Left atrial mechanics in children: insights from new applications of strain imaging
AbstractOur principal aim was to describe functional changes in dilated left atrium (LA) of children by using new applications of LA strain. We studied 66 patients (age range 0.2 –22 years) consisting of 33 with LA enlargement. We utilized speckle-tracking imaging for assessment LA longitudinal strain (S) and longitudinal displacement (D). S–D loops were generated by plotting S and D data along Y and X axes, respectively. We also measured noninvasive LA stiffness index,\(=\frac{{E/e^{\prime}}}{{LA~peak~strain}}~\) (%−1). Peak S in controls was 51.16  ± 19.45% versus 23.16 ...
Source: The International Journal of Cardiovascular Imaging - August 16, 2018 Category: Radiology Source Type: research

Right ventricular septomarginal trabeculation hypertrophy is associated with disease severity in patients with pulmonary arterial hypertension
AbstractTo characterize the morphological change in the right ventricle (RV) of patients with pulmonary artery hypertension (PAH) and further explore the correlation between septomarginal trabeculation (SMT) and right ventricular (RV) function, myocardial fibrosis, and exercise capacity in patients with PAH. Sixty untreated PAH patients were prospectively included from May 2016 to April 2017. All patients underwent comprehensive clinical evaluation and cardiac magnetic resonance (CMR). The area and diameter of the basal segment of SMT, and the mass of SMT were measured on cine SSFP images. Relationship between parameters o...
Source: The International Journal of Cardiovascular Imaging - August 14, 2018 Category: Radiology Source Type: research

Computed tomography showing formation of caseous calcification of the mitral annulus over time
AbstractCaseous calcification of the mitral annulus (CCMA) is a rare variant of mitral annulus calcification. Herein, we present computed tomographic images of formation of CCMA over time. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - August 14, 2018 Category: Radiology Source Type: research

The association of right ventricular dysfunction with in-hospital and 1-year outcomes in anterior myocardial infarction
In this study, we evaluated the prognostic effect of RV dysfunction on in-hospital and long-term outcomes in patients with first anterior STEMI. A total of 350 patients without known coronary artery disease with first anterior STEMI and treated with primary percutaneous coronary intervention were prospectively enrolled in this study. In-hospital and long-term outcomes were compared between two groups of with or without RV dysfunction. In-hospital mortality was significantly higher in the RV dysfunction group (26.7% vs. 1.6%, P  
Source: The International Journal of Cardiovascular Imaging - August 14, 2018 Category: Radiology Source Type: research

Basal leaflet thickening and color paucity in the echocardiographic evaluation of subclinical leaflet thrombosis after transcatheter aortic valve replacement
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - August 14, 2018 Category: Radiology Source Type: research

Initial application of three-dimensional speckle-tracking echocardiography to detect subclinical left ventricular dysfunction and stratify cardiomyopathy associated with Duchenne muscular dystrophy in children
AbstractThree-dimensional (3D) speckle-tracking echocardiography (STE) is a new imaging modality used for quantitative analysis of left ventricular (LV) function. The aim of this study is to assess the value of 3D STE in early detection of subclinical myocardial involvement in children with Duchenne muscular dystrophy (DMD). Fifty-six children with DMD (mean age, 8.8  ± 1.9 years) and 31 age-matched control subjects were studied. Patients were subdivided into two groups by age: ≤ 8 or>  8 years. Standard echocardiography examinations were performed to measure LV size and e...
Source: The International Journal of Cardiovascular Imaging - August 13, 2018 Category: Radiology Source Type: research

Association with right atrial strain with right atrial pressure: an invasive validation study
AbstractEchocardiographic assessment of right atrial pressure (RAP) from inferior vena cava (RAPIVC) dimension may underestimate catheter-derived (RAPC). As right atrial (RA) deformation, measured by speckle tracking, is preload-dependent, we hypothesized that RA strain may improve estimation of RAPC. Right atrial strain components [RA reservoir function ( ƐR), peak RA contraction (ƐCT) and RA conduit function (ƐCD)] were measured in 125 of 175 patients who had echocardiography and invasive measures of RAP (median difference 1 day). To determine whether RA strain measures differentiated patients with correct vs inc...
Source: The International Journal of Cardiovascular Imaging - August 9, 2018 Category: Radiology Source Type: research

