Automatic coronary blood flow computation: validation in quantitative flow ratio from coronary angiography
AbstractTo assess a novel approach for automatic flow velocity computation in deriving quantitative flow ratio (QFR) from coronary angiography. QFR is a novel approach for assessment of functional significance of coronary artery stenosis without using pressure wire and induced hyperemia. Patient-specific coronary flow is estimated semi-automatically by frame count method, which is subjective and inconvenient in the workflow of QFR analysis. The vascular structures were automatically delineated from coronary angiogram. Subsequently, the centerline of the interrogated vessel was extracted from the delineated lumen on each im...
Source: The International Journal of Cardiovascular Imaging - December 8, 2018 Category: Radiology Source Type: research

Imaging and Surgical Treatment of Primary Pulmonary Artery Sarcoma
AbstractPrimary pulmonary artery sarcoma is a rare tumor originating from the pulmonary artery tree. Given the low incidence, few centers have reported on more than a handful of cases. Because of its rarity it is also commonly misdiagnosed as pulmonary embolism. Multi-modality diagnostic imaging and recognition of specific imaging characteristics along with a high index of suspicion is required to make the correct diagnosis and expedite treatment. The primary imaging modality for most cardiac tumors such as primary pulmonary artery sarcoma is now MRI. It provides superb spatial resolution as well as functional assessment o...
Source: The International Journal of Cardiovascular Imaging - December 8, 2018 Category: Radiology Source Type: research

Insights into functional mitral regurgitation using the average pixel intensity method
AbstractPreviously we introduced and validated the average pixel intensity (API) method for grading mitral regurgitation (MR) in a heterogeneous MR population. We now investigated the feasibility and added value of the API method more specifically in patients with functional MR (FMR). We consecutively enrolled 283 patients with pure FMR. Transthoracic echocardiography was performed and MR was assessed using the API method and guideline-recommended parameters, including color Doppler, vena contracta width (VCW) and proximal isovelocity surface area (PISA)-based methods. The API method had an applicability of 98% in this FMR...
Source: The International Journal of Cardiovascular Imaging - December 3, 2018 Category: Radiology Source Type: research

Can stress echocardiography identify patients who will benefit from percutaneous mitral valve repair?
AbstractThe aim of the current study was to investigate whether stress echocardiography improves selection of patients who might have clinical benefit from percutaneous mitral valve repair with the MitraClip. In total, 39 patients selected for MitraClip implantation underwent preprocedural low-dose stress (dobutamine or handgrip) echocardiography from which stroke volume, ejection fraction and MR grade were measured. Outcome after MitraClip implantation was determined by New York Heart Association classification and Quality of Life questionnaires. Clinical benefit from MitraClip treatment was defined as survival and NYHA c...
Source: The International Journal of Cardiovascular Imaging - November 29, 2018 Category: Radiology Source Type: research

Left atrial functional response after a marathon in healthy amateur volunteers
AbstractMiddle-aged marathon runners have an increased risk of developing atrial fibrillation (AF). A previous study described that repetitive marathon running was associated with left atrial (LA) dysfunction. However, whether this change is common in marathon runners and which runners are at risk of LA dysfunction remain unknown. The purpose of this study was to determine which factors could predict LA dysfunction. We prospectively examined 12 healthy amateur volunteers (9 males, 31  ± 8 years old) who participated in a full marathon. All echocardiographic measurements and speckle-tracking echoca...
Source: The International Journal of Cardiovascular Imaging - November 23, 2018 Category: Radiology Source Type: research

Cardiac T2 star mapping: standardized inline analysis of long and short axis at three identical 1.5  T MRI scanners
AbstractT2 star mapping can be applied for in vivo cardiac iron quantification. Current recommendations of imaging acquisition, post-processing and interpretation of normal values are based on old scanner types and in house software packages. A standardized comparison of short (SAX) and long axis (LAX) segments using commercially available software packages and modern scanners is lacking. To provide a standardized comparison of T2 star time values in SAX and LAX and to investigate intersegmental, interregional and inter-level comparison and the interscanner reproducibility. 84 cardiac MRIs in 28 healthy volunteers were per...
Source: The International Journal of Cardiovascular Imaging - November 21, 2018 Category: Radiology Source Type: research

