Bilateral symmetry of human carotid artery atherosclerosis: a multi-contrast weighted MR study
Abstract The systemic nature of atherosclerotic disease may entail an association in disease severity between left and right carotid arteries. However, the etiology of plaque features in high-risk lesions is presumably attributed to local risk factors. We explored the symmetry of plaque morphology and composition across a broad range of atherosclerotic disease severities. All participants underwent carotid MR imaging on a 3.0 T scanner with a bilateral four-element phased-array surface coil. Vessel boundary and plaque components [calcification, lipid-rich necrotic core (LRNC) and intraplaque hemorrhage (IPH)]...
Source: The International Journal of Cardiovascular Imaging - May 2, 2016 Category: Radiology Source Type: research

Three dimensional fusion of electromechanical mapping and magnetic resonance imaging for real-time navigation of intramyocardial cell injections in a porcine model of chronic myocardial infarction
Abstract For cardiac regenerative therapy intramyocardial catheter guided cell transplantations are targeted to the infarct border zone (IBZ) i.e. the closest region of viable myocardium in the vicinity of the infarct area. For optimal therapeutic effect this area should be accurately identified. However late gadolinium enhanced magnetic resonance imaging (LGE-MRI) is the gold standard technique to determine the infarct size and location, electromechanical mapping (EMM) is used to guide percutaneous intramyocardial injections to the IBZ. Since EMM has a low spatial resolution, we aim to develop a practical and ac...
Source: The International Journal of Cardiovascular Imaging - May 1, 2016 Category: Radiology Source Type: research

Coronary artery calcium scores and cardiovascular risk factors in 31,545 asymptomatic Korean adults
Abstract The aims of this study were to identify the distribution of coronary artery calcium score (CACS) by age group and cardiovascular (CV) risk factors and to evaluate the association between CV risk factors and CACS classification in asymptomatic adults. The study included 31,545 asymptomatic Koreans, over 20 years of age with no previous history of malignancy, proven coronary artery disease, or stroke, who underwent CACS computed tomography at the Health Promotion Center, Samsung Medical Center, between January 2005 and June 2013. Mean (±SD) age was 53.8 (±8.5) years overall, 56.1 (±8.3)...
Source: The International Journal of Cardiovascular Imaging - April 27, 2016 Category: Radiology Source Type: research

Cardiovascular magnetic resonance as a reliable alternative to cardiovascular computed tomography and transesophageal echocardiography for aortic annulus valve sizing
Abstract To assess the accuracy and reproducibly of cardiovascular magnetic resonance (CMR) in the measurement of the aortic annulus and in process of valve sizing as compared to intra-operative sizing, cardiovascular computed tomography (CCT) and transesophageal echocardiography (TEE). Retrospective study on 42 patients who underwent aortic valve replacement from September 2010 to September 2015, with available records of pre surgery annulus assessment by CMR, CCT and TEE and of peri-operative assessment. In CCT and CMR, the annular plane was considered a virtual ring formed by the lowest hinge points of the valv...
Source: The International Journal of Cardiovascular Imaging - April 27, 2016 Category: Radiology Source Type: research

Relationship between left atrial appendage emptying and left atrial function using cardiac magnetic resonance in patients with atrial fibrillation: comparison with transesophageal echocardiography
Abstract To compare cardiac magnetic resonance (CMR) quantifications of left atrium (LA) function and left atrial appendage (LAA) emptying depending on the presence of LA spontaneous echogenic contrast (LA-SEC) on transesophageal echocardiography (TEE) in patients with atrial fibrillation (AF). A total of 48 patients with AF underwent sequential CMR examination and TEE in preparation for catheter ablation. The CMR protocol included cine and velocity encoding (VENC) sequences for evaluation of both LA function and LAA emptying. The peak blood velocity of LAA just before left ventricle systole was defined as the LAA...
Source: The International Journal of Cardiovascular Imaging - April 27, 2016 Category: Radiology Source Type: research

