Statement from the North American Society for Cardiovascular Imaging on imaging strategies to reduce the scarcity of healthcare resources during the COVID-19 outbreak
AbstractCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an evolving global pandemic that is predicted to strain healthcare resources at multiple locations throughout North America and the World. As of April 6, 2020, the apex of infection rates is predicted to occur within 1 to 5  weeks at various locations. Widespread reports of personal protective equipment (PPE) shortages, and healthcare worker exposure to disease have become commonplace. To mitigate this crisis, we are suggesting imaging strategies that aim to use the least PPE, require the smallest nu...
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

Aortic valve microcalcification and cardiovascular risk: an exploratory study using sodium fluoride in high cardiovascular risk patients
Abstract18F-sodium fluoride (18F-NaF) has been used to access aortic stenosis in clinical research setting. It is known that its uptake is related with microcalcification. The purpose of this study was to assess the relationship between 18F-NaF uptake by the aortic valve and cardiovascular risk. Twenty-five patients with risk factors for cardiovascular disease, without known cardiovascular disease or aortic stenosis underwent PET-CT with 18F-NaF. Cardiovascular risk was assessed through the ASCVD (Atherosclerotic Cardiovascular Disease) risk calculator. Aortic valve 18F-NaF (AoVCUL) uptake was evaluated through the correct...
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

Impact of balloon mitral valvuloplasty on left ventricular rotational deformation: Magnetic Resonance Imaging follow up study
AbstractIn patients with rheumatic mitral stenosis (MS), some previous studies have investigated the influence of balloon mitral valvuloplasty (BMV) on left ventricular (LV) systolic function. However, the impact of BMV on LV twisting motion in this clinical setting has not been studied before yet. To describe changes in LV torsion in patients with rheumatic MS following BMV. Thirty patients (median age 33  years, 22 women) with isolated severe MS were studied. CMR myocardial tissue tagging was used for assessment of LV rotational deformation. LV torsion was calculated as the twist value (the net difference between ap...
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

The association of mechanical dyssynchrony and resynchronization therapy with survival in heart failure with a wide QRS complex: a two-world study
AbstractSetting up a randomized trial to assess the association of mechanical dyssynchrony (MD) and the success of cardiac resynchronization therapy (CRT) in heart failure with a wide QRS complex is ethically challenging. We therefore investigated this association in a retrospective cohort study observing different treatment strategies which were chosen based on the availability of health care resources. The survival of 500 patients from six Western European centers treated with CRT was compared to their 137 Eastern European counterparts not treated with CRT, with regard to the presence of MD. MD was visually assessed and ...
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

Assessment of left atrial mechanics and left ventricular functions using 3D speckle-tracking echocardiography in patients with inappropriate sinus tachycardia
AbstractPurposeInappropriate sinus tachycardia (IST) is defined as a sinus heart rate  >  100 bpm at rest (with a mean 24-h heart rate >  90 bpm not due to primary causes) and is associated with distressing symptoms of palpitations. The effect of IST on left atrial (LA) and left ventricular (LV) myocardial dynamics is uncertain. Thus, the aim of this study was to identify early changes in LA mechanics and LV myocardial functions in patients with IST using 3D-STE.MethodsSixty patients with IST and 65 age- and gender-matched controls were enrolled into the study. Conventional 2D echocardiogr...
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

Moving beyond two-dimensional screens to interactive three-dimensional visualization in congenital heart disease
AbstractBeginning with the discovery of X-rays to the development of three-dimensional (3D) imaging, improvements in acquisition, post-processing, and visualization have provided clinicians with detailed information for increasingly accurate medical diagnosis and clinical management. This paper highlights advances in imaging technologies for congenital heart disease (CHD), medical adoption, and future developments required to improve pre-procedural and intra-procedural guidance. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

Aortic valve calcification scoring with computed tomography: impact of iterative reconstruction techniques
AbstractTo investigate whether image reconstruction with iterative reconstruction (IR) affects aortic valve calcification (AVC) scoring and likelihood categorization of severe aortic stenosis (AS). In this IRB-approved retrospective study, we included 100 consecutive patients with AS (40 females; mean age 77  ± 10 years; age range: 36–99 years) undergoing CT prior to transcatheter aortic valve replacement. Non-enhanced, electrocardiography-gated CT of the heart was reconstructed with filtered back projection (FBP) and with advanced modeled IR at strength levels 1–5. AVC Agatston s...
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

