Stent fracture and longitudinal compression detected on coronary CT angiography in the first- and new-generation drug-eluting stents
Abstract To evaluated prevalence and clinical implication of stent fracture and longitudinal compression in first- and new-generation drug-eluting stents (DES) using coronary computed tomography angiography (CCTA). The incidence of stent fracture and longitudinal compression were compared between first- and new-generation DES in 374 patients who underwent coronary stenting using DES and follow-up CCTA due to recurrent angina. 235 and 139 patients received 322 first- and 213 new-generation DES, respectively. The crude per-stent incidence of longitudinal compression (6.1 vs. 0.3 %, p 
Source: The International Journal of Cardiovascular Imaging - October 26, 2015 Category: Radiology Source Type: research

Cardiac CTA for evaluation of cardiac function in patients with congenital heart disease: the good, the bad and the ugly
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 26, 2015 Category: Radiology Source Type: research

Qualitative grading of aortic regurgitation: a pilot study comparing CMR 4D flow and echocardiography
Abstract Over the past 10 years there has been intense research in the development of volumetric visualization of intracardiac flow by cardiac magnetic resonance (CMR). This volumetric time resolved technique called CMR 4D flow imaging has several advantages over standard CMR. It offers anatomical, functional and flow information in a single free-breathing, ten-minute acquisition. However, the data obtained is large and its processing requires dedicated software. We evaluated a cloud-based application package that combines volumetric data correction and visualization of CMR 4D flow data, and assessed its accu...
Source: The International Journal of Cardiovascular Imaging - October 24, 2015 Category: Radiology Source Type: research

Segmental assessments of coronary plaque morphology and composition by virtual histology intravascular ultrasound and fractional flow reserve
Abstract Fractional flow reserve (FFR) is an index for identifying functionally significant stenotic lesions. A FFR value of ≤0.75 is considered clinically significant and indicative of physiological ischemia. Focal lesions with 30–80 % stenosis by angiography with lesion lengths of less than 20 mm were selected from left anterior descending arteries of 74 patients. The analysis for the total lesion was processed first, and then each lesion was divided into three segments to assess the each segment. Data on plaque geometry and composition of two FFR groups, FFR ≤ 0.75 and FFR&nb...
Source: The International Journal of Cardiovascular Imaging - October 23, 2015 Category: Radiology Source Type: research

Automatic aortic root landmark detection in CTA images for preprocedural planning of transcatheter aortic valve implantation
Abstract Transcatheter aortic valve implantation is currently a well-established minimal invasive treatment option for patients with severe aortic valve stenosis. CT Angiography is used for the pre-operative planning and sizing of the prosthesis. To reduce the inconsistency in sizing due to interobserver variability, we introduce and evaluate an automatic aortic root landmarks detection method to determine the sizing parameters. The proposed algorithm detects the sinotubular junction, two coronary ostia, and three valvular hinge points on a segmented aortic root surface. Using these aortic root landmarks, the ...
Source: The International Journal of Cardiovascular Imaging - October 23, 2015 Category: Radiology Source Type: research

Blood flow characteristics in the ascending aorta after TAVI compared to surgical aortic valve replacement
Abstract Ascending aortic blood flow characteristics are altered after aortic valve surgery, but the effect of transcatheter aortic valve implantation (TAVI) is unknown. Abnormal flow may be associated with aortic and cardiac remodeling. We analyzed blood flow characteristics in the ascending aorta after TAVI in comparison to conventional stented aortic bioprostheses (AVR) and healthy subjects using time-resolved three-dimensional flow-sensitive cardiovascular magnetic resonance imaging (4D-flow MRI). Seventeen patients with TAVI (Edwards Sapien XT), 12 with AVR and 9 healthy controls underwent 4D-flow MRI of the ...
Source: The International Journal of Cardiovascular Imaging - October 22, 2015 Category: Radiology Source Type: research

P-wave morphology is unaffected by training-induced biatrial dilatation: a prospective, longitudinal study in healthy athletes
This study aimed to prospectively investigate whether exercise-induced increase in biatrial size corresponds to electrical changes on 12-lead ECG. Thirty-five athletes were evaluated at the beginning of the training and after 6 months by ECG and standard and speckle-tracking echocardiography. Twenty-three sedentary subjects served as controls. Athletes had greater left atrial (LA) and right atrial (RA) size compared with controls (20.7 ± 4.7 vs. 27.1 ± 6.6 and 17.3 ± 3.8 vs. 23.4 ± 6.3 mL/m2, respectively, p 
Source: The International Journal of Cardiovascular Imaging - October 17, 2015 Category: Radiology Source Type: research

