Feasibility of measurements of valve dimensions in en-face-3D transesophageal echocardiography
AbstractNewest 3D software allows measurements directly in the en-face-3D TEE mode. Aim of the study was to ascertain whether measurements performed in the en-face-3D TEE mode are comparable with conventional measurement methods based on 2D TEE and 3D using the multiple plane reconstruction mode with the Qlab® software. En-face-3D TEE is used more frequently in daily clinical routine during cardiac operations. So far measurements could only be done based on 2D images or with the use of multi planar reconstruction mode with additional software. Measurement directly in the 3D image (en-face-3D TEE) would make measurement...
Source: The International Journal of Cardiovascular Imaging - October 1, 2017 Category: Radiology Source Type: research

Evaluation of left ventricular myocardial mechanics by three-dimensional speckle tracking echocardiography in the patients with different graded coronary artery stenosis
AbstractTo investigate the relationship between left ventricular (LV) myocardial mechanics evaluated by three-dimensional speckle tracking echocardiography (3D-STE) and degree of coronary artery stenosis in patients with coronary artery disease (CAD). Ninety-seven suspected CAD patients without LV regional wall motion abnormality (RWMA) observed visually form traditional echocardiography were divided into four groups according to coronary artery angiography (CAG): 23 patients in slight stenosis group [stenosis rate (SR)  ≤25%], 26 patients in mild stenosis group (2550%, and 0.896, 0.866, 0.797, 0.909 and 0.899 re...
Source: The International Journal of Cardiovascular Imaging - October 1, 2017 Category: Radiology Source Type: research

Two cases of quadricuspid aortic valve diagnosed via coronary CT angiogram
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 1, 2017 Category: Radiology Source Type: research

Erratum to: Ventricular pacing site separation by cardiac computed tomography: validation for the prediction of clinical response to cardiac resynchronization therapy
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - October 1, 2017 Category: Radiology Source Type: research

Comparative assessment of three drug eluting stents with different platforms but with the same biodegradable polymer and the drug based on quantitative coronary angiography and optical coherence tomography at 12-month follow-up
AbstractThe aim of this study was to compare neointima proliferation in three drug-eluting stents (DES) produced by the same company (Balton, Poland) which are covered with a biodegradable polymer and elute sirolimus (concentration: 1.0 and 1.2  µg/mm2), but have different stent platforms and strut thickness: stainless steel Prolim® (115  µm) and BiOSS LIM® (120  µm) and cobalt-chromium Alex® (70  µm). We analyzed data of patients with quantitative coronary angiography (QCA) and optical coherence tomography (OCT) at 12 months from BiOSS LIM Registry, Prolim Registry a...
Source: The International Journal of Cardiovascular Imaging - September 30, 2017 Category: Radiology Source Type: research

Biventricular vortex ring formation corresponds to regions of highest intraventricular viscous energy loss in a Fontan patient: analysis by 4D Flow MRI
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 30, 2017 Category: Radiology Source Type: research

Magnetic resonance guided renal denervation using active tracking: first in vivo experience in Swine
The objective of the present study was to prove feasibility and estimate safety of renal sympathetic denervation guided by real-time iCMR using active tracking. Six pigs were examined in a 1.5  T MRI-System (Achieva, Philips Healthcare, Best, Netherlands) equipped with non-invasive hemodynamic control and in-room monitors displaying an interventional software platform [Interventional MRI Suite (iSuite), Philips Research, Hamburg, Germany]. MR-guided renal denervation was performed using a MR conditional non-irrigated ablation catheter with active tracking (Imricor, Burnsville, MN, USA). Real-time imaging for device gu...
Source: The International Journal of Cardiovascular Imaging - September 27, 2017 Category: Radiology Source Type: research

Intravascular ultrasound assessment of the effect of laser energy on the arterial wall during the treatment of femoro-popliteal lesions: a CliRpath excimer laser system to enlarge lumen openings (CELLO) registry study
AbstractThe CliRpath Excimer Laser System to Enlarge Lumen Openings (CELLO) registry included patients treated with modified excimer laser catheters for the endovascular treatment of peripheral artery disease affecting the superficial femoral artery (SFA) and proximal popliteal artery. The aim of this study was to assess, via intravascular ultrasound (IVUS) the dissections in the vessel wall following treatment with the laser catheters. IVUS grayscale images from the CELLO registry were systematically reviewed for dissections in the treated vessel segments by two investigators. Images from 33 patients; 66 pullbacks (1867 I...
Source: The International Journal of Cardiovascular Imaging - September 26, 2017 Category: Radiology Source Type: research