Occupational eye dose to medical staff in various interventional cardiologic procedures: is the need for lead goggles the same in all groups of radiation workers?
In this study eye dose was measured for left and right eyes in three groups of radiation workers in angiography ward of Afshar hospital in various procedures using TLD. Measurements were done separately for cardiologists, nurses and radio-technologists in 100 procedures. The nurses functioned as surgical assistants and were usually close to the table. The correlation of staff dose to exposure parameters was also investigated. Eye dose in physicians were higher than other staff in all procedures. Also the left eye dose was considerably higher than right one, especially for physicians. The median equivalent dose per procedur...
Source: The International Journal of Cardiovascular Imaging - July 24, 2020 Category: Radiology Source Type: research

Multimodality imaging evaluation of saphenous vein graft peri-stent contrast staining enlargement
AbstractA patient with Takayasu arteritis who underwent CABG using a saphenous vein graft (SVG) experienced ventricular fibrillation due to total SVG occlusion. A drug-eluting stent was implanted; however, follow-up CAG demonstrated an advanced expansion of peri-stent contrast staining. Coronary computed tomography angiography revealed contrast media extending around the SVG. An intravascular ultrasound indicated a worsening stent malapposition and a significant positive remodeling. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 18, 2020 Category: Radiology Source Type: research

Associations of B-type natriuretic peptide (BNP) and dialysis vintage with CMRI-derived cardiac indices in stable hemodialysis patients with a preserved left ventricular ejection fraction
AbstractTo assess left ventricular myocardial native T1/T2 values and systolic strain and their associations with B-type natriuretic peptide (BNP) and dialysis vintage in hemodialysis (HD) patients with a preserved left ventricular ejection fraction (LVEF). Forty-three HD patients with end-stage renal disease (ESRD) but a preserved LVEF ( ≥ 50%) and 28 healthy volunteers were enrolled. BNP was measured at the time of cardiac magnetic resonance (CMR) measurements. Global native T1 and T2 values were significantly higher in the HD patients (native T1: 1056 ± 32 ms vs. 1006 ± 25 ms,p
Source: The International Journal of Cardiovascular Imaging - July 18, 2020 Category: Radiology Source Type: research

Silent cerebral infarction after percutaneous coronary intervention of chronic total occlusions (CTO) and non-CTOs
AbstractSilent cerebral infarctions (SCI) determined by neuron specific enolase (NSE) elevation may develop more during chronic total occlusion (CTO) percutaneous coronary interventions (PCI) than non-CTO interventions. Our aim was to examine CTO and non-CTO PCIs for SCI development. 100 consecutive CTO and 100 non-CTO PCI patients were enrolled. SCI was detected by serum NSE measurements performed at baseline and 12  h after the interventions. New NSE elevations >  12 ng/mL after the procedure were counted as SCI. Post-procedural NSE levels were found to be significantly higher in the CTO PCI gr...
Source: The International Journal of Cardiovascular Imaging - July 16, 2020 Category: Radiology Source Type: research

Fully automated quantification of left ventricular volumes and function in cardiac MRI: clinical evaluation of a deep learning-based algorithm
AbstractTo investigate the performance of a deep learning-based algorithm for fully automated quantification of left ventricular (LV) volumes and function in cardiac MRI. We retrospectively analysed MR examinations of 50 patients (74% men, median age 57  years). The most common indications were known or suspected ischemic heart disease, cardiomyopathies or myocarditis. Fully automated analysis of LV volumes and function was performed using a deep learning-based algorithm. The analysis was subsequently corrected by a senior cardiovascular radiologi st. Manual volumetric analysis was performed by two radiology trainees....
Source: The International Journal of Cardiovascular Imaging - July 15, 2020 Category: Radiology Source Type: research

Letter to the editor: is it time for imaging to level with pathology?
This article aims to call for a wider clinical application of CMR with more attention on its tissue characterization value. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 15, 2020 Category: Radiology Source Type: research