Reproducibility and observer variability of tissue phase mapping for the quantification of regional myocardial velocities
Abstract To systematically investigate the reproducibility of global and segmental left ventricular (LV) velocities derived from tissue phase mapping (TPM). Breath held and ECG synchronized TPM data (spatial/temporal resolution = 2 × 2 mm2/20.8 ms) were acquired in 18 healthy volunteers. To analyze scan–rescan variability, TPM was repeated in all subjects during a second visit separated by 16 ± 5 days. Data analysis included LV segmentation, and quantification of global and regional (AHA 16-segment modal) metrics of LV function [velocity–...
Source: The International Journal of Cardiovascular Imaging - April 26, 2016 Category: Radiology Source Type: research

Periprocedural 3D imaging of the left atrium and esophagus: comparison of different protocols of 3D rotational angiography of the left atrium and esophagus in group of 547 consecutive patients undergoing catheter ablation of the complex atrial arrhythmias
Abstract A new method in creating 3D models of the left atrium (LA) and esophagus before catheter ablation of atrial arrhythmias is 3D rotational angiography (3DRA) of the LA. The purpose of this retrospective study was to test various acquisition protocols of the 3DRA and attempt to define the parameters influencing the success of the protocols. From August 2010 to November 2014, 3DRA of the LA using the Philips Allura FD 10 X-ray system was performed in 547 consecutive patients using right atrial and left atrial protocols. Visualization of the esophagus was performed after oral administration of a contrast agent...
Source: The International Journal of Cardiovascular Imaging - April 26, 2016 Category: Radiology Source Type: research

Coronary in-stent restenosis: predisposing clinical and stent-related factors, diagnostic performance and analyses of inaccuracies in 320-row computed tomography angiography
Abstract The aim of this study was to identify predisposing factors for coronary in-stent restenosis (ISR) and assess its detection by 320-row computed tomography angiography (CTA) using invasive coronary angiography (ICA) as a gold standard. A total of 189 patients (aged 35–79, mean age 56.6, 169 males) with 318 stents underwent ICA within 4 days after CTA. ISR was found in 19 (10.0 %) patients and 25 (7.9 %) stents. At the patient level, the presence of ISR was significantly related to the number of deployed stents (P = 0.026) and body mass index (P = 0.030). At th...
Source: The International Journal of Cardiovascular Imaging - April 22, 2016 Category: Radiology Source Type: research

Echocardiographic agreement in the diagnostic evaluation for infective endocarditis
Abstract Echocardiography is essential for the diagnosis and management of infective endocarditis (IE). However, the reproducibility for the echocardiographic assessment of variables relevant to IE is unknown. Objectives of this study were: (1) To define the reproducibility for IE echocardiographic variables and (2) to describe a methodology for assessing quality in an observational cohort containing site-interpreted data. IE reproducibility was assessed on a subset of echocardiograms from subjects enrolled in the International Collaboration on Endocarditis registry. Specific echocardiographic case report forms we...
Source: The International Journal of Cardiovascular Imaging - April 21, 2016 Category: Radiology Source Type: research

Incremental value of cardiac deformation analysis in acute myocarditis: a cardiovascular magnetic resonance imaging study
Abstract The aim of this study was to assess cardiac deformation patterns in myocarditis applying feature tracking imaging (FTI) to cardiovascular magnetic resonance (CMR) images. Thirty-six patients (31 males) with acute myocarditis and 36 age- and gender-matched healthy volunteers were studied. CMR examinations were performed in a 1.5 T MR-scanner including late gadolinium enhancement (LGE). FTI was applied to standard cine images of long and short axis views. Global peak circumferential, longitudinal and radial systolic strains as well as long axis strain (LAS) were measured. Patients showed significantly ...
Source: The International Journal of Cardiovascular Imaging - April 21, 2016 Category: Radiology Source Type: research

Right ventricular assessment at cardiac MRI: initial clinical experience utilizing an IS-SENSE reconstruction
Abstract Cardiac MR is considered the gold standard in assessing RV function. The purpose of this study is to evaluate the clinical utility of an investigational iterative reconstruction algorithm in the quantitative assessment of RV function. This technique has the potential to improve the clinical utility of CMR in the evaluation of RV pathologies, particularly in patients with dyspnea, by shortening acquisition times without adversely influencing imaging performance. Segmented cine images were acquired on 9 healthy volunteers and 29 patients without documented RV pathologies using conventional GRAPPA acquisitio...
Source: The International Journal of Cardiovascular Imaging - April 18, 2016 Category: Radiology Source Type: research

