with hypertrophic cardiomyopathy. Whether Myocardial work, a new parameter on transthoracic echocardiographic, can be associated with significant fibrosis in hypertrophic cardiomyopathy patients is unknown. In a single-centre prospective evaluation of hypertrophic cardiomyopathy patients in whom transthoracic echocardiographic and cardiac magnetic resonance were performed, Myocardial work and related indices were calculated from global longitudinal strain and from estimated left ventricular pressure curves. The extent ...
Source: The International Journal of Cardiovascular Imaging - February 17, 2021 Category: Radiology Source Type: research

Comparable neointimal healing in patients with stable coronary lesions and acute coronary syndrome: 3-month optical coherence tomography analysis
AbstractWe aimed to assess a possible difference of the neointimal coverage status and its quality after implantation of the current-generation metallic stents in patients with acute coronary syndrome (ACS) vs. stable coronary lesions (non-ACS). We comprehensively analyzed three prospective single-center observational studies RESTORE (UMIN000033009), HEAL-BioFreedom (UMIN000029692), and HEAL-BioFreedom ACS (UMIN000034769). All patients who received successful optical coherence tomography (OCT) examination at planned 3-month follow-up after stent implantation were analyzed. Study population was divided into two groups, ACS ...
Source: The International Journal of Cardiovascular Imaging - February 16, 2021 Category: Radiology Source Type: research

Deep-learning-based cardiac amyloidosis classification from early acquired pet images
In conclusion, the proposed CAclassNet model seems very promising as an aid for the clinician in the diagnosis of CA from cardiac [ 18F]-Florbetaben PET images acquired a few minutes after the injection. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - February 16, 2021 Category: Radiology Source Type: research

Importance of left atrial mechanical function as a predictor of atrial fibrillation risk following cardiac surgery
AbstractPostoperative atrial fibrillation (POAF) after cardiac surgery is a major health problem that is associated with a significant financial burden and increased early morbidity and mortality. We investigated the accuracy of new echocardiographic derived indices to predict patients at higher risk of developing POAF. 84 consecutive patients (age 57.9  ± 6.9, 32% female) hospitalized for isolated CABG underwent comprehensive echocardiographic evaluation before surgery. Left atrial (LA) function was quantified through the assessment of phasic LA volumes to calculate LATEF. Speckle tracking echocardiog...
Source: The International Journal of Cardiovascular Imaging - February 16, 2021 Category: Radiology Source Type: research

A deep learning methodology for the automated detection of end-diastolic frames in intravascular ultrasound images
AbstractCoronary luminal dimensions change during the cardiac cycle. However, contemporary volumetric intravascular ultrasound (IVUS) analysis is performed in non-gated images as existing methods to acquire gated or to retrospectively gate IVUS images have failed to dominate in research. We developed a novel deep learning (DL)-methodology for end-diastolic frame detection in IVUS and compared its efficacy against expert analysts and a previously established methodology using electrocardiographic (ECG)-estimations as reference standard. Near-infrared spectroscopy-IVUS (NIRS-IVUS) data were prospectively acquired from 20 cor...
Source: The International Journal of Cardiovascular Imaging - February 15, 2021 Category: Radiology Source Type: research

Parkes-Weber Syndrome and double orifice atrial septal defect as a combined rare cause of severe pulmonary hypertension
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - February 15, 2021 Category: Radiology Source Type: research

Added value of cardiovascular calcifications for prediction of recurrent cardiovascular events and cardiovascular interventions in patients with established cardiovascular disease
AbstractThe purpose is to investigate the added prognostic value of coronary artery calcium (CAC), thoracic aortic calcium (TAC), and heart valve calcium scores for prediction of a combined endpoint of recurrent major cardiovascular events and cardiovascular interventions (MACE  +) in patients with established cardiovascular disease (CVD). In total, 567 patients with established CVD enrolled in a substudy of the UCC-SMART cohort, entailing cardiovascular CT imaging and calcium scoring, were studied. Five Cox proportional hazards models for prediction of 4-year risk of MA CE + were developed; traditiona...
Source: The International Journal of Cardiovascular Imaging - February 12, 2021 Category: Radiology Source Type: research