A new integrated approach to cardiac mechanics: reference values for normal left ventricle
AbstractThe association between left ventricular (LV) myocardial deformation and hemodynamic forces is still mostly unexplored. The normative values and the effects of demographic and technical factors on hemodynamic forces are not known. The authors studied the association between LV myocardial deformation and hemodynamic forces in a large cohort of healthy volunteers. One-hundred seventy-six consecutive subjects (age range, 16 –82; 51% women), with no cardiovascular risk factors or any relevant diseases, were enrolled. All subjects underwent an echo-Doppler examination. Both 2D global myocardial and endocardial lon...
Source: The International Journal of Cardiovascular Imaging - July 14, 2020 Category: Radiology Source Type: research

Diffusion-weighted imaging in hypertrophic cardiomyopathy: association with high T2-weighted signal intensity in addition to late gadolinium enhancement
AbstractDiffusion-weighted imaging (DWI) has been confirmed to be associated with late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM). In this context, we aimed to study whether DWI could reflect the active tissue injury and edema information of HCM which were usually indicated by T2 weighted images. Forty HCM patients were examined using a 3.0  T magnetic resonance scanner. Cine, T2-weighted short tau inversion recovery (T2-STIR), DWI and LGE sequences were acquired. T1 mapping was also included to quantify the focal and diffuse fibrosis. Cardiac troponin I (cTnI) was tested to assess the recently ...
Source: The International Journal of Cardiovascular Imaging - July 13, 2020 Category: Radiology Source Type: research

Diagnostic performance of fetal intelligent navigation echocardiography (FINE) in fetuses with double-outlet right ventricle (DORV)
AbstractThe main objective of this study was to investigate the diagnostic performance of FINE in generating and displaying 3 specific abnormal fetal echocardiography views such as left ventricular outflow tract (LVOT) view, right ventricular outflow tract (RVOT) view, and 3-vessels and trachea (3VT) view in fetuses with double-outlet right ventricle (DORV). In this prospective study, thirty fetuses diagnosed with DORV by fetal echocardiography in the second and third trimesters were enrolled. One or more STIC volume data-sets were collected from the 4-chamber view as initial view for each fetus, one optimal volume per fet...
Source: The International Journal of Cardiovascular Imaging - July 7, 2020 Category: Radiology Source Type: research

Abnormal ventricular contractile pattern associated with late systolic mitral prolapse: a two-dimensional speckle tracking study
AbstractWe sought to study the mechanics of ventricular contraction in patients with and outward basal  movement. Using echocardiographic parasternal long-axis views we retrospectively screened 760 echocardiograms to enroll 50 individuals with late systolic bileaflet prolapse, papillary muscle traction, and outward movement of the sub-annular base and posterior mitral annulus in late systole. Two-di mensional speckle tracking echocardiography was used to analyze the mechanics of contraction. Global and regional longitudinal strain values between the study group and 45 healthy control subjects were compared. The study ...
Source: The International Journal of Cardiovascular Imaging - July 6, 2020 Category: Radiology Source Type: research

Defining the left ventricular base in mitral valve prolapse: impact on systolic function and regurgitation
AbstractIn bileaflet mitral valve prolapse (BMVP) systolic leaflet displacement creates a pocket of blood on the left ventricular (LV) side of the leaflets, but on the atrial side of the annulus. This blood is excluded from the LV end-systolic volume if the mitral valve annulus is used to determine the most basal extent of the LV. The purpose of this study is to describe the quantitative implications of defining the LV base on mitral regurgitant severity and LV systolic function in BMVP. In 30 consecutive patients (53% male, 58  ± 14 years) with BMVP, LV endocardial and epicardial borders were det...
Source: The International Journal of Cardiovascular Imaging - July 5, 2020 Category: Radiology Source Type: research

Ischemia and outcome prediction by cardiac CT based machine learning
AbstractCardiac CT using non-enhanced coronary artery calcium scoring (CACS) and coronary CT angiography (cCTA) has been proven to provide excellent evaluation of coronary artery disease (CAD) combining anatomical and morphological assessment of CAD for cardiovascular risk stratification and therapeutic decision-making, in addition to providing prognostic value for the occurrence of adverse cardiac outcome. In recent years, artificial intelligence (AI) and, in particular, the application of machine learning (ML) algorithms, have been promoted in cardiovascular CT imaging for improved decision pathways, risk stratification,...
Source: The International Journal of Cardiovascular Imaging - July 3, 2020 Category: Radiology Source Type: research