Echocardiography and magnetic resonance imaging based strain analysis of functional single ventricles: a study of intra- and inter-modality reproducibility
Abstract The purpose of this study was to measure reproducibility in strain measurements by echocardiography and cardiac magnetic resonance imaging (CMR) in functional single ventricles in the Fontan circulation. Fontan echocardiograms and CMRs between 1/2005 and 6/2013 were analyzed retrospectively. Patients were included if studies occurred
Source: The International Journal of Cardiovascular Imaging - April 18, 2016 Category: Radiology Source Type: research

Use of short roll C-arm computed tomography and fully automated 3D analysis tools to guide transcatheter aortic valve replacement
Abstract Determination of the coplanar view is a critical component of transcatheter aortic valve replacement (TAVR). The safety and accuracy of a novel reduced angular range C-arm computed tomography (CACT) approach coupled with a fully automated 3D analysis tool package to predict the coplanar view in TAVR was evaluated. Fifty-seven patients with severe symptomatic aortic stenosis deemed prohibitive-risk for surgery and who underwent TAVR were enrolled. Patients were randomized 2:1 to CACT vs. angiography (control) in estimating the coplanar view. These approaches to determine the coplanar view were compared qua...
Source: The International Journal of Cardiovascular Imaging - April 18, 2016 Category: Radiology Source Type: research

Cardiovascular imaging 2015 in the International Journal of Cardiovascular Imaging
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - April 16, 2016 Category: Radiology Source Type: research