Improvement of continuous subcutaneous insulin infusion on patients with type 2 diabetes mellitus by 3-dimensional speckle tracking echocardiography
AbstractThree-dimensional speckle tracking echocardiography (3D-STE) was used to evaluate the improvement of continuous subcutaneous insulin infusion on the left ventricular (LV) systolic function of patients with type 2 diabetes mellitu (T2DM). We recruited T2DM patients (38 cases, diabetic group) and healthy volunteers (35 cases, control group) to collect LV full volume imaging. TomTec software was used for calculating LV global longitudinal strain (LVGLS), global circumferential strain (LVGCS), peak twist (LVTW), peak apical rotation (LVPAR), ejection fraction (LVEF), and torsion (LVT). All indices were re-tested 2 &nbs...
Source: The International Journal of Cardiovascular Imaging - September 21, 2017 Category: Radiology Source Type: research

Serial assessment of left ventricular morphology and function in a rodent model of ischemic cardiomyopathy
AbstractLeft ventricular remodelling (LVr) occurs post myocardial infarction (MI), predisposing people to heart failure (HF). LV mechanics and morphology are important in this process. We hence sort to characterize LV mechanics and geometry in a post-MI rodent model. Thirty-two male Sprague –Dawley rats (150–200 g) sustained MI (n = 24) or sham (Sham; n = 8) surgery. In another six sham rats invasive blood pressure measurements were performed. Ultrasound imaging was done at baseline, and 1, 3, 7, 14, 30 and 60 days following surgery, and LV mechanics and morphology assess e...
Source: The International Journal of Cardiovascular Imaging - September 19, 2017 Category: Radiology Source Type: research

Honeycomb-like appearance on optical coherence tomography in right coronary artery
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 18, 2017 Category: Radiology Source Type: research

Left atrial volume computed by 3D rotational angiography best predicts atrial fibrillation recurrence after circumferential pulmonary vein isolation
AbstractLeft atrium (LA) size is a well-studied predictor of atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). Yet, there is still little agreement on the best imaging technique to size the LA, and on the most appropriate sizing parameter. Volumetric assessment of LA with three-dimensional rotational angiography (3DRA LA volume index) might be a valid alternative to the commonly used transthoracic echocardiography (TTE LA volume index). The aim of our study was to investigate whether LA volume by 3DRA at the time of PVI is able to predict the risk of atrial fibrillation recurrence. We analysed 352 c...
Source: The International Journal of Cardiovascular Imaging - September 16, 2017 Category: Radiology Source Type: research

Unorthodox right parasternal imaging saves the day
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 16, 2017 Category: Radiology Source Type: research

Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast
AbstractBoth noncontrast and contrast-enhanced approaches to gated thoracic magnetic resonance angiography (MRA) for aortic root evaluation have been reported at 3T. We compare qualitative and quantitative image quality measures for the two approaches, and assess the reproducibility of standard aortic measurements. Respiratory and cardiac gated MRA of the chest was performed at 3T in 45 patients: 23 after administration of iron-based blood pool contrast, and 22 without contrast. Image quality was assessed with a 5-point Likert scale, vessel lumen-to-muscle contrast ratios, and vessel wall sharpness. Two reviewers measured ...
Source: The International Journal of Cardiovascular Imaging - September 13, 2017 Category: Radiology Source Type: research

Submillisievert imaging protocol using full reconstruction and advanced patient motion correction in 320-row area detector coronary CT angiography
AbstractRadiation exposure remains a concern in the use of coronary CT angiography (CCTA). Full reconstruction (Full) and reconstruction using advanced patient motion correction (APMC) could obtain a lower radiation dose using low tube current scanning in a 320-row Area Detector CT (320-ADCT). The radiation dose for an imaging protocol using Full and APMC in daily practice was estimated. A total of 209 patients who underwent CCTA in 1 rotation scanning with 100 kv and adaptive iterative dose reduction 3D in 320-ADCT were enrolled. Imaging protocols were classified into 3 groups based on estimated slow filling time: (1) slo...
Source: The International Journal of Cardiovascular Imaging - September 12, 2017 Category: Radiology Source Type: research