Prognostic value of left ventricular longitudinal strain by speckle-tracking echocardiography in patients with sickle cell disease
This study was designed to examine the value of STE in predicting clinical outcome in adult patients with SCD. A total of 219 patients, mean age 33  ± 12 years were prospectively enrolled. Several clinical, laboratory and echocardiographic variables including left ventricular global longitudinal strain (LVGLS) by STE were assessed. The endpoint was a composite of the following events: (1) all-cause mortality, (2) three or more acute painf ul episodes that require hospitalization in one year, (3) acute chest syndrome and (4) hospitalization due to disease complication. The majority of the patients ...
Source: The International Journal of Cardiovascular Imaging - July 2, 2020 Category: Radiology Source Type: research

Potential impact of dynamic automated CT aortic annular measurements on outcomes for transcatheter aortic valve replacement sizing
AbstractTo determine the potential impact of automated computed tomography (CT) software used for aortic annular sizing for transcatheter aortic valve replacement (TAVR) on paravalvular leak (PVL) and major adverse cardiovascular events (MACE) as compared to standard CT manual measurement. In 60 TAVR patients (84  ± 7 years, 60% male), we evaluated the preprocedural CT scans. For the standard manual measurement, we measured the perimeter and area from a single cardiac phase deemed to be of maximum systolic opening. Valve type and size were determined by a multidisciplinary TAVR team per clinical r...
Source: The International Journal of Cardiovascular Imaging - July 2, 2020 Category: Radiology Source Type: research

From CT to artificial intelligence for complex assessment of plaque-associated risk
AbstractThe recent technological developments in the field of cardiac imaging have established coronary computed tomography angiography (CCTA) as a first-line diagnostic tool in patients with suspected coronary artery disease (CAD). CCTA offers robust information on the overall coronary circulation and luminal stenosis, also providing the ability to assess the composition, morphology, and vulnerability of atherosclerotic plaques. In addition, the perivascular adipose tissue (PVAT) has recently emerged as a marker of increased cardiovascular risk. The addition of PVAT quantification to standard CCTA imaging may provide the ...
Source: The International Journal of Cardiovascular Imaging - July 1, 2020 Category: Radiology Source Type: research

Reproducibility of cardiac magnetic resonance imaging in patients referred for the assessment of cardiac sarcoidosis; implications for clinical practice
AbstractCardiac sarcoidosis (CS) is an increasingly recognized condition, but cardiac magnetic resonance (CMR) image interpretation in these patients may be challenging as findings are often non-specific. The main objective of this study was to investigate the inter-reader agreement for the overall interpretation of CMR for the diagnosis of CS in an experienced reference center and investigate factors that may lead to discrepancies between readers. Consecutive patients undergoing CMR imaging to investigate for CS were included. CMR images were independently reviewed by two readers, blinded to all clinical, imaging and demo...
Source: The International Journal of Cardiovascular Imaging - June 30, 2020 Category: Radiology Source Type: research

Cardiac magnetic resonance imaging in Chagas ’ disease: a parallel with electrophysiologic studies
This article reviews the patterns of MF in CHD and correlate these patterns with electrogram patterns to predict risk of ventricular arrhythmias and sudden death. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - June 30, 2020 Category: Radiology Source Type: research

Comparison of global strain values of myocardium in beta-thalassemia major patients with iron load using specific feature tracking in cardiac magnetic resonance imaging
AbstractThalassemia defined a spectrum of diseases characterized by reduced or absent production of one of the globin chains of hemoglobin. High iron deposition in the myocardium may cause functional impairment even before any changes in left ventricular (LV) ejection fraction. These impairments may appear as changes in strain values. Early detection of myocardial dysfunction is essential for improving survival and preventing further complications. Therefore, this study aims to evaluate the cardiac strain patterns by Feature Tracking -Cardiac Magnetic Resonance Imaging (FT-CMR) method and their correlation with T2* values ...
Source: The International Journal of Cardiovascular Imaging - May 29, 2020 Category: Radiology Source Type: research

Estimation of total collagen volume: a T1 mapping versus histological comparison study in healthy Landrace pigs
AbstractRight ventricular biopsy represents the gold standard for the assessment of myocardial fibrosis and collagen content. This invasive technique, however, is accompanied by perioperative complications and poor reproducibility. Extracellular volume (ECV) measured through cardiovascular magnetic resonance (CMR) has emerged as a valid surrogate method to assess fibrosis non-invasively. Nonetheless, ECV provides an overestimation of collagen concentration since it also considers interstitial space. Our study aims to investigate the feasibility of estimating total collagen volume (TCV) through CMR by comparing it with the ...
Source: The International Journal of Cardiovascular Imaging - May 13, 2020 Category: Radiology Source Type: research