Multi-institutional evaluation of the indications and radiation dose of functional cardiovascular computed tomography (CCT) imaging in congenital heart disease
Abstract Ventricular volumes and ejection fraction are often used in clinical decision making in patients with congenital heart disease (CHD). The referral diagnosis, radiation exposure and image quality of functional cardiac computed tomography (CT) in a relatively large cohort of patients of CHD has not been reported. This is a retrospective evaluation of functional CT studies performed in CHD patients from three institutions (1/2007–3/2013). Patient and scanner characteristics, radiation dose estimates and image quality were compared. Two hundred ninety-eight functional CT studies were evaluated. The most...
Source: The International Journal of Cardiovascular Imaging - October 16, 2015 Category: Radiology Source Type: research

Increased native T1-values at the interventricular insertion regions in precapillary pulmonary hypertension
Abstract Cardiac magnetic resonance imaging of the pressure overloaded right ventricle (RV) of precapillary pulmonary hypertension (PH) patients, exhibits late gadolinium enhancement at the interventricular insertion regions, a phenomenon which has been linked to focal fibrosis. Native T1-mapping is an alternative technique to characterize myocardium and has the advantage of not requiring the use of contrast agents. The aim of this study was to characterize the myocardium of idiopathic pulmonary arterial hypertension (IPAH), systemic scleroderma related PH (PAH-Ssc) and chronic thromboembolic PH (CTEPH) patien...
Source: The International Journal of Cardiovascular Imaging - October 16, 2015 Category: Radiology Source Type: research

Left atrial strain after maximal exercise in competitive waterpolo players
Abstract Left atrial (LA) function is a determinant of left ventricular (LV) filling. It carries out three main functions: reservoir, conduit, contractile. Aim of this study was to evaluate the role of LA and its deformation properties on LV filling at rest (R) and immediately after a maximal exercise (ME) through the speckle tracking echocardiography. Population enrolled was composed by 23 water polo athletes who performed a ME of six repeats of 100 m freestyle swim sets. At ME peak atrial longitudinal strain was reduced but all strain rate (SR) parameters increased, respectively positive peak SR at reservoi...
Source: The International Journal of Cardiovascular Imaging - October 15, 2015 Category: Radiology Source Type: research

Dyspnea predicts mortality among patients undergoing coronary computed tomographic angiography
We examined features associated with incident mortality risk among individuals undergoing coronary computed tomographic angiography (CCTA) presenting with dyspnea, typical angina, and neither of these symptoms. 1147 consecutive individuals without known CAD (mean 61 years, 61.6 % men) undergoing CCTA comprised the study population 132 with dyspnea, 218 with typical angina, and 797 without dyspnea or typical angina (reference group). Mortality risk in relation to dyspnea or typical angina was evaluated with multivariable Cox proportional hazards models compared to reference. In addition, the prognosis associated w...
Source: The International Journal of Cardiovascular Imaging - October 14, 2015 Category: Radiology Source Type: research

The association of hemoglobin A1c and high risk plaque and plaque extent assessed by coronary computed tomography angiography
The objective of this study was to investigate the relationship of Hemoglobin A1c (HbA1c) and plaque characteristics including high risk plaque and plaque extent. We retrospectively examined 1079 consecutive coronary computed tomography (CT) angiography scans and the HbA1c results. We divided the patients into four groups by the HbA1c status: non-diabetic, ≤6.0; borderline, 6.1–6.4; diabetic low, 6.5–7.1; diabetic high,>7.1. We determined segment involvement score>4 as extensive disease. High risk plaque was defined as two feature positive (FP) plaque which consists of positive remodeling (remodel...
Source: The International Journal of Cardiovascular Imaging - October 13, 2015 Category: Radiology Source Type: research