Myocardial contractile patterns predict future cardiac events in sarcoidosis
AbstractThe poor prognosis of cardiac sarcoidosis (CS) underscores the need for risk stratification. We evaluated 84 consecutive sarcoidosis patients who were referred for echocardiographic studies for cardiac symptoms or abnormal electrocardiograms. In 54 patients without previous diagnosis of CS or other known structural heart disease, 13 reached endpoints during (median) 24 months follow up. Significantly impaired peak systolic longitudinal strain in their original echocardiograms were identified in 13 of 17 left ventricular segments, clustering in the free wall, interventricular septum and apex. The regional (including...
Source: The International Journal of Cardiovascular Imaging - September 9, 2017 Category: Radiology Source Type: research

Predictive value of SYNTAX score II for clinical outcomes in cardiogenic shock underwent primary percutaneous coronary intervention; a pilot study
AbstractSYNTAX Score II (SSII) connects clinical variables with coronary anatomy. We investigated the prognostic value of SSII in patients with ST segment elevated myocardial infarction (STEMI) complicated with cardiogenic shock treated with primary percutaneous coronary intervention (PPCI). In this retrospective analysis, we evaluated the in-hospital prognostic impact of SSII on 492 patients with STEMI complicated with cardiogenic shock treated with PPCI. Patients were stratified by tertiles of SSII, in-hospital clinical outcomes were compared between those groups. In-hospital univariate analysis revealed higher rates of ...
Source: The International Journal of Cardiovascular Imaging - September 9, 2017 Category: Radiology Source Type: research

4D flow image quality with blood pool contrast: a comparison of gadofosveset trisodium and ferumoxytol
AbstractTo evaluate the effect of MRI blood pool contrast agent on 4D flow image quality and ventricular volume measurements. Adult patients referred for clinical cardiac MRI (n  = 22) were imaged with 4D flow. Patients with renal failure (n = 10) received ferumoxytol, and the remainder (n = 12) received gadofosveset trisodium. Image quality was assessed with (1) signal-to-noise ratio (SNR); (2) contrast-to-noise ratio (CNR); and (3) 5-point Likert scale based o n endocardial border definition (1 = none; 2 = partial but unable to visualize; 3 =&th...
Source: The International Journal of Cardiovascular Imaging - September 8, 2017 Category: Radiology Source Type: research

Characterization of complex flow patterns in the ascending aorta in patients with aortic regurgitation using conventional phase-contrast velocity MRI
In conclusion, conventional PC-FRC data can detect and quantify FD in patients wi th AR suggesting the curves as a research and screening tool in larger patient populations. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - September 4, 2017 Category: Radiology Source Type: research

4D modelling for rapid assessment of biventricular function in congenital heart disease
AbstractAlthough more patients with congenital heart disease (CHD) are now living longer due to better surgical interventions, they require regular imaging to monitor cardiac performance. There is a need for robust clinical tools which can accurately assess cardiac function of both the left and right ventricles in these patients. We have developed methods to rapidly quantify 4D (3D + time) biventricular function from standard cardiac MRI examinations. A finite element model was interactively customized to patient images using guide-point modelling. Computational efficiency and ability to model large deformations was improv...
Source: The International Journal of Cardiovascular Imaging - August 30, 2017 Category: Radiology Source Type: research

Myocardial T1 mapping and extracellular volume quantification: an overview of technical and biological confounders
This article is intended as an overview of the physical and physiological mechanisms un derlying the interpretation and the accuracy of any practical measurement of T1, or derived biomarkers such as extravascular volume fraction, and also includes a discussion of potential pitfalls. Numerous caveats und knowledge gaps related to the precise interpretation of T1-based biomarkers remain, which are being addressed incrementally through ongoing research. Equally important, further careful standardization will pave the way for a wider clinical translation of these novel T1-based biomarkers of tissue remodeling, which have ...
Source: The International Journal of Cardiovascular Imaging - August 28, 2017 Category: Radiology Source Type: research