Early diastolic strain rate by two-dimensional speckle tracking echocardiography is a predictor of coronary artery disease and cardiovascular events in stable angina pectoris
This study aimed to clarify the diagnostic and prognostic potential of strain rate in patients with suspected stable angina pectoris (SAP). Strain rate by 2-dimensional speckle tracking echocardiography (2DSTE) has been suggested to be able to diagnose coronary artery disease (CAD) and predict cardiovascular events in various patient groups. Prospectively enrolled patients (n  = 296) with suspected SAP, no previous cardiac disease, and normal left ventricular ejection fraction were examined by 2DSTE, exercise ECG, and coronary angiography. Obstructive CAD was defined as stenosis ≥ 70% in&thin...
Source: The International Journal of Cardiovascular Imaging - May 13, 2020 Category: Radiology Source Type: research

Angiography-derived index of microcirculatory resistance as a novel, pressure-wire-free tool to assess coronary microcirculation in ST elevation myocardial infarction
AbstractImmediate assessment of coronary microcirculation during treatment of ST elevation myocardial infarction (STEMI) may facilitate patient stratification for targeted treatment algorithms. Use of pressure-wire to measure the index of microcirculatory resistance (IMR) is possible but has inevitable practical restrictions. We aimed to develop and validate angiography-derived index of microcirculatory resistance (IMRangio) as a novel and pressure-wire-free index to facilitate assessment of the coronary microcirculation. 45 STEMI patients treated with primary percutaneous coronary intervention (pPCI) were enrolled. Immedi...
Source: The International Journal of Cardiovascular Imaging - May 13, 2020 Category: Radiology Source Type: research

Sex differences in cardiac magnetic resonance features in patients with hypertrophic cardiomyopathy
AbstractWhether sex differences exist in cardiac magnetic resonance (CMR) findings in patients with hypertrophic cardiomyopathy (HCM) remain unknown. We sought to assess and compare CMR characteristics in male and female patients with HCM. From January-2006 to October-2017, 165 consecutive HCM patients evaluated with CMR were included. All clinical and complementary test information was prospectively collected. At the time of CMR evaluation women were older (70 [57 –75] vs. 61 [47–72] years, p = 0.02) and more symptomatic in terms of dyspnea (New York Heart Association class II–IV 47.2 vs. 2...
Source: The International Journal of Cardiovascular Imaging - May 12, 2020 Category: Radiology Source Type: research

Clinical application of four-dimensional noise reduction filtering with a similarity algorithm in dynamic myocardial computed tomography perfusion imaging
AbstractWe aimed to evaluate the effects of four-dimensional noise reduction filtering using a similarity algorithm (4D-SF) on the image quality and hemodynamic parameter of dynamic myocardial computed tomography perfusion (CTP). Sixty-eight patients who underwent dynamic myocardial CTP for the assessment of coronary artery disease were enrolled. Dynamic CTP was performed using a 320-row CT with low tube voltage scan (80  kVp). Two different datasets of dynamic CTP were reconstructed using iterative reconstruction (IR) alone and a combination of IR and 4D-SF. Qualitative (5-grade scale) and quantitative image quality ...
Source: The International Journal of Cardiovascular Imaging - May 11, 2020 Category: Radiology Source Type: research

CMR publications from China of the last more than 30 years
AbstractCardiovascular magnetic resonance (CMR) is a non-invasive imaging technology, gradually playing an irreplaceable role in the diagnosis and treatment of cardiovascular diseases. This review demonstrates the progress and research highlights of Chinese CMR publications of the last more than 30  years. At initial stage (1988 to 1997), CMR was introduced to evaluate cardiac anatomy, blood flow and ventricular function roughly in China. In the development stage (1998–2007), CMR began to play an important role in the diagnosis of cardiovascular and pericardial disease with the emergence of new techniques, such ...
Source: The International Journal of Cardiovascular Imaging - May 10, 2020 Category: Radiology Source Type: research

A heart with red flags
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - May 10, 2020 Category: Radiology Source Type: research