Drop-off in positivity rate of stress echocardiography based on regional wall motion abnormalities over the last three decades
AbstractPrevious studies have suggested a decline in positivity of stress cardiac imaging based on regional wall motion abnormalities (RWMA). To assess the rate of RWMA positivity of stress echocardiography (SE) over 3 decades in the same primary care SE lab. We retrospectively assessed the rate of SE positivity in 7626 SE tests (dipyridamole in 5053, dobutamine in 2496, exercise in 77) in consecutive patients with known or suspected coronary artery disease and /or heart failure who performed SE in a primary care referral center from April 1991 to May 2018. Starting April 2005, SE based on RWMA was complemented by assessme...
Source: The International Journal of Cardiovascular Imaging - November 20, 2018 Category: Radiology Source Type: research

Coronary computed tomography angiography (CCTA) in patients with suspected stable coronary artery disease (CAD): diagnostic impact and clinical consequences in the German Cardiac CT Registry depending on stress test results
AbstractTo evaluate diagnostic impact of clinical use of coronary computed tomography angiography (CCTA) in patients with suspected stable coronary artery disease (CAD) and its consequences in daily practice for patient management, depending on stress test results in daily practice. Between 2009 and 2014 of a total population of 1352 patients of the German Cardiac Computed Tomography (CT) Registry who had previously undergone stress tests, CCTA visualizations were carried out on the coronary arteries with suspected stable CAD. Patients were divided into three groups according to stress test results: Group 1 with inconclusi...
Source: The International Journal of Cardiovascular Imaging - November 19, 2018 Category: Radiology Source Type: research

Culotte versus the novel nano-crush technique for unprotected complex bifurcation left main stenting: difference in procedural time, contrast volume and X-ray exposure and 3-years outcomes
AbstractTo assess the procedural performance and 3-years outcomes of unprotected complex bifurcation Left Main (LM) stenting using either Culotte or the novel nano-crush techniques, consisting in the use of two ultra-thin strut stents with a 1-ring stent crushed into the LM. We analysed the records of patients with complex distal/bifurcation LM disease and contraindications and/or refusal of bypass surgery, who from 1 January 2014 to 1 November 2017, received at operators ’ discretion LM double stenting by means of nano-crush technique using Orsiro (Biotronik Inc, Bulack, Switzerland) or Onyx (Medtronic Inc, Galway, ...
Source: The International Journal of Cardiovascular Imaging - November 16, 2018 Category: Radiology Source Type: research

Multi-parametric “on board” evaluation of right ventricular function using three-dimensional echocardiography: feasibility and comparison to traditional two-and three dimensional echocardiographic measurements
AbstractThree-dimensional echocardiographic (3DE) of right ventricle (RV) has been validated in many clinical settings. However, the necessity of complicated and off –line dedicated software has reduced its diffusion. A new simplified “on board” 3DE software (OB) has been developed to obtain RV volumes and ejection fraction (EF) together with several conventional parameters automatically derived from 3DE: tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), longitudinal strain (LS). Aims of this study were to evaluate feasibility and accuracy of OB RV analysis. A complete 2DE ...
Source: The International Journal of Cardiovascular Imaging - November 15, 2018 Category: Radiology Source Type: research