Comprehensive echocardiographic assessment of biventricular function in the rabbit, animal model in cardiovascular research: feasibility and normal values
AbstractQuantification of cardiac structure and function is central in cardiovascular research. Rabbits are valuable research models of cardiovascular human disease; however, there is little normal data available. The aim of this study was to investigate feasibility and provide normal values for comprehensive echocardiographic assessment of biventricular function in rabbits. New Zealand white rabbits underwent trans-thoracic echocardiography using a general electric (GE) Vivid 7/E9 system with a 10  MHz transducer, under light sedation, to evaluate biventricular function and dimensions. Images for two-dimensional, M-m...
Source: The International Journal of Cardiovascular Imaging - August 24, 2017 Category: Radiology Source Type: research

Fully-automated left ventricular mass and volume MRI analysis in the UK Biobank population cohort: evaluation of initial results
AbstractUK Biobank, a large cohort study, plans to acquire 100,000 cardiac MRI studies by 2020. Although fully-automated left ventricular (LV) analysis was performed in the original acquisition, this was not designed for unsupervised incorporation into epidemiological studies. We sought to evaluate automated LV mass and volume (Siemenssyngo InlineVF versions D13A and E11C), against manual analysis in a substantial sub-cohort of UK Biobank participants. Eight readers from two centers, trained to give consistent results, manually analyzed 4874 UK Biobank cases for LV end-diastolic volume (EDV), end-systolic volume (ESV), str...
Source: The International Journal of Cardiovascular Imaging - August 23, 2017 Category: Radiology Source Type: research

Longitudinal two-dimensional strain for the diagnosis of left ventricular segmental dysfunction in patients with acute myocardial infarction
The objectives of this study were  to assess whether 2-dimensional strain (2DS) can detect left ventricular (LV) segmental dysfunction and to compare the diagnostic accuracy of various 2DS parameters. Multiple segmental longitudinal 2DS parameters were measured in 54 patients with a first myocardial infarction and single vessel cor onary artery disease (age: 56 ± 11 years, 74% men, LV ejection fraction: 47 ± 10%, left anterior descending artery occlusion in 63%) and 14 age-matched subjects. 2DS parameters were compared to visual assessment of segmental function by multiple obs...
Source: The International Journal of Cardiovascular Imaging - August 20, 2017 Category: Radiology Source Type: research

Cardiac death in patients with left ventricular aneurysm, remodeling and myocardial viability by gated 99m Tc-MIBI SPECT and gated 18 F-FDG PET
Abstract(1) To evaluate the prognostic value of LV remodeling parameters in patients with LV aneurysm by gated SPECT (GSPECT), gated PET (GPET) and CMR; (2) to evaluate the impact of myocardial viability and LV remodeling on the long-term cardiac survival in patients with LV aneurysm. One hundred and twenty-six consecutive patients underwent GPET, GSPECT and CMR within two weeks, with a mean follow-up of 3.9  ± 1.5 years. End-diastolic volume (EDV, mL) and end-systolic volume (ESV, mL) measured by GPET, GSPECT and CMR and corrected for BSA; EDVI and ESVI were calculated. Patients were divided into thre...
Source: The International Journal of Cardiovascular Imaging - August 19, 2017 Category: Radiology Source Type: research

New echocardiographic parameters in the diagnosis of heart failure with preserved ejection fraction
AbstractHeart failure with preserved ejection fraction (HFpEF) is a serious clinical disease. The pathophysiology of HFpEF is complex, and specific diagnostic criteria have evolved over time. Limited data are available on the quantification of diastolic function using two-dimensional real-time echocardiography, and a simple parameter has not yet been established. The aim of this work is to evaluate new echocardiographic parameters —the diastolic wall strain of the posterior wall (DWS PW) and the vortex formation time (VFT). Echocardiographic data from 111 subjects with exertional dyspnea and normal left ejection frac...
Source: The International Journal of Cardiovascular Imaging - August 17, 2017 Category: Radiology Source Type: research

The association of epicardial fat volume with coronary characteristics and clinical outcome
AbstractRecent studies have demonstrated the relationship between epicardial fat volume (EFV) and coronary atherosclerosis, but their association is modest at best. Our purpose is to elucidate the association of epicardial fat with coronary characteristics and clinical outcome. We performed coronary computed tomographic angiography in 651 patients and divided them into three groups according to tertiles of EFV; low-tertile (n  = 215), 36–123 ml; middle-tertile (n = 218), 124–165 ml; high-tertile (n = 218), 166–489 ml. The prevalence of coronary calcium score (CCS)...
Source: The International Journal of Cardiovascular Imaging - August 14, 2017 Category: Radiology Source Type: research