A comparison of 8 and 16 frames gated SPECT imaging for determination of left ventricular volumes and ejection fraction: effects of gender and myocardial counts
AbstractIn myocardial gated SPECT imaging each cardiac cycle is divided into 8 or 16 temporal frames and the cause of the difference between 8 and 16 frames is not specified exactly. The aim of this study was to investigate the effect of myocardial detector counts and gender on the difference between 8 and 16 frames and also to compare the LVEF obtained by 8 and 16 frames with echocardiography. The study population included 84 patients who underwent gated SPECT imaging. Left ventricular parameters were assessed on 8 and 16 frames gated SPECT. LVEF was also measured with two-dimensional echocardiography within 5 –10&n...
Source: The International Journal of Cardiovascular Imaging - February 11, 2021 Category: Radiology Source Type: research

A novel predictive model for late recurrence after catheter ablation for atrial fibrillation using left appendage volume measured by cardiac computed tomography
AbstractLarger left atrial appendage (LAA) volume is associated with a higher risk of late recurrence (LR) in patients undergoing radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). However, it is unclear whether LAA volume predicts LR, independent of established risk factors. We sought to evaluate the value of LAA volume in predicting LR after RFCA for AF and to develop a score prediction model including LAA volume for these patients. We retrospectively studied 992 patients who underwent RFCA for AF and cardiac computed tomography before RFCA at a single center. At 3 years after RFCA, 362 patients (3...
Source: The International Journal of Cardiovascular Imaging - February 10, 2021 Category: Radiology Source Type: research

Regional myocardial function at preclinical disease stage of hypertrophic cardiomyopathy in female gene variant carriers
AbstractWe recently showed more severe diastolic dysfunction at the time of myectomy in female compared to male patients with obstructive hypertrophic cardiomyopathy. Early recognition of aberrant cardiac contracility using cardiovascular magnetic resonance (CMR) imaging may identify women at risk of cardiac dysfunction. To define myocardial function at an early disease stage, we studied regional cardiac function using CMR imaging with tissue tagging in asymptomatic female gene variant carriers. CMR imaging with tissue tagging was done in 13MYBPC3, 11MYH7 and 6TNNT2 gene carriers and 16 age-matched controls. Regional peak ...
Source: The International Journal of Cardiovascular Imaging - February 9, 2021 Category: Radiology Source Type: research

Contemporary use of cardiac imaging for COVID-19 patients: a three center experience defining a potential role for cardiac MRI
AbstractThe pandemic of coronavirus disease 2019 (COVID-19) secondary to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has bestowed an unprecedented challenge upon us, resulting in an international public health emergency. COVID-19 has already resulted in>  1,600,000 deaths worldwide and the fear of a global economic collapse. SARS-CoV-2 is notorious for causing acute respiratory distress syndrome, however emerging literature suggests various dreaded cardiac manifestations associated with high mortality. The mechanism of myocardial damage in COVID-1 9 is unclear but thought to be multifac...
Source: The International Journal of Cardiovascular Imaging - February 9, 2021 Category: Radiology Source Type: research

AL cardiac amyloidosis with widespread myocardial infiltration in the absence of hyperenhancement on conventional magnitude late gadolinium enhancement cardiovascular magnetic resonance imaging
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - February 9, 2021 Category: Radiology Source Type: research

The effect of moderate and severe COVID-19 pneumonia on short-term right ventricular functions: a prospective observational single pandemic center analysis
Abstract It has been reported that myocardial damage and heart failure are more common in COVID-19 patients with severe symptoms. The aim of our study was to measure the right ventricular functions of COVID-19 patients 30  days after their discharge, and compare them to the right ventricular functions of healthy volunteers. Fifty one patients with COVID-19 and 32 healthy volunteers who underwent echocardiographic examinations were enrolled in our study. 29 patients were treated for severe and 22 patients were treate d for moderate COVID-19 pneumonia. The study was conducted prospectively, in a single center, between 1...
Source: The International Journal of Cardiovascular Imaging - February 8, 2021 Category: Radiology Source Type: research