The evaluation of ventricular functions by speckle tracking echocardiography in preeclamptic patients
AbstractPreeclampsia is a maternal disorder of pregnancy characterized by concomitant increase in preload and afterload with end organ dysfunction. The aim of our study is to evaluate left ventricular (LV) and right ventricular (RV) functions with speckle tracking echocardiography in preeclamptic patients. Fifty-five preeclamptic (mean age: 30.7  ± 5.9 years) and 35 healthy pregnant women (mean age: 28.8 ± 5.7 years) of the same race, similar age and gestational week were consecutively included. The diagnosis of preeclampsia was based on the criteria proposed by the American Colleg...
Source: The International Journal of Cardiovascular Imaging - May 8, 2020 Category: Radiology Source Type: research

Giant sinus of Valsalva aneurysm mimicking severe pulmonary hypertension
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - May 8, 2020 Category: Radiology Source Type: research

Characterization of Fabry Disease cardiac involvement according to longitudinal strain, cardiometabolic exercise test, and T1 mapping
AbstractIn Anderson-Fabry disease (FD), we sought to evaluate relation between left ventricular (LV) hypertrophy, longitudinal strain (LS), myocardial T1 mapping and cardiopulmonary exercise parameters, and their prognostic value in term of cardiovascular outcomes. In this prospective, observational, monocentric study called “FABRY-Image”, we evaluated consecutive adult FD patients by echocardiography, cardiac magnetic resonance, and cardiopulmonary exercise testing. We investigated regional LS, the relations between LV hypertrophy, LS, T1 mapping, and VO2 peak and VE/VCO2, and the prediction of cardiovascular ...
Source: The International Journal of Cardiovascular Imaging - May 7, 2020 Category: Radiology Source Type: research

Very late-phase vascular response after everolimus-eluting stent implantation assessed by optical coherence tomography
We examined the vascular response in 39 patients with a total of 55 DESs [31 EESs (mean 54 months after stenting) and 24 first generation SES (mean 66 months after stenting)] by OCT. The frequency of lesions with any malapposed stent struts (19% vs. 46%, p = 0.035) and evagination (6% vs. 42%, p = 0.002) was significantly lower. Segments with malapposed stent struts were significantly shorter (0.4 ± 0.9 mm vs. 1.9 ± 3.5 mm, p = 0.024), maximal malapposition area and malapposition volume were significantly smaller (0.26&t...
Source: The International Journal of Cardiovascular Imaging - May 7, 2020 Category: Radiology Source Type: research

The Spectrum of Pregnancy-Associated Heart Failure Phenotypes: An Echocardiographic Study
AbstractCompare echocardiographic phenotypes of women presenting with peripartum heart failure. A retrospective case –control study of pregnant women (n = 86) presenting with PP-HF symptoms (i.e., dyspnea, PND, orthopnea) and objective examination and laboratory findings (lung congestion, elevated JVP and/or HJR, elevated brain natriuretic peptide [BNP] and pulmonary edema on chest X-ray). Three distinct phe notypes based on echocardiographically-defined LVEF were identified: (a) PP-HF with preserved ejection fraction (PP HFpEF, LVEF: >  50%); (b) PP-HF with midrange ejection fraction (...
Source: The International Journal of Cardiovascular Imaging - May 5, 2020 Category: Radiology Source Type: research

Cardiac cine CT approaching 1  mSv: implementation and assessment of a 58-ms temporal resolution protocol
AbstractClinical use of cardiac cine CT imaging is limited by high radiation dose and low temporal resolution. To evaluate a low radiation dose, high temporal resolution cardiac cine CT protocol in human cardiac CT and phantom scans. CT scans of a circulating iodine target were reconstructed using the conventional single heartbeat half-scan (HS, approx. 175  ms temporal resolution) and the 3-heartbeat multi-segment (MS, approx. 58 ms) algorithms. Motion artifacts were quantified by the root-mean-square error (RMSE). Low-dose cardiac cine CT scans were performed in 55 subjects at a tube potential of 80 kVp and cur...
Source: The International Journal of Cardiovascular Imaging - May 3, 2020 Category: Radiology Source Type: research