Normal ventricular diameter ratio on CT provides adequate assessment for critical right ventricular strain among patients with acute pulmonary embolism
The objective of this study is to identify a clinical scenario for which normal CT-derived right-to-left ventricular (RV/LV) ratio is sufficient to exclude RV strain or PE-related short-term death. This retrospective cohort study included 579 consecutive subjects (08/2003-03/2010) diagnosed with acute PE with normal CT-RV/LV ratio (45 mm (OR 3.07, 95 % CI 1.56–6.03), age>60 years (OR 2.59, 95 % CI 1.41–4.77), central embolus (OR 1.96, 95 % CI 1.01–3.79), and stage-IV cancer (OR 1.94, 95 % CI 0.99–3.78). If these five factors were all absent (37.1 % of the p...
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Fibrosis assessment by integrated backscatter and its relationship with longitudinal deformation and diastolic function in heart failure with preserved ejection fraction
Abstract Myocardial reflectivity, as assessed by calibrated integrated backscatter (cIB) analysis, is a non-invasive surrogate for the amount of left ventricular (LV) fibrosis. The aim of this study was to assess the myocardial reflectivity pattern in patients with heart failure and preserved ejection fraction (HFpEF), and to evaluate its relationship with longitudinal systolic deformation of LV by 2D-speckle tracking echocardiography, and degree of diastolic dysfunction. Transthoracic echocardiography, myocardial Doppler-derived systolic (Sm) and early diastolic velocity (E′), global longitudinal strain (GL...
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Right atrial emptying fraction non-invasively predicts mortality in pulmonary hypertension
Abstract Right-sided heart failure is the most common cause of death in pulmonary hypertension (PH). Echocardiographic measurements of right atrial (RA) size are associated with worse outcome in PH, however the association between RA function and death in PH has not been well-described. 160 PH patients (World Health Organization groups 1–5) underwent cardiac magnetic resonance imaging (cMRI) and right heart catheterization (RHC) within 6 weeks of each other at a tertiary care academic medical center in the United States. We measured cMRI RA maximum and minimum volumes indexed to body surface area and calcula...
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Decreased left atrial strain parameters are correlated with prolonged total atrial conduction time in lone atrial fibrillation
Abstract To investigate left atrium (LA) strain properties of patients with lone atrial fibrillation (LAF) and to assess relationships between LA strain parameters and total atrial conduction time measured with tissue Doppler imaging (PA-TDI). The study population consisted of 53 patients with LAF. The control group was comprised of 50 normal volunteers. Conventional echocardiography indices were measured. Mitral annular velocities and PA-TDI were assessed with TDI. Two-dimensional speckle-tracking echocardiography (2D-STE) was used to assess LA segmental strain and strain rate. Compared with the control group, PA...
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Coronary computed tomography angiography investigation of the association between left main coronary artery bifurcation angle and risk factors of coronary artery disease
Abstract To explore the association between the left main coronary artery bifurcation angle and common atherosclerotic risk factors with regard to the development of coronary artery disease (CAD) using coronary computed tomography angiography (CCTA). A retrospective review of 196 CCTA cases (129 males, 67 females, mean age 58 ± 10.5 years) was conducted. The bifurcation angle between the left anterior descending (LAD) and left circumflex (LCx) was measured on two-dimensional (2D) and three-dimensional (3D) reconstructed images and the type of plaque and degree of lumen stenosis was assessed to...
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Heart deformation analysis: measuring regional myocardial velocity with MR imaging
Abstract The aim of the present study was to test the hypothesis that heart deformation analysis (HDA) may serve as an alternative for the quantification of regional myocardial velocity. Nineteen healthy volunteers (14 male and 5 female) without documented cardiovascular diseases were recruited following the approval of the institutional review board (IRB). For each participant, cine images (at base, mid and apex levels of the left ventricle [LV]) and tissue phase mapping (TPM, at same short-axis slices of the LV) were acquired within a single magnetic resonance (MR) scan. Regional myocardial velocities in radial ...
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Early vascular healing after titanium–nitride–oxide-coated stent versus platinum–chromium everolimus-eluting stent implantation in patients with acute coronary syndrome
Abstract Data on early vascular healing response of novel stent designs are scarce. In this randomized prospective trial, we sought to compare early neointimal coverage of cobalt–chromium-based titanium–nitride–oxide-coated bioactive stents (CoCr-BAS) versus platinum–chromium everolimus-eluting stents (PtCr-EES) at 2-month follow-up in patients with acute coronary syndrome (ACS). Forty patients with ACS were randomized to receive either CoCr-BAS (n = 19) or PtCr-EES (n = 21). Neointimal strut coverage and strut apposition were examined by optical coherence tomogr...
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Evaluation of myocardial strain and artery elasticity using speckle tracking echocardiography and high-resolution ultrasound in patients with bicuspid aortic valve
Abstract Reduced artery elasticity and reduced myocardial strain were present in patients with bicuspid aortic valve (BAV). Their relation to dilation of proximal aorta is unclear. We aimed to study their relation to dilation of proximal aorta. We studied 57 BAV patients categorized into 2 subgroup according to proximal ascending aortic dimensions (nondilated
Source: The International Journal of Cardiovascular Imaging - April 13, 2016 Category: Radiology Source Type: research

Epicardial fat thickness: distribution and association with diabetes mellitus, hypertension and the metabolic syndrome in the ELSA-Brasil study
In conclusion, the amount of EFT in this large multiethnic population is smaller than reported in other populations. EFT reference values varied across demographic and clinical variables, EFT associations with cardiometabolic variables being largely explained by age, sex, ethnicity and central obesity. Although EFT can help identify individuals at increased cardiometabolic risk, it will likely have a limited additional role compared to current risk stratification strategies. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Sequential radial and circumferential strain and oxidative stress assessment in dogs with tachycardia-induced cardiac dysfunction
Abstract Quantitative analysis of left ventricular (LV) deformation based on two-dimensional speckle tracking echocardiography (2D STE) has increasingly been used to assess segmental and global function because conventional echocardiography is influenced by tethering effects of adjacent myocardium and cardiac translational motion. Hypothesis: (1) 2D STE can be useful to detect subtle regional changes in the LV contractility during development of tachycardia-induced cardiomyopathy (TIC) to heart failure in awake dog; (2) oxidized glutathione (GSSG) and reduced glutathione (GSH) levels are associated with the devel...
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