Prognostic significance of cardiac magnetic resonance-based markers in patients with hypertrophic cardiomyopathy
AbstractThe prognosis of patients with hypertrophic cardiomyopathy (HCM) varies greatly. Cardiac magnetic resonance (CMR) is the gold standard method for assessing left ventricular (LV) mass and volumes. Myocardial fibrosis can be noninvasively detected using CMR. Moreover, feature-tracking (FT) strain analysis provides information about LV deformation. We aimed to investigate the prognostic significance of standard CMR parameters, myocardial fibrosis, and LV strain parameters in HCM patients. We investigated 187 HCM patients who underwent CMR with late gadolinium enhancement and were followed up. LV mass (LVM) was evaluat...
Source: The International Journal of Cardiovascular Imaging - February 8, 2021 Category: Radiology Source Type: research

Cardiac magnetic resonance in patients with ARVC and family members: the potential role of native T1 mapping
This study explored the diagnostic role of myocardial native T1 mapping in patients with ARVC and their first-degree relatives. Thirty ARVC patients (47% males, mean age 45  ± 27 years) and 59 first-degree relatives not meeting diagnostic criteria underwent CMR with native T1 mapping. C MR was abnormal in 26 (87%) patients with ARVC. The right ventricle was affected in isolation in 13 (43%) patients. Prior to T1 mapping assessment, 2 (7%) patients exhibited isola ted LV involvement and 11 (36%) patients showed features of biventricular disease. Left ventricular involvement was manifest as detectab...
Source: The International Journal of Cardiovascular Imaging - February 7, 2021 Category: Radiology Source Type: research

The effect of spironolactone on diastolic function in haemodialysis patients
AbstractHeart failure with preserved ejection fraction (HFpEF) is highly prevalent in patients on maintenance haemodialysis (HD) and lacks effective treatment. We investigated the effect of spironolactone on cardiac structure and function with a specific focus on diastolic function parameters. The MiREnDa trial examined the effect of 50  mg spironolactone once daily versus placebo on left ventricular mass index (LVMi) among 97 HD patients during 40 weeks of treatment. In this echocardiographic substudy, diastolic function was assessed using predefined structural and functional parameters including E/e’. Cha...
Source: The International Journal of Cardiovascular Imaging - February 5, 2021 Category: Radiology Source Type: research

Atrial performance in healthy subjects following high altitude exposure at 4100  m: 2D speckle-tracking strain analysis
In conclusion, short-term HA exposure of healthy individuals impairs bi-atrial performance, mostly observed in RA. Especially, atrial contractile function decreases in RA rather than LA, which seems not to compensate for decreased ventricular filling after HA exposure. Our findings may provide a novel evidence for right-sided heart dysfunction to HA exposure. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - February 5, 2021 Category: Radiology Source Type: research

Use of radiomics to differentiate left atrial appendage thrombi and mixing artifacts on single-phase CT angiography
AbstractTo assess if radiomics can differentiate left atrial appendage (LAA) contrast-mixing artifacts and thrombi on early-phase CT angiography without the need for late-phase images. Our study included 111 patients who underwent early- and late-phase, contrast-enhanced cardiac CT. Of these, 79 patients had LAA filling defects from thrombus (n  = 46, mean age: 72  ±  12 years, M:F 26:20) or contrast-mixing artifact (n = 33, mean age: 71  ±  13 years, M:F 21:12) on early-contrast-enhanced phase. The remaining 32 patients (me...
Source: The International Journal of Cardiovascular Imaging - February 5, 2021 Category: Radiology Source Type: research