Presence of aortic root vortex formation after TAVI with CENTERA confirmed using 4D-flow magnetic resonance imaging
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - August 9, 2018 Category: Radiology Source Type: research

Risk of cardiac tachyarrhythmia in patients with repaired tetralogy of Fallot: a multicenter cardiac MRI based study
AbstractCardiac tachyarrhythmias are the leading cause of morbidity and mortality in patients with repaired tetralogy of Fallot (TOF). We evaluated risk factors for sustained ventricular tachyarrhythmia (VT) and atrial tachyarrhythmia (ATA) in these patients. Patients (n  = 319) who underwent cardiac magnetic resonance (CMR) imaging at two tertiary centers between 2007 and 2016 were assessed. Potential risk markers, based on history, cardiac magnetic resonance imaging (CMR), electrocardiography (ECG) and echocardiography, were analyzed for prediction of the prim ary endpoint of VT, and the secondary endpoint ...
Source: The International Journal of Cardiovascular Imaging - August 9, 2018 Category: Radiology Source Type: research

Radiation exposure and coronary artery calcium scans in the society for heart attack prevention and eradication cohort
In this study, we report the radiation exposure of CAC scoring from the Society for Heart Attack Prevention and Eradication (SHAPE) early detection program cohort sites, which spanned multiple centers using 64-MDCT (multi-detector computed tomography) sc anners. We reviewed radiation exposure in milliSieverts (mSv) for 82,214 participants from the SHAPE early detection program cohort who underwent CAC scoring. This occurred over a 2.5-year period (2012–2014) divided among 33 sites in 7 countries with four different types 64-MDCT scanners. The effe ctive radiation dose was reported as mSv. Mean radiation dosing amongs...
Source: The International Journal of Cardiovascular Imaging - August 6, 2018 Category: Radiology Source Type: research

Intra-thoracic adiposity is associated with impaired contractile function in patients with coronary artery disease: a cardiovascular magnetic resonance imaging study
AbstractThe influence of visceral adiposity on left ventricular remodeling following coronary artery disease (CAD)-related events has not been examined to date. Using magnetic resonance imaging (MRI) we explored intra-thoracic fat volume (ITFV) and strain-based markers of adverse remodeling in patients with CAD. Forty-seven patients with known CAD (25 with prior MI, 22 without prior MI) were studied. ITFV was quantified using previously validated imaging techniques. Myocardial strain was derived from cine MRI using a validated 3D feature-tracking (FT) software. Segmental LGE quantification was performed and was used to inc...
Source: The International Journal of Cardiovascular Imaging - August 4, 2018 Category: Radiology Source Type: research

Reference values of left atrial size and function according to age: should we redefine the normal upper limits?
AbstractDifferent cut-offs have been proposed for left atrial (LA) size. Furthermore, conflicting results have been reported about the influence of age on LA size and data on the impact of age on LA myocardial function are scanty. The aim of this study was to derive references values for LA size and function in healthy subjects and to evaluate the impact of age. We conducted a systematic literature search of MEDLINE database. We included only studies evaluating healthy subjects, with age ranged between 18 and 80  years. Parameters were compared among four age groups,  45–60,>  60 years. Thr...
Source: The International Journal of Cardiovascular Imaging - August 3, 2018 Category: Radiology Source Type: research

Geometrical and functional cardiac changes after cardiac surgery: a phisiopatological explanation based on speckle tracking
AbstractCardiac surgery induces geometrical and functional changes, which are not clearly explained. Objective: to investigate the physiopathology of the heart after cardiac surgery using advanced techniques of echocardiography. Thirty patients undergoing cardiac surgery had echocardiographic study prior and after surgery. Left and right ventricular (RV) longitudinal displacement and strain were studied with speckle-tracking. Using longitudinal displacement, we defined a static longitudinal reference-point (sLRP) to which the other segments moved during systole. Transversal displacement and global function were determined ...
Source: The International Journal of Cardiovascular Imaging - August 2, 2018 Category: Radiology Source Type: research