Prognostic value of coronary CT angiography in diabetic patients: a 5-year follow up study
This study evaluates prognostic value of coronary computed tomography angiography (CCTA) for long-term outcome to predict cardiac events in oligosymptomatic diabetic patients. A cohort of 108 consecutive diabetic patients without angina pectoris or known CAD, undergoing CCTA was included. 1379 consecutive patients without diabetes were defined as a control group. Coronary artery calcium score (CACS), segment involvement score (SIS) and the segment stenosis score (SSS) were documented. The end point was a composite of cardiac events defined as all-cause death, nonfatal myocardial infarction, or unstable angina requiring hos...
Source: The International Journal of Cardiovascular Imaging - October 10, 2015 Category: Radiology Source Type: research

An elderly patient with non-corrected interruption of the aortic arch in need of total hip replacement: role of preoperative imaging
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 9, 2015 Category: Radiology Source Type: research

The significance of aortic valve calcification in patients with bicuspid aortic valve disease
Abstract Bicuspid aortic valve (BAV) is a common congenital heart disease. Our study was to analyze clinical features of BAV and evaluate whether aortic valve calcium score (AVCS) was a reliable marker for aortic stenosis (AS) in patients with BAV. 101 patients with BAV who both underwent echocardiology and cardiac computed tomography (CT) scan in our institution were included. Basic clinical data, haemodynamic feature, aortic valve and coronary calcium score were collected and compared among patients with different valve function and different degree of AS. Risk factors related to severe AS were evaluated by logi...
Source: The International Journal of Cardiovascular Imaging - October 6, 2015 Category: Radiology Source Type: research

Validity of the size-specific dose estimate in adults undergoing coronary CT angiography: comparison with the volume CT dose index
Abstract Size-specific dose estimate (SSDE) takes into account the patient size but remains to be fully validated for adult coronary computed tomography angiography (CCTA). We investigated the appropriateness of SSDE for accurate estimation of patient dose by comparing the SSDE and the volume CT dose index (CTDIvol) in adult CCTA. This prospective study received institutional review board approval, and informed consent was obtained from each patient. We enrolled 37 adults who underwent CCTA with a 320-row CT. High-sensitivity metal oxide semiconductor field effect transistor dosimeters were placed on the anterior ...
Source: The International Journal of Cardiovascular Imaging - October 6, 2015 Category: Radiology Source Type: research

Topical issue: multimodality imaging in atherosclerosis
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 5, 2015 Category: Radiology Source Type: research

Bioimpedance analysis versus lung ultrasonography for optimal risk prediction in hemodialysis patients
Abstract Fluid overload is associated with adverse outcomes in hemodialysis (HD) patients. Two bedside methods are increasingly utilized to evaluate objectively fluid status—bioimpedance and lung ultrasonography, but there is no available direct, head-to-head comparison of their prognostic significance. Importantly, their predictive abilities have never been tested in a HD population, alongside those of a classic model that also incorporates established echocardiographic parameters of increased mortality risk. Between 26 May 2011 and 26 October 2012, we included in the study 173 patients undergoing chron...
Source: The International Journal of Cardiovascular Imaging - October 1, 2015 Category: Radiology Source Type: research

Relationship between left ventricular mass and coronary artery disease in young adults: a single-center study using cardiac computed tomography
Abstract We evaluated the relationship between coronary artery disease (CAD) and left ventricular mass (LVM) as measured by cardiac computed tomography (CT) in young adults ≤40 years of age. We retrospectively enrolled 490 consecutive individuals (383 males; mean age, 35.2 ± 4.4 years) who underwent cardiac CT. CAD was defined by the presence of any plaque detected by coronary CT angiography. Left ventricular (LV) function, including LVM, was automatically measured by a dedicated workstation. LVM and LVM index (LVMi) in patients with CT-detected CAD were compared to those of patie...
Source: The International Journal of Cardiovascular Imaging - October 1, 2015 Category: Radiology Source Type: research

Regional right ventricular dysfunction in acute pulmonary embolism: relationship with clot burden and biomarker profile
This study investigated the clinical importance of RRVD by assessing its relationship with clot burden and biomarkers. We identified consecutive patients admitted to the emergency department between 1999 and 2014 who underwent computed tomographic angiography, echocardiography, and biomarker testing (troponin and NT-proBNP) for suspected acute PE. RRVD was defined as normal excursion of the apex contrasting with hypokinesis of the mid-free wall segment. RV assessment included measurements of ventricular dimensions, fractional area change, free-wall longitudinal strain and tricuspid annular plane systolic excursion. Clot bu...
Source: The International Journal of Cardiovascular Imaging - October 1, 2015 Category: Radiology Source Type: research