Effect of image quality on accuracy of two-dimensional strain echocardiography for diagnosing ischemic chest pain: a 2DSPER multicenter trial substudy
AbstractFew data exist regarding the effect of image quality on measurements of two-dimensional longitudinal strain (2DLS). In the 2DLS for Diagnosing Chest Pain in the Emergency Room (2DSPER) multicenter study, 2DLS was not useful for ruling out acute coronary syndromes (ACS) in the emergency department (ED). The aim of this substudy was to determine the effect of 2D image quality on the diagnostic accuracy of 2DLS for ACS. We reviewed apical views used for 2DLS analysis in all 605 patients included in the 2DSPER study. Studies with the best image quality (HighQ, n  = 177), were compared to the lower quality...
Source: The International Journal of Cardiovascular Imaging - November 14, 2018 Category: Radiology Source Type: research

Post-implantation shear stress assessment: an emerging tool for differentiation of bioresorbable scaffolds
AbstractOptical coherence tomography based computational flow dynamic (CFD) modeling provides detailed information about the local flow behavior in stented/scaffolded vessel segments. Our aim is to investigate the in-vivo effect of strut thickness and strut protrusion on endothelial wall shear stress (ESS) distribution in ArterioSorb Absorbable Drug-Eluting Scaffold (ArterioSorb) and Absorb everolimus-eluting Bioresorbable Vascular Scaffold (Absorb) devices that struts with similar morphology (quadratic structure) but different thickness. In three animals, six coronary arteries were treated with ArterioSorb. At different s...
Source: The International Journal of Cardiovascular Imaging - November 13, 2018 Category: Radiology Source Type: research

Adenosine triphosphate (ATP) and adenosine cause similar vasodilator effect in patients undergoing stress perfusion cardiac magnetic resonance imaging
AbstractTo evaluate the vasodilator effect of adenosine triphosphate (ATP) compared with adenosine in stress perfusion cardiac magnetic resonance (CMR) examinations. A total of thirty-three patients underwent clinically indicated stress/rest perfusion CMR examination following intravenous injection of a total dose of 0.2  mmol/kg of gadobutrol. Individuals were randomly assigned to ATP (160 mcg/kg/min) or adenosine (140 mcg/kg/min). The vasodilator effect of both drugs was analyzed by comparing differences in heart rate, symptoms during stress, and semiquantitative myocardial and splenic perfusion parameters...
Source: The International Journal of Cardiovascular Imaging - November 13, 2018 Category: Radiology Source Type: research

Assessment of peri-device leaks after interventional left atrial appendage closure using standardized imaging by cardiac computed tomography angiography
AbstractCardiac computed tomography angiography  (cCTA) has recently been proposed for evaluation of successful interventional left atrial appendage closure (LAA/LAAC). This prospective longitudinal observational study aims to assess this proposal by applying a standardized imaging protocol to detect and quantify peri-device leaks (PDL) after L AAC. cCTA datasets of consecutive patients 6 months after successful LAAC were acquired on a third generation dual-source computed tomography system and reconstructed with a slice thickness of 0.5 mm. The standardized multi-planar reconstruction LAA occluder...
Source: The International Journal of Cardiovascular Imaging - November 12, 2018 Category: Radiology Source Type: research

The added value of right ventricular longitudinal strain in patients with chronic thromboembolic pulmonary hypertension
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 12, 2018 Category: Radiology Source Type: research

Assessment of left atrial remodeling in paroxysmal atrial fibrillation with speckle tracking echocardiography: a study with an electrophysiological mapping system
This study aimed to evaluate left atrial (LA) remodeling and fibrosis in paroxysmal atrial fibrillation (AF)  using speckle tracking echocardiography (STE) based on the findings with radiofrequency catheter ablation (RFCA) so as to predict atrial remodeling prior to ablation. A total of 40 patients with paroxysmal AF were enrolled and divided into two groups based on LA bipolar voltage detected during RFC A: those with low-voltage zone (LVZ) (LV group,n = 19) and those without LVZ (non-LV group,n = 21). The segmental and global LA reservoir, conduit and contractile strain (εs, &epsi...
Source: The International Journal of Cardiovascular Imaging - November 9, 2018 Category: Radiology Source Type: research

Letter by Garcia A, et al. regarding article “The clinical evaluation of the CADence device in the acoustic detection of coronary artery disease”
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 9, 2018 Category: Radiology Source Type: research