15-O-water myocardial flow reserve PET and CT angiography by full hybrid PET/CT as a potential alternative to invasive angiography
AbstractCombined myocardial flow reserve (MFR) by PET and CT coronary angiography (CTA) is a promising tool for assessment of coronary artery disease. Prior analyses of MFR/CTA has been performed as side-by-side interpretation, not as volume rendered, full hybrid analysis, withfused MFR/CTA. We aimed to: (i) establish a method for full hybrid analysis of MFR/CTA, (ii) validate the inter- and intra-observer reproducibility of MFR values, and (iii) determine the diagnostic value of side-by-side versus full hybrid MFR/CTA with 15-O-water PET. Forty-four outpatients scheduled for invasive coronary angiography (ICA) were enroll...
Source: The International Journal of Cardiovascular Imaging - July 31, 2018 Category: Radiology Source Type: research

The value of speckle-tracking echocardiography in identifying right heart dysfunction in patients with chronic thromboembolic pulmonary hypertension
AbstractRight ventricular (RV) function is a significantly important factor in the determination of the prognosis of chronic thromboembolic pulmonary hypertension (CTEPH) patients. Speckle-tracking echocardiography (STE) is an angle-independent new technique for quantifying myocardial deformation that is capable of providing data on multiple parameters including longitudinal and transverse information of the myocardium. In the present study, we aimed to study the advantages of STE-derived parameters in identifying RV dysfunction in CTEPH patients. Sixty CTEPH patients (mean age: 55  years ± 13 yea...
Source: The International Journal of Cardiovascular Imaging - July 30, 2018 Category: Radiology Source Type: research

Diagnostic performance of machine-learning-based computed fractional flow reserve (FFR) derived from coronary computed tomography angiography for the assessment of myocardial ischemia verified by invasive FFR
AbstractTo explore the diagnostic performance of a machine-learning-based (ML-based) computed fractional flow reserve (cFFR) derived from coronary computed tomography angiography (CCTA) in identifying ischemia-causing lesions verified by invasive FFR in catheter coronary angiography (ICA). We retrospectively studied 117 intermediate coronary artery lesions [40 –80% diameter stenosis (DS)] from 105 patients (mean age 62 years, 32 female) who had undergone invasive FFR. CCTA images were used to compute cFFR values on the workstation. DS and the myocardium jeopardy index (MJI) of coronary stenosis were also assessed wit...
Source: The International Journal of Cardiovascular Imaging - July 30, 2018 Category: Radiology Source Type: research

Long term evaluation of electromechanical delay in patients with atrial septal defect after transcatheter closure
AbstractSome studies have been showed that electromechanical delay, which may pose an increased tendency to atrial fibrillation, may prolong in patients with various clinical conditions. In addition, the electromechanical delay in patients with secundum type atrial septal defect (ASD) compared to healthy people have been reported previously. Therefore, in the present study, we prospectively evaluated the mid-term and long-term effects of the transcatheter closure of secundum type ASD on the lateral atrial conduction time (PA), septal PA, tricuspid PA, left and right intra-atrial electromechanical delay (ILeft-EMD and IRigh...
Source: The International Journal of Cardiovascular Imaging - July 30, 2018 Category: Radiology Source Type: research

Peak left atrial strain as a single measure for the non-invasive assessment of left ventricular filling pressures
AbstractEchocardiographic assessment of left ventricular (LV) filling pressures is performed using a multi-parametric algorithm. Left atrial (LA) strain was recently found to accurately classify the degree of diastolic dysfunction. We hypothesized that LA strain could be used as a stand-alone marker and sought to identify and test a cutoff, which would accurately detect elevated LV pressures. We studied 76 patients with a spectrum of LV function who underwent same-day echocardiogram and invasive left-heart catheterization. Speckle tracking was used to measure peak LA strain. The protocol involved a retrospective derivation...
Source: The International Journal of Cardiovascular Imaging - July 30, 2018 Category: Radiology Source Type: research