Angiography-based quantitative coronary contrast-flow ratio measurements correlate with myocardial ischemia assessed by stress MRI
AbstractContrast-flow quantitative flow ratio (cQFR) is a new technology for quantitative evaluation of coronary stenosis using computational fluid dynamics based on angiograms. The aim of this study was to assess the sensitivity and specificity of cQFR to detect myocardial ischemia using stress magnetic resonance imaging (MRI) as a reference standard. Patients who received stress MRI and coronary angiography were selected from the hospital database. Relevant ischemia on stress MRI was defined as a perfusion deficit in  ≥ 2 of 16 segments. cQFR was quantitated based on 3-dimensional quantitative coronary a...
Source: The International Journal of Cardiovascular Imaging - May 3, 2020 Category: Radiology Source Type: research

Speckle tracking evaluation in endurance athletes: the “optimal” myocardial work
AbstractTo analyze left ventricular myocardial deformation and contractile reserve in endurance athletes at rest and during exercise, and their possible correlations with functional capacity. The athlete ’s heart in endurance training is characterized by physiologic eccentric remodeling, with left ventricle adaptation at rest and echocardiographic parameters at low end of normality. Assessment of left ventricle systolic function and contractile reserve has an important role in the decision-making and in differential diagnosis with cardiomyopathies. Standard echo, lung ultrasound, left ventricle 2D speckle-tracking st...
Source: The International Journal of Cardiovascular Imaging - May 3, 2020 Category: Radiology Source Type: research

Decreased right ventricular longitudinal strain in children with hypoplastic left heart syndrome during staged repair and follow-up: does it have implications in clinically stable patients?
AbstractThe principal aim of this study was to evaluate changes in systolic function in the single right ventricle (SRV), during progression of the same patient through the three stages of surgical repair for hypoplastic left heart syndrome and during a 5-year follow-up. We hypothesize that, SRV global longitudinal strain (GLS) will be low during 3 stages of repair even in stable patients. We retrospectively evaluated 140 echocardiograms in 20 patients with HLHS (ages 0 –11.3 years), before and after 3 stages of surgical palliation. Five-year follow-up data were available in all 20 patients. Controls with struct...
Source: The International Journal of Cardiovascular Imaging - May 2, 2020 Category: Radiology Source Type: research

Correlation of left atrial strain with left ventricular end-diastolic pressure in patients with normal left ventricular ejection fraction
AbstractLeft ventricular diastolic dysfunction (LVDD) remains challenging to be assessed by echocardiography. We sought to explore the relationship between left atrial strain and left ventricular (LV) diastolic function in patients with normal left ventricular ejection fraction (LVEF) by invasive left-heart catheterization. 55 consecutive individuals with LVEF  >  50% underwent LV catheterization. Standard transthoracic echocardiography was performed during 12 h before or after the procedure. Left atrial (LA) strain were obtained by speckle tracking echocardiography. When LVEF ≥ 50%, ...
Source: The International Journal of Cardiovascular Imaging - May 2, 2020 Category: Radiology Source Type: research

Comparative effectiveness of coronary artery stenosis and atherosclerotic plaque burden assessment for predicting 30-day revascularization and 2-year major adverse cardiac events
AbstractPurposeTo provide comparative prognostic information of coronary atherosclerotic plaque volume and stenosis assessment in patients with suspected coronary artery disease (CAD).MethodsWe followed 372 patients with suspected or known CAD enrolled in the CORE320 study for 2 years after baseline 320-detector row cardiac CT scanning and invasive quantitative coronary angiography (QCA). CT images were analyzed for coronary calcium scanning (CACS), semi-automatically derived total percent atheroma volume (PAV), segment stenosis score (SSS), in addition to traditional stenosis assessment ( ≥ 50%) by CT and QCA fo...
Source: The International Journal of Cardiovascular Imaging - May 1, 2020 Category: Radiology Source Type: research

Periaortic adipose tissue volume is associated with sclerotic changes in the adjacent aortic valve
In this study, we investigated the relationship between periaortic adipose tissue volume and sclerotic changes in the adjacent aortic valve. In this retrospective study, 80 patients with a concurrent MSCT and echocardiography in the last 6 months were enrolled. Echocardiographic examinations were retrospectively evaluated regarding the presence of aortic sclerosis. Periaortic adipose tissue volume was calculated on a computer assisted work station (Leonardo Workstation, Siemens, Erlangen, Germany) by an experienced radiologist. Patient group (61.63  ± 8.55 years and 50% male) and the control group (61....
Source: The International Journal of Cardiovascular Imaging - April 19, 2020 Category: Radiology Source Type: research