Early diastolic strain rate measurements by cardiac MRI in breast cancer patients treated with trastuzumab: a longitudinal study
AbstractWe evaluated temporal changes in early diastolic strain rates by cardiovascular magnetic resonance (CMR) as an early detector of trastuzumab-induced ventricular dysfunction. We conducted a prospective, multi-centre, longitudinal observational study of 41 trastuzumab-treated breast cancer women who underwent serial CMR (baseline, 6, 12, and 18  months). Two blinded readers independently measured left ventricular ejection fraction (LVEF), peak systolic strain parameters (global longitudinal strain [GLS] and global circumferential strain [GCS]), and early diastolic strain rate parameters (global longitudinal dias...
Source: The International Journal of Cardiovascular Imaging - November 2, 2018 Category: Radiology Source Type: research

First Presentation of Integration of Intravascular Optical Coherence Tomography and Computational Fractional Flow Reserve
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 2, 2018 Category: Radiology Source Type: research

Pulmonary arteriovenous malformations
AbstractPulmonary arteriovenous malformation, a condition most commonly associated with hereditary hemorrhagic telangiectasia, is an abnormal communication between the pulmonary artery and pulmonary vein without an intervening capillary communication. Although asymptomatic in ~  50% individuals, it can present with the dreaded complications of stroke or intracranial abscess in high-risk individuals including pregnant women, if untreated. The mainstay of treatment is now endovascular embolization of the feeding artery which can alleviate the symptoms and prevent these com plications. In this review, we describe the p...
Source: The International Journal of Cardiovascular Imaging - November 1, 2018 Category: Radiology Source Type: research

A propensity score matched valuation on feasibility of low frame rate fluoroscopy during primary percutaneous coronary intervention for patients with STEMI
AbstractThe present study aimed to evaluate the feasibility of low frame rate fluoroscopy during primary percutaneous coronary intervention (PPCI) for patients with acute ST elevation myocardial infarction (STEMI). From January 2016 to December 2017, 165 consecutive patients with STEMI who underwent PPCI were retrospectively divided into two groups: the 7.5-frame group (fluoroscopy at 7.5  frames/s) and the 15-frame group (fluoroscopy at 15 frames/s), according to the frame rate of fluoroscopy used in their treatment. Reduction of radiation and safety of fluoroscopy at 7.5 frames/s were compared by a method ...
Source: The International Journal of Cardiovascular Imaging - November 1, 2018 Category: Radiology Source Type: research

Extreme negative remodeling of septal left anterior descending branch masquerading as a bifurcation lesion
We report a case of severe negative remodelling at the ostium of septal LAD artery. We deferred stenting to avoid the risk of rupture of the vessel and stent fracture (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 31, 2018 Category: Radiology Source Type: research

Cardiac magnetic resonance based deformation imaging: role of feature tracking in athletes with suspected arrhythmogenic right ventricular cardiomyopathy
AbstractBoth, arrhythmogenic right ventricular cardiomyopathy (ARVC) and regular training are associated with right ventricular (RV) remodelling. Cardiac magnetic resonance (CMR) is given an important role in the diagnosis of ARVC in current task force criteria (TFC), however, they contain no cut-off values for athletes. We aimed to confirm the added value of feature tracking and to provide new cut-off values to differentiate between ARVC and athlete ’s heart. Healthy athletes with training of minimal 15 h/week (n = 34), patients with definite ARVC (n = 34) and highly trained athletes...
Source: The International Journal of Cardiovascular Imaging - October 31, 2018 Category: Radiology Source Type: research