Carotid thin fluttering bands: A new element of arterial wall remodelling? An ultrasound study
Abstract Carotid artery ultrasound is a non-invasive and reproducible technique used for early atherosclerotic assessment. Intimal flap has been described in the presence of dissection or mobile plaque rupture, however presence of carotid thin fluttering bands (TFBs) have not been described yet. To investigate frequency, characteristics and impact of TFBs in carotid lumen of patients who underwent carotid ultrasound scan (CUS). 3341 patients were admitted from January 2009 to January 2014. Patients with history of cerebral ischemia (CI) were excluded. In the cases in which TFBs were observed, a 3-months clinical ...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Presence and extent of coronary calcified plaque evaluated by coronary computed tomographic angiography are independent predictors of ischemic stroke in patients with suspected coronary artery disease
Abstract Although ischemic stroke and coronary artery disease (CAD) share common risk factors and pathophysiology, the risk of stroke in patients with CAD remains unclear. We sought to evaluate the risk of ischemic stroke in patients with suspected CAD according to coronary computed tomographic angiography (CCTA) and single-photon emission computed tomography (SPECT) findings. Presence, severity, and extent of CAD were evaluated in 1137 patients with suspected CAD who underwent CCTA and SPECT. Primary outcome was the occurrence of ischemic stroke. During follow-up (median 26 months), ischemic stroke was ...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Prediction of paravalvular leakage after transcatheter aortic valve implantation
Abstract Significant paravalvular leakage (PVL) after transcatheter aortic valve implantation (TAVI) is related to patient mortality. Predicting the development of PVL has focused on computed tomography (CT) derived variables but literature targeting CoreValve devices is limited, controversial, and did not make use of standardized echocardiographic methods. The study included 164 consecutive patients with severe aortic stenosis that underwent TAVI with a Medtronic CoreValve system©, with available pre-TAVI CT and pre-discharge transthoracic echocardiography. The predictive value for significant PVL of the CT...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Dynamic CT perfusion measurement in a cardiac phantom
In conclusion, the results of the study indicate that the FPA technique can make accurate dynamic CT perfusion measurements over a range of clinically relevant perfusion rates, while substantially reducing radiation dose, as compared to currently available dynamic CT perfusion techniques. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Diastolic myocardial dysfunction by tissue Doppler imaging predicts mortality in patients with cerebral infarction
Abstract Several clinical prediction score models have been investigated for predicting mortality in patients with cerebral infarction. However, none of these include echocardiographic measures. Our objective was to evaluate the prognostic value of tissue Doppler imaging (TDI) of the myocardium in patients with cerebral infarction. Two hundred forty-four patients with cerebral infarction and subsequent echocardiographic examination in sinus rhythm were identified. Using TDI in three apical projections, longitudinal mitral annular velocities were obtained in six segments. Cox regression models, C-statistics and re...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Automatic quantification of aortic regurgitation using 3D full volume color doppler echocardiography: a validation study with cardiac magnetic resonance imaging
Abstract Recent advances in real-time three-dimensional (3D) echocardiography provide the automated measurement of mitral inflow and aortic stroke volume without the need to assume the geometry of the heart. The aim of this study is to explore the ability of 3D full volume color Doppler echocardiography (FVCDE) to quantify aortic regurgitation (AR). Thirty-two patients with more than a moderate degree of AR were enrolled. AR volume was measured by (1) two-dimensional-CDE, using the proximal isovelocity surface area (PISA) and (2) real-time 3D-FVCDE with (3) phase-contrast cardiac magnetic resonance imaging (PC-CM...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Defining the real-world reproducibility of visual grading of left ventricular function and visual estimation of left ventricular ejection fraction: impact of image quality, experience and accreditation