CMR-derived extracellular volume fraction (ECV) in asymptomatic heart transplant recipients: correlations with clinical features and myocardial edema
AbstractMyocardial interstitial expansion seems to be fundamental to the process of adverse left ventricular remodeling. Recent evidence has shown that the extracellular volume fraction (ECV) derived from cardiovascular magnetic resonance (CMR) can be used as a noninvasive method to quantify myocardial interstitial volume in a range of heart diseases. Our aim was to determine whether ECV is increased in asymptomatic orthotopic heart transplant (HTx) patients and its associations with clinical features and T2 values, the elevation of which usually suggests myocardial edema. A group of asymptomatic cardiac transplant recipie...
Source: The International Journal of Cardiovascular Imaging - July 28, 2018 Category: Radiology Source Type: research

Coronary artery anomalies on preoperative cardiac CT in children with tetralogy of Fallot or Fallot type of double outlet right ventricle: comparison with surgical findings
This study was conducted to evaluate incidence and diagnostic accuracy of preoperative cardiac CT for identifying detailed coronary artery anatomy in these patients. Coronary artery anatomy on preoperative cardiac CT exams in 318 children with tetralogy of Fallot or Fallot type of double outlet right ventricle were reviewed and compared with surgical findings. Incidences of total and surgically critical coronary artery anomalies, concordance rate between cardiac CT and surgical findings, and diagnostic accuracy of cardiac CT were assessed. In addition, the types of surgical modifications for surgically critical coronary ar...
Source: The International Journal of Cardiovascular Imaging - July 26, 2018 Category: Radiology Source Type: research

Correction to: Imaging the myocardial ischemic cascade
In the original publication of the article, the seventh author name “Matthias Gutberlet” has been misspelt (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 24, 2018 Category: Radiology Source Type: research

Value of low-dose dobutamine stress echocardiography on defining true severe low gradient aortic stenosis in patients with preserved left ventricular ejection fraction
AbstractLow-dose dobutamine stress echocardiography (DSE) is a valuable tool to distinguish true-severe (TS) from pseudo-severe (PS) low gradient aortic valve stenosis (LGAS) in patients with reduced left ventricular ejection fraction (LVEF). However, only scanty studies reported the clinical utility of DSE in differentiating TS-LGAS patients with preserved LVEF. We investigated the clinical utility of DSE in LGAS patients with preserved LVEF and the echocardiographic determinants suggestive of TS-LGAS. 130 consecutive LGAS patients [indexed aortic valve area (AVA)  ≤ 0.6cm2/m2 and mean trans-aortic pressu...
Source: The International Journal of Cardiovascular Imaging - July 23, 2018 Category: Radiology Source Type: research

Coronary sinus flow is reduced in methamphetamine abusers: a transthoracic echocardiographic study
AbstractTo compare the coronary sinus flow among healthy participants, methamphetamine abusers without chest pain and those with chest pain. One hundred and eight methamphetamine abusers: 53 ones without chest pain, 55 ones with chest pain, free of ascertained coronary artery disease, were enrolled in this study. A control group of 50 age-matched male healthy participants was studied for comparison. Standard 2D, flow and tissue Doppler echo with measurements of cardiac morphologic and functional indicators, coronary sinus flow, and inferior vena cava (IVC) ultrasound with measurements of the IVC dimensions and their collap...
Source: The International Journal of Cardiovascular Imaging - July 21, 2018 Category: Radiology Source Type: research

The effect of heart rate on coronary plaque measurements in 320-row coronary CT angiography
AbstractRepeatability of quantitative assessment of atherosclerotic plaques is important for the accurate detection of high-risk plaques in coronary CT angiography (CTA). We assessed the effect of heart rate (HR) on plaque CT number using a coronary artery model and a cardiac phantom capable of simulating cardiac motion. The coronary artery model with luminal stenosis on a cardiac phantom was imaged with a simulated HR of 0, 50, 60, and 70 beats per minute using a 320-row CT scanner. We reconstructed CT images for cardiac diastolic phases (for 75% R –R interval) using filtered back projection (FBP), hybrid iterative ...
Source: The International Journal of Cardiovascular Imaging - July 20, 2018 Category: Radiology Source Type: research