99mTc-HMPAO-labeled leukocyte SPECT/CT and transthoracic echocardiography diagnostic value in infective endocarditis
AbstractInfective endocarditis (IE) is a life-threatening disease, establishing a diagnosis is often challenging. The aim of this prospective study was to evaluate and compare the diagnostic performance of the combined use of single photon emission tomography and computed tomography with technetium99m-hexamethylpropyleneamineoxime —labeled leukocytes (99mTc-HMPAO-SPECT/CT) with transthoracic echocardiography (TTE) in patients with suspected IE. We enrolled 40 consecutive patients (12 females, 28 males, mean age: 58.6 ± 18) with suspected IE in the years 2015–2016. All patients underwent cli...
Source: The International Journal of Cardiovascular Imaging - October 31, 2018 Category: Radiology Source Type: research

Influence of age and sex on left ventricular diastolic strain analysis
AbstractSpeckle tracking analysis (STE) of the left ventricle offers a new method to assess left ventricular (LV) diastolic function. LV diastolic strain measurements offer a non-invasive, global and direct measure of LV diastolic function. However, there is little data on normal values and the influence of anthropomorphic factors which is crucial in clinical practice for new techniques. The aims of this study were to formulate reference values for LV diastolic strain rate, elucidate effects of age and sex on LV diastolic strain analysis and compare STE measurements with conventional LV diastolic measurements. One-hundred-...
Source: The International Journal of Cardiovascular Imaging - October 30, 2018 Category: Radiology Source Type: research

New echocardiographic method for chronic aortic regurgitation: diastolic retrograde ratio in the descending aorta by vector flow mapping
AbstractThe aim of this study was to evaluate the diagnostic performance of the diastolic retrograde ratio in the descending aorta in patients with aortic regurgitation (AR) by vector flow mapping (VFM). Conventional Doppler echocardiography and VFM were performed in 73 patients with various degrees of AR and 40 controls. AR severity was assessed by an expert using the currently recommended integrative approach, including vena contracta width (VCW), jet width to left ventricular outflow tract (jet width/LVOT) ratio, and effective regurgitant orifice area (EROA). The retrograde ratio, derived as the quotient of backward flo...
Source: The International Journal of Cardiovascular Imaging - October 30, 2018 Category: Radiology Source Type: research

Extended cardiac magnetic resonance imaging with retained temporary transmyocardial pacing lead
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 29, 2018 Category: Radiology Source Type: research

Native T1 mapping to detect extent of acute and chronic myocardial infarction: comparison with late gadolinium enhancement technique
AbstractInvestigate whether native-T1 mapping can assess the transmural extent of myocardial infarction (TEI) thereby differentiating viable from non-viable myocardium without the use of gadolinium-contrast in both acute and chronic myocardial infarction (aMI and cMI). Sixty patients (30 cMI  >  1 year and 30 aMI day 2 STEMI) and 20 healthy-controls underwent 1.5 T CMR to assess left ventricular function (cine), native-T1 mapping (MOLLI sequence 5(3)3, motion-corrected) and the presence and TEI from late gadolinium enhancement (LGE) images. Segments with TEI >  75% was considered non-viabl...
Source: The International Journal of Cardiovascular Imaging - October 24, 2018 Category: Radiology Source Type: research

17 β-estradiol preserves right ventricular function in rats with pulmonary arterial hypertension: an echocardiographic and histochemical study
AbstractPulmonary arterial hypertension (PAH) is more prevalent in females. Paradoxically, female patients have better right ventricular (RV) function and higher survival rates than males. However, the effects of 17 β-estradiol (E2) on RV function in PAH has not been studied. Twenty-four male rats were exposed to monocrotaline (MCT) to induce experimental PAH, while treated with E2 or vehicle respectively. Together with eight control rats, thirty-two rats were examined by echocardiography 4 weeks after drug a dministration. Echocardiographic measurement of RV function included: tricuspid annular plane systolic ex...
Source: The International Journal of Cardiovascular Imaging - October 22, 2018 Category: Radiology Source Type: research