The advantages of live/real time three-dimensional transesophageal echocardiography during assessments of pulmonary stenosis
This study provides evidence of the incremental value of using 3D-TEE rather than 2D-TEE during assessments of PS, specifically in cases where special conditions (pregnancy, pulmonary regurgitation, and concomitant atrial septal defects) cause recordings of the transvalvular peak gradient to be inaccurate. Therefore, 3D-TEE should be used as a complementary imaging tool to 2D-TEE during routine echocardiographic examinations. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

18 F-FDG PET/CT in the diagnosis of prosthetic valve endocarditis
Abstract Recent studies have shown promising results using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the diagnosis of prosthetic valve endocarditis (PVE). However, previous studies did not include negative controls. The aim of this study was to compare 18F-FDG-uptake around prosthetic aortic valves in patients with and without PVE and to determine the diagnostic performance of 18F-FDG PET/CT in the diagnosis of PVE. 18F-FDG PET/CT examinations in patients with a prosthetic aortic valve performed 2008–2014 were retrieved. Eight patients with a final diagnosis...
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Evaluation for abdominal aortic aneurysms is justified in patients with thoracic aortic aneurysms
Abstract Aortic aneurysms are a significant cause of mortality, and the presence of multiple aneurysms may affect treatment plans. The purpose of this study was to determine the frequency of abdominal aortic aneurysms (AAAs) in patients with thoracic aortic aneurysms (TAAs) and to establish whether patient specific factors, such as gender and comorbidities, influenced the frequency of AAAs, thereby indicating if and when abdominal aortic evaluation is justified. Electronic medical records were reviewed from 1000 patients with a computed tomography (CT) angiogram of the chest and abdomen and a clinical diagnosis o...
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Computed tomography perfusion imaging may predict cognitive impairment in patients with first-time anterior circulation transient ischemic attack
Abstract To determine whether computed tomography perfusion imaging (CTPI)-derived parameters are associated with vascular cognitive impairment (VCI) in patients with transient ischemic attack (TIA). Patients with first-time anterior circulation TIA (diagnosed within 24 h of onset) and normal cognition, treated between August 2009 and August 2014 at the Department of Neurology of Chengdu Military General Hospital, China, were analyzed retrospectively. Patients underwent whole-brain CTPI within 1 week of TIA to detect cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT) and tim...
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Are changes in the extent of left ventricular dyssynchrony as assessed by speckle tracking associated with response to cardiac resynchronization therapy?
Abstract Echocardiographic assessment of left ventricular (LV) dyssynchrony is used to predict response to cardiac resynchronization therapy (CRT). However, the association between reduction in the extent of speckle tracking based LV-dyssynchrony and echocardiographic response to CRT has not been explored yet. The aim of this study was to assess the changes in the extent of LV dyssynchrony as a result of CRT and its association with echocardiographic response to CRT in a large consecutive series of patients. We studied 138 patients with standard CRT indication. Time-based speckle tracking longitudinal strain (max...
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Epicardial myocardial strain abnormalities may identify the earliest stages of arrhythmogenic cardiomyopathy
Abstract The aim of this cohort study was to evaluate the value of echocardiographic multilayer strain analysis in the identification of arrhythmogenic cardiomyopathy (AC) in its earliest stages in which sudden cardiac death can occurs. Twenty seven asymptomatic relatives of AC probands (mean age 39.6 ± 19.5 years, 37 % male) with a desmosomal pathogenic mutation but no additional criteria for AC (group II) were compared to age and sex-matched healthy controls (group I). In addition, 70 patients harboring a pathogenic desmosomal mutation with “definitive” diagnosis of AC (gr...
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Relationship of basal-septal fibrosis with LV outflow tract obstruction in hypertrophic cardiomyopathy: insights from cardiac magnetic resonance analysis
This study aimed to determine a role of local fibrosis in HOCM using cardiac magnetic resonance (CMR). 108 consecutive HCM patients underwent CMR. HOCM was defined as a left ventricular outflow tract (LVOT) pressure gradient ≥30 mmHg at rest. Myocardial mass and fibrosis mass by late gadolinium-enhancement CMR (LGE-CMR) were calculated and the distribution/pattern was analyzed using the AHA 17-segment model. LV ejection fraction (LVEF) was significantly higher in patients with HOCM (n = 19) than in those with nonobstructive HCM (n = 89) (P 
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Triple pigtail technique: a novel way to determine the optimal angle of implantation during transcatheter aortic valve replacement while minimizing contrast load
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