A drug-coated balloon effectively treated in-stent restenosis due to a stent fracture
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - August 14, 2017 Category: Radiology Source Type: research

Quantitative coronary plaque analysis predicts high-risk plaque morphology on coronary computed tomography angiography: results from the ROMICAT II trial
AbstractSemi-automated software can provide quantitative assessment of atherosclerotic plaques on coronary CT angiography (CTA). The relationship between established qualitative high-risk plaque features and quantitative plaque measurements has not been studied. We analyzed the association between quantitative plaque measurements and qualitative high-risk plaque features on coronary CTA. We included 260 patients with plaque who underwent coronary CTA in the Rule Out Myocardial Infarction/Ischemia Using Computer Assisted Tomography (ROMICAT) II trial. Quantitative plaque assessment and qualitative plaque characterization we...
Source: The International Journal of Cardiovascular Imaging - August 12, 2017 Category: Radiology Source Type: research

Quantitative evaluation of longitudinal strain in layer-specific myocardium in patients with preeclampsia
AbstractPreeclampsia (PE) remains a main cause of maternal morbidity and mortality during pregnancy. Vascular spasm and ischemic damage play the primary role in the presentation of PE. The aim of this study was to assess the longitudinal strain (LS) in each of the three myocardial layers in patients with PE using the layer-specific strain. Forty-five PE women and forty-one normotensive pregnant women were included. Layer-specific LS were assessed in endocardium, mid-myocardium, and epicardium by 2-dimensional (2D) speckle-tracking echocardiography (STE). Compared to the control subjects, the LS of all the three analyzed my...
Source: The International Journal of Cardiovascular Imaging - August 3, 2017 Category: Radiology Source Type: research

Acute pulmonary edema in patients with reduced left ventricular ejection fraction is associated with concentric left ventricular geometry
AbstractAlthough acute pulmonary edema (APE) is common in patients with heart failure (HF) with preserved ejection fraction (EF), its pathogenesis in patients with HF with reduced EF (HFrEF) is not completely understood. The purpose of our study was to explore the contributions of left ventricular (LV) geometry to understand the difference between HFrEF patients with or without APE. We studied 122 consecutive acute decompensated HF patients with HFrEF ( ≤40%). APE was defined as acute-onset dyspnea and radiographic alveolar edema requiring immediate airway intervention. LV geometry was determined from a combination of t...
Source: The International Journal of Cardiovascular Imaging - August 2, 2017 Category: Radiology Source Type: research

Feasibility of a single-beat prospective ECG-gated cardiac CT for comprehensive evaluation of aortic valve disease using a 256-detector row wide-volume CT scanner: an initial experience
AbstractThe aim of our study was to investigate the feasibility of single-beat prospective electrocardiogram (ECG)-gated cardiac computed tomography (CT) using a 256-detector row wide-volume CT scanner for functional and anatomical evaluation of the aortic valve (AV) and coronary arteries in patients with AV disease. A total of 50 patients who underwent cardiac CT scan with a wide-volume 256-detector row CT scanner for the evaluation of AV and aorta were retrospectively enrolled. Cardiac CT was performed using the prospective ECG-gated acquisition mode, and AV image quality was analyzed using a four-point grading system. S...
Source: The International Journal of Cardiovascular Imaging - August 2, 2017 Category: Radiology Source Type: research

Predictors of left ventricular remodeling after ST-elevation myocardial infarction
AbstractAdverse left ventricular (LV) remodeling after acute ST-elevation myocardial infarction (STEMI) is associated with morbidity and mortality. We studied clinical, biochemical and angiographic determinants of LV end diastolic volume index (LVEDVi), end systolic volume index (LVESVi) and mass index (LVMi) as global LV remodeling parameters 4 months after STEMI, as well as end diastolic wall thickness (EDWT) and end systolic wall thickness (ESWT) of the non-infarcted myocardium, as compensatory remote LV remodeling parameters. Data was collected in 271 patients participating in the GIPS-III trial, presenting with a firs...
Source: The International Journal of Cardiovascular Imaging - August 1, 2017 Category: Radiology Source Type: research