Abstract Left ventricular function can be evaluated by qualitative grading and by eyeball estimation of ejection fraction (EF). We sought to define the reproducibility of these techniques, and how they are affected by image quality, experience and accreditation. Twenty apical four-chamber echocardiographic cine loops (Online Resource 1–20) of varying image quality and left ventricular function were anonymized and presented to 35 operators. Operators were asked to provide (1) a one-phrase grading of global systolic function (2) an “eyeball” EF estimate and (3) an image quality rating on...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Impact of monitoring longitudinal systolic strain changes during serial echocardiography on outcome in patients with AL amyloidosis
Abstract Relative apical sparing of longitudinal systolic strain (LSsys) with preserved LSsys at apical and significantly reduced LSsys at mid/basal segments is a typical echocardiographic feature in AL amyloidosis patients with cardiac involvement. The present study aims to evaluate the change of this typical feature over time by serial echocardiography and its impact on outcome in AL amyloidosis patients with cardiac involvement. Echocardiography was performed in 24 consecutive patients with biopsy-proven AL amyloidosis (mean age 64 ± 9 years; 50 % male) at baseline and during a media...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Echocardiography in the diagnosis of patients with absent pulmonary valve syndrome: a review study of 12 years
Abstract Absent pulmonary valve syndrome (APVS) is a rare congenital heart disease that is easily misdiagnosed as tetralogy of Fallot (TOF). We herein discuss the echocardiographic features of APVS, compare its two subtypes, and clarify some differences between APVS and TOF. From July 1998 to October 2011, 31 patients diagnosed with APVS at Fuwai Hospital underwent echocardiography, computed tomography, or cardiac angiography. APVS was clinically categorized as either infant-type or child-type. We compared the echocardiographic similarities and differences between APVS and TOF and between the two subtypes of ...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaques
Abstract Non-invasive detection of specific atherosclerotic plaque components related to vulnerability is of high clinical relevance to prevent cerebrovascular events. The feasibility of magnetic resonance imaging (MRI) for characterization of plaque components was already demonstrated. We aimed to evaluate the potential of ex vivo differential phase contrast X-ray tomography (DPC) to accurately characterize human carotid plaque components in comparison to high field multicontrast MRI and histopathology. Two human plaque segments, obtained from carotid endarterectomy, classified according to criteria of the Ameri...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Influence of plaque characteristics on fractional flow reserve for coronary lesions with intermediate to obstructive stenosis: insights from integrated-backscatter intravascular ultrasound analysis
Abstract The aim of this study was to determine the correlation between the fractional flow reserve (FFR) values and volumetric intravascular ultrasound (IVUS) parameters derived from classic gray-scale IVUS and integrated backscatter (IB)-IVUS, taking into account known confounding factors. Patients with unstable angina pectoris with the frequent development of vulnerable plaques often showed the discrepancy between the FFR value and the quantitative coronary angiography findings. Our target population was 107 consecutive subjects with 114 isolated lesions who were scheduled for elective coronary angiography. Th...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Mitral paravalvular leak generating a Coanda effect inside the left atrium appendage
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Retrograde guidewire fracture complicated with pericardial tamponade in chronic total occlusive coronary lesion
We report a case of successful surgical removal of fractured and entrapped guidewire in a septal channel during retrograde CTO intervention in a patient complicated with pericardial tamponade by delayed penetration of broken guidewire into pericardium. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Computed tomography segmental calcium score (SCS) to predict stenosis severity of calcified coronary lesions
Abstract To estimate the probability of ≥50 % coronary stenoses based on computed tomography (CT) segmental calcium score (SCS) and clinical factors. The Institutional Review Board approved the study. A training sample of 201 patients underwent CT calcium scoring and conventional coronary angiography (CCA). All patients consented to undergo CT before CCA after being informed of the additional radiation dose. SCS and calcification morphology were assessed in individual coronary segments. We explored the predictive value of patient’s symptoms, clinical history, SCS and calcification morphology. We deve...
Source: The International Journal of Cardiovascular Imaging - September 14, 2015 Category: Radiology Source Type: research