Coarctation of the aorta diagnosed by cardiac computed tomography angiography in a 49-year-old man presenting with acute myocardial infarction
We report the case of a 49-year-old man with acute myocardial infarction and diagnosis of severe aortic coarctation in concomitance with a three-dimensional computed tomography scan. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - March 26, 2016 Category: Radiology Source Type: research

NASCI AHA young investigator finalists 2015
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - March 14, 2016 Category: Radiology Source Type: research

Appropriate use criteria in clinical routine practice: implications in a nuclear cardiology lab
Abstract The efforts for a broad application of the appropriate use criteria to reduce inappropriate nuclear stress testing have frequently been unsuccessful and the reported rates of inappropriateness have varied widely between studies. We sought to analyze the criteria of clinical appropriateness of a cohort of consecutive patients referred to our nuclear cardiology laboratory to perform stress myocardial perfusion imaging (MPI) and to assess the relationships between test appropriateness and the evaluation of ischaemia. A cohort of 251 consecutive patients, admitted to our Institute from January to March 2015, ...
Source: The International Journal of Cardiovascular Imaging - March 10, 2016 Category: Radiology Source Type: research

Enlightenment from a small but rapidly evolving penetrating aortic ulcer
Abstract Penetrating aortic ulcer (PAU) is a pathologic type of acute aortic syndrome and usually locates in the descending aorta. The presentation, behavior and natural history of this disease process have not been clear. Here we report a case in which a rapidly evolving PAU in descending aorta needed aggressive percutaneous interventional treatment. The present case with its unique scenario might draw clinicians’ attention on a “beyond the guidelines” issue. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - March 9, 2016 Category: Radiology Source Type: research

Rest and stress transluminal attenuation gradient and contrast opacification difference for detection of hemodynamically significant stenoses in patients with suspected coronary artery disease
This study evaluated the feasibility of stress 320 detector CT coronary angiography (CTA) derived transluminal attenuation gradient (TAG320) and contrast opacification (CO) difference to detect hemodynamically significant stenoses as determined by invasive fractional flow reserve (FFR ≤ 0.80). Twenty-seven patients, including 51 vessels on rest CTA were studied. 16 (31 %) vessels were not interpretable on stress CTA largely secondary to motion artefacts. Receiver operating characteristic curve analysis showed a comparable area under the curve (AUC) for rest and stress TAG320 (0.78 and 0.75) which was high...
Source: The International Journal of Cardiovascular Imaging - March 7, 2016 Category: Radiology Source Type: research

Serpentine-like right atrial mass and fulminant bilateral pulmonary embolism during treatment with rivaroxaban
Abstract Imaging work-up of a 80-year-old woman with sudden onset of dyspnea during current rivaroxaban therapy: computer tomography angiography revealed fulminant bilateral pulmonary embolism. Furthermore, a serpentine-like huge mass in the right atrium was detected, highly suggestive of thrombus or a giant chiari network, respectively. This case highlights the importance of adequate dose regimen of factor Xa inhibitors, as well as the need of thorough differential diagnostic considerations of net like structures in the right atrium. (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - March 3, 2016 Category: Radiology Source Type: research