Magnetic resonance imaging for characterizing myocardial diseases
AbstractThe National Institute of Health defined cardiomyopathy as diseases of the heart muscle. These myocardial diseases have different etiology, structure and treatment. This review highlights the key imaging features of different myocardial diseases. It provides information on myocardial structure/orientation, perfusion, function and viability in diseases related to cardiomyopathy. The standard cardiac magnetic resonance imaging (MRI) sequences can reveal insight on left ventricular (LV) mass, volumes and regional contractile function in all types of cardiomyopathy diseases. Contrast enhanced MRI sequences allow visual...
Source: The International Journal of Cardiovascular Imaging - August 1, 2017 Category: Radiology Source Type: research

Reproducibility of echocardiographic assessment of 2D-derived longitudinal strain parameters in a population-based study (the STANISLAS Cohort study)
AbstractGlobal peak systolic longitudinal strain (PLS) derived from speckle tracking echocardiography (STE) is a widely used left ventricular deformation parameter. Modern ultrasound systems with improved temporal resolution and new software now allow automated multilayer analysis; however, there is limited evidence regarding its reproducibility. We performed intra- and inter-observer analyses within a population-based cohort study using conventional quantitative strain analysis (GE Healthcare). Fifty patients (49  ± 14 years) were randomly selected among the fourth visit of the STANISLAS Cohort. Multi...
Source: The International Journal of Cardiovascular Imaging - August 1, 2017 Category: Radiology Source Type: research

Normal references of right ventricular strain values by two-dimensional strain echocardiography according to the age and gender
AbstractRight ventricular (RV) strain values by 2-dimensional strain echocardiography (STE) can be used as objective markers of RV systolic function. However, there is little data about normal reference RV strain values according to age and gender. We measured normal RV strain values by STE. RV strain values were analyzed from the digitally stored echocardiographic images from NORMAL (Normal echOcardiogRaphic diMensions and functions in KoreAn popuLation) study for the measurement of normal echocardiographic values performed in 23 Korean university hospitals. We enrolled total 1003 healthy persons in the NORMAL study. Of t...
Source: The International Journal of Cardiovascular Imaging - July 27, 2017 Category: Radiology Source Type: research

Left ventricular function in patients with hypertrophic cardiomyopathy and its relation to myocardial fibrosis and exercise tolerance
AbstractWe sought to determine the relation between myocardial extracellular volume (ECV), left ventricular (LV) diastolic function, and exercise tolerance in patients with hypertrophic cardiomyopathy (HCM). Forty five HCM patients with an ejection fraction>50% and no previous septal reduction therapy underwent imaging by CMR and transthoracic echocardiography. CMR was used to quantify LV volumes, mass, EF, LA volumes, scar burden, pre and post contrast T1 relaxation times and ECV. Echocardiography was used to measure outflow tract gradients, mitral inflow and annular velocities, circumferential strain, systolic, early ...
Source: The International Journal of Cardiovascular Imaging - July 26, 2017 Category: Radiology Source Type: research

Echocardiographic and hemodynamic assessment for predicting early clinical events in severe acute mitral regurgitation
AbstractThe diagnostic role of echocardiographic and hemodynamic assessment in acute mitral regurgitation (AMR) remains unclear. The central question of this study was to determine if echocardiographic and hemodynamic parameters can predict early clinical events in AMR. AMR was induced by percutaneously severing the mitral valve chordae tendineae in 39 Yorkshire pigs. Immediately after AMR induction, echocardiographic and hemodynamic exams were performed, and compared between those who died and those who survived within 30-days of the procedure. Echocardiographic indices of MR severity as well as the left atrial pressure s...
Source: The International Journal of Cardiovascular Imaging - July 22, 2017 Category: Radiology Source Type: research

Automatic regional analysis of myocardial native T1 values: left ventricle segmentation and AHA parcellations
This study demonstrated a practical and robust method of obtaining native T1 values of AHA segments in LV walls. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - July 21, 2017 Category: Radiology Source Type: research