Imaging the myocardial ischemic cascade
AbstractNon-invasive imaging plays a growing role in the diagnosis and management of ischemic heart disease from its earliest manifestations of endothelial dysfunction to myocardial infarction along the myocardial ischemic cascade. Experts representing the North American Society for Cardiovascular Imaging and the European Society of Cardiac Radiology have worked together to organize the role of non-invasive imaging along the framework of the ischemic cascade. The current status of non-invasive imaging for ischemic heart disease is reviewed along with the role of imaging for guiding surgical planning. The issue of cost effe...
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Cardiac computed tomography compared with two-dimensional transesophageal echocardiography for the detection and assessment of atrial septal pouches
AbstractThe aim of this study is to compare the two-dimensional transesophageal echocardiography (2D-TEE) with multi-slice computed tomography (MSCT) and with autopsied material to evaluate the ability and precision of the imaging methods for the detection and assessment of septal pouch (SP). One hundred and fifty patients that underwent both 2D-TEE and MSCT and 50 autopsied human hearts were investigated. In MSCT, the interatrial septum was classified as a left SP in 37.3%, right SP in 3.3%, and patent foramen ovale (PFO) channel in 3.3%. In 2D-TEE, the interatrial septum was classified as a left SP in 39.3%, right SP in ...
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Influence of tube potential on quantitative coronary plaque analyses by low radiation dose computed tomography: a phantom study
AbstractPrevious studies have shown that employing the low dose computed tomography (CT) technique based on low tube potential reduces the radiation dose required for the coronary artery examination protocol. However, low tube potential may adversely influence the CT number of plaque composition. Therefore, we aimed to determine whether quantitative atherosclerotic plaque analysis by a multi-slice, low radiation dose CT protocol using 80 kilovolts (kV) yields results comparable to those of the standard 120  kV protocol. Artificial plaque samples (n = 17) composed of three kinds of plaque were scanned at ...
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Implication of coronary CT angiography combined with four-dimensional speckle tracking echocardiography for predicting major adverse cardiac events
AbstractCoronary computed tomography angiography (CCTA) can provide abundant information about the anatomy of the coronary artery. However, this modality is limited in evaluation of myocardial function. Four-dimensional speckle tracking echocardiography (4DSTE) is a novel and sensitive technique for quantitative evaluation of myocardial deformation. We estimated the value of these imaging modalities to predict the risk of MACE in 209 patients with suspected coronary artery disease(CAD) after a median follow-up of 727 days. Three models were established: (1) CCTA alone, (2) CCTA combined with 4DSTE, and (3) CCTA combined wi...
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Diffuse fibrosis is common in the left, but not in the right ventricle in patients with transposition of the great arteries late after atrial switch operation
AbstractIn adult patients with transposition of the great arteries (TGA) late after atrial switch operation (AtSO), each of the ventricles is faced with a profoundly different pressure regimen from the one they are meant to support in normal conditions. The extent of diffuse fibrosis of the right ventricle (RV) and left ventricle (LV) in these patients remains incompletely investigated. Aim of this study was to quantify the degree of fibrosis of the unloaded LV and of the overloaded RV by determining the myocardial extracellular volume (ECV) with non-invasive techniques as T1 mapping. We determined ECV by cardiac magnetic ...
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Functional classification of aortic regurgitation using cardiac computed tomography: comparison with surgical inspection
AbstractIn patients with aortic regurgitation (AR), a precise preoperative assessment of aortic valve (AV) pathology is important if AV repair or sparing operation is an alternative option. The aim of this study was to assess the diagnostic accuracy of computed tomography (CT) for evaluating the AR mechanism compared with surgical inspection. 59 patients with AR who underwent AV surgery and preoperative cardiac CT were evaluated. AR mechanism was classified into type 1 (aortic dilatation or cusp perforation), type 2 (prolapsed cusp) and type 3 (cusp retraction). Agreement between CT and surgical inspection was obtained. Co...
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Noise reduction technology reduces radiation dose in chronic total occlusions percutaneous coronary intervention: a propensity score-matched analysis
In conclusion, compared with a Standard system, the use of NRT i n CTO PCI is associated with lower patient radiation dose and similar image quality. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Three-dimensional full automated software in the evaluation of the left ventricle function: from theory to clinical practice
AbstractLeft ventricular systolic function evaluation is an essential part of all transthoracic echocardiographic (TTE) studies. 3D echocardiography (3DE) is superior to 2D and is recommended as the method of choice. However, since it is time consuming and requires training, it is rarely performed. Different automatic analysis software tries to overcome these limitations but they need to be accurate and reproducible before they can be used clinically. The aim of this study was to test the accuracy and reproducibility of new 3D automatic quantitative software in everyday clinical practice. 69 patients referred to our Echo L...
Source: The International Journal of Cardiovascular Imaging - July 19, 2018 Category: Radiology Source Type: research