Proteinuria is an independent predictor of rapid progression of mild to moderate aortic stenosis in patients with preserved renal function
AbstractAlthough proteinuria is a well-known risk factor for cardiovascular disease, its relationship with the progression of aortic stenosis (AS) has not been established. Our aim was to investigate the relationship between proteinuria (detected by urine dipstick test) and AS progression (assessed by the annualized reduction rate of aortic valve area [AVA]). A total of 460 patients with mild to moderate AS (defined by a peak velocity of 2.0 –4.0 m/s) without end-stage renal disease who underwent two echocardiograms at least 3 months apart were included. The progression of AS was significantly faster in pat...
Source: The International Journal of Cardiovascular Imaging - October 20, 2018 Category: Radiology Source Type: research

An unusual cause of pulmonary outflow obstruction: IgG4 deposition disease-MRI observations
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 19, 2018 Category: Radiology Source Type: research

Left atrial longitudinal strain in dilated cardiomyopathy patients: is there a discrimination threshold for atrial fibrillation?
AbstractTo determine the left atrial longitudinal strain discrimination threshold of atrial fibrillation (AF) in patients with dilated cardiomyopathy (DCM). A total of 100 DCM patients and LVEF  
Source: The International Journal of Cardiovascular Imaging - October 19, 2018 Category: Radiology Source Type: research

Moving into the next era of PET myocardial perfusion imaging: introduction of novel 18 F-labeled tracers
AbstractThe heart failure epidemic continues to rise with coronary artery disease as one of its main causes. Novel concepts for risk stratification to guide the referring cardiologist towards revascularization procedures are of significant value. Myocardial perfusion imaging using single-photon emission computed tomography (SPECT) agents has demonstrated high accuracy for the detection of clinically relevant stenoses. With positron emission tomography (PET) becoming more widely available, mainly due to its diagnostic performance in oncology, perfusion imaging with that modality is more practical than in the past and overco...
Source: The International Journal of Cardiovascular Imaging - October 17, 2018 Category: Radiology Source Type: research

Epicardial fat amount is associated with the magnitude of left ventricular remodeling in aortic stenosis
AbstractBoth genetic and environmental factors interact to control left ventricular (LV) remodeling in the context of aortic stenosis (AS). Epicardial adipose tissue (EAT) is a specific visceral adipose tissue with paracrine properties in close contact with the myocardium. We sought to assess determinants of EAT amount and its association with the magnitude and pattern of LV remodeling in patients suffering from severe AS. Between January 2014 and September 2017, we prospectively explored consecutive patients referred to our Heart Valve Center for SAVR presenting with severe AS and normal left ventricular ejection fraction...
Source: The International Journal of Cardiovascular Imaging - October 17, 2018 Category: Radiology Source Type: research

Relationships of high cardiac output with ventricular morphology, myocardial energetics, and energy costs in hemodialysis patients with preserved ejection fraction
AbstractHemodialysis patients have conditions that increase cardiac output (CO), including arteriovenous fistula, fluid retention, vasodilator use, and anemia. We sought to determine the relationships between these factors and CO and to evaluate the effects of the high-output states on ventricular morphology, function, and myocardial energetics in hemodialysis patients, using noninvasive load-insensitive indices. Cardiovascular function was assessed in hemodialysis patients with high output [ejection fraction  ≥ 50%, cardiac index (CI) >  3.5 L/min/m2, n  = 30], those wi...
Source: The International Journal of Cardiovascular Imaging - October 16, 2018 Category: Radiology Source Type: research

Impact of tissue protrusion after coronary stenting in patients with ST-segment elevation myocardial infarction
AbstractClinical impact of tissue protrusion (TP) after coronary stenting is still controversial, especially in patients with ST-segment elevation myocardial infarction (STEMI). A total of 104 STEMI patients without previous MI who underwent primary percutaneous coronary intervention (PCI) under intravascular ultrasound (IVUS)-guidance were included. Post-stenting grayscale IVUS analysis was performed, and the patients were classified according to the presence or absence of post-stenting TP on IVUS. Coronary angiography and single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) with99mTc tetrof...
Source: The International Journal of Cardiovascular Imaging - October 16, 2018 Category: Radiology Source Type: research