Left atrium passive ejection fraction is the most sensitive index of type 2 diabetes mellitus-related cardiac changes
AbstractThe aims of this study were to use cardiovascular magnetic resonance (CMR) cine to assess left atrium (LA) and left ventricle (LV) function and structure in normotensive type 2 diabetes mellitus (T2DM) patients and to identify the most sensitive index of those T2DM-related cardiac changes. Fifty T2DM patients with normotension (25 males, age 54.7  ± 8.7 years, duration of diabetes: 7.5 ± 5.1 years) and 35 controls (16 males, age: 52.2 ± 13.2 years) were prospectively enrolled. All patients were scanned using CMR four- and two-chamber long-axis cine to a...
Source: The International Journal of Cardiovascular Imaging - July 18, 2017 Category: Radiology Source Type: research

Qualitative angiographic and quantitative myocardial perfusion assessment using fluorescent cardiac imaging during graded coronary artery bypass stenosis
This study aimed to evaluate the accuracy of fluorescent cardiac imaging (FCI) for intraoperative qualitative angiographic and quantitative myocardial perfusion assessment during graded CAB stenosis compared to coronary angiography (CA). After CAB grafting to the left anterior descending coronary artery, graded distal bypass stenoses were created in ten pigs by 25, 50, 75, and 100% flow reduction assessed by transit-time flow measurement (TTFM). Visual angiographic assessment was performed by FCI and CA during baseline and graded bypass stenoses. Altered myocardial perfusion was assessed by quantitative intraoperative fluo...
Source: The International Journal of Cardiovascular Imaging - July 15, 2017 Category: Radiology Source Type: research

The diagnostic performance of SPECT-MPI to predict functional significant coronary artery disease by fractional flow reserve derived from CCTA (FFR CT ): sub-analysis from ACCURACY and VCT001 studies
AbstractAlthough single photon emission computed tomography-myocardial perfusion image (SPECT-MPI) and fractional flow reserve (FFR) derived from coronary computed tomographic angiography (CCTA) (FFRCT) have permitted functional assessment of coronary artery disease (CAD), the concordance between these modalities has not been well described. The aim of this study is to compare SPECT-MPI and anatomical stenosis by CCTA and invasive coronary angiography to FFRCT for assessing functional significance of CAD. We identified 62 patients with suspected CAD who underwent ≥64 slice coronary CTA and SPECT-MPI within 3 months...
Source: The International Journal of Cardiovascular Imaging - July 11, 2017 Category: Radiology Source Type: research

Contribution of mitral valve leaflet length and septal wall thickness to outflow tract obstruction in patients with hypertrophic cardiomyopathy
AbstractWe sought to examine whether elongation of the mitral valve leaflets in patients with hypertrophic cardiomyopathy (HCM) is synergistic to septal wall thickness (SWT) in the development of left ventricular outflow tract obstruction (LVOTO). HCM is a common genetic cardiac disease characterized by asymmetric septal hypertrophy and predisposition towards LVOTO. It has been reported that elongation of the mitral valve leaflets may be a primary phenotypic feature and contribute to LVOTO. However, the relative contribution of this finding versus SWT has not been studied. 152 patients (76 with HCM and 76 non-diseased age,...
Source: The International Journal of Cardiovascular Imaging - July 7, 2017 Category: Radiology Source Type: research

Prolonged QTc indicates the clinical severity and poor prognosis in patients with isolated left ventricular non-compaction
This study is to investigate whether or not prolonged QTc is a good indicator for evaluating the severity of fibrosis and predicting the prognosis of LVNC, and if native T1 can be used to quantify the fibrosis. 32 LVNC patients and 14 healthy controls with matched age and sex were examined by CMR and ECG to acquire native T1, QTc interval, and ECG abnormalities. 18 LVNC patients had normal QTc and 14 LVNC patients had prolonged QTc. The mean native T1 value of the normal controls, normal QTc and prolonged QTc patients was 1096.0  ± 41.5, 1141.98 ± 45.46, and 1182.67 ±...
Source: The International Journal of Cardiovascular Imaging - July 7, 2017 Category: Radiology Source Type: research