Prognostic value of right ventricular free wall strain in pulmonary hypertension patients with pseudo-normalized tricuspid annular plane systolic excursion values
Abstract Pulmonary hypertension (PH) is a progressively fatal disease having a significant impact on right ventricular (RV) function, a major determinant of long-term outcome in PH patients. In our clinic we frequently noticed the combination of PH and reduced RV function, but with discordant Tricuspid Annular Plane Systolic Excursion (TAPSE) values. The present study focuses on whether RV free wall strain measured using 2-dimensional speckle-tracking echocardiography is able to predict mortality in this subgroup of PH patients. 57 patients with PH and RV dysfunction (visual echocardiographic assessment of ≥2) ...
Source: The International Journal of Cardiovascular Imaging - March 1, 2016 Category: Radiology Source Type: research

Reproducibility of serial optical coherence tomography measurements for lumen area and plaque components in humans (The CLI-VAR [Centro per la Lotta Contro l’Infarto-variability] II study)
Abstract Frequency-domain optical coherence tomography (FD-OCT) is a promising intracoronary imaging technique to study atherosclerosis. Indeed, its unprecedented spatial resolution allows the assessment of fibrous cap thickness, lipid pool and features of plaque vulnerability. Aim of this study was to determine the reproducibility of the in vivo FD-OCT measurements of lumen area and plaque components in serial studies. Twenty-six patients undergoing FD-OCT assessment of intermediate lesion during coronary angiography were included in this study. FD-OCT pullbacks were acquired twice from the same coronary segment...
Source: The International Journal of Cardiovascular Imaging - February 11, 2016 Category: Radiology Source Type: research

Lipomatous hypertrophy of the right ventricle and interventricular septum associated with ventricular arrhythmia
(Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - February 11, 2016 Category: Radiology Source Type: research

Assessment of aortic stiffness among patients with systemic lupus erythematosus and rheumatoid arthritis by magnetic resonance imaging
Abstract To evaluate aortic stiffness by MRI in female patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) in comparison to controls. We measured aortic strain, distensibility and pulse wave velocity (PWV) by MRI in 30 SLE patients, 31 RA patients and 53 matched controls. Mean PWV in SLE and RA patients were higher in comparison to controls (9.2 ± 4.4 vs. 7.6 ± 3.0 m/s, p = 0.04) and (6.2 ± 2.3 vs. 5.4 ± 1.7, p = 0.04) respectively. Aortic distensibility among RA patients was significantly lower i...
Source: The International Journal of Cardiovascular Imaging - February 6, 2016 Category: Radiology Source Type: research

Coronary arteries anomalous aortic origin on a computed tomography angiography population: prevalence, characteristics and clinical impact
Abstract Anomalous aortic origin of coronary arteries (AAOCA) is one of the most frequent causes of cardiovascular sudden death among the young population. We aimed to determine the prevalence and anatomic characteristics of AAOCA in a population referred to computed tomography angiography (CTA) and to describe the clinical prognosis of these findings at middle term follow-up. From a total of 3539 CTA, 53 were found to have AAOCA. This population was compared to an age and gender matched control group (n = 106) from the same CTA list. A telephone follow-up to determine cardiac events was conducted, w...
Source: The International Journal of Cardiovascular Imaging - February 6, 2016 Category: Radiology Source Type: research

Echocardiographic assessment of right ventricular functions in patients with proximal right coronary artery chronic total occlusion
Abstract To assess right ventricular functions by echocardiography in patients with proximal right coronary artery (RCA) CTO and correlating it with clinical and angiographic variables. We studied 60 consecutive patients with CTO of the proximal RCA and no other significant lesions in the left coronary system. Echocardiography was performed in order to measure left ventricular (LV) dimensions, LVEF, RV end diastolic area (RVEDA), RV end systolic area (RVESA), RV fractional area change (RVFAC), tricuspid annular plane systolic excursion (TAPSE), Doppler myocardial performance index (MPI), trans-tricuspid E and A wa...
Source: The International Journal of Cardiovascular Imaging - February 5, 2016 Category: Radiology Source Type: research

A simple, fast and reproducible echocardiographic approach to grade left ventricular diastolic function
Abstract The American Society of Echocardiography and European Association of Echocardiography (ASE/EAE) have published an algorithm for the grading of diastolic function. However, the ability to use this algorithm effectively in daily clinical practice has not been investigated. We hypothesized that in some patients it may be difficult to grade diastolic dysfunction with this scheme, since there may be discrepancies in the assessed parameters. The aim of the current study was to test the feasibility of the ASE/EAE algorithm and to compare this with a new Thoraxcenter (TXC) algorithm. The ASE/EAE and TXC algorithm...
Source: The International Journal of Cardiovascular Imaging - February 3, 2016 Category: Radiology Source Type: research