Reliability of non-contrast magnetic resonance angiography-derived aortic diameters in Marfan patients: comparison of inner vs. outer vessel wall measurements
AbstractAortic diameter measurements play a crucial role for the indication of aortic root surgery in Marfan patients. However, for magnetic resonance angiography (MRA)-derived measurements, there is no consensus on whether the aortic wall should be included or excluded in the aortic diameter. The purpose of this retrospective study was to compare the reliability of non-contrast bright blood MRA aortic inner-to-inner and outer-to-outer edge measurements in patients with Marfan syndrome. Forty Marfan patients underwent ECG-gated balanced steady-state free-precession MRA of the aorta at 1.5  T. Two readers independently...
Source: The International Journal of Cardiovascular Imaging - April 19, 2020 Category: Radiology Source Type: research

Cardiac MR manifestations in two cases of PRKAG2 mutations in a Chinese family
AbstractPRKAG2 syndrome (PS) is a rare autosomal dominant syndrome that mainly presents with hypertrophic cardiomyopathy, ventricular preexcitation, and conduction abnormalities. Few reports have demonstrated the morphologic manifestation of patients with PRKAG2 gene defect. This case report demonstrates the cardiac magnetic resonance characteristics of the PS patients from a Chinese family. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - April 19, 2020 Category: Radiology Source Type: research

Comprehensive plaque assessment with serial coronary CT angiography: translation to bedside
AbstractThe purpose of this review is to highlight the utility of comprehensive plaque assessment by serial coronary computed tomography angiography (CCTA) to understand atherosclerosis and its effect on cardiovascular risk stratification and management. CCTA is a validated, noninvasive imaging modality for coronary atherosclerotic plaque characterization. Numerous clinical trials have used approach of serial CCTA to demonstrate the potential benefits of multiple treatment strategies to reduce coronary plaque progression and its translation to benefits with cardiovascular outcomes. Serial CCTA trials for cardiovascular the...
Source: The International Journal of Cardiovascular Imaging - April 18, 2020 Category: Radiology Source Type: research

Left ventricular radial strain impairment precedes hypertrophy in Anderson –Fabry disease
Abstract In Anderson –Fabry disease (AFD), left ventricular (LV) radial function has been scarcely investigated. We hypothesized that LV function may be affected by disease specific mechanisms and sought to comprehensively evaluate LV radial, circumferential and longitudinal function in a large population of AFD patie nts looking at the influence of LV geometry and fibrosis. We prospectively studied 94 consecutive AFD patients (41.5 ± 14.5 years; 41 men) with preserved LV ejection fraction (EF) utilizing speckle-tracking echocardiography. A subset of patients underwent gadolinium-enhanced car...
Source: The International Journal of Cardiovascular Imaging - April 17, 2020 Category: Radiology Source Type: research

Grading of aortic regurgitation by cardiovascular magnetic resonance and pulsed Doppler of the left subclavian artery: harmonizing grading scales between imaging modalities
AbstractTransthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR) are current standard for assessing aortic regurgitation (AR). Regurgitant fraction (RF) can also be estimated by Doppler examination of the left subclavian artery (LSA-Doppler). However, a comparison of AR grading scales using these methods and a TTE multiparametric approach as reference is lacking. We evaluated the severity of AR in 73 patients (58  ± 15 years; 57 men), with a wide spectrum of AR of the native valve. Using a recommended TTE multiparametric approach the AR was divided in none/trace (n =&thinsp...
Source: The International Journal of Cardiovascular Imaging - April 17, 2020 Category: Radiology Source Type: research

MDCT planning of trans catheter aortic valve implantation (TAVI): determination of optimal c-arm angulation
AbstractA fluoroscopic view perpendicular to the aortic valve annulus is required during transcatheter aortic valve implantation (TAVI) for obtaining an optimal deployment of the bioprosthesis. By predicting c-arm angulation, pre-procedural MDCT could decrease the number of aortograms, shorten the time of the procedure and reduce the amount of intra-arterial contrast agent. The aim of our study was to assess the accuracy of MDCT in predicting c-arm angulation at the cath. lab. In this single center study, we investigated MDCT prediction of c-arm angulation in patients having undergone a TAVI procedure using SAPIEN 3 ® ...
Source: The International Journal of Cardiovascular Imaging - April 17, 2020 Category: Radiology Source Type: research