Diffusion-weighted MR in chronic periaortitis, a new technique has entered the clinical arena
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 15, 2018 Category: Radiology Source Type: research

Crowdsourcing consensus: proposal of a novel method for assessing accuracy in echocardiography interpretation
We examined the utility of crowd-sourcing a “majority-vote” consensus as an alternative ‘gold standard’ against which to evaluate the accuracy of an individual echocardiographer’s interpretation of stress echocardiography studies. Participants independently interpreted baseline and post-exercise stress echocardiographic images of ca ses that had undergone follow up CA within 3 months of the stress echo in two surveys, 2 years apart. We examined the agreement of consensus on survey (survey participant response (>  60%) for one decision) with the stress echocardiography clini...
Source: The International Journal of Cardiovascular Imaging - October 15, 2018 Category: Radiology Source Type: research

Congenital pseudoaneurysm of the mitral-aortic intervalvular fibrosa with a 5 years ’ follow up
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 8, 2018 Category: Radiology Source Type: research

Successful radiofrequency catheter ablation of atrial fibrillation is associated with improvement in left ventricular energy loss and mechanics abnormalities
AbstractDissipative energy loss (EL), an index of inefficient blood flow, has not been studied in patients with atrial fibrillation (AF). We therefore assessed the effect of AF and of successful catheter ablation on left ventricular (LV) EL and global longitudinal strain (GLS) to explore the effect of inefficient blood flow on LV remodeling. In 53 patients undergoing catheter ablation for AF (AF group), LV EL (in mW/m) was evaluated by vector flow mapping (VFM) during systole (ELsys), early diastole (ELed) and atrial contraction phase (ELac), and GLS was calculated by two-dimensional tissue tracking (2DTT). Of the 53 patie...
Source: The International Journal of Cardiovascular Imaging - October 6, 2018 Category: Radiology Source Type: research

Low CT temporal sampling rates result in a substantial underestimation of myocardial blood flow measurements
AbstractThe purpose of this study was  to evaluate the effect of temporal sampling rate in dynamic CT myocardial perfusion imaging (CTMPI) on myocardial blood flow (MBF). Dynamic perfusion CT underestimates myocardial blood flow compared to PET and SPECT values. For accurate quantitative analysis of myocardial perfusion with dynamic pe rfusion CT a stable calibrated HU measurement of MBF is essential. Three porcine hearts were perfused using an ex-vivo Langendorff model. Hemodynamic parameters were monitored. Dynamic CTMPI was performed using third generation dual source CT at 70 kVp and 230–350 mAs/ro...
Source: The International Journal of Cardiovascular Imaging - October 4, 2018 Category: Radiology Source Type: research

Flow convergence visualized in mitral regurgitation with spontaneous echo contrast
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 4, 2018 Category: Radiology Source Type: research

Low CT temporal sampling rates result in a substantial underestimation of myocardial blood flow measurements
AbstractThe purpose of this study was  to evaluate the effect of temporal sampling rate in dynamic CT myocardial perfusion imaging (CTMPI) on myocardial blood flow (MBF). Dynamic perfusion CT underestimates myocardial blood flow compared to PET and SPECT values. For accurate quantitative analysis of myocardial perfusion with dynamic pe rfusion CT a stable calibrated HU measurement of MBF is essential. Three porcine hearts were perfused using an ex-vivo Langendorff model. Hemodynamic parameters were monitored. Dynamic CTMPI was performed using third generation dual source CT at 70 kVp and 230–350 mAs/ro...
Source: The International Journal of Cardiovascular Imaging - October 4, 2018 Category: Radiology Source Type: research

Flow convergence visualized in mitral regurgitation with spontaneous echo contrast
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 4, 2018 Category: Radiology Source Type: research