Isolated hypoplasia of the left ventricular apex
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 8, 2015 Category: Radiology Source Type: research

Cardiac CT angiography for evaluation of acute chest pain
Abstract Chest pain is the second most common emergency department (ED) presentation in the United States. Cardiac computed tomography angiography (CCTA) now plays an important role in the evaluation of patients with suspected acute coronary syndrome in the ED setting. In this article, we review the available techniques focused on the use of CCTA to evaluate patients fosr coronary atherosclerosis for timely triage of acute chest pain. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 5, 2015 Category: Radiology Source Type: research

Radiologic evaluation of coronary artery disease in adults with congenital heart disease
Abstract Improved surgical and medical therapy have prolonged survival in patients with congenital heart disease (CHD) such that general medical conditions like coronary artery disease (CAD) are now the main determinants of mortality. A summary of the association of CAD with CHD, as well as a discussion of the radiologic evaluation of the coronary arteries in adults with CHD is described herein. Cross sectional imaging to evaluate CAD in adults with CHD should follow the same appropriateness criteria as gender and aged matched patients without CHD. Coronary CT imaging may be particularly valuable in evaluating the...
Source: The International Journal of Cardiovascular Imaging - September 5, 2015 Category: Radiology Source Type: research

An unusual cause of cardioembolic stroke
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 4, 2015 Category: Radiology Source Type: research

Relationship between epicardial fat and quantitative coronary artery plaque progression: insights from computer tomography coronary angiography
Abstract Epicardial fat volume (EFV) has been suggested to promote atherosclerotic plaque development in coronary arteries, and has been correlated with both coronary stenosis and acute coronary events. Although associated with progression of coronary calcification burden, a relationship with progression of coronary atheroma volume has not been previously tested. We studied patients who had clinically indicated serial 320-row multi-detector computer tomography coronary angiography with a median 25-month interval. EFV was measured at baseline and follow-up. In vessels with coronary stenosis, quantitative analysis w...
Source: The International Journal of Cardiovascular Imaging - September 3, 2015 Category: Radiology Source Type: research

Costs and clinical outcomes for non-invasive versus invasive diagnostic approaches to patients with suspected in-stent restenosis
This study compared costs and clinical outcomes of invasive versus non-invasive diagnostic evaluations for patients with suspected in-stent restenosis (ISR) after percutaneous coronary intervention. We developed a decision model to compare 2 year diagnosis-related costs for patients who presented with suspected ISR and were evaluated by: (1) invasive coronary angiography (ICA); (2) non-invasive stress testing strategy of myocardial perfusion imaging (MPI) with referral to ICA based on MPI; (3) coronary CT angiography-based testing strategy with referral to ICA based on CCTA. Costs were modeled from the payer’s p...
Source: The International Journal of Cardiovascular Imaging - September 3, 2015 Category: Radiology Source Type: research

Diagnosing coronary artery disease by sound analysis from coronary stenosis induced turbulent blood flow: diagnostic performance in patients with stable angina pectoris
Abstract Optimizing risk assessment may reduce use of advanced diagnostic testing in patients with symptoms suggestive of stable coronary artery disease (CAD). Detection of diastolic murmurs from post-stenotic coronary turbulence with an acoustic sensor placed on the chest wall can serve as an easy, safe, and low-cost supplement to assist in the diagnosis of CAD. The aim of this study was to evaluate the diagnostic accuracy of an acoustic test (CAD-score) to detect CAD and compare it to clinical risk stratification and coronary artery calcium score (CACS). We prospectively enrolled patients with symptoms of CAD re...
Source: The International Journal of Cardiovascular Imaging - September 3, 2015 Category: Radiology Source Type: research

Defining the optimal systolic phase targets using absolute delay time for reconstructions in dual-source coronary CT angiography
Abstract To define the optimal systolic phase for dual-source computed tomography angiography using an absolute reconstruction delay time after the R–R interval based on the coronary artery motion, we analyzed images reconstructed between 200 and 420 miliseconds (ms) after the R wave at 20 ms increments in 21 patients. Based on the American Heart Association coronary segmentation guidelines, the origin of six coronary artery landmarks (RCA, AM1, PDA, LM, OM1, and D2) were selected to calculate the coronary artery motion velocity. The velocity of the given landmark was defined as the quotient of the rout...
Source: The International Journal of Cardiovascular Imaging - September 3, 2015 Category: Radiology Source Type: research

Different responses of the myocardial contractility by layer following acute pressure unloading in severe aortic stenosis patients
Abstract The present study evaluated change in left ventricle (LV) biomechanics, layer-by-layer, following acute pressure unloading in patients with severe aortic stenosis (AS). In twenty-eight consecutive patients with severe AS who underwent transcatheter aortic valve replacement (TAVR), LV peak global longitudinal and circumferential strains of the endo-, midmyo- and epicardium were evaluated using multilayer speckle tracking echocardiography before, 1 week after, and 1 month after TAVR. Longitudinal and circumferential strains were significantly highest in the endocardium and lowest in the epicardium...
Source: The International Journal of Cardiovascular Imaging - September 1, 2015 Category: Radiology Source Type: research