Adaptive anisotropic gaussian filtering to reduce acquisition time in cardiac diffusion tensor imaging
Abstract Diffusion tensor imaging (DTI) is used to quantify myocardial fiber orientation based on helical angles (HA). Accurate HA measurements require multiple excitations (NEX) and/or several diffusion encoding directions (DED). However, increasing NEX and/or DED increases acquisition time (TA). Therefore, in this study, we propose to reduce TA by implementing a 3D adaptive anisotropic Gaussian filter (AAGF) on the DTI data acquired from ex-vivo healthy and infarcted porcine hearts. DTI was performed on ex-vivo hearts [9-healthy, 3-myocardial infarction (MI)] with several combinatio...
Source: The International Journal of Cardiovascular Imaging - February 2, 2016 Category: Radiology Source Type: research

Evaluation of cardiac masses by CMR—strengths and pitfalls: a tertiary center experience
Abstract Cardiovascular magnetic resonance (CMR) imaging is often considered the reference method to assess cardiac tumors. However, little data exists concerning the effectiveness of CMR for the accurate diagnosis of cardiac masses. We sought to understand the diagnostic value of CMR for evaluation of suspected cardiac mass. A total of 249 consecutive CMR cases performed at a single center from January 2005 to June 2013 for evaluation of masses found on echocardiography or computed tomography (CT) were included. All the clinical data and imaging features of these patients were retrospectively reviewed and medical...
Source: The International Journal of Cardiovascular Imaging - February 2, 2016 Category: Radiology Source Type: research

Dose correction for post-contrast T1 mapping of the heart: the MESA study
Abstract Post-contrast myocardial T1 (T1myo,c) values have been shown to be sensitive to myocardial fibrosis. Recent studies have shown differences in results obtained from T1myo,c and extracellular volume fraction (ECV) with respect to percentage fibrosis. By exploring the relationship between blood plasma volume and T1myo,c, the underlying basis for the divergence can be explained. Furthermore, dose administration based on body mass index (BMI), age and gender can mitigate the divergence in results. Inter-subject comparison of T1myo,c required adjustment for dose (in mmol/kg), time and glomerular filtration rat...
Source: The International Journal of Cardiovascular Imaging - February 1, 2016 Category: Radiology Source Type: research

Prognostic evaluation in obese patients using a dedicated multipinhole cadmium-zinc telluride SPECT camera
Abstract The purpose of this study is to evaluate the prognostic value of myocardial perfusion SPECT obtained in CZT cameras (CZT–SPECT) with multipinhole collimation in obese patients. CZT–SPECT may be technically challenging in the obese, and its prognostic value remains largely unknown. Patients underwent single-day, rest/stress (supine and prone) imaging. Images were visually inspected and graded as poor, fair or good/excellent. Summed stress and difference scores (SSS and SDS, respectively) were converted into percentages of total perfusion defect and of ischemic defect by division by the maximum...
Source: The International Journal of Cardiovascular Imaging - February 1, 2016 Category: Radiology Source Type: research

3D-Dixon MRI based volumetry of peri- and epicardial fat
Abstract There is growing evidence that pericardial and epicardial fat volume (PFV, EFV) are associated with cardiovascular risk. We evaluated a novel method for accurate measurement of PFV and EFV using a 3D-Dixon based cardiac magnetic resonance (CMR) approach. An electrocardiography triggered and respiratory navigator gated 3D-gradient echo pulse sequence was used for cardiac Dixon imaging. Based on this sequence, voxels predominantly containing fat were identified and added up for volumetry. After accuracy assessment in phantoms, consisting of muscle tissue and seven different fat samples (50–200 m...
Source: The International Journal of Cardiovascular Imaging - February 1, 2016 Category: Radiology Source Type: research