Incremental prognostic role of left atrial reservoir strain in asymptomatic patients with moderate aortic stenosis
AbstractLeft atrial (LA) mechanics assessed by two-dimensional speckle tracking echocardiography (2D-STE) have not been extensively studied and clearly characterized in patients with moderate aortic stenosis (AS). Accordingly, we aimed to evaluate the usefulness of LA reservoir strain for risk stratification of asymptomatic patients with moderate AS. This retrospective study included all consecutive asymptomatic patients with moderate AS who underwent transthoracic echocardiography implemented with 2D-STE analysis of LA myocardial strain and strain rate indices at our Institution, between February 2011 and September 2019. ...
Source: The International Journal of Cardiovascular Imaging - February 5, 2021 Category: Radiology Source Type: research

Acute recoordination rather than functional hemodynamic improvement determines reverse remodelling by cardiac resynchronisation therapy
AbstractPurpose: Cardiac resynchronisation therapy (CRT) improves left ventricular (LV) function acutely, with further improvements and reverse remodelling during chronic CRT. The current study investigated the relation between acute improvement of LV systolic function, acute mechanical recoordination, and long-term reverse remodelling after CRT.Methods: In 35 patients, LV speckle tracking longitudinal strain, LV volumes& ejection fraction (LVEF) were assessed by echocardiography before, acutely within three days, and 6  months after CRT. A subgroup of 25 patients underwent invasive assessment of the maximal rate ...
Source: The International Journal of Cardiovascular Imaging - February 5, 2021 Category: Radiology Source Type: research

Fluoroless catheter ablation of accessory pathways in adult and pediatric patients: a single centre experience
AbstractCatheter radio-frequency ablation (RFA) and cryo-ablation (CRA) procedures are an effective and safe treatment options for adult and pediatric patients with accessory pathway (AP) mediated tachycardias. Non-fluoroscopic techniques during catheter ablation (CA) procedures reduce potentially harmful effects of radiation. Our aim was to investigate the efficacy and safety of completely fluoroless RFA and CRA procedures in pediatric and adult patients with APs. Consecutive patients with AP-related tachycardia and high risk asymptomatic ventricular pre-excitation were assessed in retrospective analysis. Three-dimensiona...
Source: The International Journal of Cardiovascular Imaging - February 2, 2021 Category: Radiology Source Type: research

A prediction model of simple echocardiographic variables to screen for potentially correctable shunts in adult patients with pulmonary arterial hypertension associated with atrial septal defects: a cross-sectional study
AbstractDuring the routine follow-up of adult patients with pulmonary arterial hypertension associated with atrial septal defects (ASD-PAH), the suitability of shunt closure depends on the invasive right heart catheterization (RHC). It is difficult to grasp the timing of RHC shunt closure for moderate-severe PAH. This retrospective cross-sectional study was designed to investigate which echocardiographic variables are related to pulmonary vascular resistance (PVR) in adult ASD-PAH patients and propose a method using echocardiographic variables to screen for patients where shunt closure is suitable. A total of 139 adult ASD...
Source: The International Journal of Cardiovascular Imaging - February 2, 2021 Category: Radiology Source Type: research

4D flow MRI left atrial kinetic energy in hypertrophic cardiomyopathy is associated with mitral regurgitation and left ventricular outflow tract obstruction
AbstractTo noninvasively assess left atrial (LA) kinetic energy (KE) in hypertrophic cardiomyopathy (HCM) patients using 4D flow MRI and evaluate coupling associations with mitral regurgitation (MR) and left ventricular outflow tract (LVOT) obstruction. Twenty-nine retrospectively identified patients with HCM underwent 4D flow MRI. MRI-estimated peak LVOT pressure gradient ( ∆PMRI) was used to classify patients into non-obstructive and obstructive HCM. Time-resolved volumetric LA kinetic energy (KELA) was computed throughout systole. Average systolic (KELA-avg) and peak systolic (KELA-peak) KELA were compared between non...
Source: The International Journal of Cardiovascular Imaging - February 1, 2021 Category: Radiology Source Type: research

Q waves in ischemic cardiomyopathy
This study sought to establish the determinants of Q waves in the absence of non-viable tissue and the diagnostic accuracy in this population. A retrospective study enrolling 487 consecutive patients (67.0 [57.4 – 75.4] years), with ICM, LVEF 
Source: The International Journal of Cardiovascular Imaging - January 31, 2021 Category: Radiology Source Type: research