Bioresorbable vascular scaffold overlap evaluation with optical coherence tomography after implantation with or without enhanced stent visualization system (WOLFIE study): a two-centre prospective comparison
Abstract To assess if enhanced stent visualization (ESV)-guided implantation of overlapping bioresorbable vascular scaffold (BVS) is superior to angiography alone-guided implantation in the reduction of overlap length. WOLFIE is a two-centre prospective open study enrolling 30 patients treated with implantation of at least two overlapping BVS. In the first centre (London), BVS implantation was guided by conventional angiography, while in the second centre (Ferrara), an ESV system was systematically employed. The primary endpoint of the study was overlap length. Secondary endpoints were: stacked struts number, area...
Source: The International Journal of Cardiovascular Imaging - August 31, 2015 Category: Radiology Source Type: research

Diagnostic performance of quantitative coronary computed tomography angiography and quantitative coronary angiography to predict hemodynamic significance of intermediate-grade stenoses
Abstract Fractional flow reserve (FFR) during invasive coronary angiography has become an established tool for guiding treatment. However, only one-third of intermediate-grade coronary artery stenosis (ICAS) are hemodynamically significant and require coronary revascularization. Additionally, the severity of stenosis visually established by coronary computed tomography angiography (CCTA) does not reliably correlate with the functional severity. Therefore, additional angiographic morphologic descriptors affecting hemodynamic significance are required. To evaluate quantitative stenosis analysis and plaque descriptor...
Source: The International Journal of Cardiovascular Imaging - August 31, 2015 Category: Radiology Source Type: research

Semiautomatic three-dimensional CT ventricular volumetry in patients with congenital heart disease: agreement between two methods with different user interaction
Abstract To assess agreement between two semi-automatic, three-dimensional (3D) computed tomography (CT) ventricular volumetry methods with different user interactions in patients with congenital heart disease. In 30 patients with congenital heart disease (median age 8 years, range 5 days–33 years; 20 men), dual-source, multi-section, electrocardiography-synchronized cardiac CT was obtained at the end-systolic (n = 22) and/or end-diastolic (n = 28) phase. Nineteen left ventricle end-systolic (LV ESV), 28 left ventricle end-diastolic (LV EDV), 22 right ventricle end-systolic...
Source: The International Journal of Cardiovascular Imaging - August 29, 2015 Category: Radiology Source Type: research

The impact of gender on cardiovascular system calcification in very elderly patients with severe aortic stenosis
This study demonstrates a significant sex impact on calcification in the coronary beds and aortic valve in elderly patients with severe AS. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - August 29, 2015 Category: Radiology Source Type: research

Effect of statins on aortic root growth rate in patients with bicuspid aortic valve anatomy
In conclusion, in patients with BAV, although the use of statins was associated with smaller ascending aorta, the annual dilation rate of the aortic root was not influenced by the use of statins. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - August 28, 2015 Category: Radiology Source Type: research

Independent association between brachial-ankle pulse wave velocity and global longitudinal strain of left ventricle
This study was performed to investigate the association between brachial-ankle pulse wave velocity (baPWV) and LV global longitudinal strain (GLS). A total of 248 subjects (mean age 59.2 ± 12.3 years; 50 % were men) without structural heart problems were retrospectively evaluated. LV GLS was measured by 2-dimensional speckle-tracking echocardiography. baPWV measurements were made on the same day of echocardiography. The incidences of hypertension, diabetes mellitus, and dyslipidemia were 51.2, 19.4, and 22.2 %, respectively. The mean value of baPWV was 1557 ± 285 cm/s. ...
Source: The International Journal of Cardiovascular Imaging - August 23, 2015 Category: Radiology Source Type: research

Intra-individual comparison of carotid and femoral atherosclerotic plaque features with in vivo MR plaque imaging
Abstract The purpose of this study was to evaluate differences of plaque composition and morphology within the same patient in different vascular beds using non-invasive MR-plaque imaging. 28 patients (67.8 ± 7.4 years, 8 females) with high Framingham general cardiovascular disease 10-year risk score and mild-to-moderate atherosclerosis were consecutively included in the study. All subjects underwent a dedicated MRI-plaque imaging protocol using TOF and T1w and T2w black-blood-sequences with fat suppression at 1.5 T. The scan was centered on the carotid bulb of the carotid arteries and o...
Source: The International Journal of Cardiovascular Imaging - August 22, 2015 Category: Radiology Source Type: research