Correction to: Left atrial myocardial dysfunction after chronic abuse of anabolic androgenic steroids: a speckle tracking echocardiography analysis
In the original publication of the article, the seventh author name “Giampaolo Tocci” has been misspelt. The correct name is given in this. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 17, 2018 Category: Radiology Source Type: research

Relationship between cardiovascular risk factors and myocardial strain values of both ventricles in asymptomatic Asian subjects: measurement using cardiovascular magnetic resonance tissue tracking
AbstractThe purpose of this study was to evaluate the association between myocardial deformation parameters and cardiovascular risk factors in asymptomatic Asian subjects and to provide reproducibility for deformation parameters of both ventricles using cardiovascular magnetic resonance (CMR) tissue tracking (TT). We enrolled 129 asymptomatic healthy adults who underwent CMR and assessed the cardiovascular risk factors in all individuals. All subjects had normal left ventricular systolic function. Commercial software was used to derive myocardial deformation parameters of both ventricles from short-axis cine images and lon...
Source: The International Journal of Cardiovascular Imaging - July 17, 2018 Category: Radiology Source Type: research

3D myocardial deformation analysis from cine MRI as a marker of amyloid protein burden in cardiac amyloidosis: validation versus T1 mapping
This study identifies strong associations b etween 3D myocardial strain and T1-mapping based markers of regional amyloid protein deposition. These findings support expanded investigation of myocardial strain as a surrogate marker of response to novel therapeutic strategies in patients with cardiac amyloidosis. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 16, 2018 Category: Radiology Source Type: research

Assessment of left atrial function using speckle tracking echocardiography in ankylosing spondylitis: a case-control study
AbstractThe aim of this study is to assess the left atrium (LA) deformation parameters by using 2D speckle tracking echocardiography (2D-STE) in ankylosing spondylitis (AS) patients and to evaluate the relationship between these parameters and AS clinical indexes. 30 patients with AS (22 males, 8 females) and 30 healthy individuals (19 males, 11 females) were enrolled in this study. Transthoracic echocardiography was performed to both groups. Besides the conventional echocardiographic parameters, the LA strain parameters; including systolic-reservoir (LA S-S), early diastolic-conduit (LA S-E), late diastolic-contraction (L...
Source: The International Journal of Cardiovascular Imaging - July 16, 2018 Category: Radiology Source Type: research

Myocardial deformation and volume of exercise: a new overlap between pathology and athlete ’s heart?
AbstractRegular physical exercise induces cardiac adaptations that can overlap pathological conditions. Controversy still persists about the variability of myocardial deformation in different types and intensity of exercise. The aim of this study was to assess myocardial longitudinal deformation in athletes with different level of exercise. Two groups of young athletes involved in endurance sports characterized by high intensity dynamic component were enrolled. According to the level and the number of exercise training hours/week, two groups were defined:Group 1—high level (national/international and ≥ 20 t...
Source: The International Journal of Cardiovascular Imaging - July 14, 2018 Category: Radiology Source Type: research

Intravascular ultrasound-guided drug-eluting stent implantation is associated with improved clinical outcomes in patients with unstable angina and complex coronary artery true bifurcation lesions
AbstractStenting coronary artery bifurcation lesion is associated with suboptimal clinical results. Clinical improvement by intravascular ultrasound (IVUS) guided bifurcation stenting is controversial because small-side-branch (SB), low-risk patients and false bifurcations were included in previous studies that had no exact IVUS criteria for optimal stent expansion. We sought determine whether IVUS guidance is superior to angiography guidance for patients with true and complex bifurcation lesions. Between July 2006 and July 2012, 1465 patients with unstable angina and Medina 1,1,1 or 0,1,1 coronary bifurcation lesions were...
Source: The International Journal of Cardiovascular Imaging - July 6, 2018 Category: Radiology Source Type: research