CMR unveiling the cause of post CoVid-19 infection chest pain
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - January 28, 2021 Category: Radiology Source Type: research

The prognostic value of left atrial dyssynchrony measured by speckle tracking echocardiography in the general population
AbstractLA dyssynchrony is a predictor of cardiovascular morbidity in various patient populations. However, the prognostic value of LA dyssynchrony as evaluated by two-dimensional speckle tracking (2D-STE) in the general population is unknown. A cohort of 375 participants without atrial fibrillation (AF), ischemic heart disease (IHD), heart failure (HF) or previous ischemic stroke (IS) had an echocardiogram, including LA 2D-STE, performed. LA dyssynchrony was defined as the standard deviation of the time to peak regional LA reservoir strain values. The endpoints were all-cause mortality, a combined endpoint of AF and IS, a...
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Combining perfusion and angiography with a low-dose cardiac CT technique: a preliminary investigation in a swine model
The objective was to evaluate a low-dose cardiac CT technique that combines morphological and physiological assessment of CAD. The low-dose technique was evaluated in twelve swine, where three of the twelve had coronary balloon stenosis. The technique consisted of rest perfusion measurement combined with angiography followed by stress perfusion measurement, where the ratio of stress to rest was used to derive coronary flow reserve (CFR). The technique only required two volume scans for perfusion measurement in mL/min/g; hence, four volume scans were acquired in total; two for rest with angiography and two for stress. All r...
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Late presentation of ALCAPA syndrome: a rare cause of heart failure
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Maximum plaque height in carotid ultrasound predicts cardiovascular disease outcomes: a population-based validation study of the American society of echocardiography ’s grade II–III plaque characterization and protocol
AbstractThe presence of carotid arterial plaque by ultrasound enhances cardiovascular risk stratification beyond traditional risk factors. However, plaque quantification techniques require further outcomes-based investigation. The purpose of this study was to evaluate the utility of a focused carotid ultrasound protocol and novel plaque grading system developed by the American Society of Echocardiography (ASE). A retrospective analysis of 514 outpatients who were referred for coronary angiography between 2011 and 2014 was performed using a province-sponsored health database. All participants prospectively received a focuse...
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Characteristics of culprit lesion in patients with non-ST-elevation myocardial infarction and improvement of diagnostic utility using dual energy cardiac CT
ConclusionThe use of DECT adds new information of the plaque composition expressed by the effective-Z, which differs significantly in culprit lesions in comparison with non-culprit lesions. The use of the effective-Z improves the diagnostic sensitivity in detection of culprit lesions. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Echocardiographic screening for mitral valve prolapse in Turkish school children
AbstractWe determined the frequency of mitral valve prolapse (MVP) in healthy Turkish school children using the current echocardiographic diagnostic criteria. This epidemiological survey was performed on 2550 school children. All children were screened with echocardiography and the family of children with MVP were also screened. The prolapse of mitral leaflets into left atrium  ≥ 2 mm in parasternal long-axis view was used as diagnostic criteria. MVP was classified as classical or non-classical according to anterior mitral leaflet thickness. The thickness of anterior mitral leaflet, the extent of prol...
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Underfilling decreases left ventricular function in pulmonary arterial hypertension
AbstractTo evaluate the association between impaired left ventricular (LV) longitudinal function and LV underfilling in patients with pulmonary arterial hypertension (PAH). Thirty-nine patients with PAH and 18 age and sex-matched healthy controls were included. LV volume and left atrial volume (LAV) were delineated in short-axis cardiac magnetic resonance (CMR) cine images. LV longitudinal function was assessed from atrio-ventricular plane displacement (AVPD) and global longitudinal strain (GLS) was assessed using feature tracking in three long-axis views. LV filling was assessed by LAV and by pulmonary artery wedge pressu...
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Pacemaker lead-induced tricuspid regurgitation: consider leaflet remodeling
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Age- and gender-related reference values of cardiac morphology and function in cardiovascular magnetic resonance
AbstractCardiovascular magnetic resonance (CMR) is the reference standard for the quantitative assessment of cardiac morphology and function. The aim of the study was to determine age- and gender-related reference values for cardiac morphology and function according to current recommendations. 454 healthy volunteers (235 men, median age 52.0 (44.0 –59.0) years) underwent a standard CMR scan and were divided into six groups of nearly equal size with regard to sex (male, female) and age (21–47 years, 48–57 years, 58–84 years). Left ventricular end-diastolic (LV-EDV) and end-systolic (LV...
Source: The International Journal of Cardiovascular Imaging - January 22, 2021 Category: Radiology Source Type: research