Clinical feasibility and validation of 3D principal strain analysis from cine MRI: comparison to 2D strain by MRI and 3D speckle tracking echocardiography
This study aimed to demonstrate clinical feasibility of 3D principal strain analysis from routine 2D cine MRI with validation to strain from 2D tagged cine analysis and 3D speckle tracking echocardiography. Thirty-one patients undergoing cardiac MRI were studied. 3D strain was measured from routine, multi-planar 2D cine SSFP images using custom software designed to apply 4D deformation fields to 3D cardiac models to derive principal strain. Comparisons of strain estimates versus those by 2D tagged cine, 2D non-tagged cine (feature tracking), and 3D speckle tracking echocardiography (STE) were performed. Mean age was 51 &th...
Source: The International Journal of Cardiovascular Imaging - July 6, 2017 Category: Radiology Source Type: research

Baseline mitral regurgitation predicts outcome in patients referred for dobutamine stress echocardiography
AbstractA number of parameters recorded during dobutamine stress echocardiography (DSE) are associated with worse outcome. However, the relative importance of baseline mitral regurgitation (MR) is unknown. The aim of this study was to assess the prevalence and associated implications of functional MR with long-term mortality in a large cohort of patients referred for DSE. 6745 patients (mean age 64.9  ± 12.2 years) were studied. Demographic, baseline and peak DSE data were collected. All-cause mortality was retrospectively analyzed. DSE was successfully completed in all patients with no adverse ou...
Source: The International Journal of Cardiovascular Imaging - July 6, 2017 Category: Radiology Source Type: research

Conformability in everolimus-eluting bioresorbable scaffolds compared with metal platform coronary stents in long lesions
AbstractThe aim of this study was to determine if there are significant differences in curvature of the treated vessel after the deployment of a polymeric BRS or MPS in long lesions. The impact of long polymeric bioresorbable scaffolds (BRS) compared with metallic platform stents (MPS) on vessel curvature is unknown. This retrospective study compares 32 patients who received a single everolimus-eluting BRS with 32 patients treated with a single MPS of 28  mm. Quantitative coronary angiography (QCA) was used to evaluate curvature of the treatment and peri-treatment region before and after percutaneous coronary interven...
Source: The International Journal of Cardiovascular Imaging - July 6, 2017 Category: Radiology Source Type: research

Comparison of systemic right ventricular function in transposition of the great arteries after atrial switch and congenitally corrected transposition of the great arteries
AbstractIn patients with transposition of the great arteries corrected by interatrial baffle (TGA) and those with congenitally corrected transposition of the great arteries (ccTGA) the right ventricle (RV) is subjected to systemic pressure and fails prematurely. Previous studies have demonstrated RV dysfunction may be more pronounced in patients with TGA. The present study sought to compare patients with TGA and ccTGA using three-dimensional (3D) techniques to comprehensively analyze the shape, volume, global and regional function in the systemic RV. We compared RV size, shape, and regional and global function in 25 patien...
Source: The International Journal of Cardiovascular Imaging - July 1, 2017 Category: Radiology Source Type: research

Prognostic value of tricuspid regurgitation velocity and probability of pulmonary hypertension in patients undergoing transcatheter aortic valve implantation
AbstractPulmonary hypertension (PH) is associated with adverse clinical outcomes after transcatheter aortic valve implantation (TAVI). We sought to investigate the effects of tricuspid regurgitant velocity (TRV) and echocardiographic probability of PH on clinical outcomes of patients undergoing TAVI. A total of 148 consecutive patients undergoing TAVI were included and stratified as having “low” (TRV ≤2.8 m/s), “intermediate” (TRV 2.9–3.4 m/s), and “high” (TRV>3.4  m/s) probability of PH. Only the patients from the “high” probability group were cons...
Source: The International Journal of Cardiovascular Imaging - July 1, 2017 Category: Radiology Source Type: research

In vivo visualization of braid-like appearance in Kawasaki disease: insights from multi-modality imaging
AbstractA 42-year-old gentleman with Kawasaki disease was referred for silent cardiac ischemia at inferior myocardial region. Coronary angiography showed braid-like appearance in the right coronary artery. Several channels at the segment with braid-like appearance were visualized by multi-slice computed tomography and intravascular ultrasound. Interestingly in particular, optical coherence tomography visualized the presence of multiple micro-vessels which were not detectable on other modalities. This case further elucidates distinct morphological features of braid-like lesion which potentially influences blood supply and c...
Source: The International Journal of Cardiovascular Imaging - June 30, 2017 Category: Radiology Source Type: research