Cardiac myxoma: a contemporary multimodality imaging review
AbstractCardiac myxoma (CM) is by far the most common primary benign cardiac tumor, typically arising in the left atrium with an attachment point in the fossa ovalis region. Although the etiology of CM remains unclear, we know that this endocardial-based mass originates from undifferentiated mesenchymal cells. Continuous technical improvements in the field of echocardiography since the 1960s has profoundly changed the diagnostic approach by allowing a good tumor detection as well as the preoperative planning by providing crucial information concerning the attachment point location. However, echocardiography has its limitat...
Source: The International Journal of Cardiovascular Imaging - July 4, 2018 Category: Radiology Source Type: research

Healing score of the Xinsorb scaffold in the treatment of de novo lesions: 6-month imaging outcomes
The objectives of this study are to assess the healing score (HS) and neointimal thickness of the Xinsorb scaffold, and explore the relationships between the implanted patterns, neointimal thickness, and HS. The Xinsorb bioresorbable sirolimus-eluting scaffold is the first domestically designed and fabricated bioresorbable scaffold in China. The 6-month follow-up found it to be safe and effective in the treatment of single de novo coronary lesions. The Xinsorb scaffolds were implanted in 30 patients with symptomatic ischemic coronary disease. A 6-month follow-up was performed in a subset of 19 patients; the HS and neointim...
Source: The International Journal of Cardiovascular Imaging - July 1, 2018 Category: Radiology Source Type: research

Echocardiographic features of PFOs and paradoxical embolism: a complicated puzzle
AbstractPatent foramen ovale (PFO) is a residual, oblique, slit or tunnel like communication in the atrial septum that persists into adulthood. It is usually an incidental finding with no clinical repercussions. Nevertheless, recent evidence supports the association between the presence of a PFO and a number of clinical conditions, most notably cryptogenic stroke (CS). There is enough evidence that paradoxical embolism is a mechanism which can explain this association. Patient characteristics and certain echocardiography-derived anatomical and hemodynamic features of PFO provide great assistance in estimating the probabili...
Source: The International Journal of Cardiovascular Imaging - June 28, 2018 Category: Radiology Source Type: research

The ventricular residence time distribution derived from 4D flow particle tracing: a novel marker of myocardial dysfunction
Abstract4D flow cardiac magnetic resonance (CMR) imaging allows visualisation of blood flow in the cardiac chambers and great vessels. Post processing of the flow data allows determination of theresidence time distribution (RTD), a novel means of assessing ventricular function, potentially providing additional information beyond ejection fraction. We evaluated the RTD measurement of efficiency of left and right ventricular (LV and RV) blood flow. 16 volunteers and 16 patients with systolic dysfunction (LVEF  
Source: The International Journal of Cardiovascular Imaging - June 27, 2018 Category: Radiology Source Type: research

Computed tomography findings and preoperative risk factors for mortality of total anomalous pulmonary venous connection
AbstractDetailed preoperative imaging of total anomalous pulmonary venous connection (TAPVC) is critical to ensuring adequate surgical planning and preoperative decision making. The purpose of this study was to describe the computed tomography findings of TAPVC and identify morphologic death risk factors. We conducted a retrospective study included 70 patients with TAPVC between May 2014 and June 2017 in Hunan Children ’s Hospital. All available clinical data and computed tomography imaging were reviewed, and survival time was followed-up. Life Tables analysis was used to estimate survival rates. Patient survival was...
Source: The International Journal of Cardiovascular Imaging - June 25, 2018 Category: Radiology Source Type: research