Correlation of FFR-derived from CT and stress perfusion CMR with invasive FFR in intermediate-grade coronary artery stenosis
AbstractOnly one-third of intermediate-grade coronary artery stenosis (i.e. 40 –70% diameter narrowing) causes myocardial ischemia, requiring most often additional invasive work-up with invasive fractional flow reserve (FFR). To evaluate the correlations between FFR estimates derived from computed tomography (FFRCT) and adenosine perfusion cardiac magnetic resonance (CMR) with invasive FFR in intermediate-grade stenosis. Thirty-seven patients (mean age 61  ± 9 years; 25 men) who underwent adenosine perfusion CMR, quantitative coronary angiography and FFR in the work-up for intermediate-grade sten...
Source: The International Journal of Cardiovascular Imaging - October 3, 2018 Category: Radiology Source Type: research

Left atrial myocardial dysfunction after chronic abuse of anabolic androgenic steroids: a speckle tracking echocardiography analysis
AbstractAnabolic –androgenic steroids (AAS) are used by power athletes to improve performance. However, the real effects of the chronic consumption of AAS on cardiovascular structures are subjects of intense debate. To detect by speckle tracking echocardiography (STE) underlying left atrial (LA) dysfunction in ath letes abusing AAS and assess possible correlation between LA myocardial function and exercise capacity during cardiopulmonary stress test. 65 top-level competitive bodybuilders were selected (45 males), including 35 athletes misusing AAS for at least 5 years (users), 30 anabolic-free bodybuilders (n on-user...
Source: The International Journal of Cardiovascular Imaging - October 1, 2018 Category: Radiology Source Type: research

Brief cardiovascular imaging with pocket-size ultrasound devices improves the accuracy of the initial assessment of suspected pulmonary embolism
AbstractPulmonary embolism onset is frequently neglected due to the non-specific character of its symptoms. Pocket-size imaging devices (PSID) present an opportunity to implement imaging diagnostics into conventional physical examination. The aim of this study was to test the hypothesis that supplementation of the initial bedside assessment of patients with suspected pulmonary embolism (PE) with four-point compression venous ultrasonography (CUS) and right ventricular size assessment with the use of PSID equipped with dual probe could positively influence the accuracy of clinical predictions. A single-centre, prospective a...
Source: The International Journal of Cardiovascular Imaging - October 1, 2018 Category: Radiology Source Type: research

Electrocardiography based prediction of hypertrophy pattern and fibrosis amount in hypertrophic cardiomyopathy: comparative study with cardiac magnetic resonance imaging
AbstractAlthough, cardiac magnetic resonance imaging (CMR) is a gold standard for risk stratification of hypertrophic cardiomyopathy (HCM), is limited in some situations. We sought to evaluate the predictive power of quantitative electrocardiography in assessing hypertrophy pattern and fibrosis in HCM. Eighty-eight patients with HCM were studied. Voltage of R –S–T waves, number of fragmented QRS (fQRS) complexes, and T wave morphology were measured by 12-lead electrocardiography. Sixteen segmental thickness, late gadolinium enhancement (LGE), native T1, extracellular volume fraction (ECV), and T2, left ventricu...
Source: The International Journal of Cardiovascular Imaging - October 1, 2018 Category: Radiology Source Type: research

Findings on 3D speckle tracking echocardiography in asymptomatic methamphetamine abusers
AbstractTo detect potential cardiac abnormalities in asymptomatic methamphetamine abusers using three-dimensional speckle tracking echocardiography (3D STE). Fifty-three male methamphetamine abusers, free of cardiac symptoms/signs, were enrolled in this study. A control group of 53 age-matched male normal subjects was studied for comparison. Standard 3D, flow and tissue Doppler echo with measurements of left ventricular end-diastolic volume (LVEDV), end-systolic volume (LVESV), ejection fraction (LVEF), the ratio of the early to late diastolic transmitral filling velocity (E/A), the ratio of the early diastolic transmitral...
Source: The International Journal of Cardiovascular Imaging - October 1, 2018 Category: Radiology Source Type: research