Kidney function and the prognostic value of myocardial performance index
AbstractA decreased glomerular filtration rate (GFR) is a risk factor for cardiovascular disease even after adjustment for conventional risk factors. The myocardial performance index (MPI) is defined as (isovolumetric relaxation time (IVRT)  + isovolumetric contraction time (IVCT))/ejection time (ET). It has been shown to be an independent predictor of cardiovascular events. We hypothesized the MPI could prove valuable for assessing cardiac risk in subjects of the general population with decreased estimated GFR (eGFR). MPI was meas ured in 1915 subjects from a large general population prospective cohort study...
Source: The International Journal of Cardiovascular Imaging - January 21, 2021 Category: Radiology Source Type: research

Inflammation as a determinant of healing response after coronary stent implantation
AbstractCardiovascular disease remains the leading cause of death and morbidity worldwide. Inflammation plays an important role in the development of atherosclerosis and is associated with adverse clinical outcomes in patients after percutaneous coronary interventions. Data on stent elements that lead to excessive inflammatory response, proper identification of high –risk patients, prevention and treatment targeting residual inflammatory risk are limited. This review aims to present the role of inflammation in the context of evolving stent technologies and appraise the potential imaging modalities in detection of inf...
Source: The International Journal of Cardiovascular Imaging - January 21, 2021 Category: Radiology Source Type: research

Cardiac MRI assessment of the right ventricle pre-and post-kidney transplant
AbstractWorsening renal function in chronic kidney disease correlates with worsening right ventricular (RV) systolic function. We evaluated the association between kidney transplantation (KT) and RV structure and systolic function, and the relationships between RV and left ventricular (LV) changes, blood pressure, and specific cardiac biomarkers, in patients with end-stage kidney disease using cardiac magnetic resonance imaging (CMR).  In this prospective, multi-centre, cohort study, 39 adult patients on dialysis receiving KT and 42 patients eligible for, but not yet receiving KT, were recruited. CMR was performed at ...
Source: The International Journal of Cardiovascular Imaging - January 21, 2021 Category: Radiology Source Type: research

Application of survival classification and regression tree analysis for identification of subgroups of risk in patients with heart failure and reduced left ventricular ejection fraction
AbstractThe aim of this study was to identify by classification and regression tree (CART) analysis groups of patients with different survival patterns in a population of patients with heart failure and reduced left ventricular ejection fraction (HFrEF) by using standard methods of heart function assessment, as well as well as utilizing non-traditional approaches for determining hydration and nutritional status in HF patients —lung ultrasonography (LUS) and bioimpedance spectroscopy (BIS) analysis. Eligible patients with a left ventricular ejection fraction (LVEF) below 45% were identified via the daily echocardiogra...
Source: The International Journal of Cardiovascular Imaging - January 16, 2021 Category: Radiology Source Type: research

Inadequately low left ventricular mass in patients with significant aortic stenosis predicts favourable prognostic outcomes
AbstractIn patients with significant aortic stenosis (AS), the prognostic effect of the increase in left ventricular mass (LVM) in relation to one ’s hemodynamic load has been described. Inappropriately high LVM has been shown to predict adverse cardiovascular events. However, little is known about the prognostic impact of inadequately low LVM (i-lowLVM) in patients with significant AS. I-lowLVM was defined as the measured LVM 
Source: The International Journal of Cardiovascular Imaging - January 16, 2021 Category: Radiology Source Type: research