The clinical evaluation of the CADence device in the acoustic detection of coronary artery disease
AbstractThe noninvasive detection of turbulent coronary flow may enable diagnosis of significant coronary artery disease (CAD) using novel sensor and analytic technology. Eligible patients (n  = 1013) with chest pain and CAD risk factors undergoing nuclear stress testing were studied using the CADence (AUM Cardiovascular Inc., Northfield MN) acoustic detection (AD) system. The trial was designed to demonstrate non-inferiority of AD for diagnostic accuracy in detecting significant CAD as compared to an objective performance criteria (sensitivity 83% and specificity 80%, with 15% non-inferiority margins) for nu...
Source: The International Journal of Cardiovascular Imaging - June 23, 2018 Category: Radiology Source Type: research

Cardiovascular imaging 2017 in the International Journal of Cardiovascular Imaging
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - June 23, 2018 Category: Radiology Source Type: research

Pulmonary arterial stiffness assessed by cardiovascular magnetic resonance imaging is a predictor of mild pulmonary arterial hypertension
AbstractEarly detection of mild pulmonary arterial hypertension (PAH) based on clinical evaluation and echocardiography remains quite challenging. In addition to enhanced right ventricular (RV) assessment, cardiac magnetic resonance (CMR) imaging may accurately reflect deleterious remodeling and increased stiffness of the central pulmonary arteries based on pulsatility, or percent change of the PA during the cardiac cycle. The purpose of this study is to assess the utility of measuring PA pulsatility by CMR as a potential early maker in PAH. We hypothesize that pulsatility may help discriminate mild PAH from normal control...
Source: The International Journal of Cardiovascular Imaging - June 22, 2018 Category: Radiology Source Type: research

Evaluation of aortic stiffness by a new simplified 2D speckle tracking analysis
AbstractArterial stiffness is a marker of cardiovascular damage and an independent predictor of major cardiovascular events, usually assessed via Carotid-Femoral Pulse Wave Velocity (cfPWV). The aim of this study was to test the feasibility and usefulness of aortic strain analysis using a simplified transthoracic echocardiography (TTE) speckle-tracking (ST) based method. 60 consecutive patients with normal blood pressure and aortic dimensions underwent TTE and cfPWV evaluation. Strain analysis was performed on the largest section of the ascending aorta (aA) with a dedicated software; three couples of speckles were identifi...
Source: The International Journal of Cardiovascular Imaging - June 21, 2018 Category: Radiology Source Type: research

Clinical efficacy of aspirin with identification of intimal morphology by optical coherence tomography in preventing event recurrence in patients with vasospasm-induced acute coronary syndrome
AbstractUsing optical coherence tomography (OCT), we found that there were morphological differences in the coronary intima between patients with vasospasm-induced acute coronary syndrome (VACS) and those with stable variant angina. We investigated whether aspirin use would protect against chest pain recurrence in patients with VACS. A retrospective cohort study was performed. Patients with ST-segment elevation who were confirmed to have VACS by a provocation test were included. OCT was performed at the index event and when chest pain recurred to assess intimal morphology. Chest pain recurrence was defined as the first rev...
Source: The International Journal of Cardiovascular Imaging - June 19, 2018 Category: Radiology Source Type: research

CMR-guidance of passively tracked endomyocardial biopsy in an in vivo porcine model
This study demonstrates feasibility and safety of CMR-guided and basically targeted EMB with passively-tracked devices. Signal-to-noise ratios of real-time sequences is non-inferior to standard sequences for les ion detection. CMR-guidance may improve diagnostic accuracy of EMB since CMR can detect myocardial-targets under real-time-imaging. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - June 19, 2018 Category: Radiology Source Type: research

Less pronounced reverse left ventricular remodeling in patients with bicuspid aortic stenosis treated with transcatheter aortic valve replacement compared to tricuspid aortic stenosis
AbstractTo compare reverse left ventricular (LV) remodeling after transcatheter aortic valve replacement (TAVR) between patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV). We retrospectively reviewed data of patients with at least two serial echocardiographic follow-ups (1, 3, 6  months and 1 year) post-TAVR. A total of 116 patients were identified. BAV morphology was documented in 67 patients. LV mass index (LVMi) at baseline was not significantly different between the TAV and BAV group (178.0 ± 6.9 vs. 166.3 ± 6.4 g/m2, P  = 0....
Source: The International Journal of Cardiovascular Imaging - June 18, 2018 Category: Radiology Source Type: research